Autophagy, Volume 17, Issue 7 (2021)

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Autophagy, Volume 17, Issue 7 (2021)

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Editor’s Corner

Article
Not lowering the bar, just providing a step stool
Vojo Deretic & Daniel J. Klionsky
Pages: 1569-1570
Published online: 21 Jun 2021
AbstractforNot lowering the bar, just providing a step stool | Full Text | PDF (233.1 KB) | EPUB
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Review

Regulation and repurposing of nutrient sensing and autophagy in innate immunity
Julia Sanchez-Garrido & Avinash R. Shenoy
Pages: 1571-1591
Published online: 05 Jul 2020
AbstractforRegulation and repurposing of nutrient sensing and autophagy in innate immunity | Full Text | References | PDF (1.4 MB) | EPUB
  • 10307 Views
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Research Paper

Article
Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway
Zu-Guo Zheng, Si-Tong Zhu, Hui-Min Cheng, Xin Zhang, Gang Cheng, Pyone Myat Thu, Supeng Perry Wang, Hui-Jun Li, Ming Ding, Lei Qiang, Xiao-Wei Chen, Qing Zhong, Ping Li & Xiaojun Xu
Pages: 1592-1613
Published online: 20 May 2020
AbstractforDiscovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway | Full Text | References | PDF (14.4 MB) | EPUB | Supplemental
  • 13463 Views
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Article
Autophagy coupled to translation is required for long-term memory
Kiran Pandey, Xiao-Wen Yu, Adam Steinmetz & Cristina M. Alberini
Pages: 1614-1635
Published online: 17 Jun 2020
AbstractforAutophagy coupled to translation is required for long-term memory | Full Text | References | PDF (10.5 MB) | EPUB | Supplemental
  • 2815 Views
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Article
Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy
Damian Gatica, Xin Wen, Heesun Cheong & Daniel J. Klionsky
Pages: 1636-1648
Published online: 17 Jun 2020
AbstractforVac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy | Full Text | References | PDF (7.4 MB) | EPUB | Supplemental
  • 1397 Views
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Article
An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1
Bora Lee, Hyejin Shin, Ji-Eun Oh, Jaekyoung Park, Mira Park, Seung Chel Yang, Jin-Hyun Jun, Seok-Ho Hong, Haengseok Song & Hyunjung Jade Lim
Pages: 1649-1666
Published online: 17 Jun 2020
AbstractforAn autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1 | Full Text | References | PDF (16.8 MB) | EPUB | Supplemental
  • 4156 Views
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Article
MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma
Qingwen Zhu, Qicheng Zhang, Miao Gu, Kaiwen Zhang, Tian Xia, Siyu Zhang, Wenhui Chen, Haimeng Yin, Hui Yao, Yue Fan, Si Pan, Haijing Xie, Huiting Liu, Tianyi Cheng, Panpan Zhang, Ting Zhang, Bo You & Yiwen You
Pages: 1667-1683
Published online: 05 Jul 2020
AbstractforMIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma | Full Text | References | PDF (21.3 MB) | EPUB | Supplemental
  • 7670 Views
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Article
LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13
Yuanyuan Chu, Yingjin Kang, Cong Yan, Cuiwei Yang, Tao Zhang, Huanhuan Huo & Yanfen Liu
Pages: 1684-1699
Published online: 26 Jun 2020
AbstractforLUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13 | Full Text | References | PDF (10.3 MB) | EPUB | Supplemental
  • 9220 Views
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Article
Eicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux
Takeshi Yamamoto, Yoshitsugu Takabatake, Satoshi Minami, Shinsuke Sakai, Ryuta Fujimura, Atsushi Takahashi, Tomoko Namba-Hamano, Jun Matsuda, Tomonori Kimura, Isao Matsui, Jun-Ya Kaimori, Hiroaki Takeda, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita & Yoshitaka Isaka
Pages: 1700-1713
Published online: 28 Jun 2020
AbstractforEicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux | Full Text | References | PDF (20.9 MB) | EPUB | Supplemental
  • 8673 Views
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Article
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1
Daniel Peña-Oyarzun, Marcelo Rodriguez-Peña, Francesca Burgos-Bravo, Angelo Vergara, Catalina Kretschmar, Cristian Sotomayor-Flores, Cesar A. Ramirez-Sarmiento, Humbert De Smedt, Montserrat Reyes, William Perez, Vicente A. Torres, Eugenia Morselli, Francisco Altamirano, Christian A. M. Wilson, Joseph A. Hill, Sergio Lavandero & Alfredo Criollo
Pages: 1714-1728
Published online: 30 Jun 2020
AbstractforPKD2/polycystin-2 induces autophagy by forming a complex with BECN1 | Full Text | References | PDF (7.7 MB) | EPUB | Supplemental
  • 2787 Views
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Article
RETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism
Debdatto Mookherjee, Subhrangshu Das, Rukmini Mukherjee, Manindra Bera, Swadhin Chandra Jana, Saikat Chakrabarti & Oishee Chakrabarti
Pages: 1729-1752
Published online: 01 Jul 2020
AbstractforRETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism | Full Text | References | PDF (25.4 MB) | EPUB | Supplemental
  • 3499 Views
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Article
Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice
Qian Huang, Yunhao Liu, Shiyang Zhang, Yi Tian Yap, Wei Li, David Zhang, Ahmad Gardner, Ling Zhang, Shizheng Song, Rex A Hess & Zhibing Zhang
Pages: 1753-1767
Published online: 17 Jul 2020
AbstractforAutophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice | Full Text | References | PDF (10.3 MB) | EPUB | Supplemental
  • 4910 Views
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Article
HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons
Maryline Santerre, Sterling P Arjona, Charles Ns Allen, Shannon Callen, Shilpa Buch & Bassel E Sawaya
Pages: 1768-1782
Published online: 23 Apr 2021
AbstractforHIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 2082 Views
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Autophagic Punctum

Article
The BPAN and intellectual disability disease proteins WDR45 and WDR45B modulate autophagosome-lysosome fusion
Cuicui Ji & Yan G. Zhao
Pages: 1783-1784
Published online: 09 Jun 2021
AbstractforThe BPAN and intellectual disability disease proteins WDR45 and WDR45B modulate autophagosome-lysosome fusion | Full Text | References | PDF (218.8 KB) | EPUB
  • 1256 Views
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Article Commentary
A unique COPII population in plant autophagy
Yonglun Zeng & Liwen Jiang
Pages: 1785-1787
Published online: 28 May 2021
AbstractforA unique COPII population in plant autophagy | Full Text | References | PDF (486 KB) | EPUB
  • 967 Views
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Article
Cell type-specific YAP1-WWTR1/TAZ transcriptional responses after autophagy perturbations are determined by levels of α-catenins (CTNNA1 and CTNNA3)
Mariana Pavel, So Jung Park, Radu Tanasa & David C. Rubinsztein
Pages: 1788-1790
Published online: 04 Jun 2021
AbstractforCell type-specific YAP1-WWTR1/TAZ transcriptional responses after autophagy perturbations are determined by levels of α-catenins (CTNNA1 and CTNNA3) | Full Text | References | PDF (521.5 KB) | EPUB
  • 1196 Views
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Article Commentary
When the autophagy protein ATG16L1 met the ciliary protein IFT20
Asma Boukhalfa, Federica Roccio, Nicolas Dupont, Patrice Codogno & Etienne Morel
Pages: 1791-1793
Published online: 31 May 2021
AbstractforWhen the autophagy protein ATG16L1 met the ciliary protein IFT20 | Full Text | References | PDF (759 KB) | EPUB
  • 821 Views
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Article Commentary
Multiplexed suppression of TOR complex 1 induces autophagy during starvation
Tomoyuki Fukuda & Kazuhiro Shiozaki
Pages: 1794-1795
Published online: 14 Jun 2021
AbstractforMultiplexed suppression of TOR complex 1 induces autophagy during starvation | Full Text | References | PDF (252.8 KB) | EPUB
  • 3276 Views
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Article
Lipid-mediated impairment of axonal lysosome transport contributing to autophagic stress
Joseph C. Roney, Sunan Li, Tamar Farfel-Becker, Ning Huang, Tao Sun, Yuxiang Xie, Xiu-Tang Cheng, Mei-Yao Lin, Frances M. Platt & Zu-Hang Sheng
Pages: 1796-1798
Published online: 30 Jun 2021
AbstractforLipid-mediated impairment of axonal lysosome transport contributing to autophagic stress | Full Text | References | PDF (601.5 KB) | EPUB
  • 1896 Views
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Article Commentary
iCAL: a new pipeline to investigate autophagy selectivity and cancer
Weizhi Zhang, Zhu Han, Yu Xue & Da Jia
Pages: 1799-1801
Published online: 28 Jun 2021
AbstractforiCAL: a new pipeline to investigate autophagy selectivity and cancer | Full Text | References | PDF (2.3 MB) | EPUB
  • 1312 Views
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Article Commentary
AMBRA1 has an impact on melanoma development beyond autophagy
Luca Di Leo & Daniela De Zio
Pages: 1802-1803
Published online: 22 Jun 2021
AbstractforAMBRA1 has an impact on melanoma development beyond autophagy | Full Text | References | PDF (709.9 KB) | EPUB
  • 706 Views
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