Journal of Inflammation Research, Volume 16, Issue (2023)

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Journal of Inflammation Research, Volume 16, Issue (2023)

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ORIGINAL RESEARCH

Article
Autoimmune Hemolytic Anemia After Cord Blood Transplantation: A Retrospective Single-Center Experience
Jing Yuan, Ze-Yin Liang, Yu-Jun Dong & Han-Yun Ren
Pages: 1-6
Published online: 04 Jan 2023
AbstractforAutoimmune Hemolytic Anemia After Cord Blood Transplantation: A Retrospective Single-Center Experience | Full Text | References | PDF (368.7 KB) | EPUB
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Open Access
Article
Inflammatory and Nutritional Scoring System for Predicting Prognosis in Patients with Newly Diagnosed Multiple Myeloma
Limei Zhang, Shuzhao Chen, Weida Wang, Yun Wang & Yang Liang
Pages: 7-17
Published online: 05 Jan 2023
AbstractforInflammatory and Nutritional Scoring System for Predicting Prognosis in Patients with Newly Diagnosed Multiple Myeloma | Full Text | References | PDF (601.2 KB) | EPUB
  • 351 Views
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HYPOTHESIS

C-Type Lectin Receptors-Triggered Antifungal Immunity May Synergize with and Optimize the Effects of Immunotherapy in Hepatocellular Carcinoma
Jinkun Xia, Haoran Ding, Shujun Liu, Ran An, Xiaolei Shi, Ming Chen & Haozhen Ren
Pages: 19-33
Published online: 05 Jan 2023
AbstractforC-Type Lectin Receptors-Triggered Antifungal Immunity May Synergize with and Optimize the Effects of Immunotherapy in Hepatocellular Carcinoma | Full Text | References | PDF (8.5 MB) | EPUB
  • 260 Views
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REVIEW

Review
Effects of Neuropeptides on Dendritic Cells in the Pathogenesis of Psoriasis
Jingya Zhang, Siqi Zhao, Xinzhu Xing, Lin Shang, Jiali Cao & Yanling He
Pages: 35-43
Published online: 06 Jan 2023
AbstractforEffects of Neuropeptides on Dendritic Cells in the Pathogenesis of Psoriasis | Full Text | References | PDF (2.5 MB) | EPUB
  • 319 Views
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Open Access
Review
WKYMVm Works by Targeting Immune Cells
Yuting Yang, Jin Zhao, Chunmeng Jiang, Yue Zhang, Mei Han & Hui Liu
Pages: 45-55
Published online: 06 Jan 2023
AbstractforWKYMVm Works by Targeting Immune Cells | Full Text | References | PDF (3.7 MB) | EPUB
  • 208 Views
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Open Access
Review
Pathogenesis and Therapy of Coagulation Disorders in Severe Acute Pancreatitis
Menglu Gui, Bing Zhao, Jun Huang, Erzhen Chen, Hongping Qu & Enqiang Mao
Pages: 57-67
Published online: 06 Jan 2023
AbstractforPathogenesis and Therapy of Coagulation Disorders in Severe Acute Pancreatitis | Full Text | References | PDF (2.3 MB) | EPUB
  • 362 Views
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Open Access
Review
Fashionable, but What is Their Real Clinical Usefulness? NLR, LMR, and PLR as a Promising Indicator in Colorectal Cancer Prognosis: A Systematic Review
Aleksandra Misiewicz & Violetta Dymicka-Piekarska
Pages: 69-81
Published online: 07 Jan 2023
AbstractforFashionable, but What is Their Real Clinical Usefulness? NLR, LMR, and PLR as a Promising Indicator in Colorectal Cancer Prognosis: A Systematic Review | Full Text | References | PDF (4.2 MB) | EPUB
  • 621 Views
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ORIGINAL RESEARCH

Article
Anti-Inflammatory and Antioxidant Effects of Liposoluble C60 at the Cellular, Molecular, and Whole-Animal Levels
Mizhou Hui, Xiaoxiao Jia, Xinrong Li, Rayko Lazcano-Silveira & Ming Shi
Pages: 83-93
Published online: 07 Jan 2023
AbstractforAnti-Inflammatory and Antioxidant Effects of Liposoluble C60 at the Cellular, Molecular, and Whole-Animal Levels | Full Text | References | PDF (4.6 MB) | EPUB
  • 337 Views
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Open Access
Article
Up-Regulation of ProBDNF/p75NTR Signaling in Spinal Cord Drives Inflammatory Pain in Male Rats
Hui Li, Tao Liu, Jingjing Sun, Shuai Zhao, Xin Wang, Wei Luo, Ruyi Luo, Weiyun Shen, Cong Luo & Di Fu
Pages: 95-107
Published online: 09 Jan 2023
AbstractforUp-Regulation of ProBDNF/p75NTR Signaling in Spinal Cord Drives Inflammatory Pain in Male Rats | Full Text | References | PDF (11.9 MB) | EPUB
  • 289 Views
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Open Access
Article
Theaflavin-3,3’-Digallate Ameliorates Collagen-Induced Arthritis Through Regulation of Autophagy and Macrophage Polarization
Lei Zhang, Wenming Li, Zhenyang Hou, Zhidong Wang, Wei Zhang, Xiaolong Liang, Zerui Wu, Tianhao Wang, Xin Liu, Xiaole Peng, Xing Yang, Huilin Yang & Dechun Geng
Pages: 109-126
Published online: 10 Jan 2023
AbstractforTheaflavin-3,3’-Digallate Ameliorates Collagen-Induced Arthritis Through Regulation of Autophagy and Macrophage Polarization | Full Text | References | PDF (14.3 MB) | EPUB
  • 340 Views
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Open Access
Article
Characteristics and Incidence of Colon Complication in Necrotizing pancreatitis: A Propensity Score-Matched Study
Jiongdi Lu, Zhi Zheng, Yixuan Ding, Yuanxu Qu, Wentong Mei, Zhen Fang, Chang Qu, Yulu Feng, Yulin Guo, Chongchong Gao, Feng Cao & Fei Li
Pages: 127-144
Published online: 11 Jan 2023
AbstractforCharacteristics and Incidence of Colon Complication in Necrotizing pancreatitis: A Propensity Score-Matched Study | Full Text | References | PDF (2.1 MB) | EPUB
  • 215 Views
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Open Access
Article
The Levels of Anti-SARS-CoV-2 Spike Protein IgG Antibodies Before and After the Third Dose of Vaccination Against COVID-19
Małgorzata Łysek-Gładysińska, Magdalena Starz, Agnieszka Borowiec-Sęk, Iwona Sufin, Anna Wieczorek, Magdalena Chrapek, Dorota Zarębska-Michaluk, Patrycja Sufin, Stanisław Głuszek & Wioletta Adamus-Białek
Pages: 145-160
Published online: 11 Jan 2023
AbstractforThe Levels of Anti-SARS-CoV-2 Spike Protein IgG Antibodies Before and After the Third Dose of Vaccination Against COVID-19 | Full Text | References | PDF (3.4 MB) | EPUB
  • 331 Views
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REVIEW

Review
Review of Neurofilaments as Biomarkers in Sepsis-Associated Encephalopathy
Qiulei Zhang, Weixuan Fan, Jian Sun, Jingxiao Zhang & Yongjie Yin
Pages: 161-168
Published online: 11 Jan 2023
AbstractforReview of Neurofilaments as Biomarkers in Sepsis-Associated Encephalopathy | Full Text | References | PDF (2.2 MB) | EPUB
  • 340 Views
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Open Access

ORIGINAL RESEARCH

Article
CHINAT-CD4 Score Predicts Transplant-Free Survival in Patients with Acute-on-Chronic Liver Failure
Chenlu Huang, Weixia Li, Chong Chen, Wei Xu, Ling Fei, Shuai Tao, Qiankun Hu, Xudong Xie, Xiongyue Cao, Xiao-Yu Zhang, Liang Chen, Qiang Li & Yuxian Huang
Pages: 197-207
Published online: 13 Jan 2023
AbstractforCHINAT-CD4 Score Predicts Transplant-Free Survival in Patients with Acute-on-Chronic Liver Failure | Full Text | References | PDF (3.7 MB) | EPUB
  • 148 Views
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Open Access
Article
Anti-Inflammatory Effects of the 35kDa Hyaluronic Acid Fragment (B-HA/HA35)
XiaoXiao Jia, Ming Shi, Qifei Wang, Jessica Hui, Joshua Hui Shofaro, Ryenchindorj Erkhembayar, Mizhou Hui, Chenzhe Gao & Munkh-Amgalan Gantumur
Pages: 209-224
Published online: 13 Jan 2023
AbstractforAnti-Inflammatory Effects of the 35kDa Hyaluronic Acid Fragment (B-HA/HA35) | Full Text | References | PDF (9.8 MB) | EPUB
  • 437 Views
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Open Access
Article
Nomograms Based on the Albumin/Neutrophil-to-Lymphocyte Ratio Score for Predicting Coronary Artery Disease or Subclinical Coronary Artery Disease
Chen Wei, Wenjun Fan, Ying Zhang, Yixiang Liu, Zhenjiang Ding, Yueqiao Si, Jingyi Liu & Lixian Sun
Pages: 169-182
Published online: 13 Jan 2023
AbstractforNomograms Based on the Albumin/Neutrophil-to-Lymphocyte Ratio Score for Predicting Coronary Artery Disease or Subclinical Coronary Artery Disease | Full Text | References | PDF (7 MB) | EPUB
  • 235 Views
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RAPID COMMUNICATION

Rapid Communication
Platelet/Lymphocyte Ratio Predicted Long-Term Prognosis for Acute Upper Extremity Deep Vein Thrombosis from a Retrospective Study
Yang Liu, Hongze Sun & Jianjun Jiang
Pages: 225-234
Published online: 14 Jan 2023
AbstractforPlatelet/Lymphocyte Ratio Predicted Long-Term Prognosis for Acute Upper Extremity Deep Vein Thrombosis from a Retrospective Study | Full Text | References | PDF (2.3 MB) | EPUB
  • 185 Views
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ORIGINAL RESEARCH

Article
Prevalence, General and Periodontal Risk Factors of Gastroesophageal Reflux Disease in China
Zhiqiang Liu, Xiaoli Gao, Lirong Liang, Xuan Zhou, Xiaozhe Han, Ting Yang, Kewu Huang, Yingxiang Lin, Shu Deng, Zuomin Wang & Chen Wang
Pages: 235-244
Published online: 17 Jan 2023
AbstractforPrevalence, General and Periodontal Risk Factors of Gastroesophageal Reflux Disease in China | Full Text | References | PDF (3.8 MB) | EPUB
  • 535 Views
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Open Access
Article
Biological Functions of Selenoprotein Glutathione Peroxidases (GPXs) and their Expression in Osteoarthritis
Qianqian Zhao, Yongliang Tang, Luyu Zhang, Na Sun, Qiling Liu & Rongqiang Zhang
Pages: 183-196
Published online: 13 Jan 2023
AbstractforBiological Functions of Selenoprotein Glutathione Peroxidases (GPXs) and their Expression in Osteoarthritis | Full Text | References | PDF (7.2 MB) | EPUB
  • 281 Views
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Article
The Association of Inflammatory Markers with Maternal-Neonatal Outcome After Cervical Cerclage
Jiaoning Fang, Yingying Lin, Zhiwei Chen, Yan Lin & Mian Pan
Pages: 245-255
Published online: 19 Jan 2023
AbstractforThe Association of Inflammatory Markers with Maternal-Neonatal Outcome After Cervical Cerclage | Full Text | References | PDF (1.1 MB) | EPUB
  • 315 Views
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Article
Effect of Triglyceride-Glucose Indices and Circulating PCSK9-Associated Cardiovascular Risk in STEMI Patients with Primary Percutaneous Coronary Artery Disease: A Prospective Cohort Study
Xiaoxiao Zhao, Li Song, Jiannan Li, Jinying Zhou, Nan Li, Shaodi Yan, Runzhen Chen, Ying Wang, Chen Liu, Peng Zhou, Zhaoxue Sheng, Yi Chen, Hanjun Zhao & Hongbing Yan
Pages: 269-282
Published online: 21 Jan 2023
AbstractforEffect of Triglyceride-Glucose Indices and Circulating PCSK9-Associated Cardiovascular Risk in STEMI Patients with Primary Percutaneous Coronary Artery Disease: A Prospective Cohort Study | Full Text | References | PDF (4.5 MB) | EPUB
  • 237 Views
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Article
Preoperative Systemic Inflammatory Markers as a Significant Prognostic Factor After TURBT in Patients with Non-Muscle-Invasive Bladder Cancer
Li Ding, Xiaobin Deng, Kun Wang, Wentao Xia, Yang Zhang, Yan Zhang, Xianfeng Shao & Junqi Wang
Pages: 283-296
Published online: 21 Jan 2023
AbstractforPreoperative Systemic Inflammatory Markers as a Significant Prognostic Factor After TURBT in Patients with Non-Muscle-Invasive Bladder Cancer | Full Text | References | PDF (6.6 MB) | EPUB
  • 206 Views
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Open Access
Article
Systemic Inflammation Markers Associated with Bone Mineral Density in perimenopausal and Postmenopausal Women
Yijie Chen, Jingjing Yu, Lan Shi, Shuyang Han, Jun Chen, Zhumei Sheng, Miao Deng, Xuejing Jin & Zhifen Zhang
Pages: 297-309
Published online: 22 Jan 2023
AbstractforSystemic Inflammation Markers Associated with Bone Mineral Density in perimenopausal and Postmenopausal Women | Full Text | References | PDF (1.8 MB) | EPUB
  • 324 Views
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REVIEW

Review
Mesenchymal Stromal/Stem Cell (MSC)-Based Vector Biomaterials for Clinical Tissue Engineering and Inflammation Research: A Narrative Mini Review
Junshuai Xue & Yang Liu
Pages: 257-267
Published online: 21 Jan 2023
AbstractforMesenchymal Stromal/Stem Cell (MSC)-Based Vector Biomaterials for Clinical Tissue Engineering and Inflammation Research: A Narrative Mini Review | Full Text | References | PDF (1.2 MB) | EPUB
  • 404 Views
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ORIGINAL RESEARCH

Article
Heparin-Binding Protein: A Prognostic Biomarker Associated with Severe or Complicated Community-Acquired Pneumonia in Children
Shuang Li, Yanwen Xu, Yuhang Wu, Heyu Huang, Chen Sun, Shanshan Xu, Huajun Li, Xi Zhang, Shiyong Zhao & Lisu Huang
Pages: 321-331
Published online: 26 Jan 2023
AbstractforHeparin-Binding Protein: A Prognostic Biomarker Associated with Severe or Complicated Community-Acquired Pneumonia in Children | Full Text | References | PDF (538 KB) | EPUB
  • 334 Views
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Article
Age–Bilirubin–International Normalized Ratio (INR)–Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI
Ting-Ting Wu, Ying Pan, Ying-Ying Zheng, Yi Yang, Xian-Geng Hou, Chang-Jiang Deng, Yi-Tong Ma & Xiang Xie
Pages: 333-341
Published online: 26 Jan 2023
AbstractforAge–Bilirubin–International Normalized Ratio (INR)–Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI | Full Text | References | PDF (1.5 MB) | EPUB
  • 216 Views
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Article
Serum YKL-40 Levels and White Matter Hyperintensities in Patients with Acute Ischemic Stroke
Guomei Shi, Dongdong Ke, Pengyu Gong, Peng Yu, Junshan Zhou, Meng Wang, Xiaohao Zhang, Xiaorong Wang, Minwang Guo, Mingyang Xu & Rujuan Zhou
Pages: 311-319
Published online: 25 Jan 2023
AbstractforSerum YKL-40 Levels and White Matter Hyperintensities in Patients with Acute Ischemic Stroke | Full Text | References | PDF (523.6 KB) | EPUB
  • 219 Views
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Article
Long-Term Trajectories of High-Sensitivity C-Reactive Protein Level Among Patients with Acute Heart Failure
Guangda He, Runqing Ji, Xiqian Huo, Xiaoming Su, Jinzhuo Ge, Wei Li, Lubi Lei, Boxuan Pu, Aoxi Tian, Jiamin Liu, Lihua Zhang, Yongjian Wu & On behalf of the China PEACE Collaborative Group
Pages: 359-371
Published online: 28 Jan 2023
AbstractforLong-Term Trajectories of High-Sensitivity C-Reactive Protein Level Among Patients with Acute Heart Failure | Full Text | References | PDF (2.9 MB) | EPUB
  • 204 Views
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Article
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway
Yuan Cao, Yulin Li, Wenqiang Han, Xu Jia, Ping Zhu, Bin Wei, Xiaoyan Cong & Zhihao Wang
Pages: 343-358
Published online: 27 Jan 2023
AbstractforSodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway | Full Text | References | PDF (11.4 MB) | EPUB
  • 274 Views
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Article
Shorter Cilia Length and Aberrant Ciliated Marker DNAI1 in Allergic Rhinitis
Suizi Zhou, Yitong Liu, Yueying Yang, Hongming Huang & Qianhui Qiu
Pages: 373-380
Published online: 30 Jan 2023
AbstractforShorter Cilia Length and Aberrant Ciliated Marker DNAI1 in Allergic Rhinitis | Full Text | References | PDF (2.7 MB) | EPUB
  • 193 Views
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REVIEW

Review
The Emerging Role of Ferroptosis in Various Chronic Liver Diseases: Opportunity or Challenge
Lujian Zhu, Shengnan Luo, Yin Zhu, Shiyue Tang, Chenge Li, Xiaozhi Jin, Faling Wu, Huimian Jiang, Lina Wu & Yejin Xu
Pages: 381-389
Published online: 31 Jan 2023
AbstractforThe Emerging Role of Ferroptosis in Various Chronic Liver Diseases: Opportunity or Challenge | Full Text | References | PDF (2.8 MB) | EPUB
  • 347 Views
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ORIGINAL RESEARCH

Article
Protectin DX Relieve Hyperoxia‐induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx
Zhongjie Liang, Huilin Yue, Congcong Xu, Qian Wang & Shengwei Jin
Pages: 421-431
Published online: 01 Feb 2023
AbstractforProtectin DX Relieve Hyperoxia‐induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx | Full Text | References | PDF (8.9 MB) | EPUB
  • 203 Views
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Open Access
Article
AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer’s Disease by Enhancing Autophagy
Yang Deng, Si-Yu Wang, Qing-Guang Wang, Zhao-Han Xu, Qiang Peng, Shuai-Yu Chen, Lin Zhu, Ying-Dong Zhang & Rui Duan
Pages: 391-406
Published online: 01 Feb 2023
AbstractforAVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer’s Disease by Enhancing Autophagy | Full Text | References | PDF (9.2 MB) | EPUB
  • 288 Views
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Article
Biomarkers Associated with Immune Checkpoint, N6-Methyladenosine, and Ferroptosis in Patients with Restenosis
Xiao Tong, Xinyi Zhao, Xuan Dang, Yan Kou & Junjie Kou
Pages: 407-420
Published online: 02 Feb 2023
AbstractforBiomarkers Associated with Immune Checkpoint, N6-Methyladenosine, and Ferroptosis in Patients with Restenosis | Full Text | References | PDF (9.2 MB) | EPUB
  • 241 Views
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Article
Noninvasive Evaluation of Lupus Nephritis Activity Using a Radiomics Machine Learning Model Based on Ultrasound
Xiachuan Qin, Linlin Xia, Chao Zhu, Xiaomin Hu, Weihan Xiao, Xisheng Xie & Chaoxue Zhang
Pages: 433-441
Published online: 03 Feb 2023
AbstractforNoninvasive Evaluation of Lupus Nephritis Activity Using a Radiomics Machine Learning Model Based on Ultrasound | Full Text | References | PDF (3.9 MB) | EPUB
  • 356 Views
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REVIEW

Review
Research on Liver Damage Caused by the Treatment of Rheumatoid Arthritis with Novel Biological Agents or Targeted Agents
Xin Zhao, Chenhao Zhang, Yi An, Zixuan Zhang, Jiahe Zhao, Xinwen Zhang, Yue Yang & Wei Cao
Pages: 443-452
Published online: 03 Feb 2023
AbstractforResearch on Liver Damage Caused by the Treatment of Rheumatoid Arthritis with Novel Biological Agents or Targeted Agents | Full Text | References | PDF (982.3 KB) | EPUB
  • 614 Views
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Review
Oxidative Stress Contributes to Inflammatory and Cellular Damage in Systemic Lupus Erythematosus: Cellular Markers and Molecular Mechanism
Zhu Yan, Qin Chen & Yumin Xia
Pages: 453-465
Published online: 04 Feb 2023
AbstractforOxidative Stress Contributes to Inflammatory and Cellular Damage in Systemic Lupus Erythematosus: Cellular Markers and Molecular Mechanism | Full Text | References | PDF (2.5 MB) | EPUB
  • 568 Views
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ORIGINAL RESEARCH

Article
Manjari Medika Grape Seed Extract Protects Methotrexate-Induced Hepatic Inflammation: Involvement of NF-κB/NLRP3 and Nrf2/HO-1 Signaling System
Krishnendu Manna, Zareen S Khan, Moumita Saha, Snehasis Mishra, Nilesh Gaikwad, Jatindra Nath Bhakta, Kaushik Banerjee & Krishna Das Saha
Pages: 467-492
Published online: 07 Feb 2023
AbstractforManjari Medika Grape Seed Extract Protects Methotrexate-Induced Hepatic Inflammation: Involvement of NF-κB/NLRP3 and Nrf2/HO-1 Signaling System | Full Text | References | PDF (15 MB) | EPUB
  • 523 Views
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Article
Association of Enolase-1 with Prognosis and Immune Infiltration in Breast Cancer by Clinical Stage
Yue-Yu Shi, Xing-Lei Chen, Qian-Xin Chen, Yuan-Zhong Yang, Meng Zhou, Yue-Xiang Ren, Lu-Ying Tang & Ze-Fang Ren
Pages: 493-503
Published online: 07 Feb 2023
AbstractforAssociation of Enolase-1 with Prognosis and Immune Infiltration in Breast Cancer by Clinical Stage | Full Text | References | PDF (3.1 MB) | EPUB
  • 245 Views
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Article
Nucleotide‐Binding Oligomerization Domain (NOD)-Like Receptor Subfamily C (NLRC) as a Prognostic Biomarker for Glioblastoma Multiforme Linked to Tumor Microenvironment: A Bioinformatics, Immunohistochemistry, and Machine Learning-Based Study
Shiyuan Han, Zimu Zhang, Wenbin Ma, Jun Gao & Yongning Li
Pages: 523-537
Published online: 10 Feb 2023
AbstractforNucleotide‐Binding Oligomerization Domain (NOD)-Like Receptor Subfamily C (NLRC) as a Prognostic Biomarker for Glioblastoma Multiforme Linked to Tumor Microenvironment: A Bioinformatics, Immunohistochemistry, and Machine Learning-Based Study | Full Text | References | PDF (12 MB) | EPUB
  • 315 Views
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Article
Identification and Validation of Immune-Related Genes Diagnostic for Progression of Atherosclerosis and Diabetes
Yajuan Fu, Lingbo Xu, Hui Zhang, Ning Ding, Juan Zhang, Shengchao Ma, Anning Yang, Yinjv Hao, Yujing Gao & Yideng Jiang
Pages: 505-521
Published online: 10 Feb 2023
AbstractforIdentification and Validation of Immune-Related Genes Diagnostic for Progression of Atherosclerosis and Diabetes | Full Text | References | PDF (14.4 MB) | EPUB
  • 320 Views
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Article
Investigation of the Underlying Mechanism of Sclerosteosis Expression in Muscle Tissue in Multiple Myeloma with Sarcopenia
Jie Ren, Jingzhou Wang, Xingchen Yao, Yue Wu, Ming Shi, Xiangjun Shi & Xinru Du
Pages: 563-578
Published online: 11 Feb 2023
AbstractforInvestigation of the Underlying Mechanism of Sclerosteosis Expression in Muscle Tissue in Multiple Myeloma with Sarcopenia | Full Text | References | PDF (10.2 MB) | EPUB
  • 240 Views
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Article
CD146+ Umbilical Cord Mesenchymal Stem Cells Exhibit High Immunomodulatory Activity and Therapeutic Efficacy in Septic Mice
Lin Zhang, Xiaoxu Zhang, Yubin Liu, Weiyuan Zhang, Chu-Tse Wu & Lisheng Wang
Pages: 579-594
Published online: 11 Feb 2023
AbstractforCD146+ Umbilical Cord Mesenchymal Stem Cells Exhibit High Immunomodulatory Activity and Therapeutic Efficacy in Septic Mice | Full Text | References | PDF (11.4 MB) | EPUB
  • 300 Views
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REVIEW

Review
Clinical Significance and Diagnostic Utility of NLR, LMR, PLR and SII in the Course of COVID-19: A Literature Review
Jakub Wiktor Kosidło, Blanka Wolszczak-Biedrzycka, Joanna Matowicka-Karna, Violetta Dymicka-Piekarska & Justyna Dorf
Pages: 539-562
Published online: 11 Feb 2023
AbstractforClinical Significance and Diagnostic Utility of NLR, LMR, PLR and SII in the Course of COVID-19: A Literature Review | Full Text | References | PDF (3.7 MB) | EPUB
  • 759 Views
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ORIGINAL RESEARCH

Article
The Value of the Monocyte to High-Density Lipoprotein Cholesterol Ratio in Assessing the Severity of Knee Osteoarthritis: A Retrospective Single Center Cohort Study
Jun Cao, Lin Hua, Liang Dong, Zhouhuan Wu & Guohui Xue
Pages: 595-604
Published online: 11 Feb 2023
AbstractforThe Value of the Monocyte to High-Density Lipoprotein Cholesterol Ratio in Assessing the Severity of Knee Osteoarthritis: A Retrospective Single Center Cohort Study | Full Text | References | PDF (2.2 MB) | EPUB
  • 279 Views
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Article
An Integrated Analysis Reveals Ciliary Abnormalities in Antrochoanal Polyps
Xiaoxue Zi, Yang Peng, Yiran Zang, Shiying Chen, Mengshi Li, Kena Yu, Xu Liang, Peng Jin, Deyun Wang & Li Shi
Pages: 605-615
Published online: 14 Feb 2023
AbstractforAn Integrated Analysis Reveals Ciliary Abnormalities in Antrochoanal Polyps | Full Text | References | PDF (6.6 MB) | EPUB
  • 189 Views
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Article
Associations Between Inflammatory Mediators and Bone Outcomes in Postmenopausal Women: A Cross-Sectional Analysis of Baseline Data from the Prune Study
Janhavi J Damani, Mary Jane De Souza, Nicole CA Strock, Kristen J Koltun, Nancy I Williams, Connie Weaver & Connie J Rogers
Pages: 639-663
Published online: 15 Feb 2023
AbstractforAssociations Between Inflammatory Mediators and Bone Outcomes in Postmenopausal Women: A Cross-Sectional Analysis of Baseline Data from the Prune Study | Full Text | References | PDF (844.3 KB) | EPUB
  • 474 Views
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Article
The Comprehensive Role of High Mobility Group Box 1 (HMGB1) Protein in Different Tumors: A Pan-Cancer Analysis
Hui Guan, Ming Zhong, Kongyang Ma, Chun Tang, Xiaohua Wang, Muzi Ouyang, Rencai Qin, Jiasi Chen, Enyi Zhu, Ting Zhu, Yongping Lu, Yu Liu, Chengzi Tian & Zhihua Zheng
Pages: 617-637
Published online: 14 Feb 2023
AbstractforThe Comprehensive Role of High Mobility Group Box 1 (HMGB1) Protein in Different Tumors: A Pan-Cancer Analysis | Full Text | References | PDF (17.8 MB) | EPUB
  • 428 Views
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Article
Impact of Toll-Like Receptor 2 and 9 Gene Polymorphisms on COVID-19: Susceptibility, Severity, and Thrombosis
Alshaymaa M Alhabibi, Asmaa S Hassan, Nashwa Mohamed Abd Elbaky, Hoda Asaad Eid, Mohie Aldeen Abd Alzaher Khalifa, Maisa A Wahab, Azza Ali Althoqapy, Aml E Abdou, Doaa Mohammed Zakaria, Eman Mostafa Nassef, Sammar Ahmed Kasim, Ola I Saleh, Asmaa Abdelghany Elsheikh, Mahmoud Lotfy & Alaa Sayed
Pages: 665-675
Published online: 17 Feb 2023
AbstractforImpact of Toll-Like Receptor 2 and 9 Gene Polymorphisms on COVID-19: Susceptibility, Severity, and Thrombosis | Full Text | References | PDF (502.3 KB) | EPUB
  • 354 Views
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Article
Preoperative Fibrinogen Albumin Ratio is an Effective Biomarker for Prognostic Evaluation of Gallbladder Carcinoma After Radical Resection: A 10-Year Retrospective Study at a Single Center
Qi Li, Jian Zhang, Qi Gao, Jialu Fu, Mengke Li, Hengchao Liu, Chen Chen, Dong Zhang & Zhimin Geng
Pages: 677-689
Published online: 18 Feb 2023
AbstractforPreoperative Fibrinogen Albumin Ratio is an Effective Biomarker for Prognostic Evaluation of Gallbladder Carcinoma After Radical Resection: A 10-Year Retrospective Study at a Single Center | Full Text | References | PDF (5.9 MB) | EPUB
  • 172 Views
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CASE REPORT

Case Report
An Unusual Case of Systemic Lymphadenopathy - Kimura’s Disease
Yongchang Liu, Shichang Liu, Jia Xu, Xiaocheng Xu & Meiyun Wang
Pages: 701-705
Published online: 18 Feb 2023
AbstractforAn Unusual Case of Systemic Lymphadenopathy - Kimura’s Disease | Full Text | References | PDF (540.7 KB) | EPUB
  • 250 Views
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ORIGINAL RESEARCH

Article
The Neutrophil Percentage-to-Albumin Ratio is Associated with All-Cause Mortality in Patients with Atrial Fibrillation: A Retrospective Study
Yuxuan Xu, Zhihui Lin, Chenxi Zhu, Dongyan Song, Bosen Wu, Kangting Ji & Jin Li
Pages: 691-700
Published online: 18 Feb 2023
AbstractforThe Neutrophil Percentage-to-Albumin Ratio is Associated with All-Cause Mortality in Patients with Atrial Fibrillation: A Retrospective Study | Full Text | References | PDF (2.9 MB) | EPUB
  • 263 Views
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Article
DNase I and Sivelestat Ameliorate Experimental Hindlimb Ischemia-Reperfusion Injury by Eliminating Neutrophil Extracellular Traps
Chun-Lian Wang, Yan Wang, Qi-Lan Jiang, Yang Zeng, Qing-Ping Yao, Xing Liu, Tao Li & Jun Jiang
Pages: 707-721
Published online: 21 Feb 2023
AbstractforDNase I and Sivelestat Ameliorate Experimental Hindlimb Ischemia-Reperfusion Injury by Eliminating Neutrophil Extracellular Traps | Full Text | References | PDF (14.2 MB) | EPUB
  • 295 Views
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Article
High Infiltration of CD203c+ Mast Cells Reflects Immunosuppression and Hinders Prognostic Benefit in Stage II-III Colorectal Cancer
Jing Li, Yuzhen Mo, Qingqing Wei, Jian Chen & Guozeng Xu
Pages: 723-735
Published online: 21 Feb 2023
AbstractforHigh Infiltration of CD203c+ Mast Cells Reflects Immunosuppression and Hinders Prognostic Benefit in Stage II-III Colorectal Cancer | Full Text | References | PDF (11.5 MB) | EPUB
  • 222 Views
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Article
Clinical Features of Crohn’s Disease Stratified by Age at Diagnosis According to Montreal Classification
Jiankang Xiang, Jiao Li, Chuan Liu, Shan Tian & Weiguo Dong
Pages: 737-746
Published online: 21 Feb 2023
AbstractforClinical Features of Crohn’s Disease Stratified by Age at Diagnosis According to Montreal Classification | Full Text | References | PDF (2.7 MB) | EPUB
  • 267 Views
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Article
Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma
Pengfei Wang, Xuxu Liu, Jingjing Yu, Ziang Meng, Zhenyi Lv, Ce Shang, Qi Geng, Dawei Wang, Dongbo Xue & Long Li
Pages: 747-768
Published online: 21 Feb 2023
AbstractforFucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma | Full Text | References | PDF (13.2 MB) | EPUB
  • 388 Views
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REVIEW

Review
ABO Blood Group and the Risk and Prognosis of Lymphoma
Ling Qin, Dongli Gao, Qian Wang, Xuewei Zheng, Jingjing Wang, Xingang Chen, Dongliao Fu, Haodi Ma, Junjia Tan & Qinan Yin
Pages: 769-778
Published online: 22 Feb 2023
AbstractforABO Blood Group and the Risk and Prognosis of Lymphoma | Full Text | References | PDF (1.7 MB) | EPUB
  • 339 Views
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ORIGINAL RESEARCH

Article
Efficacy of a Novel Pleiotropic MMP-Inhibitor, CMC2.24, in a Long-Term Diabetes Rat Model with Severe Hyperglycemia-Induced Oral Bone Loss
Heta Dinesh Bhatt, Lorne M Golub, Hsi-Ming Lee, Jihwan Kim, Thomas Zimmerman, Jie Deng, Houlin Hong, Francis Johnson & Ying Gu
Pages: 779-792
Published online: 23 Feb 2023
AbstractforEfficacy of a Novel Pleiotropic MMP-Inhibitor, CMC2.24, in a Long-Term Diabetes Rat Model with Severe Hyperglycemia-Induced Oral Bone Loss | Full Text | References | PDF (4.8 MB) | EPUB
  • 328 Views
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Article
Naples Prognostic Score as an Independent Predictor of Survival Outcomes for Resected Locally Advanced Non-Small Cell Lung Cancer Patients After Neoadjuvant Treatment
Zhonghua Zou, Jinping Li, Xiang Ji, Tingxing Wang, Qingqing Chen, Zhengcao Liu & Shengjun Ji
Pages: 793-807
Published online: 23 Feb 2023
AbstractforNaples Prognostic Score as an Independent Predictor of Survival Outcomes for Resected Locally Advanced Non-Small Cell Lung Cancer Patients After Neoadjuvant Treatment | Full Text | References | PDF (7.2 MB) | EPUB
  • 208 Views
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Article
Evaluation of Biomarkers from Peritoneal Fluid as Predictors of Severity for Abdominal Sepsis Patients Following Emergency Laparotomy
Jie Zhao, Teng Zhang, Zhe Deng, Xia Han, Tao Ma & Keliang Xie
Pages: 809-826
Published online: 24 Feb 2023
AbstractforEvaluation of Biomarkers from Peritoneal Fluid as Predictors of Severity for Abdominal Sepsis Patients Following Emergency Laparotomy | Full Text | References | PDF (8.6 MB) | EPUB
  • 320 Views
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Article
The SELP, CD93, IL2RG, and VAV1 Genes Associated with Atherosclerosis May Be Potential Diagnostic Biomarkers for Psoriasis
Shougang Liu, Fanghua Liu, Zeqiao Zhang, Zhe Zhuang, Xiuqing Yuan & Yongfeng Chen
Pages: 827-843
Published online: 27 Feb 2023
AbstractforThe SELP, CD93, IL2RG, and VAV1 Genes Associated with Atherosclerosis May Be Potential Diagnostic Biomarkers for Psoriasis | Full Text | References | PDF (8.9 MB) | EPUB
  • 347 Views
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Article
Neutrophil Extracellular Traps Induce Alveolar Macrophage Pyroptosis by Regulating NLRP3 Deubiquitination, Aggravating the Development of Septic Lung Injury
Yamei Cui, Ying Yang, Wenqiang Tao, Wei Peng, Deqiang Luo, Ning Zhao, Shuangyan Li, Kejian Qian & Fen Liu
Pages: 861-877
Published online: 27 Feb 2023
AbstractforNeutrophil Extracellular Traps Induce Alveolar Macrophage Pyroptosis by Regulating NLRP3 Deubiquitination, Aggravating the Development of Septic Lung Injury | Full Text | References | PDF (11.8 MB) | EPUB
  • 473 Views
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REVIEW

Review
Polarization Behavior of Bone Macrophage as Well as Associated Osteoimmunity in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
Qingyu Zhang, Wei Sun, Tengqi Li & Fanxiao Liu
Pages: 879-894
Published online: 28 Feb 2023
AbstractforPolarization Behavior of Bone Macrophage as Well as Associated Osteoimmunity in Glucocorticoid-Induced Osteonecrosis of the Femoral Head | Full Text | References | PDF (7.5 MB) | EPUB
  • 403 Views
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ORIGINAL RESEARCH

Article
A Novel Prognostic Marker and Therapeutic Target Associated with Glioma Progression in a Tumor Immune Microenvironment
Jun-Jie Zhang, Yu Zhang, Qian Chen, Qi-Ning Chen, Xin Yang, Xiao-Lin Zhu, Chun-Yan Hao & Hu-Bin Duan
Pages: 895-916
Published online: 01 Mar 2023
AbstractforA Novel Prognostic Marker and Therapeutic Target Associated with Glioma Progression in a Tumor Immune Microenvironment | Full Text | References | PDF (18.7 MB) | EPUB
  • 294 Views
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Article
Systemic Inflammatory Response Syndrome on Admission and Clinical Outcomes After Intracerebral Hemorrhage
Lijun Liu, Anxin Wang, Dandan Wang, Jiahuan Guo, Xiaoli Zhang, Xingquan Zhao & Wenjuan Wang
Pages: 917-926
Published online: 02 Mar 2023
AbstractforSystemic Inflammatory Response Syndrome on Admission and Clinical Outcomes After Intracerebral Hemorrhage | Full Text | References | PDF (3.7 MB) | EPUB
  • 195 Views
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REVIEW

Review
Tryptase and Exogenous Trypsin: Mechanisms and Ophthalmic Applications
Chao Ma, Haoyu Li, Shuwen Lu, Xian Li, Shuai Wang & Wenzhan Wang
Pages: 927-939
Published online: 02 Mar 2023
AbstractforTryptase and Exogenous Trypsin: Mechanisms and Ophthalmic Applications | Full Text | References | PDF (3 MB) | EPUB
  • 370 Views
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ORIGINAL RESEARCH

Article
Association of Systemic Immune Inflammation Index with All-Cause, Cardiovascular Disease, and Cancer-Related Mortality in Patients with Cardiovascular Disease: A Cross-Sectional Study
Shengjue Xiao, Zhenwei Wang, Ronghua Zuo, Yufei Zhou, Yiqing Yang, Tian Chen & Naifeng Liu
Pages: 941-961
Published online: 06 Mar 2023
AbstractforAssociation of Systemic Immune Inflammation Index with All-Cause, Cardiovascular Disease, and Cancer-Related Mortality in Patients with Cardiovascular Disease: A Cross-Sectional Study | Full Text | References | PDF (5.8 MB) | EPUB
  • 558 Views
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Article
Weighted Gene Co-Expression Network Analysis of Oxymatrine in Psoriasis Treatment
Xiaoxiao Xue, Yatao Guo, Qianying Zhao, Yongwen Li, Mi Rao, Wenjing Qi & Huijuan Shi
Pages: 845-859
Published online: 07 Mar 2023
AbstractforWeighted Gene Co-Expression Network Analysis of Oxymatrine in Psoriasis Treatment | Full Text | References | PDF (11.5 MB) | EPUB
  • 245 Views
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Article
ICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous- Carcinoma Immune Microenvironment
Yu Zhang, Xue-Li Wang, Jing-Jing Liu, Zhen-Yuan Qian, Zheng-Yang Pan, Ni-Ping Song, Hui-Yan Chen, Wei Zhang & Xin Zhang
Pages: 977-992
Published online: 07 Mar 2023
AbstractforICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous- Carcinoma Immune Microenvironment | Full Text | References | PDF (11 MB) | EPUB
  • 253 Views
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Article
The Systemic Inflammation Score is Associated with the Survival of Patients with Prostate Cancer
Jie Xie, Xu Xiao, Zhenjia Dong & Qiangdong Wang
Pages: 963-975
Published online: 07 Mar 2023
AbstractforThe Systemic Inflammation Score is Associated with the Survival of Patients with Prostate Cancer | Full Text | References | PDF (5.4 MB) | EPUB
  • 238 Views
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CORRIGENDUM

Correction
The Efficacy of Percutaneous Transhepatic Gallbladder Drainage Combined with Gallbladder-Preserving Cholecystolithotomy in High-Risk Patients with Acute Calculous Cholecystitis [Corrigendum]
Pages: 993-994
Published online: 08 Mar 2023
CitationforThe Efficacy of Percutaneous Transhepatic Gallbladder Drainage Combined with Gallbladder-Preserving Cholecystolithotomy in High-Risk Patients with Acute Calculous Cholecystitis [Corrigendum] | Full Text | PDF (233 KB) | EPUB
  • 127 Views
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ORIGINAL RESEARCH

Article
The Value of Peripheral Blood Cell Ratios in Primary Membranous Nephropathy: A Single Center Retrospective Study
Ai-Hua Zhang, Guang-Xia Dai, Qi-Dong Zhang, Hong-Dong Huang & Wen-Hu Liu
Pages: 1017-1025
Published online: 09 Mar 2023
AbstractforThe Value of Peripheral Blood Cell Ratios in Primary Membranous Nephropathy: A Single Center Retrospective Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 217 Views
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Article
Exploring Dysregulated Ferroptosis-Related Genes in Septic Myocardial Injury Based on Human Heart Transcriptomes: Evidence and New Insights
Hua-Xi Zou, Tie Hu, Jia-Yi Zhao, Bai-Quan Qiu, Chen-Chao Zou, Qi-Rong Xu, Ji-Chun Liu, Song-Qing Lai & Huang Huang
Pages: 995-1015
Published online: 09 Mar 2023
AbstractforExploring Dysregulated Ferroptosis-Related Genes in Septic Myocardial Injury Based on Human Heart Transcriptomes: Evidence and New Insights | Full Text | References | PDF (16.3 MB) | EPUB
  • 295 Views
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Article
Pretreatment with Eupatilin Attenuates Inflammation and Coagulation in Sepsis by Suppressing JAK2/STAT3 Signaling Pathway
Yilun Lu, Ding Li, Yueyue Huang, Yuanyuan Sun, Hongmin Zhou, Fanrong Ye, Hongjing Yang, Tingting Xu, Shichao Quan & Jingye Pan
Pages: 1027-1042
Published online: 10 Mar 2023
AbstractforPretreatment with Eupatilin Attenuates Inflammation and Coagulation in Sepsis by Suppressing JAK2/STAT3 Signaling Pathway | Full Text | References | PDF (9.3 MB) | EPUB
  • 320 Views
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CORRIGENDUM

Correction
The Differential Expression of the Inflammasomes in Adipose Tissue and Colon Influences the Development of Colon Cancer in a Context of Obesity by Regulating Intestinal Inflammation [Corrigendum]
Pages: 1043-1044
Published online: 11 Mar 2023
CitationforThe Differential Expression of the Inflammasomes in Adipose Tissue and Colon Influences the Development of Colon Cancer in a Context of Obesity by Regulating Intestinal Inflammation [Corrigendum] | Full Text | PDF (234.3 KB) | EPUB
  • 138 Views
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ORIGINAL RESEARCH

Article
Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway
Jiao Ma, Zhuoxiao Han, Rui Jiao, Guanli Yuan, Cuiqing Ma, Xixin Yan & Aihong Meng
Pages: 1045-1057
Published online: 11 Mar 2023
AbstractforIrisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway | Full Text | References | PDF (8.3 MB) | EPUB
  • 278 Views
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Article
Nomogram Based on Preoperative Fibrinogen and Systemic Immune-Inflammation Index Predicting Recurrence and Prognosis of Patients with Borrmann Type III Advanced Gastric Cancer
Hao Wang, Xin Yin, Keru Ma, Yufei Wang, Tianyi Fang, Yao Zhang & Yingwei Xue
Pages: 1059-1075
Published online: 12 Mar 2023
AbstractforNomogram Based on Preoperative Fibrinogen and Systemic Immune-Inflammation Index Predicting Recurrence and Prognosis of Patients with Borrmann Type III Advanced Gastric Cancer | Full Text | References | PDF (8.3 MB) | EPUB
  • 202 Views
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Article
Risk Genetic Variants (IL-10) for Osteoporosis in Han Population from Northwest China
Kai Rong, Yi Lang, Yubo Zhou, Liangtao Ni, Lei Wang, Long Wang, Yaowu Zhang, Fengli Wen, Zhan Wang & Pingbo Chen
Pages: 1091-1102
Published online: 14 Mar 2023
AbstractforRisk Genetic Variants (IL-10) for Osteoporosis in Han Population from Northwest China | Full Text | References | PDF (1.3 MB) | EPUB
  • 221 Views
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Article
Common Variables That Influence Sepsis Mortality in Mice
Luiz F Garcia, Vishwajeet Singh, Blake Mireles, Alok Kumar Dwivedi & Wendy E Walker
Pages: 1121-1134
Published online: 14 Mar 2023
AbstractforCommon Variables That Influence Sepsis Mortality in Mice | Full Text | References | PDF (5.3 MB) | EPUB
  • 356 Views
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Article
Association Between Salivary Cytokines, Chemokines and Growth Factors and Salivary Gland Function in Children with Chronic Kidney Disease
Julita Szulimowska, Anna Zalewska, Katarzyna Taranta-Janusz, Grażyna Marczuk-Kolada, Małgorzata Żendzian-Piotrowska & Mateusz Maciejczyk
Pages: 1103-1120
Published online: 14 Mar 2023
AbstractforAssociation Between Salivary Cytokines, Chemokines and Growth Factors and Salivary Gland Function in Children with Chronic Kidney Disease | Full Text | References | PDF (4.7 MB) | EPUB
  • 398 Views
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Article
miR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes
Yongquan Chen, Yecheng Deng, Linghua Chen, Ziyao Huang, Yi Yan & Zhaoqi Huang
Pages: 1077-1089
Published online: 14 Mar 2023
AbstractformiR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes | Full Text | References | PDF (10.5 MB) | EPUB
  • 247 Views
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Article
Biomarkers for Lipid and Albumin Metabolism in Hospitalized Patients with Underlying Diseases and Community-Acquired Pneumonia Caused by Bacterial or SARS-CoV-2 Infection
Zheng Liu, Qian Wang, Hui Wang, Jing Li, Ying Yuan & Guo-zhen Yi
Pages: 1135-1145
Published online: 15 Mar 2023
AbstractforBiomarkers for Lipid and Albumin Metabolism in Hospitalized Patients with Underlying Diseases and Community-Acquired Pneumonia Caused by Bacterial or SARS-CoV-2 Infection | Full Text | References | PDF (2.5 MB) | EPUB
  • 256 Views
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Article
Correlations Between Inflammatory Cell Infiltration and Relative Density and the Boundary Manifestation of Pulmonary Non-Neoplastic Ground Glass Nodules
Xiang-Ling Liu, Fa-Jin Lv, Bin-Jie Fu, Rui-Yu Lin, Wang-Jia Li & Zhi-Gang Chu
Pages: 1147-1155
Published online: 15 Mar 2023
AbstractforCorrelations Between Inflammatory Cell Infiltration and Relative Density and the Boundary Manifestation of Pulmonary Non-Neoplastic Ground Glass Nodules | Full Text | References | PDF (743.3 KB) | EPUB
  • 179 Views
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SHORT REPORT

Predictive Risk Factors of Pancreatic Exocrine Insufficiency Developed After Acute Pancreatitis: A Retrospective Cohort Study
Yulin Guo, Xiaohui Wang, Shuo Wang, Ang Li, Feng Cao & Fei Li
Pages: 1157-1167
Published online: 15 Mar 2023
AbstractforPredictive Risk Factors of Pancreatic Exocrine Insufficiency Developed After Acute Pancreatitis: A Retrospective Cohort Study | Full Text | References | PDF (486.2 KB) | EPUB
  • 316 Views
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ORIGINAL RESEARCH

Article
Time-Series Expression Profile Analysis of Post-Traumatic Joint Contracture in Rats at the Early Stages of the Healing Process
Yuxin Zhang, Zhigang Wu, Shenji Lu, Minghui Lin, Xiaokun Yue, Zengguang Wang & Bin Cai
Pages: 1169-1181
Published online: 15 Mar 2023
AbstractforTime-Series Expression Profile Analysis of Post-Traumatic Joint Contracture in Rats at the Early Stages of the Healing Process | Full Text | References | PDF (6.6 MB) | EPUB
  • 241 Views
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Article
Predictive Value of Serum Heat Shock Protein 90α on the Prognosis of Patients with Lung Adenocarcinoma
Yue Fang, Zhichao Yuan, Hao Zhang, Peng Wang & Jiqing Hao
Pages: 1183-1193
Published online: 16 Mar 2023
AbstractforPredictive Value of Serum Heat Shock Protein 90α on the Prognosis of Patients with Lung Adenocarcinoma | Full Text | References | PDF (1.6 MB) | EPUB
  • 192 Views
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REVIEW

Review
Metabolic Reprogramming and Its Regulatory Mechanism in Sepsis-Mediated Inflammation
Wenzhang Liu, Tianyi Liu, Yongjun Zheng & Zhaofan Xia
Pages: 1195-1207
Published online: 20 Mar 2023
AbstractforMetabolic Reprogramming and Its Regulatory Mechanism in Sepsis-Mediated Inflammation | Full Text | References | PDF (1.8 MB) | EPUB
  • 511 Views
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ORIGINAL RESEARCH

Article
Circulating Leukocyte as an Inflammatory Biomarker: Association with Fibrinogen and Neuronal Damage in Acute Ischemic Stroke
Lu Han, Ze Wang, Jian Yuan, Jun He, Yun Deng, De-Sheng Zhu & Yang-Tai Guan
Pages: 1213-1226
Published online: 21 Mar 2023
AbstractforCirculating Leukocyte as an Inflammatory Biomarker: Association with Fibrinogen and Neuronal Damage in Acute Ischemic Stroke | Full Text | References | PDF (6.3 MB) | EPUB
  • 326 Views
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Other

IL-34 and Immune Checkpoint Inhibitors Resistant through Macrophages: Pan-Cancer Overview
Mohammed Safi, Al-shaebi Fadhl, Yousif A Algabri & Caiqing Zhang
Pages: 1209-1212
Published online: 21 Mar 2023
First Page PreviewforIL-34 and Immune Checkpoint Inhibitors Resistant through Macrophages: Pan-Cancer Overview | Full Text | References | PDF (3.5 MB) | EPUB
  • 299 Views
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ORIGINAL RESEARCH

Article
Prognostic Value of Pentraxin-3 Change After Primary Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction
Sheng-Yu Li, Lei Liu, Ding-Kun Wang, Xiao-Song Ding, Wei-Ping Li & Hong-Wei Li
Pages: 1255-1266
Published online: 22 Mar 2023
AbstractforPrognostic Value of Pentraxin-3 Change After Primary Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction | Full Text | References | PDF (5.3 MB) | EPUB
  • 189 Views
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Article
Perinatal Infection with Listeria monocytogenes: A 10-Year Hospital-Based Study in Western China
Yongchi Zhan, Tingting Xu, Hongyan Liu, Xiaodong Wang & Haiyan Yu
Pages: 1243-1254
Published online: 22 Mar 2023
AbstractforPerinatal Infection with Listeria monocytogenes: A 10-Year Hospital-Based Study in Western China | Full Text | References | PDF (485.8 KB) | EPUB
  • 396 Views
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Article
Development of Nomogram Models Based on Peripheral Blood Score and Clinicopathological Parameters to Predict Preoperative Advanced Stage and Prognosis for Epithelial Ovarian Cancer Patients
Gaigai Bai, Yue Zhou, Qing Rong, Sijing Qiao, Hongluan Mao & Peishu Liu
Pages: 1227-1241
Published online: 23 Mar 2023
AbstractforDevelopment of Nomogram Models Based on Peripheral Blood Score and Clinicopathological Parameters to Predict Preoperative Advanced Stage and Prognosis for Epithelial Ovarian Cancer Patients | Full Text | References | PDF (1.4 MB) | EPUB
  • 232 Views
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CASE REPORT

Case Report
Case Report: Unusual Cause of Fever in Ulcerative Colitis Treated with Infliximab
Sumei Sha, Haitao Shi, Jie Wu, Ming Zhang, Bin Qin, Longbao Yang & Xin Liu
Pages: 1267-1270
Published online: 23 Mar 2023
AbstractforCase Report: Unusual Cause of Fever in Ulcerative Colitis Treated with Infliximab | Full Text | References | PDF (2.2 MB) | EPUB
  • 178 Views
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ORIGINAL RESEARCH

Article
PINK1/Parkin-Mediated Mitochondrial Autophagy Participates in H2O2-Induced Abnormal Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
Gaoyuan Wang, Xiaoyu Chen, Yubao Shao & Bin Xu
Pages: 1271-1282
Published online: 23 Mar 2023
AbstractforPINK1/Parkin-Mediated Mitochondrial Autophagy Participates in H2O2-Induced Abnormal Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis | Full Text | References | PDF (9.7 MB) | EPUB
  • 336 Views
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REVIEW

Review
Possible Future Avenues for Rheumatoid Arthritis Therapeutics: Hippo Pathway
Tao Wang, Zhandong Wang, Wenxia Qi, Ganggang Jiang & Gang Wang
Pages: 1283-1296
Published online: 24 Mar 2023
AbstractforPossible Future Avenues for Rheumatoid Arthritis Therapeutics: Hippo Pathway | Full Text | References | PDF (3.9 MB) | EPUB
  • 286 Views
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ORIGINAL RESEARCH

Article
Serum Amyloid a Predicts Prognosis and Chemotherapy Efficacy in Patients with Advanced Pancreatic Cancer
Honglu Ding, Qiuxia Yang, Yize Mao, Dailei Qin, Zehui Yao, Ruiqi Wang, Tao Qin & Shengping Li
Pages: 1297-1310
Published online: 24 Mar 2023
AbstractforSerum Amyloid a Predicts Prognosis and Chemotherapy Efficacy in Patients with Advanced Pancreatic Cancer | Full Text | References | PDF (8 MB) | EPUB
  • 249 Views
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Article
circHECTD1 Promotes the Proliferation and Migration of Human Brain Vascular Smooth Muscle Cells via Interacting with KHDRBS3 to Stabilize EZH2 mRNA Expression
Meina Feng, Wenxian Tu, Qin Zhou, Yuanmin Du, Kang Xu & Yunfeng Wang
Pages: 1311-1323
Published online: 24 Mar 2023
AbstractforcircHECTD1 Promotes the Proliferation and Migration of Human Brain Vascular Smooth Muscle Cells via Interacting with KHDRBS3 to Stabilize EZH2 mRNA Expression | Full Text | References | PDF (11.9 MB) | EPUB
  • 371 Views
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Article
Association of the Systemic Immune-Inflammation Index with Outcomes in Acute Coronary Syndrome Patients with Chronic Kidney Disease
Sanling Shi, Shuting Kong, Weicheng Ni, Yucheng Lu, Junfeng Li, Yuheng Huang, Jinxin Chen, Ken Lin, Yuanmiao Li, Jiayu Ke & Hao Zhou
Pages: 1343-1356
Published online: 27 Mar 2023
AbstractforAssociation of the Systemic Immune-Inflammation Index with Outcomes in Acute Coronary Syndrome Patients with Chronic Kidney Disease | Full Text | References | PDF (4.9 MB) | EPUB
  • 390 Views
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Article
Overexpression of TREM1 is Associated with the Immune-Suppressive Microenvironment and Unfavorable Prognosis in Pan-Cancer
Xinwei Zhou, Ke Lin, Liangmin Fu, Fei Liu, Hansen Lin, Yuhang Chen, Bowen Zhuang, Hui Liang, Qiong Deng, Zhu Wang, Wei Chen, Junhang Luo, Jiazheng Cao & Pengju Li
Pages: 1375-1391
Published online: 27 Mar 2023
AbstractforOverexpression of TREM1 is Associated with the Immune-Suppressive Microenvironment and Unfavorable Prognosis in Pan-Cancer | Full Text | References | PDF (15.4 MB) | EPUB
  • 363 Views
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Article
Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation
Xiangyu Su, Guoqing Wang, Shiya Zheng, Chang Ge, Fei Kong & Cailian Wang
Pages: 1325-1342
Published online: 27 Mar 2023
AbstractforComprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation | Full Text | References | PDF (17.7 MB) | EPUB
  • 201 Views
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Article
Metabolomic Profiling of Lungs from Mice Reveals the Variability of Metabolites in Pneumocystis Infection and the Metabolic Abnormalities in BAFF-R-Deficient Mice
Heng-Mo Rong, Han-Yu-Jie Kang & Zhao-Hui Tong
Pages: 1357-1373
Published online: 27 Mar 2023
AbstractforMetabolomic Profiling of Lungs from Mice Reveals the Variability of Metabolites in Pneumocystis Infection and the Metabolic Abnormalities in BAFF-R-Deficient Mice | Full Text | References | PDF (9 MB) | EPUB
  • 220 Views
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Article
Bifidobacterium longum Administration Diminishes Parasitemia and Inflammation During Plasmodium berghei Infection in Mice
Loeki Enggar Fitri, Teguh Wahju Sardjono, Nuning Winaris, Aulia Rahmi Pawestri, Agustina Tri Endharti, Eviana Norahmawati, Dian Handayani, Shahdevi Nandar Kurniawan, Syafiatul Azizah, Lustyafa Inassani Alifia, Rokhmatul Asiyah & Tita Rachma Ayuningtyas
Pages: 1393-1404
Published online: 27 Mar 2023
AbstractforBifidobacterium longum Administration Diminishes Parasitemia and Inflammation During Plasmodium berghei Infection in Mice | Full Text | References | PDF (5.6 MB) | EPUB
  • 396 Views
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REVIEW

Review
MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury
Bo Yu, Yalong Zhang, Tianyu Wang, Jiayu Guo, Chenyang Kong, Zhongbao Chen, Xiaoxiong Ma & Tao Qiu
Pages: 1405-1418
Published online: 27 Mar 2023
AbstractforMAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury | Full Text | References | PDF (1.1 MB) | EPUB
  • 320 Views
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ORIGINAL RESEARCH

Article
Association of Neutrophil-to-Lymphocyte Ratio with Nutrition in Patients with Various Types of Malignant Tumors: A Multicenter Cross-Sectional Study
Lihua Kang, Xiangliang Liu, Wei Ji, Kaiwen Zheng, Yuguang Li, Yanqiu Song, Hua He, Xiaomeng Wang, Tingting Yang, Meng Guan, Ge Zhu, Yangyang Gao, Yanjie Guan, Lei Wang & Wei Li
Pages: 1419-1429
Published online: 27 Mar 2023
AbstractforAssociation of Neutrophil-to-Lymphocyte Ratio with Nutrition in Patients with Various Types of Malignant Tumors: A Multicenter Cross-Sectional Study | Full Text | References | PDF (1.6 MB) | EPUB
  • 259 Views
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CASE SERIES

Case Report
Spontaneous Pneumomediastinum and Subcutaneous Emphysema in Dermatomyositis: A Case Series and Literature Review
Ahmed Hussein Subki, Ibraheem Mohammed Almani, Abdurahman Albeity, Bandari Khalid Aljabri, Roaa Alsolaimani & Hussein Halabi
Pages: 1431-1441
Published online: 03 Apr 2023
AbstractforSpontaneous Pneumomediastinum and Subcutaneous Emphysema in Dermatomyositis: A Case Series and Literature Review | Full Text | References | PDF (837.6 KB) | EPUB
  • 316 Views
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REVIEW

Review
Mitophagy, Inflammasomes and Their Interaction in Kidney Diseases: A Comprehensive Review of Experimental Studies
Yulin Wang, Dongxu Song & Lin Tang
Pages: 1457-1469
Published online: 05 Apr 2023
AbstractforMitophagy, Inflammasomes and Their Interaction in Kidney Diseases: A Comprehensive Review of Experimental Studies | Full Text | References | PDF (1.9 MB) | EPUB
  • 258 Views
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ORIGINAL RESEARCH

Article
A Novel Predictor of Pathologic Complete Response for Neoadjuvant Immunochemotherapy in Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
Yalan Yang, Dao Xin, Huike Wang, Lulu Guan, Xiangrui Meng, Taiying Lu, Xiwen Bai & Feng Wang
Pages: 1443-1455
Published online: 05 Apr 2023
AbstractforA Novel Predictor of Pathologic Complete Response for Neoadjuvant Immunochemotherapy in Resectable Locally Advanced Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (4.2 MB) | EPUB
  • 199 Views
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Review

Review
Potential Use of Janus Kinase Inhibitors in the Treatment of Systemic Lupus Erythematosus
Rongxiu Huo, Xinxiang Huang, Yang Yang & Jinying Lin
Pages: 1471-1478
Published online: 06 Apr 2023
AbstractforPotential Use of Janus Kinase Inhibitors in the Treatment of Systemic Lupus Erythematosus | Full Text | References | PDF (1.7 MB) | EPUB
  • 377 Views
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ORIGINAL RESEARCH

Article
Protective Effect of Qingchang Wenzhong Decoction on Colitis and Colitis-Related Carcinogenesis by Regulating Inflammation and Intestinal Fibrosis
Yuan Cheng, Junxiang Li, Xiaosi Zhang, Yalan Li, Xiaojun Shi, Rui Shi, Tangyou Mao, Fushun Kou & Lei Shi
Pages: 1479-1495
Published online: 07 Apr 2023
AbstractforProtective Effect of Qingchang Wenzhong Decoction on Colitis and Colitis-Related Carcinogenesis by Regulating Inflammation and Intestinal Fibrosis | Full Text | References | PDF (15 MB) | EPUB
  • 231 Views
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Article
Dental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress
Xiaoli Gao, Zhiqiang Liu & Zuomin Wang
Pages: 1497-1508
Published online: 08 Apr 2023
AbstractforDental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress | Full Text | References | PDF (8 MB) | EPUB
  • 300 Views
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Article
C-Terminal Fibronectin Exerts Beneficial Effects in Reducing Tissue Damage and Modulating Macrophage Function in a Murine Septic Model
Haili Geng, Yong Wu & Yuanzhong Chen
Pages: 1509-1521
Published online: 10 Apr 2023
AbstractforC-Terminal Fibronectin Exerts Beneficial Effects in Reducing Tissue Damage and Modulating Macrophage Function in a Murine Septic Model | Full Text | References | PDF (4.5 MB) | EPUB
  • 210 Views
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LETTER

Letter to the Editor
Can Post-Menopausal Osteoporosis Be Prevented by Essential Fatty Acids? [Letter]
Undurti N Das
Pages: 1553-1554
Published online: 12 Apr 2023
CitationforCan Post-Menopausal Osteoporosis Be Prevented by Essential Fatty Acids? [Letter] | Full Text | References | PDF (277.6 KB) | EPUB
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ORIGINAL RESEARCH

Article
Construction of the Interaction Network of Hub Genes in the Progression of Barrett’s Esophagus to Esophageal Adenocarcinoma
Kai Li, Peipei Duan, Haifa He, Ruijuan Du, Qian Wang, Pengju Gong & Hua Bian
Pages: 1533-1551
Published online: 12 Apr 2023
AbstractforConstruction of the Interaction Network of Hub Genes in the Progression of Barrett’s Esophagus to Esophageal Adenocarcinoma | Full Text | References | PDF (19.2 MB) | EPUB
  • 253 Views
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REVIEW

Review
PANoptosis: A Cell Death Characterized by Pyroptosis, Apoptosis, and Necroptosis
Chunxia Shi, Pan Cao, Yukun Wang, Qingqi Zhang, Danmei Zhang, Yao Wang, Luwen Wang & Zuojiong Gong
Pages: 1523-1532
Published online: 12 Apr 2023
AbstractforPANoptosis: A Cell Death Characterized by Pyroptosis, Apoptosis, and Necroptosis | Full Text | References | PDF (1.5 MB) | EPUB
  • 606 Views
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ORIGINAL RESEARCH

Article
Identification of Potential Diagnostic Genes of HIV-Infected Immunological Non-Responders on Bioinformatics Analysis
Yanhong Ding, Cheng Pu, Xiao Zhang, Gaoyan Tang, Fengjuan Zhang & Guohua Yu
Pages: 1555-1570
Published online: 14 Apr 2023
AbstractforIdentification of Potential Diagnostic Genes of HIV-Infected Immunological Non-Responders on Bioinformatics Analysis | Full Text | References | PDF (12 MB) | EPUB
  • 305 Views
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Article
Ge-Gen Decoction Exerts an Anti-Primary Dysmenorrhea Effect in Rats by Inactivating the HSP90/NLRP3/NF-κB/COX-2 Pathway
Yazhen Xie & Jianqiang Qian
Pages: 1571-1580
Published online: 15 Apr 2023
AbstractforGe-Gen Decoction Exerts an Anti-Primary Dysmenorrhea Effect in Rats by Inactivating the HSP90/NLRP3/NF-κB/COX-2 Pathway | Full Text | References | PDF (6.9 MB) | EPUB
  • 207 Views
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Article
The Relationship Between the Neutrophil Percentage-to-Albumin Ratio and Rates of 28-Day Mortality in Atrial Fibrillation Patients 80 Years of Age or Older
Jiasheng Cai, Mingxuan Li, Wei Wang, Rong Luo, Zheng Zhang & Haibo Liu
Pages: 1629-1638
Published online: 17 Apr 2023
AbstractforThe Relationship Between the Neutrophil Percentage-to-Albumin Ratio and Rates of 28-Day Mortality in Atrial Fibrillation Patients 80 Years of Age or Older | Full Text | References | PDF (2.4 MB) | EPUB
  • 203 Views
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Article
Systemic Immune-Inflammation Index and Long-Term Mortality in Patients with Stroke-Associated Pneumonia
Mengdi Xie, Kang Yuan, Xinyi Zhu, Jingjing Chen, Xiaohao Zhang, Yi Xie, Min Wu, Zhaojun Wang, Rui Liu & Xinfeng Liu
Pages: 1581-1593
Published online: 17 Apr 2023
AbstractforSystemic Immune-Inflammation Index and Long-Term Mortality in Patients with Stroke-Associated Pneumonia | Full Text | References | PDF (4 MB) | EPUB
  • 281 Views
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Article
Electroacupuncture Pretreatment at Zusanli (ST36) Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice by Reducing Oxidative Stress via Activating Vagus Nerve-Dependent Nrf2 Pathway
Haochen Jiang, Zhi Shang, Liping You, Jinghao Zhang, Junzhe Jiao, Yihan Qian, Jiacheng Lin, Fang Wang, Yueqiu Gao, Xiaoni Kong & Xuehua Sun
Pages: 1595-1610
Published online: 17 Apr 2023
AbstractforElectroacupuncture Pretreatment at Zusanli (ST36) Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice by Reducing Oxidative Stress via Activating Vagus Nerve-Dependent Nrf2 Pathway | Full Text | References | PDF (12.6 MB) | EPUB
  • 272 Views
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Article
Identification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA
Yifan Yuan, Na Li, Mingyue Fu & Mei Ye
Pages: 1611-1628
Published online: 17 Apr 2023
AbstractforIdentification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA | Full Text | References | PDF (13.3 MB) | EPUB
  • 307 Views
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REVIEW

Review
Research Progress on Autophagy Regulation by Active Ingredients of Traditional Chinese Medicine in the Treatment of Acute Lung Injury
Jin-yan Dong, Hong-Lin Yin, Hao Hao & Yang Liu
Pages: 1671-1691
Published online: 17 Apr 2023
AbstractforResearch Progress on Autophagy Regulation by Active Ingredients of Traditional Chinese Medicine in the Treatment of Acute Lung Injury | Full Text | References | PDF (5.2 MB) | EPUB
  • 335 Views
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ORIGINAL RESEARCH

Article
Mutations Status of NOTCH Signaling Pathway Predict Prognosis of Immune Checkpoint Inhibitors in Colorectal Cancer
Anqi Lin, Jiarong Yao, Quan Cheng, Zaoqu Liu, Peng Luo & Jian Zhang
Pages: 1693-1709
Published online: 17 Apr 2023
AbstractforMutations Status of NOTCH Signaling Pathway Predict Prognosis of Immune Checkpoint Inhibitors in Colorectal Cancer | Full Text | References | PDF (6.2 MB) | EPUB
  • 314 Views
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Article
Utilizing the Lactate Dehydrogenase-to-Albumin Ratio for Survival Prediction in Patients with Bladder Cancer After Radical Cystectomy
Hang Xu, Tianhai Lin, Jianzhong Ai, Jiapeng Zhang, Shiyu Zhang, Yifan Li, Xiaonan Zheng, Peng Zhang, Qiang Wei, Ping Tan & Lu Yang
Pages: 1733-1744
Published online: 18 Apr 2023
AbstractforUtilizing the Lactate Dehydrogenase-to-Albumin Ratio for Survival Prediction in Patients with Bladder Cancer After Radical Cystectomy | Full Text | References | PDF (534.4 KB) | EPUB
  • 243 Views
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Article
CD8A is a Promising Biomarker Associated with Immunocytes Infiltration in Hyperoxia-Induced Bronchopulmonary Dysplasia
Yiting Du, Limin Zuo, Ying Xiong, Xuedong Wang, Jun Zou & Hong Xu
Pages: 1653-1669
Published online: 17 Apr 2023
AbstractforCD8A is a Promising Biomarker Associated with Immunocytes Infiltration in Hyperoxia-Induced Bronchopulmonary Dysplasia | Full Text | References | PDF (15.5 MB) | EPUB
  • 222 Views
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Article
Diminazene Ameliorates Neuroinflammation by Suppression of Astrocytic miRNA-224-5p/NLRP3 Axis in Alzheimer’s Disease Model
XiaoJin Sun, Yang Deng, PengXin Ge, Qiang Peng, Ismatullah Soufiany, Lin Zhu & Rui Duan
Pages: 1639-1652
Published online: 17 Apr 2023
AbstractforDiminazene Ameliorates Neuroinflammation by Suppression of Astrocytic miRNA-224-5p/NLRP3 Axis in Alzheimer’s Disease Model | Full Text | References | PDF (8.3 MB) | EPUB
  • 267 Views
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CASE REPORT

Case Report
Immune-Related Colitis Induced by Camrelizumab: A Case Report
Sheng Cheng, Yun Yang, Junxian Yu, Wei Chen & Xingang Li
Pages: 1727-1731
Published online: 18 Apr 2023
AbstractforImmune-Related Colitis Induced by Camrelizumab: A Case Report | Full Text | References | PDF (545.2 KB) | EPUB
  • 168 Views
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ORIGINAL RESEARCH

Article
Expression Profile of Pyroptosis-Related Genes and the Associated Regulatory Axis in Primary Gout Patients
Shaowei Niu, Tian-Yi Lei, Fei Dai, Hongyuan Xie, Xiang Yu, Quanbo Zhang & Yufeng Qing
Pages: 1711-1725
Published online: 19 Apr 2023
AbstractforExpression Profile of Pyroptosis-Related Genes and the Associated Regulatory Axis in Primary Gout Patients | Full Text | References | PDF (11.3 MB) | EPUB
  • 239 Views
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LETTER

Letter to the Editor
Preclinical Model in Sepsis: Should We Abandon the CLP? [Letter]
Jeremie Joffre
Pages: 1757-1759
Published online: 21 Apr 2023
First Page PreviewforPreclinical Model in Sepsis: Should We Abandon the CLP? [Letter] | Full Text | References | PDF (1.3 MB) | EPUB
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ORIGINAL RESEARCH

Article
Dynamic Change of Novel Systemic Inflammation Markers to Predict Maternal-Neonatal Prognosis After Cervical Cerclage
Yan Lin, Jiaoning Fang, Ruilan Ni, Li Zhang, Jie Zhao, Xiumin Jiang, Yuping Lin & Mian Pan
Pages: 1745-1756
Published online: 21 Apr 2023
AbstractforDynamic Change of Novel Systemic Inflammation Markers to Predict Maternal-Neonatal Prognosis After Cervical Cerclage | Full Text | References | PDF (2.7 MB) | EPUB
  • 272 Views
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Article
Nomogram Based on Preoperative Absolute Lymphocyte Count to Predict Local Recurrence in Patients with Non-Small Cell Lung Cancer After Microwave Ablation
Yonghui Lv, Yuanwei Liu, Kaiguo Li, Zhiling Liu, Tong Zhang, Mingguang Duan, Yunchao Chen, Teng Ma, Guanghui Huang & Zhaoqin Huang
Pages: 1761-1770
Published online: 21 Apr 2023
AbstractforNomogram Based on Preoperative Absolute Lymphocyte Count to Predict Local Recurrence in Patients with Non-Small Cell Lung Cancer After Microwave Ablation | Full Text | References | PDF (5.1 MB) | EPUB
  • 198 Views
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Article
Joint Application of Multiple Inflammatory Cytokines in Diagnosis of Gout Flare
Hanqing Yu, Wen Xue, Hanjie Yu, Hongchen Gu, Ling Qin & Ai Peng
Pages: 1771-1782
Published online: 21 Apr 2023
AbstractforJoint Application of Multiple Inflammatory Cytokines in Diagnosis of Gout Flare | Full Text | References | PDF (4.4 MB) | EPUB
  • 257 Views
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Article
Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma
Bowen Li, Jinghang Liu, Liangzhi Xu, Qi Xu, Zhaohui Liu & Tiande Liu
Pages: 1783-1804
Published online: 21 Apr 2023
AbstractforComprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma | Full Text | References | PDF (15.1 MB) | EPUB
  • 245 Views
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REVIEW

Review
The Involvement of Glucose and Lipid Metabolism Alteration in Rheumatoid Arthritis and Its Clinical Implication
Ting-Ting Luo, Yi-Jin Wu, Qin Yin, Wen-Gang Chen & Jian Zuo
Pages: 1837-1852
Published online: 26 Apr 2023
AbstractforThe Involvement of Glucose and Lipid Metabolism Alteration in Rheumatoid Arthritis and Its Clinical Implication | Full Text | References | PDF (2.1 MB) | EPUB
  • 332 Views
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ORIGINAL RESEARCH

Article
Identification of Ferroptosis-Related Biomarkers for Diagnosis and Molecular Classification of Staphylococcus aureus-Induced Osteomyelitis
Xiangwen Shi, Linmeng Tang, Haonan Ni, Mingjun Li, Yipeng Wu & Yongqing Xu
Pages: 1805-1823
Published online: 26 Apr 2023
AbstractforIdentification of Ferroptosis-Related Biomarkers for Diagnosis and Molecular Classification of Staphylococcus aureus-Induced Osteomyelitis | Full Text | References | PDF (16.8 MB) | EPUB
  • 302 Views
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Article
Association of Serum Uric Acid Level with Risk of Abdominal Aortic Calcification: A Large Cross-Sectional Study
Tao Liu, Ronghua Zuo, Jia Song, Jia Wang, Zhijian Zhu, Lifang Sun, Shasha Wang, Baoyin Li, Yesheng Pan & Bing Wang
Pages: 1825-1836
Published online: 26 Apr 2023
AbstractforAssociation of Serum Uric Acid Level with Risk of Abdominal Aortic Calcification: A Large Cross-Sectional Study | Full Text | References | PDF (850.5 KB) | EPUB
  • 221 Views
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Article
Association of Neutrophil to High-Density Lipoprotein Cholesterol Ratio with Cardiac Ultrasound Parameters and Cardiovascular Risk: A Cross-Sectional Study Based on Healthy Populations
Xiaoyu Pan, Xueqing Zhang, Jiangli Ban, Lin Yue, Lin Ren & Shuchun Chen
Pages: 1853-1865
Published online: 27 Apr 2023
AbstractforAssociation of Neutrophil to High-Density Lipoprotein Cholesterol Ratio with Cardiac Ultrasound Parameters and Cardiovascular Risk: A Cross-Sectional Study Based on Healthy Populations | Full Text | References | PDF (6.1 MB) | EPUB
  • 247 Views
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Article
SARS-CoV-2 N Protein Triggers Acute Lung Injury via Modulating Macrophage Activation and Infiltration in in vitro and in vivo
Dengming Lai, Kun Zhu, Sisi Li, Yi Xiao, Qi Xu, Yisheng Sun, Pingping Yao, Daqing Ma & Qiang Shu
Pages: 1867-1877
Published online: 28 Apr 2023
AbstractforSARS-CoV-2 N Protein Triggers Acute Lung Injury via Modulating Macrophage Activation and Infiltration in in vitro and in vivo | Full Text | References | PDF (5.3 MB) | EPUB
  • 254 Views
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Article
A Novel Nomogram Combining Mucus Barrier Index for Predicting Treatment Failures in Ulcerative Colitis
Ying Wang, Xuanzhi Huang, Gaoshi Zhou, Jing Han, Zhuo Xie, Mudan Zhang, Xiaoling Li, Qi-rui Wu, Li Li, Ziyin Ye, Minhu Chen, Yun Qiu & Shenghong Zhang
Pages: 1879-1894
Published online: 01 May 2023
AbstractforA Novel Nomogram Combining Mucus Barrier Index for Predicting Treatment Failures in Ulcerative Colitis | Full Text | References | PDF (9.4 MB) | EPUB
  • 167 Views
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Article
Platelet-to-Lymphocyte Ratio (PLR) as the Prognostic Factor for Recurrence/Residual Disease in HSIL Patients After LEEP
Guanxiang Huang, Hangjing Gao, Yanlin Chen, Wenyu Lin, Jun Shen, Shuxia Xu, Dabin Liu, Zhihui Wu, Xite Lin, Tingting Jiang, Binhua Dong & Pengming Sun
Pages: 1923-1936
Published online: 01 May 2023
AbstractforPlatelet-to-Lymphocyte Ratio (PLR) as the Prognostic Factor for Recurrence/Residual Disease in HSIL Patients After LEEP | Full Text | References | PDF (5.6 MB) | EPUB
  • 285 Views
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REVIEW

Review
Long-Term Effects of Severe Burns on the Kidneys: Research Advances and Potential Therapeutic Approaches
Guang Yang, Lishan Tan, Hua Yao, Zuying Xiong, Jun Wu & Xiaoyan Huang
Pages: 1905-1921
Published online: 01 May 2023
AbstractforLong-Term Effects of Severe Burns on the Kidneys: Research Advances and Potential Therapeutic Approaches | Full Text | References | PDF (4.2 MB) | EPUB
  • 509 Views
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ORIGINAL RESEARCH

Article
The Gut Microbial Metabolite Trimethylamine N-Oxide is Linked to Specific Complications of Systemic Sclerosis
Albert Stec, Magdalena Maciejewska, Karolina Paralusz-Stec, Milena Michalska, Joanna Giebułtowicz, Lidia Rudnicka & Mariusz Sikora
Pages: 1895-1904
Published online: 01 May 2023
AbstractforThe Gut Microbial Metabolite Trimethylamine N-Oxide is Linked to Specific Complications of Systemic Sclerosis | Full Text | References | PDF (4.1 MB) | EPUB
  • 300 Views
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Article
TSG6 Plays a Role in Improving Orbital Inflammatory Infiltration and Extracellular Matrix Accumulation in TAO Model Mice
Xiuhui He, Siya Chen, Xiaohui Wang, Min Kong, Fangzheng Shi, Xiaoxuan Qi & Yuxin Xu
Pages: 1937-1948
Published online: 04 May 2023
AbstractforTSG6 Plays a Role in Improving Orbital Inflammatory Infiltration and Extracellular Matrix Accumulation in TAO Model Mice | Full Text | References | PDF (8.3 MB) | EPUB
  • 244 Views
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Article
Single-Cell Profiling Uncovers the Roles of Endometrial Fibrosis and Microenvironmental Changes in Adenomyosis
Weipin Niu, Yinuo Zhang, Hongyun Liu, Na Liang, Li Xu, Yalin Li, Wei Yao, Wei Shi & Zhiyong Liu
Pages: 1949-1965
Published online: 05 May 2023
AbstractforSingle-Cell Profiling Uncovers the Roles of Endometrial Fibrosis and Microenvironmental Changes in Adenomyosis | Full Text | References | PDF (13.1 MB) | EPUB
  • 327 Views
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REVIEW

Review
The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
Yan Teng, Danfeng Xu, Xianhong Yang, Hui Tang, Xiaohua Tao, Yibin Fan & Yang Ding
Pages: 1967-1977
Published online: 06 May 2023
AbstractforThe Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review | Full Text | References | PDF (2.4 MB) | EPUB
  • 380 Views
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ORIGINAL RESEARCH

Article
miR-146a-5p Promotes the Inflammatory Response in PBMCs Induced by Microcystin-Leucine-Arginine
Huiying Zhang, Daojun Chen, Qianqian Ji, Meiyan Yang & Rui Ding
Pages: 1979-1993
Published online: 09 May 2023
AbstractformiR-146a-5p Promotes the Inflammatory Response in PBMCs Induced by Microcystin-Leucine-Arginine | Full Text | References | PDF (7.3 MB) | EPUB
  • 207 Views
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Article
Nomogram Based on Hemoglobin, Albumin, Lymphocyte and Platelet Score to Predict Overall Survival in Patients with T3-4N0-1 Nasopharyngeal Carcinoma
Rong Zhao, Zhongguo Liang, Kaihua Chen & Xiaodong Zhu
Pages: 1995-2006
Published online: 09 May 2023
AbstractforNomogram Based on Hemoglobin, Albumin, Lymphocyte and Platelet Score to Predict Overall Survival in Patients with T3-4N0-1 Nasopharyngeal Carcinoma | Full Text | References | PDF (6.1 MB) | EPUB
  • 169 Views
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Article
FLI1 Regulates Histamine Decarboxylase Expression to Control Inflammation Signaling and Leukemia Progression
Jifen Hu, Jian Gao, Chunlin Wang, Wuling Liu, Anling Hu, Xiao Xiao, Yi Kuang, Kunlin Yu, Babu Gajendran, Eldad Zacksenhaus, Weidong Pan & Yaacov Ben-David
Pages: 2007-2020
Published online: 10 May 2023
AbstractforFLI1 Regulates Histamine Decarboxylase Expression to Control Inflammation Signaling and Leukemia Progression | Full Text | References | PDF (6.9 MB) | EPUB
  • 305 Views
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RESPONSE TO LETTER

Preclinical Mouse Models in Sepsis: Don’t Throw the Baby Out with the Bathwater [Response to Letter]
Wendy E Walker, Luiz F Garcia, Vishwajeet Singh, Blake Mireles & Alok Kumar Dwivedi
Pages: 2021-2022
Published online: 11 May 2023
CitationforPreclinical Mouse Models in Sepsis: Don’t Throw the Baby Out with the Bathwater [Response to Letter] | Full Text | References | PDF (298 KB) | EPUB
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ORIGINAL RESEARCH

Article
Mesenchymal Stem Cells Ameliorate DSS-Induced Experimental Colitis by Modulating the Gut Microbiota and MUC-1 Pathway
Han Wang, Yang Sun, Feng-Jun Xiao, Xia Zhao, Wei-Yuan Zhang, Yu-Jun Xia & Li-Sheng Wang
Pages: 2023-2039
Published online: 11 May 2023
AbstractforMesenchymal Stem Cells Ameliorate DSS-Induced Experimental Colitis by Modulating the Gut Microbiota and MUC-1 Pathway | Full Text | References | PDF (13 MB) | EPUB
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Article
A Diagnostic Nomogram for Early Prediction of Post-Infectious Bronchiolitis Obliterans in Severe Pneumonia
Silei Yan, Chao Sun & Kun Jiang
Pages: 2041-2050
Published online: 15 May 2023
AbstractforA Diagnostic Nomogram for Early Prediction of Post-Infectious Bronchiolitis Obliterans in Severe Pneumonia | Full Text | References | PDF (3.4 MB) | EPUB
  • 223 Views
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Article
Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio are Important Indicators for Predicting in-Hospital Death in Elderly AMI Patients
Yan Chen, Shengyue Chen, Yuanyuan Han, Qing Xu & Xin Zhao
Pages: 2051-2061
Published online: 15 May 2023
AbstractforNeutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio are Important Indicators for Predicting in-Hospital Death in Elderly AMI Patients | Full Text | References | PDF (3 MB) | EPUB
  • 236 Views
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Article
Risk Prediction Model for Necrotizing Pneumonia in Children with Mycoplasma pneumoniae Pneumonia
Yonghan Luo & Yanchun Wang
Pages: 2079-2087
Published online: 15 May 2023
AbstractforRisk Prediction Model for Necrotizing Pneumonia in Children with Mycoplasma pneumoniae Pneumonia | Full Text | References | PDF (3.3 MB) | EPUB
  • 341 Views
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Article
Prediction and Verification of Potential Therapeutic Targets for Non-Responders to Infliximab in Ulcerative Colitis
Xue Lyu, Zhe Zhang, Xia Liu, Li Geng, Muhan Zhang & Baisui Feng
Pages: 2063-2078
Published online: 15 May 2023
AbstractforPrediction and Verification of Potential Therapeutic Targets for Non-Responders to Infliximab in Ulcerative Colitis | Full Text | References | PDF (10.8 MB) | EPUB
  • 195 Views
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REVIEW

Review
Stem Cell Therapy in Inflammatory Bowel Disease: A Review of Achievements and Challenges
Cheng-Mei Tian, Yuan Zhang, Mei-Feng Yang, Hao-Ming Xu, Min-Zheng Zhu, Jun Yao, Li-Sheng Wang, Yu-Jie Liang & De-Feng Li
Pages: 2089-2119
Published online: 16 May 2023
AbstractforStem Cell Therapy in Inflammatory Bowel Disease: A Review of Achievements and Challenges | Full Text | References | PDF (5 MB) | EPUB
  • 864 Views
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Review
Sparcl1 and Atherosclerosis
Xu Cheng, Xinyan Chen, Min Zhang, Yufeng Wan, Shenglin Ge & Xiaowen Cheng
Pages: 2121-2127
Published online: 17 May 2023
AbstractforSparcl1 and Atherosclerosis | Full Text | References | PDF (905.4 KB) | EPUB
  • 190 Views
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Review
Research Progress of Hydrogen on Chronic Nasal Inflammation
Ling Jin, Shiwang Tan, Kai Fan, Yang Wang & Shaoqing Yu
Pages: 2149-2157
Published online: 17 May 2023
AbstractforResearch Progress of Hydrogen on Chronic Nasal Inflammation | Full Text | References | PDF (2.4 MB) | EPUB
  • 254 Views
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ORIGINAL RESEARCH

Article
Transcriptional Characterization of Bronchoalveolar Lavage Fluid Reveals Immune Microenvironment Alterations in Chemically Induced Acute Lung Injury
Chao Cao, Obulkasim Memet, Fuli Liu, Hanbing Hu, Lin Zhang, Heng Jin, Yiqun Cao, Jian Zhou & Jie Shen
Pages: 2129-2147
Published online: 17 May 2023
AbstractforTranscriptional Characterization of Bronchoalveolar Lavage Fluid Reveals Immune Microenvironment Alterations in Chemically Induced Acute Lung Injury | Full Text | References | PDF (17 MB) | EPUB
  • 187 Views
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REVIEW

Review
Antigen Recognition and Immune Response to Acute and Chronic Hepatitis B Virus Infection
Adane Adugna
Pages: 2159-2166
Published online: 18 May 2023
AbstractforAntigen Recognition and Immune Response to Acute and Chronic Hepatitis B Virus Infection | Full Text | References | PDF (972.9 KB) | EPUB
  • 345 Views
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Open Access

CASE REPORT

Case Report
Tofacitinib for the Treatment of Psoriasiform Dermatitis Caused by IL-17 Inhibitors: A Case Report
Nan Luo, Lingyuan Zhong, Nana Luo, Qiuyue Wang, Tianhao Li & Pingsheng Hao
Pages: 2167-2172
Published online: 19 May 2023
AbstractforTofacitinib for the Treatment of Psoriasiform Dermatitis Caused by IL-17 Inhibitors: A Case Report | Full Text | References | PDF (3.1 MB) | EPUB
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ORIGINAL RESEARCH

Article
Significance of Immunogenic Cell Death-Related Prognostic Gene Signature in Cervical Cancer Prognosis and Anti-Tumor Immunity
Shan Jiang, Zhaolei Cui, Jianfeng Zheng, Qiaoling Wu, Haijuan Yu, Yiqing You, Chaoqiang Zheng & Yang Sun
Pages: 2189-2207
Published online: 22 May 2023
AbstractforSignificance of Immunogenic Cell Death-Related Prognostic Gene Signature in Cervical Cancer Prognosis and Anti-Tumor Immunity | Full Text | References | PDF (21.8 MB) | EPUB
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Article
The Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality
Blanka Wolszczak-Biedrzycka, Justyna Dorf, Anna Milewska, Mateusz Łukaszyk, Wojciech Naumnik, Jakub Wiktor Kosidło & Violetta Dymicka-Piekarska
Pages: 2173-2188
Published online: 22 May 2023
AbstractforThe Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality | Full Text | References | PDF (3.7 MB) | EPUB
  • 276 Views
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Article
Neutrophil/Lymphocyte Ratio (NLR) and Lymphocyte/Monocyte Ratio (LMR) – Risk of Death Inflammatory Biomarkers in Patients with COVID-19
Violetta Dymicka-Piekarska, Justyna Dorf, Anna Milewska, Mateusz Łukaszyk, Jakub Wiktor Kosidło, Joanna Kamińska, Blanka Wolszczak-Biedrzycka & Wojciech Naumnik
Pages: 2209-2222
Published online: 23 May 2023
AbstractforNeutrophil/Lymphocyte Ratio (NLR) and Lymphocyte/Monocyte Ratio (LMR) – Risk of Death Inflammatory Biomarkers in Patients with COVID-19 | Full Text | References | PDF (2.9 MB) | EPUB
  • 315 Views
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Article
Therapeutic Effect of Acupotomy at Sanheyang for Cartilage Collagen Damage in Moderate Knee Osteoarthritis: A Rabbit Model
Yuanyuan Li, Yimin Hou, Jiwei Sun, Jiabi Wei, Yemao Chai, Mengwei Guo & Rongguo Wang
Pages: 2241-2254
Published online: 24 May 2023
AbstractforTherapeutic Effect of Acupotomy at Sanheyang for Cartilage Collagen Damage in Moderate Knee Osteoarthritis: A Rabbit Model | Full Text | References | PDF (7.9 MB) | EPUB
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Article
The Molecular Mechanisms Study of Engeletin Suppresses RANKL-Induced Osteoclastogenesis and Inhibits Ovariectomized Murine Model Bone Loss
Mingzhe Feng, Lin Liu, Jiang Wang, Jialang Zhang, Zechao Qu, Yanjun Wang & Baorong He
Pages: 2255-2270
Published online: 24 May 2023
AbstractforThe Molecular Mechanisms Study of Engeletin Suppresses RANKL-Induced Osteoclastogenesis and Inhibits Ovariectomized Murine Model Bone Loss | Full Text | References | PDF (10 MB) | EPUB
  • 207 Views
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REVIEW

Review
Insights into the Role of Inflammation in the Management of Atherosclerosis
Viviane Zorzanelli Rocha, Fabiana Hanna Rached & Marcio Hiroshi Miname
Pages: 2223-2239
Published online: 24 May 2023
AbstractforInsights into the Role of Inflammation in the Management of Atherosclerosis | Full Text | References | PDF (1 MB) | EPUB
  • 508 Views
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ORIGINAL RESEARCH

Article
Magnoflorine Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response via the NF-κB/MAPK Signaling Pathways
Lei Wang, Pengfei Li, Yu Zhou, Renjun Gu, Ge Lu & Chunbing Zhang
Pages: 2271-2296
Published online: 27 May 2023
AbstractforMagnoflorine Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response via the NF-κB/MAPK Signaling Pathways | Full Text | References | PDF (21 MB) | EPUB
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Article
Multi-Omics Analysis and Verification of the Oncogenic Value of CCT8 in Pan-Cancers
Lian Gong, Ming Zhong, Kai Gong, Zhanwang Wang, Yong Zhong, Yi Jin, Haotian Chen, Panpan Tai, Xinyu Chen, Aiyan Chen & Ke Cao
Pages: 2297-2315
Published online: 29 May 2023
AbstractforMulti-Omics Analysis and Verification of the Oncogenic Value of CCT8 in Pan-Cancers | Full Text | References | PDF (18 MB) | EPUB
  • 241 Views
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Article
Relationship Between the Expression of LC3 (Microtubule-Associated Protein 1A/1B-Light Chain 3) in Nasal Mucosa and Serum IL-5 and IL-4 Concentrations in Allergic Rhinitis Mice
Hui Pi, Ming-Fang Xu & Hai-Tao Lu
Pages: 2317-2328
Published online: 29 May 2023
AbstractforRelationship Between the Expression of LC3 (Microtubule-Associated Protein 1A/1B-Light Chain 3) in Nasal Mucosa and Serum IL-5 and IL-4 Concentrations in Allergic Rhinitis Mice | Full Text | References | PDF (6.5 MB) | EPUB
  • 180 Views
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REVIEW

Review
Effects of Immune Cells and Cytokines on Different Cells in OA
Pan Luo, Qiling Yuan, Xianjie Wan, Mingyi Yang & Peng Xu
Pages: 2329-2343
Published online: 30 May 2023
AbstractforEffects of Immune Cells and Cytokines on Different Cells in OA | Full Text | References | PDF (1.5 MB) | EPUB
  • 249 Views
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ORIGINAL RESEARCH

Article
Effects of Cooling Interventions with Different Target Temperatures on Heat Stroke Rats
Changdong Wu, Ping Wang, Bin Wang, Muyesai Nijiati & Ming Hou
Pages: 2345-2355
Published online: 31 May 2023
AbstractforEffects of Cooling Interventions with Different Target Temperatures on Heat Stroke Rats | Full Text | References | PDF (12.5 MB) | EPUB
  • 144 Views
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Article
Systematic and Comprehensive Analysis of tRNA-Derived Small RNAs Reveals Their Potential Regulatory Roles and Clinical Relevance in Sarcoidosis
Min Zhao, Chang Tian, Xin Di, Shan Cong, Yingshu Cao, Xijia Zhou & Ke Wang
Pages: 2357-2374
Published online: 01 Jun 2023
AbstractforSystematic and Comprehensive Analysis of tRNA-Derived Small RNAs Reveals Their Potential Regulatory Roles and Clinical Relevance in Sarcoidosis | Full Text | References | PDF (8.1 MB) | EPUB
  • 205 Views
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Article
Predictive Value of the Changes in Neutrophil-Lymphocyte Ratio for Outcomes After Off-Pump Coronary Surgery
Myung Il Bae, Jae-Kwang Shim, Jong Wook Song, Seo Hee Ko, Young Seo Choi & Young-Lan Kwak
Pages: 2375-2385
Published online: 02 Jun 2023
AbstractforPredictive Value of the Changes in Neutrophil-Lymphocyte Ratio for Outcomes After Off-Pump Coronary Surgery | Full Text | References | PDF (2.1 MB) | EPUB
  • 215 Views
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Article
Analysis of lncRNA-miRNA-mRNA Expression in the Troxerutin-Mediated Prevention of Radiation-Induced Lung Injury in Mice
Nan Zhang, Gui-yuan Song, Yong-jian Hu, Xia Wang, Tian-zhu Chao, Yao-yao Wu & Ping Xu
Pages: 2387-2399
Published online: 03 Jun 2023
AbstractforAnalysis of lncRNA-miRNA-mRNA Expression in the Troxerutin-Mediated Prevention of Radiation-Induced Lung Injury in Mice | Full Text | References | PDF (10.3 MB) | EPUB
  • 179 Views
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Article
The Correlation Between Aldosterone and Leukocyte-Related Inflammation: A Comparison Between Patients with Primary Aldosteronism and Essential Hypertension
Kun-Rui Rao, Ru-Yi Bao, Hu Ming, Jian-Wei Liu & Yi-Fei Dong
Pages: 2401-2413
Published online: 05 Jun 2023
AbstractforThe Correlation Between Aldosterone and Leukocyte-Related Inflammation: A Comparison Between Patients with Primary Aldosteronism and Essential Hypertension | Full Text | References | PDF (2.9 MB) | EPUB
  • 156 Views
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Article
Albumin Corrected Anion Gap and the Risk of in-Hospital Mortality in Patients with Acute Pancreatitis: A Retrospective Cohort Study
Ping Li, Lvyuan Shi, Xin Yan, Lietao Wang, Dingyuan Wan, Zhongwei Zhang & Min He
Pages: 2415-2422
Published online: 07 Jun 2023
AbstractforAlbumin Corrected Anion Gap and the Risk of in-Hospital Mortality in Patients with Acute Pancreatitis: A Retrospective Cohort Study | Full Text | References | PDF (1.6 MB) | EPUB
  • 208 Views
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Article
Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) Can Predict Spontaneous Preterm Birth?
Ebru Yuce
Pages: 2423-2429
Published online: 08 Jun 2023
AbstractforNeutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) Can Predict Spontaneous Preterm Birth? | Full Text | References | PDF (504.1 KB) | EPUB
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Article
LncRNA THRIL Functions as a Marker for Carotid Artery Stenosis and Affects the Biological Function of Human Aortic Endothelial Cell
Fei Wang, Ying Wang & Xichun Guo
Pages: 2437-2446
Published online: 08 Jun 2023
AbstractforLncRNA THRIL Functions as a Marker for Carotid Artery Stenosis and Affects the Biological Function of Human Aortic Endothelial Cell | Full Text | References | PDF (5.2 MB) | EPUB
  • 152 Views
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Open Access

SHORT REPORT

Brief Report
The Technical Feasibility of Digital Spatial Profiling in Immune/Inflammation Study of Thrombosis
Jianjun Jiang & Yang Liu
Pages: 2431-2436
Published online: 08 Jun 2023
AbstractforThe Technical Feasibility of Digital Spatial Profiling in Immune/Inflammation Study of Thrombosis | Full Text | References | PDF (2.3 MB) | EPUB
  • 458 Views
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RETRACTION

Retraction
Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling [Retraction]
Pages: 2447-2448
Published online: 09 Jun 2023
CitationforGinsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling [Retraction] | Full Text | PDF (240.3 KB) | EPUB
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ORIGINAL RESEARCH

Article
Nomogram Based on Inflammatory Factor to Predict Therapeutic Response of Thrombocytopenia in Patients with Primary Sjögren’s Syndrome
Minzhi Gan, Yong Peng, Mengya Zhu & Ying Ying
Pages: 2449-2459
Published online: 12 Jun 2023
AbstractforNomogram Based on Inflammatory Factor to Predict Therapeutic Response of Thrombocytopenia in Patients with Primary Sjögren’s Syndrome | Full Text | References | PDF (3.6 MB) | EPUB
  • 185 Views
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REVIEW

Review
Non-Coding RNAs Regulate Spinal Cord Injury-Related Neuropathic Pain via Neuroinflammation
Jing Zhu, Fei Huang, Yonglin Hu, Wei Qiao, Yingchao Guan, Zhi-Jun Zhang, Su Liu & Ying Liu
Pages: 2477-2489
Published online: 13 Jun 2023
AbstractforNon-Coding RNAs Regulate Spinal Cord Injury-Related Neuropathic Pain via Neuroinflammation | Full Text | References | PDF (3.3 MB) | EPUB
  • 218 Views
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ORIGINAL RESEARCH

Article
Identification of Novel Targets for Treatment of Dilated Cardiomyopathy Based on the Ferroptosis and Immune Heterogeneity
Hongyu Lu, Yun Xie, Ziyou Zhou, Peijian Hong & Jiyan Chen
Pages: 2461-2476
Published online: 13 Jun 2023
AbstractforIdentification of Novel Targets for Treatment of Dilated Cardiomyopathy Based on the Ferroptosis and Immune Heterogeneity | Full Text | References | PDF (12.1 MB) | EPUB
  • 217 Views
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Article
Neutrophil-Related Gene Expression Signatures in Idiopathic Pulmonary Fibrosis: Implications for Disease Characteristic and Identification of Diagnostic Hub Genes
Yingying Lin, Xiaofan Lai, Tianxiang Lei, Yuan Qiu, Qiwen Deng, Qi Liu, Zhongxing Wang & Wenqi Huang
Pages: 2503-2519
Published online: 14 Jun 2023
AbstractforNeutrophil-Related Gene Expression Signatures in Idiopathic Pulmonary Fibrosis: Implications for Disease Characteristic and Identification of Diagnostic Hub Genes | Full Text | References | PDF (12.9 MB) | EPUB
  • 205 Views
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REVIEW

Review
TLR5 Signaling in the Regulation of Intestinal Mucosal Immunity
Shuyan Feng, Chi Zhang, Shanshan Chen, Ruonan He, Guanqun Chao & Shuo Zhang
Pages: 2491-2501
Published online: 14 Jun 2023
AbstractforTLR5 Signaling in the Regulation of Intestinal Mucosal Immunity | Full Text | References | PDF (3.6 MB) | EPUB
  • 357 Views
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ORIGINAL RESEARCH

Article
Psoriasis and Leprosy: An Arcane Relationship
Gai Ge, Jingzhe Shang, Tian Gan, Zhiming Chen, Chun Pan, Youming Mei, Siyu Long, Aiping Wu & Hongsheng Wang
Pages: 2521-2533
Published online: 14 Jun 2023
AbstractforPsoriasis and Leprosy: An Arcane Relationship | Full Text | References | PDF (7.2 MB) | EPUB
  • 257 Views
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Article
Omarigliptin Protects the Integrity of the Blood–Brain Barrier After Intracerebral Hemorrhage in Mice
Yan Zhang, Yang Liu, Xiangyu Zhang, V Wee Yong & Mengzhou Xue
Pages: 2535-2548
Published online: 15 Jun 2023
AbstractforOmarigliptin Protects the Integrity of the Blood–Brain Barrier After Intracerebral Hemorrhage in Mice | Full Text | References | PDF (10.2 MB) | EPUB
  • 248 Views
  • 3 CrossRef citations
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Article
Clinical Utility of the Neutrophil-to-Bilirubin Ratio in the Detection of Disease Activity in Ulcerative Colitis
Xijing Huang, Yan Pan, Ya Liu, Zhou Zhou, Yinghui Zhang, Caiping Gao & Chong He
Pages: 2549-2559
Published online: 16 Jun 2023
AbstractforClinical Utility of the Neutrophil-to-Bilirubin Ratio in the Detection of Disease Activity in Ulcerative Colitis | Full Text | References | PDF (4.3 MB) | EPUB
  • 149 Views
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Article
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation
Wanyue Sang, Lu Wang, Xiaoji Yan, Huaxin Sun, Yafan Han, Feifei Wang, Baopeng Tang & Yaodong Li
Pages: 2561-2583
Published online: 16 Jun 2023
AbstractforEstablishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation | Full Text | References | PDF (10.9 MB) | EPUB
  • 230 Views
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Article
Regulatory Effect and Mechanism of Erythroblastic Island Macrophages on Anemia in Patients with Newly Diagnosed Multiple Myeloma
Hao Huang, Peng-Yang Yu, Chen Wei, Yang-Wei Li, Li-Jie Liang, Yu-Zhang Liu, Li-Na Liu, Bai-Jun Fang & Yao-Mei Wang
Pages: 2585-2594
Published online: 17 Jun 2023
AbstractforRegulatory Effect and Mechanism of Erythroblastic Island Macrophages on Anemia in Patients with Newly Diagnosed Multiple Myeloma | Full Text | References | PDF (3.2 MB) | EPUB
  • 192 Views
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Article
Ciliated Cells Express a Novel Pattern of Brain-Derived Neurotrophic Factor in Allergic Rhinitis
Li Fang, Chun-Hao Li, Qian Zhang, Tian-Jiao Jiang, Yuan Liu, Feng-Po Shi, Peng Yu, Liang Yu, Ai-Ping Chen, Tao Li, Yu-Zhu Wan & Li Shi
Pages: 2595-2606
Published online: 19 Jun 2023
AbstractforCiliated Cells Express a Novel Pattern of Brain-Derived Neurotrophic Factor in Allergic Rhinitis | Full Text | References | PDF (6 MB) | EPUB
  • 176 Views
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Article
HSP90-Dependent Upregulation of EZH2 Promotes Hypoxia/Reoxygenation-Induced Pyroptosis by Inhibiting miR-22 in Endothelial Cells
Paihe Deng & Huimin Hu
Pages: 2615-2630
Published online: 19 Jun 2023
AbstractforHSP90-Dependent Upregulation of EZH2 Promotes Hypoxia/Reoxygenation-Induced Pyroptosis by Inhibiting miR-22 in Endothelial Cells | Full Text | References | PDF (11.1 MB) | EPUB
  • 176 Views
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Article
The Flow Cytometric Analysis of Peripheral Blood Lymphocytes and Expression of HLA II Molecules in Lymphocyte During Acute Rejection After Renal Transplantation
Jianzhuang Guo, Chengwei Qin, Xiangdong Li & Xiaoxuan Zhuang
Pages: 2607-2613
Published online: 19 Jun 2023
AbstractforThe Flow Cytometric Analysis of Peripheral Blood Lymphocytes and Expression of HLA II Molecules in Lymphocyte During Acute Rejection After Renal Transplantation | Full Text | References | PDF (1.1 MB) | EPUB
  • 153 Views
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Article
Early Cytokine Signatures of Hospitalized Mild and Severe COVID-19 Patients: A Prospective Observational Study
Assim A Alfadda, Khalid Siddiqui, Mohamed Rafiullah, Mohammad AlKhowaiter, Naif Alotaibi, Musa Alzahrani, Khalifa Binkhamis, Amira M Youssef, Haifa Altalhi, Ibrahim Almaghlouth, Mohammed Alarifi, Saleh Albanyan, Mohammed F Alosaimi, Arthur Isnani, Shaik S Nawaz & Khalid Alayed
Pages: 2631-2643
Published online: 22 Jun 2023
AbstractforEarly Cytokine Signatures of Hospitalized Mild and Severe COVID-19 Patients: A Prospective Observational Study | Full Text | References | PDF (2.3 MB) | EPUB
  • 274 Views
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REVIEW

Review
Progress in the Treatment of High Altitude Cerebral Edema: Targeting REDOX Homeostasis
Yubo Li, Chengming Li, Tao Luo, Tian Yue, Wenjing Xiao, Ling Yang, Zaiyuan Zhang, Fei Han, Pan Long & Yonghe Hu
Pages: 2645-2660
Published online: 23 Jun 2023
AbstractforProgress in the Treatment of High Altitude Cerebral Edema: Targeting REDOX Homeostasis | Full Text | References | PDF (4.5 MB) | EPUB
  • 261 Views
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Review
The Emerging Roles of Ferroptosis in Neonatal Diseases
Wenqian Chen, Dali Zheng & Changyi Yang
Pages: 2661-2674
Published online: 26 Jun 2023
AbstractforThe Emerging Roles of Ferroptosis in Neonatal Diseases | Full Text | References | PDF (2.3 MB) | EPUB
  • 238 Views
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Review
Future Biomarkers for Infection and Inflammation in Rheumatoid Arthritis
Shuang Cui & Jie Qian
Pages: 2719-2726
Published online: 29 Jun 2023
AbstractforFuture Biomarkers for Infection and Inflammation in Rheumatoid Arthritis | Full Text | References | PDF (427.5 KB) | EPUB
  • 310 Views
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ORIGINAL RESEARCH

Article
Puerarin Attenuates High-Glucose and High-Lipid-Induced Inflammatory Injury in H9c2 Cardiomyocytes via CAV3 Protein Upregulation
YiFu Tian, CaiXia Zhou, XiaoYang Bu, Qian Lv & Qin Huang
Pages: 2707-2718
Published online: 29 Jun 2023
AbstractforPuerarin Attenuates High-Glucose and High-Lipid-Induced Inflammatory Injury in H9c2 Cardiomyocytes via CAV3 Protein Upregulation | Full Text | References | PDF (6.4 MB) | EPUB
  • 189 Views
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Article
NEAT1/microRNA 339-5p/SPI1 Axis Feedback Loop Contributes to Osteogenic Differentiation in Acute Suppurative Osteomyelitis in Children
Dongsheng Zhu, Zhitao Zhu & Han Qi
Pages: 2675-2687
Published online: 29 Jun 2023
AbstractforNEAT1/microRNA 339-5p/SPI1 Axis Feedback Loop Contributes to Osteogenic Differentiation in Acute Suppurative Osteomyelitis in Children | Full Text | References | PDF (8.8 MB) | EPUB
  • 162 Views
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Article
Expression and Significance of KIM-1, NGAL, and HO-1 in Patients with Acute Kidney Injury After Cardiac Valve Replacement
Bin Zhang, Yanyan Song, Qian Ma, Jian Yang & Lei Bai
Pages: 2755-2761
Published online: 30 Jun 2023
AbstractforExpression and Significance of KIM-1, NGAL, and HO-1 in Patients with Acute Kidney Injury After Cardiac Valve Replacement | Full Text | References | PDF (442.9 KB) | EPUB
  • 204 Views
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Article
Identification of Shared Immune Cells and Immune-Related Co-Disease Genes in Chronic Heart Failure and Systemic Lupus Erythematosus Based on Transcriptome Sequencing
Ziyue Luo, Guifang Lu, Qiang Yang, Juncan Ding, Tianyu Wang & Pengfei Hu
Pages: 2689-2705
Published online: 30 Jun 2023
AbstractforIdentification of Shared Immune Cells and Immune-Related Co-Disease Genes in Chronic Heart Failure and Systemic Lupus Erythematosus Based on Transcriptome Sequencing | Full Text | References | PDF (14 MB) | EPUB
  • 193 Views
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REVIEW

Review
Programmed Cell Death in Asthma: Apoptosis, Autophagy, Pyroptosis, Ferroptosis, and Necroptosis
Lu Liu, Ling Zhou, Ling-Ling Wang, Peng-Dou Zheng, Feng-Qin Zhang, Zhen-Yu Mao, Huo-Jun Zhang & Hui-Guo Liu
Pages: 2727-2754
Published online: 01 Jul 2023
AbstractforProgrammed Cell Death in Asthma: Apoptosis, Autophagy, Pyroptosis, Ferroptosis, and Necroptosis | Full Text | References | PDF (5.3 MB) | EPUB
  • 609 Views
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CASE SERIES

Case Report
Transient Increase in Patient Numbers with “Acute Macular Neuroretinopathy” Post SARS-CoV-2 Infection—Case Series During the First Surge of Infection in December 2022
Bing Xu, Jie Zhang, Ying Zhang, Yang Cheng & Qiong Huang
Pages: 2763-2771
Published online: 03 Jul 2023
AbstractforTransient Increase in Patient Numbers with “Acute Macular Neuroretinopathy” Post SARS-CoV-2 Infection—Case Series During the First Surge of Infection in December 2022 | Full Text | References | PDF (2.8 MB) | EPUB
  • 403 Views
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ORIGINAL RESEARCH

Article
Endothelial-Related Biomarkers in Evaluation of Vascular Function During Progression of Sepsis After Severe Trauma: New Potential Diagnostic Tools in Sepsis
Biao Yang, Xiaoyong Wang, Zhaorui Liu, Zhengmao Lu, Guoen Fang, Xuchao Xue & Tianhang Luo
Pages: 2773-2782
Published online: 06 Jul 2023
AbstractforEndothelial-Related Biomarkers in Evaluation of Vascular Function During Progression of Sepsis After Severe Trauma: New Potential Diagnostic Tools in Sepsis | Full Text | References | PDF (1.5 MB) | EPUB
  • 193 Views
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REVIEW

Review
Distinct Features of Vascular Diseases in COVID-19
Alexandr Ceasovschih, Victorita Sorodoc, Annabelle Shor, Raluca Ecaterina Haliga, Lynn Roth, Catalina Lionte, Viviana Onofrei Aursulesei, Oana Sirbu, Nicolae Culis, Albina Shapieva, Mohammed AR Tahir Khokhar, Cristian Statescu, Radu A Sascau, Adorata Elena Coman, Alexandra Stoica, Elena-Daniela Grigorescu, Maciej Banach, Costas Thomopoulos & Laurentiu Sorodoc
Pages: 2783-2800
Published online: 06 Jul 2023
AbstractforDistinct Features of Vascular Diseases in COVID-19 | Full Text | References | PDF (2.6 MB) | EPUB
  • 388 Views
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Review
Efferocytosis: An Emerging Therapeutic Strategy for Type 2 Diabetes Mellitus and Diabetes Complications
Xun Liu, Hua Liu & Yihui Deng
Pages: 2801-2815
Published online: 07 Jul 2023
AbstractforEfferocytosis: An Emerging Therapeutic Strategy for Type 2 Diabetes Mellitus and Diabetes Complications | Full Text | References | PDF (3.4 MB) | EPUB
  • 356 Views
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Review
Research Progress of Cordyceps sinensis and Its Fermented Mycelium Products on Ameliorating Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition
Yaling Zhang, Kaiyun Li, Chao Zhang, Hui Liao & Rongshan Li
Pages: 2817-2830
Published online: 07 Jul 2023
AbstractforResearch Progress of Cordyceps sinensis and Its Fermented Mycelium Products on Ameliorating Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition | Full Text | References | PDF (3.1 MB) | EPUB
  • 328 Views
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ORIGINAL RESEARCH

Article
Establishment and Validation of a Nomogram Prediction Model for the Severe Acute Pancreatitis
Bo Li, Weiqing Wu, Aijun Liu, Lifeng Feng, Bin Li, Yong Mei, Li Tan, Chaoyang Zhang & Yangtao Tian
Pages: 2831-2843
Published online: 08 Jul 2023
AbstractforEstablishment and Validation of a Nomogram Prediction Model for the Severe Acute Pancreatitis | Full Text | References | PDF (5.5 MB) | EPUB
  • 178 Views
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Article
Predictive Value of Systemic Inflammation Score for Contrast-Associated Acute Kidney Injury and Adverse Outcomes Among Patients Undergoing Elective Percutaneous Coronary Intervention
Ji-Lang Zeng, Yi-Fei Xiang, Li-Wei Zhang, Li-Chuan Chen, Jun-Han Chen, Wen-Jia Liang, Zhebin You, Chang-Xi Wang, Zhi-Jie Lin, Kai-Yang Lin & Yansong Guo
Pages: 2845-2854
Published online: 08 Jul 2023
AbstractforPredictive Value of Systemic Inflammation Score for Contrast-Associated Acute Kidney Injury and Adverse Outcomes Among Patients Undergoing Elective Percutaneous Coronary Intervention | Full Text | References | PDF (1.6 MB) | EPUB
  • 220 Views
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Article
High-Dose Vitamin C Alleviates Pancreatic Necrosis by Inhibiting Platelet Activation Through the CXCL12/CXCR4 Pathway in Severe Acute Pancreatitis
Menglu Gui, Jun Huang, Huiqiu Sheng, Ying Chen, Zhitao Yang, Li Ma, Daosheng Wang, Lili Xu, Wenwu Sun, Junling Liu, Yanyan Xu, Erzhen Chen, Bing Zhao & Enqiang Mao
Pages: 2865-2877
Published online: 10 Jul 2023
AbstractforHigh-Dose Vitamin C Alleviates Pancreatic Necrosis by Inhibiting Platelet Activation Through the CXCL12/CXCR4 Pathway in Severe Acute Pancreatitis | Full Text | References | PDF (5.9 MB) | EPUB
  • 212 Views
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Article
Altered Phenotypes of Colonic and Peripheral Blood Follicular Helper and Follicular Cytotoxic T Cells in Mice with DSS-Induced Colitis
Yan Long, Chang-Sheng Xia, Xingyue Zeng, Jinghong Feng, Yinting Ma & Chen Liu
Pages: 2879-2892
Published online: 10 Jul 2023
AbstractforAltered Phenotypes of Colonic and Peripheral Blood Follicular Helper and Follicular Cytotoxic T Cells in Mice with DSS-Induced Colitis | Full Text | References | PDF (8.9 MB) | EPUB
  • 335 Views
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Article
Identifying Immune Cell Infiltration and Hub Genes During the Myocardial Remodeling Process After Myocardial Infarction
Yuan Tian, Zilin Wang, Feng Liang & Yi Wang
Pages: 2893-2906
Published online: 11 Jul 2023
AbstractforIdentifying Immune Cell Infiltration and Hub Genes During the Myocardial Remodeling Process After Myocardial Infarction | Full Text | References | PDF (4.4 MB) | EPUB
  • 206 Views
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Article
Pan-Cancer Analysis Reveals CENPI as a Potential Biomarker and Therapeutic Target in Adrenocortical Carcinoma
Feima Wu, Guangchao Li, Huijuan Shen, Jing Huang, Zhi Liu, Yangmin Zhu, Qi Zhong, Ruiming Ou, Qing Zhang & Shuang Liu
Pages: 2907-2928
Published online: 12 Jul 2023
AbstractforPan-Cancer Analysis Reveals CENPI as a Potential Biomarker and Therapeutic Target in Adrenocortical Carcinoma | Full Text | References | PDF (24.7 MB) | EPUB
  • 287 Views
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Article
A Novel Hematological Inflammation-Nutrition Score (HINS) and Its Related Nomogram Model to Predict Survival Outcome in Advanced Gastric Cancer Patients Receiving First-Line Palliative Chemotherapy
Chen Chen, Zehua Wang & Yanru Qin
Pages: 2929-2946
Published online: 12 Jul 2023
AbstractforA Novel Hematological Inflammation-Nutrition Score (HINS) and Its Related Nomogram Model to Predict Survival Outcome in Advanced Gastric Cancer Patients Receiving First-Line Palliative Chemotherapy | Full Text | References | PDF (9.3 MB) | EPUB
  • 183 Views
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Article
Predictive Value of PRISMA-7, qSOFA, ESI, and CFS for 28-Day Mortality in Elderly Patients in the Emergency Department
Liqun Hao, Yue Zhou, Jiatong Zou, Lirong Hao & Peng Deng
Pages: 2947-2954
Published online: 13 Jul 2023
AbstractforPredictive Value of PRISMA-7, qSOFA, ESI, and CFS for 28-Day Mortality in Elderly Patients in the Emergency Department | Full Text | References | PDF (2.1 MB) | EPUB
  • 160 Views
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Article
Development and Validation of a Rapid and Efficient Prognostic Scoring System for Sepsis Based on Oxygenation Index, Lactate and Glasgow Coma Scale
Qiang Lai, Yiqin Xia, Wentao Yang & Yiwu Zhou
Pages: 2955-2966
Published online: 18 Jul 2023
AbstractforDevelopment and Validation of a Rapid and Efficient Prognostic Scoring System for Sepsis Based on Oxygenation Index, Lactate and Glasgow Coma Scale | Full Text | References | PDF (4.1 MB) | EPUB
  • 179 Views
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Article
Clinical Features and Predictive Nomogram of Acute Kidney Injury in Aging Population Infected with SARS-CoV-2 Omicron Variant
Yumei Zhang, Xin Li, Suning Zhang, Wei Chen, Jianxin Lu, Yingxin Xie, Shengbin Wu, Feng Zhuang, Xiao Bi, Mingzi Chu, Feng Wang, Yemin Huang, Feng Ding, Chun Hu & Yu Pan
Pages: 2967-2978
Published online: 18 Jul 2023
AbstractforClinical Features and Predictive Nomogram of Acute Kidney Injury in Aging Population Infected with SARS-CoV-2 Omicron Variant | Full Text | References | PDF (4.2 MB) | EPUB
  • 172 Views
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Article
The Role of Albumin in the Diagnosis of Neonatal Sepsis Over the Last 11 Years: A Retrospective Study
Jipeng Shi, Zhen-Qi Lu, Qing-Mei Lin, Wang Zeng, Ping-Jiao Gu, Qing Yu, Jing Long, Da-Gui Huang & Yi-Heng Dai
Pages: 2855-2863
Published online: 19 Jul 2023
AbstractforThe Role of Albumin in the Diagnosis of Neonatal Sepsis Over the Last 11 Years: A Retrospective Study | Full Text | References | PDF (1.4 MB) | EPUB
  • 228 Views
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Article
Impact of Early Natural Killer Cell Reconstitution on the Outcomes of T Cell-Replete Allogeneic Hematopoietic Stem Cell Transplantation
Ziwei Zhou, Xuan Liu, Xuejun Zhang, Shupeng Wen, Huan Hua, Zhenzhen Wang, Zheng Xu, Yu Lu & Fuxu Wang
Pages: 2993-3008
Published online: 19 Jul 2023
AbstractforImpact of Early Natural Killer Cell Reconstitution on the Outcomes of T Cell-Replete Allogeneic Hematopoietic Stem Cell Transplantation | Full Text | References | PDF (7.4 MB) | EPUB
  • 202 Views
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REVIEW

Review
Complex Neuroimmune Involvement in Neurodevelopment: A Mini-Review
Marianne C Monet & Ning Quan
Pages: 2979-2991
Published online: 19 Jul 2023
AbstractforComplex Neuroimmune Involvement in Neurodevelopment: A Mini-Review | Full Text | References | PDF (1.5 MB) | EPUB
  • 285 Views
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ORIGINAL RESEARCH

Article
Association Between Inflammatory Burden Index and Unfavorable Prognosis After Endovascular Thrombectomy in Acute Ischemic Stroke
Mingyang Du, Lili Xu, Xiaohao Zhang, Xianjun Huang, Hui Cao, Feng Qiu, Wenya Lan & Haibo Jiang
Pages: 3009-3017
Published online: 19 Jul 2023
AbstractforAssociation Between Inflammatory Burden Index and Unfavorable Prognosis After Endovascular Thrombectomy in Acute Ischemic Stroke | Full Text | References | PDF (2.3 MB) | EPUB
  • 172 Views
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Article
M1-Type Macrophages Secrete TNF-α to Stimulate Vascular Calcification by Upregulating CA1 and CA2 Expression in VSMCs
Xianqin Song, Yu Song, Quanping Ma, Kehua Fang & Xiaotian Chang
Pages: 3019-3032
Published online: 19 Jul 2023
AbstractforM1-Type Macrophages Secrete TNF-α to Stimulate Vascular Calcification by Upregulating CA1 and CA2 Expression in VSMCs | Full Text | References | PDF (9 MB) | EPUB
  • 181 Views
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Article
Application of Circulating Tumor Cells and Interleukin-6 in Preoperative Prediction of Peritoneal Metastasis of Advanced Gastric Cancer
Zitao Liu, Huakai Tian & Zhengming Zhu
Pages: 3033-3047
Published online: 20 Jul 2023
AbstractforApplication of Circulating Tumor Cells and Interleukin-6 in Preoperative Prediction of Peritoneal Metastasis of Advanced Gastric Cancer | Full Text | References | PDF (5.2 MB) | EPUB
  • 191 Views
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Article
Decoding the Intercellular Cross-Talking Between Immune Cells and Renal Innate Cells in Diabetic Kidney Disease by Bioinformatics
Meng Zhou, Fang Lu, Ling Jiang, Chen Chen, Si Chen, Luhan Geng, Rui Sun, Qing Li, Suyan Duan, Bo Zhang, Huijuan Mao, Changying Xing & Yanggang Yuan
Pages: 3049-3062
Published online: 21 Jul 2023
AbstractforDecoding the Intercellular Cross-Talking Between Immune Cells and Renal Innate Cells in Diabetic Kidney Disease by Bioinformatics | Full Text | References | PDF (13.4 MB) | EPUB
  • 224 Views
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Article
Differential Characteristics of Patients for Hospitalized Severe COVID-19 Infected by the Omicron Variants and Wild Type of SARS-CoV-2 in China
Yuan-Yuan Wei, Rui-Rui Wang, Da-Wei Zhang, Su-Hong Chen, Yuan-Yuan Tan, Wen-Ting Zhang, Ming-Feng Han & Guang-He Fei
Pages: 3063-3078
Published online: 21 Jul 2023
AbstractforDifferential Characteristics of Patients for Hospitalized Severe COVID-19 Infected by the Omicron Variants and Wild Type of SARS-CoV-2 in China | Full Text | References | PDF (3.3 MB) | EPUB
  • 209 Views
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Original Research

Article
Screening of Potential Circulating Diagnostic Biomarkers and Molecular Mechanisms of Systemic Lupus Erythematosus-Related Myocardial Infarction by Integrative Analysis
Haoran Ding, Guoqi Zhu, Hao Lin, Jiapeng Chu, Deqiang Yuan, Yi’an Yao, Yanhua Gao, Fei Chen & Xuebo Liu
Pages: 3119-3134
Published online: 24 Jul 2023
AbstractforScreening of Potential Circulating Diagnostic Biomarkers and Molecular Mechanisms of Systemic Lupus Erythematosus-Related Myocardial Infarction by Integrative Analysis | Full Text | References | PDF (8.4 MB) | EPUB
  • 199 Views
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ORIGINAL RESEARCH

Article
Time-Related Vascular Inflammatory Response to COVID-19 Assessed by 18F-FDG PET/CT in Follow-Up Tumor Patients
Runlong Lin, Jing Yu, Aijuan Tian, Xiaomei Wang, Xin Yuan, Wengui Xu & Wenli Xie
Pages: 3109-3117
Published online: 24 Jul 2023
AbstractforTime-Related Vascular Inflammatory Response to COVID-19 Assessed by 18F-FDG PET/CT in Follow-Up Tumor Patients | Full Text | References | PDF (922.2 KB) | EPUB
  • 152 Views
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Article
Development of Prognostic Nomogram Based on Lipid Metabolic Markers and Lactate Dehydrogenase in Non-Metastatic Nasopharyngeal Carcinoma
Rong Huang, Kaihua Chen, Yuting Jiang, Ling Li & Xiaodong Zhu
Pages: 3093-3107
Published online: 24 Jul 2023
AbstractforDevelopment of Prognostic Nomogram Based on Lipid Metabolic Markers and Lactate Dehydrogenase in Non-Metastatic Nasopharyngeal Carcinoma | Full Text | References | PDF (6.5 MB) | EPUB
  • 137 Views
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Article
Neural Stem Cell-Derived Exosomes Improve Neurological Function in Rats with Cerebral Ischemia-Reperfusion Injury by Regulating Microglia-Mediated Inflammatory Response
Xue Zhao, Junde Zhu, Shan Chen, Ruojing Liu & Tingting Long
Pages: 3079-3092
Published online: 24 Jul 2023
AbstractforNeural Stem Cell-Derived Exosomes Improve Neurological Function in Rats with Cerebral Ischemia-Reperfusion Injury by Regulating Microglia-Mediated Inflammatory Response | Full Text | References | PDF (11.1 MB) | EPUB
  • 301 Views
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Article
Predictive Value of Perioperative Cardiac Troponin I in Patients Undergone Liver Transplantation: A Retrospective Cohort Study
Lei Zhang, Shu-Yan Guo, Guan Wang, Xi Zheng, Hui-Miao Jia, Li-Feng Huang, Yi-bing Weng & Wen-Xiong Li
Pages: 3135-3142
Published online: 24 Jul 2023
AbstractforPredictive Value of Perioperative Cardiac Troponin I in Patients Undergone Liver Transplantation: A Retrospective Cohort Study | Full Text | References | PDF (1.1 MB) | EPUB
  • 133 Views
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Article
Interactions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis
Haicheng Wang, Renbin Wang, Jingwen Yang, Yuan Feng, Shuyu Xu & Qing-Guo Pei
Pages: 3143-3156
Published online: 25 Jul 2023
AbstractforInteractions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis | Full Text | References | PDF (11.4 MB) | EPUB
  • 184 Views
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Article
Clinical Characteristics of Myasthenia Gravis Patients with COVID-19 in Guangxi, China: A Case–Control Study
Shaodan Zhou, Yishuang Wen, Chao Liu, Jian Zhong, Manli Liang, Yu Wu, Sirao Lv, Zhuowei Gong, Dayuan Lao, Taiyan Li, Ting Lu, Jingqun Tang, Xuean Mo & Wen Huang
Pages: 3157-3168
Published online: 26 Jul 2023
AbstractforClinical Characteristics of Myasthenia Gravis Patients with COVID-19 in Guangxi, China: A Case–Control Study | Full Text | References | PDF (1.7 MB) | EPUB
  • 173 Views
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Article
Immune Cell Infiltration Analysis Based on Bioinformatics Reveals Novel Biomarkers of Coronary Artery Disease
Tianwen He, Muheremu Muhetaer, Jiahe Wu, Jingjing Wan, Yushuang Hu, Tong Zhang, Yunxiang Wang, Qiongxin Wang, Huanhuan Cai & Zhibing Lu
Pages: 3169-3184
Published online: 26 Jul 2023
AbstractforImmune Cell Infiltration Analysis Based on Bioinformatics Reveals Novel Biomarkers of Coronary Artery Disease | Full Text | References | PDF (12 MB) | EPUB
  • 191 Views
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Article
Development and Validation of Nomogram for the Prediction of Malignant Ventricular Arrhythmia Including Circulating Inflammatory Cells in Patients with Acute ST-Segment Elevation Myocardial Infarction
Liang Wang, Liting Yang, Tao Li & Shanshan Geng
Pages: 3185-3196
Published online: 27 Jul 2023
AbstractforDevelopment and Validation of Nomogram for the Prediction of Malignant Ventricular Arrhythmia Including Circulating Inflammatory Cells in Patients with Acute ST-Segment Elevation Myocardial Infarction | Full Text | References | PDF (4.4 MB) | EPUB
  • 120 Views
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REVIEW

Review
Clinical Effect of Electroacupuncture on Acute Pancreatitis: Efficacies and Mechanisms
Xianqiang Yu & Qian Zhu
Pages: 3197-3203
Published online: 28 Jul 2023
AbstractforClinical Effect of Electroacupuncture on Acute Pancreatitis: Efficacies and Mechanisms | Full Text | References | PDF (1.2 MB) | EPUB
  • 199 Views
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ORIGINAL RESEARCH

Article
Single-Cell RNA Sequencing and Transcriptome Analysis Revealed the Immune Microenvironment and Gene Markers of Acute Respiratory Distress Syndrome
Dan He, Qiao Yu, Xiaona Zeng, Jihua Feng, Ruiqi Yang, Huan Wan, Ying Zhong, Yanli Yang, Ruzhi Zhao, Junyu Lu & Jianfeng Zhang
Pages: 3205-3217
Published online: 01 Aug 2023
AbstractforSingle-Cell RNA Sequencing and Transcriptome Analysis Revealed the Immune Microenvironment and Gene Markers of Acute Respiratory Distress Syndrome | Full Text | References | PDF (10.6 MB) | EPUB
  • 241 Views
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Article
Identification and Clinical Correlation Analysis of IFI44 in Systemic Lupus Erythematosus Combined with Bioinformatics and Immune Infiltration Analysis
Yuan Wang, Chengfeng Ma, Zhanbing Ma, Mengyi Yang, Jing Pu, Xiuhui Ma, Xi Wu, Liang Peng, Zhenghao Huo & Jie Dang
Pages: 3219-3231
Published online: 01 Aug 2023
AbstractforIdentification and Clinical Correlation Analysis of IFI44 in Systemic Lupus Erythematosus Combined with Bioinformatics and Immune Infiltration Analysis | Full Text | References | PDF (9.6 MB) | EPUB
  • 211 Views
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Article
The Prognostic Value of Blood Eosinophil Level in AECOPD is Influenced by Corticosteroid Treatment During Hospitalization
Jiachen Li, Lirong Liang, Lin Feng, Siyu Cao, Yutong Samuel Cai, Xiaobo Li, Zhenbei Qian, Christopher E Brightling & Zhaohui Tong
Pages: 3233-3243
Published online: 02 Aug 2023
AbstractforThe Prognostic Value of Blood Eosinophil Level in AECOPD is Influenced by Corticosteroid Treatment During Hospitalization | Full Text | References | PDF (3 MB) | EPUB
  • 224 Views
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Article
Electroacupuncture Alleviates Lung Injury in CpG1826-Challenged Mice via Modulating CD39-NLRP3 Pathway
Jiasi Wu, Xin Xiong & Xiumin Hu
Pages: 3245-3258
Published online: 03 Aug 2023
AbstractforElectroacupuncture Alleviates Lung Injury in CpG1826-Challenged Mice via Modulating CD39-NLRP3 Pathway | Full Text | References | PDF (10.1 MB) | EPUB
  • 153 Views
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REVIEW

Review
Interaction Between Blood Vasculatures and Lymphatic Vasculatures During Inflammation
Shun-Shun Wang, Xin-Xu Zhu, Xin-Yi Wu, Wen-Wu Zhang, Yang-Dong Ding, Sheng-Wei Jin & Pu-Hong Zhang
Pages: 3271-3281
Published online: 04 Aug 2023
AbstractforInteraction Between Blood Vasculatures and Lymphatic Vasculatures During Inflammation | Full Text | References | PDF (1.8 MB) | EPUB
  • 257 Views
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ORIGINAL RESEARCH

Article
Association Between Mean Platelet Volume and Benign Prostatic Hyperplasia: A Population Study from the TCLSIH Cohort Study
Yanqi Song, Yeqing Gu, Honglei Guo, Honghao Yang, Xuena Wang, Hongmei Wu, Aidi Wang, Mengxiao Wang, Haijin Wang, Qing Zhang, Li Liu, Ge Meng, Baoshan Liu & Kaijun Niu
Pages: 3259-3269
Published online: 05 Aug 2023
AbstractforAssociation Between Mean Platelet Volume and Benign Prostatic Hyperplasia: A Population Study from the TCLSIH Cohort Study | Full Text | References | PDF (1.8 MB) | EPUB
  • 185 Views
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Article
Identification of Immuno-Inflammation-Related Biomarkers for Acute Myocardial Infarction Based on Bioinformatics
Hongjun You & Mengya Dong
Pages: 3283-3302
Published online: 07 Aug 2023
AbstractforIdentification of Immuno-Inflammation-Related Biomarkers for Acute Myocardial Infarction Based on Bioinformatics | Full Text | References | PDF (18.3 MB) | EPUB
  • 268 Views
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Article
Identification of Hub Genes in the Pathogenesis of Bronchiolitis Obliterans via Bioinformatic Analysis and Experimental Verification
Zhongji Wu, Xiaowen Chen, Kangkang Zhang, Zhenwei Liu, Haidi Zhang, Zhaocong Zheng, Xiaodie Zhang, Yubiao Chen, Yinghui Peng, Hui Li, Kaiyin Huang, Sixiang Tang, Li Zhao & Dehui Chen
Pages: 3303-3317
Published online: 08 Aug 2023
AbstractforIdentification of Hub Genes in the Pathogenesis of Bronchiolitis Obliterans via Bioinformatic Analysis and Experimental Verification | Full Text | References | PDF (4.8 MB) | EPUB
  • 203 Views
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Article
Resolvin D1 Attenuates Inflammation and Pelvic Pain Associated with EAP by Inhibiting Oxidative Stress and NLRP3 Inflammasome Activation via the Nrf2/HO-1 Pathway
Jiong Zhang, Juan Chen, Qing Jiang, Rui Feng, Xiaohu Zhao, Haolin Li, Cheng Yang & Xiaoliang Hua
Pages: 3365-3379
Published online: 08 Aug 2023
AbstractforResolvin D1 Attenuates Inflammation and Pelvic Pain Associated with EAP by Inhibiting Oxidative Stress and NLRP3 Inflammasome Activation via the Nrf2/HO-1 Pathway | Full Text | References | PDF (13.4 MB) | EPUB
  • 248 Views
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Article
Pan-Immune-Inflammatory Value in Patients with Non-Small-Cell Lung Cancer Undergoing Neoadjuvant Immunochemotherapy
Wen-Yu Zhai, Fang-Fang Duan, Yao-Bin Lin, Yong-Bin Lin, Ze-Rui Zhao, Jun-Ye Wang, Bing-Yu Rao, Lie Zheng & Hao Long
Pages: 3329-3339
Published online: 08 Aug 2023
AbstractforPan-Immune-Inflammatory Value in Patients with Non-Small-Cell Lung Cancer Undergoing Neoadjuvant Immunochemotherapy | Full Text | References | PDF (2.8 MB) | EPUB
  • 198 Views
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Article
Comparison of Neoadjuvant Immunotherapy Plus Chemotherapy versus Neoadjuvant Chemoradiotherapy for Patients with Esophageal Squamous Cell Carcinoma: A Propensity Score Matching Study
Junfeng Zhao, Shaoyu Hao, Jing Tian, Ying Li & Dan Han
Pages: 3351-3363
Published online: 08 Aug 2023
AbstractforComparison of Neoadjuvant Immunotherapy Plus Chemotherapy versus Neoadjuvant Chemoradiotherapy for Patients with Esophageal Squamous Cell Carcinoma: A Propensity Score Matching Study | Full Text | References | PDF (4.6 MB) | EPUB
  • 197 Views
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CASE REPORT

Case Report
A Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome?
Tao Zhang, Zhu-Bin Pan, Wen-Jia Tong, Yu-Liang Zhou, Yuan Cheng, Dan-Qun Jin, Shi-Qin Qi & Zhen-Qiang Zhang
Pages: 3319-3327
Published online: 08 Aug 2023
AbstractforA Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome? | Full Text | References | PDF (3.4 MB) | EPUB
  • 130 Views
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ORIGINAL RESEARCH

Article
Proinflammatory and Immunomodulatory Gene and Protein Expression Patterns in Spinal Cord and Spleen Following Acute and Chronic High Thoracic Injury
Felicia M Michael, Samir P Patel, Adam D Bachstetter & Alexander G Rabchevsky
Pages: 3341-3349
Published online: 08 Aug 2023
AbstractforProinflammatory and Immunomodulatory Gene and Protein Expression Patterns in Spinal Cord and Spleen Following Acute and Chronic High Thoracic Injury | Full Text | References | PDF (4.1 MB) | EPUB
  • 193 Views
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Article
Comprehensive Analysis of SLC35A2 in Pan-Cancer and Validation of Its Role in Breast Cancer
Xiaonan Sun, Zhichao Yuan, Lu Zhang, Min Ren, Jing Yang, Yidan Xu & Jiqing Hao
Pages: 3381-3398
Published online: 11 Aug 2023
AbstractforComprehensive Analysis of SLC35A2 in Pan-Cancer and Validation of Its Role in Breast Cancer | Full Text | References | PDF (20 MB) | EPUB
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Article
Association of Systemic Inflammatory Response Index and Pan-Immune-Inflammation-Value with Long-Term Adverse Cardiovascular Events in ST-Segment Elevation Myocardial Infarction Patients After Primary Percutaneous Coronary Intervention
Yehong Liu, Jie Liu, Longqun Liu, Shaoqing Cao, Tianhui Jin, Liang Chen, Gangyong Wu & Gangjun Zong
Pages: 3437-3454
Published online: 14 Aug 2023
AbstractforAssociation of Systemic Inflammatory Response Index and Pan-Immune-Inflammation-Value with Long-Term Adverse Cardiovascular Events in ST-Segment Elevation Myocardial Infarction Patients After Primary Percutaneous Coronary Intervention | Full Text | References | PDF (4.6 MB) | EPUB
  • 308 Views
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Article
Amygdalin Delays Cartilage Endplate Degeneration and Improves Intervertebral Disc Degeneration by Inhibiting NF-κB Signaling Pathway and Inflammatory Response
Qinghe Zeng, Qi Sun, Huihui Xu, Jiali Chen, Houfu Ling, Qinwen Ge, Kaiao Zou, Xu Wang, Hongting Jin, Ju Li & Minwei Jin
Pages: 3455-3468
Published online: 14 Aug 2023
AbstractforAmygdalin Delays Cartilage Endplate Degeneration and Improves Intervertebral Disc Degeneration by Inhibiting NF-κB Signaling Pathway and Inflammatory Response | Full Text | References | PDF (9.5 MB) | EPUB
  • 204 Views
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Article
A Novel Neutrophil Extracellular Traps Signature for Overall Survival Prediction and Tumor Microenvironment Identification in Gastric Cancer
Ziting Qu, Yanxun Han, Qingbo Zhu, Wenxi Ding, Yuyan Wang, Yan Zhang, Wei Wei, Yu Lei, Min Li, Yang Jiao, Kangsheng Gu & Yiyin Zhang
Pages: 3419-3436
Published online: 14 Aug 2023
AbstractforA Novel Neutrophil Extracellular Traps Signature for Overall Survival Prediction and Tumor Microenvironment Identification in Gastric Cancer | Full Text | References | PDF (11.6 MB) | EPUB
  • 352 Views
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Article
Integrating Bulk and Single-Cell RNA Sequencing Reveals Heterogeneity, Tumor Microenvironment, and Immunotherapeutic Efficacy Based on Sialylation-Related Genes in Bladder Cancer
Zhiyong Tan, Xiaorong Chen, Jieming Zuo, Shi Fu, Jiansong Wang & Haifeng Wang
Pages: 3399-3417
Published online: 14 Aug 2023
AbstractforIntegrating Bulk and Single-Cell RNA Sequencing Reveals Heterogeneity, Tumor Microenvironment, and Immunotherapeutic Efficacy Based on Sialylation-Related Genes in Bladder Cancer | Full Text | References | PDF (21.4 MB) | EPUB
  • 262 Views
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Article
Subfatin, Asprosin, Alamandine and Maresin-1 Inflammation Molecules in Cardiopulmonary Bypass
Onur Hanbeyoglu & Suna Aydin
Pages: 3469-3477
Published online: 16 Aug 2023
AbstractforSubfatin, Asprosin, Alamandine and Maresin-1 Inflammation Molecules in Cardiopulmonary Bypass | Full Text | References | PDF (1.6 MB) | EPUB
  • 228 Views
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Article
Preoperative Systemic Immune-Inflammation Index is a Potential Biomarker in Adult Patients with High-Grade Gliomas Undergoing Radical Resection
Yu-Ting Jiang, Tian-Cheng Wang & Wei Zhang
Pages: 3479-3490
Published online: 16 Aug 2023
AbstractforPreoperative Systemic Immune-Inflammation Index is a Potential Biomarker in Adult Patients with High-Grade Gliomas Undergoing Radical Resection | Full Text | References | PDF (4.5 MB) | EPUB
  • 150 Views
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Article
Lymphocyte to C-Reactive Protein Ratio as an Early Biomarker to Distinguish Sepsis from Pneumonia in Neonates
Xinrui Liu & Yuan Mu
Pages: 3509-3517
Published online: 17 Aug 2023
AbstractforLymphocyte to C-Reactive Protein Ratio as an Early Biomarker to Distinguish Sepsis from Pneumonia in Neonates | Full Text | References | PDF (500.1 KB) | EPUB
  • 221 Views
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REVIEW

Review
Effects of Inflammatory Cell Death Caused by Catheter Ablation on Atrial Fibrillation
Dishiwen Liu, Yajia Li & Qingyan Zhao
Pages: 3491-3508
Published online: 17 Aug 2023
AbstractforEffects of Inflammatory Cell Death Caused by Catheter Ablation on Atrial Fibrillation | Full Text | References | PDF (3.2 MB) | EPUB
  • 292 Views
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ORIGINAL RESEARCH

Article
Analysis of Risk Factors and Intervention Strategies for Acute Kidney Injury After Cardiac Valve Replacement
Yi Jiang & Yanyan Song
Pages: 3523-3529
Published online: 18 Aug 2023
AbstractforAnalysis of Risk Factors and Intervention Strategies for Acute Kidney Injury After Cardiac Valve Replacement | Full Text | References | PDF (404.6 KB) | EPUB
  • 153 Views
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CASE REPORT

Case Report
Alopecia Universalis in an Elderly Chinese Man Induced by Sacubitril/Alisartan, a Novel Angiotensin Receptor-Neprilysin Inhibitor
Yan Teng, Yibin Fan, Danying Shang, Xiaohua Tao & Dongsheng Sun
Pages: 3519-3522
Published online: 19 Aug 2023
AbstractforAlopecia Universalis in an Elderly Chinese Man Induced by Sacubitril/Alisartan, a Novel Angiotensin Receptor-Neprilysin Inhibitor | Full Text | References | PDF (542.8 KB) | EPUB
  • 148 Views
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ORIGINAL RESEARCH

Article
Significance of Pyroptosis in Immunoregulation and Prognosis of Patients with Acute Respiratory Distress Syndrome: Evidence from RNA-Seq of Alveolar Macrophages
Bo Liu, Yan Li, Jinying Xiang, Yuehan Li, Mi Zhou, Yinying Ren, Zhou Fu & Fengxia Ding
Pages: 3547-3562
Published online: 21 Aug 2023
AbstractforSignificance of Pyroptosis in Immunoregulation and Prognosis of Patients with Acute Respiratory Distress Syndrome: Evidence from RNA-Seq of Alveolar Macrophages | Full Text | References | PDF (13.2 MB) | EPUB
  • 201 Views
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Article
Serological Biomarker-Based Machine Learning Models for Predicting the Relapse of Ulcerative Colitis
Wenwen Pang, Bowei Zhang, Leixin Jin, Yao Yao, Qiurong Han & Xiaoli Zheng
Pages: 3531-3545
Published online: 21 Aug 2023
AbstractforSerological Biomarker-Based Machine Learning Models for Predicting the Relapse of Ulcerative Colitis | Full Text | References | PDF (5.8 MB) | EPUB
  • 159 Views
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Article
Suppression of P2X7R by Local Treatment Alleviates Acute Gouty Inflammation
Yang Zhao, Zhiyuan Li, Ying Chen, Yushuang Li & Jie Lu
Pages: 3581-3591
Published online: 22 Aug 2023
AbstractforSuppression of P2X7R by Local Treatment Alleviates Acute Gouty Inflammation | Full Text | References | PDF (6.5 MB) | EPUB
  • 154 Views
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REVIEW

Review
Macrophage Polarization and the Regulation of Bone Immunity in Bone Homeostasis
Kangyi Hu, Zhengya Shang, Xiaorui Yang, Yongjie Zhang & Linzhong Cao
Pages: 3563-3580
Published online: 22 Aug 2023
AbstractforMacrophage Polarization and the Regulation of Bone Immunity in Bone Homeostasis | Full Text | References | PDF (3.2 MB) | EPUB
  • 476 Views
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ORIGINAL RESEARCH

Article
Advanced Lung Cancer Inflammation Index for Predicting Prognostic Risk for Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Xinchen Wang, Chen Wei, Wenjun Fan, Lixian Sun, Ying Zhang, Qiyu Sun, Yixiang Liu & Jingyi Liu
Pages: 3631-3641
Published online: 23 Aug 2023
AbstractforAdvanced Lung Cancer Inflammation Index for Predicting Prognostic Risk for Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention | Full Text | References | PDF (4.4 MB) | EPUB
  • 166 Views
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Article
The Association of the Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Lymphocyte-to-Monocyte Ratio and Systemic Inflammation Response Index with Short-Term Functional Outcome in Patients with Acute Ischemic Stroke
Ya Xin Zhang, Zhi Yuan Shen, Yi Cun Jia, Xin Guo, Xiao Su Guo, Yuan Xing & Shu Juan Tian
Pages: 3619-3630
Published online: 23 Aug 2023
AbstractforThe Association of the Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Lymphocyte-to-Monocyte Ratio and Systemic Inflammation Response Index with Short-Term Functional Outcome in Patients with Acute Ischemic Stroke | Full Text | References | PDF (775.8 KB) | EPUB
  • 185 Views
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Article
Association of Inflammatory Indicators and Clinical Signs and Itch in Atopic Dermatitis Patients Treated with Simiao Pill Combined with Halomethasone Cream
Jun Cao, Hui Liu & Xiaojie Ding
Pages: 3643-3653
Published online: 23 Aug 2023
AbstractforAssociation of Inflammatory Indicators and Clinical Signs and Itch in Atopic Dermatitis Patients Treated with Simiao Pill Combined with Halomethasone Cream | Full Text | References | PDF (2 MB) | EPUB
  • 162 Views
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Article
Esculetin Alleviates Inflammation, Oxidative Stress and Apoptosis in Intestinal Ischemia/Reperfusion Injury via Targeting SIRT3/AMPK/mTOR Signaling and Regulating Autophagy
Xin Shen, Hai Shi, Xinli Chen, Junwei Han, Haiwang Liu, Jie Yang, Yuan Shi & Jiajia Ma
Pages: 3655-3667
Published online: 23 Aug 2023
AbstractforEsculetin Alleviates Inflammation, Oxidative Stress and Apoptosis in Intestinal Ischemia/Reperfusion Injury via Targeting SIRT3/AMPK/mTOR Signaling and Regulating Autophagy | Full Text | References | PDF (10.9 MB) | EPUB
  • 185 Views
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REVIEW

Review
Research Progress and Molecular Mechanisms of Endothelial Cells Inflammation in Vascular-Related Diseases
Jiaojiao Xue, Ziwei Zhang, Yuting Sun, Di Jin, Liming Guo, Xiangyan Li, Daqing Zhao, Xiaochun Feng, Wenxiu Qi & Haoyu Zhu
Pages: 3593-3617
Published online: 23 Aug 2023
AbstractforResearch Progress and Molecular Mechanisms of Endothelial Cells Inflammation in Vascular-Related Diseases | Full Text | References | PDF (2.8 MB) | EPUB
  • 333 Views
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ORIGINAL RESEARCH

Article
Therapeutic Effects of HLA-G5 Overexpressing hAMSCs on aGVHD After Allo-HSCT: Involving in the Gut Microbiota at the Intestinal Barrier
Xiaoyin Bu, Weifeng Pan, Junhui Wang, Liping Liu, Zhao Yin, Hua Jin, Qifa Liu, Lei Zheng, Haitao Sun, Ya Gao & Baohong Ping
Pages: 3669-3685
Published online: 24 Aug 2023
AbstractforTherapeutic Effects of HLA-G5 Overexpressing hAMSCs on aGVHD After Allo-HSCT: Involving in the Gut Microbiota at the Intestinal Barrier | Full Text | References | PDF (10.2 MB) | EPUB
  • 210 Views
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Article
Differential Expression Profiles of Plasma Exosomal microRNAs in Rheumatoid Arthritis
Xiaoke Yang, Zhixin Wang, Mingming Zhang & Zongwen Shuai
Pages: 3687-3698
Published online: 28 Aug 2023
AbstractforDifferential Expression Profiles of Plasma Exosomal microRNAs in Rheumatoid Arthritis | Full Text | References | PDF (4.2 MB) | EPUB
  • 171 Views
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CASE REPORT

Case Report
Ulcerative Colitis Concomitant with Cytomegalovirus Infection, Bullous Sweet’s Syndrome, and Acute Myeloid Leukemia: A Case Report and Literature Review
Fengqin Zhu, Zongjing Hu, Wei Yu, Fengxian Dai, Dehuai Jing & Guangxi Zhou
Pages: 3715-3723
Published online: 28 Aug 2023
AbstractforUlcerative Colitis Concomitant with Cytomegalovirus Infection, Bullous Sweet’s Syndrome, and Acute Myeloid Leukemia: A Case Report and Literature Review | Full Text | References | PDF (2 MB) | EPUB
  • 165 Views
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ORIGINAL RESEARCH

Article
Integrated Analysis Identifies Upregulated SAMD9L as a Potential Biomarker Correlating with the Severity of Primary Sjögren’s Syndrome
Donghai Zhou, Xue Yu, Kai Yu, Yating Ren, Kepeng Yang, Xinchang Wang & Qiao Wang
Pages: 3725-3738
Published online: 28 Aug 2023
AbstractforIntegrated Analysis Identifies Upregulated SAMD9L as a Potential Biomarker Correlating with the Severity of Primary Sjögren’s Syndrome | Full Text | References | PDF (10 MB) | EPUB
  • 168 Views
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Article
TMAO Promotes NLRP3 Inflammasome Activation of Microglia Aggravating Neurological Injury in Ischemic Stroke Through FTO/IGF2BP2
Pengxin Ge, Huijie Duan, Chunrong Tao, Sensen Niu, Yiran Hu, Rui Duan, Aizong Shen, Yancai Sun & Wen Sun
Pages: 3699-3714
Published online: 28 Aug 2023
AbstractforTMAO Promotes NLRP3 Inflammasome Activation of Microglia Aggravating Neurological Injury in Ischemic Stroke Through FTO/IGF2BP2 | Full Text | References | PDF (7 MB) | EPUB
  • 347 Views
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Article
Serum Amyloid A 4 as a Common Marker of Persistent Inflammation in Patients with Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy
Qingyan Liu, Shuo Sun, Zhengwei Yang, Yan Shao & Xiaorong Li
Pages: 3783-3797
Published online: 29 Aug 2023
AbstractforSerum Amyloid A 4 as a Common Marker of Persistent Inflammation in Patients with Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy | Full Text | References | PDF (6.9 MB) | EPUB
  • 158 Views
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Article
Polyhydroxylated Fullerene C60(OH)40 Nanofilms Promote the Mesenchymal–Epithelial Transition of Human Liver Cancer Cells via the TGF-β1/Smad Pathway
Malwina Sosnowska, Marta Kutwin, Piotr Koczoń, André Chwalibog & Ewa Sawosz
Pages: 3739-3761
Published online: 29 Aug 2023
AbstractforPolyhydroxylated Fullerene C60(OH)40 Nanofilms Promote the Mesenchymal–Epithelial Transition of Human Liver Cancer Cells via the TGF-β1/Smad Pathway | Full Text | References | PDF (11.3 MB) | EPUB
  • 275 Views
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Article
Characteristics of Autophagy-Related Genes, Diagnostic Models, and Their Correlation with Immune Infiltration in Keratoconus
Yi Liu, Xu Yang, Huan Li, Dongfeng Li, Yuhao Zou, Bo Gong & Man Yu
Pages: 3763-3781
Published online: 29 Aug 2023
AbstractforCharacteristics of Autophagy-Related Genes, Diagnostic Models, and Their Correlation with Immune Infiltration in Keratoconus | Full Text | References | PDF (15.4 MB) | EPUB
  • 136 Views
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Article
NUP62CL as an Immunological and Prognostic Biomarker of Oral Squamous Cell Carcinoma
Xin Yu, Lijun Xu, Yongqiang Zhou, Xiaorong Zhou, Lei Yang & Yan Zhou
Pages: 3799-3809
Published online: 29 Aug 2023
AbstractforNUP62CL as an Immunological and Prognostic Biomarker of Oral Squamous Cell Carcinoma | Full Text | References | PDF (7.5 MB) | EPUB
  • 152 Views
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Article
Serum Metabolomics Analysis of Skin-Involved Systemic Lupus Erythematosus: Association of Anti-SSA Antibodies with Photosensitivity
Dingqi Lu, Xinchao Zhu, Tao Hong, Xinyi Yao, Zhiming Xie, Liying Chen, Yihan Wang, Kaiyuan Zhang, Yating Ren, Yi Cao & Xinchang Wang
Pages: 3811-3822
Published online: 30 Aug 2023
AbstractforSerum Metabolomics Analysis of Skin-Involved Systemic Lupus Erythematosus: Association of Anti-SSA Antibodies with Photosensitivity | Full Text | References | PDF (6.1 MB) | EPUB
  • 206 Views
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Article
Resveratrol Ameliorates Imiquimod-Induced Psoriasis-Like Mouse Model via Reducing Macrophage Infiltration and Inhibiting Glycolysis
Yazhuo Wang, Cong Qi, Fang Feng, Xueqing Hu, Ning Zhao, Jingxia Zhao, Tingting Di, Yujiao Meng, Danyang Yang, Haoyue Zhu, Xiawei Zhang, Ping Li & Yan Wang
Pages: 3823-3836
Published online: 30 Aug 2023
AbstractforResveratrol Ameliorates Imiquimod-Induced Psoriasis-Like Mouse Model via Reducing Macrophage Infiltration and Inhibiting Glycolysis | Full Text | References | PDF (8.2 MB) | EPUB
  • 335 Views
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Article
Identification and Analysis of Neutrophil Extracellular Trap-Related Genes in Osteoarthritis by Bioinformatics and Experimental Verification
Tiankuo Luan, Xian Yang, Ge Kuang, Ting Wang, Jiaming He, Zhibo Liu, Xia Gong, Jingyuan Wan & Ke Li
Pages: 3837-3852
Published online: 31 Aug 2023
AbstractforIdentification and Analysis of Neutrophil Extracellular Trap-Related Genes in Osteoarthritis by Bioinformatics and Experimental Verification | Full Text | References | PDF (13.4 MB) | EPUB
  • 268 Views
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Article
Systemic Immune-Inflammation Index Was Significantly Associated with All-Cause and Cardiovascular-Specific Mortalities in Patients Receiving Peritoneal Dialysis
Guanglan Li, Jing Yu, Simin Jiang, Kefei Wu, Yiping Xu, Xiaohui Lu, Yating Wang, Jianxiong Lin, Xiao Yang, Zhibin Li & Haiping Mao
Pages: 3871-3878
Published online: 31 Aug 2023
AbstractforSystemic Immune-Inflammation Index Was Significantly Associated with All-Cause and Cardiovascular-Specific Mortalities in Patients Receiving Peritoneal Dialysis | Full Text | References | PDF (2.5 MB) | EPUB
  • 181 Views
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Article
The Mechanisms of Resistin-Like Molecule-β-Mediated Airway Inflammation in Chronic Obstructive Pulmonary Disease via Autophagy
Li Che, Zhefan Xie, Guangshu Chen, Wei Zhang, Tingting Xia, Jiaxin Lin, Wenzhi Luo, Li Chen, Wenguang Yin, Xingdong Cai & Shengming Liu
Pages: 3853-3870
Published online: 31 Aug 2023
AbstractforThe Mechanisms of Resistin-Like Molecule-β-Mediated Airway Inflammation in Chronic Obstructive Pulmonary Disease via Autophagy | Full Text | References | PDF (12.1 MB) | EPUB
  • 177 Views
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REVIEW

Review
Programmed Cell Death in Liver Fibrosis
Ruoyu Gao, Haiying Tang & Jingwei Mao
Pages: 3897-3910
Published online: 01 Sep 2023
AbstractforProgrammed Cell Death in Liver Fibrosis | Full Text | References | PDF (3.5 MB) | EPUB
  • 226 Views
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ORIGINAL RESEARCH

Article
Integrated Analysis of Non-Coding RNA and mRNA Expression Profiles in Exosomes from Lung Tissue with Sepsis-Induced Acute Lung Injury
Wei Deng, Yanhua Lu, Ping Hu, Qingqing Zhang, Shuangyan Li, Dong Yang, Ning Zhao, Kejian Qian & Fen Liu
Pages: 3879-3895
Published online: 01 Sep 2023
AbstractforIntegrated Analysis of Non-Coding RNA and mRNA Expression Profiles in Exosomes from Lung Tissue with Sepsis-Induced Acute Lung Injury | Full Text | References | PDF (11.6 MB) | EPUB
  • 188 Views
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Article
Inflammatory Burden Index: Association Between Novel Systemic Inflammatory Biomarkers and Prognosis as Well as in-Hospital Complications of Patients with Aneurysmal Subarachnoid Hemorrhage
Zhenshan Song, Fa Lin, Yu Chen, Tu Li, Runting Li, Junlin Lu, Heze Han, Ruinan Li, Jun Yang, Zhipeng Li, Haibin Zhang, Kexin Yuan, Ke Wang, Yunfan Zhou, Yitong Jia & Xiaolin Chen
Pages: 3911-3921
Published online: 04 Sep 2023
AbstractforInflammatory Burden Index: Association Between Novel Systemic Inflammatory Biomarkers and Prognosis as Well as in-Hospital Complications of Patients with Aneurysmal Subarachnoid Hemorrhage | Full Text | References | PDF (4 MB) | EPUB
  • 135 Views
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Article
Serum Protein Profiling Reveals a Decrease in Apolipoprotein A-IV During a Clinical Depressive Mood State
Sora Mun, Seungyeon Lee, Yeeun Yun, Eun-Jeong Joo, Hee-Gyoo Kang & Jiyeong Lee
Pages: 3925-3936
Published online: 05 Sep 2023
AbstractforSerum Protein Profiling Reveals a Decrease in Apolipoprotein A-IV During a Clinical Depressive Mood State | Full Text | References | PDF (4.1 MB) | EPUB
  • 173 Views
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CORRIGENDUM

Correction
General Theory of Inflammation: Patient Self-Administration of Hydrocortisone Safely Achieves Superior Control of Hydrocortisone-Responding Disorders by Matching Dosage with Symptom Intensity [Corrigendum]
Pages: 3923-3924
Published online: 05 Sep 2023
CitationforGeneral Theory of Inflammation: Patient Self-Administration of Hydrocortisone Safely Achieves Superior Control of Hydrocortisone-Responding Disorders by Matching Dosage with Symptom Intensity [Corrigendum] | Full Text | PDF (232.2 KB) | EPUB
  • 90 Views
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REVIEW

Review
Advances in the Study of Immunosuppressive Mechanisms in Sepsis
Xuzhe Fu, Zhi Liu & Yu Wang
Pages: 3967-3981
Published online: 08 Sep 2023
AbstractforAdvances in the Study of Immunosuppressive Mechanisms in Sepsis | Full Text | References | PDF (2.4 MB) | EPUB
  • 246 Views
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Review
Potential Mechanism of Fatigue Induction and Its Management by JAK Inhibitors in Inflammatory Rheumatic Diseases
Anna Felis-Giemza, Magdalena Massalska, Leszek Roszkowski, Katarzyna Romanowska-Próchnicka & Marzena Ciechomska
Pages: 3949-3965
Published online: 08 Sep 2023
AbstractforPotential Mechanism of Fatigue Induction and Its Management by JAK Inhibitors in Inflammatory Rheumatic Diseases | Full Text | References | PDF (1.7 MB) | EPUB
  • 250 Views
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ORIGINAL RESEARCH

Article
The Effect of Decrease in Serum Urate for the Risk of Gout Flares During Urate-Lowering Therapy Initiation Among Chinese Male Gout Patients: A Prospective Cohort Study
Lei Pang, Xiaomei Xue, Yuwei He, Can Wang, Lin Han, Maichao Li, Han Qi, Changgui Li & Jie Lu
Pages: 3937-3947
Published online: 08 Sep 2023
AbstractforThe Effect of Decrease in Serum Urate for the Risk of Gout Flares During Urate-Lowering Therapy Initiation Among Chinese Male Gout Patients: A Prospective Cohort Study | Full Text | References | PDF (3.3 MB) | EPUB
  • 167 Views
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Article
Diagnosis of Early Bacterial Pneumonia and Sepsis After Cardiovascular Surgery: A Diagnostic Prediction Model Based on LASSO Logistic Regression
Hai-Tao Zhang, Kuo Wang, Ze-Shi Li, Chuang-Shi Wang, Xi-Kun Han, Wei Chen, Fu-Dong Fan, Jun Pan, Qing Zhou, Hai-Long Cao, Hao-Dong Pan, Xiateke Hafu, Chen Li, Guo-Liang Fan, Tuo Pan, Dong-Jin Wang & Wei Wang
Pages: 3983-3996
Published online: 11 Sep 2023
AbstractforDiagnosis of Early Bacterial Pneumonia and Sepsis After Cardiovascular Surgery: A Diagnostic Prediction Model Based on LASSO Logistic Regression | Full Text | References | PDF (1.5 MB) | EPUB
  • 202 Views
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Article
Pan-Cancer Analysis of Oncogenic Role of RAD54L and Experimental Validation in Hepatocellular Carcinoma
Yongzhen Zhou, Chenjie Qiu, Qingsheng Fu, Tao Li, Xudong Zhang, Chunfu Zhu, Xihu Qin & Baoqiang Wu
Pages: 3997-4017
Published online: 11 Sep 2023
AbstractforPan-Cancer Analysis of Oncogenic Role of RAD54L and Experimental Validation in Hepatocellular Carcinoma | Full Text | References | PDF (15.4 MB) | EPUB
  • 244 Views
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Article
Association Between Systemic Immune Inflammation Level and Poor Prognosis Across Different Glucose Metabolism Status in Coronary Artery Disease Patients
Xiayan Xu, Yun Xie, Xia Gu, Yang Zhou, Yu Kang, Jin Liu, Wenguang Lai, Hongyu Lu, Shiqun Chen, Jun-yan Xu, Feng Lin & Yong Liu
Pages: 4031-4042
Published online: 12 Sep 2023
AbstractforAssociation Between Systemic Immune Inflammation Level and Poor Prognosis Across Different Glucose Metabolism Status in Coronary Artery Disease Patients | Full Text | References | PDF (3 MB) | EPUB
  • 169 Views
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Article
Fibrinogen is Associated with Clinical Adverse Events in Patients with Psoriasis and Coronary Artery Disease
Lin Zhao, Yan Zeng, Lin Sun, ZengLei Zhang, KunQi Yang, ZuoZhi Li, Man Wang, XianLiang Zhou & WeiXian Yang
Pages: 4019-4030
Published online: 12 Sep 2023
AbstractforFibrinogen is Associated with Clinical Adverse Events in Patients with Psoriasis and Coronary Artery Disease | Full Text | References | PDF (951.4 KB) | EPUB
  • 154 Views
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Article
An Easy-to-Use Nomogram Based on SII and SIRI to Predict in-Hospital Mortality Risk in Elderly Patients with Acute Myocardial Infarction
Yan Chen, Kailing Xie, Yuanyuan Han, Qing Xu & Xin Zhao
Pages: 4061-4071
Published online: 13 Sep 2023
AbstractforAn Easy-to-Use Nomogram Based on SII and SIRI to Predict in-Hospital Mortality Risk in Elderly Patients with Acute Myocardial Infarction | Full Text | References | PDF (4.1 MB) | EPUB
  • 175 Views
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Article
Integrated Analysis of Immune Infiltration and Hub Pyroptosis-Related Genes for Multiple Sclerosis
Shaoru Zhang, Yue Ma, Xiaoqin Luo, Hongmei Xiao, Ruiqi Cheng, Anan Jiang & Xinyue Qin
Pages: 4043-4059
Published online: 13 Sep 2023
AbstractforIntegrated Analysis of Immune Infiltration and Hub Pyroptosis-Related Genes for Multiple Sclerosis | Full Text | References | PDF (13.2 MB) | EPUB
  • 178 Views
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REVIEW

Review
The Emerging Roles of Ferroptosis in Pathophysiology and Treatment of Acute Lung Injury
Yufei Wang, Zijun Zhao & Zhaoyang Xiao
Pages: 4073-4085
Published online: 14 Sep 2023
AbstractforThe Emerging Roles of Ferroptosis in Pathophysiology and Treatment of Acute Lung Injury | Full Text | References | PDF (2.8 MB) | EPUB
  • 222 Views
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ORIGINAL RESEARCH

Article
HDAC1 is Involved in Neuroinflammation and Blood-Brain Barrier Damage in Stroke Pathogenesis
Hao-Kuang Wang, Yu-Ting Su, Yu-Cheng Ho, Yung-Kuo Lee, Tian-Huei Chu, Kuang-Ti Chen & Cheng-Chun Wu
Pages: 4103-4116
Published online: 18 Sep 2023
AbstractforHDAC1 is Involved in Neuroinflammation and Blood-Brain Barrier Damage in Stroke Pathogenesis | Full Text | References | PDF (7.6 MB) | EPUB
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REVIEW

Review
An Overview of the Mechanisms Involved in Neuralgia
Bai-Wen Zhang, Hao Dong, Zhe Wu, Xi Jiang & Wei Zou
Pages: 4087-4101
Published online: 18 Sep 2023
AbstractforAn Overview of the Mechanisms Involved in Neuralgia | Full Text | References | PDF (2.1 MB) | EPUB
  • 190 Views
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CASE REPORT

Case Report
Concurrent Polycythemia Vera with Newly Diagnosed Multiple Myeloma: Case Report and Literature Review
Jing Yuan, Xuan Liu, Zhenzhen Wang, Liyuan Li & Fuxu Wang
Pages: 4117-4121
Published online: 18 Sep 2023
AbstractforConcurrent Polycythemia Vera with Newly Diagnosed Multiple Myeloma: Case Report and Literature Review | Full Text | References | PDF (458.2 KB) | EPUB
  • 148 Views
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ORIGINAL RESEARCH

Article
Total Flavonoids of Rhizoma Drynariae Treat Osteoarthritis by Inhibiting Arachidonic Acid Metabolites Through AMPK/NFκB Pathway
Guang-Yao Chen, Xiao-Yu Liu, Xue-Er Yan, XinBo Yu, Yi Liu, Jing Luo & Qing-Wen Tao
Pages: 4123-4140
Published online: 20 Sep 2023
AbstractforTotal Flavonoids of Rhizoma Drynariae Treat Osteoarthritis by Inhibiting Arachidonic Acid Metabolites Through AMPK/NFκB Pathway | Full Text | References | PDF (9.9 MB) | EPUB
  • 197 Views
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Article
Prophylactic Treatment of Intestinal Ischemia-Reperfusion Injury Reduces Mucosal Damage and Improves Intestinal Absorption
Ignacio Garcia-Alonso, Xabier Velasco-Oraa, Iñigo Cearra, Sira Iturrizaga Correcher, Carmen Mar Medina, Ana Alonso-Varona, Amador García Ruiz de Gordejuela, Inmaculada Ruiz-Montesinos & Borja Herrero de la Parte
Pages: 4141-4152
Published online: 20 Sep 2023
AbstractforProphylactic Treatment of Intestinal Ischemia-Reperfusion Injury Reduces Mucosal Damage and Improves Intestinal Absorption | Full Text | References | PDF (3.7 MB) | EPUB
  • 188 Views
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Article
GBP5 Expression Predicted Prognosis of Immune Checkpoint Inhibitors in Small Cell Lung Cancer and Correlated with Tumor Immune Microenvironment
Qin Tong, Deyu Li, Yan Yin, Lifang Cheng & Shuming Ouyang
Pages: 4153-4164
Published online: 20 Sep 2023
AbstractforGBP5 Expression Predicted Prognosis of Immune Checkpoint Inhibitors in Small Cell Lung Cancer and Correlated with Tumor Immune Microenvironment | Full Text | References | PDF (3 MB) | EPUB
  • 129 Views
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REVIEW

Review
Mesenchymal Stem Cell-Derived Exosomes: A Novel Approach to Diabetes-Associated Cognitive Impairment
Qingsen Ran, He Tian, Jian Lin, Han Wang, Bo Wang, Zhixin Chen, Da Song & Chunzhu Gong
Pages: 4213-4228
Published online: 21 Sep 2023
AbstractforMesenchymal Stem Cell-Derived Exosomes: A Novel Approach to Diabetes-Associated Cognitive Impairment | Full Text | References | PDF (2.8 MB) | EPUB
  • 293 Views
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Review
Non-Coding RNA in Microglia Activation and Neuroinflammation in Alzheimer’s Disease
Chunxiang He, Ze Li, Miao Yang, Wenjing Yu, Rongsiqing Luo, Jinyong Zhou, Jiawei He, Qi Chen, Zhenyan Song & Shaowu Cheng
Pages: 4165-4211
Published online: 21 Sep 2023
AbstractforNon-Coding RNA in Microglia Activation and Neuroinflammation in Alzheimer’s Disease | Full Text | References | PDF (4 MB) | EPUB
  • 416 Views
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ORIGINAL RESEARCH

Article
Prognostic Value of Combined LMR and CEA Dynamic Monitoring in Postoperative Colorectal Cancer Patients
Shan Chen, Jie Zhang, Chengjia Qian, Xiaowei Qi, Yong Mao & Tingxun Lu
Pages: 4229-4250
Published online: 22 Sep 2023
AbstractforPrognostic Value of Combined LMR and CEA Dynamic Monitoring in Postoperative Colorectal Cancer Patients | Full Text | References | PDF (5.5 MB) | EPUB
  • 127 Views
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Article
Radix Salvia miltiorrhiza Ameliorates Burn Injuries by Reducing Inflammation and Promoting Wound Healing
Shuo Tian, Lin Guo, Yagang Song, Huiyan Yang, Jia Wang, Jingyi Qiao, Xiangxiang Wu, Ming Bai & Mingsan Miao
Pages: 4251-4263
Published online: 25 Sep 2023
AbstractforRadix Salvia miltiorrhiza Ameliorates Burn Injuries by Reducing Inflammation and Promoting Wound Healing | Full Text | References | PDF (11.1 MB) | EPUB
  • 182 Views
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Article
NAMPT/SIRT1 Expression Levels in White Blood Cells Differentiate the Different Rheumatoid Arthritis Subsets: An Inspiration from Traditional Chinese Medicine
Xiu-Ping Cheng, Xiao-Wan Wang, Han-Fei Sun, Liang Xu, Opeyemi Joshua Olatunji, Yan Li, Jia-Ting Lin & Jian Zuo
Pages: 4271-4285
Published online: 26 Sep 2023
AbstractforNAMPT/SIRT1 Expression Levels in White Blood Cells Differentiate the Different Rheumatoid Arthritis Subsets: An Inspiration from Traditional Chinese Medicine | Full Text | References | PDF (11.5 MB) | EPUB
  • 200 Views
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CASE REPORT

Case Report
A Case of Postnatal Aortic Arch Atresia
Zi-Xin Yang, Ying Han, Jie Zhang, Yong-Hui Yu & Mei Zhu
Pages: 4265-4270
Published online: 26 Sep 2023
AbstractforA Case of Postnatal Aortic Arch Atresia | Full Text | References | PDF (1.9 MB) | EPUB
  • 95 Views
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ORIGINAL RESEARCH

Article
Umbilical Cord Stem Cell Lysate: A New Biologic Injectate for the Putative Treatment of Acute Temporomandibular Joint Inflammation
Christopher K Ward, Rita G Gill, Robert S Liddell & John E Davies
Pages: 4287-4300
Published online: 27 Sep 2023
AbstractforUmbilical Cord Stem Cell Lysate: A New Biologic Injectate for the Putative Treatment of Acute Temporomandibular Joint Inflammation | Full Text | References | PDF (5.6 MB) | EPUB
  • 199 Views
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REVIEW

Review
The Role of Inflammation-Associated Factors in Head and Neck Squamous Cell Carcinoma
Kang Li, Xianhai Zeng, Peng Liu, Xiaoxia Zeng, Jie Lv, Shuqi Qiu & Peng Zhang
Pages: 4301-4315
Published online: 27 Sep 2023
AbstractforThe Role of Inflammation-Associated Factors in Head and Neck Squamous Cell Carcinoma | Full Text | References | PDF (2.4 MB) | EPUB
  • 144 Views
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ORIGINAL RESEARCH

Article
Identification and Validation of Signature Genes and Potential Therapy Targets of Inflammatory Bowel Disease and Periodontitis
Zhe Xiong, Ying Fang, Shuangshuang Lu, Qiuyue Sun & Jin Huang
Pages: 4317-4330
Published online: 28 Sep 2023
AbstractforIdentification and Validation of Signature Genes and Potential Therapy Targets of Inflammatory Bowel Disease and Periodontitis | Full Text | References | PDF (11.3 MB) | EPUB
  • 218 Views
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Article
The Disease Experience of Women with Granulomatous Lobular Mastitis. A Qualitative Interview Study
Yan Ting Wang, Ya Qin Tang, Jia Yuan Xu & Xue Mei Bian
Pages: 4347-4361
Published online: 28 Sep 2023
AbstractforThe Disease Experience of Women with Granulomatous Lobular Mastitis. A Qualitative Interview Study | Full Text | References | PDF (466.3 KB) | EPUB
  • 206 Views
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Article
Xianglian Zhixie Tablet Antagonizes Dextran Sulfate Sodium-Induced Ulcerative Colitis by Attenuating Systemic Inflammation and Modulating Gut Microbiota
Yilin Li, Tingting Wang, Beibei Ma, Shangyue Yu, Hailuan Pei, Shiqiu Tian, Yingying Tian, Chuang Liu, Xinyue Zhao, Zeping Zuo & Zhibin Wang
Pages: 4331-4346
Published online: 28 Sep 2023
AbstractforXianglian Zhixie Tablet Antagonizes Dextran Sulfate Sodium-Induced Ulcerative Colitis by Attenuating Systemic Inflammation and Modulating Gut Microbiota | Full Text | References | PDF (11.5 MB) | EPUB
  • 131 Views
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REVIEW

Review
Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
Xuejun Tan, Yukun Xu, Sirui Zhou, Mingyue Pan, Yue Cao, Xiuping Cai, Qing Zhao & Kewei Zhao
Pages: 4363-4372
Published online: 29 Sep 2023
AbstractforAdvances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases | Full Text | References | PDF (2.7 MB) | EPUB
  • 246 Views
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ORIGINAL RESEARCH

Article
Clinical Significance of Fibrinogen and Platelet to Pre-Albumin Ratio in Predicting the Prognosis of Advanced Gastric Cancer
Huakai Tian, Zitao Liu, Zuo Zhang, Lipeng Zhang, Zhen Zong, Jiang Liu, Houqun Ying & Hui Li
Pages: 4373-4388
Published online: 02 Oct 2023
AbstractforClinical Significance of Fibrinogen and Platelet to Pre-Albumin Ratio in Predicting the Prognosis of Advanced Gastric Cancer | Full Text | References | PDF (9.2 MB) | EPUB
  • 146 Views
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REVIEW

Review
Mesenchymal Stem Cells in Heterotopic Ossification in Ankylosing Spondylitis: A Bibliometric Study Based on CiteSpace and VOSViewer
Zhaoyi Liu, Qing Yu & Hongxiao Liu
Pages: 4389-4398
Published online: 04 Oct 2023
AbstractforMesenchymal Stem Cells in Heterotopic Ossification in Ankylosing Spondylitis: A Bibliometric Study Based on CiteSpace and VOSViewer | Full Text | References | PDF (5.7 MB) | EPUB
  • 114 Views
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ORIGINAL RESEARCH

Article
Andrographolide Attenuates Inflammation Due to Intra-Abdominal Sepsis by Enhancing Bacterial Clearance in Mice
Lechang Yu, Ying Liu, Chao Cao, Liheng Yang, Haijing Liu & Chunli Wang
Pages: 4413-4423
Published online: 06 Oct 2023
AbstractforAndrographolide Attenuates Inflammation Due to Intra-Abdominal Sepsis by Enhancing Bacterial Clearance in Mice | Full Text | References | PDF (5.2 MB) | EPUB
  • 125 Views
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Article
An in-Depth Exploration of the Genetic Interaction Network Between Ferroptosis and Acute Pancreatitis
Jie Li, Yuchen Jia, Feng Cao, Gang Wang & Fei Li
Pages: 4425-4439
Published online: 06 Oct 2023
AbstractforAn in-Depth Exploration of the Genetic Interaction Network Between Ferroptosis and Acute Pancreatitis | Full Text | References | PDF (17.7 MB) | EPUB
  • 139 Views
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Article
Development and External Validation of a Nomogram for Predicting the Effect of RTX on the Treatment of Membranous Nephropathy
Yanhong Guo, Mingjing Ren, Xinxin Pang, Yulin Wang, Lu Yu & Lin Tang
Pages: 4399-4411
Published online: 06 Oct 2023
AbstractforDevelopment and External Validation of a Nomogram for Predicting the Effect of RTX on the Treatment of Membranous Nephropathy | Full Text | References | PDF (7.8 MB) | EPUB
  • 81 Views
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Article
Higher High-Mobility Group Box-1 Levels are Associated with White Matter Lesions in Ischemic Stroke Patients
Jie Zhao, Fang Xu, Wanying Xu, Rong Lv, Juan Wang & Xufeng Yang
Pages: 4441-4449
Published online: 09 Oct 2023
AbstractforHigher High-Mobility Group Box-1 Levels are Associated with White Matter Lesions in Ischemic Stroke Patients | Full Text | References | PDF (1.1 MB) | EPUB
  • 83 Views
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Article
Correlation Between Systemic Immune-Inflammation Index and Suicide Attempts in Children and Adolescents with First-Episode, Drug-Naïve Major Depressive Disorder During the COVID-19 Pandemic
Shu Cui, Zhiwei Liu, Yun Liu, Gaofeng Yao, Yanhai Wu, Juanjuan Li, Feng Sun, Liang Sun & Longlong Sun
Pages: 4451-4460
Published online: 09 Oct 2023
AbstractforCorrelation Between Systemic Immune-Inflammation Index and Suicide Attempts in Children and Adolescents with First-Episode, Drug-Naïve Major Depressive Disorder During the COVID-19 Pandemic | Full Text | References | PDF (959.6 KB) | EPUB
  • 352 Views
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REVIEW

Review
The Activation of cGAS-STING in Acute Kidney Injury
Chuanchuan Sun, Heng Shi, Xinhai Zhao, Yu-Ling Chang, Xianghong Wang, Shiping Zhu & Shengyun Sun
Pages: 4461-4470
Published online: 10 Oct 2023
AbstractforThe Activation of cGAS-STING in Acute Kidney Injury | Full Text | References | PDF (2.4 MB) | EPUB
  • 139 Views
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Review
The Role of Caspase-11 and Pyroptosis in the Regulation of Inflammation in Peri-Implantitis
Pengcheng Jiao, Zuntai Li, Birong Li & Xingyuan Jiao
Pages: 4471-4479
Published online: 10 Oct 2023
AbstractforThe Role of Caspase-11 and Pyroptosis in the Regulation of Inflammation in Peri-Implantitis | Full Text | References | PDF (2.8 MB) | EPUB
  • 114 Views
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ORIGINAL RESEARCH

Article
Potential Role and Prognostic Value of Interleukin-15 for Mortality Among Elderly Patients with Sepsis
Jingjing Zhao, Ye Zhang, Junyu Wang, Bing Wei & Yugeng Liu
Pages: 4481-4488
Published online: 11 Oct 2023
AbstractforPotential Role and Prognostic Value of Interleukin-15 for Mortality Among Elderly Patients with Sepsis | Full Text | References | PDF (716.7 KB) | EPUB
  • 100 Views
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Article
Identification of Plasma Inflammatory Markers of Adolescent Depression Using the Olink Proteomics Platform
Ling Yang, Maolin Cao, Jing Tian, Peijin Cui, Ling Ai, Xue Li, Hua Li, Menghan Gao, Liang Fang, Libo Zhao, Fang Gong & Chanjuan Zhou
Pages: 4489-4501
Published online: 11 Oct 2023
AbstractforIdentification of Plasma Inflammatory Markers of Adolescent Depression Using the Olink Proteomics Platform | Full Text | References | PDF (6.7 MB) | EPUB
  • 516 Views
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REVIEW

Review
The Role of Inflammation in Cholestatic Liver Injury
Jie Chen & Shujun Zhang
Pages: 4527-4540
Published online: 13 Oct 2023
AbstractforThe Role of Inflammation in Cholestatic Liver Injury | Full Text | References | PDF (1.5 MB) | EPUB
  • 174 Views
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Review
Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
Kaiyang Wang, Huhai Zhang, Lie Yuan, Xiaoli Li & Yongqing Cai
Pages: 4503-4526
Published online: 13 Oct 2023
AbstractforPotential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review | Full Text | References | PDF (6.6 MB) | EPUB
  • 303 Views
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ORIGINAL RESEARCH

Article
Electroacupuncture Pretreatment Attenuates Learning Memory Impairment Induced by Repeated Propofol Exposure and Modulates Hippocampal Synaptic Plasticity in Rats
Shunqin Fan, Xijun Wang, Ning Gao & Songli Wei
Pages: 4559-4573
Published online: 16 Oct 2023
AbstractforElectroacupuncture Pretreatment Attenuates Learning Memory Impairment Induced by Repeated Propofol Exposure and Modulates Hippocampal Synaptic Plasticity in Rats | Full Text | References | PDF (7.4 MB) | EPUB
  • 114 Views
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Article
Comparison of the Predicting Value of Neutrophil to high-Density Lipoprotein Cholesterol Ratio and Monocyte to high-Density Lipoprotein Cholesterol Ratio for in-Hospital Prognosis and Severe Coronary Artery Stenosis in Patients with ST-Segment Elevation Acute Myocardial Infarction Following Percutaneous Coronary Intervention: A Retrospective Study
Jiongchao Guo, Min Chen, Yu Hong, Yating Huang, Haiyan Zhang, Yuan Zhou, Bingfeng Zhou & Minmin Fu
Pages: 4541-4557
Published online: 16 Oct 2023
AbstractforComparison of the Predicting Value of Neutrophil to high-Density Lipoprotein Cholesterol Ratio and Monocyte to high-Density Lipoprotein Cholesterol Ratio for in-Hospital Prognosis and Severe Coronary Artery Stenosis in Patients with ST-Segment Elevation Acute Myocardial Infarction Following Percutaneous Coronary Intervention: A Retrospective Study | Full Text | References | PDF (6.6 MB) | EPUB
  • 194 Views
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REVIEW

Review
The Chains of Ferroptosis Interact in the Whole Progression of Atherosclerosis
Xueqi Wan, Huan Zhang, Jinfan Tian, Peng Hao, Libo Liu, Yuquan Zhou, Jing Zhang, Xiantao Song & Changjiang Ge
Pages: 4575-4592
Published online: 16 Oct 2023
AbstractforThe Chains of Ferroptosis Interact in the Whole Progression of Atherosclerosis | Full Text | References | PDF (5.3 MB) | EPUB
  • 189 Views
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Review
The Independent Value of Neutrophil to Lymphocyte Ratio in Gouty Arthritis: A Narrative Review
Yiming Chen, Jian Liu, Yang Li, Chengzhi Cong, Yuedi Hu, Xianheng Zhang & Qi Han
Pages: 4593-4601
Published online: 16 Oct 2023
AbstractforThe Independent Value of Neutrophil to Lymphocyte Ratio in Gouty Arthritis: A Narrative Review | Full Text | References | PDF (462.5 KB) | EPUB
  • 201 Views
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ORIGINAL RESEARCH

Article
Serum Exosomal Long Noncoding RNA Growth Arrest-Specific 5 Predicts 3-Month Mortality in Acute-on-Chronic Hepatitis B Liver Failure
Cheng-Xi Sun, Li-Yan Han, Kai Wang & Shuai Gao
Pages: 4603-4616
Published online: 17 Oct 2023
AbstractforSerum Exosomal Long Noncoding RNA Growth Arrest-Specific 5 Predicts 3-Month Mortality in Acute-on-Chronic Hepatitis B Liver Failure | Full Text | References | PDF (9.4 MB) | EPUB
  • 98 Views
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Article
Identification of Targets for Subsequent Treatment of Crohn’s Disease Patients After Failure of Anti-TNF Therapy
Yao Yao, Liu Yang, Zhe Zhang, Binbin Wang, Baisui Feng & Zhanju Liu
Pages: 4617-4631
Published online: 17 Oct 2023
AbstractforIdentification of Targets for Subsequent Treatment of Crohn’s Disease Patients After Failure of Anti-TNF Therapy | Full Text | References | PDF (8.9 MB) | EPUB
  • 143 Views
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REVIEW

Review
Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis
Maheswari Muruganandam, Angie Ariza-Hutchinson, Rosemina A Patel & Wilmer L Sibbitt Jr
Pages: 4633-4660
Published online: 17 Oct 2023
AbstractforBiomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis | Full Text | References | PDF (1.4 MB) | EPUB
  • 490 Views
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ORIGINAL RESEARCH

Article
Immune-Related Genes in the Pathogenesis of Atherosclerosis: Based on Sex Differences
Peng Zhang, Hui Lin, Yan Guo, Fang Peng & Liping Meng
Pages: 4713-4724
Published online: 18 Oct 2023
AbstractforImmune-Related Genes in the Pathogenesis of Atherosclerosis: Based on Sex Differences | Full Text | References | PDF (8.3 MB) | EPUB
  • 151 Views
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Article
Identification of Key Immune-Related Genes in the Treatment of Heart Failure After Myocardial Infarction with Empagliflozin Based on RNA-Seq
Pei Zhang, Tian-Yu Wang, Zi-Yue Luo, Jun-Can Ding, Qiang Yang & Peng-Fei Hu
Pages: 4679-4696
Published online: 18 Oct 2023
AbstractforIdentification of Key Immune-Related Genes in the Treatment of Heart Failure After Myocardial Infarction with Empagliflozin Based on RNA-Seq | Full Text | References | PDF (14.7 MB) | EPUB
  • 130 Views
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Article
Prognostic Model and Tumor Immune Microenvironment Analysis of Complement-Related Genes in Gastric Cancer
Xianhua Gu, Honghong Shen, Guangzheng Zhu, Xinwei Li, Yue Zhang, Rong Zhang, Fang Su & Zishu Wang
Pages: 4697-4711
Published online: 18 Oct 2023
AbstractforPrognostic Model and Tumor Immune Microenvironment Analysis of Complement-Related Genes in Gastric Cancer | Full Text | References | PDF (16.6 MB) | EPUB
  • 132 Views
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REVIEW

Review
Targeting Ferroptosis in Bone-Related Diseases: Facts and Perspectives
Haoran Chen, Zhongyu Han, Yi Wang, Junyan Su, Yumeng Lin, Xuhua Cheng, Wen Liu, Jingyu He, Yiyue Fan, Liuyan Chen & Houdong Zuo
Pages: 4661-4677
Published online: 18 Oct 2023
AbstractforTargeting Ferroptosis in Bone-Related Diseases: Facts and Perspectives | Full Text | References | PDF (4.2 MB) | EPUB
  • 225 Views
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ORIGINAL RESEARCH

Article
Integration of RNA-Seq and Machine Learning Identifies Hub Genes for Empagliflozin Benefitable Heart Failure with Reduced Ejection Fraction
Qiang Yang, Jing Gao, Tian-Yu Wang, Jun-Can Ding & Peng-Fei Hu
Pages: 4733-4749
Published online: 18 Oct 2023
AbstractforIntegration of RNA-Seq and Machine Learning Identifies Hub Genes for Empagliflozin Benefitable Heart Failure with Reduced Ejection Fraction | Full Text | References | PDF (12.6 MB) | EPUB
  • 169 Views
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Article
Combination of NK and Other Immune Markers at Early Phase Stratify the Risk of Sepsis Patients: A Retrospective Study
Zihan Hu, Danjiang Dong, Fei Peng, Xing Zhou, Qin Sun, Hui Chen, Wei Chang, Qin Gu, Jianfeng Xie & Yi Yang
Pages: 4725-4732
Published online: 18 Oct 2023
AbstractforCombination of NK and Other Immune Markers at Early Phase Stratify the Risk of Sepsis Patients: A Retrospective Study | Full Text | References | PDF (1.4 MB) | EPUB
  • 91 Views
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Article
Chonggu Granules Improve Cartilage Matrix Metabolism in Knee Osteoarthritis via the miR-148a-3p/Wnt/β-Catenin Pathway
Lili Cheng, Chuanbing Huang, Ming Li, Shuangshuang Shang, Junjie Chen & Zhongfu Tang
Pages: 4751-4762
Published online: 20 Oct 2023
AbstractforChonggu Granules Improve Cartilage Matrix Metabolism in Knee Osteoarthritis via the miR-148a-3p/Wnt/β-Catenin Pathway | Full Text | References | PDF (4.9 MB) | EPUB
  • 136 Views
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REVIEW

Review
Mesenchymal Stem Cell Transplantation: Neuroprotection and Nerve Regeneration After Spinal Cord Injury
Si-Yu Chen, Rui-Lin Yang, Xiang-Chong Wu, De-Zhi Zhao, Sheng-Ping Fu, Feng-Qin Lin, Lin-Yan Li, Li-Mei Yu, Qian Zhang & Tao Zhang
Pages: 4763-4776
Published online: 20 Oct 2023
AbstractforMesenchymal Stem Cell Transplantation: Neuroprotection and Nerve Regeneration After Spinal Cord Injury | Full Text | References | PDF (3.1 MB) | EPUB
  • 215 Views
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Article
Sinomenine Ameliorates IL-1β-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-κB Signaling Pathways
Gongbiao Lu, Cunxin Zhang, Kang Li, Kai Gao, Maoqing Fu, Chaoliang Lyu & Zhengxue Quan
Pages: 4777-4791
Published online: 20 Oct 2023
AbstractforSinomenine Ameliorates IL-1β-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-κB Signaling Pathways | Full Text | References | PDF (9.6 MB) | EPUB
  • 121 Views
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Article
NLR48 is Better Than CRP, and mCTSI, and Similar to BISAP and SOFA Scores for Mortality Prediction in Acute Pancreatitis: A Comparison of 6 Scores
Sergiu Marian Cazacu, Mircea Parscoveanu, Dan Cartu, Emil Moraru, Ion Rogoveanu, Bogdan Silviu Ungureanu, Sevastita Iordache, Dan Nicolae Florescu, Vlad Florin Iovanescu & Manuela Iuliana Dragomir
Pages: 4793-4804
Published online: 20 Oct 2023
AbstractforNLR48 is Better Than CRP, and mCTSI, and Similar to BISAP and SOFA Scores for Mortality Prediction in Acute Pancreatitis: A Comparison of 6 Scores | Full Text | References | PDF (3.3 MB) | EPUB
  • 111 Views
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Article
Systemic Inflammation Response Index as a Predictor of Stroke Risk in Elderly Patients with Hypertension: A Cohort Study
Xintian Cai, Shuaiwei Song, Junli Hu, Lei Wang, Di Shen, Qing Zhu, Wenbo Yang, Qin Luo, Jing Hong & Nanfang Li
Pages: 4821-4832
Published online: 24 Oct 2023
AbstractforSystemic Inflammation Response Index as a Predictor of Stroke Risk in Elderly Patients with Hypertension: A Cohort Study | Full Text | References | PDF (4.5 MB) | EPUB
  • 205 Views
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Article
Creation of a Rat Takotsubo Syndrome Model and Utilization of Machine Learning Algorithms for Screening Diagnostic Biomarkers
Hongyu Huai, Junliang Li, Xiangjie Zhang, Qiang Xu & Huan Lan
Pages: 4833-4843
Published online: 24 Oct 2023
AbstractforCreation of a Rat Takotsubo Syndrome Model and Utilization of Machine Learning Algorithms for Screening Diagnostic Biomarkers | Full Text | References | PDF (6.6 MB) | EPUB
  • 106 Views
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Article
Aerobic Exercise Ameliorates Liver Injury in Db/Db Mice by Attenuating Oxidative Stress, Apoptosis and Inflammation Through the Nrf2 and JAK2/STAT3 Signalling Pathways
Meiyan Sun, Xiaoyong Zhao, Xingyue Li, Chunling Wang, Lili Lin, Kaifang Wang, Yingui Sun, Wei Ye, Haiyan Li, Ye Zhang & Chaolu Huang
Pages: 4805-4819
Published online: 24 Oct 2023
AbstractforAerobic Exercise Ameliorates Liver Injury in Db/Db Mice by Attenuating Oxidative Stress, Apoptosis and Inflammation Through the Nrf2 and JAK2/STAT3 Signalling Pathways | Full Text | References | PDF (10.4 MB) | EPUB
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Article
Soluble TAM Receptor Tyrosine Kinases Correlate with Disease Severity and Predict the Early Responsiveness of Sublingual Immunotherapy in Allergic Rhinitis
Yandan Zhou, Zhili Feng, Jie Wen, Chi Yang & Qiancheng Jing
Pages: 4845-4855
Published online: 25 Oct 2023
AbstractforSoluble TAM Receptor Tyrosine Kinases Correlate with Disease Severity and Predict the Early Responsiveness of Sublingual Immunotherapy in Allergic Rhinitis | Full Text | References | PDF (6.2 MB) | EPUB
  • 95 Views
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Article
Association Between Neutrophil-to-Lymphocyte Ratio and Benign Prostatic Hyperplasia: Results from the TCLSIH Cohort Study
Yanqi Song, Yeqing Gu, Honglei Guo, Honghao Yang, Xuena Wang, Hongmei Wu, Aidi Wang, Haijin Wang, Quan Zhang, Qing Zhang, Li Liu, Ge Meng, Baoshan Liu & Kaijun Niu
Pages: 4857-4866
Published online: 25 Oct 2023
AbstractforAssociation Between Neutrophil-to-Lymphocyte Ratio and Benign Prostatic Hyperplasia: Results from the TCLSIH Cohort Study | Full Text | References | PDF (498.7 KB) | EPUB
  • 132 Views
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Article
Antrodia cinnamomea May Interfere with the Interaction Between ACE2 and SARS-CoV-2 Spike Protein in vitro and Reduces Lung Inflammation in a Hamster Model of COVID-19
Lan-Hui Li, Hsiao-Wen Chiu, Wei-Ting Wong, Ko-Chieh Huang, Tzu-Wen Lin, Shui-Tein Chen & Kuo-Feng Hua
Pages: 4867-4884
Published online: 26 Oct 2023
AbstractforAntrodia cinnamomea May Interfere with the Interaction Between ACE2 and SARS-CoV-2 Spike Protein in vitro and Reduces Lung Inflammation in a Hamster Model of COVID-19 | Full Text | References | PDF (9 MB) | EPUB
  • 198 Views
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Article
Down Regulation of EGF and AZGP1 Were Associated with Clinical Characteristics in Chronic Rhinosinusitis with Nasal Polyps: An Observation Study
Peng Jin, Qinqin Zhang, Yiran Zang, Li Zhao, Hongyang Zhang, Kena Yu, Xu Liang, Xiaoxue Zi & Li Shi
Pages: 4885-4898
Published online: 28 Oct 2023
AbstractforDown Regulation of EGF and AZGP1 Were Associated with Clinical Characteristics in Chronic Rhinosinusitis with Nasal Polyps: An Observation Study | Full Text | References | PDF (10.2 MB) | EPUB
  • 121 Views
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Article
Effect of Hyperbaric Oxygen Intervention on Oxidative Stress and Expression of Nerve Growth Factor in Patients with Craniocerebral Injury
Bingyan Ren, Hanbin Ye, Wenyuan Shan, Xuelei Tao & Zi Ye
Pages: 4925-4932
Published online: 30 Oct 2023
AbstractforEffect of Hyperbaric Oxygen Intervention on Oxidative Stress and Expression of Nerve Growth Factor in Patients with Craniocerebral Injury | Full Text | References | PDF (3.6 MB) | EPUB
  • 121 Views
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Article
Fenugreek Seed Ethanolic Extract Improves Alveolar Bone Parameters by Attenuating Inflammation in Ovariectomized Rats
Ester Handayani Lodra, Muhammad Chair Effendi, Nur Pematasari & Respati Suryanto Dradjat
Pages: 4933-4940
Published online: 30 Oct 2023
AbstractforFenugreek Seed Ethanolic Extract Improves Alveolar Bone Parameters by Attenuating Inflammation in Ovariectomized Rats | Full Text | References | PDF (4.3 MB) | EPUB
  • 249 Views
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Article
CXCL10 May Be Responsible for Susceptibility to Pulmonary Embolism in COVID-19 Patients
Yingli Liu, Dan Si, Pingping Bai, Li Zhu, Lili Zhang, Qi Chen & Yong Qi
Pages: 4913-4924
Published online: 31 Oct 2023
AbstractforCXCL10 May Be Responsible for Susceptibility to Pulmonary Embolism in COVID-19 Patients | Full Text | References | PDF (6.9 MB) | EPUB
  • 124 Views
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Article
Identification of Ferroptosis-Related Genes in Heart Failure Induced by Transverse Aortic Constriction
Jian Jun Gu, Tian Jian Du, Li Na Zhang, Jing Zhou, Xiang Gu & Ye Zhu
Pages: 4899-4912
Published online: 31 Oct 2023
AbstractforIdentification of Ferroptosis-Related Genes in Heart Failure Induced by Transverse Aortic Constriction | Full Text | References | PDF (11.6 MB) | EPUB
  • 133 Views
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Article
Identification of Cell-Cell Communications by Single-Cell RNA Sequencing in End Stage Renal Disease Provides New Insights into Immune Cell Heterogeneity
Ruijing Zhang, Xinyan Liu, Yuehong Ma, Lijuan Cheng, Yi Ren & Rongshan Li
Pages: 4977-5000
Published online: 31 Oct 2023
AbstractforIdentification of Cell-Cell Communications by Single-Cell RNA Sequencing in End Stage Renal Disease Provides New Insights into Immune Cell Heterogeneity | Full Text | References | PDF (14.8 MB) | EPUB
  • 256 Views
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Article
Analysis of Human microRNA Expression Profiling During Diquat-Induced Renal Proximal Tubular Epithelial Cell Injury
Yang Chen, Hui-Yi Li, Jian-Shu Liu, Dao-long Jiang, Hao-nan Zheng & Xue-Song Dong
Pages: 4953-4965
Published online: 31 Oct 2023
AbstractforAnalysis of Human microRNA Expression Profiling During Diquat-Induced Renal Proximal Tubular Epithelial Cell Injury | Full Text | References | PDF (5.8 MB) | EPUB
  • 117 Views
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Article
Inflammation and Coagulation are Two Interconnected Pathophysiological Pathways in Atrial Fibrillation Pathogenesis
Lusine Hazarapetyan, Parounak H Zelveian & Svetlana Grigoryan
Pages: 4967-4975
Published online: 31 Oct 2023
AbstractforInflammation and Coagulation are Two Interconnected Pathophysiological Pathways in Atrial Fibrillation Pathogenesis | Full Text | References | PDF (406.1 KB) | EPUB
  • 115 Views
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Article
Clinical Significance of Mean Platelet Volume Combined with Neutrophil–Lymphocyte Ratio in Predicting the Therapeutic Effect of Splanchnic Neurolysis
Junzhu Dai, Yuxiang Han, Tianyi Fang, Hongxue Shao, Lei Teng & Huichao Zou
Pages: 5027-5037
Published online: 31 Oct 2023
AbstractforClinical Significance of Mean Platelet Volume Combined with Neutrophil–Lymphocyte Ratio in Predicting the Therapeutic Effect of Splanchnic Neurolysis | Full Text | References | PDF (3.6 MB) | EPUB
  • 114 Views
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Article
The m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome
Haishi Zheng, Yirixiati Aihaiti, Yongsong Cai, Qiling Yuan, Mingyi Yang, Zheng Li, Ke Xu & Peng Xu
Pages: 5001-5025
Published online: 01 Nov 2023
AbstractforThe m6A/m1A/m5C-Related Methylation Modification Patterns and Immune Landscapes in Rheumatoid Arthritis and Osteoarthritis Revealed by Microarray and Single-Cell Transcriptome | Full Text | References | PDF (24.2 MB) | EPUB
  • 343 Views
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Article
Potential Proallergenic Activity of Phytopathogenic Erysiphe palczewskii and Erysiphe convolvuli in in vitro Studies
Monika Sztandera-Tymoczek, Sylwia Wdowiak-Wróbel, Urszula Świderska, Marta Palusińska-Szysz & Agnieszka Szuster-Ciesielska
Pages: 5039-5060
Published online: 01 Nov 2023
AbstractforPotential Proallergenic Activity of Phytopathogenic Erysiphe palczewskii and Erysiphe convolvuli in in vitro Studies | Full Text | References | PDF (11.5 MB) | EPUB
  • 130 Views
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REVIEW

Review
Molecular Mechanisms of Ferroptosis and Their Involvement in Acute Kidney Injury
Jie Liu, Xiaoxia Han, Jia Zhou & Yufang Leng
Pages: 4941-4951
Published online: 01 Nov 2023
AbstractforMolecular Mechanisms of Ferroptosis and Their Involvement in Acute Kidney Injury | Full Text | References | PDF (3 MB) | EPUB
  • 125 Views
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CASE REPORT

Case Report
Toxic Epidermal Necrolysis and Stevens - Johnson Syndrome Following Sintilimab Administration in a Non-Small Cell Lung Cancer Patient: A Case Report
Ziyu Jiang, Xiaoli Chen, Zhaoshen Sun, Xiaowei Shen, Yaju Huang & Jingbing Liu
Pages: 5061-5067
Published online: 02 Nov 2023
AbstractforToxic Epidermal Necrolysis and Stevens - Johnson Syndrome Following Sintilimab Administration in a Non-Small Cell Lung Cancer Patient: A Case Report | Full Text | References | PDF (892.2 KB) | EPUB
  • 116 Views
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ORIGINAL RESEARCH

Article
The Systemic Immune Inflammatory Response Index Can Predict the Clinical Prognosis of Patients with Initially Diagnosed Coronary Artery Disease
Yuqing Li, Geng Bai, Yi Gao, Ziqiang Guo, Xiaolin Chen, Tong Liu & Guangping Li
Pages: 5069-5082
Published online: 03 Nov 2023
AbstractforThe Systemic Immune Inflammatory Response Index Can Predict the Clinical Prognosis of Patients with Initially Diagnosed Coronary Artery Disease | Full Text | References | PDF (3.7 MB) | EPUB
  • 271 Views
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Article
Clinical Value of Laboratory Biomarkers for the Diagnosis and Early Identification of Culture-Positive Sepsis in Neonates
Chumei Huang, Jiahui Chen, Xiaoxia Zhan, Laisheng Li, Shu An, Guijun Cai & Nan Yu
Pages: 5111-5124
Published online: 06 Nov 2023
AbstractforClinical Value of Laboratory Biomarkers for the Diagnosis and Early Identification of Culture-Positive Sepsis in Neonates | Full Text | References | PDF (1.8 MB) | EPUB
  • 201 Views
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REVIEW

Review
Primary Angiitis of the Central Nervous System in Adults: A Comprehensive Review of 76 Biopsy-Proven Case Reports
Ping Lu, Lingyun Cui & Xinghu Zhang
Pages: 5083-5094
Published online: 06 Nov 2023
AbstractforPrimary Angiitis of the Central Nervous System in Adults: A Comprehensive Review of 76 Biopsy-Proven Case Reports | Full Text | References | PDF (2.7 MB) | EPUB
  • 133 Views
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ORIGINAL RESEARCH

Article
LPA2 Alleviates Septic Acute Lung Injury via Protective Endothelial Barrier Function Through Activation of PLC-PKC-FAK
Ruifeng Bai, Jianqiu Pei, Shengqiang Pei, Xiangfeng Cong, Jerold Chun, Fang Wang & Xi Chen
Pages: 5095-5109
Published online: 08 Nov 2023
AbstractforLPA2 Alleviates Septic Acute Lung Injury via Protective Endothelial Barrier Function Through Activation of PLC-PKC-FAK | Full Text | References | PDF (13.4 MB) | EPUB
  • 122 Views
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Article
Transcriptomics Analysis Revealed Key Genes Associated with Macrophage Autophagolysosome in Male ApoE−/− Mice Aortic Atherosclerosis
Meirong Zhu, Tongyu Jin, Ding Wu, Shanchao Zhang & Aihua Wang
Pages: 5125-5144
Published online: 08 Nov 2023
AbstractforTranscriptomics Analysis Revealed Key Genes Associated with Macrophage Autophagolysosome in Male ApoE−/− Mice Aortic Atherosclerosis | Full Text | References | PDF (16.3 MB) | EPUB
  • 143 Views
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Article
Prognostic Value of Body Composition and Systemic Inflammatory Markers in Patients with Locally Advanced Cervical Cancer Following Chemoradiotherapy
Hui Guo, Shuai Feng, Zhiqiang Li, Yueju Yin, Xueying Lin, Lingqin Yuan, Xiugui Sheng & Dapeng Li
Pages: 5145-5156
Published online: 09 Nov 2023
AbstractforPrognostic Value of Body Composition and Systemic Inflammatory Markers in Patients with Locally Advanced Cervical Cancer Following Chemoradiotherapy | Full Text | References | PDF (2.4 MB) | EPUB
  • 135 Views
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Article
Kawasaki Disease Associated Acute Abdomen: Most Require No Surgery
Xiang She, Jia Chen, Yu-Neng Zhou, Jun Guo, Feng-Hua Zhao & Cong Yi
Pages: 5157-5162
Published online: 09 Nov 2023
AbstractforKawasaki Disease Associated Acute Abdomen: Most Require No Surgery | Full Text | References | PDF (363 KB) | EPUB
  • 100 Views
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CASE REPORT

Case Report
Myeloid/Lymphoid Neoplasms with ETV6::PDGFRB Fusion Gene: A Rare Case of Poor Response to Imatinib and Possible Transformation Mechanisms from Myeloid Neoplasms of Bone Marrow to T-Cell Lymphoblastic Lymphoma Invasion in Lymph Nodes
Yang Gou, Yongjie Tang, Shuiqing Liu, Siyu Cheng, Xiaojuan Deng, Qin Wen, Yimei Feng, Xiangui Peng, Ping Wang & Xi Zhang
Pages: 5163-5170
Published online: 10 Nov 2023
AbstractforMyeloid/Lymphoid Neoplasms with ETV6::PDGFRB Fusion Gene: A Rare Case of Poor Response to Imatinib and Possible Transformation Mechanisms from Myeloid Neoplasms of Bone Marrow to T-Cell Lymphoblastic Lymphoma Invasion in Lymph Nodes | Full Text | References | PDF (5 MB) | EPUB
  • 120 Views
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ORIGINAL RESEARCH

Article
Single-Cell RNA-Sequencing Analysis of Colonic Lamina Propria Immune Cells Reveals the Key Immune Cell-Related Genes of Ulcerative Colitis
Run Hua, Gangjie Qiao, Guoshan Chen, Zhaonan Sun, Haowen Jia, Peiyuan Li, Baotong Zhang & Feng Qi
Pages: 5171-5188
Published online: 10 Nov 2023
AbstractforSingle-Cell RNA-Sequencing Analysis of Colonic Lamina Propria Immune Cells Reveals the Key Immune Cell-Related Genes of Ulcerative Colitis | Full Text | References | PDF (16.1 MB) | EPUB
  • 211 Views
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Article
The Systemic Inflammation Index Predicts Poor Clinical Prognosis in Patients with Initially Diagnosed Acute Coronary Syndrome Undergoing Primary Coronary Angiography
Yi Gao, Yuqing Li, Xiaolin Chen, Chen Wu, Ziqiang Guo, Geng Bai, Tong Liu & Guangping Li
Pages: 5205-5219
Published online: 12 Nov 2023
AbstractforThe Systemic Inflammation Index Predicts Poor Clinical Prognosis in Patients with Initially Diagnosed Acute Coronary Syndrome Undergoing Primary Coronary Angiography | Full Text | References | PDF (4.3 MB) | EPUB
  • 176 Views
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CLINICAL TRIAL REPORT

Peripheral Blood Inflammatory Cytokine Factors Expressions are Associated with Response to Acupuncture Therapy in Postpartum Depression Patients
Yu-Qin Xu, YanHua Gou, Jin-Jun Yuan, Yan-Xian Zhu, Xiao-Ming Ma, Chen Chen, Xing-Xian Huang, Zhuo-Xin Yang & Yu-Mei Zhou
Pages: 5189-5203
Published online: 12 Nov 2023
AbstractforPeripheral Blood Inflammatory Cytokine Factors Expressions are Associated with Response to Acupuncture Therapy in Postpartum Depression Patients | Full Text | References | PDF (3.8 MB) | EPUB
  • 180 Views
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ORIGINAL RESEARCH

Article
A Nomogram Model for Post-Intubation Hypotension in Patients with Severe Pneumonia in the Emergency Department
Pan Pan, Tao Cheng, Tianyong Han & Yu Cao
Pages: 5221-5233
Published online: 12 Nov 2023
AbstractforA Nomogram Model for Post-Intubation Hypotension in Patients with Severe Pneumonia in the Emergency Department | Full Text | References | PDF (5.8 MB) | EPUB
  • 105 Views
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Article
Circulating Inflammatory Factor Levels in the Early Phase of COVID-19 are Associated with the Progression of Respiratory Failure: A Single-Center Retrospective Study
Xiaoli Xiang, Zhicheng Zhang, Ying Liu, Wenxuan Xu, Ju Gong, Sheng Yu, Lan Zhang & Tingwang Jiang
Pages: 5249-5260
Published online: 13 Nov 2023
AbstractforCirculating Inflammatory Factor Levels in the Early Phase of COVID-19 are Associated with the Progression of Respiratory Failure: A Single-Center Retrospective Study | Full Text | References | PDF (1,018.3 KB) | EPUB
  • 108 Views
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Article
Disturbance of Adaptive Immunity System Was Accompanied by a Decrease in Plasma Short-Chain Fatty Acid for Patients Hospitalized During SARS-CoV-2 Infection After COVID-19 Vaccination
Zhaojun Liang, Nan Wang, Chunxue Fan, Lili Shang, Yaping Zhang, Chong Gao & Jing Luo
Pages: 5261-5272
Published online: 13 Nov 2023
AbstractforDisturbance of Adaptive Immunity System Was Accompanied by a Decrease in Plasma Short-Chain Fatty Acid for Patients Hospitalized During SARS-CoV-2 Infection After COVID-19 Vaccination | Full Text | References | PDF (4.5 MB) | EPUB
  • 122 Views
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Article
Leptin Induces MMP-1 Expression Through the RhoA/ERK1/2/NF-κB Axis in Human Intervertebral Disc Cartilage Endplate-Derived Stem Cells
Kuo-Feng Hua, Lan-Hui Li, Hsin-Chiao Yu, Wei-Ting Wong & Hsien-Ta Hsu
Pages: 5235-5248
Published online: 14 Nov 2023
AbstractforLeptin Induces MMP-1 Expression Through the RhoA/ERK1/2/NF-κB Axis in Human Intervertebral Disc Cartilage Endplate-Derived Stem Cells | Full Text | References | PDF (5.5 MB) | EPUB
  • 167 Views
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REVIEW

Review
Chronic Inflammatory and Immune Microenvironment Promote Hepatocellular Carcinoma Evolution
Shimin Chen, Long Zhang, Yukun Chen, Xuzhi Zhang & Yi Ma
Pages: 5287-5298
Published online: 14 Nov 2023
AbstractforChronic Inflammatory and Immune Microenvironment Promote Hepatocellular Carcinoma Evolution | Full Text | References | PDF (3.2 MB) | EPUB
  • 187 Views
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ORIGINAL RESEARCH

Article
Predictive Effect of System Inflammation Response Index for Progression of Chronic Kidney Disease in Non-Dialyzing Patient
Leile Tang, Ying Deng, Jiahui Lai, Xinghua Guo, Peijia Liu, Shaomin Li & Xun Liu
Pages: 5273-5285
Published online: 15 Nov 2023
AbstractforPredictive Effect of System Inflammation Response Index for Progression of Chronic Kidney Disease in Non-Dialyzing Patient | Full Text | References | PDF (2.8 MB) | EPUB
  • 153 Views
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Article
Fusing WGCNA and Machine Learning for Immune-Related Gene Prognostic Index in Lung Adenocarcinoma: Precision Prognosis, Tumor Microenvironment Profiling, and Biomarker Discovery
Jiaming He, Tiankuo Luan, Gang Zhao & Yingxue Yang
Pages: 5309-5326
Published online: 15 Nov 2023
AbstractforFusing WGCNA and Machine Learning for Immune-Related Gene Prognostic Index in Lung Adenocarcinoma: Precision Prognosis, Tumor Microenvironment Profiling, and Biomarker Discovery | Full Text | References | PDF (11 MB) | EPUB
  • 206 Views
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Article
Decreased Peripheral Blood Lymphocyte Count Predicts Poor Treatment Response in Peritoneal Dialysis-Associated Peritonitis
YuJian He, XiaoYan Huang, Jingwen Zhang, Jinlan Liao, Huie Huang, Yan He, Min Gao, Yumei Liao & Zibo Xiong
Pages: 5327-5338
Published online: 15 Nov 2023
AbstractforDecreased Peripheral Blood Lymphocyte Count Predicts Poor Treatment Response in Peritoneal Dialysis-Associated Peritonitis | Full Text | References | PDF (3.6 MB) | EPUB
  • 89 Views
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Article
Predictive Value of Glycemic Variability and HDL-C for Secondary Persistent Inflammatory Immunosuppressed Catabolic Syndrome in Patients with Sepsis
Jiali Yao, Kun Chen, Hongjie Tong & Ruixin Liu
Pages: 5299-5307
Published online: 15 Nov 2023
AbstractforPredictive Value of Glycemic Variability and HDL-C for Secondary Persistent Inflammatory Immunosuppressed Catabolic Syndrome in Patients with Sepsis | Full Text | References | PDF (1.6 MB) | EPUB
  • 84 Views
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Article
Diagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus
Yu Liu, Enyi Zhu, Yan Lei, Ailing Luo, Yaping Yan, Mansi Cai, Shanshan Liu, Yan Huang, Hui Guan, Ming Zhong, Weinian Li, Lian Lin, Michael Hultstöm, Enyin Lai, Zhihua Zheng, Xiaoping Liu & Chun Tang
Pages: 5367-5383
Published online: 16 Nov 2023
AbstractforDiagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus | Full Text | References | PDF (6.5 MB) | EPUB
  • 132 Views
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Article
lncRNA TPRG1-AS1 Screened the Onset of Acute Coronary Syndromes and Predicted Severity and the Occurrence of MACE During Patients’ Hospitalization
Fan Zhang, Wei Li, Yingying Zhang, Dong Wang, Jing Li, Chengpeng Li & Liqun He
Pages: 5385-5391
Published online: 16 Nov 2023
AbstractforlncRNA TPRG1-AS1 Screened the Onset of Acute Coronary Syndromes and Predicted Severity and the Occurrence of MACE During Patients’ Hospitalization | Full Text | References | PDF (2.6 MB) | EPUB
  • 89 Views
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Article
Anti-Inflammatory and Therapeutic Effects of a Novel Small-Molecule Inhibitor of Inflammation in a Male C57BL/6J Mouse Model of Obesity-Induced NAFLD/MAFLD
Kelly D McCall, Debra Walter, Ashley Patton, Jean R Thuma, Maria C Courreges, Grzegorz Palczewski, Douglas J Goetz, Stephen Bergmeier & Frank L Schwartz
Pages: 5339-5366
Published online: 17 Nov 2023
AbstractforAnti-Inflammatory and Therapeutic Effects of a Novel Small-Molecule Inhibitor of Inflammation in a Male C57BL/6J Mouse Model of Obesity-Induced NAFLD/MAFLD | Full Text | References | PDF (15 MB) | EPUB
  • 304 Views
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Article
U-Shaped Association Between Monocyte-Lymphocyte Ratio and Risk of Cardiac Conduction Block
Man Li, Xintao Li, Hongwei Gao, Peng Li, Li Zhang, Xiaoling Zhang, Peipei Liu, Xuemei Yang, Lili Wu, Jiangwei Zeng, Shouling Wu & Lixia Sun
Pages: 5393-5402
Published online: 17 Nov 2023
AbstractforU-Shaped Association Between Monocyte-Lymphocyte Ratio and Risk of Cardiac Conduction Block | Full Text | References | PDF (3 MB) | EPUB
  • 74 Views
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Article
Discordance Between Neutrophil to Lymphocyte Ratio and High Sensitivity C-Reactive Protein to Predict Clinical Events in Patients with Stable Coronary Artery Disease: A Large-Scale Cohort Study
Jining He, Chenxi Song, Rui Zhang, Sheng Yuan, Jianjun Li & Kefei Dou
Pages: 5439-5450
Published online: 20 Nov 2023
AbstractforDiscordance Between Neutrophil to Lymphocyte Ratio and High Sensitivity C-Reactive Protein to Predict Clinical Events in Patients with Stable Coronary Artery Disease: A Large-Scale Cohort Study | Full Text | References | PDF (4.1 MB) | EPUB
  • 145 Views
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Article
Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity
Shamma Almuraikhy, Maha Sellami, Hadaia Saleh Al-Amri, Alexander Domling, Asmaa A Althani & Mohamed A Elrayess
Pages: 5427-5438
Published online: 20 Nov 2023
AbstractforImpact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity | Full Text | References | PDF (555.1 KB) | EPUB
  • 183 Views
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Article
Sarcoplasmic Myxovirus Resistance Protein A: A Study of Expression in Idiopathic Inflammatory Myopathy
Jariya Waisayarat, Phumin Wongsuwan, Kiarttiyot Tuntiseranee, Phu Waisayarat, Charungthai Dejthevaporn, Chaiyos Khongkhatithum & Sirisucha Soponkanaporn
Pages: 5417-5426
Published online: 20 Nov 2023
AbstractforSarcoplasmic Myxovirus Resistance Protein A: A Study of Expression in Idiopathic Inflammatory Myopathy | Full Text | References | PDF (4.2 MB) | EPUB
  • 91 Views
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REVIEW

Review
AMPK Signalling Pathway: A Potential Strategy for the Treatment of Heart Failure with Chinese Medicine
Changxing Liu, Xinyi Guo, Yabin Zhou & He Wang
Pages: 5451-5464
Published online: 20 Nov 2023
AbstractforAMPK Signalling Pathway: A Potential Strategy for the Treatment of Heart Failure with Chinese Medicine | Full Text | References | PDF (1.5 MB) | EPUB
  • 132 Views
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CASE SERIES

Case Report
An Exploration of Anti-Inflammatory Therapy in Acute/Subacute Severe Cerebral Venous Thrombosis with Hereditary Protein C/S Deficiency: Case Series
Wensi Hao, Yaqin Gu, Shuyuan Hu, Xunming Ji, Yuping Wang & Jiangang Duan
Pages: 5403-5415
Published online: 21 Nov 2023
AbstractforAn Exploration of Anti-Inflammatory Therapy in Acute/Subacute Severe Cerebral Venous Thrombosis with Hereditary Protein C/S Deficiency: Case Series | Full Text | References | PDF (3.2 MB) | EPUB
  • 90 Views
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ORIGINAL RESEARCH

Article
Gastrointestinal Fistulas in Necrotizing Pancreatitis Receiving a Step-Up Approach Incidence, Risk Factors, Outcomes and Treatment
Zheyu Liu, Huajing Ke, Yuwen Xiong, Hui Liu, Mengli Yue & Pi Liu
Pages: 5531-5543
Published online: 21 Nov 2023
AbstractforGastrointestinal Fistulas in Necrotizing Pancreatitis Receiving a Step-Up Approach Incidence, Risk Factors, Outcomes and Treatment | Full Text | References | PDF (1.6 MB) | EPUB
  • 115 Views
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Article
Cerebral Microstructural and Microvascular Changes in Non-Neuropsychiatric Systemic Lupus Erythematosus: A Study Using Diffusion Kurtosis Imaging and 3D Pseudo-Continuous Arterial Spin Labeling
Xiaojuan Wang, Lingling Huang, Wenbin Guo, Langlang Tang, Aiyu Wu, Peng Wu, Xiance Zhao, Qi Lin & Lian Yu
Pages: 5465-5475
Published online: 21 Nov 2023
AbstractforCerebral Microstructural and Microvascular Changes in Non-Neuropsychiatric Systemic Lupus Erythematosus: A Study Using Diffusion Kurtosis Imaging and 3D Pseudo-Continuous Arterial Spin Labeling | Full Text | References | PDF (3 MB) | EPUB
  • 95 Views
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Article
Silver Nanoparticles and Graphene Oxide Complex as an Anti-Inflammatory Biocompatible Liquid Nano-Dressing for Skin Infected with Staphylococcus aureus
Marlena Zielińska-Górska, Malwina Sosnowska-Ławnicka, Sławomir Jaworski, Agata Lange, Karolina Daniluk, Barbara Nasiłowska, Bartosz Bartosewicz, André Chwalibog & Ewa Sawosz
Pages: 5477-5493
Published online: 21 Nov 2023
AbstractforSilver Nanoparticles and Graphene Oxide Complex as an Anti-Inflammatory Biocompatible Liquid Nano-Dressing for Skin Infected with Staphylococcus aureus | Full Text | References | PDF (8.5 MB) | EPUB
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REVIEW

Review
Bariatric Surgery and Gut-Brain-Axis Driven Alterations in Cognition and Inflammation
Emma Custers, Ayla Franco & Amanda Johanne Kiliaan
Pages: 5495-5514
Published online: 21 Nov 2023
AbstractforBariatric Surgery and Gut-Brain-Axis Driven Alterations in Cognition and Inflammation | Full Text | References | PDF (2 MB) | EPUB
  • 218 Views
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ORIGINAL RESEARCH

Article
A Novel Prognostic Model Predicts Outcomes in Non-Metastatic Nasopharyngeal Carcinoma Based on Inflammation, Nutrition, and Coagulation Signature
Li-Zhi Chen, Han-Shu Li, Gao-Wei Han, Yong Su, Tian-Zhu Lu, Hong-Hui Xie, Xiao-Chang Gong, Jin-Gao Li & Yun Xiao
Pages: 5515-5529
Published online: 21 Nov 2023
AbstractforA Novel Prognostic Model Predicts Outcomes in Non-Metastatic Nasopharyngeal Carcinoma Based on Inflammation, Nutrition, and Coagulation Signature | Full Text | References | PDF (8.7 MB) | EPUB
  • 90 Views
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Article
Lysosome-Related Diagnostic Biomarkers for Pediatric Sepsis Integrated by Machine Learning
Yang Yang & Genhao Zhang
Pages: 5575-5583
Published online: 23 Nov 2023
AbstractforLysosome-Related Diagnostic Biomarkers for Pediatric Sepsis Integrated by Machine Learning | Full Text | References | PDF (5.7 MB) | EPUB
  • 90 Views
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Article
The Potential of a CT-Based Machine Learning Radiomics Analysis to Differentiate Brucella and Pyogenic Spondylitis
Parhat Yasin, Muradil Mardan, Dilxat Abliz, Tao Xu, Nuerbiyan Keyoumu, Abasi Aimaiti, Xiaoyu Cai, Weibin Sheng & Mardan Mamat
Pages: 5585-5600
Published online: 23 Nov 2023
AbstractforThe Potential of a CT-Based Machine Learning Radiomics Analysis to Differentiate Brucella and Pyogenic Spondylitis | Full Text | References | PDF (9.4 MB) | EPUB
  • 155 Views
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REVIEW

Review
The Role and Mechanism of Metformin in Inflammatory Diseases
Huan Lin, Haiyong Ao, Guanghua Guo & Mingzhuo Liu
Pages: 5545-5564
Published online: 23 Nov 2023
AbstractforThe Role and Mechanism of Metformin in Inflammatory Diseases | Full Text | References | PDF (2 MB) | EPUB
  • 291 Views
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ORIGINAL RESEARCH

Article
New Inflammatory Marker Associated with Disease Activity in Gouty Arthritis: The Systemic Inflammatory Response Index
Yi Jiang, Xin Tu, Xia Liao, Yixi He, Shunbing Wang, Quanbo Zhang & Yufeng Qing
Pages: 5565-5573
Published online: 23 Nov 2023
AbstractforNew Inflammatory Marker Associated with Disease Activity in Gouty Arthritis: The Systemic Inflammatory Response Index | Full Text | References | PDF (2.6 MB) | EPUB
  • 300 Views
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Article
The Nrf2 Pathway Alleviates Overloading Force-Induced TMJ Degeneration by Downregulating Oxidative Stress Reactions
Minglu Xu, Lingli Fang, Qin Xue, Xuyang Zhang & Yao He
Pages: 5601-5612
Published online: 26 Nov 2023
AbstractforThe Nrf2 Pathway Alleviates Overloading Force-Induced TMJ Degeneration by Downregulating Oxidative Stress Reactions | Full Text | References | PDF (8 MB) | EPUB
  • 106 Views
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Article
Periodic Mechanical Stress Inhibits the Development of Osteoarthritis via Regulating ATF3-Akt Axis
Yi Lou, Fanglong Song, Yifan Kang & Yaozeng Xu
Pages: 5613-5628
Published online: 27 Nov 2023
AbstractforPeriodic Mechanical Stress Inhibits the Development of Osteoarthritis via Regulating ATF3-Akt Axis | Full Text | References | PDF (11.5 MB) | EPUB
  • 141 Views
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Article
Neutrophil Extracellular Traps Aggravate Contrast-Induced Acute Kidney Injury by Damaging Glomeruli and Peritubular Capillaries
Heng Wang, Tingting Gao, Ruijing Zhang, Jie Hu, Siqi Gao, Yuwen Wang, Xiaotong Qi, Yun Zhou, Guoping Zheng & Honglin Dong
Pages: 5629-5646
Published online: 26 Feb 2024
AbstractforNeutrophil Extracellular Traps Aggravate Contrast-Induced Acute Kidney Injury by Damaging Glomeruli and Peritubular Capillaries | Full Text | References | PDF (15.3 MB) | EPUB
  • 48 Views
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Article
Establishment and Analysis of an Artificial Neural Network Model for Early Detection of Polycystic Ovary Syndrome Using Machine Learning Techniques
Yumi Wu, QiWei Xiao, ShouDong Wang, Huanfang Xu & YiGong Fang
Pages: 5667-5676
Published online: 28 Nov 2023
AbstractforEstablishment and Analysis of an Artificial Neural Network Model for Early Detection of Polycystic Ovary Syndrome Using Machine Learning Techniques | Full Text | References | PDF (5.6 MB) | EPUB
  • 180 Views
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Article
A Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments
Zheming Zhang, Haoda Yu, Qi Wang, Yu Ding, Ziteng Wang, Songyun Zhao & Tao Bian
Pages: 5647-5665
Published online: 28 Nov 2023
AbstractforA Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments | Full Text | References | PDF (12.9 MB) | EPUB
  • 185 Views
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Article
Identification of a Novel Target Implicated in Chronic Obstructive Sleep Apnea-Related Atrial Fibrillation by Integrative Analysis of Transcriptome and Proteome
Jun Shen, Junqing Liang, Manzeremu Rejiepu, Ping Yuan, Jie Xiang, Yankai Guo, Jiasuoer Xiaokereti, Ling Zhang & Baopeng Tang
Pages: 5677-5695
Published online: 29 Nov 2023
AbstractforIdentification of a Novel Target Implicated in Chronic Obstructive Sleep Apnea-Related Atrial Fibrillation by Integrative Analysis of Transcriptome and Proteome | Full Text | References | PDF (19.7 MB) | EPUB
  • 121 Views
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Article
Integrated DNA Methylation and Transcriptomics Analyses of Lacrimal Glands Identify the Potential Genes Implicated in the Development of Sjögren’s Syndrome-Related Dry Eye
Mei Sun, Yankai Wei, Chengyuan Zhang, Hong Nian, Bei Du & Ruihua Wei
Pages: 5697-5714
Published online: 29 Nov 2023
AbstractforIntegrated DNA Methylation and Transcriptomics Analyses of Lacrimal Glands Identify the Potential Genes Implicated in the Development of Sjögren’s Syndrome-Related Dry Eye | Full Text | References | PDF (13.1 MB) | EPUB
  • 136 Views
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Article
Rapamycin Exacerbates Staphylococcus aureus Pneumonia by Inhibiting mTOR-RPS6 in Macrophages
Fang-Yi Yu, Kua Zheng, Yin-Fang Wu, Shen-Wei Gao, Qing-Yu Weng, Chen Zhu, Yan-Ping Wu, Miao Li, Zhong-Nan Qin, Jia-Fei Lou, Zhi-Hua Chen, Song-Min Ying, Hua-Hao Shen & Wen Li
Pages: 5715-5728
Published online: 30 Nov 2023
AbstractforRapamycin Exacerbates Staphylococcus aureus Pneumonia by Inhibiting mTOR-RPS6 in Macrophages | Full Text | References | PDF (11.5 MB) | EPUB
  • 139 Views
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Article
Prognostic Value of Fibrinogen-to-Albumin Ratio in Coronary Three-Vessel Disease
Xinsheng Li, Zhongzhen Wang, Yifan Zhu, Haichen Lv, Xuchen Zhou, Hao Zhu, Jinqiu Liu & Lei Guo
Pages: 5767-5777
Published online: 01 Dec 2023
AbstractforPrognostic Value of Fibrinogen-to-Albumin Ratio in Coronary Three-Vessel Disease | Full Text | References | PDF (2 MB) | EPUB
  • 135 Views
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Article
Quercetin is a Potential Therapy for Rheumatoid Arthritis via Targeting Caspase-8 Through Ferroptosis and Pyroptosis
Qingcong Zheng, Du Wang, Rongjie Lin, Yuchao Chen, Zixing Xu & Weihong Xu
Pages: 5729-5754
Published online: 01 Dec 2023
AbstractforQuercetin is a Potential Therapy for Rheumatoid Arthritis via Targeting Caspase-8 Through Ferroptosis and Pyroptosis | Full Text | References | PDF (24 MB) | EPUB
  • 311 Views
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Article
Association of sTREM‐1 and Neutrophil-to-Lymphocyte Ratio as Prognostic Markers in COVID-19 Short- and Long-Term Mortality
Lyudmila Turgunova, Irina Mekhantseva, Lyudmila Akhmaltdinova, Mikhail Kostinov, Zhibek Zhumadilova & Anar Turmukhambetova
Pages: 5807-5817
Published online: 04 Dec 2023
AbstractforAssociation of sTREM‐1 and Neutrophil-to-Lymphocyte Ratio as Prognostic Markers in COVID-19 Short- and Long-Term Mortality | Full Text | References | PDF (1.3 MB) | EPUB
  • 117 Views
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Article
Cartilage Endplate-Derived Stem Cells for Regeneration of Intervertebral Disc Degeneration: An Analytic Study
Zhiwei Jia, Donghua Liu, Xingxuan Li, Tianlin Wen & Wei Li
Pages: 5791-5806
Published online: 04 Dec 2023
AbstractforCartilage Endplate-Derived Stem Cells for Regeneration of Intervertebral Disc Degeneration: An Analytic Study | Full Text | References | PDF (2.9 MB) | EPUB
  • 99 Views
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Article
Changes in Laboratory Indexes for Multiple Myeloma Patients Before and After Autologous Stem Cell Transplant
Rui Zhao, Jing Zhao, Yichuan Song, Wenxuan Fu, Qingtao Wang & Rui Zhang
Pages: 5779-5789
Published online: 04 Dec 2023
AbstractforChanges in Laboratory Indexes for Multiple Myeloma Patients Before and After Autologous Stem Cell Transplant | Full Text | References | PDF (5.1 MB) | EPUB
  • 134 Views
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REVIEW

Review
The Pivotal Role of Nrf2 Signal Axis in Intervertebral Disc Degeneration
Chunran Pan, Wenjie Hou, Xiaofeng Deng, Jiawei Liu, Ruimin Chi, Xingru Shang, Tao Xu & Xiaoxia Hao
Pages: 5819-5833
Published online: 04 Dec 2023
AbstractforThe Pivotal Role of Nrf2 Signal Axis in Intervertebral Disc Degeneration | Full Text | References | PDF (2.5 MB) | EPUB
  • 117 Views
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ORIGINAL RESEARCH

Article
Identification of Key Genes for Pyroptosis-Induced Salivary Gland Inflammation in Sjogren’s Syndrome Based on Microarray Data and Immunohistochemistry Analysis
Kaiyuan Zhang, Ziyue Luo, Xinchao Zhu, Xinyi Yao, Dingqi Lu, Liying Chen, Tao Hong, Yating Ren & Xinchang Wang
Pages: 5865-5879
Published online: 05 Dec 2023
AbstractforIdentification of Key Genes for Pyroptosis-Induced Salivary Gland Inflammation in Sjogren’s Syndrome Based on Microarray Data and Immunohistochemistry Analysis | Full Text | References | PDF (11.3 MB) | EPUB
  • 113 Views
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Article
Analysis and Verification of Glycosylation Characteristics of Septic Acute Kidney Injury
Si Chen & Hua Gan
Pages: 5881-5897
Published online: 05 Dec 2023
AbstractforAnalysis and Verification of Glycosylation Characteristics of Septic Acute Kidney Injury | Full Text | References | PDF (17.7 MB) | EPUB
  • 128 Views
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Article
Aucubin Alleviates Intervertebral Disc Degeneration by Repressing NF-κB-NLRP3 Inflammasome Activation in Endplate Chondrocytes
Kaiao Zou, Jun Ying, Huihui Xu, Qinghe Zeng, Haipeng Huang, Wenzhe Chen, Xuefeng Li, Pinger Wang, Hongting Jin, Ju Li & Yungang Wu
Pages: 5899-5913
Published online: 05 Dec 2023
AbstractforAucubin Alleviates Intervertebral Disc Degeneration by Repressing NF-κB-NLRP3 Inflammasome Activation in Endplate Chondrocytes | Full Text | References | PDF (10.6 MB) | EPUB
  • 128 Views
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Article
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models
Mu Wang, Jian Guo, Ailsa L Hart & Jia V Li
Pages: 5845-5864
Published online: 05 Dec 2023
AbstractforIndole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models | Full Text | References | PDF (16 MB) | EPUB
  • 347 Views
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Article
An Important Role in Novel Immune Mechanism and Diagnostic Model of Ankylosing Spondylitis: The CeRNA-ADRB2 Network
Feihong Huang, Zhiping Su & Chaojie Yu
Pages: 5915-5936
Published online: 05 Dec 2023
AbstractforAn Important Role in Novel Immune Mechanism and Diagnostic Model of Ankylosing Spondylitis: The CeRNA-ADRB2 Network | Full Text | References | PDF (20.9 MB) | EPUB
  • 127 Views
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Article
Prognostic Value of Platelet-to-Lymphocyte Ratio Combined with CHA2DS2-VASc Score for Nonvalvular Atrial Fibrillation Induced Cardiogenic Cerebral Embolism
Qian Fan, Ling Gao, Zhiquan Wang, Fabrice Yves Ndjana Lessomo & Gang Wang
Pages: 5937-5947
Published online: 05 Dec 2023
AbstractforPrognostic Value of Platelet-to-Lymphocyte Ratio Combined with CHA2DS2-VASc Score for Nonvalvular Atrial Fibrillation Induced Cardiogenic Cerebral Embolism | Full Text | References | PDF (4.1 MB) | EPUB
  • 97 Views
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CASE REPORT

Case Report
Coincidence of Systemic Lupus Erythematosus and ANCA-Associated Vasculitis: A Case Report with Perforation of Nasal Septum and Palate
Yurun Liu, Shengnan Yu, Sha Ma, Juan Yu, Dachen Zuo, Weiqing Zhao, Juan Wang & Jing Wang
Pages: 5949-5957
Published online: 05 Dec 2023
AbstractforCoincidence of Systemic Lupus Erythematosus and ANCA-Associated Vasculitis: A Case Report with Perforation of Nasal Septum and Palate | Full Text | References | PDF (1.9 MB) | EPUB
  • 112 Views
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ORIGINAL RESEARCH

Article
Plasma and Peritoneal Fluid Annexin A2 Levels in Patients with Endometriosis
Michal Zygarowicz, Joanna Kacperczyk-Bartnik, Janusz Sierdzinski, Cezary Wojtyla, Piotr Pierzynski, Grzegorz Manka, Mariusz Kiecka, Robert Z Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Michal Lipa, Damian Warzecha, Miroslaw Wielgos, Ewa Koc-Zorawska, Marcin Zorawski & Piotr Laudanski
Pages: 5959-5969
Published online: 06 Dec 2023
AbstractforPlasma and Peritoneal Fluid Annexin A2 Levels in Patients with Endometriosis | Full Text | References | PDF (1.1 MB) | EPUB
  • 169 Views
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REVIEW

Review
Macrophage Heterogeneity and Its Impact on Myocardial Ischemia-Reperfusion Injury: An Integrative Review
Shuwan Xu, Cong Xu, Jiahua Xu, Kun Zhang & Huanji Zhang
Pages: 5971-5987
Published online: 07 Dec 2023
AbstractforMacrophage Heterogeneity and Its Impact on Myocardial Ischemia-Reperfusion Injury: An Integrative Review | Full Text | References | PDF (2.7 MB) | EPUB
  • 165 Views
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ORIGINAL RESEARCH

Article
Synergistic Enhancement of Isoforskolin and Dexamethasone Against Sepsis and Acute Lung Injury Mouse Models
Yan Fang, Chuang Xiao, Lueli Wang, Youlan Wang, Jun Zeng, Yaping Liang, Rong Huang, Yunke Shi, Sha Wu, Xiaohua Du, Shibo Sun, Min Li, Yuanyuan Zheng, Hongxiang Wu, Qiuzhe Guo & Weimin Yang
Pages: 5989-6001
Published online: 07 Dec 2023
AbstractforSynergistic Enhancement of Isoforskolin and Dexamethasone Against Sepsis and Acute Lung Injury Mouse Models | Full Text | References | PDF (6.5 MB) | EPUB
  • 258 Views
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Article
A Pilot Study on Tocilizumab in Very-Late-Onset Myasthenia Gravis
Ting-Ting Yang, Ze-Yi Wang, Ze-Xin Fan, Bo-Yi Yuan, Lin Ma, Jian-Feng Lu, Pen-Ju Liu, Yang He & Guang-Zhi Liu
Pages: 5835-5843
Published online: 07 Dec 2023
AbstractforA Pilot Study on Tocilizumab in Very-Late-Onset Myasthenia Gravis | Full Text | References | PDF (2.4 MB) | EPUB
  • 131 Views
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REVIEW

Review
The Potential of Natural Compounds Regulating Autophagy in the Treatment of Osteoporosis
Yiwei Zhao, Zechao Qu, Songchuan Zhao, Yong Zhang, Yining Gong, Bo Zhang, Xiangcheng Gao, Dong Wang & Liang Yan
Pages: 6003-6021
Published online: 07 Dec 2023
AbstractforThe Potential of Natural Compounds Regulating Autophagy in the Treatment of Osteoporosis | Full Text | References | PDF (3 MB) | EPUB
  • 187 Views
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ORIGINAL RESEARCH

Article
Unveiling COVID-19 Secrets: Harnessing Cytokines as Powerful Biomarkers for Diagnosis and Predicting Severity
Blanka Wolszczak-Biedrzycka, Justyna Dorf, Marzena Wojewódzka-Żelezniakowicz, Małgorzata Żendzian-Piotrowska, Violetta Joanna Dymicka-Piekarska, Joanna Matowicka-Karna & Mateusz Maciejczyk
Pages: 6055-6070
Published online: 10 Dec 2023
AbstractforUnveiling COVID-19 Secrets: Harnessing Cytokines as Powerful Biomarkers for Diagnosis and Predicting Severity | Full Text | References | PDF (1.4 MB) | EPUB
  • 101 Views
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LETTER

Letter to the Editor
Clinical Significance of Mean Platelet Volume in Predicting the Therapeutic Effect of Splanchnic Neurolysis [Letter]
Da-Xiong Zeng
Pages: 6071-6072
Published online: 10 Dec 2023
CitationforClinical Significance of Mean Platelet Volume in Predicting the Therapeutic Effect of Splanchnic Neurolysis [Letter] | Full Text | References | PDF (278.4 KB) | EPUB
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ORIGINAL RESEARCH

Article
Platelet-to-Lymphocyte Ratio Improves the Predictive Ability of the Risk Score for Atrial Fibrillation Recurrence After Radiofrequency Ablation
Wenchao Huang, Huaxin Sun, Yan Tang, Yan Luo & Hanxiong Liu
Pages: 6023-6038
Published online: 10 Dec 2023
AbstractforPlatelet-to-Lymphocyte Ratio Improves the Predictive Ability of the Risk Score for Atrial Fibrillation Recurrence After Radiofrequency Ablation | Full Text | References | PDF (3.2 MB) | EPUB
  • 94 Views
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Article
Increased Systemic Immune-Inflammation Index Was Associated with Type 2 Diabetic Peripheral Neuropathy: A Cross-Sectional Study in the Chinese Population
Jia Li, Xing Zhang, Yi Zhang, Xiaofang Dan, Xian Wu, Yuxia Yang, Xiping Chen, Shengxi Li, Yong Xu, Qin Wan & Pijun Yan
Pages: 6039-6053
Published online: 10 Dec 2023
AbstractforIncreased Systemic Immune-Inflammation Index Was Associated with Type 2 Diabetic Peripheral Neuropathy: A Cross-Sectional Study in the Chinese Population | Full Text | References | PDF (2.1 MB) | EPUB
  • 861 Views
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REVIEW

Review
Exploring the Connectivity of Neurodegenerative Diseases: Microglia as the Center
Yan Wang, Limei Cui, He Zhao, Huhuifen He, Liang Chen, Xicheng Song, Dawei Liu, Jingjing Qiu & Yan Sun
Pages: 6107-6121
Published online: 12 Dec 2023
AbstractforExploring the Connectivity of Neurodegenerative Diseases: Microglia as the Center | Full Text | References | PDF (7.8 MB) | EPUB
  • 199 Views
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ORIGINAL RESEARCH

Article
Bioinformatics Prediction and Experimental Validation of the Role of Macrophage Polarization and Ferroptosis in Gestational Diabetes Mellitus
Chujun Chen, Zerui Yang & Zhikun Qiu
Pages: 6087-6105
Published online: 12 Dec 2023
AbstractforBioinformatics Prediction and Experimental Validation of the Role of Macrophage Polarization and Ferroptosis in Gestational Diabetes Mellitus | Full Text | References | PDF (18.8 MB) | EPUB
  • 163 Views
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Article
Single-Cell RNA Sequencing Reveals Roles of Fibroblasts During Intestinal Injury and Repair in Rats with Severe Acute Pancreatitis
Jing Wang, Changqin Xu, Hongwei Xu, Ruixia Wang, Tong Su & Shulei Zhao
Pages: 6073-6086
Published online: 12 Dec 2023
AbstractforSingle-Cell RNA Sequencing Reveals Roles of Fibroblasts During Intestinal Injury and Repair in Rats with Severe Acute Pancreatitis | Full Text | References | PDF (9.8 MB) | EPUB
  • 136 Views
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Article
A Predictive Model of New-Onset Atrial Fibrillation After Percutaneous Coronary Intervention in Acute Myocardial Infarction Based on the Lymphocyte to C-Reactive Protein Ratio
Zhicheng Gao, Jiaqi Bao, Liuyang Wu, Kaiyu Shen, Qiqi Yan, Lifang Ye & Lihong Wang
Pages: 6123-6137
Published online: 12 Dec 2023
AbstractforA Predictive Model of New-Onset Atrial Fibrillation After Percutaneous Coronary Intervention in Acute Myocardial Infarction Based on the Lymphocyte to C-Reactive Protein Ratio | Full Text | References | PDF (843.5 KB) | EPUB
  • 99 Views
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Article
Potential Role of Intrapulmonary Concomitant Lesions in Differentiating Non-Neoplastic and Neoplastic Ground Glass Nodules
Bin-Jie Fu, Xiao-Chuan Zhang, Fa-Jin Lv & Zhi-Gang Chu
Pages: 6155-6166
Published online: 12 Dec 2023
AbstractforPotential Role of Intrapulmonary Concomitant Lesions in Differentiating Non-Neoplastic and Neoplastic Ground Glass Nodules | Full Text | References | PDF (2.3 MB) | EPUB
  • 62 Views
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Article
Unveiling FOS as a Potential Diagnostic Biomarker and Emetine as a Prospective Therapeutic Agent for Diabetic Nephropathy
Jiaqiong Lin, Xiaoyong Li, Yan Lin, Zena Huang, Fei He & Fu Xiong
Pages: 6139-6153
Published online: 12 Dec 2023
AbstractforUnveiling FOS as a Potential Diagnostic Biomarker and Emetine as a Prospective Therapeutic Agent for Diabetic Nephropathy | Full Text | References | PDF (8.4 MB) | EPUB
  • 93 Views
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REVIEW

Review
Recent Advances on the Molecular Mechanism and Clinical Trials of Venous Thromboembolism
Shao-Li Huang, Hong-Yi Xin, Xiao-Yan Wang, Guang-Gui Feng, Fu-Qing Wu, Zhi-Peng Feng, Zhou Xing, Xi-He Zhang, Hong-Wu Xin & Wen-Ying Luo
Pages: 6167-6178
Published online: 14 Dec 2023
AbstractforRecent Advances on the Molecular Mechanism and Clinical Trials of Venous Thromboembolism | Full Text | References | PDF (1.3 MB) | EPUB
  • 143 Views
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ORIGINAL RESEARCH

Article
Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis
Yunbo Yan, Linqian Yu, Binyang Chen, Chang’an Cao, Hairong Zhao, Qiang Wang, De Xie, Yuemei Xi, Chenggui Zhang & Jidong Cheng
Pages: 6179-6193
Published online: 15 Dec 2023
AbstractforMastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis | Full Text | References | PDF (9 MB) | EPUB
  • 163 Views
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Article
RNA Sequencing and Bioinformatics Analysis to Reveal Potential Biomarkers in Patients with Combined Allergic Rhinitis and Asthma Syndrome
Zheng-Dao Mao, Zhi-Guang Liu, Yan Qian, Yu-Jia Shi, Lian-Zheng Zhou, Qian Zhang & Chun-Jian Qi
Pages: 6211-6225
Published online: 18 Dec 2023
AbstractforRNA Sequencing and Bioinformatics Analysis to Reveal Potential Biomarkers in Patients with Combined Allergic Rhinitis and Asthma Syndrome | Full Text | References | PDF (6 MB) | EPUB
  • 138 Views
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Article
Network Pharmacology and Experimental Validation of the Anti-Inflammatory Effect of Tingli Dazao Xiefei Decoction in Acute Lung Injury Treatment
Chengxi Zhang, Xiaoqian Li, Dan Gao, Huahe Zhu, Shun Wang, Bo Tan & Aidong Yang
Pages: 6195-6209
Published online: 18 Dec 2023
AbstractforNetwork Pharmacology and Experimental Validation of the Anti-Inflammatory Effect of Tingli Dazao Xiefei Decoction in Acute Lung Injury Treatment | Full Text | References | PDF (12.4 MB) | EPUB
  • 143 Views
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HYPOTHESIS

The Eradication of Carcinogenic Viruses in Established Solid Cancers
Zeev Elkoshi
Pages: 6227-6239
Published online: 19 Dec 2023
AbstractforThe Eradication of Carcinogenic Viruses in Established Solid Cancers | Full Text | References | PDF (2.3 MB) | EPUB
  • 200 Views
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ORIGINAL RESEARCH

Article
Identifying and Validating GSTM5 as an Immunogenic Gene in Diabetic Foot Ulcer Using Bioinformatics and Machine Learning
Hongshuo Shi, Xin Yuan, Guobin Liu & Weijing Fan
Pages: 6241-6256
Published online: 19 Dec 2023
AbstractforIdentifying and Validating GSTM5 as an Immunogenic Gene in Diabetic Foot Ulcer Using Bioinformatics and Machine Learning | Full Text | References | PDF (6.4 MB) | EPUB
  • 238 Views
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Article
Analysis of Correlation Between Serum Oncostatin-M and Disease Severity and Mortality in Hospitalized Patients with Community-Acquired Pneumonia
Peikun Teng, Xingyu Zhang, Hong Wang, Xiudi Han & Xuedong Liu
Pages: 6257-6269
Published online: 20 Dec 2023
AbstractforAnalysis of Correlation Between Serum Oncostatin-M and Disease Severity and Mortality in Hospitalized Patients with Community-Acquired Pneumonia | Full Text | References | PDF (2.7 MB) | EPUB
  • 57 Views
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Article
Neutrophil Percentage-to-Albumin Ratio and Risk of Mortality in Patients on Peritoneal Dialysis
Yi Yu, Zhong Zhong, Wenzhuo Yang, Jianwen Yu, Jianbo Li, Xingdi Guo, Jiasi Chen, Haiping Mao & Zhijian Li
Pages: 6271-6281
Published online: 21 Dec 2023
AbstractforNeutrophil Percentage-to-Albumin Ratio and Risk of Mortality in Patients on Peritoneal Dialysis | Full Text | References | PDF (4 MB) | EPUB
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REVIEW

Review
Fibroblast Insights into the Pathogenesis of Ankylosing Spondylitis
Zhenhua Liu, Mingxi Cai, Haoteng Ke, Huazong Deng, Weijia Ye, Tao Wang, Qifan Chen & Shuizhong Cen
Pages: 6301-6317
Published online: 21 Dec 2023
AbstractforFibroblast Insights into the Pathogenesis of Ankylosing Spondylitis | Full Text | References | PDF (3.7 MB) | EPUB
  • 104 Views
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ORIGINAL RESEARCH

Article
A Pilot Study About the Role of PANoptosis-Based Genes in Atherosclerosis Development
HongKui Chen, Xianwei Xie, Huazhen Xiao, Wenjia Liang, Zhi-Jie Lin, Biting Lin, Kai-Yang Lin, Chun Chen & Yansong Guo
Pages: 6283-6299
Published online: 21 Dec 2023
AbstractforA Pilot Study About the Role of PANoptosis-Based Genes in Atherosclerosis Development | Full Text | References | PDF (14.8 MB) | EPUB
  • 88 Views
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Article
Association of M-Type Phospholipase A2 Receptor Deposition in Kidney Tissue with Treatment Outcomes in Patients with Idiopathic Membranous Nephropathy
Ning-Qiu Xie, Yu-Lin Zhang, Zi-Li Zheng, Quan-Lin Zheng & Ruo-Ji Chen
Pages: 6319-6328
Published online: 21 Dec 2023
AbstractforAssociation of M-Type Phospholipase A2 Receptor Deposition in Kidney Tissue with Treatment Outcomes in Patients with Idiopathic Membranous Nephropathy | Full Text | References | PDF (495.4 KB) | EPUB
  • 51 Views
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Article
Active Fraction of Polyrhachis Vicina Roger (AFPR) Ameliorate Depression Induced Inflammation Response by FTO/miR-221-3p/SOCS1 Axis
Junhui He, Jiaxiu Xie, Guili Zhou, Chunlian Jia, Dongbo Han, Dongmei Li, Jie Wei, Yi Li, Renshan Huang, Chunlian Li, Bo Wang, Chao Wei, Qibiao Su, Kedao Lai & Guining Wei
Pages: 6329-6348
Published online: 22 Dec 2023
AbstractforActive Fraction of Polyrhachis Vicina Roger (AFPR) Ameliorate Depression Induced Inflammation Response by FTO/miR-221-3p/SOCS1 Axis | Full Text | References | PDF (15.2 MB) | EPUB
  • 119 Views
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REVIEW

Review
Research Progress on Application of Inonotus obliquus in Diabetic Kidney Disease
Shuyue Wang, Ruihua Wang, Rongshan Li & Yafeng Li
Pages: 6349-6359
Published online: 25 Dec 2023
AbstractforResearch Progress on Application of Inonotus obliquus in Diabetic Kidney Disease | Full Text | References | PDF (2.5 MB) | EPUB
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ORIGINAL RESEARCH

Article
APOL1 Induces Pyroptosis of Fibroblasts Through NLRP3/Caspase-1/GSDMD Signaling Pathway in Ulcerative Colitis
Fangqing Zhu, Sheng Li, Qiuping Gu, Ningsheng Xie & Yinxia Wu
Pages: 6385-6396
Published online: 26 Dec 2023
AbstractforAPOL1 Induces Pyroptosis of Fibroblasts Through NLRP3/Caspase-1/GSDMD Signaling Pathway in Ulcerative Colitis | Full Text | References | PDF (8.4 MB) | EPUB
  • 94 Views
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Article
Extracellular Vesicle Content Changes Induced by Melatonin Promote Functional Recovery of Pancreatic Beta Cells in Acute Pancreatitis
Yuming Shao, Wenxiang Wu, Fangzhou Fan, Haifeng Liu, Yongliang Ming, Wangwei Liao, Chunyu Bai & Yuhua Gao
Pages: 6397-6413
Published online: 26 Dec 2023
AbstractforExtracellular Vesicle Content Changes Induced by Melatonin Promote Functional Recovery of Pancreatic Beta Cells in Acute Pancreatitis | Full Text | References | PDF (11.2 MB) | EPUB
  • 107 Views
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Article
The Combined Effect of Systemic Immune-Inflammation Index and Type 2 Diabetes Mellitus on the Prognosis of Patients Undergoing Percutaneous Coronary Intervention: A Large-Scale Cohort Study
Xiaohui Bian, Jining He, Rui Zhang, Sheng Yuan & Kefei Dou
Pages: 6415-6429
Published online: 27 Dec 2023
AbstractforThe Combined Effect of Systemic Immune-Inflammation Index and Type 2 Diabetes Mellitus on the Prognosis of Patients Undergoing Percutaneous Coronary Intervention: A Large-Scale Cohort Study | Full Text | References | PDF (3.6 MB) | EPUB
  • 123 Views
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Article
Neutrophil Extracellular Trap is Surrogate Biomarker for Prognosis and Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer
Wentao Zhong, Qianyu Wang, Xiaofei Shen, Yuan Lv, Liang Sun, Ran An, Hongyan Zhu, Huiyun Cai, Gang Chen, Aijun Liu & Junfeng Du
Pages: 6443-6455
Published online: 27 Dec 2023
AbstractforNeutrophil Extracellular Trap is Surrogate Biomarker for Prognosis and Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer | Full Text | References | PDF (5.9 MB) | EPUB
  • 101 Views
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Article
Associations Between Resolvin D1 and Culprit Plaque Morphologies: An Optical Coherence Tomography Study in Patients with ST-Segment Elevation Myocardial Infarction
Runzhen Chen, Jiannan Li, Zhaoxue Sheng, Jinying Zhou, Ying Wang, Xiaoxiao Zhao, Nan Li, Weida Liu, Chen Liu, Peng Zhou, Yi Chen, Shaodi Yan, Li Song, Hongbing Yan & Hanjun Zhao
Pages: 6457-6467
Published online: 28 Dec 2023
AbstractforAssociations Between Resolvin D1 and Culprit Plaque Morphologies: An Optical Coherence Tomography Study in Patients with ST-Segment Elevation Myocardial Infarction | Full Text | References | PDF (3 MB) | EPUB
  • 88 Views
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REVIEW

Review
Progress in Research on the Mechanisms and Interventions of Phlebitis from the Perspective of Vascular Endothelial Cell and Signaling Pathway
Ling-Ling Zhu, Yan-hong Wang & Quan Zhou
Pages: 6469-6481
Published online: 28 Dec 2023
AbstractforProgress in Research on the Mechanisms and Interventions of Phlebitis from the Perspective of Vascular Endothelial Cell and Signaling Pathway | Full Text | References | PDF (2.7 MB) | EPUB
  • 275 Views
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ORIGINAL RESEARCH

Article
Effect of Fipronil Exposure on Hematological Aspects of Rhesus Monkeys (Macaca mulatta): Risk and Toxicity Assessment in Agro-Workers
Nazeer Hussain Khan, Enshe Jiang & Irfan Zia Qureshi
Pages: 5755-5765
Published online: 28 Dec 2023
AbstractforEffect of Fipronil Exposure on Hematological Aspects of Rhesus Monkeys (Macaca mulatta): Risk and Toxicity Assessment in Agro-Workers | Full Text | References | PDF (3.8 MB) | EPUB
  • 129 Views
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LETTER

Letter to the Editor
Prognostic Value of Fibrinogen-to-Albumin Ratio in Coronary Three-Vessel Disease [Letter]
Yanli Guo & Yuechou Nong
Pages: 6483-6484
Published online: 28 Dec 2023
CitationforPrognostic Value of Fibrinogen-to-Albumin Ratio in Coronary Three-Vessel Disease [Letter] | Full Text | References | PDF (274.8 KB) | EPUB
  • 46 Views
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REVIEW

Review
The Management of Diabetes with Hyperuricemia: Can We Hit Two Birds with One Stone?
Yunyang Wang & Jie Lu
Pages: 6431-6441
Published online: 29 Dec 2023
AbstractforThe Management of Diabetes with Hyperuricemia: Can We Hit Two Birds with One Stone? | Full Text | References | PDF (1.6 MB) | EPUB
  • 173 Views
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ORIGINAL RESEARCH

Article
ANGPTL4 May Regulate the Crosstalk Between Intervertebral Disc Degeneration and Type 2 Diabetes Mellitus: A Combined Analysis of Bioinformatics and Rat Models
Yan Chen, Han Du, Xin Wang, Baixing Li, Xuzhuo Chen, Xiao Yang, Changqing Zhao & Jie Zhao
Pages: 6361-6384
Published online: 08 Jan 2024
AbstractforANGPTL4 May Regulate the Crosstalk Between Intervertebral Disc Degeneration and Type 2 Diabetes Mellitus: A Combined Analysis of Bioinformatics and Rat Models | Full Text | References | PDF (19.5 MB) | EPUB
  • 114 Views
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