Cancer Biology & Therapy, Volume 15, Issue 4 (2014)

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Cancer Biology & Therapy, Volume 15, Issue 4 (2014)

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Commentary

Article Commentary
Not so WEE
Targeting G2/M to kill mesothelioma cells
Paul Dent
Pages: 351-352
Published online: 04 Feb 2014
AbstractforNot so WEE | Full Text | References | PDF (119.5 KB)
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Review

Review Article
The status of zinc in the development of hepatocellular cancer
An important, but neglected, clinically established relationship
Leslie C Costello & Renty B Franklin
Pages: 353-360
Published online: 21 Jan 2014
AbstractforThe status of zinc in the development of hepatocellular cancer | Full Text | References | PDF (2 MB)
  • 1408 Views
  • 22 CrossRef citations
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Review Article
Strategic evaluation of interventions to prevent consequential late proctitis after prostate radiation therapy
New clinical trial designs should be considered
Timothy N Showalter, Nolan A Wages & Nitin Ohri
Pages: 361-364
Published online: 04 Feb 2014
AbstractforStrategic evaluation of interventions to prevent consequential late proctitis after prostate radiation therapy | Full Text | References | PDF (680.7 KB)
  • 589 Views
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Clinical Study

Article
Ki-67 index as a prognostic factor of subsequent lapatinib-based therapy in HER2-positive metastatic breast cancer with resistance to trastuzumab
Li Bian, Tao Wang, Shao-hua Zhang, Hui-qiang Zhang, Yun-fei Guo, Ge Du, Wang Li, Shi-kai Wu, San-tai Song & Ze-fei Jiang
Pages: 365-370
Published online: 14 Jan 2014
AbstractforKi-67 index as a prognostic factor of subsequent lapatinib-based therapy in HER2-positive metastatic breast cancer with resistance to trastuzumab | Full Text | References | PDF (807.8 KB)
  • 683 Views
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Article
Lower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy
Victorien MT van Verschuer, Bernadette AM Heemskerk-Gerritsen, Carolien HM van Deurzen, Inge-Marie Obdeijn, Madeleine MA Tilanus-Linthorst, Cornelis Verhoef, Marjanka K Schmidt, Linetta B Koppert, Maartje J Hooning & Caroline Seynaeve
Pages: 371-379
Published online: 14 Jan 2014
AbstractforLower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy | Full Text | References | PDF (979.6 KB)
  • 538 Views
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Research Paper

Article
Abrogating G2/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma
Paola Indovina, Eleonora Marcelli, Domenico Di Marzo, Nadia Casini, Iris Maria Forte, Francesca Giorgi, Luigi Alfano, Francesca Pentimalli & Antonio Giordano
Pages: 380-388
Published online: 14 Jan 2014
AbstractforAbrogating G2/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma | Full Text | References | PDF (6 MB)
  • 1905 Views
  • 23 CrossRef citations
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Article
Non-invasive fecal metabonomic detection of colorectal cancer
Lee Cheng Phua, Xiu Ping Chue, Poh Koon Koh, Peh Yean Cheah, Han Kiat Ho & Eric Chun Yong Chan
Pages: 389-397
Published online: 14 Jan 2014
AbstractforNon-invasive fecal metabonomic detection of colorectal cancer | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1941 Views
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Article
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin
Xing-qi Li, Zhi-gang Ouyang, Sheng-hua Zhang, Hong Liu, Yue Shang, Yi Li & Yong-su Zhen
Pages: 398-408
Published online: 14 Jan 2014
AbstractforSynergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin | Full Text | References | PDF (3.2 MB)
  • 850 Views
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Article
Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells
Potential effects on the tumor microenvironment
Jayoung Kim, Samantha Morley, Minh Le, Denis Bedoret, Dale T Umetsu, Dolores Di Vizio & Michael R Freeman
Pages: 409-418
Published online: 14 Jan 2014
AbstractforEnhanced shedding of extracellular vesicles from amoeboid prostate cancer cells | Full Text | References | PDF (2.1 MB)
  • 2043 Views
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Article
MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines
Masoumeh Azizi, Ladan Teimoori-Toolabi, Mohsen Karimi Arzanani, Kayhan Azadmanesh, Pezhman Fard-Esfahani & Sirous Zeinali
Pages: 419-427
Published online: 21 Jan 2014
AbstractforMicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines | Full Text | References | PDF (1.6 MB)
  • 1264 Views
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Article
Loss of GATA3 in bladder cancer promotes cell migration and invasion
Yi Li, Hitoshi Ishiguro, Takashi Kawahara, Eiji Kashiwagi, Koji Izumi & Hiroshi Miyamoto
Pages: 428-435
Published online: 21 Jan 2014
AbstractforLoss of GATA3 in bladder cancer promotes cell migration and invasion | Full Text | References | PDF (1.7 MB)
  • 1481 Views
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Article
Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma
Dirk Theile, Zoltan Gal, Rolf Warta, Juan Pablo Rigalli, Bernd Lahrmann, Niels Grabe, Christel Herold-Mende, Gerhard Dyckhoff & Johanna Weiss
Pages: 436-442
Published online: 21 Jan 2014
AbstractforAntiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma | Full Text | References | PDF (1.3 MB)
  • 795 Views
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Article
Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model
Chunsheng Li, Ann-Marie Chacko, Jia Hu, Kosei Hasegawa, Jennifer Swails, Luigi Grasso, Wafik S El-Deiry, Nicholas Nicolaides, Vladimir R Muzykantov, Chaitanya R Divgi & George Coukos
Pages: 443-451
Published online: 19 Feb 2014
AbstractforAntibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model | Full Text | References | PDF (4.4 MB) | Supplemental
  • 1265 Views
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Article
Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer
Beth Overley-Adamson, Carol M Artlett, Connie Stephens, Sihem Sassi-Gaha, Ransome D Weis & James D Thacker
Pages: 452-462
Published online: 04 Feb 2014
AbstractforTargeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer | Full Text | References | PDF (1.4 MB)
  • 2241 Views
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Article
All-trans-retinoic acid antagonizes the hedgehog pathway by inducing patched
Alexander M Busch, Fabrizio Galimberti, Kristen E Nehls, Monic Roengvoraphoj, David Sekula, Bin Li, Yongli Guo, James DiRenzo, Steven N Fiering, Michael J Spinella, David J Robbins, Vincent A Memoli, Sarah J Freemantle & Ethan Dmitrovsky
Pages: 463-472
Published online: 04 Feb 2014
AbstractforAll-trans-retinoic acid antagonizes the hedgehog pathway by inducing patched | Full Text | References | PDF (2 MB) | Supplemental
  • 916 Views
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Article
Resveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors
Edward J Wu, Dennis J Goussetis, Elspeth Beauchamp, Ewa M Kosciuczuk, Jessica K Altman, Elizabeth A Eklund & Leonidas C Platanias
Pages: 473-478
Published online: 04 Feb 2014
AbstractforResveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors | Full Text | References | PDF (1 MB)
  • 729 Views
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