Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 25, Issue 6 (2010)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 25, Issue 6 (2010)

See all volumes and issues
Vol 39, 2024 Vol 38, 2023 Vol 37, 2022 Vol 36, 2021 Vol 35, 2020 Vol 34, 2019 Vol 33, 2018 Vol 32, 2017 Vol 31, 2016 Vol 30, 2015 Vol 29, 2014 Vol 28, 2013 Vol 27, 2012 Vol 26, 2011 Volume 25, 2010 Vol 24, 2009 Vol 23, 2008 Vol 22, 2007 Vol 21, 2006 Vol 20, 2005 Vol 19, 2004 Vol 18, 2003 Vol 17, 2002 Vol 16, 2001 Vol 15, 1999-2000 Vol 14, 1998-1999 Vol 13, 1998 Vol 12, 1997 Vol 11, 1996-1997 Vol 10, 1995-1996 Vol 9, 1995 Vol 8, 1994-1995 Vol 7, 1993 Vol 6, 1992-1993 Vol 5, 1991 Vol 4, 1990-1991 Vol 3, 1989-1990 Vol 2, 1987-1989 Vol 1, 1985-1987
Download citations Download PDFs Download issue

Original Article

Article
The hypolipidemic activity of novel benzofuran-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats: a comparison with bezafibrate
Ghassan Shattat, Tariq Al-Qirim, Kamal Sweidan, Moyad Shahwan, Waseem El-Huneidi & Yusuf Al-Hiari
Pages: 751-755
Published online: 30 Jun 2010
AbstractforThe hypolipidemic activity of novel benzofuran-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats: a comparison with bezafibrate | Full Text | References | PDF (729.5 KB)
  • 933 Views
  • 19 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis, spectral characterization, and in vitro antibacterial and antifungal activities of novel 1,3-thiazine-2-amines comprising morpholine nucleus
J. Thanusu, V. Kanagarajan & M. Gopalakrishnan
Pages: 756-764
Published online: 30 Jun 2010
AbstractforSynthesis, spectral characterization, and in vitro antibacterial and antifungal activities of novel 1,3-thiazine-2-amines comprising morpholine nucleus | Full Text | References | PDF (766.9 KB)
  • 740 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access
Article
5-Nitro-2,6-dioxohexahydro-4-pyrimidinecarboxamides: synthesis, in vitro antimycobacterial activity, cytotoxicity, and isocitrate lyase inhibition studies
Dharmarajan Sriram, Perumal Yogeeswari, Palaniappan Senthilkumar, Geetanjali Naidu & Pritesh Bhat
Pages: 765-772
Published online: 23 Jun 2010
Abstractfor5-Nitro-2,6-dioxohexahydro-4-pyrimidinecarboxamides: synthesis, in vitro antimycobacterial activity, cytotoxicity, and isocitrate lyase inhibition studies | Full Text | References | PDF (1,004.7 KB)
  • 633 Views
  • 12 CrossRef citations
  • 0Altmetric
Free Access
Article
Two new anti-plasmodial flavonoid glycosides from Duranta repens
Fozia Ijaz, Nisar Ahmad, Ijaz Ahmad, Azhar ul Haq & Fanghai Wang
Pages: 773-778
Published online: 22 Jun 2010
AbstractforTwo new anti-plasmodial flavonoid glycosides from Duranta repens | Full Text | References | PDF (648.5 KB)
  • 960 Views
  • 15 CrossRef citations
  • 0Altmetric
Free Access
Article
Interactions of melatonin and serotonin with lactoperoxidase enzyme
Melda Şişecioğlu, Murat Çankaya, İlhami Gülçin & Hasan Özdemir
Pages: 779-783
Published online: 02 Feb 2010
AbstractforInteractions of melatonin and serotonin with lactoperoxidase enzyme | Full Text | References | PDF (817.9 KB)
  • 1118 Views
  • 49 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis and antidiabetic activity of some new chromonyl-2,4-thiazolidinediones
Meltem Ceylan-Ünlüsoy, Eugen J. Verspohl & Rahmiye Ertan
Pages: 784-789
Published online: 05 Aug 2010
AbstractforSynthesis and antidiabetic activity of some new chromonyl-2,4-thiazolidinediones | Full Text | References | PDF (616.2 KB)
  • 1010 Views
  • 22 CrossRef citations
  • 0Altmetric
Free Access
Article
A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques
Jiri Bajgar, Petr Hajek, Jana Karasova Zdarova, Jiri Kassa, Antonin Paseka, Dasa Slizova, Otakar Krs, Kamil Kuca, Daniel Jun, Josef Fusek & Lukas Capek
Pages: 790-797
Published online: 08 Nov 2010
AbstractforA comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques | Full Text | References | PDF (1.2 MB)
  • 532 Views
  • 5 CrossRef citations
  • 0Altmetric
Free Access
Article
Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities
Yu-Jing Zhu, Ling Qiu, Jing-Jing Zhou, Hua-Yun Guo, Yong-Hua Hu, Zhi-Cong Li, Qin Wang, Qing-Xi Chen & Bo Liu
Pages: 798-803
Published online: 28 Jun 2010
AbstractforInhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities | Full Text | References | PDF (988.7 KB)
  • 1604 Views
  • 29 CrossRef citations
  • 0Altmetric
Free Access
Article
Tyrosine and glycine derivatives as potential prodrugs: design, synthesis, and pharmacological evaluation of amide derivatives of mefenamic acid
Arun Rasheed & C. K. Ashok Kumar
Pages: 804-811
Published online: 28 Jun 2010
AbstractforTyrosine and glycine derivatives as potential prodrugs: design, synthesis, and pharmacological evaluation of amide derivatives of mefenamic acid | Full Text | References | PDF (1,012.2 KB)
  • 2153 Views
  • 6 CrossRef citations
  • 0Altmetric
Free Access

Research Article

Article
Tyrosinase inhibitory effect of benzoic acid derivatives and their structure-activity relationships
Sher Bahadar Khan, Mahmud Tareq Hassan Khan, Eui Sung Jang, Kalsoom Akhtar, Jongchul Seo & Haksoo Han
Pages: 812-817
Published online: 17 May 2010
AbstractforTyrosinase inhibitory effect of benzoic acid derivatives and their structure-activity relationships | Full Text | References | PDF (625.8 KB)
  • 2062 Views
  • 12 CrossRef citations
  • 0Altmetric
Free Access
Article
Design, synthesis and anti-Parkinsonian evaluation of 3-alkyl/aryl-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thiones against neuroleptic-induced catalepsy and oxidative stress in mice
Faizul Azam, Bashir A. El-gnidi, Ismail A. Alkskas & Musa A. Ahmed
Pages: 818-826
Published online: 30 Apr 2010
AbstractforDesign, synthesis and anti-Parkinsonian evaluation of 3-alkyl/aryl-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thiones against neuroleptic-induced catalepsy and oxidative stress in mice | Full Text | References | PDF (769.7 KB)
  • 744 Views
  • 25 CrossRef citations
  • 0Altmetric
Free Access
Article
Design, synthesis and anticholinesterase activity of some new α-aminobisphosphonates
Khodayar Gholivand, Fatemeh Ghaziani, Rouhollah Yaghoubi, Zahra Hosseini & Zahra Shariatinia
Pages: 827-835
Published online: 30 Mar 2010
AbstractforDesign, synthesis and anticholinesterase activity of some new α-aminobisphosphonates | Full Text | References | PDF (869 KB)
  • 931 Views
  • 17 CrossRef citations
  • 0Altmetric
Free Access
Article
Chemopreventive potential of 3-[2,6-bis(4-fluorophenyl)-3-methylpiperidin-4-ylideneamino]-2-thioxoimidazolidin-4-one on 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis
J. Thanusu, V. Kanagarajan, S. Nagini & M. Gopalakrishnan
Pages: 836-843
Published online: 07 Apr 2010
AbstractforChemopreventive potential of 3-[2,6-bis(4-fluorophenyl)-3-methylpiperidin-4-ylideneamino]-2-thioxoimidazolidin-4-one on 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis | Full Text | References | PDF (651.2 KB)
  • 512 Views
  • 7 CrossRef citations
  • 0Altmetric
Free Access
Article
Quantitative structure–activity relationship (QSAR) study of interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor activity by the genetic algorithm and multiple linear regression (GA-MLR) method
Eslam Pourbasheer, Siavash Riahi, Mohammad Reza Ganjali & Parviz Norouzi
Pages: 844-853
Published online: 30 Apr 2010
AbstractforQuantitative structure–activity relationship (QSAR) study of interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor activity by the genetic algorithm and multiple linear regression (GA-MLR) method | Full Text | References | PDF (1.3 MB)
  • 1821 Views
  • 35 CrossRef citations
  • 0Altmetric
Free Access
Article
Glutathione transferase from Plasmodium falciparum – Interaction with malagashanine and selected plant natural products
Rumbidzai Mangoyi, Rose Hayeshi, Bonventure Ngadjui, Francois Ngandeu, Merhatibebe Bezabih, Berhanu Abegaz, Solofoniaina Razafimahefa, Philippe Rasoanaivo & Stanley Mukanganyama
Pages: 854-862
Published online: 03 Jun 2010
AbstractforGlutathione transferase from Plasmodium falciparum – Interaction with malagashanine and selected plant natural products | Full Text | References | PDF (856.2 KB)
  • 1215 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access
Article
Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides
Lina Baranauskienė, Mika Hilvo, Jurgita Matulienė, Dmitrij Golovenko, Elena Manakova, Virginija Dudutienė, Vilma Michailovienė, Jolanta Torresan, Jelena Jachno, Seppo Parkkila, Alfonso Maresca, Claudiu T. Supuran, Saulius Gražulis & Daumantas Matulis
Pages: 863-870
Published online: 18 Feb 2010
AbstractforInhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides | Full Text | References | PDF (850.9 KB)
  • 1765 Views
  • 66 CrossRef citations
  • 0Altmetric
Free Access
Article
Effects of some drugs on human erythrocyte glucose 6-phosphate dehydrogenase: an in vitro study
Ebru Akkemik, Harun Budak & Mehmet Ciftci
Pages: 871-875
Published online: 08 Nov 2010
AbstractforEffects of some drugs on human erythrocyte glucose 6-phosphate dehydrogenase: an in vitro study | Full Text | References | PDF (609.1 KB)
  • 3867 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access
Article
Inhibitory effects of phthalimide derivatives on the activity of the hepatic cytochrome P450 monooxygenases CYP2C9 and CYP2C19
Üner Kolukisaoglu, Christian Wendler, Dirk Goerdes, Annette Diener & Kerstin Thurow
Pages: 876-886
Published online: 28 Jun 2010
AbstractforInhibitory effects of phthalimide derivatives on the activity of the hepatic cytochrome P450 monooxygenases CYP2C9 and CYP2C19 | Full Text | References | PDF (2 MB)
  • 692 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access
Article
Constituents of Limonia acidissima inhibit LPS-induced nitric oxide production in BV-2 microglia
Ki Hyun Kim, Sang Keun Ha, Sun Yeou Kim, Hyun Joo Youn & Kang Ro Lee
Pages: 887-892
Published online: 28 Jun 2010
AbstractforConstituents of Limonia acidissima inhibit LPS-induced nitric oxide production in BV-2 microglia | Full Text | References | PDF (662.7 KB)
  • 1024 Views
  • 14 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis and antimycobacterial evaluation of various 6-substituted pyrazolo[3,4-d]pyrimidine derivatives
Amit Trivedi, Shailesh Vaghasiya, Bipin Dholariya, Dipti Dodiya & Viresh Shah
Pages: 893-899
Published online: 08 Nov 2010
AbstractforSynthesis and antimycobacterial evaluation of various 6-substituted pyrazolo[3,4-d]pyrimidine derivatives | Full Text | References | PDF (644.8 KB)
  • 556 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access

Explore articles

Explore the most recently published articles

The activity of pyrazolo[4,3-e][1,2,4]triazine and pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures
Anna Szymanowska et al.
Article | Published online: 3 May 2024
Open Access
Discovery of novel FGFR4 inhibitors through a build-up fragment strategy
Jihyung Kim et al.
Brief Report | Published online: 24 Apr 2024
Open Access
Targeting bacterial growth in biofilm conditions: rational design of novel inhibitors to mitigate clinical and food contamination using QSAR
Maria Galvez-Llompart et al.
Article | Published online: 23 Apr 2024
Open Access
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells
Loredana Salerno et al.
Brief Report | Published online: 18 Apr 2024
Open Access