Human Vaccines & Immunotherapeutics, Volume 8, Issue 11 (2012)

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Human Vaccines & Immunotherapeutics, Volume 8, Issue 11 (2012)

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Editor's Corner

Editorial
Letter from the Editor
Ronald Ellis & Eva M. Riedmann
Page: 1549
Published online: 01 Nov 2012
CitationforLetter from the Editor | Full Text | PDF (73 KB)
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News, Policy & Profiles

News
Human Vaccines: News
Eva M. Riedmann
Pages: 1550-1553
Published online: 01 Nov 2012
AbstractforHuman Vaccines: News | Full Text | PDF (106.1 KB)
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Editor's Corner

Editorial
Highlights of the DNA Vaccines 2011 Meeting
Kenneth E. Ugen & David B. Weiner
Page: 1554
Published online: 01 Nov 2012
CitationforHighlights of the DNA Vaccines 2011 Meeting | Full Text | PDF (71.7 KB)
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Research Paper

Article
IL-4 and IFN-γ induced by human immunodeficiency virus vaccine in a schistosome infection model
Jiangmei Yin, Anlan Dai, Tatiana Arango, Ravi S. Kasinathan, Robert M. Greenberg & Jean D. Boyer
Pages: 1555-1563
Published online: 01 Nov 2012
AbstractforIL-4 and IFN-γ induced by human immunodeficiency virus vaccine in a schistosome infection model | Full Text | References | PDF (4.6 MB)
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Article
Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA
Thomas L. Richie, Yupin Charoenvit, Ruobing Wang, Judith E. Epstein, Richard C. Hedstrom, Sanjai Kumar, Thomas C. Luke, Daniel A. Freilich, Joao C. Aguiar, John B. Sacci, Jr.Martha Sedegah, Ronald A. Nosek, Jr.Patricia De La Vega, Mara P. Berzins, Victoria F. Majam, Esteban N. Abot, Harini Ganeshan, Nancy O. Richie, Jo Glenna Banania, Maria Fe B. Baraceros, Tanya G. Geter, Robin Mere, Lolita Bebris, Keith Limbach, Bradley W. Hickey, David E. Lanar, Jennifer Ng, Meng Shi, Peter M. Hobart, Jon A. Norman, Lorraine A. Soisson, Michael R. Hollingdale, William O. Rogers, Denise L. Doolan & Stephen L. Hoffman
Pages: 1564-1584
Published online: 01 Nov 2012
AbstractforClinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA | Full Text | References | PDF (48.3 MB) | Supplemental
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Review

Review Article
Development of a multicomponent Staphylococcus aureus vaccine designed to counter multiple bacterial virulence factors
Annaliesa S. Anderson, Alita A. Miller, Robert G.K. Donald, Ingrid L. Scully, Jasdeep S. Nanra, David Cooper & Kathrin U. Jansen
Pages: 1585-1594
Published online: 24 Aug 2012
AbstractforDevelopment of a multicomponent Staphylococcus aureus vaccine designed to counter multiple bacterial virulence factors | Full Text | References | PDF (737 KB)
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Research Paper

Article
Preclinical evaluation of the immunogenicity and safety of plasmid DNA-based prophylactic vaccines for human cytomegalovirus
Jukka Hartikka, Vesselina Bozoukova, Jane Morrow, Denis Rusalov, Mark Shlapobersky, Qun Wei, Sou Boutsaboualoy, Ming Ye, Mary K. Wloch, John Doukas, Sean M. Sullivan, Alain Rolland & Larry R. Smith
Pages: 1595-1606
Published online: 24 Aug 2012
AbstractforPreclinical evaluation of the immunogenicity and safety of plasmid DNA-based prophylactic vaccines for human cytomegalovirus | Full Text | References | PDF (1.1 MB)
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Article
Generation of antigen-specific immunity following systemic immunization with DNA vaccine encoding CCL25 chemokine immunoadjuvant
Noshin Kathuria, Kimberly A. Kraynyak, Diane Carnathan, Michael Betts, David B. Weiner & Michele A. Kutzler
Pages: 1607-1619
Published online: 01 Nov 2012
AbstractforGeneration of antigen-specific immunity following systemic immunization with DNA vaccine encoding CCL25 chemokine immunoadjuvant | Full Text | References | PDF (2.2 MB)
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Article
IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques
Rashmi Jalah, Vainav Patel, Viraj Kulkarni, Margherita Rosati, Candido Alicea, Brunda Ganneru, Agneta von Gegerfelt, Wensheng Huang, Yongjun Guan, Kate E. Broderick, Niranjan Y Sardesai, Celia LaBranche, David C. Montefiori, George N. Pavlakis & Barbara K. Felber
Pages: 1620-1629
Published online: 16 Aug 2012
AbstractforIL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques | Full Text | References | PDF (1.1 MB)
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Article
DNA prime-protein boost using subtype consensus Env was effective in eliciting neutralizing antibody responses against subtype BC HIV-1 viruses circulating in China
Mingshun Zhang, Lu Zhang, Chunhua Zhang, Kunxue Hong, Yiming Shao, Zuhu Huang, Shixia Wang & Shan Lu
Pages: 1630-1637
Published online: 30 Oct 2012
AbstractforDNA prime-protein boost using subtype consensus Env was effective in eliciting neutralizing antibody responses against subtype BC HIV-1 viruses circulating in China | Full Text | References | PDF (1.9 MB)
  • 530 Views
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Article
Pilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates
Shixia Wang, Michael Kishko, Shengqin Wan, Yan Wang, Frank Brewster, Glenda E. Gray, Avye Violari, John L. Sullivan, Mohan Somasundaran, Katherine Luzuriaga & Shan Lu
Pages: 1638-1647
Published online: 01 Nov 2012
AbstractforPilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates | Full Text | References | PDF (2 MB)
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Article
DNA-based HIV vaccines do not induce generalized activation in mucosal tissue T cells
Morgan A. Reuter, Sally Yuan, Preston A. Marx, Michele A. Kutzler, David B. Weiner & Michael R. Betts
Pages: 1648-1653
Published online: 30 Oct 2012
AbstractforDNA-based HIV vaccines do not induce generalized activation in mucosal tissue T cells | Full Text | References | PDF (1.2 MB)
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Review

Review Article
Co-expression of HIV-1 virus-like particles and granulocyte-macrophage colony stimulating factor by GEO-D03 DNA vaccine
Michael Hellerstein, Yongxian Xu, Tracie Marino, Shan Lu, Hong Yi, Elizabeth R. Wright & Harriet L. Robinson
Pages: 1654-1658
Published online: 30 Oct 2012
AbstractforCo-expression of HIV-1 virus-like particles and granulocyte-macrophage colony stimulating factor by GEO-D03 DNA vaccine | Full Text | References | PDF (585.6 KB)
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Research Paper

Article
Sequential administration of cytokine genes to enhance cellular immune responses and CD4+ T memory cells during DNA vaccination
Baowei Su, Junpeng Wang, Gan Zhao, Xiao J Wang, Jinyao Li & Bin Wang
Pages: 1659-1667
Published online: 01 Nov 2012
AbstractforSequential administration of cytokine genes to enhance cellular immune responses and CD4+ T memory cells during DNA vaccination | Full Text | References | PDF (1.8 MB)
  • 661 Views
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Article
Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice
Devon J. Shedlock, Kendra T. Talbott, Stephan J. Wu, Christine M. Wilson, Kar Muthumani, Jean D. Boyer, Niranjan Y Sardesai, Sita Awasthi & David B. Weiner
Pages: 1668-1681
Published online: 01 Nov 2012
AbstractforVaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice | Full Text | References | PDF (1.8 MB)
  • 975 Views
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Review

Review Article
Harnessing DNA-induced immune responses for improving cancer vaccines
Andrés A. Herrada, Nicole Rojas-Colonelli, Paula González-Figueroa, Jonathan Roco, César Oyarce, Maarten A Ligtenberg & Alvaro Lladser
Pages: 1682-1693
Published online: 30 Oct 2012
AbstractforHarnessing DNA-induced immune responses for improving cancer vaccines | Full Text | References | PDF (1,002.9 KB)
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Review Article
What you always needed to know about electroporation based DNA vaccines
Anita Gothelf & Julie Gehl
Pages: 1694-1702
Published online: 30 Oct 2012
AbstractforWhat you always needed to know about electroporation based DNA vaccines | Full Text | References | PDF (939.9 KB)
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Short Report

Brief Report
A multiagent filovirus DNA vaccine delivered by intramuscular electroporation completely protects mice from ebola and Marburg virus challenge
Rebecca J. Grant-Klein, Nicole M. Van Deusen, Catherine V. Badger, Drew Hannaman, Lesley C. Dupuy & Connie S. Schmaljohn
Pages: 1703-1706
Published online: 24 Aug 2012
AbstractforA multiagent filovirus DNA vaccine delivered by intramuscular electroporation completely protects mice from ebola and Marburg virus challenge | Full Text | References | PDF (1.3 MB)
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Research Paper

Article
Contactless magneto-permeabilization for intracellular plasmid DNA delivery in-vivo
Thomas J. Kardos & Dietmar P. Rabussay
Pages: 1707-1713
Published online: 16 Aug 2012
AbstractforContactless magneto-permeabilization for intracellular plasmid DNA delivery in-vivo | Full Text | References | PDF (1.5 MB)
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Article
Electroporation driven delivery of both an IL-12 expressing plasmid and cisplatin synergizes to inhibit B16 melanoma tumor growth through an NK cell mediated tumor killing mechanism
Ha Kim & Jeong-Im Sin
Pages: 1714-1721
Published online: 01 Nov 2012
AbstractforElectroporation driven delivery of both an IL-12 expressing plasmid and cisplatin synergizes to inhibit B16 melanoma tumor growth through an NK cell mediated tumor killing mechanism | Full Text | References | PDF (1.2 MB)
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Article
Electrogenetherapy of B16.F10 murine melanoma tumors with an interleukin-28 expressing DNA plasmid
Kevin Shah, Richard J. Connolly, Taryn Chapman, Mark J. Jaroszeski & Kenneth E. Ugen
Pages: 1722-1728
Published online: 01 Nov 2012
AbstractforElectrogenetherapy of B16.F10 murine melanoma tumors with an interleukin-28 expressing DNA plasmid | Full Text | References | PDF (1.1 MB)
  • 556 Views
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Article
Non-contact helium-based plasma for delivery of DNA vaccines
Enhancement of humoral and cellular immune responses
Richard J. Connolly, Taryn Chapman, Andrew M. Hoff, Michele A. Kutzler, Mark J. Jaroszeski & Kenneth E. Ugen
Pages: 1729-1733
Published online: 16 Aug 2012
AbstractforNon-contact helium-based plasma for delivery of DNA vaccines | Full Text | References | PDF (869.9 KB)
  • 660 Views
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Review

Review Article
Plasmid IL-12 electroporation in melanoma
Edward Cha & Adil Daud
Pages: 1734-1738
Published online: 01 Nov 2012
AbstractforPlasmid IL-12 electroporation in melanoma | Full Text | References | PDF (606.4 KB)
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