Cell Cycle, Volume 11, Issue 4 (2012)

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Cell Cycle, Volume 11, Issue 4 (2012)

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Editorials: Cell Cycle Features

Editorial
Critical role of mTOR in calcineurin inhibitor-induced renal cancer progression
Aninda Basu, Pallavi Banerjee & Soumitro Pal
Pages: 633-634
Published online: 15 Feb 2012
AbstractforCritical role of mTOR in calcineurin inhibitor-induced renal cancer progression | Full Text | References | PDF (218.6 KB)
  • 405 Views
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Editorial
Trans mechanism for ubiquitin-like protein transfer in autophagy
Asad M. Taherbhoy, Stephen E. Kaiser & Brenda A. Schulman
Pages: 635-636
Published online: 15 Feb 2012
AbstractforTrans mechanism for ubiquitin-like protein transfer in autophagy | PDF (399.7 KB)
  • 224 Views
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Editorial
A TORway to osteolytic disease
Achim Leutz & Jeske Smink
Pages: 637-638
Published online: 15 Feb 2012
AbstractforA TORway to osteolytic disease | PDF (484.6 KB)
  • 144 Views
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Editorial
Emerging targets for the prevention of pregnancy-associated breast cancer
Jaime Fornetti, Holly Martinson, Virginia Borges & Pepper Schedin
Pages: 639-640
Published online: 15 Feb 2012
AbstractforEmerging targets for the prevention of pregnancy-associated breast cancer | Full Text | References | PDF (605.8 KB)
  • 574 Views
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Open Access
Editorial
Sumoylation fights “aggregopathies”
Petranka Krumova & Jochen H. Weishaupt
Pages: 641-642
Published online: 15 Feb 2012
AbstractforSumoylation fights “aggregopathies” | PDF (168.3 KB)
  • 461 Views
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Editorial
The aryl hydrocarbon receptor as a promoter of malignant glioma
Michael Platten, Christiane Opitz & Wolfgang Wick
Pages: 643-644
Published online: 15 Feb 2012
AbstractforThe aryl hydrocarbon receptor as a promoter of malignant glioma | PDF (272.2 KB)
  • 325 Views
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Cell Cycle News & Views

Micronucleophagy: A new mechanism to protect against chromosomal instability?
Patricia Boya & Patrice Codogno
Page: 645
Published online: 15 Feb 2012
AbstractforMicronucleophagy: A new mechanism to protect against chromosomal instability? | PDF (628.6 KB)
  • 408 Views
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Open Access
All p65-containing dimers are not equal
Simona Saccani
Page: 646
Published online: 15 Feb 2012
AbstractforAll p65-containing dimers are not equal | PDF (614.7 KB)
  • 189 Views
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TRPV1 antagonists may exacerbate sepsis in aged mice: Should we be nervous?
Zenaide M. Quezado & Arpad Szallasi
Page: 647
Published online: 15 Feb 2012
AbstractforTRPV1 antagonists may exacerbate sepsis in aged mice: Should we be nervous? | PDF (614.7 KB)
  • 176 Views
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Open Access
TRIM8 and p53: Making the right decision
Elisabetta Botti, Giulia Spallone & Antonio Costanzo
Page: 648
Published online: 15 Feb 2012
AbstractforTRIM8 and p53: Making the right decision | PDF (614.7 KB)
  • 281 Views
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Open Access
Article Commentary
Sgo1 as a “guardian spirit” for preventing colon tumorigenesis
Robin M. Ricke & Jan M. van Deursen
Page: 649
Published online: 15 Feb 2012
First Page PreviewforSgo1 as a “guardian spirit” for preventing colon tumorigenesis | Full Text | References | PDF (614.7 KB)
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Sgo1 as a guardian of chromosome stability
Laura A. Díaz-Martínez & Hongtao Yu
Pages: 650-651
Published online: 15 Feb 2012
AbstractforSgo1 as a guardian of chromosome stability | PDF (614.7 KB)
  • 249 Views
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Extra Views

RPA and POT1
Friends or foes at telomeres?
Rachel Litman Flynn, Sandy Chang & Lee Zou
Pages: 652-657
Published online: 15 Feb 2012
AbstractforRPA and POT1 | Full Text | References | PDF (762.5 KB)
  • 1594 Views
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New insights into replication origin characteristics in metazoans
Christelle Cayrou, Philippe Coulombe, Aurore Puy, Stephanie Rialle, Noam Kaplan, Eran Segal & Marcel Méchali
Pages: 658-667
Published online: 15 Feb 2012
AbstractforNew insights into replication origin characteristics in metazoans | Full Text | References | PDF (1.7 MB)
  • 1885 Views
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Open Access
NER and DDR: Classical music with new instruments
Sarah Sertic, Sara Pizzi, Federico Lazzaro, Paolo Plevani & Marco Muzi-Falconi
Pages: 668-674
Published online: 15 Feb 2012
AbstractforNER and DDR: Classical music with new instruments | PDF (920.4 KB)
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Dynamic expression of the Robo ligand Slit2 in bone marrow cell populations
Stephanie Smith-Berdan, Koen Schepers, Alan Ly, Emmanuelle Passegué & E. Camilla Forsberg
Pages: 675-682
Published online: 15 Feb 2012
AbstractforDynamic expression of the Robo ligand Slit2 in bone marrow cell populations | PDF (2 MB)
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Perspective

The emerging role of the TGFβ tumor suppressor pathway in pancreatic cancer
David J. Birnbaum, Emilie Mamessier & Daniel Birnbaum
Pages: 683-686
Published online: 15 Feb 2012
AbstractforThe emerging role of the TGFβ tumor suppressor pathway in pancreatic cancer | PDF (696.5 KB)
  • 494 Views
  • 10 CrossRef citations
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BRCA1-directed, enhanced and aberrant homologous recombination
Mechanism and potential treatment strategies
Seth M. Dever, E. Railey White, Matthew C.T. Hartman & Kristoffer Valerie
Pages: 687-694
Published online: 15 Feb 2012
AbstractforBRCA1-directed, enhanced and aberrant homologous recombination | Full Text | References | PDF (1.2 MB)
  • 735 Views
  • 18 CrossRef citations
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Report

Article
Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration
Shuyuan Chen, Masayuki Shimoda, Jiaxi Chen, Shinichi Matsumoto & Paul A. Grayburn
Pages: 695-705
Published online: 15 Feb 2012
AbstractforTransient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration | Full Text | References | PDF (26.9 MB)
  • 795 Views
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Article
ApoA1
Mimetic peptide reverses adipocyte dysfunction in vivo and in vitro via an increase in heme oxygenase (HO-1) and Wnt10b
Luca Vanella, Ming Li, DongHyun Kim, Giuseppe Malfa, Lars Bellner, Tomoko Kawakami & Nader G. Abraham
Pages: 706-714
Published online: 15 Feb 2012
AbstractforApoA1 | Full Text | References | PDF (1.9 MB)
  • 903 Views
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Article
EDD induces cell cycle arrest by increasing p53 levels
Veronique A.J. Smits
Pages: 715-720
Published online: 15 Feb 2012
AbstractforEDD induces cell cycle arrest by increasing p53 levels | PDF (1.6 MB)
  • 815 Views
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Article
Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest
Tiffany A. Coon, Jennifer R. Glasser, Rama K. Mallampalli & Bill B. Chen
Pages: 721-729
Published online: 15 Feb 2012
AbstractforNovel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest | Full Text | References | PDF (2.4 MB)
  • 1255 Views
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Article
The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts
Hirotada Kojima, Hiroyuki Kunimoto, Toshiaki Inoue & Koichi Nakajima
Pages: 730-739
Published online: 15 Feb 2012
AbstractforThe STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts | PDF (971 KB) | Supplemental
  • 1527 Views
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Article
Expression profiles of cohesins, shugoshins and spindle assembly checkpoint genes in rhesus macaque oocytes predict their susceptibility for aneuploidy during embryonic development
Catherine Dupont, Alexandra J. Harvey, D. Randall Armant, Mary B. Zelinski & Carol A. Brenner
Pages: 740-748
Published online: 15 Feb 2012
AbstractforExpression profiles of cohesins, shugoshins and spindle assembly checkpoint genes in rhesus macaque oocytes predict their susceptibility for aneuploidy during embryonic development | Full Text | References | PDF (736.3 KB) | Supplemental
  • 639 Views
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Article
MDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage
Giusy Di Conza, Francesca Mancini, Marianna Buttarelli, Alfredo Pontecorvi, Francesco Trimarchi & Fabiola Moretti
Pages: 749-760
Published online: 15 Feb 2012
AbstractforMDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage | PDF (1.3 MB)
  • 498 Views
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Article
Mimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells
Soon-Young Park, Jun-Sub Im, Sung-Rye Park, Sang-Eun Kim, Hoe-Jeong Wang & Joon-Kyu Lee
Pages: 761-766
Published online: 15 Feb 2012
AbstractforMimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells | PDF (615.5 KB)
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Article
MicroRNA-143 is a critical regulator of cell cycle activity in stem cells with co-overexpression of Akt and angiopoietin-1 via transcriptional regulation of Erk5/cyclin D1 signaling
Vien Khach Lai, Muhammad Ashraf, Shujia Jiang & Khawaja Haider
Pages: 767-777
Published online: 15 Feb 2012
AbstractforMicroRNA-143 is a critical regulator of cell cycle activity in stem cells with co-overexpression of Akt and angiopoietin-1 via transcriptional regulation of Erk5/cyclin D1 signaling | Full Text | References | PDF (6.5 MB) | Supplemental
  • 794 Views
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Article
Inactivation of Pmc1 vacuolar Ca2+ ATPase causes G2 cell cycle delay in Hansenula polymorpha
Anastasia Fokina, Svyatoslav Sokolov, Hyun Ah Kang, Michael D. Ter-Avanesyan & Michael Agaphonov
Pages: 778-784
Published online: 15 Feb 2012
AbstractforInactivation of Pmc1 vacuolar Ca2+ ATPase causes G2 cell cycle delay in Hansenula polymorpha | PDF (763.4 KB)
  • 443 Views
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Article
MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN
Changju Qu, Zhihui Liang, JiaLing Huang, Ruiying Zhao, Chunhui Su, Sumei Wang, Xudan Wang, Rong Zhang, Mong-Hong Lee & Huiling Yang
Pages: 785-796
Published online: 15 Feb 2012
AbstractforMiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN | Full Text | References | PDF (6 MB)
  • 1462 Views
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Article
Sumoylated BubR1 plays an important role in chromosome segregation and mitotic timing
Feikun Yang, Ying Huang & Wei Dai
Pages: 797-806
Published online: 15 Feb 2012
AbstractforSumoylated BubR1 plays an important role in chromosome segregation and mitotic timing | Full Text | References | PDF (2.9 MB) | Supplemental
  • 724 Views
  • 19 CrossRef citations
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Article
The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent
Jayasree S. Nair, Alan L. Ho & Gary K. Schwartz
Pages: 807-817
Published online: 15 Feb 2012
AbstractforThe induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent | Full Text | References | PDF (2.1 MB) | Supplemental
  • 1162 Views
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Article
Synaptotagmin1 is required for spindle stability and metaphase-to-anaphase transition in mouse oocytes
Xiu-Lan Zhu, Shu-Tao Qi, Jun Liu, Lei Chen, Chunhui Zhang, Shang-Wu Yang, Ying-Chun Ouyang, Yi Hou, Heide Schatten, Ya-Li Song, Fu-Qi Xing & Qing-Yuan Sun
Pages: 818-826
Published online: 15 Feb 2012
AbstractforSynaptotagmin1 is required for spindle stability and metaphase-to-anaphase transition in mouse oocytes | PDF (1.9 MB) | Supplemental
  • 619 Views
  • 8 CrossRef citations
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