OncoImmunology, Volume 1, Issue 7 (2012)

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OncoImmunology, Volume 1, Issue 7 (2012)

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Editorial

Editorial
T-cell dependent immunoselection
Mads Hald Andersen
Page: 1003
Published online: 01 Oct 2012
CitationforT-cell dependent immunoselection | Full Text | References | PDF (69.8 KB)
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Original Research

Article
Immunotherapy with HER-2 and VEGF peptide mimics plus metronomic paclitaxel causes superior antineoplastic effects in transplantable and transgenic mouse models of human breast cancer
Kevin C. Foy, Megan J. Miller, Nicanor Moldovan, Tatjana Bozanovic, William E. Carson & Pravin T. P. Kaumaya
Pages: 1004-1016
Published online: 01 Oct 2012
AbstractforImmunotherapy with HER-2 and VEGF peptide mimics plus metronomic paclitaxel causes superior antineoplastic effects in transplantable and transgenic mouse models of human breast cancer | Full Text | References | PDF (3.3 MB)
  • 750 Views
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Article
Primary sterile necrotic cells fail to cross-prime CD8+ T cells
Jaba Gamrekelashvili, Lars A. Ormandy, Markus M. Heimesaat, Carsten J. Kirschning, Michael P. Manns, Firouzeh Korangy & Tim F. Greten
Pages: 1017-1026
Published online: 01 Oct 2012
AbstractforPrimary sterile necrotic cells fail to cross-prime CD8+ T cells | Full Text | References | PDF (758.7 KB)
  • 847 Views
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Article
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance
Tatsuaki Mizutani, Nina Neugebauer, Eva M. Putz, Nadine Moritz, Olivia Simma, Eva Zebedin-Brandl, Dagmar Gotthardt, Wolfgang Warsch, Eva Eckelhart, Hans-Peter Kantner, Ulrich Kalinke, Stefan Lienenklaus, Siegfried Weiss, Birgit Strobl, Mathias Müller, Veronika Sexl & Dagmar Stoiber
Pages: 1027-1037
Published online: 01 Oct 2012
AbstractforConditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Single low-dose cyclophosphamide combined with interleukin-12 gene therapy is superior to a metronomic schedule in inducing immunity against colorectal carcinoma in mice
Mariana Malvicini, Laura Alaniz, Juan Bayo, Mariana Garcia, Flavia Piccioni, Esteban Fiore, Catalina Atorrasagasti, Jorge B. Aquino, Pablo Matar & Guillermo Mazzolini
Pages: 1038-1047
Published online: 01 Oct 2012
AbstractforSingle low-dose cyclophosphamide combined with interleukin-12 gene therapy is superior to a metronomic schedule in inducing immunity against colorectal carcinoma in mice | Full Text | References | PDF (853.8 KB)
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Article
Combined vaccination with HER-2 peptide followed by therapy with VEGF peptide mimics exerts effective anti-tumor and anti-angiogenic effects in vitro and in vivo
Kevin C. Foy, Megan J. Miller, Nicanor Moldovan, William E. Carson & Pravin T. P. Kaumaya
Pages: 1048-1060
Published online: 01 Oct 2012
AbstractforCombined vaccination with HER-2 peptide followed by therapy with VEGF peptide mimics exerts effective anti-tumor and anti-angiogenic effects in vitro and in vivo | Full Text | References | PDF (2 MB)
  • 877 Views
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Article
B7-H1 limits the entry of effector CD8+ T cells to the memory pool by upregulating Bim
Rachel M Gibbons, Xin Liu, Vesna Pulko, Susan M Harrington, Christopher J Krco, Eugene D Kwon & Haidong Dong
Pages: 1061-1073
Published online: 01 Oct 2012
AbstractforB7-H1 limits the entry of effector CD8+ T cells to the memory pool by upregulating Bim | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands
Stephan Munich, Andrea Sobo-Vujanovic, William J. Buchser, Donna Beer-Stolz & Nikola L. Vujanovic
Pages: 1074-1083
Published online: 01 Oct 2012
AbstractforDendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands | Full Text | References | PDF (699.5 KB)
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Article
Loss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8+ T-cell immunity
Matthew D. Brown, Robbert van der Most, Justin B. Vivian, Richard A. Lake, Irma Larma, Bruce W. S. Robinson & Andrew J. Currie
Pages: 1084-1094
Published online: 01 Oct 2012
AbstractforLoss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8+ T-cell immunity | Full Text | References | PDF (856.5 KB)
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Article
Detecting T-cell reactivity to whole cell vaccines
Proof of concept analysis of T-cell response to K562 cell antigens in CML patients
Ana Brusic, Ursula Hainz, Martha Wadleigh, Donna Neuberg, Mei Su, Christine M. Canning, Daniel J. DeAngelo, Richard M. Stone, Jeng-Shin Lee, Richard C. Mulligan, Jerome Ritz, Glenn Dranoff, Tetsuro Sasada & Catherine J. Wu
Pages: 1095-1103
Published online: 01 Oct 2012
AbstractforDetecting T-cell reactivity to whole cell vaccines | Full Text | References | PDF (808.1 KB)
  • 763 Views
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Open Access
Article
Expression of MHC Class I on breast cancer cells correlates inversely with HER2 expression
Masayuki Inoue, Kousaku Mimura, Shinichiro Izawa, Kensuke Shiraishi, Ayako Inoue, Shugo Shiba, Mitsuaki Watanabe, Takanori Maruyama, Yoshihiko Kawaguchi, Shingo Inoue, Tomonori Kawasaki, Aniruddha Choudhury, Ryohei Katoh, Hideki Fujii, Rolf Kiessling & Koji Kono
Pages: 1104-1110
Published online: 01 Oct 2012
AbstractforExpression of MHC Class I on breast cancer cells correlates inversely with HER2 expression | Full Text | References | PDF (983.6 KB)
  • 1880 Views
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Review

Review Article
Trial watch
Dendritic cell-based interventions for cancer therapy
Lorenzo Galluzzi, Laura Senovilla, Erika Vacchelli, Alexander Eggermont, Wolf Hervé Fridman, Jérôme Galon, Catherine Sautès-Fridman, Eric Tartour, Laurence Zitvogel & Guido Kroemer
Pages: 1111-1134
Published online: 01 Oct 2012
AbstractforTrial watch | Full Text | References | PDF (378.5 KB)
  • 2642 Views
  • 128 CrossRef citations
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Review Article
Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations
Elio Schouppe, Patrick De Baetselier, Jo A. Van Ginderachter & Adelaida Sarukhan
Pages: 1135-1145
Published online: 01 Oct 2012
AbstractforInstruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations | PDF (964.4 KB)
  • 850 Views
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Review Article
A model for cancer-suppressive inflammation
Ole Audun Werner Haabeth, Bjarne Bogen & Alexandre Corthay
Pages: 1146-1155
Published online: 01 Oct 2012
AbstractforA model for cancer-suppressive inflammation | Full Text | References | PDF (648.7 KB)
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Point-of-View

Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
Marcus Schmidt, Patrick Micke, Mathias Gehrmann & Jan G. Hengstler
Pages: 1156-1158
Published online: 01 Oct 2012
AbstractforImmunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors | PDF (638.6 KB)
  • 512 Views
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Author's View

Friend or foe
A novel role of β-defensins in tumor development
Johann Röhrl, Edward K. Geissler & Thomas Hehlgans
Pages: 1159-1160
Published online: 01 Oct 2012
AbstractforFriend or foe | Full Text | References | PDF (226.2 KB)
  • 413 Views
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Redirecting neutrophils against bladder cancer cells by BCG and Smac mimetic combination
Goodwin Jinesh G.Ashish M. Kamat
Pages: 1161-1162
Published online: 01 Oct 2012
AbstractforRedirecting neutrophils against bladder cancer cells by BCG and Smac mimetic combination | Full Text | References | PDF (371.2 KB)
  • 652 Views
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Hunting for clues
Regulatory T cells and colorectal cancer
Awen Gallimore & Andrew Godkin
Pages: 1163-1164
Published online: 01 Oct 2012
AbstractforHunting for clues | Full Text | References | PDF (231.8 KB)
  • 426 Views
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Rage mediated DAMP signaling in intestinal tumorigenesis
Jarom Heijmans, Nikè V. J. A. Büller, Vanesa Muncan & Gijs R. van den Brink
Pages: 1165-1166
Published online: 01 Oct 2012
AbstractforRage mediated DAMP signaling in intestinal tumorigenesis | Full Text | References | PDF (214.8 KB)
  • 569 Views
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Open Access
Combination of vaccine and immune checkpoint inhibitor is safe with encouraging clinical activity
Ravi A Madan, Christopher R. Heery & James L. Gulley
Pages: 1167-1168
Published online: 01 Oct 2012
AbstractforCombination of vaccine and immune checkpoint inhibitor is safe with encouraging clinical activity | Full Text | References | PDF (114.3 KB)
  • 743 Views
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Open Access
Personalizing immunotherapy
Balancing predictability and precision
Zvia Agur & Stanimir Vuk-Pavlović
Pages: 1169-1171
Published online: 01 Oct 2012
AbstractforPersonalizing immunotherapy | Full Text | References | PDF (274.2 KB)
  • 535 Views
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Open Access
Combinatorial Immunotherapy
PD-1 may not be LAG-ing behind any more
Meghan E. Turnis, Alan J. Korman, Charles G. Drake & Dario A.A. Vignali
Pages: 1172-1174
Published online: 01 Oct 2012
AbstractforCombinatorial Immunotherapy | Full Text | References | PDF (435.7 KB)
  • 1056 Views
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RhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment
Neveen Said & Dan Theodorescu
Pages: 1175-1177
Published online: 01 Oct 2012
AbstractforRhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment | Full Text | References | PDF (346.5 KB)
  • 669 Views
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Activation of systemic antitumor immunity via TRAIL-induced apoptosis
Britnie R. James & Thomas S. Griffith
Pages: 1178-1180
Published online: 01 Oct 2012
AbstractforActivation of systemic antitumor immunity via TRAIL-induced apoptosis | Full Text | References | PDF (284.8 KB)
  • 437 Views
  • 4 CrossRef citations
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Open Access
Interleukin-2 treatment of tumor patients can expand regulatory T cells
Marc Beyer
Pages: 1181-1182
Published online: 01 Oct 2012
AbstractforInterleukin-2 treatment of tumor patients can expand regulatory T cells | Full Text | References | PDF (239.9 KB)
  • 502 Views
  • 10 CrossRef citations
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Blocking IL-10 enhances bacillus Calmette-Guérin induced T helper Type 1 immune responses and anti-bladder cancer immunity
Yi Luo
Pages: 1183-1185
Published online: 01 Oct 2012
AbstractforBlocking IL-10 enhances bacillus Calmette-Guérin induced T helper Type 1 immune responses and anti-bladder cancer immunity | Full Text | References | PDF (318 KB)
  • 582 Views
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Tumor-infiltrating B cells
The ignored players in tumor immunology
Michael Linnebacher & Claudia Maletzki
Pages: 1186-1188
Published online: 01 Oct 2012
AbstractforTumor-infiltrating B cells | Full Text | References | PDF (373.1 KB)
  • 1713 Views
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Open Access
Rapamycin
A rheostat for CD8+ T-cell-mediated tumor therapy
Rupesh K. Srivastava, Adam Utley & Protul A. Shrikant
Pages: 1189-1190
Published online: 01 Oct 2012
AbstractforRapamycin | Full Text | References | PDF (193.9 KB)
  • 641 Views
  • 10 CrossRef citations
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Targeting the right regulatory T-cell population for tumor immunotherapy
Vivian L. Weiss, Timothy H. Lee, Elizabeth M. Jaffee & Todd D. Armstrong
Pages: 1191-1193
Published online: 01 Oct 2012
AbstractforTargeting the right regulatory T-cell population for tumor immunotherapy | Full Text | References | PDF (256 KB)
  • 531 Views
  • 14 CrossRef citations
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Cancer testis antigens
A new paradigm for cancer therapy
Anil Suri, Shikha Saini, Abhilasha Sinha, Sumit Agarwal, Archana Verma, Deepak Parashar, Swarnendra Singh, Namita Gupta & Nirmala Jagadish
Pages: 1194-1196
Published online: 01 Oct 2012
AbstractforCancer testis antigens | Full Text | References | PDF (281.4 KB)
  • 1086 Views
  • 33 CrossRef citations
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Ipilimumab in a Phase II trial of melanoma patients with brain metastases
Kim Margolin
Pages: 1197-1199
Published online: 01 Oct 2012
AbstractforIpilimumab in a Phase II trial of melanoma patients with brain metastases | Full Text | References | PDF (219.4 KB)
  • 718 Views
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Opposing consequences of signaling through EGF family members
Escape from CTLs could be a bait for NK cells
Rolf Kiessling, Riki Okita, Dimitrios Mougiakakos, Yumeng Mao, Dhifaf Sarhan, Erik Wennerberg, Barbara Seliger, Andreas Lundqvist, Kousaku Mimura & Koji Kono
Pages: 1200-1201
Published online: 01 Oct 2012
AbstractforOpposing consequences of signaling through EGF family members | Full Text | References | PDF (197.9 KB)
  • 564 Views
  • 2 CrossRef citations
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Flipping the script on macrophages in leiomyosarcoma
Badreddin Edris, Kipp Weiskopf, Irving L Weissman & Matt van de Rijn
Pages: 1202-1204
Published online: 01 Oct 2012
AbstractforFlipping the script on macrophages in leiomyosarcoma | Full Text | References | PDF (277.7 KB)
  • 837 Views
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Stromal CEACAM1 expression regulates colorectal cancer metastasis
Azadeh Arabzadeh & Nicole Beauchemin
Pages: 1205-1207
Published online: 01 Oct 2012
AbstractforStromal CEACAM1 expression regulates colorectal cancer metastasis | Full Text | References | PDF (402.4 KB)
  • 582 Views
  • 4 CrossRef citations
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Specificity may be overrated in cancer immunotherapy
Getting to know the nonspecific side of memory T Cells
Gail D. Sckisel & William J. Murphy
Pages: 1208-1210
Published online: 01 Oct 2012
AbstractforSpecificity may be overrated in cancer immunotherapy | Full Text | References | PDF (421.5 KB)
  • 447 Views
  • 2 CrossRef citations
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CD4 responses against IDO
Mads Hald Andersen
Pages: 1211-1212
Published online: 01 Oct 2012
AbstractforCD4 responses against IDO | Full Text | References | PDF (182.8 KB)
  • 571 Views
  • 10 CrossRef citations
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Targeted cancer immunotherapy
Mimicking physiological trans-presentation of IL-15
Dafne Müller
Pages: 1213-1214
Published online: 01 Oct 2012
AbstractforTargeted cancer immunotherapy | Full Text | References | PDF (313.3 KB)
  • 596 Views
  • 5 CrossRef citations
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Production of epitope-specific antibodies using peptide-CpG-ODN-liposome complex without carriers and their application as a cancer vaccine in mice
YoungHee Lee & Hyung-Joo Kwon
Pages: 1215-1217
Published online: 01 Oct 2012
AbstractforProduction of epitope-specific antibodies using peptide-CpG-ODN-liposome complex without carriers and their application as a cancer vaccine in mice | Full Text | References | PDF (422.7 KB)
  • 537 Views
  • 1 CrossRef citations
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Activation of dendritic cells by tumor cell death
Mara Cirone, Livia Di Renzo, Lavinia V. Lotti, Valeria Conte, Pankaj Trivedi, Roberta Santarelli, Roberta Gonnella, Luigi Frati & Alberto Faggioni
Pages: 1218-1219
Published online: 01 Oct 2012
AbstractforActivation of dendritic cells by tumor cell death | Full Text | References | PDF (227.3 KB)
  • 743 Views
  • 39 CrossRef citations
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Opposing effects of androgen ablation on immune function in prostate cancer
Shuai Tang & Purnima Dubey
Pages: 1220-1221
Published online: 01 Oct 2012
AbstractforOpposing effects of androgen ablation on immune function in prostate cancer | Full Text | References | PDF (344.7 KB)
  • 525 Views
  • 4 CrossRef citations
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