Autophagy, Volume 10, Issue 12 (2014)

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Autophagy, Volume 10, Issue 12 (2014)

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EDITOR'S CORNER

Editorial
CUET-ting edge research
Daniel P Orban & Daniel J Klionsky
Pages: 2097-2098
Published online: 28 Jan 2015
CitationforCUET-ting edge research | Full Text | References | PDF (42.2 KB)
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REVIEW

Autophagy and ethanol neurotoxicity
Jia Luo
Pages: 2099-2108
Published online: 28 Jan 2015
AbstractforAutophagy and ethanol neurotoxicity | Full Text | References | PDF (558.4 KB)
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BRIEF REPORT

Brief Report
IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis
Ana I Rovetta, Delfina Peña, Rodrigo E Hernández Del Pino, Gabriela M Recalde, Joaquín Pellegrini, Fabiana Bigi, Rosa M Musella, Domingo J Palmero, Marisa Gutierrez, María I Colombo & Verónica E García
Pages: 2109-2121
Published online: 28 Jan 2015
AbstractforIFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis | Full Text | References | PDF (857.6 KB) | Supplemental
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TRANSLATIONAL RESEARCH PAPER

Article
Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers
Sylvain Lefort, Carine Joffre, Yann Kieffer, Anne-Marie Givel, Brigitte Bourachot, Giulia Zago, Ivan Bieche, Thierry Dubois, Didier Meseure, Anne Vincent-Salomon, Jacques Camonis & Fatima Mechta-Grigoriou
Pages: 2122-2142
Published online: 28 Jan 2015
AbstractforInhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers | Full Text | References | PDF (1.4 MB) | Supplemental
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BASIC RESEARCH PAPERS

Article
Glycosome turnover in Leishmania major is mediated by autophagy
Benjamin Cull, Joseane Lima Prado Godinho, Juliany Cola Fernandes Rodrigues, Benjamin Frank, Uta Schurigt, Roderick AM Williams, Graham H Coombs & Jeremy C Mottram
Pages: 2143-2157
Published online: 28 Jan 2015
AbstractforGlycosome turnover in Leishmania major is mediated by autophagy | Full Text | References | PDF (1.3 MB)
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Open Access
Article
PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1
Zhenda Wang, Jia Hu, Ge Li, Liujing Qu, Qihua He, Yaxin Lou, Quansheng Song, Dalong Ma & Yingyu Chen
Pages: 2158-2170
Published online: 28 Jan 2015
AbstractforPHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1 | Full Text | References | PDF (1.6 MB) | Supplemental
  • 1901 Views
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Article
Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment
Anne-Maria Poehler, Wei Xiang, Philipp Spitzer, Verena Elisabeth Luise May, Holger Meixner, Edward Rockenstein, Oldriska Chutna, Tiago Fleming Outeiro, Juergen Winkler, Eliezer Masliah & Jochen Klucken
Pages: 2171-2192
Published online: 28 Jan 2015
AbstractforAutophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment | Full Text | References | PDF (3 MB) | Supplemental
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Article
Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF
Monique Bernard, Mélanie Dieudé, Bing Yang, Katia Hamelin, Katy Underwood & Marie-Josée Hébert
Pages: 2193-2207
Published online: 28 Jan 2015
AbstractforAutophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF | Full Text | References | PDF (1.2 MB) | Supplemental
  • 4010 Views
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Open Access
Article
Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury
Chinmoy Sarkar, Zaorui Zhao, Stephanie Aungst, Boris Sabirzhanov, Alan I Faden & Marta M Lipinski
Pages: 2208-2222
Published online: 28 Jan 2015
AbstractforImpaired autophagy flux is associated with neuronal cell death after traumatic brain injury | Full Text | References | PDF (1.5 MB) | Supplemental
  • 7040 Views
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Open Access
Article
ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis
Yuyan Xiong, Gautham Yepuri, Michael Forbiteh, Yi Yu, Jean-Pierre Montani, Zhihong Yang & Xiu-Fen Ming
Pages: 2223-2238
Published online: 28 Jan 2015
AbstractforARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis | Full Text | References | PDF (2.2 MB) | Supplemental
  • 5793 Views
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Open Access
Article
Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination
Congfeng Xu, Kuan Feng, Xiaonan Zhao, Shiqian Huang, Yiji Cheng, Liu Qian, Yanan Wang, Hongxing Sun, Min Jin, Tsung-Hsien Chuang & Yanyun Zhang
Pages: 2239-2250
Published online: 28 Jan 2015
AbstractforRegulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination | Full Text | References | PDF (1.2 MB)
  • 4100 Views
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Open Access
Article
Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila
Elena Morelli, Pierpaolo Ginefra, Valeria Mastrodonato, Galina V Beznoussenko, Tor Erik Rusten, David Bilder, Harald Stenmark, Alexandre A Mironov & Thomas Vaccari
Pages: 2251-2268
Published online: 28 Jan 2015
AbstractforMultiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila | Full Text | References | PDF (2.5 MB) | Supplemental
  • 5042 Views
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Open Access
Article
Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity
Martina Haller, Andreas K Hock, Evangelos Giampazolias, Andrew Oberst, Douglas R Green, Jayanta Debnath, Kevin M Ryan, Karen H Vousden & Stephen W G Tait
Pages: 2269-2278
Published online: 28 Jan 2015
AbstractforUbiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity | Full Text | References | PDF (648.7 KB) | Supplemental
  • 5686 Views
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Open Access
Article
TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control
Jemma Gatliff, Daniel East, James Crosby, Rosella Abeti, Robert Harvey, William Craigen, Peter Parker & Michelangelo Campanella
Pages: 2279-2296
Published online: 28 Jan 2015
AbstractforTSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control | Full Text | References | PDF (2 MB) | Supplemental
  • 7210 Views
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Open Access
Article
RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy
Natalie Spang, Anne Feldmann, Heike Huesmann, Fazilet Bekbulat, Verena Schmitt, Christof Hiebel, Ingrid Koziollek-Drechsler, Albrecht M Clement, Bernd Moosmann, Jennifer Jung, Christian Behrends, Ivan Dikic, Andreas Kern & Christian Behl
Pages: 2297-2309
Published online: 28 Jan 2015
AbstractforRAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy | Full Text | References | PDF (3.6 MB) | Supplemental
  • 5308 Views
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Open Access
Article
Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion
Hemma Brandstaetter, Chieko Kishi-Itakura, David A Tumbarello, Dietmar J Manstein & Folma Buss
Pages: 2310-2323
Published online: 28 Jan 2015
AbstractforLoss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion | Full Text | References | PDF (1.8 MB) | Supplemental
  • 4091 Views
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Open Access
Article
New horizons in schizophrenia treatment: autophagy protection is coupled with behavioral improvements in a mouse model of schizophrenia
Avia Merenlender-Wagner, Zeev Shemer, Olga Touloumi, Roza Lagoudaki, Eliezer Giladi, Annie Andrieux, Nikolaos C Grigoriadis & Illana Gozes
Pages: 2324-2332
Published online: 28 Jan 2015
AbstractforNew horizons in schizophrenia treatment: autophagy protection is coupled with behavioral improvements in a mouse model of schizophrenia | Full Text | References | PDF (476.3 KB)
  • 1961 Views
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Article
HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)
Sanda Mimouna, Marie Bazin, Baharia Mograbi, Arlette Darfeuille-Michaud, Patrick Brest, Paul Hofman & Valérie Vouret-Craviari
Pages: 2333-2345
Published online: 28 Jan 2015
AbstractforHIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC) | Full Text | References | PDF (1 MB) | Supplemental
  • 3025 Views
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Open Access
Article
A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089
Khushboo Sharma, Rachel W Goehe, Xu Di, Mark Anthony Hicks II, Suzy V Torti, Frank M Torti, Hisashi Harada & David A. Gewirtz
Pages: 2346-2361
Published online: 28 Jan 2015
AbstractforA novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089 | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2641 Views
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Article
Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine
Ljubica Vucicevic, Maja Misirkic-Marjanovic, Verica Paunovic, Tamara Kravic-Stevovic, Tamara Martinovic, Darko Ciric, Nadja Maric, Sasa Petricevic, Ljubica Harhaji-Trajkovic, Vladimir Bumbasirevic & Vladimir Trajkovic
Pages: 2362-2378
Published online: 28 Jan 2015
AbstractforAutophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine | Full Text | References | PDF (1.9 MB)
  • 4679 Views
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AUTOPHAGIC PUNCTA

Article Commentary
Autophagy in the rejection of self-pollen in the mustard family
Darya Safavian & Daphne Goring
Pages: 2379-2380
Published online: 28 Jan 2015
AbstractforAutophagy in the rejection of self-pollen in the mustard family | Full Text | PDF (143.9 KB)
  • 725 Views
  • 3 CrossRef citations
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Article Commentary
A new class of ubiquitin-Atg8 receptors involved in selective autophagy and polyQ protein clearance
Kefeng Lu, Ivan Psakhye & Stefan Jentsch
Pages: 2381-2382
Published online: 28 Jan 2015
AbstractforA new class of ubiquitin-Atg8 receptors involved in selective autophagy and polyQ protein clearance | Full Text | PDF (94.4 KB)
  • 2457 Views
  • 38 CrossRef citations
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Article Commentary
Discovery and implications of transcellular mitophagy
Chung-ha O. Davis & Nicholas Marsh-Armstrong
Pages: 2383-2384
Published online: 28 Jan 2015
AbstractforDiscovery and implications of transcellular mitophagy | Full Text | PDF (121.8 KB)
  • 2310 Views
  • 28 CrossRef citations
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Article Commentary
Calcium channel blockers as potential therapeutics for obesity-associated autophagy defects and fatty liver pathologies
Hwan-Woo Park & Jun Hee Lee
Pages: 2385-2386
Published online: 28 Jan 2015
AbstractforCalcium channel blockers as potential therapeutics for obesity-associated autophagy defects and fatty liver pathologies | Full Text | PDF (45.5 KB)
  • 3544 Views
  • 53 CrossRef citations
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Article Commentary
TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction
Michael A Mandell, Tomonori Kimura, Ashish Jain, Terje Johansen & Vojo Deretic
Pages: 2387-2388
Published online: 28 Jan 2015
AbstractforTRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction | Full Text | PDF (138.8 KB)
  • 3080 Views
  • 56 CrossRef citations
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Article Commentary
DRAM1 promotes the targeting of mycobacteria to selective autophagy
Annemarie H Meijer & Michiel van der Vaart
Pages: 2389-2391
Published online: 28 Jan 2015
AbstractforDRAM1 promotes the targeting of mycobacteria to selective autophagy | Full Text | PDF (235.4 KB)
  • 2665 Views
  • 17 CrossRef citations
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Open Access

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