Acta Oncologica, Volume 62, Issue 11 (2023)

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Acta Oncologica, Volume 62, Issue 11 (2023)

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21st Acta Oncologica Symposium—BiGART 2023 - Biology-Guided Adaptive Radiotherapy - Aarhus, Denmark. June 20-21, 2023

Editorial

Editorial
Think big–think BiGART. The 21st Acta Oncologica Symposium—BiGART 2023
Jesper Grau Eriksen, Birgitte Vrou Offersen, Morten Høyer, Cai Grau & Jens Overgaard
Pages: 1357-1359
Published online: 07 Nov 2023
First Page PreviewforThink big–think BiGART. The 21st Acta Oncologica Symposium—BiGART 2023 | Full Text | References | PDF (825.7 KB) | EPUB
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Original Article: BiGART 2023 Issue

Article
A systematic review on clinical adaptive radiotherapy for head and neck cancer
Anne Marie Lindegaard, Katrin Håkansson, Mogens Bernsdorf, Anita B. Gothelf, Claus A. Kristensen, Lena Specht, Ivan R. Vogelius & Jeppe Friborg
Pages: 1360-1368
Published online: 10 Aug 2023
AbstractforA systematic review on clinical adaptive radiotherapy for head and neck cancer | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Letter to the Editor: BiGART 2023 Issue

CBCT-based online adaptive radiotherapy for head and neck cancer – dosimetric evaluation of first clinical experience
K. Håkansson, E. Giannoulis, A. Lindegaard, J. Friborg & I. Vogelius
Pages: 1369-1374
Published online: 15 Sep 2023
First Page PreviewforCBCT-based online adaptive radiotherapy for head and neck cancer – dosimetric evaluation of first clinical experience | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Original Articles: BiGART 2023 Issue

Article
Importance of tumor volume, overall treatment time and fractionation sensitivity for p16-positive and p16-negative oropharyngeal tumors
Gabriel Adrian, Maria Gebre-Medhin & Per Nilsson
Pages: 1375-1383
Published online: 08 Sep 2023
AbstractforImportance of tumor volume, overall treatment time and fractionation sensitivity for p16-positive and p16-negative oropharyngeal tumors | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
HPV testing versus p16 immunohistochemistry in oropharyngeal squamous cell carcinoma: results from the DAHANCA 19 study
Jacob Kinggaard Lilja-Fischer, Morten Horsholt Kristensen, Pernille Lassen, Torben Steiniche, Trine Tramm, Magnus Stougaard, Christian Maare, Jørgen Johansen, Hanne Primdahl, Claus Andrup Kristensen, Maria Andersen, Jesper Grau Eriksen & Jens Overgaard
Pages: 1384-1388
Published online: 07 Nov 2023
AbstractforHPV testing versus p16 immunohistochemistry in oropharyngeal squamous cell carcinoma: results from the DAHANCA 19 study | Full Text | References | PDF (715.4 KB) | EPUB
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Letter to the Editor: BiGART 2023 Issue

Biologically guided automated treatment planning and evaluation: potential for treatment adaptation in head and neck cancer
Ana Ureba, Iuliana Toma-Dasu & Marta Lazzeroni
Pages: 1389-1393
Published online: 29 Aug 2023
First Page PreviewforBiologically guided automated treatment planning and evaluation: potential for treatment adaptation in head and neck cancer | Full Text | References | PDF (955.8 KB) | EPUB | Supplemental
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Original Articles: BiGART 2023 Issue

Article
Socioeconomic position and the pre-diagnostic interval among patients diagnosed with head and neck squamous cell carcinoma - a population-based study from DAHANCA
Maja Halgren Olsen, Thomas Maltesen, Pernille Lassen, Trille Kristina Kjaer, Jørgen Johansen, Hanne Primdahl, Elo Andersen, Claus Andrup Kristensen, Maria Andersen, Mohammad Farhadi, Jens Overgaard & Susanne Oksbjerg Dalton
Pages: 1394-1402
Published online: 06 Sep 2023
AbstractforSocioeconomic position and the pre-diagnostic interval among patients diagnosed with head and neck squamous cell carcinoma - a population-based study from DAHANCA | Full Text | References | PDF (864.1 KB) | EPUB | Supplemental
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Article
Accelerated loss of lean body mass in head and neck cancer patients during cisplatin-based chemoradiation
Simon Lønbro, Søren Gam, Anne Pernille Hermann, Christian Rønn Hansen & Jørgen Johansen
Pages: 1403-1411
Published online: 17 Aug 2023
AbstractforAccelerated loss of lean body mass in head and neck cancer patients during cisplatin-based chemoradiation | Full Text | References | PDF (1.3 MB) | EPUB
  • 165 Views
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Article
Dose planning study of proton versus photon radiotherapy for head and neck squamous cell carcinoma of unknown primary in the primary and recurrent setting
Anne Ivalu Sander Holm, Ulrik Vindelev Elstrøm, Signe Bergliot Nielsen & Kenneth Jensen
Pages: 1412-1417
Published online: 07 Nov 2023
AbstractforDose planning study of proton versus photon radiotherapy for head and neck squamous cell carcinoma of unknown primary in the primary and recurrent setting | Full Text | References | PDF (769 KB) | EPUB | Supplemental
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Article
Consistency in contouring of organs at risk by artificial intelligence vs oncologists in head and neck cancer patients
Camilla Panduro Nielsen, Ebbe Laugaard Lorenzen, Kenneth Jensen, Nis Sarup, Carsten Brink, Bob Smulders, Anne Ivalu Sander Holm, Eva Samsøe, Martin Skovmos Nielsen, Patrik Sibolt, Peter Sandegaard Skyt, Ulrik Vindelev Elstrøm, Jørgen Johansen, Ruta Zukauskaite, Jesper Grau Eriksen, Mohammad Farhadi, Maria Andersen, Christian Maare, Jens Overgaard, Cai Grau, Jeppe Friborg & Christian Rønn Hansen
Pages: 1418-1425
Published online: 13 Sep 2023
AbstractforConsistency in contouring of organs at risk by artificial intelligence vs oncologists in head and neck cancer patients | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Different benefits of adaptive radiotherapy for different histologies of NSCLC
Marie Tvilum, Christina Maria Lutz, Marianne Marquard Knap, Lone Hoffmann, Azza Ahmed Khalil, Marianne Ingerslev Holt, Maria Kandi, Hjørdis Hjalting Schmidt, Ane L. Appelt, Markus Alber & Ditte S. Møller
Pages: 1426-1432
Published online: 07 Nov 2023
AbstractforDifferent benefits of adaptive radiotherapy for different histologies of NSCLC | Full Text | References | PDF (1,016.1 KB) | EPUB
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Article
Outcome of conventional radiotherapy in small centrally located tumours or lymph nodes: minimal toxicity, remarkable survival but challenging loco-regional control
M. M. Knap, S. Khan, A. A. Khalil, D. S. Møller & L. Hoffmann
Pages: 1433-1439
Published online: 14 Sep 2023
AbstractforOutcome of conventional radiotherapy in small centrally located tumours or lymph nodes: minimal toxicity, remarkable survival but challenging loco-regional control | Full Text | References | PDF (894.7 KB) | EPUB | Supplemental
  • 84 Views
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Article
Patient-reported persistent symptoms after radiotherapy and association with quality of life for prostate cancer survivors
Sofia Spampinato, Tiziana Rancati, Justyna Magdalena Waskiewicz, Barbara Avuzzi, Elisabetta Garibaldi, Adriana Faiella, Elisa Villa, Alessandro Magli, Domenico Cante, Giuseppe Girelli, Marco Gatti, Barbara Noris Chiorda, Luciana Rago, Paolo Ferrari, Cristina Piva, Maddalena Pavarini, Riccardo Valdagni, Vittorio Vavassori, Fernando Munoz, Giuseppe Sanguineti, Nadia Di Muzio, Kathrin Kirchheiner, Claudio Fiorino & Cesare Cozzarini
Pages: 1440-1450
Published online: 07 Nov 2023
AbstractforPatient-reported persistent symptoms after radiotherapy and association with quality of life for prostate cancer survivors | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Letter to the Editor: BiGART 2023 Issue

A systematic planning method to spare the rectal wall in radiotherapy of prostate cancer
Kirsten Jakobsen, Laura Patricia Kaplan, Romain Marsguerra, Marko Bebek, Kenneth Francis Hoffland & Eva Samsoee Hinsby
Pages: 1451-1454
Published online: 15 Sep 2023
First Page PreviewforA systematic planning method to spare the rectal wall in radiotherapy of prostate cancer | Full Text | References | PDF (648.9 KB) | EPUB
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Original Articles: BiGART 2023 Issue

Article
Plan robustness evaluation strategies in whole-pelvic proton therapy for high-risk prostate cancer patients within a randomised clinical trial
Sofie Tilbæk, Stine Elleberg Petersen, Liliana Stolarczyk, Anne Vestergaard, Heidi S. Rønde, Lise N. Bentzen, Jimmi Søndergaard, Morten Høyer & Ludvig Paul Muren
Pages: 1455-1460
Published online: 07 Nov 2023
AbstractforPlan robustness evaluation strategies in whole-pelvic proton therapy for high-risk prostate cancer patients within a randomised clinical trial | Full Text | References | PDF (876.5 KB) | EPUB | Supplemental
  • 176 Views
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Article
Proton range uncertainty caused by synthetic computed tomography generated with deep learning from pelvic magnetic resonance imaging
Liheng Tian & Armin Lühr
Pages: 1461-1469
Published online: 13 Sep 2023
AbstractforProton range uncertainty caused by synthetic computed tomography generated with deep learning from pelvic magnetic resonance imaging | Full Text | References | PDF (1.3 MB) | EPUB
  • 135 Views
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Article
Clinical outcomes using a 3D printed tandem-needle-template and the EMBRACE-II planning aims for image guided adaptive brachytherapy in locally advanced cervical cancer
Anne Cobussen, Primoz Petric, Christian Nielsen Wulff, Simon Buus, Harald Spejlborg, Søren Kynde Nielsen, Anders Traberg, Bjarne Meisner, Steffen Hokland & Jacob Christian Lindegaard
Pages: 1470-1478
Published online: 18 Aug 2023
AbstractforClinical outcomes using a 3D printed tandem-needle-template and the EMBRACE-II planning aims for image guided adaptive brachytherapy in locally advanced cervical cancer | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Co-occurrence of symptoms after radiochemotherapy in locally advanced cervix cancer patients: a cluster analysis
Marta Pelizzola, Kari Tanderup, Supriya Chopra, Ina M. Jürgenliemk-Schulz, Remi Nout, Kathrin Kirchheiner & Sofia Spampinato
Pages: 1479-1487
Published online: 07 Nov 2023
AbstractforCo-occurrence of symptoms after radiochemotherapy in locally advanced cervix cancer patients: a cluster analysis | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 175 Views
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Article
Clinical implications of dose to functional lung volumes in the trimodality treatment of esophageal cancer
Pieter Populaire, Gilles Defraene, Philippe Nafteux, Lieven Depypere, Johnny Moons, Sofie Isebaert & Karin Haustermans
Pages: 1488-1495
Published online: 29 Aug 2023
AbstractforClinical implications of dose to functional lung volumes in the trimodality treatment of esophageal cancer | Full Text | References | PDF (821.3 KB) | EPUB | Supplemental
  • 116 Views
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Article
Interim analysis of patient-reported outcome compliance and dosimetry in a phase 3 randomized clinical trial of oesophagus-sparing spinal radiotherapy
Anna Mann Nielsen, Katrine Smedegaard Storm, Michael R. T. Laursen, Vanja Remberg Gram, Laura Ann Rechner, Wiviann Ottosson, Morten Hiul Suppli, Patrik Sibolt, Claus F. Behrens, Ivan R. Vogelius & Gitte F. Persson
Pages: 1496-1501
Published online: 30 Aug 2023
AbstractforInterim analysis of patient-reported outcome compliance and dosimetry in a phase 3 randomized clinical trial of oesophagus-sparing spinal radiotherapy | Full Text | References | PDF (641.7 KB) | EPUB | Supplemental
  • 124 Views
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Article
Treating brain metastases in metastatic breast cancer: outcomes after stereotactic radiosurgery examined in a retrospective, single-center cohort analysis
Julie F. Depner, Tobias Berg, Bent Ejlertsen, Lærke W. Andreasen, Søren Møller & Maja V. Maraldo
Pages: 1502-1510
Published online: 07 Nov 2023
AbstractforTreating brain metastases in metastatic breast cancer: outcomes after stereotactic radiosurgery examined in a retrospective, single-center cohort analysis | Full Text | References | PDF (1.2 MB) | EPUB
  • 117 Views
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Article
The impact of short-course hypofractionated radiotherapy on multimodality treatment utilisation, compliance, and outcome in glioblastoma patients: a Danish patterns of care study
Vishnuga Sivarasah Vamsi, Slavka Lukacova, Rikke Hedegaard Dahlrot, Trine Lignell Guldberg, Anders Rosendal Korshøj, Aida Muhic & Anouk Kirsten Trip
Pages: 1511-1519
Published online: 09 Aug 2023
AbstractforThe impact of short-course hypofractionated radiotherapy on multimodality treatment utilisation, compliance, and outcome in glioblastoma patients: a Danish patterns of care study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 147 Views
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Letters to the Editor: BiGART 2023 Issue

Radiation dose to sleep-relevant brain structures linked to impaired sleep quality in primary brain tumor patients
Ali Amidi, Lene Haldbo-Classen, Jesper F. Kallehauge, Lisa M. Wu, Robert Zachariae, Yasmin Lassen-Ramshad, Slavka Lukacova & Morten Høyer
Pages: 1520-1525
Published online: 09 Sep 2023
First Page PreviewforRadiation dose to sleep-relevant brain structures linked to impaired sleep quality in primary brain tumor patients | Full Text | References | PDF (989.8 KB) | EPUB
  • 551 Views
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Dose-accumulation analysis of target and organs at risk with clinical outcome after re-irradiation of diffuse midline glioma
Daniella Elisabet Østergaard, Isak Wahlstedt, Morten Jørgensen, Mimi Kjærsgaard, Rene Mathiasen, Karsten Nysom, Astrid Sehested, Ivan Richter Vogelius & Maja Vestmø Maraldo
Pages: 1526-1530
Published online: 07 Nov 2023
First Page PreviewforDose-accumulation analysis of target and organs at risk with clinical outcome after re-irradiation of diffuse midline glioma | Full Text | References | PDF (895.7 KB) | EPUB | Supplemental
  • 523 Views
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Dose exposure to an adult present in the treatment room during pediatric pencil beam scanning proton therapy
Johannes Tjelta, Kristian Ytre-Hauge, Erlend Lyngholm, Andreas Handeland, Helge Henjum & Camilla Stokkevåg
Pages: 1531-1535
Published online: 07 Sep 2023
First Page PreviewforDose exposure to an adult present in the treatment room during pediatric pencil beam scanning proton therapy | Full Text | References | PDF (1.1 MB) | EPUB
  • 588 Views
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Linear energy transfer-inclusive brainstem necrosis risk models applied to an independent paediatric proton therapy cohort
Andreas H. Handeland, Peter MT. Lægdsmand, Laura Toussaint, Camilla H. Stokkevåg, Yasmin A. Lassen-Ramshad, Rasmus Klitgaard, Helge Henjum, Kristian S. Ytre-Hauge, Daniel J. Indelicato, Johannes Tjelta, Erlend Lyngholm & Ludvig P. Muren
Pages: 1536-1540
Published online: 07 Sep 2023
First Page PreviewforLinear energy transfer-inclusive brainstem necrosis risk models applied to an independent paediatric proton therapy cohort | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 424 Views
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Prediction of dose-sparing by protons assessed by a knowledge-based planning tool in radiotherapy of brain tumours
Bob Smulders, Liliana Stolarczyk, Klaus Seiersen, Ole Nørrevang, Bente Sommer Kristensen, Deborah Anne Schut, Karsten Thomsen, Yasmin Lassen-Ramshad, Morten Høyer, Aida Muhic & Anne Vestergaard
Pages: 1541-1545
Published online: 07 Nov 2023
First Page PreviewforPrediction of dose-sparing by protons assessed by a knowledge-based planning tool in radiotherapy of brain tumours | Full Text | References | PDF (705 KB) | EPUB
  • 308 Views
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Classification of laterality and mastectomy/lumpectomy for breast cancer patients for improved performance of deep learning auto segmentation
Helena Vivancos Bargalló, Line Bjerregaard Stick, Stine Sofia Korreman, Camilla Kronborg, Mathias M. Nielsen, Asbjørn Christian Borgen, Birgitte Vrou Offersen, Ole Nørrevang & Jesper F. Kallehauge
Pages: 1546-1550
Published online: 16 Aug 2023
First Page PreviewforClassification of laterality and mastectomy/lumpectomy for breast cancer patients for improved performance of deep learning auto segmentation | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Original Article: BiGART 2023 Issue

Article
Geometric distortions in clinical MRI sequences for radiotherapy: insights gained from a multicenter investigation
Signe Winther Hasler, Jesper Folsted Kallehauge, Rasmus Hvass Hansen, Eva Samsøe, Dennis Tideman Arp, Henrik Dahl Nissen, Jens M. Edmund, Uffe Bernchou & Faisal Mahmood
Pages: 1551-1560
Published online: 07 Nov 2023
AbstractforGeometric distortions in clinical MRI sequences for radiotherapy: insights gained from a multicenter investigation | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 283 Views
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Letter to the Editor: BiGART 2023 Issue

Parameters for proton minibeam radiotherapy using a clinical scanning beam system
Fardous Reaz, Mateusz Krzysztof Sitarz, Erik Traneus & Niels Bassler
Pages: 1561-1565
Published online: 07 Nov 2023
First Page PreviewforParameters for proton minibeam radiotherapy using a clinical scanning beam system | Full Text | References | PDF (805.2 KB) | EPUB
  • 621 Views
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Original Articles: BiGART 2023 Issue

Article
An experimental setup for proton irradiation of a murine leg model for radiobiological studies
Cathrine Bang Overgaard, Fardous Reaz, Mateusz Sitarz, Per Poulsen, Jens Overgaard, Niels Bassler, Cai Grau & Brita Singers Sørensen
Pages: 1566-1573
Published online: 21 Aug 2023
AbstractforAn experimental setup for proton irradiation of a murine leg model for radiobiological studies | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 857 Views
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Article
Acute normal tissue responses in a murine model following fractionated irradiation of the head and neck with protons or X-rays
Olga Zlygosteva, Inga Solgård Juvkam, Delmon Arous, Mateusz Sitarz, Brita Singers Sørensen, Christina Ankjærgaard, Claus E. Andersen, Hilde Kanli Galtung, Tine Merete Søland, Nina Jeppesen Edin & Eirik Malinen
Pages: 1574-1580
Published online: 13 Sep 2023
AbstractforAcute normal tissue responses in a murine model following fractionated irradiation of the head and neck with protons or X-rays | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 1003 Views
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Article
Using immunotherapy to enhance the response of a C3H mammary carcinoma to proton radiation
Steffen Nielsen, Mateusz K. Sitarz, Priyanshu M. Sinha, Charlemagne A. Folefac, Morten Høyer, Brita S. Sørensen & Michael R. Horsman
Pages: 1581-1586
Published online: 27 Jul 2023
AbstractforUsing immunotherapy to enhance the response of a C3H mammary carcinoma to proton radiation | Full Text | References | PDF (726.9 KB) | EPUB
  • 543 Views
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Correction

Correction
Correction
Page: 1587
Published online: 07 Nov 2023
CitationforCorrection | Full Text | PDF (138.7 KB) | EPUB
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