Cancer Biology & Therapy, Volume 16, Issue 4 (2015)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Cancer Biology & Therapy, Volume 16, Issue 4 (2015)

See all volumes and issues
Vol 25, 2024 Vol 24, 2023 Vol 23, 2022 Vol 22, 2021 Vol 21, 2020 Vol 20, 2019 Vol 19, 2018 Vol 18, 2017 Vol 17, 2016 Volume 16, 2015 Vol 15, 2014 Vol 14, 2013 Vol 13, 2012 Vol 12, 2011 Vol 11, 2011 Vol 10, 2010 Vol 9, 2010 Vol 8, 2009 Vol 7, 2008 Vol 6, 2007 Vol 5, 2006 Vol 4, 2005 Vol 3, 2004 Vol 2, 2003 Vol 1, 2002
Download citations Download PDFs Download issue

Bedside to Bench Report

Article
Five years of stable disease with maintenance therapy using bevacizumab and tamoxifen in a patient with metastatic breast cancer
Giandomenico Roviello, Edoardo Francini, Armando Perrella, Letizia Laera, Maria Antonietta Mazzei, Susanna Guerrini, Franco Roviello, Daniele Marrelli & Roberto Petrioli
Pages: 493-497
Published online: 03 Apr 2015
AbstractforFive years of stable disease with maintenance therapy using bevacizumab and tamoxifen in a patient with metastatic breast cancer | Full Text | References | PDF (365.2 KB)
  • 971 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
The expression of P2X7 receptors in EPCs and their potential role in the targeting of EPCs to brain gliomas
Jingqin Fang, Xiao Chen, Shunan Wang, Tian Xie, Xuesong Du, Heng Liu, Sumei Wang, Xue Li, Jinhua Chen, Bo Zhang, Huaping Liang, Yizeng Yang & Weiguo Zhang
Pages: 498-510
Published online: 03 Apr 2015
AbstractforThe expression of P2X7 receptors in EPCs and their potential role in the targeting of EPCs to brain gliomas | Full Text | References | PDF (1.2 MB)
  • 917 Views
  • 19 CrossRef citations
  • 0Altmetric
Free Access
Article
HMGB1-mediated autophagy modulates sensitivity of colorectal cancer cells to oxaliplatin via MEK/ERK signaling pathway
Weijun Liu, Zhenyong Zhang, Yongxue Zhang, Xinju Chen, Shikui Guo, Yi Lei, Yu Xu, Chao Ji, Zhigang Bi & Kunhua Wang
Pages: 511-517
Published online: 03 Apr 2015
AbstractforHMGB1-mediated autophagy modulates sensitivity of colorectal cancer cells to oxaliplatin via MEK/ERK signaling pathway | Full Text | References | PDF (656.9 KB)
  • 1813 Views
  • 55 CrossRef citations
  • 0Altmetric
Free Access
Article
Downregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cells
Nirmala Krishnamurthy, Lili Liu, Xiahui Xiong, Junran Zhang & Monica M Montano
Pages: 518-527
Published online: 07 Apr 2015
AbstractforDownregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cells | Full Text | References | PDF (534.3 KB)
  • 885 Views
  • 5 CrossRef citations
  • 0Altmetric
Free Access
Article
RACK1 predicts poor prognosis and regulates progression of esophageal squamous cell carcinoma through its epithelial-mesenchymal transition
Nana Wang, Fang Liu, Fangli Cao, Yibin Jia, Jianbo Wang, Wei Ma, Bingxu Tan, Kai Wang, Qingxu Song & Yufeng Cheng
Pages: 528-540
Published online: 09 Apr 2015
AbstractforRACK1 predicts poor prognosis and regulates progression of esophageal squamous cell carcinoma through its epithelial-mesenchymal transition | Full Text | References | PDF (1.8 MB)
  • 1142 Views
  • 16 CrossRef citations
  • 0Altmetric
Free Access
Article
Downregulation of phosphoglycerate dehydrogenase inhibits proliferation and enhances cisplatin sensitivity in cervical adenocarcinoma cells by regulating Bcl-2 and caspase-3
Zhang Jing, Wei Heng, Liu Xia, Wang Ning, Qi Yafei, Zhang Yao & Zhang Shulan
Pages: 541-548
Published online: 09 Apr 2015
AbstractforDownregulation of phosphoglycerate dehydrogenase inhibits proliferation and enhances cisplatin sensitivity in cervical adenocarcinoma cells by regulating Bcl-2 and caspase-3 | Full Text | References | PDF (609.7 KB)
  • 1594 Views
  • 43 CrossRef citations
  • 0Altmetric
Free Access
Article
Endothelial PAS domain-containing protein 1 confers TKI-resistance by mediating EGFR and MET pathways in non-small cell lung cancer cells
Qiang Zhen, Jun-Feng Liu, Jia-Bao Liu, Ren-Feng Wang, Wei-Wei Chu, Ya-Xiao Zhang, Guo-Liang Tan, Xiao-Jian Zhao & Bao-Lei Lv
Pages: 549-557
Published online: 13 Apr 2015
AbstractforEndothelial PAS domain-containing protein 1 confers TKI-resistance by mediating EGFR and MET pathways in non-small cell lung cancer cells | Full Text | References | PDF (807.3 KB) | Supplemental
  • 944 Views
  • 11 CrossRef citations
  • 0Altmetric
Free Access
Article
Radioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α
Jae-Sung Kim, Sun Young Kim, Minyoung Lee, Sung Hyun Kim, Sang-Man Kim & Eun Ju Kim
Pages: 558-566
Published online: 13 Apr 2015
AbstractforRadioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α | Full Text | References | PDF (692.5 KB)
  • 1172 Views
  • 22 CrossRef citations
  • 0Altmetric
Free Access
Article
Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells
A Grimaldi, D Santini, S Zappavigna, A Lombardi, G Misso, M Boccellino, V Desiderio, P P Vitiello, G Di Lorenzo, A Zoccoli, F Pantano & M Caraglia
Pages: 567-579
Published online: 11 Apr 2015
AbstractforAntagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells | Full Text | References | PDF (1.2 MB)
  • 1725 Views
  • 42 CrossRef citations
  • 0Altmetric
Free Access
Article
Co-targeting of Akt and Myc inhibits viability of lymphoma cells from Lck-Dlx5 mice
Yinfei Tan, Eleonora Sementino, Jianming Pei, Yuwaraj Kadariya, Timothy K Ito & Joseph R Testa
Pages: 580-588
Published online: 11 Apr 2015
AbstractforCo-targeting of Akt and Myc inhibits viability of lymphoma cells from Lck-Dlx5 mice | Full Text | References | PDF (646.8 KB) | Supplemental
  • 1118 Views
  • 15 CrossRef citations
  • 0Altmetric
Free Access
Article
Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking
Xingfeng Bao, Wanjun Zheng, Naoko Hata Sugi, Kishan L Agarwala, Qunli Xu, Zichun Wang, Karen Tendyke, Winnie Lee, Lana Parent, Wei Li, Hongsheng Cheng, Yongchun Shen, Noel Taylor, Zoltan Dezso, Hong Du, Yoshihiko Kotake, Nanding Zhao, John Wang, Maarten Postema, Mary Woodall-Jappe, Yasutaka Takase, Toshimitsu Uenaka, David G I Kingston & Kenichi Nomoto
Pages: 589-601
Published online: 13 Apr 2015
AbstractforSmall molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1777 Views
  • 27 CrossRef citations
  • 0Altmetric
Free Access
Article
Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma
Yun-Rong Zhu, Han Min, Jian-Feng Fang, Feng Zhou, Xiong-Wei Deng & Yun-Qing Zhang
Pages: 602-609
Published online: 14 Apr 2015
AbstractforActivity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma | Full Text | References | PDF (922.5 KB)
  • 1087 Views
  • 32 CrossRef citations
  • 0Altmetric
Free Access
Article
Pre-clinical activity of PR-104 as monotherapy and in combination with sorafenib in hepatocellular carcinoma
Maria R Abbattista, Stephen M F Jamieson, Yongchuan Gu, Jennifer E Nickel, Susan M Pullen, Adam V Patterson, William R Wilson & Christopher P Guise
Pages: 610-622
Published online: 14 Apr 2015
AbstractforPre-clinical activity of PR-104 as monotherapy and in combination with sorafenib in hepatocellular carcinoma | Full Text | References | PDF (867.2 KB)
  • 1723 Views
  • 26 CrossRef citations
  • 0Altmetric
Free Access
Article
Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway
Qingchun Mu, Lijun Wang, Fengbo Yu, Haijun Gao, Ting Lei, Peiwen Li, Pengfei Liu, Xu Zheng, Xitong Hu, Yong Chen, Zhenfeng Jiang, Arash J Sayari, Jia Shen & Haiyan Huang
Pages: 623-633
Published online: 15 Apr 2015
AbstractforImp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway | Full Text | References | PDF (1.3 MB)
  • 2183 Views
  • 57 CrossRef citations
  • 0Altmetric
Free Access
Article
Blocking M2 muscarinic receptor signaling inhibits tumor growth and reverses epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC)
Qingnan Zhao, Xiajing Gu, Chun Zhang, Qin Lu, Hongzhuan Chen & Lu Xu
Pages: 634-643
Published online: 15 Apr 2015
AbstractforBlocking M2 muscarinic receptor signaling inhibits tumor growth and reverses epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) | Full Text | References | PDF (764.5 KB) | Supplemental
  • 1298 Views
  • 25 CrossRef citations
  • 0Altmetric
Free Access

Explore articles

Explore the most recently published articles

Mechanism investigation of Forsythoside A against esophageal squamous cell carcinoma in vitro and in vivo
Yingying Yang et al.
Article | Published online: 24 Jul 2024
Open Access
Association between the IL1B-511 C>T polymorphism and the risk of hematologic malignancies: data from a meta-analysis
Fabíola Silva Alves-Hanna et al.
Review Article | Published online: 22 Jul 2024
Open Access
Natural killer cell memory: challenges and opportunities for cancer immunotherapy
Yuhua Qu et al.
Review Article | Published online: 10 Jul 2024
Open Access
Jmjd2c maintains the ALDHbri+ cancer stemness with transcription factor SOX2 in lung squamous cell carcinoma
Min Wang et al.
Article | Published online: 8 Jul 2024
Open Access