OncoImmunology, Volume 3, Issue 6 (2014)

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OncoImmunology, Volume 3, Issue 6 (2014)

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Original Research

Article
Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies
Sabina Sangaletti, Claudio Tripodo, Paola Portararo, Matteo Dugo, Caterina Vitali, Laura Botti, Carla Guarnotta, Barbara Cappetti, Alessandro Gulino, Ilaria Torselli, Patrizia Casalini, Claudia Chiodoni & Mario P Colombo
Article: e28989
Published online: 05 Jun 2014
AbstractforStromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies | Full Text | References | PDF (18.1 MB)
  • 1155 Views
  • 28 CrossRef citations
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Article
Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer
Eveline Faes van’t Hull, Sylvian Bron, Luc Henry, Assia Ifticene-Treboux, Riccardo Turrini, George Coukos, Jean-François Delaloye & Marie-Agnès Doucey
Article: e29080
Published online: 25 Jun 2014
AbstractforBone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer | Full Text | References | PDF (3.8 MB) | Supplemental
  • 965 Views
  • 19 CrossRef citations
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Free Access
Article
Characterization of an adaptive immune response in microsatellite-instable colorectal cancer
Florence Boissière-Michot, Gwendal Lazennec, Hélène Frugier, Marta Jarlier, Lise Roca, Jacqueline Duffour, Emilie Du Paty, Daniel Laune, France Blanchard, Florence Le Pessot, Jean-Christophe Sabourin & Frédéric Bibeau
Article: e29256
Published online: 25 Jun 2014
AbstractforCharacterization of an adaptive immune response in microsatellite-instable colorectal cancer | Full Text | References | PDF (19 MB) | Supplemental
  • 1674 Views
  • 69 CrossRef citations
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Brief Report

Brief Report
Tumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy
Lisa DS Johnson, Nancy J Nesslinger, Paul A Blood, Navraj Chima, Lindsay R Richier, Charles Ludgate, Howard H Pai, Jan T Lim, Brad H Nelson, Maria T Vlachaki & Julian J Lum
Article: e29243
Published online: 25 Jun 2014
AbstractforTumor-associated autoantibodies correlate with poor outcome in prostate cancer patients treated with androgen deprivation and external beam radiation therapy | Full Text | References | PDF (828 KB)
  • 622 Views
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Review

Review Article
Trial Watch:
Oncolytic viruses for cancer therapy
Jonathan Pol, Norma Bloy, Florine Obrist, Alexander Eggermont, Jérôme Galon, Isabelle Cremer, Philippe Erbs, Jean-Marc Limacher, Xavier Preville, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e28694
Published online: 01 Jun 2014
AbstractforTrial Watch: | Full Text | References | PDF (388.1 KB)
  • 2914 Views
  • 89 CrossRef citations
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Author's View

Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
Jérémy Goc, Wolf-Herman Fridman, Scott A Hammond, Catherine Sautès-Fridman & Marie-Caroline Dieu-Nosjean
Article: e28976
Published online: 29 May 2014
AbstractforTertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses | Full Text | References | PDF (765 KB)
  • 1524 Views
  • 25 CrossRef citations
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Trial watch
Immunostimulatory cytokines in cancer therapy
Erika Vacchelli, Fernando Aranda, Florine Obrist, Alexander Eggermont, Jérôme Galon, Isabelle Cremer, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e29030
Published online: 03 Jun 2014
AbstractforTrial watch | Full Text | References | PDF (1 MB)
  • 1517 Views
  • 49 CrossRef citations
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Radiation therapy combined with Listeria monocytogenes-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model
Joanne YH Lim, Dirk G Brockstedt, Edith M Lord & Scott A Gerber
Article: e29028
Published online: 03 Jun 2014
AbstractforRadiation therapy combined with Listeria monocytogenes-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model | Full Text | References | PDF (722.5 KB)
  • 951 Views
  • 10 CrossRef citations
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Immune cells in pancreatic cancer
Joining the dark side
Yaqing Zhang, Florencia McAllister & Marina Pasca di Magliano
Article: e29125
Published online: 05 Jun 2014
AbstractforImmune cells in pancreatic cancer | Full Text | References | PDF (847.3 KB)
  • 872 Views
  • 5 CrossRef citations
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The hedgehog’s trick for escaping immunosurveillance
The molecular mechanisms driving myeloid-derived suppressor cell recruitment in hedgehog signaling-dependent tumors
Jingwu Xie
Article: e29180
Published online: 05 Jun 2014
AbstractforThe hedgehog’s trick for escaping immunosurveillance | Full Text | References | PDF (740.7 KB)
  • 598 Views
  • 9 CrossRef citations
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Monoclonal antibody targeting of mononuclear cell chemokines driving malignant pleural effusion
Antonia Marazioti & Georgios T Stathopoulos
Article: e29195
Published online: 11 Jun 2014
AbstractforMonoclonal antibody targeting of mononuclear cell chemokines driving malignant pleural effusion | Full Text | References | PDF (1,004.4 KB)
  • 482 Views
  • 4 CrossRef citations
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‘Hardcore’ OX40+ immunosuppressive regulatory T cells in hepatic cirrhosis and cancer
Silvia Piconese, Eleonora Timperi & Vincenzo Barnaba
Article: e29257
Published online: 17 Jun 2014
Abstractfor‘Hardcore’ OX40+ immunosuppressive regulatory T cells in hepatic cirrhosis and cancer | Full Text | References | PDF (814.9 KB)
  • 644 Views
  • 11 CrossRef citations
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Antibody-based depletion of Foxp3+ T cells potentiates antitumor immune memory stimulated by mTOR inhibition
Hyung L Kim
Article: e29081
Published online: 18 Jun 2014
AbstractforAntibody-based depletion of Foxp3+ T cells potentiates antitumor immune memory stimulated by mTOR inhibition | Full Text | References | PDF (785.3 KB)
  • 408 Views
  • 1 CrossRef citations
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BRAF-targeted therapy alters the functions of intratumoral CD4+ T cells to inhibit melanoma progression
Ping-Chih Ho & Susan M Kaech
Article: e29126
Published online: 18 Jun 2014
AbstractforBRAF-targeted therapy alters the functions of intratumoral CD4+ T cells to inhibit melanoma progression | Full Text | References | PDF (858 KB)
  • 636 Views
  • 4 CrossRef citations
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Pancreatic cancer
Hurdles in the engineering of CAR-based immunotherapies
Daniel Abate-Daga, Steven A Rosenberg & Richard A Morgan
Article: e29194
Published online: 18 Jun 2014
AbstractforPancreatic cancer | Full Text | References | PDF (2.5 MB)
  • 1095 Views
  • 6 CrossRef citations
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LTX-315 (Oncopore™)
A short synthetic anticancer peptide and novel immunotherapeutic agent
Ketil André Camilio, Øystein Rekdal & Baldur Sveinbjörnsson
Article: e29181
Published online: 25 Jun 2014
AbstractforLTX-315 (Oncopore™) | Full Text | References | PDF (905.9 KB)
  • 1838 Views
  • 42 CrossRef citations
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Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes
Lidia Robert, Christina Harview, Ryan Emerson, Xiaoyan Wang, Stephen Mok, Blanca Homet, Begonya Comin-Anduix, Richard C Koya, Harlan Robins, Paul C Tumeh & Antoni Ribas
Article: e29244
Published online: 25 Jun 2014
AbstractforDistinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes | Full Text | References | PDF (780.4 KB)
  • 2095 Views
  • 75 CrossRef citations
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A novel preclinical murine model of immune-mediated metastatic dormancy
Irene Romero, Federico Garrido & Angel M Garcia-Lora
Article: e29258
Published online: 25 Jun 2014
AbstractforA novel preclinical murine model of immune-mediated metastatic dormancy | Full Text | References | PDF (899.5 KB)
  • 490 Views
  • 2 CrossRef citations
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STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression
Nina Le Bert, Adeline R Lam, Samantha SW Ho, Yu J Shen, Mo M Liu & Stephan Gasser
Article: e29259
Published online: 25 Jun 2014
AbstractforSTING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression | Full Text | References | PDF (709.9 KB)
  • 1244 Views
  • 18 CrossRef citations
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Immunological targeting of cytomegalovirus for glioblastoma therapy
Smita K Nair, John H Sampson & Duane A Mitchell
Article: e29289
Published online: 25 Jun 2014
AbstractforImmunological targeting of cytomegalovirus for glioblastoma therapy | Full Text | References | PDF (814.9 KB)
  • 775 Views
  • 22 CrossRef citations
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Personal neoantigen cancer vaccines
The momentum builds
Edward F Fritsch, Nir Hacohen & Catherine J Wu
Article: e29311
Published online: 25 Jun 2014
AbstractforPersonal neoantigen cancer vaccines | Full Text | References | PDF (1.3 MB)
  • 2886 Views
  • 48 CrossRef citations
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Hormesis in cancer immunology
Does the quantity of an immune reactant matter?
Oliver MT Pearce, Heinz Läubli, Jack Bui & Ajit Varki
Article: e29312
Published online: 25 Jun 2014
AbstractforHormesis in cancer immunology | Full Text | References | PDF (1.1 MB)
  • 702 Views
  • 16 CrossRef citations
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Potential utility of the pan-Bcl-2 inhibitor GX15–070 (obatoclax) in cancer immunotherapy
Peter S Kim & Jeffrey Schlom
Article: e29351
Published online: 25 Jun 2014
AbstractforPotential utility of the pan-Bcl-2 inhibitor GX15–070 (obatoclax) in cancer immunotherapy | Full Text | References | PDF (938 KB)
  • 444 Views
  • 5 CrossRef citations
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Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis
<span lang="EN-US">Glycans make the difference</span>
Diego O Croci & Gabriel A Rabinovich
Article: e29380
Published online: 25 Jun 2014
AbstractforLinking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis | Full Text | References | PDF (860.4 KB)
  • 788 Views
  • 15 CrossRef citations
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Open Access
Cellular immunotherapy directed against human cytomegalovirus as a novel approach for glioblastoma treatment
Andrea Schuessler, David G Walker & Rajiv Khanna
Article: e29381
Published online: 25 Jun 2014
AbstractforCellular immunotherapy directed against human cytomegalovirus as a novel approach for glioblastoma treatment | Full Text | References | PDF (769.9 KB)
  • 538 Views
  • 6 CrossRef citations
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The fatal alliance of cancer and T cells
How pancreatic tumor cells gather immunosuppressive T cells
Evelin Grage-Griebenow, Heiner Schäfer & Susanne Sebens
Article: e29382
Published online: 25 Jun 2014
AbstractforThe fatal alliance of cancer and T cells | Full Text | References | PDF (1.1 MB)
  • 592 Views
  • 8 CrossRef citations
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PD-L1 expression and tumor-infiltrating lymphocytes
Revisiting the antitumor immune response potential in breast cancer
Kurt A Schalper
Article: e29288
Published online: 25 Jun 2014
AbstractforPD-L1 expression and tumor-infiltrating lymphocytes | Full Text | References | PDF (795.3 KB)
  • 1516 Views
  • 51 CrossRef citations
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Targeting COX-2 abrogates mammary tumorigenesis
Breaking cancer-associated suppression of immunosurveillance
Nune Markosyan, Edward P Chen & Emer M Smyth
Article: e29287
Published online: 30 Jun 2014
AbstractforTargeting COX-2 abrogates mammary tumorigenesis | Full Text | References | PDF (717.2 KB)
  • 614 Views
  • 12 CrossRef citations
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Trial Watch
Toll-like receptor agonists in oncological indications
Fernando Aranda, Erika Vacchelli, Florine Obrist, Alexander Eggermont, Jérôme Galon, Catherine Sautès-Fridman, Isabelle Cremer, Jan Henrik ter Meulen, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e29179
Published online: 01 Aug 2014
AbstractforTrial Watch | Full Text | References | PDF (322.7 KB)
  • 1543 Views
  • 67 CrossRef citations
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