Acta Oncologica, Volume 52, Issue 3 (2013)

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Acta Oncologica, Volume 52, Issue 3 (2013)

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Editorial

Editorial
Establishing and expanding the indications for proton and particle therapy
Ludvig P. Muren, Carl Rossi, Eugen Hug, Andrew Lee & Bengt Glimelius
Pages: 459-462
Published online: 12 Mar 2013
First Page PreviewforEstablishing and expanding the indications for proton and particle therapy | Full Text | References | PDF (59.6 KB)
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Acta Oncologica Jubilee Article

Article
Urinary functional outcomes and toxicity five years after proton therapy for low- and intermediate-risk prostate cancer: Results of two prospective trials
Randal H. Henderson, Bradford S. Hoppe, Robert B. Marcus Jr, William M. Mendenhall, R. Charles Nichols, Zuofeng Li, Zhong Su, Christopher G. Morris, Christopher R. Williams, Joseph Costa & Nancy P. Mendenhall
Pages: 463-469
Published online: 12 Mar 2013
AbstractforUrinary functional outcomes and toxicity five years after proton therapy for low- and intermediate-risk prostate cancer: Results of two prospective trials | Full Text | References | PDF (71.2 KB)
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Original Articles

Article
Outcomes in men with large prostates (≥ 60 cm3) treated with definitive proton therapy for prostate cancer
Lisa Mcgee, Nancy P. Mendenhall, Randal H. Henderson, Christopher G. Morris, Romaine C. Nichols Jr, Robert J. Marcus Jr, Zuofeng Li, William M. Mendenhall, Christopher R. Williams & Bradford S. Hoppe
Pages: 470-476
Published online: 17 Dec 2012
AbstractforOutcomes in men with large prostates (≥ 60 cm3) treated with definitive proton therapy for prostate cancer | Full Text | References | PDF (73.1 KB)
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Article
A phase II study of hypofractionated proton therapy for prostate cancer
Yeon-Joo Kim, Kwan Ho Cho, Hong Ryull Pyo, Kang Hyun Lee, Sung Ho Moon, Tae Hyun Kim, Kyung Hwan Shin, Joo-Young Kim, Se Byeong Lee & Byong Ho Nam
Pages: 477-485
Published online: 11 Feb 2013
AbstractforA phase II study of hypofractionated proton therapy for prostate cancer | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
Hip fractures and pain following proton therapy for management of prostate cancer
Raul Valery, Nancy P. Mendenhall, Romaine C. Nichols Jr, Randal Henderson, Christopher G. Morris, Zhong Su, William M. Mendenhall, Christopher R. Williams, Zuofeng Li & Bradford S. Hoppe
Pages: 486-491
Published online: 29 Jan 2013
AbstractforHip fractures and pain following proton therapy for management of prostate cancer | Full Text | References | PDF (63.1 KB)
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Article
Hypofractionated passively scattered proton radiotherapy for low- and intermediate-risk prostate cancer is not associated with post-treatment testosterone suppression
Whoon Jong Kil, Romaine C. Nichols Jr, Bradford S. Hoppe, Christopher G. Morris, Robert B. Marcus Jr, William Mendenhall, Nancy P. Mendenhall, Zuofeng Li, Joseph A. Costa, Christopher R. Williams & Randal H. Henderson
Pages: 492-497
Published online: 12 Mar 2013
AbstractforHypofractionated passively scattered proton radiotherapy for low- and intermediate-risk prostate cancer is not associated with post-treatment testosterone suppression | Full Text | References | PDF (182.3 KB)
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Article
Proton therapy with concomitant capecitabine for pancreatic and ampullary cancers is associated with a low incidence of gastrointestinal toxicity
R. Charles Nichols Jr, Thomas J. George, Robert A. Zaiden Jr, Ziad T. Awad, Horacio J. Asbun, Soon Huh, Meng Wei Ho, Nancy P. Mendenhall, Christopher G. Morris & bradford S. Hoppe
Pages: 498-505
Published online: 12 Mar 2013
AbstractforProton therapy with concomitant capecitabine for pancreatic and ampullary cancers is associated with a low incidence of gastrointestinal toxicity | Full Text | References | PDF (195.5 KB) | Supplemental
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Article
Dosimetric rationale and early experience at UFPTI of thoracic proton therapy and chemotherapy in limited-stage small cell lung cancer
Rovel J. Colaco, Soon Huh, Romaine C. Nichols, Christopher G. Morris, Harry D’Agostino, Stella Flampouri, Zuofeng Li, Dat C. Pham, Abubakr A. Bajwa & Bradford S. Hoppe
Pages: 506-513
Published online: 26 Feb 2013
AbstractforDosimetric rationale and early experience at UFPTI of thoracic proton therapy and chemotherapy in limited-stage small cell lung cancer | Full Text | References | PDF (115 KB)
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Article
Prospective evaluation of early treatment outcome in patients with meningiomas treated with particle therapy based on target volume definition with MRI and 68Ga-DOTATOC-PET
Stephanie E. Combs, Thomas Welzel, Daniel Habermehl, Stefan Rieken, Jan-Oliver Dittmar, Kerstin Kessel, Oliver Jäkel, Uwe Haberkorn & Jürgen Debus
Pages: 514-520
Published online: 12 Feb 2013
AbstractforProspective evaluation of early treatment outcome in patients with meningiomas treated with particle therapy based on target volume definition with MRI and 68Ga-DOTATOC-PET | Full Text | References | PDF (306.8 KB)
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Article
Degradation of target coverage due to inter-fraction motion during intensity-modulated proton therapy of prostate and elective targets
Sara Thörnqvist, Ludvig P. Muren, Lise Bentzen, Liv B. Hysing, Morten Høyer, Cai Grau & Jørgen B. B. Petersen
Pages: 521-527
Published online: 14 Feb 2013
AbstractforDegradation of target coverage due to inter-fraction motion during intensity-modulated proton therapy of prostate and elective targets | Full Text | References | PDF (187.7 KB)
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Article
Integrated peripheral boost in preoperative radiotherapy for the locally most advanced non-resectable rectal cancer patients
Calin Radu, Ola Norrlid, Morten Brændengen, Karl Hansson, Ulf Isacsson & Bengt Glimelius
Pages: 528-537
Published online: 01 Nov 2012
AbstractforIntegrated peripheral boost in preoperative radiotherapy for the locally most advanced non-resectable rectal cancer patients | Full Text | References | PDF (340.1 KB)
  • 1043 Views
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Article
Dose-volume histogram analysis for risk factors of radiation-induced rib fracture after hypofractionated proton beam therapy for hepatocellular carcinoma
Ayae Kanemoto, Masashi Mizumoto, Toshiyuki Okumura, Hideto Takahashi, Takayuki Hashimoto, Yoshiko Oshiro, Nobuyoshi Fukumitsu, Takashi Moritake, Koji Tsuboi, Takeji Sakae & Hideyuki Sakurai
Pages: 538-544
Published online: 05 Sep 2012
AbstractforDose-volume histogram analysis for risk factors of radiation-induced rib fracture after hypofractionated proton beam therapy for hepatocellular carcinoma | Full Text | References | PDF (352.1 KB)
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Article
Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy
Antonella Fogliata, Marta Scorsetti, Piera Navarria, Maddalena Catalano, Alessandro Clivio, Luca Cozzi, Francesca Lobefalo, Giorgia Nicolini, Valentina Palumbo, Chiara Pellegrini, Giacomo Reggiori, Antonella Roggio, Eugenio Vanetti, Filippo Alongi, Sara Pentimalli & Pietro Mancosu
Pages: 545-552
Published online: 07 Jun 2012
AbstractforDosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy | Full Text | References | PDF (203.3 KB)
  • 2017 Views
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Article
Dosimetric comparison between proton and photon beams in the moving gap region in cranio-spinal irradiation (CSI)
Chee-Wai Cheng, Indra J. Das, Shiv P. Srivastava, Li Zhao, Mark Wolanski, Joseph Simmons, Peter A.S. Johnstone & Jeffrey C. Buchsbaum
Pages: 553-560
Published online: 04 May 2012
AbstractforDosimetric comparison between proton and photon beams in the moving gap region in cranio-spinal irradiation (CSI) | Full Text | References | PDF (543.5 KB)
  • 1289 Views
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Article
The potential of intensity-modulated proton radiotherapy to reduce swallowing dysfunction in the treatment of head and neck cancer: A planning comparative study
Hans Paul van der Laan, Tara A. van de Water, Heleen E. van Herpt, Miranda E. M. C. Christianen, Hendrik P. Bijl, Erik. W. Korevaar, Coen R. Rasch, Aart A. van ‘T Veld, Arjen van der Schaaf, Cornelis Schilstra, Johannes A. Langendijk & on behalf of the Rococo cooperative group
Pages: 561-569
Published online: 19 Jun 2012
AbstractforThe potential of intensity-modulated proton radiotherapy to reduce swallowing dysfunction in the treatment of head and neck cancer: A planning comparative study | Full Text | References | PDF (307.5 KB)
  • 2861 Views
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Article
Robustness of IMPT treatment plans with respect to inter-fractional set-up uncertainties: Impact of various beam arrangements for cranial targets
Johannes Hopfgartner, Markus Stock, Barbara Knäusl & Dietmar Georg
Pages: 570-579
Published online: 17 Dec 2012
AbstractforRobustness of IMPT treatment plans with respect to inter-fractional set-up uncertainties: Impact of various beam arrangements for cranial targets | Full Text | References | PDF (276 KB)
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Article
A model for the relative biological effectiveness of protons: The tissue specific parameter α/β of photons is a predictor for the sensitivity to LET changes
Minna Wedenberg, Bengt K. Lind & Björn Hårdemark
Pages: 580-588
Published online: 22 Aug 2012
AbstractforA model for the relative biological effectiveness of protons: The tissue specific parameter α/β of photons is a predictor for the sensitivity to LET changes | Full Text | References | PDF (913.8 KB) | Supplemental
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Letters to the Editor

Letter
Particle species dependence of cell survival RBE: Evident and not negligible
Thomas Friedrich, Marco Durante & Michael Scholz
Pages: 589-603
Published online: 15 Feb 2013
CitationforParticle species dependence of cell survival RBE: Evident and not negligible | Full Text | References | PDF (363.3 KB)
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Letter
In response to the commentary ‘Particle species dependence of cell survival relative biological effectiveness: Evident and not negligible’ by Thomas Friedrich, Marco Durante & Michael Scholz
Brita Singers Sørensen, Jens Overgaard & Niels Bassler
Page: 591
Published online: 19 Feb 2013
CitationforIn response to the commentary ‘Particle species dependence of cell survival relative biological effectiveness: Evident and not negligible’ by Thomas Friedrich, Marco Durante & Michael Scholz | Full Text | References | PDF (31.8 KB)
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Article
Proton therapy in a pediatric patient with stage III Hodgkin lymphoma
Adam Holtzman, Stella Flampouri, Zuofeng Li, Nancy P. Mendenhall & Bradford S. Hoppe
Pages: 592-594
Published online: 12 Mar 2013
First Page PreviewforProton therapy in a pediatric patient with stage III Hodgkin lymphoma | Full Text | References | PDF (284.3 KB)
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Letter
A treatment planning comparison of highly conformal radiation therapy for pediatric low-grade brainstem gliomas
Jeffrey V. Brower, Daniel J. Indelicato, Philipp R. Aldana, Eric Sandler, Ronny Rotondo, Nancy P. Mendenhall, Robert B. Marcus & Zhong Su
Pages: 594-599
Published online: 20 Feb 2013
First Page PreviewforA treatment planning comparison of highly conformal radiation therapy for pediatric low-grade brainstem gliomas | Full Text | References | PDF (3.7 MB) | Supplemental
  • 1078 Views
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Letter
Proton beam therapy for unresectable hepatoblastoma in children: Survival in one case
Yoshiko Oshiro, Toshiyuki Okumura, Masashi Mizumoto, Takashi fukushima, Hitoshi Ishikawa, Takayuki Hashimoto, Koji Tsuboi, Michio Kaneko & Hideyuki Sakurai
Pages: 600-603
Published online: 15 Jan 2013
First Page PreviewforProton beam therapy for unresectable hepatoblastoma in children: Survival in one case | Full Text | References | PDF (444 KB)
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Original Articles

Article
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: A preclinical study of cervical carcinoma and melanoma xenografts
Kirsti Marie Øvrebø, Christine Ellingsen, Tord Hompland & Einar K. Rofstad
Pages: 604-611
Published online: 07 Jun 2012
AbstractforDynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: A preclinical study of cervical carcinoma and melanoma xenografts | Full Text | References | PDF (325.9 KB)
  • 990 Views
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Article
T1/T2*-weighted MRI provides clinically relevant pseudo-CT density data for the pelvic bones in MRI-only based radiotherapy treatment planning
Mika Kapanen & Mikko Tenhunen
Pages: 612-618
Published online: 19 Jun 2012
AbstractforT1/T2*-weighted MRI provides clinically relevant pseudo-CT density data for the pelvic bones in MRI-only based radiotherapy treatment planning | Full Text | References | PDF (1.2 MB)
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Article
Early prediction of pathological response in locally advanced rectal cancer based on sequential 18F-FDG PET
Mathieu Hatt, Ruud van Stiphout, Adrien le Pogam, Guido Lammering, Dimitris Visvikis & Philippe Lambin
Pages: 619-626
Published online: 08 Aug 2012
AbstractforEarly prediction of pathological response in locally advanced rectal cancer based on sequential 18F-FDG PET | Full Text | References | PDF (312.1 KB) | Supplemental
  • 906 Views
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Article
Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights
Tord Hompland, Kristine Gulliksrud, Christine Ellingsen & Einar K. Rofstad
Pages: 627-635
Published online: 06 Nov 2012
AbstractforAssessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights | Full Text | References | PDF (2.7 MB)
  • 1160 Views
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Article
A gel tumour phantom for assessment of the accuracy of manual and automatic delineation of gross tumour volume from FDG-PET/CT
Arne Skretting, Jan F. Evensen, Ayca M. Løndalen, Trond V. Bogsrud, Otto K. Glomset & Karsten Eilertsen
Pages: 636-644
Published online: 17 Oct 2012
AbstractforA gel tumour phantom for assessment of the accuracy of manual and automatic delineation of gross tumour volume from FDG-PET/CT | Full Text | References | PDF (184.2 KB) | Supplemental
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Article
Treatment plan comparison using grading analysis based on clinical judgment
Kristoffer Petersson, Jacob Engellau, Per Nilsson, Per Engström, Tommy Knöös & Crister Ceberg
Pages: 645-651
Published online: 16 Dec 2012
AbstractforTreatment plan comparison using grading analysis based on clinical judgment | Full Text | References | PDF (2 MB) | Supplemental
  • 797 Views
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Article
Comparable cell survival between high dose rate flattening filter free and conventional dose rate irradiation
Wilko F.A.R. Verbakel, Jaap van den Berg, Ben J. Slotman & Peter Sminia
Pages: 652-657
Published online: 06 Nov 2012
AbstractforComparable cell survival between high dose rate flattening filter free and conventional dose rate irradiation | Full Text | References | PDF (149.1 KB)
  • 1766 Views
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Article
Improved tumour control probability with MRI-based prostate brachytherapy treatment planning
Anna M. Dinkla, Bradley R. Pieters, Kees Koedooder, Niek van Wieringen, Rob van der Laarse, Johan N. van der Grient, Coen R. Rasch, Caro C. Koning & Arjan Bel
Pages: 658-665
Published online: 03 Jan 2013
AbstractforImproved tumour control probability with MRI-based prostate brachytherapy treatment planning | Full Text | References | PDF (842 KB) | Supplemental
  • 932 Views
  • 15 CrossRef citations
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Article
Statistical simulations to estimate motion-inclusive dose-volume histograms for prediction of rectal morbidity following radiotherapy
Maria Thor, Aditya Apte, Joseph O. Deasy & Ludvig Paul Muren
Pages: 666-675
Published online: 04 Dec 2012
AbstractforStatistical simulations to estimate motion-inclusive dose-volume histograms for prediction of rectal morbidity following radiotherapy | Full Text | References | PDF (409 KB) | Supplemental
  • 775 Views
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Letter to the Editor

Letter
Tumor size does not predict pathological complete response rates after pre-operative chemoradiotherapy for non-small cell lung cancer
Cornelis G. Vos, Max Dahele, Chris Dickhoff, Suresh Senan, Erik Thunnissen & Koen J. Hartemink
Pages: 676-678
Published online: 25 Oct 2012
First Page PreviewforTumor size does not predict pathological complete response rates after pre-operative chemoradiotherapy for non-small cell lung cancer | Full Text | References | PDF (49.4 KB)
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