Acta Oncologica, Volume 47, Issue 4 (2008)

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Acta Oncologica, Volume 47, Issue 4 (2008)

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EDITORIAL

Editorial
DBCG: The Danish Breast Cancer Cooperative Group – a 30-year struggle for better breast cancer treatment in Denmark
Jens Overgaard
Pages: 491-496
Published online: 08 Jul 2009
First Page PreviewforDBCG: The Danish Breast Cancer Cooperative Group – a 30-year struggle for better breast cancer treatment in Denmark | Full Text | References | PDF (68.1 KB)
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Original Article

Article
Danish Breast Cancer Cooperative Group – DBCG: History, organization, and status of scientific achievements at 30-year anniversary
Mogens Blichert-Toft, Peer Christiansen & Henning T. Mouridsen
Pages: 497-505
Published online: 08 Jul 2009
AbstractforDanish Breast Cancer Cooperative Group – DBCG: History, organization, and status of scientific achievements at 30-year anniversary | Full Text | References | PDF (97.5 KB)
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Article
The clinical database and the treatment guidelines of the Danish Breast Cancer Cooperative Group (DBCG); its 30-years experience and future promise
Susanne Møller, Maj-Britt Jensen, Bent Ejlertsen, Karsten D. Bjerre, Martin Larsen, Hanne B. Hansen, Peer Christiansen & Henning T. Mouridsen
Pages: 506-524
Published online: 08 Jul 2009
AbstractforThe clinical database and the treatment guidelines of the Danish Breast Cancer Cooperative Group (DBCG); its 30-years experience and future promise | Full Text | References | PDF (140.9 KB)
  • 3081 Views
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Article
Improvement of prognosis in breast cancer in Denmark 1977–2006, based on the nationwide reporting to the DBCG Registry
Henning T. Mouridsen, Karsten D. Bjerre, Peer Christiansen, Maj-Britt Jensen & Susanne Møller
Pages: 525-536
Published online: 08 Jul 2009
AbstractforImprovement of prognosis in breast cancer in Denmark 1977–2006, based on the nationwide reporting to the DBCG Registry | Full Text | References | PDF (969.1 KB)
  • 872 Views
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Article
Trends in breast cancer during three decades in Denmark: Stage at diagnosis, surgical management and survival
Anni Ravnsbæk Jensen, Anders Husted Madsen & Jens Overgaard
Pages: 537-544
Published online: 08 Jul 2009
AbstractforTrends in breast cancer during three decades in Denmark: Stage at diagnosis, surgical management and survival | Full Text | References | PDF (69.1 KB)
  • 945 Views
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Article
Pregnancy after treatment of breast cancer – A population-based study on behalf of Danish Breast Cancer Cooperative Group
Niels Kroman, Maj-Britt Jensen, Jan Wohlfahrt & Bent Ejlertsen
Pages: 545-549
Published online: 08 Jul 2009
AbstractforPregnancy after treatment of breast cancer – A population-based study on behalf of Danish Breast Cancer Cooperative Group | Full Text | References | PDF (58 KB)
  • 2868 Views
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Article
Participation behaviour following a false positive test in the Copenhagen mammography screening programme
Sune Bangsbøll Andersen, Ilse Vejborg & My von Euler-Chelpin
Pages: 550-555
Published online: 08 Jul 2009
AbstractforParticipation behaviour following a false positive test in the Copenhagen mammography screening programme | Full Text | References | PDF (62.9 KB)
  • 1232 Views
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Article
Organized nation-wide implementation of sentinel lymph node biopsy in Denmark
Esbern Friis, Hanne Galatius & Jens Peter Garne
Pages: 556-560
Published online: 08 Jul 2009
AbstractforOrganized nation-wide implementation of sentinel lymph node biopsy in Denmark | Full Text | References | PDF (71 KB)
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Article
Sentinel node biopsy in breast cancer: Five years experience from Denmark
Peer Christiansen, Esbern Friis, Eva Balslev, Disa Jensen & Susanne Møller
Pages: 561-568
Published online: 08 Jul 2009
AbstractforSentinel node biopsy in breast cancer: Five years experience from Denmark | Full Text | References | PDF (82 KB)
  • 841 Views
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Article
Shoulder disability and late symptoms following surgery for early breast cancer
Mette Cathrine Lauridsen, Marie Overgaard, Jens Overgaard, I. B. Hessov & Peer Cristiansen
Pages: 569-575
Published online: 08 Jul 2009
AbstractforShoulder disability and late symptoms following surgery for early breast cancer | Full Text | References | PDF (68.5 KB)
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Review Article

Review Article
Timing of breast cancer surgery in relation to the menstrual cycle – The rise and fall of a hypothesis
Niels Kroman
Pages: 576-579
Published online: 08 Jul 2009
AbstractforTiming of breast cancer surgery in relation to the menstrual cycle – The rise and fall of a hypothesis | Full Text | References | PDF (48.5 KB)
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Review Article
TIMP-1 as a tumor marker in breast cancer – An update
Sidse Ø Würtz, Sidse Ø Würtz, Anne-Sofie Schrohl, Henning Mouridsen & Nils Brünner
Pages: 580-590
Published online: 08 Jul 2009
AbstractforTIMP-1 as a tumor marker in breast cancer – An update | Full Text | References | PDF (218.8 KB)
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Original Article

Article
Tissue microarrays compared with whole sections and biochemical analyses. A subgroup analysis of DBCG 82 b&c.
M. Kyndi, F. B. Sørensen, H. Knudsen, M. Overgaard, H. M. Nielsen, J. Andersen & J. Overgaard
Pages: 591-599
Published online: 08 Jul 2009
AbstractforTissue microarrays compared with whole sections and biochemical analyses. A subgroup analysis of DBCG 82 b&c. | Full Text | References | PDF (103.9 KB)
  • 1867 Views
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Article
A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients
Jan Alsner, Vibeke Jensen, Marianne Kyndi, Birgitte Vrou Offersen, Phuong Vu, Anne-Lise Børresen-Dale & Jens Overgaard
Pages: 600-607
Published online: 08 Jul 2009
AbstractforA comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients | Full Text | References | PDF (100.6 KB)
  • 2243 Views
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Article
Impact of BCL2 and p53 on postmastectomy radiotherapy response in high-risk breast cancer. A subgroup analysis of DBCG82 b&c
M. Kyndi, F. B. Sørensen, H. Knudsen, J. Alsner, M. Overgaard, H. M. Nielsen & J. Overgaard
Pages: 608-617
Published online: 08 Jul 2009
AbstractforImpact of BCL2 and p53 on postmastectomy radiotherapy response in high-risk breast cancer. A subgroup analysis of DBCG82 b&c | Full Text | References | PDF (113.6 KB)
  • 871 Views
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Article
A comparison among HER2, TP53, PAI-1, angiogenesis, and proliferation activity as prognostic variables in tumours from 408 patients diagnosed with early breast cancer
Birgitte Vrou Offersen, Jan Alsner, Karen Ege Olsen, Rikke Riisbro, Nils Brünner, Flemming Brandt Sørensen, Boe Sandahl Sørensen, Birgitte Olrik Schlemmer, Jens Overgaard & (on behalf of the DBCG Translational Research Committee)
Pages: 618-632
Published online: 08 Jul 2009
AbstractforA comparison among HER2, TP53, PAI-1, angiogenesis, and proliferation activity as prognostic variables in tumours from 408 patients diagnosed with early breast cancer | Full Text | References | PDF (126.5 KB)
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Article
Extended radical mastectomy versus simple mastectomy followed by radiotherapy in primary breast cancer. A fifty-year follow-up to the Copenhagen Breast Cancer randomised study
Helge Johansen, Sigvard Kaae, Helge Johansen, Sigvard Kaae, Maj-Britt Jensen & Henning T. Mouridsen
Pages: 633-638
Published online: 08 Jul 2009
AbstractforExtended radical mastectomy versus simple mastectomy followed by radiotherapy in primary breast cancer. A fifty-year follow-up to the Copenhagen Breast Cancer randomised study | Full Text | References | PDF (98.6 KB)
  • 1460 Views
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Article
Postoperative radiotherapy in DBCG during 30 years. Techniques, indications and clinical radiobiological experience
Marie Overgaard & Jens Juul Christensen
Pages: 639-653
Published online: 08 Jul 2009
AbstractforPostoperative radiotherapy in DBCG during 30 years. Techniques, indications and clinical radiobiological experience | Full Text | References | PDF (472.1 KB)
  • 1368 Views
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Article
Post-mastectomy radiotherapy in Denmark: From 2D to 3D treatment planning guidelines of The Danish Breast Cancer Cooperative Group
Mette S. Thomsen, Martin Berg, Hanne M. Nielsen, Aanders N. Pedersen, Marie Overgaard, Marianne Ewertz, Thomas Block, Hans J. Brodersen, Claudio Caldera, Erik Jakobsen, Claus Kamby, Flemming Kjær-Kristoffersen, Dorte Klitgaard, Mette M. Nielsen, Lars Stenbygaard, Sune J. Zimmermann & Cai Grau
Pages: 654-661
Published online: 08 Jul 2009
AbstractforPost-mastectomy radiotherapy in Denmark: From 2D to 3D treatment planning guidelines of The Danish Breast Cancer Cooperative Group | Full Text | References | PDF (221.1 KB)
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Article
Adjuvant cyclophosphamide, methotrexate, and fluorouracil in premonopausal patients with node-positive breast cancer: Indirect comparison of dose and schedule in DBCG trials 77, 82, and 89
Bent Ejlertsen, Henning T. Mouridsen & Maj-Britt Jensen
Pages: 662-671
Published online: 08 Jul 2009
AbstractforAdjuvant cyclophosphamide, methotrexate, and fluorouracil in premonopausal patients with node-positive breast cancer: Indirect comparison of dose and schedule in DBCG trials 77, 82, and 89 | Full Text | References | PDF (220.3 KB)
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Article
Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized DBCG-82TM protocol
Mogens Blichert-Toft, Maja Nielsen, Maria Düring, Susanne Møller, Fritz Rank, Marie Overgaard & Henning T. Mouridsen
Pages: 672-681
Published online: 08 Jul 2009
AbstractforLong-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized DBCG-82TM protocol | Full Text | References | PDF (105.8 KB)
  • 6756 Views
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Article
Breast conserving treatment in Denmark, 1989–1998. A nationwide population-based study of the Danish Breast Cancer Co-operative Group.
Marianne Ewertz, Mette Moe Kempel, Maria Düring, Maj-Britt Jensen, Michael Andersson, Peer Christiansen, Niels Kroman, Birgitte Bruun Rasmussen & Marie Overgaard
Pages: 682-690
Published online: 08 Jul 2009
AbstractforBreast conserving treatment in Denmark, 1989–1998. A nationwide population-based study of the Danish Breast Cancer Co-operative Group. | Full Text | References | PDF (206.7 KB)
  • 730 Views
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Article
Recurrence pattern and prognosis in low-risk breast cancer patients – Data from the DBCG 89-A programme
Peer Christiansen, Nidal Al-Suliman, Karsten Bjerre & Susanne Møller
Pages: 691-703
Published online: 08 Jul 2009
AbstractforRecurrence pattern and prognosis in low-risk breast cancer patients – Data from the DBCG 89-A programme | Full Text | References | PDF (193.1 KB)
  • 1774 Views
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Article
Long-term outcome after mastectomy with immediate breast reconstruction
Kristina Strålman, Charlotte L. Mollerup, Ulrik S. Kristoffersen & Jens J. Elberg
Pages: 704-708
Published online: 08 Jul 2009
AbstractforLong-term outcome after mastectomy with immediate breast reconstruction | Full Text | References | PDF (107.5 KB)
  • 1538 Views
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Article
DBCG trial 89B comparing adjuvant CMF and ovarian ablation: Similar outcome for eligible but non-enrolled and randomized breast cancer patients
Bent Ejlertsen, Maj-Britt Jensen, Henning T. Mouridsen, Jørn Andersen, Søren Cold, Erik Jakobsen, Claus Kamby, Peter G. Sørensen & Marianne Ewertz
Pages: 709-717
Published online: 08 Jul 2009
AbstractforDBCG trial 89B comparing adjuvant CMF and ovarian ablation: Similar outcome for eligible but non-enrolled and randomized breast cancer patients | Full Text | References | PDF (109.8 KB)
  • 847 Views
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Article
Tamoxifen for one year versus two years versus 6 months of Tamoxifen and 6 months of megestrol acetate: A randomized comparison in postmenopausal patients with high-risk breast cancer (DBCG 89C)
Jørn Andersen, Claus Kamby, Bent Ejlertsen, Søren Cold, Marianne Ewertz, Erik H. Jacobsen, Preben Philip, Knud A. Møller, Disa Jensen & Susanne Møller
Pages: 718-724
Published online: 08 Jul 2009
AbstractforTamoxifen for one year versus two years versus 6 months of Tamoxifen and 6 months of megestrol acetate: A randomized comparison in postmenopausal patients with high-risk breast cancer (DBCG 89C) | Full Text | References | PDF (84.1 KB)
  • 2288 Views
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Article
The value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D
Kirsten Vang Nielsen, Bent Ejlertsen, Susanne Møller, Jan Trøst Jørgensen, Ann Knoop, Helle Knudsen & Henning T. Mouridsen
Pages: 725-734
Published online: 16 Sep 2009
AbstractforThe value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D | Full Text | References | PDF (245.2 KB)
  • 1957 Views
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Article
Vinorelbine as first-line or second-line therapy for advanced breast cancer: A Phase I-II trial by the Danish Breast Cancer Co-operative Group
Sven T. Langkjer, Bent Ejlertsen, Henning Mouridsen, Jørn Andersen, Mette Møller Nielsen, Knud Åge Møller, Ebbe Lindegaard Madsen & Vera Haarh
Pages: 735-739
Published online: 08 Jul 2009
AbstractforVinorelbine as first-line or second-line therapy for advanced breast cancer: A Phase I-II trial by the Danish Breast Cancer Co-operative Group | Full Text | References | PDF (71.9 KB)
  • 1050 Views
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Article
Bisphosphonate treatment in primary breast cancer: Results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer
Bent Kristensen, Bent Ejlertsen, Henning T. Mouridsen, Maj-Britt Jensen, Jørn Andersen, Brita Bjerregaard, Søren Cold, Per Edlund, Marianne Ewertz, Claus Kamby, Henrik Lindman, Bo Nordenskjöld & Jonas Bergh
Pages: 740-746
Published online: 08 Jul 2009
AbstractforBisphosphonate treatment in primary breast cancer: Results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer | Full Text | References | PDF (160.6 KB)
  • 1830 Views
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REVIEW ARTICLE

Review Article
Adverse bone effects during pharmacological breast cancer therapy
Nina H. Bjarnason, Mette Hitz, Niklas R. Jorgensen, Peter Vestergaard & (on behalf of the board of Danish Bone Society)
Pages: 747-754
Published online: 08 Jul 2009
AbstractforAdverse bone effects during pharmacological breast cancer therapy | Full Text | References | PDF (79.1 KB)
  • 2411 Views
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Original Article

Article
Risk of second primary cancer among patients with early operable breast cancer registered or randomised in Danish Breast Cancer cooperative Group (DBCG) protocols of the 77, 82 and 89 programmes during 1977–2001
Michael Andersson, Maj-Britt Jensen, Gerda Engholm & Hans Henrik Storm
Pages: 755-764
Published online: 08 Jul 2009
AbstractforRisk of second primary cancer among patients with early operable breast cancer registered or randomised in Danish Breast Cancer cooperative Group (DBCG) protocols of the 77, 82 and 89 programmes during 1977–2001 | Full Text | References | PDF (82.3 KB)
  • 1863 Views
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Article
Breast cancer in situ. From pre-malignant lesion of uncertain significance to well-defined non-invasive malignant lesion. The Danish Breast Cancer Cooperative Group Register 1977–2007 revisited
Anne-Vibeke Lænkholm, Maj-Britt Jensen, Niels Kroman & Fritz Rank
Pages: 765-771
Published online: 08 Jul 2009
AbstractforBreast cancer in situ. From pre-malignant lesion of uncertain significance to well-defined non-invasive malignant lesion. The Danish Breast Cancer Cooperative Group Register 1977–2007 revisited | Full Text | References | PDF (334.8 KB)
  • 820 Views
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Article
BRCA1 and BRCA2 mutations in Danish families with hereditary breast and/or ovarian cancer
Mads Thomassen, Thomas V. O. Hansen, Åke Borg, Henriette Theilmann Lianee, Friedrik Wikman, Inge Søkilde Pedersen, Marie Luise Bisgaard, Finn C. Nielsen, Torben A. Kruse & Anne-Marie Gerdes
Pages: 772-777
Published online: 08 Jul 2009
AbstractforBRCA1 and BRCA2 mutations in Danish families with hereditary breast and/or ovarian cancer | Full Text | References | PDF (69.1 KB)
  • 3176 Views
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Article
Classical pathological variables recorded in the Danish Breast Cancer Cooperative Group's register 1978–2006
Henrik W. Kiaer, Anne-Vibeke Laenkholm, Bernt B. Nielsen & Karsten D. Bjerre
Pages: 778-783
Published online: 08 Jul 2009
AbstractforClassical pathological variables recorded in the Danish Breast Cancer Cooperative Group's register 1978–2006 | Full Text | References | PDF (88.1 KB)
  • 567 Views
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Article
Evaluation of and quality assurance in HER2 analysis in breast carcinomas from patients registered in Danish Breast Cancer Group (DBCG) in the period of 2002–2006. A nationwide study including correlation between HER-2 status and other prognostic variables
Birgitte Bruun Rasmussen, Michael Andersson, Ib J. Christensen & Susanne Møller
Pages: 784-788
Published online: 08 Jul 2009
AbstractforEvaluation of and quality assurance in HER2 analysis in breast carcinomas from patients registered in Danish Breast Cancer Group (DBCG) in the period of 2002–2006. A nationwide study including correlation between HER-2 status and other prognostic variables | Full Text | References | PDF (59.7 KB)
  • 601 Views
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Article
Estrogen Receptor analyses in the Danish Breast Cancer Cooperative Group. History, methods, prognosis and clinical implications
Maj-Lis M. Talman, Birgitte B. Rasmussen, Jørn Andersen & Ib J. Christensen
Pages: 789-794
Published online: 08 Jul 2009
AbstractforEstrogen Receptor analyses in the Danish Breast Cancer Cooperative Group. History, methods, prognosis and clinical implications | Full Text | References | PDF (144.8 KB)
  • 648 Views
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REVIEW ARTICLE

Review Article
Development of new predictive markers for endocrine therapy and resistance in breast cancer
Katrine L. Henriksen, Katrine Sonne-Hansen, Tove Kirkegaard, Thomas Frogne & Anne E. Lykkesfeldt
Pages: 795-801
Published online: 08 Jul 2009
AbstractforDevelopment of new predictive markers for endocrine therapy and resistance in breast cancer | Full Text | References | PDF (296.3 KB)
  • 821 Views
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