Cell Cycle, Volume 11, Issue 21 (2012)

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Cell Cycle, Volume 11, Issue 21 (2012)

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Editorials: Cell Cycle Features

Article Commentary
The transformative promise of aging science
David Stipp
Pages: 3903-3904
Published online: 14 Sep 2012
AbstractforThe transformative promise of aging science | Full Text | References | PDF (81.6 KB)
  • 377 Views
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Article Commentary
Human embryonic stem cells
Living on the edge
Vivian Gama & Mohanish Deshmukh
Pages: 3905-3906
Published online: 03 Oct 2012
CitationforHuman embryonic stem cells | Full Text | References | PDF (191.4 KB)
  • 583 Views
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Article Commentary
Dynamic nature of heterochromatin highlighted by a HP1Swi6-dependent gene silencing mechanism
Marc Bühler & Sebastian Hiller
Pages: 3907-3908
Published online: 03 Oct 2012
CitationforDynamic nature of heterochromatin highlighted by a HP1Swi6-dependent gene silencing mechanism | Full Text | References | PDF (215.7 KB)
  • 453 Views
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Article Commentary
An expanded role of the tumor suppressor TSC1 in T cell tolerance
Xiao-Ping Zhong
Pages: 3909-3910
Published online: 03 Oct 2012
CitationforAn expanded role of the tumor suppressor TSC1 in T cell tolerance | Full Text | References | PDF (145 KB)
  • 433 Views
  • 5 CrossRef citations
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Article Commentary
“Remembering” tissue-specific transcription patterns through mitosis
Stephan Kadauke & Gerd A. Blobel
Pages: 3911-3912
Published online: 03 Oct 2012
Citationfor“Remembering” tissue-specific transcription patterns through mitosis | Full Text | References | PDF (86.1 KB)
  • 607 Views
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Cell Cycle News & Views

Article Commentary
Cyclin-dependent kinase 4/6 inhibition in cancer therapy
Neil Johnson & Geoffrey I. Shapiro
Page: 3913
Published online: 03 Oct 2012
First Page PreviewforCyclin-dependent kinase 4/6 inhibition in cancer therapy | Full Text | References | PDF (412.3 KB)
  • 688 Views
  • 17 CrossRef citations
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Article Commentary
ORCA is regulated by ubiquitin-mediated degradation to control Orc2 function
Amy E. Ikui
Page: 3914
Published online: 03 Oct 2012
First Page PreviewforORCA is regulated by ubiquitin-mediated degradation to control Orc2 function | Full Text | References | PDF (412.2 KB)
  • 397 Views
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Article Commentary
New functions for ecotropic viral integration site 1 (EVI1), an oncogene causing aggressive malignant disease
Rotraud Wieser
Page: 3915
Published online: 03 Oct 2012
First Page PreviewforNew functions for ecotropic viral integration site 1 (EVI1), an oncogene causing aggressive malignant disease | Full Text | References | PDF (412.2 KB)
  • 406 Views
  • 5 CrossRef citations
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Article Commentary
Addicted to PAR?
A closer look at PARP inhibitor sensitivity
Matthias Altmeyer
Page: 3916
Published online: 03 Oct 2012
First Page PreviewforAddicted to PAR? | Full Text | References | PDF (412.3 KB)
  • 441 Views
  • 1 CrossRef citations
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Article Commentary
UnCHKed DNA replication
A stressful matter
Jennifer L. Gryp & Gustavo J. Gutierrez
Pages: 3917-3918
Published online: 03 Oct 2012
First Page PreviewforUnCHKed DNA replication | Full Text | References | PDF (412.3 KB)
  • 396 Views
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Extra Views

Glucose—a sweet way to die
Metabolic switching modulates tumor cell death
Marion MacFarlane, Gemma L. Robinson & Kelvin Cain
Pages: 3919-3925
Published online: 14 Sep 2012
AbstractforGlucose—a sweet way to die | Full Text | References | PDF (936 KB)
  • 1093 Views
  • 27 CrossRef citations
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Hypoxia and gerosuppression: The mTOR saga continues
Olga V. Leontieva & Mikhail V Blagosklonny
Pages: 3926-3931
Published online: 17 Sep 2012
AbstractforHypoxia and gerosuppression: The mTOR saga continues | PDF (1.5 MB)
  • 432 Views
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Perspective

The real face of HIF1α in the tumor process
Matthias Kappler, Helge Taubert, Johannes Schubert, Dirk Vordermark & Alexander W. Eckert
Pages: 3932-3936
Published online: 17 Sep 2012
AbstractforThe real face of HIF1α in the tumor process | PDF (1 MB)
  • 423 Views
  • 27 CrossRef citations
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Understanding the origins of UV-induced recombination through manipulation of sister chromatid cohesion
Shay Covo, Wenjian Ma, James W. Westmoreland, Dmitry A. Gordenin & Michael A. Resnick
Pages: 3937-3944
Published online: 17 Sep 2012
AbstractforUnderstanding the origins of UV-induced recombination through manipulation of sister chromatid cohesion | Full Text | References | PDF (1.3 MB)
  • 639 Views
  • 11 CrossRef citations
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Review

Review Article
Local and global functions of Timeless and Tipin in replication fork protection
Adam R. Leman & Eishi Noguchi
Pages: 3945-3955
Published online: 17 Sep 2012
AbstractforLocal and global functions of Timeless and Tipin in replication fork protection | PDF (546 KB)
  • 894 Views
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Report

Article
Ketone bodies and two-compartment tumor metabolism: Stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells
Ubaldo E. Martinez-Outschoorn, Zhao Lin, Diana Whitaker-Menezes, Anthony Howell, Michael P. Lisanti & Federica Sotgia
Pages: 3956-3963
Published online: 19 Sep 2012
AbstractforKetone bodies and two-compartment tumor metabolism: Stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells | PDF (2.5 MB) | Supplemental
  • 1475 Views
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Article
Ketone body utilization drives tumor growth and metastasis
Ubaldo E. Martinez-Outschoorn, Zhao Lin, Diana Whitaker-Menezes, Anthony Howell, Federica Sotgia & Michael P. Lisanti
Pages: 3964-3971
Published online: 19 Sep 2012
AbstractforKetone body utilization drives tumor growth and metastasis | PDF (1.6 MB) | Supplemental
  • 1991 Views
  • 129 CrossRef citations
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Article
The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis
Gloria Bonuccelli, Remedios Castello-Cros, Franco Capozza, Ubaldo E. Martinez-Outschoorn, Zhao Lin, Aristotelis Tsirigos, Jiao Xuanmao, Diana Whitaker-Menezes, Anthony Howell, Michael P. Lisanti & Federica Sotgia
Pages: 3972-3982
Published online: 09 Oct 2012
AbstractforThe milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis | Full Text | References | PDF (3.2 MB) | Supplemental
  • 2264 Views
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Article
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network
Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart & Judith L. Campbell
Pages: 3983-3996
Published online: 17 Sep 2012
AbstractforDNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network | Full Text | References | PDF (2 MB) | Supplemental
  • 2333 Views
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Article
Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway
Miriam B.F. Werneck, Eugênio Hottz, Patrícia T. Bozza & João P.B. Viola
Pages: 3997-4008
Published online: 19 Sep 2012
AbstractforCyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway | Full Text | References | PDF (3.1 MB)
  • 1320 Views
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Article
cIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation
Rosanna Lau, Min Ying Niu & M.A. Christine Pratt
Pages: 4009-4019
Published online: 03 Oct 2012
AbstractforcIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation | Full Text | References | PDF (2 MB) | Supplemental
  • 1089 Views
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Article
Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin)
Cristina Oliveras-Ferraros, Bruna Corominas-Faja, Sílvia Cufí, Alejandro Vazquez-Martin, Begoña Martin-Castillo, Juan Manuel Iglesias, Eugeni López-Bonet, Ángel G. Martin & Javier A. Menendez
Pages: 4020-4032
Published online: 19 Sep 2012
AbstractforEpithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin) | Full Text | References | PDF (2.5 MB)
  • 2108 Views
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Article
p53 mutation alters the effect of the esophageal tumor suppressor KLF5 on keratinocyte proliferation
Yizeng Yang, Rohinton S. Tarapore, Melissa H. Jarmel, Marie-Pier Tetreault & Jonathan P. Katz
Pages: 4033-4039
Published online: 18 Sep 2012
Abstractforp53 mutation alters the effect of the esophageal tumor suppressor KLF5 on keratinocyte proliferation | Full Text | References | PDF (1.9 MB) | Supplemental
  • 911 Views
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Article
CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD
Nikolay O. Bukanov, Sarah E. Moreno, Thomas A. Natoli, Kelly A. Rogers, Laurie A. Smith, Steven R. Ledbetter, Nassima Oumata, Hervé Galons, Laurent Meijer & Oxana Ibraghimov-Beskrovnaya
Pages: 4040-4046
Published online: 03 Oct 2012
AbstractforCDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD | Full Text | References | PDF (1.2 MB)
  • 1370 Views
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Article
B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1)
Eugen Werwein, Thore Schmedt, Heiko Hoffmann, Clemens Usadel, Nora Obermann, Jeffrey D. Singer & Karl-Heinz Klempnauer
Pages: 4047-4058
Published online: 03 Oct 2012
AbstractforB-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1) | Full Text | References | PDF (1.6 MB) | Supplemental
  • 805 Views
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Article
FBXW7 is involved in Aurora B degradation
Chieh-Lin Teng, Yun-Chi Hsieh, Liem Phan, Jihyun Shin, Chris Gully, Guermarie Velazquez-Torres, Stephen Skerl, Sai-Ching J. Yeung, Shih-Lan Hsu & Mong-Hong Lee
Pages: 4059-4068
Published online: 24 Oct 2012
AbstractforFBXW7 is involved in Aurora B degradation | Full Text | References | PDF (2.4 MB)
  • 1253 Views
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Article
The PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells
Monika Kusio-Kobialka, Paulina Podszywalow-Bartnicka, Philippos Peidis, Eliza Glodkowska-Mrowka, Kamila Wolanin, Grzegorz Leszak, Ilona Seferynska, Tomasz Stoklosa, Antonis E. Koromilas & Katarzyna Piwocka
Pages: 4069-4078
Published online: 24 Oct 2012
AbstractforThe PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells | Full Text | References | PDF (1.5 MB)
  • 1449 Views
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Article
Erlotinib antagonizes ABC transporters in acute myeloid leukemia
Elodie Lainey, Marie Sébert, Sylvain Thépot, Marie Scoazec, Cyrielle Bouteloup, Carole Leroy, Stéphane De Botton, Lorenzo Galluzzi, Pierre Fenaux & Guido Kroemer
Pages: 4079-4092
Published online: 24 Oct 2012
AbstractforErlotinib antagonizes ABC transporters in acute myeloid leukemia | Full Text | References | PDF (5.5 MB) | Supplemental
  • 1120 Views
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Letter to the Editor

Letter
Level of cdk5 expression predicts the survival of relapsed multiple myeloma patients
Zachary Levacque, Jesusa L. Rosales & Ki-Young Lee
Pages: 4093-4095
Published online: 17 Sep 2012
First Page PreviewforLevel of cdk5 expression predicts the survival of relapsed multiple myeloma patients | PDF (719.3 KB)
  • 343 Views
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