Bioengineered, Volume 13, Issue 1 (2022)

Browse this journal
Sample our Engineering & Technology journals, sign in here to start your access, latest two full volumes FREE to you for 14 days

Bioengineered, Volume 13, Issue 1 (2022)

See all volumes and issues
Vol 15, 2024 Vol 14, 2023 Volume 13, 2022 Vol 12, 2021 Vol 11, 2019-2020 Vol 10, 2019 Vol 9, 2018 Vol 8, 2017 Vol 7, 2016 Vol 6, 2015 Vol 5, 2014 Vol 4, 2013 Vol 3, 2012 Vol 2, 2011 Vol 1, 2010
Download citations Download PDFs

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA DCST1-AS1/hsa-miR-582-5p/HMGB1 axis regulates colorectal cancer progression
Long huang & Gang Dai
Pages: 12-26
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Long non-coding RNA DCST1-AS1/hsa-miR-582-5p/HMGB1 axis regulates colorectal cancer progression | PDF (6 MB) | Supplemental
  • 2191 Views
  • 16 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Exosomal microRNA⁃93⁃3p secreted by bone marrow mesenchymal stem cells downregulates apoptotic peptidase activating factor 1 to promote wound healing
Caiqi Shen, Changbo Tao, Aijun Zhang, Xueyang Li, Yanping Guo, Hanxiao Wei, Qichuan Yin, Qiang Li & Peisheng Jin
Pages: 27-37
Published online: 24 Dec 2021
AbstractforExosomal microRNA⁃93⁃3p secreted by bone marrow mesenchymal stem cells downregulates apoptotic peptidase activating factor 1 to promote wound healing | Full Text | References | PDF (3 MB) | EPUB
  • 2725 Views
  • 15 CrossRef citations
  • 0Altmetric
Open Access
Article
β-arrestin-2 alleviates rheumatoid arthritis injury by suppressing NLRP3 inflammasome activation and NF- κB pathway in macrophages
Feng Cao, Cheng Huang, Jiwei Cheng & Zhaochun He
Pages: 38-47
Published online: 27 Dec 2021
Abstractforβ-arrestin-2 alleviates rheumatoid arthritis injury by suppressing NLRP3 inflammasome activation and NF- κB pathway in macrophages | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 2346 Views
  • 11 CrossRef citations
  • 0Altmetric
Open Access
Article
Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway
Lei Sun, Hua Wang, Dan Xu, Shanshan Yu, Lin Zhang & Xiaopeng Li
Pages: 48-60
Published online: 29 Dec 2021
AbstractforLapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway | Full Text | References | PDF (2.9 MB) | EPUB
  • 6190 Views
  • 37 CrossRef citations
  • 0Altmetric
Open Access
Article
MACC1 regulates the AKT/STAT3 signaling pathway to induce migration, invasion, cancer stemness, and suppress apoptosis in cervical cancer cells
Jie Mei, ChengYa Zhu, LiuLiu Pan & Mian Li
Pages: 61-70
Published online: 23 Dec 2021
AbstractforMACC1 regulates the AKT/STAT3 signaling pathway to induce migration, invasion, cancer stemness, and suppress apoptosis in cervical cancer cells | Full Text | References | PDF (3.1 MB) | EPUB
  • 1834 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access
Article
Mechanisms of Dendrobium officinale polysaccharides in repairing gastric mucosal injuries based on mitogen-activated protein kinases (MAPK) signaling pathway
Sibu Ma, Qiong Wu, Zelin Zhao, Jiangyan Xiong, Jianjun Niu, Chunyan Liu, Tingjiang Liu, Yihui Chai, Xiangling Qu, Zili Ma, Liyan Zhang & Xiang Pu
Pages: 71-82
Published online: 29 Dec 2021
AbstractforMechanisms of Dendrobium officinale polysaccharides in repairing gastric mucosal injuries based on mitogen-activated protein kinases (MAPK) signaling pathway | Full Text | References | PDF (2.3 MB) | EPUB
  • 2506 Views
  • 16 CrossRef citations
  • 0Altmetric
Open Access
Article
MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway
Zhen Zhai, Tianlong Mu, Lina Zhao, Yiliang Li, Dongsheng Zhu & Yanshu Pan
Pages: 83-95
Published online: 24 Dec 2021
AbstractforMiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway | Full Text | References | PDF (3.7 MB) | EPUB
  • 2506 Views
  • 22 CrossRef citations
  • 0Altmetric
Open Access
Article
Myosin light chain 9 promotes the proliferation, invasion, migration and angiogenesis of colorectal cancer cells by binding to Yes-associated protein 1 and regulating Hippo signaling
Min Feng, Ningfei Dong, Xin Zhou, Lihong Ma & Rui Xiang
Pages: 96-106
Published online: 03 Jan 2022
AbstractforMyosin light chain 9 promotes the proliferation, invasion, migration and angiogenesis of colorectal cancer cells by binding to Yes-associated protein 1 and regulating Hippo signaling | Full Text | References | PDF (3 MB) | EPUB
  • 2175 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
B7 family member H4 induces epithelial-mesenchymal transition and promotes the proliferation, migration and invasion of colorectal cancer cells
Yuzhen Yin, Lili Shi, Jing Yang, Hui Wang, Hang Yang & Qiang Wang
Pages: 107-118
Published online: 25 Dec 2021
AbstractforB7 family member H4 induces epithelial-mesenchymal transition and promotes the proliferation, migration and invasion of colorectal cancer cells | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1523 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
MiR-410-3p facilitates Angiotensin II–induced cardiac hypertrophy by targeting Smad7
Guizhi Jia, Chunguang Liang, Wenhui Li & Hongliang Dai
Pages: 119-127
Published online: 24 Dec 2021
AbstractforMiR-410-3p facilitates Angiotensin II–induced cardiac hypertrophy by targeting Smad7 | Full Text | References | PDF (1.3 MB) | EPUB
  • 1473 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Clinical practice of epidermal growth factor receptor-tyrosine kinase inhibitor targeted drugs combined with gadolinium oxide nanoparticles in the treatment of non-small cell lung cancer
Xuan Zhou, Ting Jin, Likun Wang, Erlin Zhao & Xuyang Xiao
Pages: 128-139
Published online: 25 Dec 2021
AbstractforRETRACTED ARTICLE: Clinical practice of epidermal growth factor receptor-tyrosine kinase inhibitor targeted drugs combined with gadolinium oxide nanoparticles in the treatment of non-small cell lung cancer | PDF (4.2 MB)
  • 1424 Views
  • 2 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Long non-coding RNA HCG11 enhances osteosarcoma phenotypes by sponging miR-1245b-5p that directly inhibits plakophilin 2
Hao Yan, Yong Zhou, Zhujiang Chen, Xiaokang Yan & Ling Zhu
Pages: 140-154
Published online: 23 Dec 2021
AbstractforLong non-coding RNA HCG11 enhances osteosarcoma phenotypes by sponging miR-1245b-5p that directly inhibits plakophilin 2 | Full Text | References | PDF (7 MB) | EPUB
  • 1301 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation
Ming Yao, Feng Li, Liang Xu, Li Ma & Shutong Zhang
Pages: 155-163
Published online: 24 Dec 2021
Abstractfor24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation | Full Text | References | PDF (1.2 MB) | EPUB
  • 1461 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
Icariin activates autophagy to trigger TGFβ1 upregulation and promote angiogenesis in EA.hy926 human vascular endothelial cells
Xiaolong Li, Yujie Wen, Liyuan Sheng, Rui Guo, Yanli Zhang & Longquan Shao
Pages: 164-177
Published online: 23 Dec 2021
AbstractforIcariin activates autophagy to trigger TGFβ1 upregulation and promote angiogenesis in EA.hy926 human vascular endothelial cells | Full Text | References | PDF (3.4 MB) | EPUB
  • 2024 Views
  • 9 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long noncoding RNA UBA6-AS1 inhibits the malignancy of ovarian cancer cells via suppressing the decay of UBA6 mRNA
Yaogang Wang & Zhigao Chen
Pages: 178-189
Published online: 24 Dec 2021
AbstractforRETRACTED ARTICLE: Long noncoding RNA UBA6-AS1 inhibits the malignancy of ovarian cancer cells via suppressing the decay of UBA6 mRNA | PDF (5.3 MB)
  • 1773 Views
  • 9 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer
Wenjun Xie, Ying Sun, Yu Zeng, Linfei Hu, Jingtai Zhi, Hang Ling, Xiangqian Zheng, Xianhui Ruan & Ming Gao
Pages: 190-205
Published online: 29 Dec 2021
AbstractforComprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer | Full Text | References | PDF (5.5 MB) | EPUB | Supplemental
  • 2593 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
C1q/tumor necrosis factor related protein 6 (CTRP6) regulates the phenotypes of high glucose-induced gestational trophoblast cells via peroxisome proliferator-activated receptor gamma (PPARγ) signaling
Jin Zhang & Wen-Pei Bai
Pages: 206-216
Published online: 29 Dec 2021
AbstractforC1q/tumor necrosis factor related protein 6 (CTRP6) regulates the phenotypes of high glucose-induced gestational trophoblast cells via peroxisome proliferator-activated receptor gamma (PPARγ) signaling | Full Text | References | PDF (3.4 MB) | EPUB
  • 1559 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
Octreotide activates autophagy to alleviate lipopolysaccharide-induced human pulmonary epithelial cell injury by inhibiting the protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway
Sumian Zhang, Cijun Tang & Xuebin Wang
Pages: 217-226
Published online: 26 Dec 2021
AbstractforOctreotide activates autophagy to alleviate lipopolysaccharide-induced human pulmonary epithelial cell injury by inhibiting the protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway | Full Text | References | PDF (3 MB) | EPUB
  • 1462 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access
Article
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter
Shen Zheng, Ran Wu, Yunlong Deng & Qiang Zhang
Pages: 227-241
Published online: 29 Dec 2021
AbstractforDihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter | Full Text | References | PDF (5.8 MB) | EPUB
  • 1660 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
Hyperoxia induces alveolar epithelial cell apoptosis by regulating mitochondrial function through small mothers against decapentaplegic 3 (SMAD3) and extracellular signal-regulated kinase 1/2 (ERK1/2)
Jun Jiang, Juan Wang, Cen Li, Lianqin Mo & Dong Huang
Pages: 242-252
Published online: 25 Dec 2021
AbstractforHyperoxia induces alveolar epithelial cell apoptosis by regulating mitochondrial function through small mothers against decapentaplegic 3 (SMAD3) and extracellular signal-regulated kinase 1/2 (ERK1/2) | Full Text | References | PDF (2.4 MB) | EPUB
  • 1435 Views
  • 9 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
Regulatory network controls microbial biofilm development, with Candida albicans as a representative: from adhesion to dispersal
Zhenbo Xu, Tengyi Huang, Min Du, Thanapop Soteyome, Haifeng Lan, Wei Hong, Fang Peng, Xin Fu, Gongyong Peng, Junyan Liu & Birthe V. Kjellerup
Pages: 253-267
Published online: 14 Jan 2022
AbstractforRegulatory network controls microbial biofilm development, with Candida albicans as a representative: from adhesion to dispersal | Full Text | References | PDF (581.7 KB) | EPUB
  • 2633 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Dehydroevodiamine suppresses inflammatory responses in adjuvant-induced arthritis rats and human fibroblast-like synoviocytes
Yufang Dai, Jiaoe Sheng, Sanshan He, Qingchao Wu, Yunlong Wang & Linchong Su
Pages: 268-279
Published online: 27 Dec 2021
AbstractforRETRACTED ARTICLE: Dehydroevodiamine suppresses inflammatory responses in adjuvant-induced arthritis rats and human fibroblast-like synoviocytes | PDF (5.8 MB) | Supplemental
  • 1901 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: LncRNA SOX2-OTinhibitionprotects against myocardialischemia/reperfusion-inducedinjury via themicroRNA-186-5p (miR-186-5p)/Yin Yang 1 (YY1)pathway
Pengjie Yang, Kun Liang, Weisong Wang, Dehua Zhou, Yuan Chen, Xueyan Jiang, Rong Fu, Benben Zhu & Xuefeng Lin
Pages: 280-290
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: LncRNA SOX2-OTinhibitionprotects against myocardialischemia/reperfusion-inducedinjury via themicroRNA-186-5p (miR-186-5p)/Yin Yang 1 (YY1)pathway | PDF (4.5 MB)
  • 1510 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Pregnancy-associated plasma protein-A (PAPPA) promotes breast cancer progression
Jun Zhang, Yuan Zhang, Lanjiang Li, Yinghua Nian, Ying Chen, Ruoxia Shen & Xiaoyan Ma
Pages: 291-307
Published online: 03 Jan 2022
AbstractforPregnancy-associated plasma protein-A (PAPPA) promotes breast cancer progression | Full Text | References | PDF (6.4 MB) | EPUB
  • 2372 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
CircSLC7A6 promotes the progression of Wilms’ tumor via microRNA-107/ ABL proto-oncogene 2 axis
Jiaju Xu, Ying Hao, Xingjuan Gao, Yanqiu Wu, Yanjie Ding & Baohong Wang
Pages: 308-318
Published online: 03 Jan 2022
AbstractforCircSLC7A6 promotes the progression of Wilms’ tumor via microRNA-107/ ABL proto-oncogene 2 axis | Full Text | References | PDF (3.3 MB) | EPUB
  • 1246 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: miR-134-5p promotes inflammation and apoptosis of trophoblast cells via regulating FOXP2 transcription in gestational diabetes mellitus
Weiqi Ke, Yixiang Chen, Lijing Zheng, Yuting Zhang, Yudan Wu & Li Li
Pages: 319-330
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: miR-134-5p promotes inflammation and apoptosis of trophoblast cells via regulating FOXP2 transcription in gestational diabetes mellitus | PDF (4.4 MB)
  • 1788 Views
  • 12 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
AZD3759 enhances radiation effects in non-small-cell lung cancer by a synergistic blockade of epidermal growth factor receptor and Janus kinase-1
Ruing Zhao, Wei Yin, Qingqing Yu, Yanjiao Mao, Qinghua Deng, Ke Zhang & Shenglin Ma
Pages: 331-344
Published online: 30 Dec 2021
AbstractforAZD3759 enhances radiation effects in non-small-cell lung cancer by a synergistic blockade of epidermal growth factor receptor and Janus kinase-1 | Full Text | References | PDF (2.4 MB) | EPUB
  • 1927 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis
Jihui Zhang, Hongwei Lei & Xiu Li
Pages: 345-356
Published online: 29 Dec 2021
AbstractforThe protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis | Full Text | References | PDF (1.2 MB) | EPUB
  • 2072 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
1α,25(OH)2D3(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis
Zhiyu Li, Biyun Xu, Yuexin Sun, Lanbo Zhou, Yue Tao, Wenjun Hou, Jun Bao, Jun Liu & Weixin Fan
Pages: 357-369
Published online: 03 Jan 2022
Abstractfor1α,25(OH)2D3(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis | Full Text | References | PDF (2.9 MB) | EPUB
  • 1692 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access
Article
MicroRNA miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture by inhibiting the glutamate AMPA receptor subunit 1 gene (GRIA1)
Meng Zhao, Junli Dong, Yuanmei Liao, Guoyong Lu, Wei Pan, Hansong Zhou, Xiaohua Zuo & Ben Shan
Pages: 370-382
Published online: 03 Jan 2022
AbstractforMicroRNA miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture by inhibiting the glutamate AMPA receptor subunit 1 gene (GRIA1) | Full Text | References | PDF (4.6 MB) | EPUB
  • 1494 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
Xiaoyao powder alleviates the hippocampal neuron damage in chronic unpredictable mild stress-induced depression model rats in hippocampus via connexin 43Cx43/glucocorticoid receptor/brain-derived neurotrophic factor signaling pathway
Yuanyuan Zhang, Yong Luo, Xuenan Hou, Kang Lu, Yanhong He, Baoying Yang & Yi Qin
Pages: 383-394
Published online: 11 Jan 2022
AbstractforXiaoyao powder alleviates the hippocampal neuron damage in chronic unpredictable mild stress-induced depression model rats in hippocampus via connexin 43Cx43/glucocorticoid receptor/brain-derived neurotrophic factor signaling pathway | Full Text | References | PDF (2.7 MB) | EPUB
  • 2461 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Interference of KLF9 relieved the development of gestational diabetes mellitus by upregulating DDAH2
Weixia Chen, Huiqin Wang, Jing Liu & Kaixia Li
Pages: 395-406
Published online: 29 Dec 2021
AbstractforRETRACTED ARTICLE: Interference of KLF9 relieved the development of gestational diabetes mellitus by upregulating DDAH2 | PDF (5.1 MB)
  • 2070 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: The myocardial infarction-associated transcript 2 inhibits lipid accumulation and promotes cholesterol efflux in oxidized low-density lipoprotein-induced THP-1-derived macrophages via inhibiting mitogen-activated protein kinase signaling and activating the nuclear factor erythroid-related factor 2 signaling pathway
Fangxiang Mu, Yuqing Wang, Hong Wu, Qingxia You & Daimin Zhang
Pages: 407-417
Published online: 29 Dec 2021
AbstractforRETRACTED ARTICLE: The myocardial infarction-associated transcript 2 inhibits lipid accumulation and promotes cholesterol efflux in oxidized low-density lipoprotein-induced THP-1-derived macrophages via inhibiting mitogen-activated protein kinase signaling and activating the nuclear factor erythroid-related factor 2 signaling pathway | PDF (5 MB)
  • 1799 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
E2F transcription factor 1/small nucleolar RNA host gene 18/microRNA-338-5p/forkhead box D1: an important regulatory axis in glioma progression
Quanfeng Ma & Tianhao Yang
Pages: 418-430
Published online: 27 Dec 2021
AbstractforE2F transcription factor 1/small nucleolar RNA host gene 18/microRNA-338-5p/forkhead box D1: an important regulatory axis in glioma progression | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1492 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Saxagliptin enhances osteogenic differentiation in MC3T3-E1 cells, dependent on the activation of AMP-activated protein kinase α (AMPKα)/runt-related transcription factor-2 (Runx-2)
Qiang Wang, Xiaoxing Xie, Dehua Zhang, Feng Mao, Shaobo Wang & Yi Liao
Pages: 431-439
Published online: 04 Jan 2022
AbstractforRETRACTED ARTICLE: Saxagliptin enhances osteogenic differentiation in MC3T3-E1 cells, dependent on the activation of AMP-activated protein kinase α (AMPKα)/runt-related transcription factor-2 (Runx-2) | PDF (2.6 MB)
  • 1455 Views
  • 15 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Circ_0005320 promotes oral squamous cell carcinoma tumorigenesis by sponging microRNA-486-3p and microRNA-637
Xiaotao Zheng, Fang Du, Xuepeng Gong & Ping Xu
Pages: 440-454
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Circ_0005320 promotes oral squamous cell carcinoma tumorigenesis by sponging microRNA-486-3p and microRNA-637 | PDF (7.5 MB)
  • 1330 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Co-treatment with miR-21-5p inhibitor and Aurora kinase inhibitor reversine suppresses breast cancer progression by targeting sprouty RTK signaling antagonist 2
Yue Zhang, Yaoyi Wang, Jun Xue, Wanping Liang, Zhisheng Zhang, Xiuming Yang, Zhifei Qiao, Yang Jiang, Junping Wang, Xuchen Cao & Peng Chen
Pages: 455-468
Published online: 30 Dec 2021
AbstractforCo-treatment with miR-21-5p inhibitor and Aurora kinase inhibitor reversine suppresses breast cancer progression by targeting sprouty RTK signaling antagonist 2 | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1671 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access
Article
Circular RNA 0000654 facilitates the growth of gastric cancer cells through absorbing microRNA-149-5p to up-regulate inhibin-beta A
Han Liu & Wen Dai
Pages: 469-480
Published online: 31 Jan 2022
AbstractforCircular RNA 0000654 facilitates the growth of gastric cancer cells through absorbing microRNA-149-5p to up-regulate inhibin-beta A | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 1035 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
Nampt promotes fibroblast extracellular matrix degradation in stress urinary incontinence by inhibiting autophagy
Hui Zhang, Lu Wang, Yuancui Xiang, Yali Wang & Hongjuan Li
Pages: 481-495
Published online: 30 Dec 2021
AbstractforNampt promotes fibroblast extracellular matrix degradation in stress urinary incontinence by inhibiting autophagy | Full Text | References | PDF (3.6 MB) | EPUB
  • 1569 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: microRNA-10a-5p from gastric cancer cell-derived exosomes enhances viability and migration of human umbilical vein endothelial cells by targeting zinc finger MYND-type containing 11
Jiaxin Zhu, Shasha Du, Jianfeng Zhang, Guangzhao Huang, Lujia Dong, Enbo Ren & Dechun Liu
Pages: 496-507
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: microRNA-10a-5p from gastric cancer cell-derived exosomes enhances viability and migration of human umbilical vein endothelial cells by targeting zinc finger MYND-type containing 11 | PDF (5.5 MB) | Supplemental
  • 1781 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Lipocalin-2 silencing suppresses inflammation and oxidative stress of acute respiratory distress syndrome by ferroptosis via inhibition of MAPK/ERK pathway in neonatal mice
Xiaodong Wang, Chunhua Zhang, Na Zou, Qinghua Chen, Chaojun Wang, Xu Zhou, Li Luo, Haibin Qi, Junhua Li, Zhiyan Liu, Jinghong Yi, Jing Li & Wei Liu
Pages: 508-520
Published online: 30 Dec 2021
AbstractforLipocalin-2 silencing suppresses inflammation and oxidative stress of acute respiratory distress syndrome by ferroptosis via inhibition of MAPK/ERK pathway in neonatal mice | Full Text | References | PDF (2.6 MB) | EPUB
  • 6130 Views
  • 37 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Mirtazapine prevents cell activation, inflammation, and oxidative stress against isoflurane exposure in microglia
Qi Wang, Meina Ma, Hong Yu, Hongmei Yu, Shuai Zhang & Rui Li
Pages: 521-530
Published online: 29 Dec 2021
AbstractforRETRACTED ARTICLE: Mirtazapine prevents cell activation, inflammation, and oxidative stress against isoflurane exposure in microglia | PDF (3.7 MB)
  • 2763 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Magnolol attenuates the locomotor impairment, cognitive deficit, and neuroinflammation in Alzheimer’s disease mice with brain insulin resistance via up-regulating miR-200c
Ting Chen, Lan Shou, Xiaowen Guo, Mingyang Wei, Hui Zheng & Tao Tao
Pages: 531-543
Published online: 30 Dec 2021
AbstractforMagnolol attenuates the locomotor impairment, cognitive deficit, and neuroinflammation in Alzheimer’s disease mice with brain insulin resistance via up-regulating miR-200c | Full Text | References | PDF (2.3 MB) | EPUB
  • 1927 Views
  • 11 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Protective effect of vasostatin-1 plasmid-like nanoparticles on aortic aneurysm and its mechanism
Pingshan Wang, Wei Wang, Xingxing Peng, Fugui Ruan & Shiyao Yang
Pages: 544-559
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Protective effect of vasostatin-1 plasmid-like nanoparticles on aortic aneurysm and its mechanism | PDF (6.9 MB)
  • 1280 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: F-box and WD repeat domain-containing 7 (FBXW7) mediates the hypoxia inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway to affect hypoxic-ischemic brain damage in neonatal rats
Ling Sun
Pages: 560-572
Published online: 24 Dec 2021
AbstractforRETRACTED ARTICLE: F-box and WD repeat domain-containing 7 (FBXW7) mediates the hypoxia inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway to affect hypoxic-ischemic brain damage in neonatal rats | PDF (5.1 MB)
  • 1728 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Long noncoding RNA Gm44593 attenuates oxidative stress from age-related hearing loss by regulating miR-29b/WNK1
Qian Li, Yanzi Zang, Zhanwei Sun, Wenqi Zhang & Hongjian Liu
Pages: 573-582
Published online: 30 Dec 2021
AbstractforLong noncoding RNA Gm44593 attenuates oxidative stress from age-related hearing loss by regulating miR-29b/WNK1 | Full Text | References | PDF (1.7 MB) | EPUB
  • 1319 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Methyl-CpG-binding protein 2 promotes osteogenic differentiation of bone marrow mesenchymal stem cells through regulating forkhead box F1/Wnt/β-Catenin axis
Weiqin Ji & Xiaotong Sun
Pages: 583-592
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Methyl-CpG-binding protein 2 promotes osteogenic differentiation of bone marrow mesenchymal stem cells through regulating forkhead box F1/Wnt/β-Catenin axis | PDF (6.5 MB)
  • 1792 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Protective effect of MiR-146 on renal injury following cardiopulmonary bypass in rats through mediating NF-κB signaling pathway
Hongbo Ma, Yanjiao Dong, Kun Sun, Shuo Wang & Zheng Zhang
Pages: 593-602
Published online: 29 Dec 2021
AbstractforRETRACTED ARTICLE: Protective effect of MiR-146 on renal injury following cardiopulmonary bypass in rats through mediating NF-κB signaling pathway | PDF (3.1 MB)
  • 1176 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Testis developmental related gene 1 promotes non-small-cell lung cancer through the microRNA-214-5p/Krüppel-like factor 5 axis
Xudong Lu, Nian Zhao, Guangjun Duan, Zhiyong Deng & Yimin Lu
Pages: 603-616
Published online: 27 Dec 2021
AbstractforRETRACTED ARTICLE: Testis developmental related gene 1 promotes non-small-cell lung cancer through the microRNA-214-5p/Krüppel-like factor 5 axis | PDF (7 MB) | Supplemental
  • 1258 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Effects of ginsenosides on memory impairment in propofol-anesthetized rats
Zhou-Liang Xu, GanLu Chen, XiangFei Liu, DaoFen Xie, Jie Zhang & YongGan Ying
Pages: 617-623
Published online: 29 Dec 2021
AbstractforEffects of ginsenosides on memory impairment in propofol-anesthetized rats | Full Text | References | PDF (522.8 KB) | EPUB
  • 1584 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: The abnormal expression of chromosomal region maintenance 1 (CRM1)-survivin axis in ovarian cancer and its related mechanisms regulating proliferation and apoptosis of ovarian cancer cells
Jing Zhang, Xinyan Xu, Yongfeng Chen, Xiaoju Guan, Hong Zhu & Yuhong Qi
Pages: 624-633
Published online: 03 Jan 2022
AbstractforRETRACTED ARTICLE: The abnormal expression of chromosomal region maintenance 1 (CRM1)-survivin axis in ovarian cancer and its related mechanisms regulating proliferation and apoptosis of ovarian cancer cells | PDF (4.2 MB)
  • 1274 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
MicroRNA (miR)-590-3p alleviates high-glucose induced renal tubular epithelial cell damage by targeting C-X3-C motif chemokine ligand 1 (CX3CL1) in diabetic nephropathy
Jie Yun, Jinyu Ren, Yufei Liu, Lijuan Dai, Liqun Song, Xiaopeng Ma, Shan Luo & Yexu Song
Pages: 634-644
Published online: 30 Dec 2021
AbstractforMicroRNA (miR)-590-3p alleviates high-glucose induced renal tubular epithelial cell damage by targeting C-X3-C motif chemokine ligand 1 (CX3CL1) in diabetic nephropathy | Full Text | References | PDF (830 KB) | EPUB
  • 1719 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
Transcription factor paired related homeobox 1 (PRRX1) activates matrix metalloproteinases (MMP)13, which promotes the dextran sulfate sodium-induced inflammation and barrier dysfunction of NCM460 cells
Xiujing Zhang, Lizhuan Ma, Ying Shen, Chao Zhang, Bingxu Hou & Yanli Zhou
Pages: 645-654
Published online: 30 Dec 2021
AbstractforTranscription factor paired related homeobox 1 (PRRX1) activates matrix metalloproteinases (MMP)13, which promotes the dextran sulfate sodium-induced inflammation and barrier dysfunction of NCM460 cells | Full Text | References | PDF (1.6 MB) | EPUB
  • 1731 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
Sitagliptin protects renal glomerular endothelial cells against high glucose-induced dysfunction and injury
Liang Xu & Fengmin Shao
Pages: 655-666
Published online: 30 Dec 2021
AbstractforSitagliptin protects renal glomerular endothelial cells against high glucose-induced dysfunction and injury | Full Text | References | PDF (1.8 MB) | EPUB
  • 2335 Views
  • 13 CrossRef citations
  • 0Altmetric
Open Access
Article
A novel circRNA-miRNA-mRNA network revealed exosomal circ-ATP10A as a biomarker for multiple myeloma angiogenesis
Manya Yu, Jie Yu, Yanyu Zhang, Xiaoqi Sun, Runjie Sun, Mengting Xia, Sumei Li & Xing Cui
Pages: 667-683
Published online: 30 Dec 2021
AbstractforA novel circRNA-miRNA-mRNA network revealed exosomal circ-ATP10A as a biomarker for multiple myeloma angiogenesis | Full Text | References | PDF (2.6 MB) | EPUB
  • 3200 Views
  • 24 CrossRef citations
  • 0Altmetric
Open Access
Article
Regulatory effects of miR-28 on osteogenic differentiation of human bone marrow mesenchymal stem cells
Min Wang, Tianming Dai, Qingqi Meng, Wen Wang & Siming Li
Pages: 684-696
Published online: 02 Jan 2022
AbstractforRegulatory effects of miR-28 on osteogenic differentiation of human bone marrow mesenchymal stem cells | Full Text | References | PDF (2.2 MB) | EPUB
  • 1205 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
Identification of key immune genes for sepsis-induced ARDS based on bioinformatics analysis
Ye Chen, Chenhui Qiu & Wanru Cai
Pages: 697-708
Published online: 30 Dec 2021
AbstractforIdentification of key immune genes for sepsis-induced ARDS based on bioinformatics analysis | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 3171 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Knockdown of small nucleolar RNA host gene 10 (SNHG10) alleviates the injury of human neuroblastoma cells via the miR-1277-5p/insulin substrate receptor 2 axis
Zhaoming Sun, Lixiang Song & Jiazhen Li
Pages: 709-720
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Knockdown of small nucleolar RNA host gene 10 (SNHG10) alleviates the injury of human neuroblastoma cells via the miR-1277-5p/insulin substrate receptor 2 axis | PDF (5 MB)
  • 1197 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Loss of Ras GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) inhibits the progression of ovarian cancer in coordination with ubiquitin-specific protease 10 (USP10)
Mengyuan Li, Yan Tang, Xinzhao Zuo, Silin Meng & Ping Yi
Pages: 721-734
Published online: 30 Dec 2021
AbstractforLoss of Ras GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) inhibits the progression of ovarian cancer in coordination with ubiquitin-specific protease 10 (USP10) | Full Text | References | PDF (3.3 MB) | EPUB
  • 1881 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
Carvedilol activates nuclear factor E2-related factor 2/ antioxidant response element pathway to inhibit oxidative stress and apoptosis of retinal pigment epithelial cells induced by high glucose
Yu Zhang, Mingcun Li, Weixing Wang & Siyu He
Pages: 735-745
Published online: 29 Dec 2021
AbstractforCarvedilol activates nuclear factor E2-related factor 2/ antioxidant response element pathway to inhibit oxidative stress and apoptosis of retinal pigment epithelial cells induced by high glucose | Full Text | References | PDF (2.1 MB) | EPUB
  • 1625 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: The long non-coding RNA ASMTL-AS1 promotes hepatocellular carcinoma progression by sponging miR-1343-3p that suppresses LAMC1 (laminin subunit gamma 1)
Yanjie Mou & Qinguo Sun
Pages: 746-758
Published online: 29 Dec 2021
AbstractforRETRACTED ARTICLE: The long non-coding RNA ASMTL-AS1 promotes hepatocellular carcinoma progression by sponging miR-1343-3p that suppresses LAMC1 (laminin subunit gamma 1) | PDF (6.6 MB)
  • 1381 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
New challenges in the use of nanomedicine in cancer therapy
Mahmood Rasool, Arif Malik, Sulayman Waquar, Mahwish Arooj, Sara Zahid, Muhammad Asif, Sumaira Shaheen, Abrar Hussain, Hamid Ullah & Siew Hua Gan
Pages: 759-773
Published online: 04 Jan 2022
AbstractforNew challenges in the use of nanomedicine in cancer therapy | Full Text | References | PDF (1.4 MB) | EPUB
  • 5592 Views
  • 36 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury
Yunguang Wang, Fangfang Feng, Wenfang He, Lifang Sun, Qiang He & Juan Jin
Pages: 774-788
Published online: 05 Jan 2022
AbstractforRETRACTED ARTICLE: miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury | PDF (6.5 MB) | Supplemental
  • 2349 Views
  • 17 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Effect of Taspine hydrochloride on the repair of rat skin wounds by regulating keratinocyte growth factor signal
Xiumei Wang, Yang Gao & Xiaochen Sun
Pages: 789-799
Published online: 30 Dec 2021
AbstractforEffect of Taspine hydrochloride on the repair of rat skin wounds by regulating keratinocyte growth factor signal | Full Text | References | PDF (2.4 MB) | EPUB
  • 1287 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access
Article
Sitagliptin ameliorates hypoxia-induced damages in endometrial stromal cells: an implication in endometriosis
Ying Li, Xiaolin Lv, Mei Jiang & Zhili Jin
Pages: 800-809
Published online: 29 Dec 2021
AbstractforSitagliptin ameliorates hypoxia-induced damages in endometrial stromal cells: an implication in endometriosis | Full Text | References | PDF (1.3 MB) | EPUB
  • 1822 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Circular RNA protein tyrosine kinase 2 (circPTK2) promotes colorectal cancer proliferation, migration, invasion and chemoresistance
Zhipeng Jiang, Zehui Hou, Wei Liu, Zhuomin Yu, Zhiqiang Liang & Shuang Chen
Pages: 810-823
Published online: 03 Jan 2022
AbstractforRETRACTED ARTICLE: Circular RNA protein tyrosine kinase 2 (circPTK2) promotes colorectal cancer proliferation, migration, invasion and chemoresistance | PDF (8.8 MB) | Supplemental
  • 2773 Views
  • 32 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Bone marrow mesenchymal stem cells combined with Atractylodes macrocephala polysaccharide attenuate ulcerative colitis
Zhijuan Zheng & Junqing Wang
Pages: 824-833
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Bone marrow mesenchymal stem cells combined with Atractylodes macrocephala polysaccharide attenuate ulcerative colitis | PDF (4.4 MB)
  • 1807 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Impacts of lipopolysaccharide on fetal lung developmental maturity and surfactant protein B and surfactant protein C protein expression in gestational diabetes mellitus rats
Yue Gao, Ziwei Zhang, Yan Wang, Dayong Zhou, Jinghua Zhang, Xiaoyu Chen, Xin Li & Qingliang Shao
Pages: 834-843
Published online: 09 Jan 2022
AbstractforRETRACTED ARTICLE: Impacts of lipopolysaccharide on fetal lung developmental maturity and surfactant protein B and surfactant protein C protein expression in gestational diabetes mellitus rats | PDF (3.5 MB)
  • 1479 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Upregulation of serum and glucocorticoid-regulated kinase 1 (SGK1) ameliorates doxorubicin-induced cardiotoxic injury, apoptosis, inflammation and oxidative stress by suppressing glucose regulated protein 78 (GRP78)-mediated endoplasmic reticulum stress
Feng Wang & Lili Han
Pages: 844-855
Published online: 30 Dec 2021
AbstractforUpregulation of serum and glucocorticoid-regulated kinase 1 (SGK1) ameliorates doxorubicin-induced cardiotoxic injury, apoptosis, inflammation and oxidative stress by suppressing glucose regulated protein 78 (GRP78)-mediated endoplasmic reticulum stress | Full Text | References | PDF (4.5 MB) | EPUB
  • 1839 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA placenta‑specific protein 2 regulates micorRNA-19a/tumor necrosis factor α to participate in polycystic ovary syndrome
Gang Li, Yongli Wang, Jingyuan Wang, Gong Chen & Haiyan Wang
Pages: 856-862
Published online: 30 Dec 2021
AbstractforRETRACTED ARTICLE: Long non-coding RNA placenta‑specific protein 2 regulates micorRNA-19a/tumor necrosis factor α to participate in polycystic ovary syndrome | PDF (2.8 MB)
  • 1309 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Study on the role and mechanism of lncRNA in the remodeling of atrial energy metabolism in rabbits with atrial fibrillation based on nano sensor technology
Weifeng Jiang, Ming Xu, Mu Qin, Daoliang Zhang, Shaohui Wu, Xu Liu & Yu Zhang
Pages: 863-875
Published online: 30 Dec 2021
AbstractforStudy on the role and mechanism of lncRNA in the remodeling of atrial energy metabolism in rabbits with atrial fibrillation based on nano sensor technology | Full Text | References | PDF (945 KB) | EPUB
  • 1254 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
Paper-based microfluidic chip for rapid detection of SARS-CoV-2 N protein
Mingdi Sun, Man Han, Shengnan Xu, Kai Yan, Gul Nigal, Tongyang Zhang & Bo Song
Pages: 876-883
Published online: 30 Dec 2021
AbstractforPaper-based microfluidic chip for rapid detection of SARS-CoV-2 N protein | Full Text | References | PDF (1 MB) | EPUB
  • 2092 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
Knockdown long non-coding RNA HCP5 enhances the radiosensitivity of esophageal carcinoma by modulating AKT signaling activation
Yue Guo, Lan Wang, Hui Yang & Nannan Ding
Pages: 884-893
Published online: 30 Dec 2021
AbstractforKnockdown long non-coding RNA HCP5 enhances the radiosensitivity of esophageal carcinoma by modulating AKT signaling activation | Full Text | References | PDF (2.2 MB) | EPUB
  • 1215 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
Analysis of abnormal intestinal flora on risk of intestinal cancer and effect of heparin on formation of bacterial biofilm
Qilong Chen, Lin Xu, Tinglun Wu, Jian Li & Li Hua
Pages: 894-904
Published online: 30 Dec 2021
AbstractforAnalysis of abnormal intestinal flora on risk of intestinal cancer and effect of heparin on formation of bacterial biofilm | Full Text | References | PDF (1.1 MB) | EPUB
  • 1413 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access
Article
Extracellular vesicles derived from HBMSCs improved myocardial infarction through inhibiting zinc finger antisense 1 and activating Akt/Nrf2/HO-1 pathway
Huiling Xiao, Dan Wu, Tao Yang, Wei Fu, Lu Yang, Chenkai Hu, Hongbing Wan, Xiaomin Hu, Chenjie Zhang & Tao Wu
Pages: 905-916
Published online: 03 Jan 2022
AbstractforExtracellular vesicles derived from HBMSCs improved myocardial infarction through inhibiting zinc finger antisense 1 and activating Akt/Nrf2/HO-1 pathway | Full Text | References | PDF (4 MB) | EPUB
  • 1630 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
microRNA-20b-5p overexpression combing Pembrolizumab potentiates cancer cells to radiation therapy via repressing programmed death-ligand 1
Kexin Jiang & Huawei Zou
Pages: 917-929
Published online: 30 Dec 2021
AbstractformicroRNA-20b-5p overexpression combing Pembrolizumab potentiates cancer cells to radiation therapy via repressing programmed death-ligand 1 | Full Text | References | PDF (3.6 MB) | EPUB
  • 2744 Views
  • 13 CrossRef citations
  • 0Altmetric
Open Access
Article
Long non-coding RNA myocardial infarction-associated transcript promotes 1-Methyl-4-phenylpyridinium ion-induced neuronal inflammation and oxidative stress in Parkinson’s disease through regulating microRNA-221-3p/ transforming growth factor /nuclear factor E2-related factor 2 axis
Yue Lang, Hui Zhang, Haojia Yu, Yu Li, Xiao Liu & Minjie Li
Pages: 930-940
Published online: 30 Dec 2021
AbstractforLong non-coding RNA myocardial infarction-associated transcript promotes 1-Methyl-4-phenylpyridinium ion-induced neuronal inflammation and oxidative stress in Parkinson’s disease through regulating microRNA-221-3p/ transforming growth factor /nuclear factor E2-related factor 2 axis | Full Text | References | PDF (1.6 MB) | EPUB
  • 1951 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
Relationships between plasma expression levels of microRNA-146a and microRNA-132 in epileptic patients and their cognitive, mental and psychological disorders
Hui Huang, Guiyun Cui, Hai Tang, Lingwen Kong, Xiaopeng Wang, Chenchen Cui, Qihua Xiao & Huiming Ji
Pages: 941-949
Published online: 30 Dec 2021
AbstractforRelationships between plasma expression levels of microRNA-146a and microRNA-132 in epileptic patients and their cognitive, mental and psychological disorders | Full Text | References | PDF (667.2 KB) | EPUB
  • 1333 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
Induction of lncRNA NORAD accounts for hypoxia-induced chemoresistance and vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/ hypoxia-inducible factor-1α (HIF-1α)
Lei Zhang, Huili Wu, Yong Zhang, Xingguo Xiao, Feifei Chu & Li Zhang
Pages: 950-962
Published online: 30 Dec 2021
AbstractforInduction of lncRNA NORAD accounts for hypoxia-induced chemoresistance and vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/ hypoxia-inducible factor-1α (HIF-1α) | Full Text | References | PDF (2.8 MB) | EPUB
  • 2070 Views
  • 14 CrossRef citations
  • 0Altmetric
Open Access
Article
Inhibition of miRNA-100 facilitates bone regeneration defects of mesenchymal stem cells in osteoporotic mice through the protein kinase B pathway
Zhengqiu Dai & Guoqiang Wei
Pages: 963-973
Published online: 08 Feb 2022
AbstractforInhibition of miRNA-100 facilitates bone regeneration defects of mesenchymal stem cells in osteoporotic mice through the protein kinase B pathway | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1303 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA HOXA11 antisense RNA upregulates spermatogenesis-associated serine-rich 2-like to enhance cisplatin resistance in laryngeal squamous cell carcinoma by suppressing microRNA-518a
Na Shen, Xiaohui Duan, Yong Feng, Jianxin Zhang, Xiaocheng Qiao & Wenyu Ding
Pages: 974-984
Published online: 03 Jan 2022
AbstractforRETRACTED ARTICLE: Long non-coding RNA HOXA11 antisense RNA upregulates spermatogenesis-associated serine-rich 2-like to enhance cisplatin resistance in laryngeal squamous cell carcinoma by suppressing microRNA-518a | PDF (6 MB)
  • 1240 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
The protective effects of etomidate against interleukin-1β (IL-1β)-induced oxidative stress, extracellular matrix alteration and cellular senescence in chondrocytes
Miaomiao Yin & Yinmei Xu
Pages: 985-994
Published online: 30 Dec 2021
AbstractforThe protective effects of etomidate against interleukin-1β (IL-1β)-induced oxidative stress, extracellular matrix alteration and cellular senescence in chondrocytes | Full Text | References | PDF (1.5 MB) | EPUB
  • 1826 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
Prostate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen receptors and Fos proto-oncogenes
Xi Hong, Liang Mao, Luwei Xu, Qiang Hu & Ruipeng Jia
Pages: 995-1012
Published online: 03 Jan 2022
AbstractforProstate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen receptors and Fos proto-oncogenes | Full Text | References | PDF (8.5 MB) | EPUB | Supplemental
  • 2388 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
Preparation and characterization of scutellarin loaded on ultradeformable nano-liposomes scutellarin EDTMP (S-UNL-E) and in vitro study of its osteogenesis
Teng Minhua, Wang Dashan, Shi Xinyan, Yuan Xiao, Li Xiaojing & Zhao Baodong
Pages: 1013-1024
Published online: 03 Jan 2022
AbstractforPreparation and characterization of scutellarin loaded on ultradeformable nano-liposomes scutellarin EDTMP (S-UNL-E) and in vitro study of its osteogenesis | Full Text | References | PDF (7.5 MB) | EPUB
  • 1437 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
microRNA-128-3p inhibits CD4+ regulatory T cells enrichment by targeting interleukin 16 in gastric cancer
Weidan Fang, Chao Shi, Yiting Wang, Jianping Song & Ling Zhang
Pages: 1025-1038
Published online: 30 Dec 2021
AbstractformicroRNA-128-3p inhibits CD4+ regulatory T cells enrichment by targeting interleukin 16 in gastric cancer | Full Text | References | PDF (3.1 MB) | EPUB
  • 1900 Views
  • 15 CrossRef citations
  • 0Altmetric
Open Access
Article
Identification and validation of long non-coding RNA associated ceRNAs in intrauterine adhesion
Jingni Zhang, Peng Jiang, Yuan Tu, Ning Li, Yuzhen Huang, Shan Jiang, Wei Kong & Rui Yuan
Pages: 1039-1048
Published online: 30 Dec 2021
AbstractforIdentification and validation of long non-coding RNA associated ceRNAs in intrauterine adhesion | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 2627 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Yin Yang 1 (YY1)-induced long intergenic non-protein coding RNA 472 (LINC00472) aggravates sepsis-associated cardiac dysfunction via the micro-RNA-335-3p (miR-335-3p)/Monoamine oxidase A (MAOA) cascade
Guixi Mo, Jian Mo, Xiujuan Tan, Jingjing Wang, Zhenyi Yan & Yijun Liu
Pages: 1049-1061
Published online: 03 Feb 2022
AbstractforRETRACTED ARTICLE: Yin Yang 1 (YY1)-induced long intergenic non-protein coding RNA 472 (LINC00472) aggravates sepsis-associated cardiac dysfunction via the micro-RNA-335-3p (miR-335-3p)/Monoamine oxidase A (MAOA) cascade | PDF (4.8 MB)
  • 1274 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Propofol induces the apoptosis of neural stem cells via microRNA-9-5p / chemokine CXC receptor 4 signaling pathway
Weixin Zhang, Qi Liu, He Zhu, Chao Ma, Qin Luo, Meilin Ji & Li Liu
Pages: 1062-1072
Published online: 06 Jan 2022
AbstractforPropofol induces the apoptosis of neural stem cells via microRNA-9-5p / chemokine CXC receptor 4 signaling pathway | Full Text | References | PDF (1.5 MB) | EPUB
  • 1267 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
Composting and its application in bioremediation of organic contaminants
Chitsan Lin, Nicholas Kiprotich Cheruiyot, Xuan-Thanh Bui & Huu Hao Ngo
Pages: 1073-1089
Published online: 09 Jan 2022
AbstractforComposting and its application in bioremediation of organic contaminants | Full Text | References | PDF (817.4 KB) | EPUB
  • 6558 Views
  • 29 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
miR-647 inhibits hepatocellular carcinoma cell progression by targeting protein tyrosine phosphatase receptor type F
Xiangyang Ye, Rongxian Qiu, Xiongzhi He, Zhengting Hu, Fengfeng Zheng, Xiaogang Huang, Xuemei Xie, Feihua Chen, Hangbing Ou & Guoxian Lin
Pages: 1090-1102
Published online: 30 Dec 2021
AbstractformiR-647 inhibits hepatocellular carcinoma cell progression by targeting protein tyrosine phosphatase receptor type F | Full Text | References | PDF (3.7 MB) | EPUB
  • 1232 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
DEP domain containing 1B (DEPDC1B) exerts the tumor promoter in hepatocellular carcinoma through activating p53 signaling pathway via kinesin family member 23 (KIF23)
Enhua Shen, Jingzhi Zhang & Yujuan Lu
Pages: 1103-1114
Published online: 05 Jan 2022
AbstractforDEP domain containing 1B (DEPDC1B) exerts the tumor promoter in hepatocellular carcinoma through activating p53 signaling pathway via kinesin family member 23 (KIF23) | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
  • 1455 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
Role of lncRNA LINC01194 in hepatocellular carcinoma via the miR-655-3p/SMAD family member 5 axis
Yang Liu, Jie Liu, Junkai Cui, Ruolei Zhong & Guoyang Sun
Pages: 1115-1125
Published online: 03 Jan 2022
AbstractforRole of lncRNA LINC01194 in hepatocellular carcinoma via the miR-655-3p/SMAD family member 5 axis | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 1338 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
Exogenous H2S reverses high glucose-induced endothelial progenitor cells dysfunction via regulating autophagy
Wenxue Ma, Tingting Zhong, Junqiu Chen, Xiao Ke, Huihua Zuo & Qiang Liu
Pages: 1126-1136
Published online: 04 Jan 2022
AbstractforExogenous H2S reverses high glucose-induced endothelial progenitor cells dysfunction via regulating autophagy | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1762 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
Upregulation of miR-140-5p uncouples mitochondria by targeting Bcl-xL in vascular smooth muscle cells in angiotensin II-induced hypertension
Buxiong Tuo, Jie Xu, Wenqiang Zhang, Xiaomiao Li, Lijing Peng, Qian Zou, Ying Deng, Junning Lei & Hui Li
Pages: 1137-1148
Published online: 04 Jan 2022
AbstractforUpregulation of miR-140-5p uncouples mitochondria by targeting Bcl-xL in vascular smooth muscle cells in angiotensin II-induced hypertension | Full Text | References | PDF (2.1 MB) | EPUB
  • 1341 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
Challenges of pathogen inactivation in animal manure through anaerobic digestion: a short review
Min Lin, Aijie Wang, Lijuan Ren, Wei Qiao, Simon Mdondo Wandera & Renjie Dong
Pages: 1149-1161
Published online: 04 Jan 2022
AbstractforChallenges of pathogen inactivation in animal manure through anaerobic digestion: a short review | Full Text | References | PDF (1.2 MB) | EPUB
  • 3008 Views
  • 18 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
LINC00472 suppresses oral squamous cell carcinoma growth by targeting miR-455-3p/ELF3 axis
Xiu Liu, Xinrong Ma, Hongyu Li, Yu Wang, Minghui Mao, Chao Liang & Ying Hu
Pages: 1162-1173
Published online: 04 Jan 2022
AbstractforLINC00472 suppresses oral squamous cell carcinoma growth by targeting miR-455-3p/ELF3 axis | Full Text | References | PDF (2.1 MB) | EPUB
  • 1488 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Forkhead-box C1 attenuates high glucose-induced trophoblast cell injury during gestational diabetes mellitus via activating adenosine monophosphate-activated protein kinase through regulating fibroblast growth factor 19
Shan Cao & Shuxuan Zhang
Pages: 1174-1184
Published online: 04 Jan 2022
AbstractforRETRACTED ARTICLE: Forkhead-box C1 attenuates high glucose-induced trophoblast cell injury during gestational diabetes mellitus via activating adenosine monophosphate-activated protein kinase through regulating fibroblast growth factor 19 | PDF (6.3 MB)
  • 1398 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Has_circ_0008583 modulates hepatocellular carcinoma progression through the miR-1301-3p/METTL3 pathway
Fenfen Wang, Zhengyuan Xie, Nuobei Zhang, Hao Ding, Kai Xiong, Li Guo, Hongyan Huang & Zhili Wen
Pages: 1185-1197
Published online: 04 Jan 2022
AbstractforRETRACTED ARTICLE: Has_circ_0008583 modulates hepatocellular carcinoma progression through the miR-1301-3p/METTL3 pathway | PDF (7.2 MB) | Supplemental
  • 1709 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Taxifolin improves inflammatory injury of human bronchial epithelial cells by inhibiting matrix metalloproteinase (MMP) 10 via Wnt/β-catenin pathway
Youhua Chen, Yan Mei, Lu Yang, Weibin Li, Yu Zhou, Surong He & Jie Liang
Pages: 1198-1208
Published online: 08 Jan 2022
AbstractforTaxifolin improves inflammatory injury of human bronchial epithelial cells by inhibiting matrix metalloproteinase (MMP) 10 via Wnt/β-catenin pathway | Full Text | References | PDF (2.9 MB) | EPUB
  • 1488 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access
Article
Circular RNA circ-LARP1B contributes to cutaneous squamous cell carcinoma progression by targeting microRNA-515-5p/TPX2 microtubule nucleation factor axis
Lipeng Wang, Shaozhang Hou, Jianning Li, Tian Tian, Rongying Hu & Nan Yu
Pages: 1209-1223
Published online: 04 Jan 2022
AbstractforCircular RNA circ-LARP1B contributes to cutaneous squamous cell carcinoma progression by targeting microRNA-515-5p/TPX2 microtubule nucleation factor axis | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 1417 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
Interleukin-17 promotes proliferation, migration, and invasion of trophoblasts via regulating PPAR-γ/RXR-α/Wnt signaling
Zhuo Zhang, Yuhua Yang, Xiaomei Lv & Hongyuan Liu
Pages: 1224-1234
Published online: 04 Jan 2022
AbstractforInterleukin-17 promotes proliferation, migration, and invasion of trophoblasts via regulating PPAR-γ/RXR-α/Wnt signaling | Full Text | References | PDF (3.3 MB) | EPUB
  • 1938 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
Implementation of novel boolean logic gates for IMPLICATION and XOR functions using riboregulators
Chaoxin Chen, Qi Wu, Qingying Ke, Ting Wang, Yifan Zhang, Feiwen Wei, Xiaolong Wang & Guanglei Liu
Pages: 1235-1248
Published online: 05 Jan 2022
AbstractforImplementation of novel boolean logic gates for IMPLICATION and XOR functions using riboregulators | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 2115 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
A Glimpse of the World of Volatile Fatty Acids Production and Application: A review
Swarnima Agnihotri, Dong-Min Yin, Amir Mahboubi, Tugba Sapmaz, Sunita Varjani, Wei Qiao, Derya Y. Koseoglu-Imer & Mohammad J. Taherzadeh
Pages: 1249-1275
Published online: 06 Jan 2022
AbstractforA Glimpse of the World of Volatile Fatty Acids Production and Application: A review | Full Text | References | PDF (1.7 MB) | EPUB
  • 7005 Views
  • 38 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA 00960 promoted the aggressiveness of lung adenocarcinoma via the miR-124a/SphK1 axis
Zhipeng Ge, Haibo Liu, Tao Ji, Qiaoling Liu, Lulu Zhang, Pengchong Zhu, Liang Li & Liangming Zhu
Pages: 1276-1287
Published online: 09 Jan 2022
AbstractforRETRACTED ARTICLE: Long non-coding RNA 00960 promoted the aggressiveness of lung adenocarcinoma via the miR-124a/SphK1 axis | PDF (6.5 MB)
  • 1372 Views
  • 9 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Circular RNA Plasmacytoma Variant Translocation 1 (CircPVT1) knockdown ameliorates hypoxia-induced bladder fibrosis by regulating the miR-203/Suppressor of Cytokine Signaling 3 (SOCS3) signaling axis
Teng Li, Yi Xing, Guoxian Zhang, Yan Wang, Yinsheng Wei, Lingang Cui, Shaojin Zhang & Qingwei Wang
Pages: 1288-1303
Published online: 09 Jan 2022
AbstractforRETRACTED ARTICLE: Circular RNA Plasmacytoma Variant Translocation 1 (CircPVT1) knockdown ameliorates hypoxia-induced bladder fibrosis by regulating the miR-203/Suppressor of Cytokine Signaling 3 (SOCS3) signaling axis | PDF (6.7 MB)
  • 1511 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Upregulating microRNA-373-3p promotes apoptosis and inhibits metastasis of hepatocellular carcinoma cells
Hongbin Li, Nan Wang, Yuntian Xu, Xiao Chang, Jing Ke & Jun Yin
Pages: 1304-1319
Published online: 05 Jan 2022
AbstractforUpregulating microRNA-373-3p promotes apoptosis and inhibits metastasis of hepatocellular carcinoma cells | Full Text | References | PDF (4.2 MB) | EPUB
  • 1607 Views
  • 11 CrossRef citations
  • 0Altmetric
Open Access

Retracted Article

Article
RETRACTED ARTICLE: Knockdown of forkhead box protein P1 alleviates hypoxia reoxygenation injury in H9c2 cells through regulating Pik3ip1/Akt/eNOS and ROS/mPTP pathway
Xinming Liu, Yixing Yang, Jiawei Song, Dongjie Li, Xiaoyan Liu, Chuang Li, Zheng Ma, Jiuchang Zhong & Lefeng Wang
Pages: 1320-1334
Published online: 08 Jan 2022
AbstractforRETRACTED ARTICLE: Knockdown of forkhead box protein P1 alleviates hypoxia reoxygenation injury in H9c2 cells through regulating Pik3ip1/Akt/eNOS and ROS/mPTP pathway | PDF (6.1 MB)
  • 2027 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Homeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 pathway
Jun Shen, Meng Wang, Fan Li, Huanhuan Yan & Jun Zhou
Pages: 1335-1345
Published online: 05 Jan 2022
AbstractforHomeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 pathway | Full Text | References | PDF (4.1 MB) | EPUB
  • 1233 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
ETS Proto-Oncogene 1-activated muskelin 1 antisense RNA drives the malignant progression of hepatocellular carcinoma by targeting miR-22-3p to upregulate ETS Proto-Oncogene 1
Guozheng Pan, Jian Zhang, Faping You, Tao Cui, Peng Luo, Shuling Wang, Xiaomei Li & Qingzhong Yuan
Pages: 1346-1358
Published online: 05 Jan 2022
AbstractforETS Proto-Oncogene 1-activated muskelin 1 antisense RNA drives the malignant progression of hepatocellular carcinoma by targeting miR-22-3p to upregulate ETS Proto-Oncogene 1 | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 1522 Views
  • 13 CrossRef citations
  • 0Altmetric
Open Access
Article
Long non-coding RNA p53 upregulated regulator of p53 levels (PURPL) promotes the development of gastric cancer
Zhonghua Cheng, Jing Hong, Nan Tang, Fenghua Liu, Shuo Gu & Zhen Feng
Pages: 1359-1376
Published online: 11 Jan 2022
AbstractforLong non-coding RNA p53 upregulated regulator of p53 levels (PURPL) promotes the development of gastric cancer | Full Text | References | PDF (4.4 MB) | EPUB
  • 1445 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling
Feng Yun Yang, Lu Zhang, Yan Zheng & He Dong
Pages: 1377-1387
Published online: 03 Jan 2022
AbstractforRETRACTED ARTICLE: Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling | PDF (5.2 MB)
  • 1536 Views
  • 11 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Up-regulation of caveolin 1 mediated by chitosan activates Wnt/ β-catenin pathway in chronic refractory wound diabetic rat model
Jie Gao, Jiayuan Zhang, Lianheng Xia, Xuewei Liang, Wukun Ding, Meiyu Song, Linggen Li & Zhen Jia
Pages: 1388-1398
Published online: 08 Jan 2022
AbstractforUp-regulation of caveolin 1 mediated by chitosan activates Wnt/ β-catenin pathway in chronic refractory wound diabetic rat model | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 1488 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
The protective effects of dezocine on interleukin-1β-induced inflammation, oxidative stress and apoptosis of human nucleus pulposus cells and the possible mechanisms
Fang Zhu, Wei Duan, Chao Zhong, Bing Ji & Xinjun Liu
Pages: 1399-1410
Published online: 03 Jan 2022
AbstractforThe protective effects of dezocine on interleukin-1β-induced inflammation, oxidative stress and apoptosis of human nucleus pulposus cells and the possible mechanisms | Full Text | References | PDF (2.7 MB) | EPUB
  • 1857 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
Identification of a novel circular RNA circZNF652/miR-486-5p/SERPINE1 signaling cascade that regulates cancer aggressiveness in glioblastoma (GBM)
Liang Liu, Shan Xiao, Yan Wang, Zifeng Zhu, Yiyao Cao, Sen Yang, Rongkang Mai & Yong Zheng
Pages: 1411-1423
Published online: 04 Jan 2022
AbstractforIdentification of a novel circular RNA circZNF652/miR-486-5p/SERPINE1 signaling cascade that regulates cancer aggressiveness in glioblastoma (GBM) | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
  • 1822 Views
  • 11 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA muscleblind like splicing regulator 1 antisense RNA 1 (LncRNA MBNL1-AS1) promotes the progression of acute myocardial infarction by regulating the microRNA-132-3p/SRY-related high-mobility-group box 4 (SOX4) axis
Weifeng Liu, Wenyuan Lin & Liangliang Yu
Pages: 1424-1435
Published online: 03 Jan 2022
AbstractforRETRACTED ARTICLE: Long non-coding RNA muscleblind like splicing regulator 1 antisense RNA 1 (LncRNA MBNL1-AS1) promotes the progression of acute myocardial infarction by regulating the microRNA-132-3p/SRY-related high-mobility-group box 4 (SOX4) axis | PDF (4.6 MB) | Supplemental
  • 1586 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2
Jing Jia, Yueping Wang, Ruijuan Huang, Fengxia Du, Xiaozhu Shen, Qiurong Yang & Juan Li
Pages: 1436-1446
Published online: 05 Jan 2022
AbstractforProtein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2 | Full Text | References | PDF (2.3 MB) | EPUB
  • 1778 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA H19 aggravates keloid progression by upregulating SMAD family member 5 expression via miR-196b-5p
Zhichao Li, Cheng Gong & Huiming Wei
Pages: 1447-1458
Published online: 03 Jan 2022
AbstractforRETRACTED ARTICLE: Long non-coding RNA H19 aggravates keloid progression by upregulating SMAD family member 5 expression via miR-196b-5p | PDF (5.3 MB)
  • 1281 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Exosome-delivered BMP-2 and polyaspartic acid promotes tendon bone healing in rotator cuff tear via Smad/RUNX2 signaling pathway
Lei Han, Hong Liu, Huajun Fu, Yugen Hu, Weili Fang & Junsheng Liu
Pages: 1459-1475
Published online: 04 Jan 2022
AbstractforRETRACTED ARTICLE: Exosome-delivered BMP-2 and polyaspartic acid promotes tendon bone healing in rotator cuff tear via Smad/RUNX2 signaling pathway | PDF (7.9 MB)
  • 3686 Views
  • 21 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Knockdown of hypoxia-inducible factor 1-alpha (HIF1α) interferes with angiopoietin-like protein 2 (ANGPTL2) to attenuate high glucose-triggered hypoxia/reoxygenation injury in cardiomyocytes
Weiguo Chen, Jianbang Wang, Xihui Wang, Pan Chang & Meng Liang
Pages: 1476-1490
Published online: 03 Jan 2022
AbstractforKnockdown of hypoxia-inducible factor 1-alpha (HIF1α) interferes with angiopoietin-like protein 2 (ANGPTL2) to attenuate high glucose-triggered hypoxia/reoxygenation injury in cardiomyocytes | Full Text | References | PDF (3.3 MB) | EPUB
  • 2298 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Repressing phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma by microRNA-142-3p restrains the progression of hepatocellular carcinoma
Chuanli Zeng, Gang Yuan, Yaoren Hu, Donghui Wang, Xiaojun Shi, Dedong Zhu, Airong Hu, Yina Meng & Jialin Lu
Pages: 1491-1506
Published online: 06 Jan 2022
AbstractforRETRACTED ARTICLE: Repressing phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma by microRNA-142-3p restrains the progression of hepatocellular carcinoma | PDF (6.9 MB)
  • 1442 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
LncRNA ASMTL-AS1/microRNA-1270 differentiate prognostic groups in gastric cancer and influence cell proliferation, migration and invasion
Zhenhe Song & Jian Wang
Pages: 1507-1517
Published online: 06 Jan 2022
AbstractforLncRNA ASMTL-AS1/microRNA-1270 differentiate prognostic groups in gastric cancer and influence cell proliferation, migration and invasion | Full Text | References | PDF (883.5 KB) | EPUB
  • 1208 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
Ramelteon protects against human pulmonary microvascular endothelial cell injury induced by lipopolysaccharide (LPS) via activating nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway
Wenjun Yang, Yang Zhang, Dahao Lu, Tianfeng Huang, Keshi Yan, Weiwei Wang & Ju Gao
Pages: 1518-1529
Published online: 06 Jan 2022
AbstractforRamelteon protects against human pulmonary microvascular endothelial cell injury induced by lipopolysaccharide (LPS) via activating nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway | Full Text | References | PDF (3 MB) | EPUB
  • 1900 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Dihydroartemisinin targets fibroblast growth factor receptor 1 (FGFR1) to inhibit interleukin 17A (IL-17A)-induced hyperproliferation and inflammation of keratinocytes
Baojiang Chen, Chen Li, Guizhen Chang & Huan Wang
Pages: 1530-1540
Published online: 10 Jan 2022
AbstractforRETRACTED ARTICLE: Dihydroartemisinin targets fibroblast growth factor receptor 1 (FGFR1) to inhibit interleukin 17A (IL-17A)-induced hyperproliferation and inflammation of keratinocytes | PDF (5.8 MB)
  • 1408 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Trimethylamine N-oxide promotes atherosclerosis via regulating the enriched abundant transcript 1/miR-370-3p/signal transducer and activator of transcription 3/flavin-containing monooxygenase-3 axis
Aijun Liu, Yonglin Zhang, Shucan Xun & Minli Sun
Pages: 1541-1553
Published online: 06 Jan 2022
AbstractforTrimethylamine N-oxide promotes atherosclerosis via regulating the enriched abundant transcript 1/miR-370-3p/signal transducer and activator of transcription 3/flavin-containing monooxygenase-3 axis | Full Text | References | PDF (4.3 MB) | EPUB
  • 1829 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
Long non-coding RNA musculin antisense RNA 1 promotes proliferation and suppresses apoptosis in osteoarthritic chondrocytes via the microRNA-369-3p/Janus kinase-2/ signal transducers and activators of transcription 3 axis
Zhenyu Tang, Zongming Gong & Xiaoliang Sun
Pages: 1554-1564
Published online: 05 Jan 2022
AbstractforLong non-coding RNA musculin antisense RNA 1 promotes proliferation and suppresses apoptosis in osteoarthritic chondrocytes via the microRNA-369-3p/Janus kinase-2/ signal transducers and activators of transcription 3 axis | Full Text | References | PDF (2.1 MB) | EPUB
  • 1364 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts
Jing Li, Yuqing Zou, Song Wang, Shikai Guo, Zhishun Huang & Ran Huo
Pages: 1565-1574
Published online: 06 Jan 2022
AbstractforLong-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts | Full Text | References | PDF (2.1 MB) | EPUB
  • 1468 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Study on the molecular mechanism of nightshade in the treatment of colon cancer
Song Na, Li Ying, Cheng Jun, Xiong Ya, Zhang Suifeng, He Yuxi, Wang Jing, Lai Zonglang, Yang Xiaojun & Wu Yue
Pages: 1575-1589
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: Study on the molecular mechanism of nightshade in the treatment of colon cancer | PDF (8.3 MB)
  • 1869 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Circ_0017639 facilitates proliferative, migratory, and invasive potential of non-small cell lung cancer (NSCLC) cells via PI3K/AKT signaling pathway
Hong-Bo Zhang, Xiang-Ming Qiu, Yi-Chao Zhang, Ting-Ting Huang, Zhan-Jie Zuo & Tao Zhang
Pages: 1590-1601
Published online: 08 Jan 2022
AbstractforRETRACTED ARTICLE: Circ_0017639 facilitates proliferative, migratory, and invasive potential of non-small cell lung cancer (NSCLC) cells via PI3K/AKT signaling pathway | PDF (6.1 MB) | Supplemental
  • 1154 Views
  • 9 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Long non-coding RNA CCL2 promoted gastric cancer function via miR-128/ PARP2 signal pathway
Liang Ma, Yunshan Jiang & Ning Wu
Pages: 1602-1611
Published online: 08 Jan 2022
AbstractforRETRACTED ARTICLE: Long non-coding RNA CCL2 promoted gastric cancer function via miR-128/ PARP2 signal pathway | PDF (4.8 MB)
  • 1385 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Propofol inhibits oxidative stress injury through the glycogen synthase kinase 3 beta/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 signaling pathway
Ziyin Zhang, BaoFeng Yan, Yuguo Li, Shuo Yang & Jinfeng Li
Pages: 1612-1625
Published online: 14 Jan 2022
AbstractforRETRACTED ARTICLE: Propofol inhibits oxidative stress injury through the glycogen synthase kinase 3 beta/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 signaling pathway | PDF (18.6 MB)
  • 1686 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Inhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma
Weiwei Wang, Jianjun Wu, Xulei Dai & Kun Cheng
Pages: 1626-1636
Published online: 08 Jan 2022
AbstractforInhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma | Full Text | References | PDF (3.6 MB) | EPUB
  • 1650 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
lncRNA ZFPM2-AS1 promotes retinoblastoma progression by targeting microRNA miR-511-3p/paired box protein 6 (PAX6) axis
Wenchang Ni, Zhen Li & Kui Ai
Pages: 1637-1649
Published online: 06 Jan 2022
AbstractforlncRNA ZFPM2-AS1 promotes retinoblastoma progression by targeting microRNA miR-511-3p/paired box protein 6 (PAX6) axis | Full Text | References | PDF (6 MB) | EPUB | Supplemental
  • 1178 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: The urinary exosomes derived from premature infants attenuate cisplatin-induced acute kidney injury in mice via microRNA-30a-5p/ mitogen-activated protein kinase 8 (MAPK8)
Mingming Ma, Qiao Luo, Lijing Fan, Weilong Li, Qiang Li, Yu Meng, Chen Yun, Hongwei Wu, Yongping Lu, Shuang Cui, Fanna Liu, Bo Hu, Baozhang Guan, Huanhuan Liu, Shengling Huang, Wenxue Liang, Stanislao Morgera, Bernhard Krämer, Shaodong Luan, Lianghong Yin & Berthold Hocher
Pages: 1650-1665
Published online: 08 Jan 2022
AbstractforRETRACTED ARTICLE: The urinary exosomes derived from premature infants attenuate cisplatin-induced acute kidney injury in mice via microRNA-30a-5p/ mitogen-activated protein kinase 8 (MAPK8) | PDF (6.3 MB)
  • 2095 Views
  • 11 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
DNA methylation across the tree of life, from micro to macro-organism
Nasrullah, Abrar Hussain, Sagheer Ahmed, Mahmood Rasool & Abdul Jabbar Shah
Pages: 1666-1685
Published online: 06 Jan 2022
AbstractforDNA methylation across the tree of life, from micro to macro-organism | Full Text | References | PDF (1.9 MB) | EPUB
  • 3314 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Knockdown of zinc finger protein 267 suppresses diffuse large B-cell lymphoma progression, metastasis, and cancer stem cell properties
Hua Yang, Linmei Wang, Yingbin Zheng, Guiming Hu, Hongyan Ma & Liyun Shen
Pages: 1686-1701
Published online: 08 Jan 2022
AbstractforRETRACTED ARTICLE: Knockdown of zinc finger protein 267 suppresses diffuse large B-cell lymphoma progression, metastasis, and cancer stem cell properties | PDF (8 MB) | Supplemental
  • 1665 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Inhibition of Long non-coding RNA zinc finger antisense 1 improves functional recovery and angiogenesis after focal cerebral ischemia via microRNA-144-5p/fibroblast growth factor 7 axis
Tong Li, Bai Ling Qing, Yan Deng, Xian Ting Que, Cheng Zhi Wang, Hua Wen Lu, Shao Hua Wang & Zi Jun Wang
Pages: 1702-1716
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: Inhibition of Long non-coding RNA zinc finger antisense 1 improves functional recovery and angiogenesis after focal cerebral ischemia via microRNA-144-5p/fibroblast growth factor 7 axis | PDF (5.8 MB) | Supplemental
  • 1345 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Pyroptosis regulators exert crucial functions in prognosis, progression and immune microenvironment of pancreatic adenocarcinoma: a bioinformatic and in vitro research
Zhenghai Bai, Fangshi Xu, Xiaodan Feng, Yuan Wu, Junhua Lv, Yu Shi & Honghong Pei
Pages: 1717-1735
Published online: 08 Jan 2022
AbstractforPyroptosis regulators exert crucial functions in prognosis, progression and immune microenvironment of pancreatic adenocarcinoma: a bioinformatic and in vitro research | Full Text | References | PDF (7.4 MB) | EPUB | Supplemental
  • 2364 Views
  • 9 CrossRef citations
  • 0Altmetric
Open Access
Article
MicroRNA-128-3p suppresses interleukin-1β-stimulated cartilage degradation and chondrocyte apoptosis via targeting zinc finger E-box binding homeobox 1 in osteoarthritis
Yu Sun, Xinnan Bao, Haiou Chen & Liping Zhou
Pages: 1736-1745
Published online: 06 Jan 2022
AbstractforMicroRNA-128-3p suppresses interleukin-1β-stimulated cartilage degradation and chondrocyte apoptosis via targeting zinc finger E-box binding homeobox 1 in osteoarthritis | Full Text | References | PDF (1.7 MB) | EPUB
  • 1288 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
Compatibility of Achyranthes bidentata components in reducing inflammatory response through Arachidonic acid pathway for treatment of Osteoarthritis
Zanzhu Li, Dujun Ma, Liping Peng, Yuan Li, Zhouwei Liao & Tian Yu
Pages: 1746-1757
Published online: 09 Jan 2022
AbstractforCompatibility of Achyranthes bidentata components in reducing inflammatory response through Arachidonic acid pathway for treatment of Osteoarthritis | Full Text | References | PDF (2.3 MB) | EPUB
  • 1900 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Article
IL-35 inhibits cell pyroptosis and attenuates cell injury in TNF-α-induced bronchial epithelial cells via p38 MAPK signaling pathway
Yanbo Wang, Yanling Yu, Wanjing Yu, Xun Bian & Linxia Gong
Pages: 1758-1766
Published online: 16 Jan 2022
AbstractforIL-35 inhibits cell pyroptosis and attenuates cell injury in TNF-α-induced bronchial epithelial cells via p38 MAPK signaling pathway | Full Text | References | PDF (2.8 MB) | EPUB
  • 1726 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Long non-coding RNA taurine up regulated 1 promotes osteosarcoma cell proliferation and invasion through upregulating Ezrin expression as a competing endogenous RNA of micro RNA-377-3p
Qin Yao, Yingchao Li, Yihua Pei & Bozhen Xie
Pages: 1767-1778
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: Long non-coding RNA taurine up regulated 1 promotes osteosarcoma cell proliferation and invasion through upregulating Ezrin expression as a competing endogenous RNA of micro RNA-377-3p | PDF (4.5 MB)
  • 1407 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access

Research paper

Article
Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis
Shan Wang, Xuwen Zha, Shengting Ruan, Shoulin Yao & Xiaoyu Zhang
Pages: 1779-1790
Published online: 11 Jan 2022
AbstractforKruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis | Full Text | References | PDF (2.5 MB) | EPUB
  • 1834 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: MicroRNA-335-5p alleviates inflammatory response, airway fibrosis, and autophagy in childhood asthma through targeted regulation of autophagy related 5
Qingbin Liang, Jingjing He, Qian Yang, Qinghua Zhang & Yingjun Xu
Pages: 1791-1801
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: MicroRNA-335-5p alleviates inflammatory response, airway fibrosis, and autophagy in childhood asthma through targeted regulation of autophagy related 5 | PDF (3.6 MB)
  • 1838 Views
  • 13 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: The protective effects of Olmesartan against interleukin-29 (IL-29)-induced type 2 collagen degradation in human chondrocytes
Yunlong Liu, Junyi Liu, Yan Ma, Yongyong Zhang, Qiong Chen, Xin Yang & Yanchun Shang
Pages: 1802-1813
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: The protective effects of Olmesartan against interleukin-29 (IL-29)-induced type 2 collagen degradation in human chondrocytes | PDF (4.8 MB)
  • 1572 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access
Article
RETRACTED ARTICLE: Circular RNA SOX13 promotes malignant behavior and cisplatin resistance in non-small cell lung cancer through targeting microRNA-3194-3p/microtubule-associated protein RP/EB family member 1
Libin Zhang, Hao Peng, Zheyuan Xu, Qiuju Yang, Yang Wang, Han Wang & Liang Bu
Pages: 1814-1827
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: Circular RNA SOX13 promotes malignant behavior and cisplatin resistance in non-small cell lung cancer through targeting microRNA-3194-3p/microtubule-associated protein RP/EB family member 1 | PDF (6.2 MB)
  • 1635 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Long non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) upregulates Cyclin T2 (CCNT2) in laryngeal papilloma through sponging miR-577/miR-1224-5p and blocking cell apoptosis
Dong Zhao & Yueting Hou
Pages: 1828-1837
Published online: 11 Jan 2022
AbstractforLong non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) upregulates Cyclin T2 (CCNT2) in laryngeal papilloma through sponging miR-577/miR-1224-5p and blocking cell apoptosis | Full Text | References | PDF (1.9 MB) | EPUB
  • 1227 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
LncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells
Deli Tan, Gang Li, Peng Zhang, Chao Peng & Bo He
Pages: 1838-1857
Published online: 11 Jan 2022
AbstractforLncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells | Full Text | References | PDF (5.7 MB) | EPUB
  • 2025 Views
  • 25 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner
You-Qing Miao, Wei Chen, Jianfeng Zhou, Qiyang Shen, Ying Sun, Tao Li & Sheng-Chan Wang
Pages: 1858-1871
Published online: 11 Jan 2022
AbstractforRETRACTED ARTICLE: N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner | PDF (7.2 MB) | Supplemental
  • 1965 Views
  • 15 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Silence of TANK-binding kinase 1 (TBK1) regulates extracellular matrix degradation of chondrocyte in osteoarthritis by janus kinase (JAK)-signal transducer of activators of transcription (STAT) signaling
Peng Sun & Yuan Xue
Pages: 1872-1879
Published online: 07 Feb 2022
AbstractforSilence of TANK-binding kinase 1 (TBK1) regulates extracellular matrix degradation of chondrocyte in osteoarthritis by janus kinase (JAK)-signal transducer of activators of transcription (STAT) signaling | Full Text | References | PDF (1.3 MB) | EPUB
  • 1749 Views
  • 7 CrossRef citations
  • 0Altmetric
Open Access
Article
Melatonin alleviates lipopolysaccharide (LPS) / adenosine triphosphate (ATP)-induced pyroptosis in rat alveolar Type II cells (RLE-6TN) through nuclear factor erythroid 2-related factor 2 (Nrf2)-driven reactive oxygen species (ROS) downregulation
Tao Zhou, Zhaodong Li & Hong Chen
Pages: 1880-1892
Published online: 02 Feb 2022
AbstractforMelatonin alleviates lipopolysaccharide (LPS) / adenosine triphosphate (ATP)-induced pyroptosis in rat alveolar Type II cells (RLE-6TN) through nuclear factor erythroid 2-related factor 2 (Nrf2)-driven reactive oxygen species (ROS) downregulation | Full Text | References | PDF (2.3 MB) | EPUB
  • 1957 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access
Article
High expression of small nucleolar RNA host gene 3 predicts poor prognosis and promotes bone metastasis in prostate cancer by activating transforming growth factor-beta signaling
Xinhua Xi, Zhengbo Hu, Qiang Wu, Konghe Hu, Zhengguo Cao, Jun Zhou, Junjian Liao, Zhipeng Zhang, Yongyu Hu, Xueren Zhong & Yongzheng Bao
Pages: 1895-1907
Published online: 14 Jan 2022
AbstractforHigh expression of small nucleolar RNA host gene 3 predicts poor prognosis and promotes bone metastasis in prostate cancer by activating transforming growth factor-beta signaling | Full Text | References | PDF (3.2 MB) | EPUB
  • 1327 Views
  • 13 CrossRef citations
  • 0Altmetric
Open Access
Article
Inhibition of circular RNA circ_0138959 alleviates pyroptosis of human gingival fibroblasts via the microRNA-527/caspase-5 axis
Jiaxin Pan, Lu Zhao, Jue Liu & Guoyun Wang
Pages: 1908-1920
Published online: 14 Jan 2022
AbstractforInhibition of circular RNA circ_0138959 alleviates pyroptosis of human gingival fibroblasts via the microRNA-527/caspase-5 axis | Full Text | References | PDF (16.6 MB) | EPUB
  • 1611 Views
  • 10 CrossRef citations
  • 0Altmetric
Open Access
Article
Safinamide protects against amyloid β (Aβ)-induced oxidative stress and cellular senescence in M17 neuronal cells
Xunhu Gu, Ge Zhang, Zhengfang Qin, Min Yin, Weiping Chen, Yangbo Zhang & Xu Liu
Pages: 1921-1930
Published online: 09 Jan 2022
AbstractforSafinamide protects against amyloid β (Aβ)-induced oxidative stress and cellular senescence in M17 neuronal cells | Full Text | References | PDF (1.4 MB) | EPUB
  • 1882 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Retraction

Article
RETRACTED ARTICLE: Protein tyrosine phosphatase receptor type Z1 inhibits the cisplatin resistance of ovarian cancer by regulating PI3K/AKT/mTOR signal pathway
Peng Wang, Yuanjing Hu, Pengpeng Qu, Ying Zhao, Jing Liu, Jianguo Zhao & Beihua Kong
Pages: 1931-1941
Published online: 09 Jan 2022
AbstractforRETRACTED ARTICLE: Protein tyrosine phosphatase receptor type Z1 inhibits the cisplatin resistance of ovarian cancer by regulating PI3K/AKT/mTOR signal pathway | PDF (4 MB)
  • 1734 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Retracted Article

Article
RETRACTED ARTICLE: Combination therapy with Nab-paclitaxel and the interleukin-15 fused with anti-human serum albumin nanobody as a synergistic treatment for colorectal cancer
Lipei Wu, Weiwei Wang, Jiale Tian, Chunrun Qi, Zhengxin Cai, Wenhui Yan, Shihai Xuan & Anquan Shang
Pages: 1942-1951
Published online: 12 Jan 2022
AbstractforRETRACTED ARTICLE: Combination therapy with Nab-paclitaxel and the interleukin-15 fused with anti-human serum albumin nanobody as a synergistic treatment for colorectal cancer | PDF (1.9 MB)
  • 3136 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Overexpression of Eukaryotic translation initiation factor 3D induces stem cell-like properties and metastasis in cervix cancer by activating FAK through inhibiting degradation of GRP78
Yan Zhong & Jian Lan
Pages: 1952-1961
Published online: 01 Feb 2022
AbstractforOverexpression of Eukaryotic translation initiation factor 3D induces stem cell-like properties and metastasis in cervix cancer by activating FAK through inhibiting degradation of GRP78 | Full Text | References | PDF (2.9 MB) | EPUB
  • 1392 Views
  • 8 CrossRef citations
  • 0Altmetric
Open Access
Article
Sulforaphane ameliorates amyloid-β-induced inflammatory injury by suppressing the PARP1/SIRT1 pathway in retinal pigment epithelial cells
Song Wang & Yu-jie Tang
Pages: 7079-7089
Published online: 04 Jan 2022
AbstractforSulforaphane ameliorates amyloid-β-induced inflammatory injury by suppressing the PARP1/SIRT1 pathway in retinal pigment epithelial cells | Full Text | References | PDF (3.2 MB) | EPUB
  • 1514 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access

Explore articles

Explore the most recently published articles

Large intestinal nutritional and physicochemical parameters from different dog sizes reshape canine microbiota structure and functions in vitro
Charlotte Deschamps et al.
Article | Published online: 12 Mar 2024
Open Access
Biogenic engineered zinc oxide nanoparticle for sulfur black dye removal from contaminated wastewater: comparative optimization, simulation modeling, and isotherms
Sangita Yadav et al.
Article | Published online: 11 Mar 2024
Open Access
Publisher’s Note
Note | Published online: 1 Mar 2024
Open Access
Publisher’s Note
Note | Published online: 1 Mar 2024
Open Access
View all latest articles