Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 2 (2012)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 2 (2012)

See all volumes and issues
Vol 39, 2024 Vol 38, 2023 Vol 37, 2022 Vol 36, 2021 Vol 35, 2020 Vol 34, 2019 Vol 33, 2018 Vol 32, 2017 Vol 31, 2016 Vol 30, 2015 Vol 29, 2014 Vol 28, 2013 Volume 27, 2012 Vol 26, 2011 Vol 25, 2010 Vol 24, 2009 Vol 23, 2008 Vol 22, 2007 Vol 21, 2006 Vol 20, 2005 Vol 19, 2004 Vol 18, 2003 Vol 17, 2002 Vol 16, 2001 Vol 15, 1999-2000 Vol 14, 1998-1999 Vol 13, 1998 Vol 12, 1997 Vol 11, 1996-1997 Vol 10, 1995-1996 Vol 9, 1995 Vol 8, 1994-1995 Vol 7, 1993 Vol 6, 1992-1993 Vol 5, 1991 Vol 4, 1990-1991 Vol 3, 1989-1990 Vol 2, 1987-1989 Vol 1, 1985-1987
Download citations Download PDFs Download issue

Research Article

Article
The synthesis and biological activity of lipophilic derivatives of bicine conjugated with N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP)—an inhibitor of glucosamine-6-phosphate synthase
Dominik Koszel, Izabela Łącka, Katarzyna Kozłowska-Tylingo & Ryszard Andruszkiewicz
Pages: 167-173
Published online: 03 Jun 2011
AbstractforThe synthesis and biological activity of lipophilic derivatives of bicine conjugated with N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP)—an inhibitor of glucosamine-6-phosphate synthase | Full Text | References | PDF (677.6 KB)
  • 937 Views
  • 6 CrossRef citations
  • 0Altmetric
Free Access
Article
Exploring QSARs for inhibitory effect of a set of heterocyclic thrombin inhibitors by multilinear regression refined by artificial neural network and molecular docking simulations
Guillermo Ramírez-Galicia, Ramón Garduño-Juárez, José Correa-Basurto & Omar Deeb
Pages: 174-186
Published online: 03 Jun 2011
AbstractforExploring QSARs for inhibitory effect of a set of heterocyclic thrombin inhibitors by multilinear regression refined by artificial neural network and molecular docking simulations | Full Text | References | PDF (1.2 MB) | Supplemental
  • 619 Views
  • 7 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis, characterization and biological properties of thienyl derived triazole Schiff bases and their oxovanadium(IV) complexes
Zahid H. Chohan & Sajjad H. Sumrra
Pages: 187-193
Published online: 03 Jun 2011
AbstractforSynthesis, characterization and biological properties of thienyl derived triazole Schiff bases and their oxovanadium(IV) complexes | Full Text | References | PDF (732.5 KB)
  • 1133 Views
  • 22 CrossRef citations
  • 0Altmetric
Free Access
Article
Factors influencing the inhibition of protein kinases
Marielle Brockhoff, Jean-Christophe Hau, Patrizia Fontana, Catherine Zimmermann, Alain De Pover, Dirk Erdmann & Patrick Chène
Pages: 194-200
Published online: 03 Jun 2011
AbstractforFactors influencing the inhibition of protein kinases | Full Text | References | PDF (816.5 KB) | Supplemental
  • 780 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents
N. S. Hari Narayana Moorthy, Vipin Saxena, C. Karthikeyan & Piyush Trivedi
Pages: 201-207
Published online: 03 Jun 2011
AbstractforSynthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents | Full Text | References | PDF (651.8 KB)
  • 739 Views
  • 6 CrossRef citations
  • 0Altmetric
Free Access
Article
In vitro effects of some anabolic compounds on erythrocyte carbonic anhydrase I and II
Nahit Gençer, Adem Ergün & Dudu Demir
Pages: 208-210
Published online: 03 Jun 2011
AbstractforIn vitro effects of some anabolic compounds on erythrocyte carbonic anhydrase I and II | Full Text | References | PDF (576.4 KB)
  • 658 Views
  • 15 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis of 5-aryl-6-cinnamoyl-7-methyl-flavanones as novel antioxidants and antihyperlipidemics
Anindra Sharma, Namrata Anand, Rahul Sharma, Upma Chaturvedi, A. K. Khanna, Gitika Bhatia & Rama P. Tripathi
Pages: 211-222
Published online: 10 Jun 2011
AbstractforSynthesis of 5-aryl-6-cinnamoyl-7-methyl-flavanones as novel antioxidants and antihyperlipidemics | Full Text | References | PDF (1.2 MB) | Supplemental
  • 605 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access
Article
Antibacterial dimeric copper(II) complexes with chromone-derived compounds
Zahid H. Chohan, Mohammad S. Iqbal, Syed K. Aftab & A. Rauf
Pages: 223-231
Published online: 24 Jun 2011
AbstractforAntibacterial dimeric copper(II) complexes with chromone-derived compounds | Full Text | References | PDF (985.6 KB) | Supplemental
  • 631 Views
  • 12 CrossRef citations
  • 0Altmetric
Free Access
Article
Comparative study of the effect of green and roasted water extracts of mate (Ilex paraguariensis) on glucosyltransferase activity of Streptococcus mutans
Jim Battagim, Verônica Trícoli de Souza, Natália Reiko Sato Miyasaka, Ildenize Barbosa da Silva Cunha, Alexandra Christine Sawaya, Anna Maria Alves de Piloto Fernandes, Marcos Nogueira Eberlin, Marcelo Lima Ribeiro & Patrícia de Oliveira Carvalho
Pages: 232-240
Published online: 10 Jun 2011
AbstractforComparative study of the effect of green and roasted water extracts of mate (Ilex paraguariensis) on glucosyltransferase activity of Streptococcus mutans | Full Text | References | PDF (791.9 KB) | Supplemental
  • 1054 Views
  • 7 CrossRef citations
  • 0Altmetric
Free Access
Article
Fluorine bearing sydnones with styryl ketone group: synthesis and their possible analgesic and anti-inflammatory activities
Shreenivas Ramachandrarao Deshpande & Karkala Vasantakumar Pai
Pages: 241-248
Published online: 10 Jun 2011
AbstractforFluorine bearing sydnones with styryl ketone group: synthesis and their possible analgesic and anti-inflammatory activities | Full Text | References | PDF (731.5 KB)
  • 660 Views
  • 5 CrossRef citations
  • 0Altmetric
Free Access
Article
QSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity
B. K. Sharma, P. Singh, P. Pilania, M. Shekhawat & Y.S. Prabhakar
Pages: 249-260
Published online: 16 Jun 2011
AbstractforQSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity | Full Text | References | PDF (845.2 KB)
  • 713 Views
  • 4 CrossRef citations
  • 0Altmetric
Free Access
Article
Luteolin downregulates IL-1β-induced MMP-9 and -13 expressions in osteoblasts via inhibition of ERK signalling pathway
Hyekyung Yang, Qing Liu, Jong Hoon Ahn, Seon Beom Kim, Young Choong Kim, Sang Hyun Sung, Bang Yeon Hwang & Mi Kyeong Lee
Pages: 261-266
Published online: 16 Jun 2011
AbstractforLuteolin downregulates IL-1β-induced MMP-9 and -13 expressions in osteoblasts via inhibition of ERK signalling pathway | Full Text | References | PDF (697.3 KB)
  • 936 Views
  • 21 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis and antioxidant, cytotoxicity and antimicrobial activities of novel curcumin mimics
Babasaheb P. Bandgar, Shivkumar S. Jalde, Balaji L. Korbad, Sachin A. Patil, Hemant V. Chavan, Santosh N. Kinkar, Laxman K. Adsul, Sadanand N. Shringare & Shivraj H. Nile
Pages: 267-274
Published online: 16 Jun 2011
AbstractforSynthesis and antioxidant, cytotoxicity and antimicrobial activities of novel curcumin mimics | Full Text | References | PDF (631.5 KB)
  • 1127 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis and analgesic activity of some acetamide derivatives
Zafer Asim Kaplancikli, Mehlika Dilek Altintop, Gulhan Turan-Zitouni, Ahmet Ozdemir & Ozgur Devrim Can
Pages: 275-280
Published online: 10 Jun 2011
AbstractforSynthesis and analgesic activity of some acetamide derivatives | Full Text | References | PDF (725.8 KB)
  • 2116 Views
  • 14 CrossRef citations
  • 0Altmetric
Free Access
Article
Design, synthesis and SAR exploration of hybrid 4-chlorophenylthiazolyl-s-triazine as potential antimicrobial agents
Prashant Gahtori & Surajit K. Ghosh
Pages: 281-293
Published online: 10 Jun 2011
AbstractforDesign, synthesis and SAR exploration of hybrid 4-chlorophenylthiazolyl-s-triazine as potential antimicrobial agents | Full Text | References | PDF (887.8 KB)
  • 992 Views
  • 17 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis and exploration of QSAR model of 2-methyl-3-[2-(2-methylprop-1-en-1-yl)-1H-benzimidazol-1-yl]pyrimido[1,2-a]benzimidazol-4(3H)-one as potential antibacterial agents
Pratibha Sharma, Ashok Kumar, Manisha Sharma, Jitendra Singh, Prabal Bandyopadhyay, Manisha Sathe & M.P. Kaushik
Pages: 294-301
Published online: 23 Jun 2011
AbstractforSynthesis and exploration of QSAR model of 2-methyl-3-[2-(2-methylprop-1-en-1-yl)-1H-benzimidazol-1-yl]pyrimido[1,2-a]benzimidazol-4(3H)-one as potential antibacterial agents | Full Text | References | PDF (732.4 KB)
  • 1028 Views
  • 8 CrossRef citations
  • 0Altmetric
Free Access
Article
Synthesis of a novel series of L-isoserine derivatives as aminopeptidase N inhibitors
Kanghui Yang, Jinghong Fen, Hao Fang, Lei Zhang, Jianzhi Gong & Wenfang Xu
Pages: 302-310
Published online: 20 Jul 2011
AbstractforSynthesis of a novel series of L-isoserine derivatives as aminopeptidase N inhibitors | Full Text | References | PDF (1.1 MB)
  • 1196 Views
  • 4 CrossRef citations
  • 0Altmetric
Free Access

Short Communication

Novel phenoxyalkylcarboxylic acid derivatives as hypolipidaemic agents
Wei Li, Hao-yan Jia, Xin-hua He, Wei-guo Shi & Bo-hua Zhong
Pages: 311-318
Published online: 15 Nov 2011
AbstractforNovel phenoxyalkylcarboxylic acid derivatives as hypolipidaemic agents | Full Text | References | PDF (787.8 KB) | Supplemental
  • 1028 Views
  • 7 CrossRef citations
  • 0Altmetric
Free Access

Explore articles

Explore the most recently published articles

The activity of pyrazolo[4,3-e][1,2,4]triazine and pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures
Anna Szymanowska et al.
Article | Published online: 3 May 2024
Open Access
Discovery of novel FGFR4 inhibitors through a build-up fragment strategy
Jihyung Kim et al.
Brief Report | Published online: 24 Apr 2024
Open Access
Targeting bacterial growth in biofilm conditions: rational design of novel inhibitors to mitigate clinical and food contamination using QSAR
Maria Galvez-Llompart et al.
Article | Published online: 23 Apr 2024
Open Access
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells
Loredana Salerno et al.
Brief Report | Published online: 18 Apr 2024
Open Access