Cancer Biology & Therapy, Volume 19, Issue 12 (2018)

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Cancer Biology & Therapy, Volume 19, Issue 12 (2018)

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Letter to the Editor

Letter to the Editor
Great efficacy of bevacizumab plus erlotinib for leptomeningeal metastases from non-small cell lung cancer with initially positive EGFR mutation: a case report
Wang Jing, Haiyong Wang, Li Kong, Jinming Yu & Hui Zhu
Pages: 1073-1077
Published online: 01 Aug 2018
AbstractforGreat efficacy of bevacizumab plus erlotinib for leptomeningeal metastases from non-small cell lung cancer with initially positive EGFR mutation: a case report | Full Text | References | PDF (792.7 KB)
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Bedside to Bench Report

Report
Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer
Maria Tsoli, Carol Wadham, Mark Pinese, Tim Failes, Swapna Joshi, Emily Mould, Julia X. Yin, Velimir Gayevskiy, Amit Kumar, Warren Kaplan, Paul G. Ekert, Federica Saletta, Laura Franshaw, Jie Liu, Andrew Gifford, Martin A. Weber, Michael Rodriguez, Richard J. Cohn, Greg Arndt, Vanessa Tyrrell, Michelle Haber, Toby Trahair, Glenn M. Marshall, Kerrie McDonald, Mark J. Cowley & David S. Ziegler
Pages: 1078-1087
Published online: 09 Oct 2018
AbstractforIntegration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer | Full Text | References | PDF (2 MB)
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Report
Successful maintenance therapy with apatinib inplatinum-resistant advanced ovarian cancer and literature review
Min Jin, Jun Cai, Xuan Wang, Tao Zhang & Yingchao Zhao
Pages: 1088-1092
Published online: 15 Aug 2018
AbstractforSuccessful maintenance therapy with apatinib inplatinum-resistant advanced ovarian cancer and literature review | Full Text | References | PDF (731.5 KB)
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Report
Successful treatment using apatinib in intractable brain edema: A case report and literatures review
Yanqiu Song MD, PhD, Bailong Liu MD, PhD, Meng Guan Master of Medicine & Min Liu
Pages: 1093-1096
Published online: 06 Aug 2018
AbstractforSuccessful treatment using apatinib in intractable brain edema: A case report and literatures review | Full Text | References | PDF (809.8 KB)
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Report
A novel co-existing ZCCHC8-ROS1 and de-novo MET amplification dual driver in advanced lung adenocarcinoma with a good response to crizotinib
You-cai Zhu, Wen-xian Wang, Chun-wei Xu, Wu Zhuang, Zheng-bo Song, Kai-qi Du, Gang Chen, Tang-feng Lv & Yong Song
Pages: 1097-1101
Published online: 10 Aug 2018
AbstractforA novel co-existing ZCCHC8-ROS1 and de-novo MET amplification dual driver in advanced lung adenocarcinoma with a good response to crizotinib | Full Text | References | PDF (862.3 KB)
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CLINICAL STUDY

Case Report
Comparing treatment outcomes of concurrent chemoradiotherapy with or without nimotuzumab in patients with locoregionally advanced nasopharyngeal carcinoma
Ji-Jin Yao, Lu-Lu Zhang, Tian-Sheng Gao, Ying-Lin Peng, Wayne R. Lawrence, Wang-Jian Zhang, Fan Zhang, Guan-Qun Zhou, Si-Yang Wang & Ying Sun
Pages: 1102-1107
Published online: 06 Aug 2018
AbstractforComparing treatment outcomes of concurrent chemoradiotherapy with or without nimotuzumab in patients with locoregionally advanced nasopharyngeal carcinoma | Full Text | References | PDF (740.7 KB)
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Clinical Study

Case Report
FGFR genes mutation is an independent prognostic factor and associated with lymph node metastasis in squamous non-small cell lung cancer
Jing Jing Li, Shi Yan, Yaqi Pan, Zhen Liu, Ying Liu, Qiuju Deng, Qin Tan, Emma R. Woodward & Nan Wu
Pages: 1108-1116
Published online: 07 Nov 2018
AbstractforFGFR genes mutation is an independent prognostic factor and associated with lymph node metastasis in squamous non-small cell lung cancer | Full Text | References | PDF (1.2 MB)
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Research Paper

Article
Circ0043898 acts as a tumor inhibitor and performs regulatory effect on the inhibition of esophageal carcinoma
Wei Wang, Jun Ma, Jianjun Lu, Danqing Fang, Xinming Xiong, Xin Yang & Tingting Xie
Pages: 1117-1127
Published online: 25 Sep 2018
AbstractforCirc0043898 acts as a tumor inhibitor and performs regulatory effect on the inhibition of esophageal carcinoma | Full Text | References | PDF (2.4 MB)
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Article
RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway
Yalan Lu, Deqiang Han, Wenjie Liu, Rong Huang, Jinhuan Ou, Xiaoqiao Chen, Xizhe Zhang, Xuezhi Wang, Shijun Li, Lin Wang, Changzheng Liu, Shiying Miao, Linfang Wang, Changwu Ma & Wei Song
Pages: 1128-1138
Published online: 27 Sep 2018
AbstractforRNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway | Full Text | References | PDF (5.2 MB)
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Article
Emerging roles of circRNA_NEK6 targeting miR-370-3p in the proliferation and invasion of thyroid cancer via Wnt signaling pathway
Fukun Chen, Zhiping Feng, Jialun Zhu, Pengjie Liu, Chuanzhou Yang, Rongkai Huang & Zhiyong Deng
Pages: 1139-1152
Published online: 12 Sep 2018
AbstractforEmerging roles of circRNA_NEK6 targeting miR-370-3p in the proliferation and invasion of thyroid cancer via Wnt signaling pathway | Full Text | References | PDF (3.2 MB)
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Article
Antidiabetic drugs influence molecular mechanisms in prostate cancer
Andreas Pircher, Martin Zieher, Andrea Eigentler, Renate Pichler, Georg Schäfer, Josef Fritz, Martin Puhr, Eberhard Steiner, Wolfgang Horninger, Helmut Klocker & Isabel Heidegger
Pages: 1153-1161
Published online: 01 Aug 2018
AbstractforAntidiabetic drugs influence molecular mechanisms in prostate cancer | Full Text | References | PDF (969.1 KB)
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Article
Upregulation of microRNA-129-5p inhibits cell invasion, migration and tumor angiogenesis by inhibiting ZIC2 via downregulation of the Hedgehog signaling pathway in cervical cancer
Ying-Fang Wang, Hong-Yun Yang, Xiao-Qin Shi & Yue Wang
Pages: 1162-1173
Published online: 27 Sep 2018
AbstractforUpregulation of microRNA-129-5p inhibits cell invasion, migration and tumor angiogenesis by inhibiting ZIC2 via downregulation of the Hedgehog signaling pathway in cervical cancer | Full Text | References | PDF (1.7 MB)
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Article
The role of JNK phosphorylation as a molecular target to enhance adenovirus replication, oncolysis and cancer therapeutic efficacy
Stephen L. Wechman, Xiao-Mei Rao, Jorge G. Gomez-Gutierrez, Heshan Sam Zhou & Kelly M. McMasters
Pages: 1174-1184
Published online: 01 Aug 2018
AbstractforThe role of JNK phosphorylation as a molecular target to enhance adenovirus replication, oncolysis and cancer therapeutic efficacy | Full Text | References | PDF (2 MB)
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Article
MicroRNA-886-3P functions as a tumor suppressor in small cell lung cancer
Jie Shen, Wei Zhou, Nan Bi, Yong-Mei Song, Fu-Quan Zhang, Qi-Min Zhan & Lv-Hua Wang
Pages: 1185-1192
Published online: 19 Sep 2018
AbstractforMicroRNA-886-3P functions as a tumor suppressor in small cell lung cancer | Full Text | References | PDF (1.6 MB)
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Article
CRMP4a suppresses cell motility by sequestering RhoA activity in prostate cancer cells
Changlin Li, Haixia Xu, Lin Xiao, Haizhou Zhu, Guoan Zhang, Wei Wei, Kaizhi Li, Xiande Cao, Daqing Shen, Jeffrey Holzbeierlein & Benyi Li
Pages: 1193-1203
Published online: 06 Aug 2018
AbstractforCRMP4a suppresses cell motility by sequestering RhoA activity in prostate cancer cells | Full Text | References | PDF (2.2 MB)
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