Cancer Biology & Therapy, Volume 13, Issue 10 (2012)

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Cancer Biology & Therapy, Volume 13, Issue 10 (2012)

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Meeting Report

Meeting Report
Biomarkers—a pot of gold or a can of worms?
Meeting report from the 2nd World Congress on Biomarkers & Clinical Research, 2011, Baltimore, USA
Georg F. Weber, Jeremy Warren, Hitoshi Shoma, Tao Chen, Abdel Halim & Geetika Chakravarty
Pages: 831-835
Published online: 01 Aug 2012
AbstractforBiomarkers—a pot of gold or a can of worms? | Full Text | PDF (330.4 KB)
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Brief Communication

Brief Report
Isocitrate dehydrogenase 1R132H mutation in microglia/macrophages in gliomas
Indication of a significant role of microglia/macrophages in glial tumorigenesis
Ping-Pin Zheng, Marcel van der Weiden, Peter J. van der Spek, Arnaud J.P.E. Vincent & Johan M. Kros
Pages: 836-839
Published online: 01 Aug 2012
AbstractforIsocitrate dehydrogenase 1R132H mutation in microglia/macrophages in gliomas | Full Text | References | PDF (817.8 KB)
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Clinical Study

Article
Recurrent gliomas
Comparison of computed tomography (CT)-guided 125I seed implantation therapy and traditional radiochemotherapy
Xiaokun Hu, Huijuan Qiu, Liang Zhang, Weidong Zhang, Yongqiang Ma, Zhizheng Qiao, Dong Chen, Jianjun Han, Guangfeng Duan & Fujun Zhang
Pages: 840-847
Published online: 01 Aug 2012
AbstractforRecurrent gliomas | Full Text | References | PDF (804.3 KB)
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Research Paper

Article
The DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation
Debolina Ray, Keith R. Murphy & Susannah Gal
Pages: 848-857
Published online: 01 Aug 2012
AbstractforThe DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation | Full Text | References | PDF (753.3 KB) | Supplemental
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Article
Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment
Olga Frolova, Ismael Samudio, Juliana Maria Benito, Rodrigo Jacamo, Steven M. Kornblau, Ana Markovic, Wendy Schober, Hongbo Lu, Yi Hua Qiu, Daniela Buglio, Teresa McQueen, Sherry Pierce, Elizabeth J. Shpall, Sergej Konoplev, Deborah Thomas, Hagop Kantarjian, Richard Lock, Michael Andreeff & Marina Konopleva
Pages: 858-870
Published online: 01 Aug 2012
AbstractforRegulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
Exome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma
Bin Zhou, Astrid Irwanto, Yun-Miao Guo, Jin-Xin Bei, Qiao Wu, Ge Chen, Tai-Ping Zhang, Jin-Jv Lei, Qi-Sheng Feng, Li-Zhen Chen, Jianjun Liu & Yu-Pei Zhao
Pages: 871-879
Published online: 01 Aug 2012
AbstractforExome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
C1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosis
Atsushi Kawabata, Takaya Matsuzuka, Chiyo Doi, Garret Seiler, Jennifer Reischman, Lara Pickel, Rie Ayuzawa, Thu A. Nguyen & Masaaki Tamura
Pages: 880-889
Published online: 01 Aug 2012
AbstractforC1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosis | Full Text | References | PDF (1.2 MB)
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Article
Suppression of CX43 expression by miR-20a in the progression of human prostate cancer
Xin Li, Jin-Hong Pan, Bo Song, En-Qing Xiong, Zhi-Wen Chen, Zhan-Song Zhou & Yong-Ping Su
Pages: 890-898
Published online: 01 Aug 2012
AbstractforSuppression of CX43 expression by miR-20a in the progression of human prostate cancer | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma
Ru Chen, Sheng Pan, NIki A. Ottenhof, Roeland F. de Wilde, Christopher L. Wolfgang, Zhaoli Lane, Jane Post, Mary P. Bronner, Jürgen K. Willmann, Anirban Maitra & Teresa A. Brentnall
Pages: 899-907
Published online: 01 Aug 2012
AbstractforStromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma | Full Text | References | PDF (859.1 KB) | Supplemental
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Article
Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells
Piyanuch Wonganan, Woon-Gye Chung, Saijie Zhu, Kaoru Kiguchi, John DiGiovanni & Zhengrong Cui
Pages: 908-914
Published online: 01 Aug 2012
AbstractforSilencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells | Full Text | References | PDF (684.7 KB)
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Article
Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth
YiWei Zhang, Qi Zhang, Shelya X. Zeng, Yu Zhang, Lindsey D. Mayo & Hua Lu
Pages: 915-924
Published online: 01 Aug 2012
AbstractforInauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells
Venkata Mahidhar Yenugonda, Yali Kong, Tushar B. Deb, Yonghong Yang, Rebecca B. Riggins & Milton L. Brown
Pages: 925-934
Published online: 01 Aug 2012
AbstractforTrans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Preclinical modeling of EGFR inhibitor resistance in head and neck cancer
Kelly M. Quesnelle, Sarah E. Wheeler, Mary K. Ratay & Jennifer R. Grandis
Pages: 935-945
Published online: 01 Aug 2012
AbstractforPreclinical modeling of EGFR inhibitor resistance in head and neck cancer | Full Text | References | PDF (903.5 KB)
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Article
HuR’s post-transcriptional regulation of death receptor 5 in pancreatic cancer cells
Danielle M. Pineda, David W. Rittenhouse, Christopher C. Valley, Joseph A. Cozzitorto, Richard A. Burkhart, Benjamin Leiby, Jordan M. Winter, Matthew C. Weber, Eric R. Londin, Isidore Rigoutsos, Charles J. Yeo, Myriam Gorospe, Agnieska K. Witkiewicz, Jonathan N. Sachs & Jonathan R. Brody
Pages: 946-955
Published online: 01 Aug 2012
AbstractforHuR’s post-transcriptional regulation of death receptor 5 in pancreatic cancer cells | Full Text | References | PDF (1.1 MB) | Supplemental
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Article
Bif-1 suppresses breast cancer cell migration by promoting EGFR endocytic degradation
Kristin B. Runkle, Cheryl L. Meyerkord, Neelam V. Desai, Yoshinori Takahashi & Hong-Gang Wang
Pages: 956-966
Published online: 01 Aug 2012
AbstractforBif-1 suppresses breast cancer cell migration by promoting EGFR endocytic degradation | Full Text | References | PDF (2 MB)
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