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Research Article

Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia

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Pages 267-294 | Published online: 09 Jul 2009

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Tang Chendian, Huang Guohua, Zhibiao Wang, Liu Fang, Shuang Luo, Xiaofang Liu & Qiuling Shi. (2024) Factors associated with thermal injury of abdominal skin in focused ultrasound ablation of uterine fibroids. International Journal of Hyperthermia 41:1.
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Jing Li, Yanyong Ye, Zixin Lin, Zhe Wang, Yuxun Chen, Gang Li, Zhi Ouyang & Jing Li. (2023) Application of a new self-regulating temperature magnetic material Fe83Zr10B7 in magnetic induction hyperthermia. International Journal of Hyperthermia 40:1.
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Iris S. G. Brummelhuis, Johannes Crezee & J. Alfred Witjes. (2023) Evaluation of thermal dose effect in radiofrequency-induced hyperthermia with intravesical chemotherapy for nonmuscle invasive bladder cancer. International Journal of Hyperthermia 40:1.
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Zheng Wei, Ziwei Zhang, Xianxuan Feng, Yun Cai, Jiajia Yang, Zikai Hua, Yuehong Bai & Yiming Xu. (2023) Sol-gel dip-coated TiO2 nanofilms reduce heat production in titanium alloy implants produced by microwave diathermy. International Journal of Hyperthermia 40:1.
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H. T. I. Assi, M. G. Arsenault, W. M. Whelan & J. C. Kumaradas. (2022) A new thermal dose model based on Vogel-Tammann-Fulcher behaviour in thermal damage processes. International Journal of Hyperthermia 39:1, pages 697-705.
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Tashmeen Kaur & Deepika Sharma. (2022) Expansion of Thermometry in Magnetic Hyperthermia Cancer Therapy: Antecedence and Aftermath. Nanomedicine 17:21, pages 1607-1623.
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Julian Palzer, Benedikt Mues, Richard Goerg, Merel Aberle, Sander S Rensen, Steven W M Olde Damink, Rianne D W Vaes, Thorsten Cramer, Thomas Schmitz-Rode, Ulf P Neumann, Ioana Slabu & Anjali A Roeth. (2021) Magnetic Fluid Hyperthermia as Treatment Option for Pancreatic Cancer Cells and Pancreatic Cancer Organoids. International Journal of Nanomedicine 16, pages 2965-2981.
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Motohiro Kawasaki, Shudai Muramatsu, Hirofumi Namba, Masashi Izumi, Masahiko Ikeuchi, Shin Yaogawa, Kazuo Morio & Takahiro Ushida. (2021) Efficacy and safety of magnetic resonance-guided focused ultrasound treatment for refractory chronic pain of medial knee osteoarthritis. International Journal of Hyperthermia 38:2, pages 46-55.
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Petros X. E. Mouratidis & Gail ter Haar. (2021) HSP90 inhibition acts synergistically with heat to induce a pro-immunogenic form of cell death in colon cancer cells. International Journal of Hyperthermia 38:1, pages 1443-1456.
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Irene Rubia-Rodríguez, Luca Zilberti, Alessandro Arduino, Oriano Bottauscio, Mario Chiampi & Daniel Ortega. (2021) In silico assessment of collateral eddy current heating in biocompatible implants subjected to magnetic hyperthermia treatments. International Journal of Hyperthermia 38:1, pages 846-861.
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Jacek Nadobny, Amanda Lim, Georg Seifert, Dennis Sullivan, Benjamin Chrzon, Mirko Weihrauch, Sebastian Zschaeck, Enrico Herz, Aleksandra Moczynska, Ruben Pellicer-Guridi, Peter Wust, Marcus Beck & Pirus Ghadjar. (2021) Improved patient-specific hyperthermia planning based on parametrized electromagnetic and thermal models for the SIGMA-30 applicator. International Journal of Hyperthermia 38:1, pages 663-678.
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Bryce McCarthy, Ravi Singh & Nicole Levi-Polyachenko. (2021) Oxaliplatin-resistant colorectal cancer models for nanoparticle hyperthermia. International Journal of Hyperthermia 38:1, pages 152-164.
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Niloy R. Datta, Dietmar Marder, Sneha Datta, Andreas Meister, Emsad Puric, Emanuel Stutz, Susanne Rogers, Brigitte Eberle, Olaf Timm, Michal Staruch, Oliver Riesterer & Stephan Bodis. (2021) Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature–time area under the curve (AUC). International Journal of Hyperthermia 38:1, pages 296-307.
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Harley F. Rodrigues, Gustavo Capistrano & Andris F. Bakuzis. (2020) In vivo magnetic nanoparticle hyperthermia: a review on preclinical studies, low-field nano-heaters, noninvasive thermometry and computer simulations for treatment planning. International Journal of Hyperthermia 37:3, pages 76-99.
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Ethan S. Srinivasan, Eric W. Sankey, Matthew M. Grabowski, Pakawat Chongsathidkiet & Peter E. Fecci. (2020) The intersection between immunotherapy and laser interstitial thermal therapy: a multipronged future of neuro-oncology. International Journal of Hyperthermia 37:2, pages 27-34.
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Kayla E. A. Duval, James D. Petryk, Margaret A. Crary-Burney, Eugene Demidenko, Robert J. Wagner & P. Jack Hoopes. (2020) mNP hyperthermia and hypofractionated radiation activate similar immunogenetic and cytotoxic pathways. International Journal of Hyperthermia 37:1, pages 929-937.
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Helmut Piazena, Werner Müller & Peter Vaupel. (2020) wIRA-heating of piglet skin and subcutis in vivo: proof of accordance with ESHO criteria for superficial hyperthermia. International Journal of Hyperthermia 37:1, pages 887-896.
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Lukas Christian Sebeke, Pia Rademann, Alexandra Claudia Maul, Claudia Schubert-Quecke, Thorsten Annecke, Sin Yuin Yeo, Juan Daniel Castillo-Gómez, Patrick Schmidt, Holger Grüll & Edwin Heijman. (2020) Feasibility study of MR-guided pancreas ablation using high-intensity focused ultrasound in a healthy swine model. International Journal of Hyperthermia 37:1, pages 786-798.
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H. Petra Kok, Erik N. K. Cressman, Wim Ceelen, Christopher L. Brace, Robert Ivkov, Holger Grüll, Gail ter Haar, Peter Wust & Johannes Crezee. (2020) Heating technology for malignant tumors: a review. International Journal of Hyperthermia 37:1, pages 711-741.
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D. Labavić, M. T. Ladjimi, E. Courtade, B. Pfeuty & Q. Thommen. (2020) Mammalian cell sensitivity to hyperthermia in various cell lines: a new universal and predictive description. International Journal of Hyperthermia 37:1, pages 506-516.
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Pierre Agnass, Eran van Veldhuisen, Martin J. C. van Gemert, Cees W. M. van der Geld, Krijn P. van Lienden, Thomas M. van Gulik, Martijn R. Meijerink, Marc G. Besselink, H. Petra Kok & Johannes Crezee. (2020) Mathematical modeling of the thermal effects of irreversible electroporation for in vitro, in vivo, and clinical use: a systematic review. International Journal of Hyperthermia 37:1, pages 486-505.
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Anirudh Sharma, Michelle A. Rudek, Preethi Korangath, Fred Bunz & Robert Ivkov. (2020) For HIPEC, synergistic effects of hyperthermia and doxorubicin are optimal when simultaneously combined. International Journal of Hyperthermia 37:1, pages 346-348.
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Layla Alumutairi, Bing Yu, Mitchell Filka, Joseph Nayfach & Min-Ho Kim. (2020) Mild magnetic nanoparticle hyperthermia enhances the susceptibility of Staphylococcus aureus biofilm to antibiotics. International Journal of Hyperthermia 37:1, pages 66-75.
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Anilchandra Attaluri, John Jackowski, Anirudh Sharma, Sri Kamal Kandala, Valentin Nemkov, Chris Yakey, Theodore L. DeWeese, Ananda Kumar, Robert C. Goldstein & Robert Ivkov. (2020) Design and construction of a Maxwell-type induction coil for magnetic nanoparticle hyperthermia. International Journal of Hyperthermia 37:1, pages 1-14.
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Mark D. Hurwitz. (2019) Hyperthermia and immunotherapy: clinical opportunities. International Journal of Hyperthermia 36:sup1, pages 4-9.
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Sanjeev Soni & Ravindra K Sinha. (2019) Tumor Blood Perfusion-Based Requirement of Nanoparticle Dose-Loadings for Plasmonic Photothermal Therapy. Nanomedicine 14:14, pages 1841-1855.
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Dong Liu, Matthew S. Adams & Chris J. Diederich. (2019) Endobronchial high-intensity ultrasound for thermal therapy of pulmonary malignancies: simulations with patient-specific lung models. International Journal of Hyperthermia 36:1, pages 1107-1120.
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Akke Bakker, Jacoba van der Zee, Geertjan van Tienhoven, H. Petra Kok, Coen R. N. Rasch & Hans Crezee. (2019) Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review. International Journal of Hyperthermia 36:1, pages 1023-1038.
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Mikael Anttinen, Eemil Yli-Pietilä, Visa Suomi, Pietari Mäkelä, Teija Sainio, Jani Saunavaara, Lauri Eklund, Roberto Blanco Sequeiros, Pekka Taimen & Peter J. Boström. (2019) Histopathological evaluation of prostate specimens after thermal ablation may be confounded by the presence of thermally-fixed cells. International Journal of Hyperthermia 36:1, pages 914-924.
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Fenggang Ren, Qingshan Li, Xuyao Gao, Kun Zhu, Jing Zhang, Xue Chen, Xiaopeng Yan, Dake Chu, Liangshuo Hu, Zhongquan Gao, Zheng Wu, Rongqian Wu & Yi Lv. (2019) Electrical and thermal analyses of catheter-based irreversible electroporation of digestive tract. International Journal of Hyperthermia 36:1, pages 853-866.
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Samuel John Fahrenholtz, Chunxiao Guo, Christopher J. MacLellan, Joshua P. Yung, Ken-Pin Hwang, Rick R. Layman, R. Jason Stafford & Erik Cressman. (2019) Temperature mapping of exothermic in situ chemistry: imaging of thermoembolization via MR. International Journal of Hyperthermia 36:1, pages 729-737.
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M. T. Ladjimi, D. Labavić, M. Guilbert, F. Anquez, A. Pruvost, E. Courtade, B. Pfeuty & Q. Thommen. (2019) Dynamical thermal dose models and dose time-profile effects. International Journal of Hyperthermia 36:1, pages 720-728.
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Anirudh Sharma, Sanem Özayral, Julia S. Caserto, Rosemarie ten Cate, Nicole M. Anders, James D. Barnett, Sri Kamal Kandala, Elizabeth Henderson, Jacqueline Stewart, Eleni Liapi, Michelle A. Rudek, Nicolaas A.P. Franken, Arlene L. Oei, Preethi Korangath, Fred Bunz & Robert Ivkov. (2019) Increased uptake of doxorubicin by cells undergoing heat stress does not explain its synergistic cytotoxicity with hyperthermia. International Journal of Hyperthermia 36:1, pages 711-719.
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Petros X. E. Mouratidis, Ian Rivens, John Civale, Richard Symonds-Tayler & Gail ter Haar. (2019) ‘Relationship between thermal dose and cell death for “rapid” ablative and “slow” hyperthermic heating’. International Journal of Hyperthermia 36:1, pages 228-242.
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Sri Kamal Kandala, Eleni Liapi, Louis L. Whitcomb, Anilchandra Attaluri & Robert Ivkov. (2019) Temperature-controlled power modulation compensates for heterogeneous nanoparticle distributions: a computational optimization analysis for magnetic hyperthermia. International Journal of Hyperthermia 36:1, pages 115-129.
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Chang-Soon Lee, Jae Young Lee, Soohan Ro, Seungeun Choi & Jee Youn Moon. (2018) Comparison of effectiveness of epidural analgesia and monitored anesthesia care for high-intensity focused ultrasound treatment of adenomyosis. International Journal of Hyperthermia 35:1, pages 617-625.
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Marion C. Seward, Gregory B. Daniel, Jeffrey D. Ruth, Nikolaos Dervisis, Ari Partanen & Pavel S. Yarmolenko. (2018) Feasibility of targeting canine soft tissue sarcoma with MR-guided high-intensity focused ultrasound. International Journal of Hyperthermia 35:1, pages 205-215.
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Dong Liu, Matthew S. Adams, E.C. Burdette & Chris J. Diederich. (2018) Transurethral high-intensity ultrasound for treatment of stress urinary incontinence (SUI): simulation studies with patient-specific models. International Journal of Hyperthermia 34:8, pages 1236-1247.
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Jakub Mesicek & Kamil Kuca. (2018) Summary of numerical analyses for therapeutic uses of laser-activated gold nanoparticles. International Journal of Hyperthermia 34:8, pages 1255-1264.
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Na Yin, Liang Hu, Zhi-Bo Xiao, Chang Liu, Wen-Zhi Chen, Neil Roberts, Jin-Yun Chen & Zhi-Biao Wang. (2018) Factors influencing thermal injury to skin and abdominal wall structures in HIFU ablation of uterine fibroids. International Journal of Hyperthermia 34:8, pages 1298-1303.
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Fatemeh Adibzadeh, Margarethus M. Paulides & Gerard C. van Rhoon. (2018) SAR thresholds for electromagnetic exposure using functional thermal dose limits. International Journal of Hyperthermia 34:8, pages 1248-1254.
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Akke Bakker, Rebecca Holman, Dario B. Rodrigues, Hana Dobšíček Trefná, Paul R. Stauffer, Geertjan van Tienhoven, Coen R. N. Rasch & Hans Crezee. (2018) Analysis of clinical data to determine the minimum number of sensors required for adequate skin temperature monitoring of superficial hyperthermia treatments. International Journal of Hyperthermia 34:7, pages 910-917.
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Deniz Gazel & Mehmet Yılmaz. (2018) Are infectious diseases and microbiology new fields for thermal therapy research?. International Journal of Hyperthermia 34:7, pages 918-924.
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Drew Mitchell, Samuel Fahrenholtz, Christopher MacLellan, Dhiego Bastos, Ganesh Rao, Sujit Prabhu, Jeffrey Weinberg, John Hazle, Jason Stafford & David Fuentes. (2018) A heterogeneous tissue model for treatment planning for magnetic resonance-guided laser interstitial thermal therapy. International Journal of Hyperthermia 34:7, pages 943-952.
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Kyosuke Tomura, Takayuki Ohguri, Hendrik Thijmen Mulder, Motohiro Murakami, Sota Nakahara, Katsuya Yahara & Yukunori Korogi. (2018) The usefulness of mobile insulator sheets for the optimisation of deep heating area for regional hyperthermia using a capacitively coupled heating method: phantom, simulation and clinical prospective studies. International Journal of Hyperthermia 34:7, pages 1092-1103.
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Christopher J. MacLellan, David Fuentes, Sujit Prabhu, Ganesh Rao, Jeffrey S. Weinberg, John D. Hazle & R. Jason Stafford. (2018) A methodology for thermal dose model parameter development using perioperative MRI. International Journal of Hyperthermia 34:6, pages 687-696.
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Pierre-Olivier Champagne, Harrison Westwick, Alain Bouthillier & Mohamad Sawan. (2018) Colloidal Stability of Superparamagnetic Iron Oxide Nanoparticles in the Central Nervous System: A Review. Nanomedicine 13:11, pages 1385-1400.
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Takayuki Ohguri, Yoko Harima, Hajime Imada, Hideyuki Sakurai, Tatsuya Ohno, Yoshiyuki Hiraki, Koh Tuji, Masahiro Tanaka & Hiromi Terashima. (2018) Relationships between thermal dose parameters and the efficacy of definitive chemoradiotherapy plus regional hyperthermia in the treatment of locally advanced cervical cancer: data from a multicentre randomised clinical trial. International Journal of Hyperthermia 34:4, pages 461-468.
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Erica B. Ricker, Haydar A. S. Aljaafari, Trigg M. Bader, Bryce S. Hundley & Eric Nuxoll. (2018) Thermal shock susceptibility and regrowth of Pseudomonas aeruginosa biofilms. International Journal of Hyperthermia 34:2, pages 168-176.
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Gerard C. van Rhoon. (2016) Is CEM43 still a relevant thermal dose parameter for hyperthermia treatment monitoring?. International Journal of Hyperthermia 32:1, pages 50-62.
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William C. Dewey$suffix/text()$suffix/text() & Chris J. Diederich. (2009) Hyperthermia classic commentary: ‘Arrhenius relationships from the molecule and cell to the clinic’ by William Dewey, , 10:457–483, 1994. International Journal of Hyperthermia 25:1, pages 21-24.
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Pol-Edern Le Renard, Franz Buchegger, Alke Petri-Fink, Frederik Bosman, Daniel Rüfenacht, Heinrich Hofmann, Eric Doelker & Olivier Jordan. (2009) Local moderate magnetically induced hyperthermia using an implant formed in situ in a mouse tumor model. International Journal of Hyperthermia 25:3, pages 229-239.
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Mathieu Burtnyk, Rajiv Chopra & Michael J. Bronskill. (2009) Quantitative analysis of 3-D conformal MRI-guided transurethral ultrasound therapy of the prostate: Theoretical simulations. International Journal of Hyperthermia 25:2, pages 116-131.
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P. M. A. van Haaren, M. C. C. M. Hulshof, H. P. Kok, S. Oldenborg, E. D. Geijsen, J. J. B. Van Lanschot & J. Crezee. (2008) Relation between body size and temperatures during locoregional hyperthermia of oesophageal cancer patients. International Journal of Hyperthermia 24:8, pages 663-674.
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J. Andrew Mackay & Ashutosh Chilkoti. (2008) Temperature sensitive peptides: Engineering hyperthermia-directed therapeutics. International Journal of Hyperthermia 24:6, pages 483-495.
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Stephanie Solazzo, Pawel Mertyna, Himija Peddi, Muneeb Ahmed, Clare Horkan & S. Nahum Goldberg$suffix/text()$suffix/text(). (2008) RF ablation with adjuvant therapy: Comparison of external beam radiation and liposomal doxorubicin on ablation efficacy in an animal tumor model. International Journal of Hyperthermia 24:7, pages 560-567.
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Pawel Mertyna, Mark W. Dewhirst, Elkan Halpern, Wallace Goldberg & S. Nahum Goldberg. (2008) Radiofrequency ablation: The effect of distance and baseline temperature on thermal dose required for coagulation. International Journal of Hyperthermia 24:7, pages 550-559.
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José A. Peñagarícano, Eduardo Moros, Petr Novák, Yulong Yan & Peter Corry. (2008) Feasibility of concurrent treatment with the scanning ultrasound reflector linear array system (SURLAS) and the helical tomotherapy system. International Journal of Hyperthermia 24:5, pages 377-388.
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Ann P O’Rourke, Dieter Haemmerich, Punit Prakash, Mark C Converse, David M Mahvi & John G Webster. (2007) Current status of liver tumor ablation devices. Expert Review of Medical Devices 4:4, pages 523-537.
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Jeffery H. Wootton, Anthony B. Ross & Chris J. Diederich. (2007) Prostate thermal therapy with high intensity transurethral ultrasound: The impact of pelvic bone heating on treatment delivery. International Journal of Hyperthermia 23:8, pages 609-622.
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I. Rivens, A. Shaw, J. Civale & H. Morris. (2007) Treatment monitoring and thermometry for therapeutic focused ultrasound. International Journal of Hyperthermia 23:2, pages 121-139.
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>Gail ter Haar & Constantin Coussios. (2007) High intensity focused ultrasound: Physical principles and devices. International Journal of Hyperthermia 23:2, pages 89-104.
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Hao-Li Liu, Win-Li Lin & Yung-Yaw Chen. (2007) A fast and conformal heating scheme for producing large thermal lesions using a 2D ultrasound phased array. International Journal of Hyperthermia 23:1, pages 69-82.
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Ekaterina Vorotnikova, Robert Ivkov, Allan Foreman, Mark Tries & Susan J. Braunhut. (2006) The magnitude and time-dependence of the apoptotic response of normal and malignant cells subjected to ionizing radiation versus hyperthermia. International Journal of Radiation Biology 82:8, pages 549-559.
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>Peter Wust, Uwe Gneveckow, >Peter Wust, Uwe Gneveckow, Manfred Johannsen, Dirk Böhmer, Thomas Henkel, Frank Kahmann, Jalid Sehouli, Roland Felix, Jens Ricke & Andreas Jordan. (2006) Magnetic nanoparticles for interstitial thermotherapy – feasibility, tolerance and achieved temperatures. International Journal of Hyperthermia 22:8, pages 673-685.
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Bert Hildebrandt, Dagmar Schoeler, Bert Hildebrandt, Dagmar Schoeler, Frauke Ringel, Thoralf Kerner, Peter Wust, Hanno Riess & Folke Schriever. (2006) Differential gene expression in peripheral blood lymphocytes of cancer patients treated with whole body hyperthermia and chemotherapy: A pilot study. International Journal of Hyperthermia 22:8, pages 625-635.
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Ellen Jones, Donald Thrall, Mark W. Dewhirst & Zeljko Vujaskovic. (2006) Prospective thermal dosimetry: The key to hyperthermia's future. International Journal of Hyperthermia 22:3, pages 247-253.
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Chris J. Diederich. (2005) Thermal ablation and high-temperature thermal therapy: Overview of technology and clinical implementation. International Journal of Hyperthermia 21:8, pages 745-753.
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Mark W. Dewhirst, Zeljko Vujaskovic, Ellen Jones & Donald Thrall. (2005) Re-setting the biologic rationale for thermal therapy. International Journal of Hyperthermia 21:8, pages 779-790.
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G. Perugia, M. Liberti, P. Vicini, F. Colistro & V. Gentile. (2005) Role of hyperthermia in the treatment of Peyronie's disease: A preliminary study. International Journal of Hyperthermia 21:4, pages 367-374.
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G. Perugia, M. Liberti, P. Vicini, F. Colistro & V. Gentile. (2005) Use of local hyperthermia as prophylaxis of fibrosis and modification in penile length following radical retropubic prostatectomy. International Journal of Hyperthermia 21:4, pages 359-365.
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K.-S. Cheng & R. B. Roemer. (2005) Closed-form solution for the thermal dose delivered during single pulse thermal therapies. International Journal of Hyperthermia 21:3, pages 215-230.
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M. L. Hauck & M. R. Zalutsky. (2005) Enhanced tumour uptake of radiolabelled antibodies by hyperthermia. Part II: Application of the thermal equivalency equation. International Journal of Hyperthermia 21:1, pages 13-27.
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L. Kheifets, M. Repacholi & R. Saunders. (2003) Thermal stress and radiation protection principles. International Journal of Hyperthermia 19:3, pages 215-224.
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M. J. Edwards, R. D. Saunders & K. Shiota. (2003) Effects of heat on embryos and foetuses. International Journal of Hyperthermia 19:3, pages 295-324.
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