Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 25, Issue 1 (2010)

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Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 25, Issue 1 (2010)

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Research Article

Article
Fluorobenzoyl dipeptidyl derivatives as inhibitors of the Fasciola hepatica cysteine protease cathepsin L1
Brian W. Moran, Frankie P. Anderson, Deborah M. Ruth, Ciarán Ó. Fágáin, John P. Dalton & Peter T. M. Kenny
Pages: 1-12
Published online: 23 Dec 2009
AbstractforFluorobenzoyl dipeptidyl derivatives as inhibitors of the Fasciola hepatica cysteine protease cathepsin L1 | Full Text | References | PDF (905.9 KB)
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Article
Stereoselective inhibition of butyrylcholinesterase by enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates
Shyh-Ying Chiou, Chun-Fu Huang, Shih-Jei Yeh, I-Ru Chen & Gialih Lin
Pages: 13-20
Published online: 23 Dec 2009
AbstractforStereoselective inhibition of butyrylcholinesterase by enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates | Full Text | References | PDF (1,010.8 KB)
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Article
Antibacterial and antifungal studies of macrocyclic complexes of trivalent transition metal ions with their spectroscopic approach
D. P. Singh, Krishan Kumar, Saurabh Sudha Dhiman & Jitender Sharma
Pages: 21-28
Published online: 23 Dec 2009
AbstractforAntibacterial and antifungal studies of macrocyclic complexes of trivalent transition metal ions with their spectroscopic approach | Full Text | References | PDF (1.2 MB)
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Article
Synthesis and leishmanicidal activity of 2,3,4-substituted-5-imidazolones
Khalid Mohammed Khan, Uzma Rasool Mughal, Nida Ambreen, Samreen, Shahnaz Perveen & M. Iqbal Choudhary
Pages: 29-37
Published online: 23 Dec 2009
AbstractforSynthesis and leishmanicidal activity of 2,3,4-substituted-5-imidazolones | Full Text | References | PDF (763 KB)
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Article
Design, synthesis, and biological evaluation of 3,4,5-trimethoxyphenyl acrylamides as antinarcotic agents
Jae-Chul Jung, Dongguk Min, Heejeong Kim, Soyong Jang, Yongnam Lee, WooKyu Park, Ikhlas A. Khan, Hyung-In Moon, Mankil Jung & Seikwan Oh
Pages: 38-43
Published online: 23 Dec 2009
AbstractforDesign, synthesis, and biological evaluation of 3,4,5-trimethoxyphenyl acrylamides as antinarcotic agents | Full Text | References | PDF (760.9 KB)
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Article
Antioxidant activity of bisbenzylisoquinoline alkaloids from Stephania rotunda: cepharanthine and fangchinoline
İlhami Gülçin, Riad Elias, Akçahan Gepdiremen, Aun Chea & Fevzi Topal
Pages: 44-53
Published online: 23 Dec 2009
AbstractforAntioxidant activity of bisbenzylisoquinoline alkaloids from Stephania rotunda: cepharanthine and fangchinoline | Full Text | References | PDF (999.9 KB)
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Article
Antimicrobial activities of some synthetic butenolides and their pyrrolone derivatives
Asif Husain, Mohammed Mumtaz Alam, Mohammed Shaharyar & Sukhbir Lal
Pages: 54-61
Published online: 23 Dec 2009
AbstractforAntimicrobial activities of some synthetic butenolides and their pyrrolone derivatives | Full Text | References | PDF (716.3 KB)
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Article
Cruzain inhibition by hydroxymethylnitrofurazone and nitrofurazone: investigation of a new target in Trypanosoma cruzi
Gustavo H. G. Trossini, Alberto Malvezzi, Antonia T.-do Amaral, Carlota Oliveira Rangel-Yagui, Mario A. Izidoro, Maria Helena S. Cezari, Luiz Juliano, Chung Man Chin, Carla M. S. Menezes & Elizabeth Igne Ferreira
Pages: 62-67
Published online: 23 Dec 2009
AbstractforCruzain inhibition by hydroxymethylnitrofurazone and nitrofurazone: investigation of a new target in Trypanosoma cruzi | Full Text | References | PDF (852.3 KB)
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Article
Inhibition of purified bovine liver glutathione reductase with some metal ions
Berivan Tandogan & N. Nuray Ulusu
Pages: 68-73
Published online: 29 Oct 2009
AbstractforInhibition of purified bovine liver glutathione reductase with some metal ions | Full Text | References | PDF (987.8 KB)
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Article
Synthesis of some imidazolyl-thioacetyl-pyrazolinone derivatives and their antinociceptive and anticancer activities
Seref Demirayak, Ismail Kayagil, Leyla Yurttas & Rana Aslan
Pages: 74-79
Published online: 23 Dec 2009
AbstractforSynthesis of some imidazolyl-thioacetyl-pyrazolinone derivatives and their antinociceptive and anticancer activities | Full Text | References | PDF (664.7 KB)
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Article
New antihyperglycemic, α-glucosidase inhibitory, and cytotoxic derivatives of benzimidazoles
Jaladi Ashok Kumar, Ashok Kumar Tiwari, Amtul Zehra Ali, Kuncha Madhusudhana, Boreddy Srinivas Reddy, Sistala Ramakrishna & Bhimapaka China Raju
Pages: 80-86
Published online: 23 Dec 2009
AbstractforNew antihyperglycemic, α-glucosidase inhibitory, and cytotoxic derivatives of benzimidazoles | Full Text | References | PDF (765.3 KB)
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Article
DNA cleavage and in vitro antimicrobial studies of Co(II), Ni(II), and Cu(II) complexes with ONNO donor Schiff bases: Synthesis, spectral characterization, and electrochemical studies
Ajaykumar Kulkarni, Sangamesh A. Patil & Prema S. Badami
Pages: 87-96
Published online: 23 Dec 2009
AbstractforDNA cleavage and in vitro antimicrobial studies of Co(II), Ni(II), and Cu(II) complexes with ONNO donor Schiff bases: Synthesis, spectral characterization, and electrochemical studies | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Metabolite profile and in vitro activities of Phagnalon saxatile (L.) Cass. relevant to treatment of Alzheimer’s disease
Filomena Conforti, Daniela Rigano, Carmen Formisano, Maurizio Bruno, Monica Rosa Loizzo, Francesco Menichini & Felice Senatore
Pages: 97-104
Published online: 23 Dec 2009
AbstractforMetabolite profile and in vitro activities of Phagnalon saxatile (L.) Cass. relevant to treatment of Alzheimer’s disease | Full Text | References | PDF (659.5 KB)
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Article
5-Nitrothiazolylthiosemicarbazones: Synthesis and antimycobacterial evaluation against tubercular and non-tubercular mycobacterial species
Dhrmarajan Sriram, Perumal Yogeeswari, Palaniappan Senthilkumar & Dewakar Sangaraju
Pages: 105-110
Published online: 25 Nov 2009
Abstractfor5-Nitrothiazolylthiosemicarbazones: Synthesis and antimycobacterial evaluation against tubercular and non-tubercular mycobacterial species | Full Text | References | PDF (615.3 KB)
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Article
Trypanocidal activity of the ethyl esters of N-propyl and N-isopropyl oxamates on intracellular amastigotes of Trypanosoma cruzi acute infected mice
Charmina Aguirre-Alvarado, Fabiola Zaragoza-Martínez, Lorena Rodríguez-Páez, Juan Luis Téllez-Rendón, Benjamín Nogueda, Isabel Baeza & Carlos Wong
Pages: 111-115
Published online: 23 Dec 2009
AbstractforTrypanocidal activity of the ethyl esters of N-propyl and N-isopropyl oxamates on intracellular amastigotes of Trypanosoma cruzi acute infected mice | Full Text | References | PDF (853.3 KB)
  • 387 Views
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Article
Inactivation of acetylcholinesterase by various fluorophores
Lilu Guo, Alirica I. Suarez & Charles M. Thompson
Pages: 116-120
Published online: 20 Oct 2009
AbstractforInactivation of acetylcholinesterase by various fluorophores | Full Text | References | PDF (705.9 KB)
  • 443 Views
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Article
Synthesis and antimicrobial studies of s-triazine based heterocycles
Dharmendra H. Patel, Kishor H. Chikhalia, Nisha K. Shah, Dhaval P. Patel, Pankaj B. Kaswala & Vipul M. Buha
Pages: 121-125
Published online: 08 Oct 2009
AbstractforSynthesis and antimicrobial studies of s-triazine based heterocycles | Full Text | References | PDF (580.1 KB)
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Article
Synthesis, structure, and antifungal evaluation of some novel 1,2,4-triazolylmercaptoacetylthiosemicarbazide and 1,2,4-triazolylmercaptomethyl-1,3,4-thiadiazole analogs
Nalan Terzioğlu Klip, Gültaze Çapan, Aysel Gürsoy, Meltem Uzun & Dilek Satana
Pages: 126-131
Published online: 23 Dec 2009
AbstractforSynthesis, structure, and antifungal evaluation of some novel 1,2,4-triazolylmercaptoacetylthiosemicarbazide and 1,2,4-triazolylmercaptomethyl-1,3,4-thiadiazole analogs | Full Text | References | PDF (675.8 KB)
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Article
Synthesis of a novel series of benzylether-containing cinnamoyl derivatives as histone deacetylase inhibitors
Jie Jiao, Hao Fang, Xuejian Wang, Huawei Zhu, Lan Jiang & Wenfang Xu
Pages: 132-138
Published online: 23 Dec 2009
AbstractforSynthesis of a novel series of benzylether-containing cinnamoyl derivatives as histone deacetylase inhibitors | Full Text | References | PDF (969 KB)
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Short Communication

Article
Synthesis and activity of amides of tripeptides as potential urokinase inhibitors
Agnieszka Markowska, Irena Bruzgo & Krystyna Midura-Nowaczek
Pages: 139-142
Published online: 23 Dec 2009
AbstractforSynthesis and activity of amides of tripeptides as potential urokinase inhibitors | Full Text | References | PDF (615.8 KB)
  • 497 Views
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Article
New antioxidant flavonoid isolated from Leuzea carthamoides
Vit Koleckar, Lubomir Opletal, Katerina Macakova, Ludek Jahodar, Daniel Jun, Jiri Kunes & Kamil Kuca
Pages: 143-145
Published online: 23 Dec 2009
AbstractforNew antioxidant flavonoid isolated from Leuzea carthamoides | Full Text | References | PDF (629.6 KB)
  • 798 Views
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Differential inhibition of homotrimeric dUTPases by the 3′azido derivative of dideoxy-UTP
Lorena Gonzalez Palmén & Jan-Olov Kvassman
Pages: 146-150
Published online: 23 Dec 2009
AbstractforDifferential inhibition of homotrimeric dUTPases by the 3′azido derivative of dideoxy-UTP | Full Text | References | PDF (875.1 KB)
  • 402 Views
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