Cell Cycle, Volume 12, Issue 2 (2013)

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Cell Cycle, Volume 12, Issue 2 (2013)

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Editorials: Cell Cycle Features

Article Commentary
“Take it up a NOTCH
” Novel strategies for cancer therapy
Stefanie L. Morgan, Gregory A. Wyant & Daniela M. Dinulescu
Pages: 191-192
Published online: 15 Jan 2012
Citationfor“Take it up a NOTCH | Full Text | References | PDF (232.5 KB)
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Article Commentary
The chains of death
A new view on caspase-8 activation at the DISC
Kolja Schleich, Peter H. Krammer & Inna N. Lavrik
Pages: 193-194
Published online: 15 Jan 2012
CitationforThe chains of death | Full Text | References | PDF (1.4 MB)
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Article Commentary
Essential roles for the nuclear receptor coactivator Ncoa3 in pluripotency
Michelle Percharde & Véronique Azuara
Pages: 195-196
Published online: 15 Jan 2012
CitationforEssential roles for the nuclear receptor coactivator Ncoa3 in pluripotency | Full Text | References | PDF (254 KB)
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Article Commentary
Compensatory β-cell mass expansion
A big role for a tiny actor
Cécile Jacovetti & Romano Regazzi
Pages: 197-198
Published online: 15 Jan 2012
CitationforCompensatory β-cell mass expansion | Full Text | References | PDF (854.9 KB)
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Article Commentary
PI3K-Akt pathway regulates polycomb group protein and stem cell maintenance
Yan Liu, Hao Yu & Stephen D. Nimer
Pages: 199-200
Published online: 15 Jan 2012
CitationforPI3K-Akt pathway regulates polycomb group protein and stem cell maintenance | Full Text | References | PDF (213.2 KB)
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Cell Cycle News & Views

Article Commentary
A novel link between p53 and ROS
Zhaoyue He & Hans-Uwe Simon
Page: 201
Published online: 15 Jan 2012
First Page PreviewforA novel link between p53 and ROS | Full Text | References | PDF (822.2 KB)
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Article Commentary
Linking JNK-STAT3-Akt signaling axis to EZH2 phosphorylation
A novel pathway of carcinogenesis
Yon Rojanasakul
Page: 202
Published online: 15 Jan 2012
First Page PreviewforLinking JNK-STAT3-Akt signaling axis to EZH2 phosphorylation | Full Text | References | PDF (823 KB)
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Article Commentary
p53 continues to surprise
High levels of p53 can suppress apoptosis
David F. Callen
Page: 203
Published online: 15 Jan 2012
First Page Previewforp53 continues to surprise | Full Text | References | PDF (823 KB)
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Article Commentary
Tumors and their stroma
Mitochondria at the crossroad
Paolo Cirri & Paola Chiarugi
Page: 204
Published online: 15 Jan 2012
First Page PreviewforTumors and their stroma | Full Text | References | PDF (823 KB)
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Article Commentary
From photomorphogenesis to cancer
A CSN journey
Leonardo Salmena & Razqallah Hakem
Pages: 205-206
Published online: 15 Jan 2012
First Page PreviewforFrom photomorphogenesis to cancer | Full Text | References | PDF (823.1 KB)
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Extra Views

The mitochondrial H+-ATP synthase and the lipogenic switch
New core components of metabolic reprogramming in induced pluripotent stem (iPS) cells
Alejandro Vazquez-Martin, Bruna Corominas-Faja, Sílvia Cufi, Luciano Vellon, Cristina Oliveras-Ferraros, Octavio J. Menendez, Jorge Joven, Ruth Lupu & Javier A. Menendez
Pages: 207-218
Published online: 15 Jan 2012
AbstractforThe mitochondrial H+-ATP synthase and the lipogenic switch | Full Text | References | PDF (2.6 MB)
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Pharmacological blockade of a β2AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model
Makoto R. Hara, Benjamin D. Sachs, Marc G. Caron & Robert J. Lefkowitz
Pages: 219-224
Published online: 15 Jan 2012
AbstractforPharmacological blockade of a β2AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model | Full Text | References | PDF (1,022.4 KB)
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Perspective

Basal/HER2 breast carcinomas
Integrating molecular taxonomy with cancer stem cell dynamics to predict primary resistance to trastuzumab (Herceptin)
Begoña Martin-Castillo, Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Silvia Cufí, José Manuel Moreno, Bruna Corominas-Faja, Ander Urruticoechea, Ángel G. Martín, Eugeni López-Bonet & Javier A. Menendez
Pages: 225-245
Published online: 15 Jan 2012
AbstractforBasal/HER2 breast carcinomas | Full Text | References | PDF (2.3 MB) | Supplemental
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Review

Review Article
MicroRNA
A third dimension in autophagy
Haiyan Zhai, Andrew Fesler & Jingfang Ju
Pages: 246-250
Published online: 15 Jan 2012
AbstractforMicroRNA | Full Text | References | PDF (1.2 MB)
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Report

Article
Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis
Libor Macurek, Jan Benada, Erik Müllers, Vincentius A. Halim, Kateřina Krejčíková, Kamila Burdová, Sona Pecháčková, Zdeněk Hodný, Arne Lindqvist, René H. Medema & Jiri Bartek
Pages: 251-262
Published online: 15 Jan 2012
AbstractforDownregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis | Full Text | References | PDF (2.5 MB) | Supplemental
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Article
Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene
Jeehae Han, Basil P. Hubbard, Jaehoon Lee, Cristina Montagna, Han-Woong Lee, David A. Sinclair & Yousin Suh
Pages: 263-270
Published online: 15 Jan 2012
AbstractforAnalysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
An Atg10-like E2 enzyme is essential for cell cycle progression but not autophagy in Schizosaccharomyces pombe
Marc D. Flanagan, Simon K. Whitehall & Brian A. Morgan
Pages: 271-277
Published online: 15 Jan 2012
AbstractforAn Atg10-like E2 enzyme is essential for cell cycle progression but not autophagy in Schizosaccharomyces pombe | Full Text | References | PDF (1.8 MB)
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Article
Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9
Jacqueline L.Y. Chee, Suzan Saidin, David P. Lane, Sai Mun Leong, Jacqueline E. Noll, Paul M. Neilsen, Yi Ting Phua, Hani Gabra & Tit Meng Lim
Pages: 278-288
Published online: 15 Jan 2012
AbstractforWild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9 | Full Text | References | PDF (2.5 MB) | Supplemental
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Article
Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism
Implications for breast cancer prevention
Rosa Sanchez-Alvarez, Ubaldo E. Martinez-Outschoorn, Zhao Lin, Rebecca Lamb, James Hulit, Anthony Howell, Federica Sotgia, Emanuel Rubin & Michael P. Lisanti
Pages: 289-301
Published online: 15 Jan 2012
AbstractforEthanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism | Full Text | References | PDF (4.5 MB)
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Article
Diploid, but not haploid, human embryonic stem cells can be derived from microsurgically repaired tripronuclear human zygotes
Yong Fan, Rong Li, Jin Huang, Yang Yu & Jie Qiao
Pages: 302-311
Published online: 15 Jan 2012
AbstractforDiploid, but not haploid, human embryonic stem cells can be derived from microsurgically repaired tripronuclear human zygotes | Full Text | References | PDF (1.8 MB) | Supplemental
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Article
Structural basis for role of ring finger protein RNF168 RING domain
Xiaoqin Zhang, Jie Chen, Minhao Wu, Huakai Wu, Aloysius Wilfred Arokiaraj, Chengliang Wang, Weichang Zhang, Yue Tao, Michael S.Y. Huen & Jianye Zang
Pages: 312-321
Published online: 15 Jan 2012
AbstractforStructural basis for role of ring finger protein RNF168 RING domain | Full Text | References | PDF (3.4 MB) | Supplemental
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Article
Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment
Chen Tian, Guoguang Zheng, Zhipan Cao, Qiao Li, Zhenyu Ju, Jinhong Wang, Weiping Yuan & Tao Cheng
Pages: 322-331
Published online: 15 Jan 2012
AbstractforHes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment | Full Text | References | PDF (2.3 MB)
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Article
Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts
Stephanie L. Smith-Roe, Shivani S. Patel, Yingchun Zhou, Dennis A. Simpson, Shangbang Rao, Joseph G. Ibrahim, Marila Cordeiro-Stone & William K. Kaufmann
Pages: 332-345
Published online: 15 Jan 2012
AbstractforSeparation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts | Full Text | References | PDF (1.9 MB) | Supplemental
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Article
Spermidine promotes mating and fertilization efficiency in model organisms
Maria Anna Bauer, Didac Carmona-Gutiérrez, Christoph Ruckenstuhl, Angela Reisenbichler, Evgenia V. Megalou, Tobias Eisenberg, Christoph Magnes, Helmut Jungwirth, Frank M. Sinner, Thomas R. Pieber, Kai-Uwe Fröhlich, Guido Kroemer, Nektarios Tavernarakis & Frank Madeo
Pages: 346-352
Published online: 15 Jan 2012
AbstractforSpermidine promotes mating and fertilization efficiency in model organisms | Full Text | References | PDF (473.6 KB)
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Article
The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming
Ilaria Marzi, Maria Grazia Cipolleschi, Massimo D'Amico, Theodora Stivarou, Elisabetta Rovida, Maria Cristina Vinci, Silvia Pandolfi, Persio Dello Sbarba, Barbara Stecca & Massimo Olivotto
Pages: 353-364
Published online: 15 Jan 2012
AbstractforThe involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming | Full Text | References | PDF (2.7 MB)
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Article
REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1
Abel Chiu-Shun Chun, Kin-Hang Kok & Dong-Yan Jin
Pages: 365-378
Published online: 15 Jan 2012
AbstractforREV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1 | Full Text | References | PDF (1.6 MB)
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Letter to the Editor

Letter
A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk
Dennis J. Hazelett, Simon G. Coetzee & Gerhard A. Coetzee
Pages: 379-380
Published online: 15 Jan 2012
CitationforA rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk | Full Text | References | PDF (1.3 MB)
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