Nucleosides, Nucleotides & Nucleic Acids, Volume 20, Issue 4-7 (2001)

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Nucleosides, Nucleotides & Nucleic Acids, Volume 20, Issue 4-7 (2001)

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Original Articles

Article
ACYCLIC/CARBOCYCLIC GUANOSINE ANALOGUES AS ANTI-HERPESVIRUS AGENTS
E. De Clercq, G. Andrei, R. Snoeck, L. De Bolle, L. Naesens, B. Degrève, J. Balzarini, Y. Zhang, D. Schols, P. Leyssen, C. Ying & J. Neyts
Pages: 271-285
Published online: 07 Feb 2007
AbstractforACYCLIC/CARBOCYCLIC GUANOSINE ANALOGUES AS ANTI-HERPESVIRUS AGENTS | Full Text | References | PDF (136.5 KB)
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Article
NOVEL ARYL SUBSTITUTED BICYCLIC FURO NUCLEOSIDES AS EXTREMELY POTENT AND SELECTIVE ANTI-VZV AGENTS
Christopher McGuigan, Hubert Barucki, Antonella Carangio, Sally Blewett, Sheila Srinivasan, Graciela Andrei, Robert Snoeck, Erik De Clercq & Jan Balzarini
Pages: 287-296
Published online: 07 Feb 2007
First Page PreviewforNOVEL ARYL SUBSTITUTED BICYCLIC FURO NUCLEOSIDES AS EXTREMELY POTENT AND SELECTIVE ANTI-VZV AGENTS | Full Text | References | PDF (117 KB)
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Article
ACTIVATION OF ANTI-REVERSE TRANSCRIPTASE NUCLEOTIDE ANALOGS BY NUCLEOSIDE DIPHOSPHATE KINASE: IMPROVEMENT BY α-BORANOPHOSPHATE SUBSTITUTION
Benoit Schneider, Philippe Meyer, Simon Sarfati, Laurence Mulard, Catherine Guerreiro, Joëlle Boretto, Joël Janin, Michel Véron, Dominique Deville-Bonne & Bruno Canard
Pages: 297-306
Published online: 07 Feb 2007
AbstractforACTIVATION OF ANTI-REVERSE TRANSCRIPTASE NUCLEOTIDE ANALOGS BY NUCLEOSIDE DIPHOSPHATE KINASE: IMPROVEMENT BY α-BORANOPHOSPHATE SUBSTITUTION | Full Text | References | PDF (197.5 KB)
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Article
SYNTHESIS, HYDROLYSIS AND ANTI-EBV ACTIVITY OF A SERIES OF 3′-MODIFIED cycloSal-BVDUMP PRONUCLEOTIDES
C. Meier, A. Lomp, A. Meerbach & P. Wutzler
Pages: 307-314
Published online: 07 Feb 2007
AbstractforSYNTHESIS, HYDROLYSIS AND ANTI-EBV ACTIVITY OF A SERIES OF 3′-MODIFIED cycloSal-BVDUMP PRONUCLEOTIDES | Full Text | References | PDF (120.5 KB)
  • 61 Views
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Article
DESIGN OF NEW MONONUCLEOTIDE PRODRUGS: ARYL (SATE) PHOSPHOTRIESTER DERIVATIVES
S. Peyrottes, N. Schlienger, T. Beltran, I. Lefebvre, A. Pompon, G. Gosselin, A.-M. Aubertin, J.-L. Imbach & C. Périgaud
Pages: 315-321
Published online: 07 Feb 2007
AbstractforDESIGN OF NEW MONONUCLEOTIDE PRODRUGS: ARYL (SATE) PHOSPHOTRIESTER DERIVATIVES | Full Text | References | PDF (107.6 KB)
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Article
SYNTHESIS AND ANTICANCER ACTIVITY OF 4-AMINO-5-OXO-8-(β-D-XYLOFURANOSYL) PYRIDO[2,3-d]PYRIMIDINE
Zbigniew Pietrzkowski, Jean-Luc Girardet, Cathey Esler & Guangyi Wang
Pages: 323-328
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTICANCER ACTIVITY OF 4-AMINO-5-OXO-8-(β-D-XYLOFURANOSYL) PYRIDO[2,3-d]PYRIMIDINE | Full Text | References | PDF (143.7 KB)
  • 49 Views
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Article
SYNTHESIS AND ANTIVIRAL ACTIVITY OF METHYLENEDIFLUOROCYCLOPROPANE ANALOGUES OF NUCLEOSIDES
R. Wang, M. B. Ksebati, J. C. Drach & J. Zemlicka
Pages: 329-332
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTIVIRAL ACTIVITY OF METHYLENEDIFLUOROCYCLOPROPANE ANALOGUES OF NUCLEOSIDES | Full Text | References | PDF (85.3 KB)
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Article
RIBOSE MODIFIED NUCLEOSIDES AND NUCLEOTIDES AS LIGANDS FOR PURINE RECEPTORS
K. A. Jacobson, R. G. Ravi, E. Nandanan, H. S. Kim, S. Moro, Y. C. Kim, K. Lee, D. Barak, V. E. Marquez & X. D. Ji
Pages: 333-341
Published online: 07 Feb 2007
AbstractforRIBOSE MODIFIED NUCLEOSIDES AND NUCLEOTIDES AS LIGANDS FOR PURINE RECEPTORS | Full Text | References | PDF (132.6 KB)
  • 71 Views
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Article
2-SUBSTITUTED PI SYSTEM DERIVATIVES OF ADENOSINE THAT ARE CORONARY VASODILATORS ACTING VIA THE A2A ADENOSINE RECEPTOR
J. Zablocki, V. Palle, B. Blackburn, E. Elzein, G. Nudelman, S. Gothe, Z. Gao, Z. Li, S. Meyer & L. Belardinelli
Pages: 343-360
Published online: 07 Feb 2007
Abstractfor2-SUBSTITUTED PI SYSTEM DERIVATIVES OF ADENOSINE THAT ARE CORONARY VASODILATORS ACTING VIA THE A2A ADENOSINE RECEPTOR | Full Text | References | PDF (335.4 KB)
  • 144 Views
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Article
FLUORESCENCE RESONANCE ENERGY TRANSFER DYE NUCLEOTIDE TERMINATORS: A NEW SYNTHETIC APPROACH FOR HIGH-THROUGHOUT DNA SEQUENCING
Satyam Nampalli, Mahesh Khot, John R. Nelson, Parke K. Flick, Carl W. Fuller & Shiv Kumar
Pages: 361-367
Published online: 07 Feb 2007
AbstractforFLUORESCENCE RESONANCE ENERGY TRANSFER DYE NUCLEOTIDE TERMINATORS: A NEW SYNTHETIC APPROACH FOR HIGH-THROUGHOUT DNA SEQUENCING | Full Text | References | PDF (627.6 KB)
  • 103 Views
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Article
DESIGN OF MULTIDYE SYSTEMS FOR FRET-BASED APPLICATIONS
Mikhail S. Shchepinov & Vladimir A. Korshun
Pages: 369-374
Published online: 07 Feb 2007
AbstractforDESIGN OF MULTIDYE SYSTEMS FOR FRET-BASED APPLICATIONS | Full Text | References | PDF (176.1 KB)
  • 120 Views
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Article
ANALYSIS OF ANTI-HIV NUCLEOSIDE INHIBITORS BY CAPILLARY ELECTROPHORESIS-ELECTROSPRAY IONIZATION MASS SPECTROMETRY
L. A. Agrofoglio, X. Cahours, T. T. Tran, H. Dessans, C. Kieda & P. Morin
Pages: 375-381
Published online: 07 Feb 2007
AbstractforANALYSIS OF ANTI-HIV NUCLEOSIDE INHIBITORS BY CAPILLARY ELECTROPHORESIS-ELECTROSPRAY IONIZATION MASS SPECTROMETRY | Full Text | References | PDF (108.4 KB)
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Article
THE CONFORMATIONAL SPACE OF NASCENT PEPTIDE-ACCEPTING 3′-AMINOACYL RIBONUCLEOS(T)IDES: 1H NMR DATA AND AB INITIO CALCULATIONS OF PUROMYCIN AND SOME SYNTHETIC ANALOGS
Nhat Quang Nguyen Trung, Peter Strazewski, Martin Olsson & Måns Ehrenberg
Pages: 383-384
Published online: 07 Feb 2007
First Page PreviewforTHE CONFORMATIONAL SPACE OF NASCENT PEPTIDE-ACCEPTING 3′-AMINOACYL RIBONUCLEOS(T)IDES: 1H NMR DATA AND AB INITIO CALCULATIONS OF PUROMYCIN AND SOME SYNTHETIC ANALOGS | Full Text | References | PDF (72.1 KB)
  • 19 Views
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Article
UNDERSTANDING THE MODE OF ACTION OF L-NUCLEOSIDES AS ANTIVIRAL AGENTS: A MOLECULAR MODELING APPROACH
Kyeong Lee, Youhoon Chong & Chung K. Chu
Pages: 385-388
Published online: 07 Feb 2007
AbstractforUNDERSTANDING THE MODE OF ACTION OF L-NUCLEOSIDES AS ANTIVIRAL AGENTS: A MOLECULAR MODELING APPROACH | Full Text | References | PDF (118.3 KB)
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Article
LNA (LOCKED NUCLEIC ACID) AND THE DIASTEREOISOMERIC α-L-LNA: CONFORMATIONAL TUNING AND HIGH-AFFINITY RECOGNITION OF DNA/RNA TARGETS
Jesper Wengel, Michael Petersen, Kathrine E. Nielsen, Gitte A. Jensen, Anders E. Håkansson, Ravindra Kumar, Mads D. Sørensen, Vivek K. Rajwanshi, Torsten Bryld & Jens Peter Jacobsen
Pages: 389-396
Published online: 07 Feb 2007
AbstractforLNA (LOCKED NUCLEIC ACID) AND THE DIASTEREOISOMERIC α-L-LNA: CONFORMATIONAL TUNING AND HIGH-AFFINITY RECOGNITION OF DNA/RNA TARGETS | Full Text | References | PDF (120.7 KB)
  • 183 Views
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Article
THE ROLE OF ANTISENSE OLIGONUCLEOTIDES IN THE WAVE OF GENOMIC INFORMATION
Brenda F. Baker
Pages: 397-399
Published online: 07 Feb 2007
AbstractforTHE ROLE OF ANTISENSE OLIGONUCLEOTIDES IN THE WAVE OF GENOMIC INFORMATION | Full Text | References | PDF (61.5 KB)
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Article
TELOMERASE INHIBITORS – OLIGONUCLEOTIDE PHOSPHORAMIDATES AS POTENTIAL THERAPEUTIC AGENTS
S. Gryaznov, K. Pongracz, T. Matray, R. Schultz, R. Pruzan, J. Aimi, A. Chin, C. Harley, B. Shea-Herbert, J. Shay, Y. Oshima, A. Asai & Y. Yamashita
Pages: 401-410
Published online: 07 Feb 2007
AbstractforTELOMERASE INHIBITORS – OLIGONUCLEOTIDE PHOSPHORAMIDATES AS POTENTIAL THERAPEUTIC AGENTS | Full Text | References | PDF (149.9 KB)
  • 146 Views
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Article
DNA TRIPLE-HELIX FORMATION AT PYRIMIDINE-PURINE INVERSION SITES
Serge P. Parel, Judith Marfurt & Christian J. Leumann
Pages: 411-417
Published online: 07 Feb 2007
AbstractforDNA TRIPLE-HELIX FORMATION AT PYRIMIDINE-PURINE INVERSION SITES | Full Text | References | PDF (188.7 KB)
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Article
PNA-RELATED OLIGONUCLEOTIDE MIMICS AND THEIR EVALUATION FOR NUCLEIC ACID HYBRIDIZATION STUDIES AND ANALYSIS
V. Efimov, M. Choob, A. Buryakova, D. Phelan & O. Chakhmakhcheva
Pages: 419-428
Published online: 07 Feb 2007
AbstractforPNA-RELATED OLIGONUCLEOTIDE MIMICS AND THEIR EVALUATION FOR NUCLEIC ACID HYBRIDIZATION STUDIES AND ANALYSIS | Full Text | References | PDF (308.8 KB)
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Article
PROPERTIES OF ARABINONUCLEIC ACIDS (ANA & 20′F-ANA): IMPLICATIONS FOR THE DESIGN OF ANTISENSE THERAPEUTICS THAT INVOKE RNASE H CLEAVAGE OF RNA
M. J. Damha, A. M. Noronha, C. J. Wilds, J.-F. Trempe, A. Denisov, R. T. Pon & K. Gehring
Pages: 429-440
Published online: 07 Feb 2007
AbstractforPROPERTIES OF ARABINONUCLEIC ACIDS (ANA & 20′F-ANA): IMPLICATIONS FOR THE DESIGN OF ANTISENSE THERAPEUTICS THAT INVOKE RNASE H CLEAVAGE OF RNA | Full Text | References | PDF (317.9 KB)
  • 233 Views
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Article
RNA AND N3′ → P5′ KISSING APTAMERS TARGETED TO THE TRANS-ACTIVATION RESPONSIVE (TAR) RNA OF THE HUMAN IMMUNODEFICIENCY VIRUS-1
Fabien Darfeuille, Christian Cazenave, Sergei Gryaznov, Frédéric Ducongé, Carmelo Di Primo & Jean-Jacques Toulmé
Pages: 441-449
Published online: 07 Feb 2007
AbstractforRNA AND N3′ → P5′ KISSING APTAMERS TARGETED TO THE TRANS-ACTIVATION RESPONSIVE (TAR) RNA OF THE HUMAN IMMUNODEFICIENCY VIRUS-1 | Full Text | References | PDF (127 KB)
  • 74 Views
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Article
INHIBITION OF (CYTOSINE C5)-METHYLTRANSFERASE BY OLIGONUCLEOTIDES CONTAINING FLEXIBLE (CYCLOPENTANE) AND CONFORMATIONALLY CONSTRAINED (BICYCLO[3.1.0]HEXANE) ABASIC SITES
Victor E. Marquez, Peiyuan Wang, Marc C. Nicklaus, Martin Maier, Muthiah Manoharan, Judith K. Christman, Nilesh K. Banavali & Alexander D. Mackerell Jr.
Pages: 451-459
Published online: 07 Feb 2007
AbstractforINHIBITION OF (CYTOSINE C5)-METHYLTRANSFERASE BY OLIGONUCLEOTIDES CONTAINING FLEXIBLE (CYCLOPENTANE) AND CONFORMATIONALLY CONSTRAINED (BICYCLO[3.1.0]HEXANE) ABASIC SITES | Full Text | References | PDF (135.9 KB)
  • 118 Views
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Article
INTRACELLULAR Ca2+-MOBILIZING ADENINE NUCLEOTIDES. SYNTHESIS AND BIOLOGICAL ACTIVITY OF CYCLIC ADP-CARBOCYCLIC-RIBOSE AND C-GLYCOSIDIC ANALOG OF ADENOPHOSTIN A
Satoshi Shuto, Masayoshi Fukuoka, Hiroshi Abe & Akira Matsuda
Pages: 461-470
Published online: 07 Feb 2007
AbstractforINTRACELLULAR Ca2+-MOBILIZING ADENINE NUCLEOTIDES. SYNTHESIS AND BIOLOGICAL ACTIVITY OF CYCLIC ADP-CARBOCYCLIC-RIBOSE AND C-GLYCOSIDIC ANALOG OF ADENOPHOSTIN A | Full Text | References | PDF (152.3 KB)
  • 52 Views
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Article
OLIGONUCLEOTIDE ANALOGUE INTERFERENCE WITH THE HIV-1 TAT PROTEIN-TAR RNA INTERACTION
Andrey Arzumanov, Andrew P. Walsh, Xiaohai Liu, Vivek K. Rajwanshi, Jesper Wengel & Michael J. Gait
Pages: 471-480
Published online: 07 Feb 2007
AbstractforOLIGONUCLEOTIDE ANALOGUE INTERFERENCE WITH THE HIV-1 TAT PROTEIN-TAR RNA INTERACTION | Full Text | References | PDF (288.4 KB)
  • 94 Views
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Article
6-OXOCYTIDINE CONTAINING OLIGONUCLEOTIDES INHIBIT THE HIV-1 INTEGRASE IN VITRO
P. Brodin, M. Pinskaya, U. Parsch, J. Bischerour, H. Leh, E. Romanova, J. W. Engels, M. Gottikh & J. F. Mouscadet
Pages: 481-486
Published online: 07 Feb 2007
Abstractfor6-OXOCYTIDINE CONTAINING OLIGONUCLEOTIDES INHIBIT THE HIV-1 INTEGRASE IN VITRO | Full Text | References | PDF (90.9 KB)
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Article
ZIDOVUDINE (AZT) RESISTANCE IN H9 CELLS DUE TO DECREASED TK EXPRESSION IS ASSOCIATED WITH HYPERMETHYLATION OF TK GENE
B. Gröschel, G. Höver, H. W. Doerr & J. Cinatl Jr.
Pages: 487-492
Published online: 07 Feb 2007
AbstractforZIDOVUDINE (AZT) RESISTANCE IN H9 CELLS DUE TO DECREASED TK EXPRESSION IS ASSOCIATED WITH HYPERMETHYLATION OF TK GENE | Full Text | References | PDF (152.3 KB)
  • 36 Views
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Article
STRUCTURAL, DYNAMIC, AND ENZYMATIC PROPERTIES OF MIXED α/β-OLIGONUCLEOTIDES CONTAINING POLARITY REVERSALS
M. W. Germann, J. M. Aramini, B. W. Kalisch & J. H. van de Sande
Pages: 493-499
Published online: 07 Feb 2007
AbstractforSTRUCTURAL, DYNAMIC, AND ENZYMATIC PROPERTIES OF MIXED α/β-OLIGONUCLEOTIDES CONTAINING POLARITY REVERSALS | Full Text | References | PDF (266 KB)
  • 53 Views
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Article
ANALOGS OF GUANINE NUCLEOSIDE TRIPHOSPHATES FOR SEQUENCING APPLICATIONS
Mark G. McDougall, Lei Sun, Inna Livshin, Louis P. Hosta, Bernard F. McArdle, Sui-Bi Samols, Carl W. Fuller & Shiv Kumar
Pages: 501-506
Published online: 07 Feb 2007
AbstractforANALOGS OF GUANINE NUCLEOSIDE TRIPHOSPHATES FOR SEQUENCING APPLICATIONS | Full Text | References | PDF (93.5 KB)
  • 139 Views
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Article
2′-MODIFIED OLIGONUCLEOTIDES FROM METHOXYOXALAMIDO AND SUCCINIMIDO PRECURSORS: SYNTHESIS, PROPERTIES, AND APPLICATIONS
N. Polushin, A. Malykh, O. Malykh, M. Zenkova, N. Chumakova, V. Vlassov & S. Kozyavkin
Pages: 507-514
Published online: 07 Feb 2007
Abstractfor2′-MODIFIED OLIGONUCLEOTIDES FROM METHOXYOXALAMIDO AND SUCCINIMIDO PRECURSORS: SYNTHESIS, PROPERTIES, AND APPLICATIONS | Full Text | References | PDF (204.7 KB)
  • 47 Views
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Article
ENHANCED INHIBITION OF HIV-1 REPLICATION IN MACROPHAGES BY ANTISENSE OLIGONUCLEOTIDES, RIBOZYMES AND ACYCLIC NUCLEOSIDE PHOSPHONATE ANALOGS DELIVERED IN pH-SENSITIVE LIPOSOMES
N. Düzgünes, S. Simões, V. Slepushkin, E. Pretzer, J. J. Rossi, E. De Clercq, V. P. Antao, M. L. Collins & M. C. Pedroso de Lima
Pages: 515-523
Published online: 07 Feb 2007
AbstractforENHANCED INHIBITION OF HIV-1 REPLICATION IN MACROPHAGES BY ANTISENSE OLIGONUCLEOTIDES, RIBOZYMES AND ACYCLIC NUCLEOSIDE PHOSPHONATE ANALOGS DELIVERED IN pH-SENSITIVE LIPOSOMES | Full Text | References | PDF (135.4 KB)
  • 80 Views
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Article
PHOTOLITHOGRAPHIC SYNTHESIS OF HIGH-DENSITY OLIGONUCLEOTIDE PROBE ARRAYS
Anthony D. Barone, Jody E. Beecher, Paul A. Bury, Chuan Chen, Tina Doede, Jacqueline A. Fidanza & Glenn H. McGall
Pages: 525-531
Published online: 07 Feb 2007
AbstractforPHOTOLITHOGRAPHIC SYNTHESIS OF HIGH-DENSITY OLIGONUCLEOTIDE PROBE ARRAYS | Full Text | References | PDF (301.1 KB)
  • 252 Views
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Article
HIGH CAPACITY SUBSTRATES AS A PLATFORM FOR A DNA PROBE ARRAY GENOTYPING ASSAY
Jacqueline Fidanza, Marc Glazer, Daniel Mutnick, Glenn McGall & Curt Frank
Pages: 533-538
Published online: 07 Feb 2007
AbstractforHIGH CAPACITY SUBSTRATES AS A PLATFORM FOR A DNA PROBE ARRAY GENOTYPING ASSAY | Full Text | References | PDF (168.5 KB)
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Article
SYNTHESIS OF PEPTIDE-OLIGONUCLEOTIDE PHOSPHOROTHIOATE CONJUGATES BY CONVERGENT OR STEPWISE SOLID-PHASE STRATEGIES
Maxim Antopolsky & Alex Azhayev
Pages: 539-550
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF PEPTIDE-OLIGONUCLEOTIDE PHOSPHOROTHIOATE CONJUGATES BY CONVERGENT OR STEPWISE SOLID-PHASE STRATEGIES | Full Text | References | PDF (298.5 KB)
  • 91 Views
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Article
NOVEL CLASS OF DNA BINDING MOTIFS BASED ON BISTETRAHYDROFURAN AND BISFURAN SKELETON WITH LONG ALKYL CHAINS
Shigeki Sasaki, Takayuki Shibata, Hidemine Torigoe, Yosinori Shibata & Minoru Maeda
Pages: 551-558
Published online: 07 Feb 2007
AbstractforNOVEL CLASS OF DNA BINDING MOTIFS BASED ON BISTETRAHYDROFURAN AND BISFURAN SKELETON WITH LONG ALKYL CHAINS | Full Text | References | PDF (152.7 KB)
  • 65 Views
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Article
COVALENT MODIFICATION AND SURFACE IMMOBILIZATION OF NUCLEIC ACIDS VIA THE DIELS-ALDER BIOCONJUGATION METHOD
Gregory M. Husar, Dominick J. Anziano, Michael Leuck & David P. Sebesta
Pages: 559-566
Published online: 07 Feb 2007
AbstractforCOVALENT MODIFICATION AND SURFACE IMMOBILIZATION OF NUCLEIC ACIDS VIA THE DIELS-ALDER BIOCONJUGATION METHOD | Full Text | References | PDF (118 KB)
  • 182 Views
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Article
A CASE STUDY: OLIGONUCLEOTIDE PURIFICATION FROM GRAM TO HUNDRED GRAM SCALE
Ranjit R. Deshmukh, Kjell-Ove Eriksson, Peter Moore, Douglas L. Cole & Yogesh S. Sanghvi
Pages: 567-576
Published online: 07 Feb 2007
AbstractforA CASE STUDY: OLIGONUCLEOTIDE PURIFICATION FROM GRAM TO HUNDRED GRAM SCALE | Full Text | References | PDF (99.2 KB)
  • 246 Views
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Article
8-AZA-7-DEAZAADENINE AND 7-DEAZAGUANINE: SYNTHESIS AND PROPERTIES OF NUCLEOSIDES AND OLIGONUCLEOTIDES WITH NUCLEOBASES LINKED AT POSITION-8
F. Seela & H. Debelak
Pages: 577-585
Published online: 07 Feb 2007
Abstractfor8-AZA-7-DEAZAADENINE AND 7-DEAZAGUANINE: SYNTHESIS AND PROPERTIES OF NUCLEOSIDES AND OLIGONUCLEOTIDES WITH NUCLEOBASES LINKED AT POSITION-8 | Full Text | References | PDF (130.9 KB)
  • 94 Views
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Article
SYNTHESIS OF NEW CLASSES OF BORON-CONTAINING NUCLEOTIDES
Jinlai Lin & Barbara Ramsay Shaw
Pages: 587-596
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF NEW CLASSES OF BORON-CONTAINING NUCLEOTIDES | Full Text | References | PDF (144 KB)
  • 127 Views
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Article
ANTI-HBV SPECIFIC β-L-2′-DEOXYNUCLEOSIDES
Martin L. Bryant, Edward G. Bridges, Laurent Placidi, Abdesslem Faraj, Anna-Giulia Loi, Claire Pierra, David Dukhan, Gilles Gosselin, Jean-Louis Imbach, Brenda Hernandez, Amy Juodawlkis, Bud Tennant, Brent Korba, Paul Cote, Erika Cretton-Scott, Raymond F. Schinazi & Jean-Pierre Sommadossi
Pages: 597-607
Published online: 07 Feb 2007
AbstractforANTI-HBV SPECIFIC β-L-2′-DEOXYNUCLEOSIDES | Full Text | References | PDF (124.9 KB)
  • 137 Views
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Article
1-(3-C-ETHYNYL-β-D-RIBO-PENTOFURANOSYL)CYTOSINE (ECYD, TAS-106)1: ANTITUMOR EFFECT AND MECHANISM OF ACTION
Atsushi Azuma, Akira Matsuda, Takuma Sasaki & Masakazu Fukushima
Pages: 609-619
Published online: 07 Feb 2007
Abstractfor1-(3-C-ETHYNYL-β-D-RIBO-PENTOFURANOSYL)CYTOSINE (ECYD, TAS-106)1: ANTITUMOR EFFECT AND MECHANISM OF ACTION | Full Text | References | PDF (130.8 KB)
  • 79 Views
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Article
PRACTICAL SYNTHESIS, SEPARATION, AND STEREOCHEMICAL ASSIGNMENT OF THE PMPA PRO-DRUG GS-7340
H. Chapman, M. Kernan, E. Prisbe, J. Rohloff, M. Sparacino, T. Terhorst & R. Yu
Pages: 621-628
Published online: 07 Feb 2007
AbstractforPRACTICAL SYNTHESIS, SEPARATION, AND STEREOCHEMICAL ASSIGNMENT OF THE PMPA PRO-DRUG GS-7340 | Full Text | References | PDF (156.7 KB)
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Article
AN ASSAY SYSTEM TO DETECT THE SELECTIVE ADVANTAGE OF ANTI-HIV RIBOZYME EXPRESSING CD4+ T-LYMPHOCYTES
Stefan A. Klein, Christian Klebba & Joachim W. Engels
Pages: 629-634
Published online: 07 Feb 2007
AbstractforAN ASSAY SYSTEM TO DETECT THE SELECTIVE ADVANTAGE OF ANTI-HIV RIBOZYME EXPRESSING CD4+ T-LYMPHOCYTES | Full Text | References | PDF (92.4 KB)
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Article
TENOFOVIR (PMPA) IS LESS SUSCEPTIBLE TO PYROPHOSPHOROLYSIS AND NUCLEOTIDE-DEPENDENT CHAIN-TERMINATOR REMOVAL THAN ZIDOVUDINE OR STAVUDINE
Lisa K. Naeger, Nicolas A. Margot & Michael D. Miller
Pages: 635-639
Published online: 07 Feb 2007
AbstractforTENOFOVIR (PMPA) IS LESS SUSCEPTIBLE TO PYROPHOSPHOROLYSIS AND NUCLEOTIDE-DEPENDENT CHAIN-TERMINATOR REMOVAL THAN ZIDOVUDINE OR STAVUDINE | Full Text | References | PDF (155.5 KB)
  • 74 Views
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Article
HUMAN RENAL ORGANIC ANION TRANSPORTER 1 (hOAT1) AND ITS ROLE IN THE NEPHROTOXICITY OF ANTIVIRAL NUCLEOTIDE ANALOGS
Tomas Cihlar, Edmund S. Ho, Deborah C. Lin & Andrew S. Mulato
Pages: 641-648
Published online: 07 Feb 2007
AbstractforHUMAN RENAL ORGANIC ANION TRANSPORTER 1 (hOAT1) AND ITS ROLE IN THE NEPHROTOXICITY OF ANTIVIRAL NUCLEOTIDE ANALOGS | Full Text | References | PDF (123.1 KB)
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SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF SOME 4′-C-HYDROXYMETHYL-α- AND -β-D-ARABINO-PENTOFURANOSYL PYRIMIDINE NUCLEOSIDES
Jean-François Griffon, John A. Montgomery & John A. Secrist III
Pages: 649-652
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF SOME 4′-C-HYDROXYMETHYL-α- AND -β-D-ARABINO-PENTOFURANOSYL PYRIMIDINE NUCLEOSIDES | Full Text | References | PDF (100.5 KB)
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SYNTHESIS AND IN VITRO EVALUATION OF NOVEL ANTI-VARICELLA-ZOSTER VIRUS (VZV) NUCLEOSIDES
Antonella Carangio, Christopher McGuigan, D. Cahard, Graciela Andrei, Robert Snoeck, Erik De Clercq & Jan Balzarini
Pages: 653-656
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND IN VITRO EVALUATION OF NOVEL ANTI-VARICELLA-ZOSTER VIRUS (VZV) NUCLEOSIDES | Full Text | References | PDF (96.9 KB)
  • 111 Views
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STRUCTURE-ACTIVITY RELATIONSHIPS OF APIO NUCLEOSIDES AS POTENTIAL ANTIVIRAL AGENTS
Lak Shin Jeong, Hyung Ryong Moon, Jun Hee Hong, Su Jeong Yoo, Won Jun Choi, Hea Ok Kim, Hee Sung Ahn, Hye Woo Baek, Moon Woo Chun, Hee-Doo Kim, Jeongmin Kim & Jong-Ryoo Choi
Pages: 657-660
Published online: 07 Feb 2007
AbstractforSTRUCTURE-ACTIVITY RELATIONSHIPS OF APIO NUCLEOSIDES AS POTENTIAL ANTIVIRAL AGENTS | Full Text | References | PDF (107.1 KB)
  • 92 Views
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SYNTHESIS OF CARBOCYCLIC PHOSPHONONUCLEOSIDES
B. Legeret, Z. Sarakauskaite, F. Pradaux, Y. Saito, S. Tumkevicius & L. A. Agrofoglio
Pages: 661-664
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF CARBOCYCLIC PHOSPHONONUCLEOSIDES | Full Text | References | PDF (98.6 KB)
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SYNTHESIS AND ANTIVIRAL ACTIVITY OF D- AND L-2′-AZIDO-2′,3′-DIDEOXY-4′-THIOPYRIMIDINE AND PURINE NUCLEOSIDES
Lak Shin Jeong, Yun Ha Kim, Hea Ok Kim, Su Jeong Yoo, Yong Hee Park, Sook Hee Yeon, Moon Woo Chun & Hee-Doo Kim
Pages: 665-668
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTIVIRAL ACTIVITY OF D- AND L-2′-AZIDO-2′,3′-DIDEOXY-4′-THIOPYRIMIDINE AND PURINE NUCLEOSIDES | Full Text | References | PDF (109.6 KB)
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DNA SEQUENCE RECOGNITION BY NFκB p50 HOMODIMER: STRICT AND OBSCURE RECOGNITION SITES IN THE BINDING SEQUENCE
Atsushi Kittaka, Hiroaki Takayama, Masaaki Kurihara, Chikafumi Horii, Hiromichi Tanaka, Tadashi Miyasaka & Jun-ichiro Inoue
Pages: 669-672
Published online: 07 Feb 2007
AbstractforDNA SEQUENCE RECOGNITION BY NFκB p50 HOMODIMER: STRICT AND OBSCURE RECOGNITION SITES IN THE BINDING SEQUENCE | Full Text | References | PDF (139.3 KB)
  • 51 Views
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FOUR COLOR FRET DYE NUCLEOTIDE TERMINATORS FOR DNA SEQUENCING
T. Sudhakar Rao, Satyam Nampalli, Kate Lavrenov, Weihong Zhang, Haiguang Xiao, John Nelson & Shiv Kumar
Pages: 673-676
Published online: 07 Feb 2007
AbstractforFOUR COLOR FRET DYE NUCLEOTIDE TERMINATORS FOR DNA SEQUENCING | Full Text | References | PDF (158.6 KB)
  • 118 Views
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DESIGN AND SYNTHESIS OF NOVEL FLUOROCYCLOPROPANOID NUCLEOSIDES
Young Rang Lee, Ju-Hyun Park, Raok Jeon, Lak Shin Jeong, Moon Woo Chun & Hee-Doo Kim
Pages: 677-679
Published online: 07 Feb 2007
AbstractforDESIGN AND SYNTHESIS OF NOVEL FLUOROCYCLOPROPANOID NUCLEOSIDES | Full Text | References | PDF (78.1 KB)
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NOVEL NUCLEOSIDES WITH VINYL FLUORIDE OR VINYL BROMIDE MOIETY AS OPEN-CHAIN ANALOGS OF NEPLANOCIN A
Myung-Hee Choi, Chong-Kyo Lee, Lak Shin Jeong, Moon Woo Chun & Hee-Doo Kim
Pages: 681-684
Published online: 07 Feb 2007
AbstractforNOVEL NUCLEOSIDES WITH VINYL FLUORIDE OR VINYL BROMIDE MOIETY AS OPEN-CHAIN ANALOGS OF NEPLANOCIN A | Full Text | References | PDF (89.9 KB)
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MECHANISM OF INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE BY 5′-DEOXY-5′-S-ALLENYLTHIOADENOSINE AND 5′-DEOXY-5′-S-PROPYNYLTHIOADENOSINE
G. Guillerm, D. Guillerm & C. Witkowski-Vandenplas
Pages: 685-688
Published online: 07 Feb 2007
AbstractforMECHANISM OF INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE BY 5′-DEOXY-5′-S-ALLENYLTHIOADENOSINE AND 5′-DEOXY-5′-S-PROPYNYLTHIOADENOSINE | Full Text | References | PDF (85.9 KB)
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INACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE WITH FLUORINATED ANALOGS OF 2′- AND 3′-DEOXY-5′-METHYLTHIOADENOSINE
D. Guillerm, G. Guillerm & C. Witkowski-Vandenplas
Pages: 689-693
Published online: 07 Feb 2007
AbstractforINACTIVATION OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE WITH FLUORINATED ANALOGS OF 2′- AND 3′-DEOXY-5′-METHYLTHIOADENOSINE | Full Text | References | PDF (106.7 KB)
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SYNTHESIS AND BIOLOGICAL EVALUATION OF BORONATED NUCLEOSIDES FOR BORON NEUTRON CAPTURE THERAPY (BNCT) OF CANCER
W. Tjarks, J. Wang, S. Chandra, W. Ji, J. Zhuo, A. J. Lunato, C. Boyer, Q. Li, E. V. Usova, S. Eriksson, G. H. Morrison & G. Y. Cosquer
Pages: 695-698
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BIOLOGICAL EVALUATION OF BORONATED NUCLEOSIDES FOR BORON NEUTRON CAPTURE THERAPY (BNCT) OF CANCER | Full Text | References | PDF (111.4 KB)
  • 81 Views
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SYNTHESIS OF NOVEL 3′-DEOXY-3′-C-HYDROXYMETHYL NUCLEOSIDES WITH CONFORMATIONALLY RIGID SUGAR MOIETY AS POTENTIAL ANTIVIRAL AGENTS
Moon Woo Chun, Myung Jung Kim, Un Hee Jo, Joong Hyup Kim, Hee-Doo Kim & Lak Shin Jeong
Pages: 699-702
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF NOVEL 3′-DEOXY-3′-C-HYDROXYMETHYL NUCLEOSIDES WITH CONFORMATIONALLY RIGID SUGAR MOIETY AS POTENTIAL ANTIVIRAL AGENTS | Full Text | References | PDF (123.9 KB)
  • 77 Views
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SYNTHESIS OF NOVEL D- AND L-3′-DEOXY-3′-C-HYDROXYMETHYL NUCLEOSIDE WITH EXOCYCLIC METHYLENE AS POTENTIAL RIBONUCLEOTIDE REDUCTASE INHIBITOR
Moon Woo Chun, Myung Jung Kim, Un Hee Jo, Joong Hyup Kim, Hee-Doo Kim & Lak Shin Jeong
Pages: 703-706
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF NOVEL D- AND L-3′-DEOXY-3′-C-HYDROXYMETHYL NUCLEOSIDE WITH EXOCYCLIC METHYLENE AS POTENTIAL RIBONUCLEOTIDE REDUCTASE INHIBITOR | Full Text | References | PDF (101.1 KB)
  • 147 Views
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“SECOND GENERATION” OF TSAO COMPOUNDS DIRECTED AGAINST HIV-1 TSAO-RESISTANT STRAINS
E. Lobatón, S. Velázquez, M. J. Pérez-Pérez, M. L. Jimeno, A. San-Félix, E. De Clercq, J. Balzarini & M. J. Camarasa
Pages: 707-710
Published online: 07 Feb 2007
Abstractfor“SECOND GENERATION” OF TSAO COMPOUNDS DIRECTED AGAINST HIV-1 TSAO-RESISTANT STRAINS | Full Text | References | PDF (106.2 KB)
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4″-H-TSAO-T, A NOVEL PROTOTYPE IN THE HIV-1 SPECIFIC TSAO FAMILY
E. Lobatón, S. Velázquez, A. San-Félix, E. De Clercq, J. Balzarini & M. J. Camarasa
Pages: 711-714
Published online: 07 Feb 2007
Abstractfor4″-H-TSAO-T, A NOVEL PROTOTYPE IN THE HIV-1 SPECIFIC TSAO FAMILY | Full Text | References | PDF (93.5 KB)
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A NEW CLASS OF ANTI-HIV-1 OLIGONUCLEOTIDE TARGETED TO THE POLYPURINE TRACT OF VIRAL RNA
Takashi Hiratou, Naoko Miyano-Kurosaki, Hiroshi Gushima & Hiroshi Takaku
Pages: 715-718
Published online: 07 Feb 2007
AbstractforA NEW CLASS OF ANTI-HIV-1 OLIGONUCLEOTIDE TARGETED TO THE POLYPURINE TRACT OF VIRAL RNA | Full Text | References | PDF (85.8 KB)
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EFFECTIVE SUPPRESSION OF HIV-1 GENE EXPRESSION BY A MAMMALIAN tRNA 3′ PROCESSING ENDORIBONUCLEASE AND EXTERNAL GUIDE SEQUENCE OLIGOZYMES
Michiko Kitano, Jaco S. Barnor, Naoko Miyano-Kurosaki, Yumihiko Endo, Masakazu Yukita, Hiroaki Takeuchi, Yutaka Tamura, Kazuyuki Takai, Masayuki Nashimoto & Hiroshi Takaku
Pages: 719-722
Published online: 07 Feb 2007
AbstractforEFFECTIVE SUPPRESSION OF HIV-1 GENE EXPRESSION BY A MAMMALIAN tRNA 3′ PROCESSING ENDORIBONUCLEASE AND EXTERNAL GUIDE SEQUENCE OLIGOZYMES | Full Text | References | PDF (97.2 KB)
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INHIBITION OF HIV-1 REPLICATION BY THE CRE-LOXP HAMMERHEAD RIBOZYME
Yuichiro Habu, Naoko Miyano-Kurosaki, Hiroaki Takeuchi, Norihiko Matsumoto, Yutaka Tamura & Hiroshi Takaku
Pages: 723-726
Published online: 07 Feb 2007
AbstractforINHIBITION OF HIV-1 REPLICATION BY THE CRE-LOXP HAMMERHEAD RIBOZYME | Full Text | References | PDF (79 KB)
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(D)- AND (L)-CYCLOHEXENYL-G, A NEW CLASS OF ANTIVIRAL AGENTS: SYNTHESIS, CONFORMATIONAL ANALYSIS, MOLECULAR MODELING, AND BIOLOGICAL ACTIVITY
J. Wang, M. Froeyen, C. Hendrix, C. Andrei, R. Snoeck, E. Lescrinier, E. De Clercq & P. Herdewijn
Pages: 727-730
Published online: 07 Feb 2007
Abstractfor(D)- AND (L)-CYCLOHEXENYL-G, A NEW CLASS OF ANTIVIRAL AGENTS: SYNTHESIS, CONFORMATIONAL ANALYSIS, MOLECULAR MODELING, AND BIOLOGICAL ACTIVITY | Full Text | References | PDF (111.8 KB)
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SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIDIN-2-ONE NUCLEOSIDES
Caroline M. Huntley, Ann S. Cotterill, Jean-Yves Maillard, Jan Balzarini & Claire Simons
Pages: 731-733
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIDIN-2-ONE NUCLEOSIDES | Full Text | References | PDF (91.9 KB)
  • 70 Views
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ISONUCLEOSIDES INCORPORATING UNIVERSAL BASES
Vasu Nair, David S. Sosnouski & Qingming Zhu
Pages: 735-738
Published online: 07 Feb 2007
AbstractforISONUCLEOSIDES INCORPORATING UNIVERSAL BASES | Full Text | References | PDF (83.4 KB)
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A NEW PROCEDURE FOR THE PHOSPHORYLATION OF NUCLEOSIDES: APPLICATION TO THE DISCOVERY OF INHIBITORS OF HIV INTEGRASE
Vasu Nair & Michael Taktakishvili
Pages: 739-742
Published online: 07 Feb 2007
AbstractforA NEW PROCEDURE FOR THE PHOSPHORYLATION OF NUCLEOSIDES: APPLICATION TO THE DISCOVERY OF INHIBITORS OF HIV INTEGRASE | Full Text | References | PDF (80.5 KB)
  • 71 Views
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SYNTHESIS AND BIOLOGICAL ACTIVITY OF 4′-THIO-L-XYLOFURANOSYL NUCLEOSIDES
Kamal N. Tiwari, Lea Messini, John A. Montgomery & John A. Secrist III
Pages: 743-746
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BIOLOGICAL ACTIVITY OF 4′-THIO-L-XYLOFURANOSYL NUCLEOSIDES | Full Text | References | PDF (79.4 KB)
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SYNTHESIS AND BIOLOGICAL ACTIVITY OF 4′-C-HYDROXYMETHYL-2′-FLUORO-D-ARABINOFURANOSYLPURINE NUCLEOSIDES
A. T. Shortnacy-Fowler, K. N. Tiwari, J. A. Montgomery & J. A. Secrist III
Pages: 747-750
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BIOLOGICAL ACTIVITY OF 4′-C-HYDROXYMETHYL-2′-FLUORO-D-ARABINOFURANOSYLPURINE NUCLEOSIDES | Full Text | References | PDF (87.5 KB)
  • 127 Views
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SYNTHESIS AND STUDY OF A NEW SERIES OF PHOSPHORAMIDATE DERIVATIVES AS MONONUCLEOTIDE PRODRUGS
David Egron, Christian Périgaud, Gilles Gosselin, Anne-Marie Aubertin & Jean-Louis Imbach
Pages: 751-754
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND STUDY OF A NEW SERIES OF PHOSPHORAMIDATE DERIVATIVES AS MONONUCLEOTIDE PRODRUGS | Full Text | References | PDF (154.1 KB)
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SYNTHESIS AND ANTIVIRAL EVALUATION OF 3′-C-TRIFLUOROMETHYL NUCLEOSIDE DERIVATIVES BEARING ADENINE AS THE BASE
Frédéric Jeannot, Christophe Mathé & Gilles Gosselin
Pages: 755-758
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTIVIRAL EVALUATION OF 3′-C-TRIFLUOROMETHYL NUCLEOSIDE DERIVATIVES BEARING ADENINE AS THE BASE | Full Text | References | PDF (85 KB)
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SYNTHESIS OF 5-CHLORO-1-(2,3-DIDEOXY-3-FLUORO-β-D-GLYCERO-HEX-2-ENOPYRANOSE-4-ULOSYL)URACIL AS POTENTIAL ANTICANCER/ANTIVIRAL AGENT
Abdul R. Khan, Kimberly X. Mulligan*Abraham P. Ollapally
Pages: 759-762
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF 5-CHLORO-1-(2,3-DIDEOXY-3-FLUORO-β-D-GLYCERO-HEX-2-ENOPYRANOSE-4-ULOSYL)URACIL AS POTENTIAL ANTICANCER/ANTIVIRAL AGENT | Full Text | References | PDF (78.1 KB)
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BICYCLIC NUCLEOSIDE INHIBITORS OF VARICELLA-ZOSTER VIRUS (VZV): EFFECT OF TERMINAL UNSATURATION IN THE SIDE-CHAIN
Sheila Srinivasan, Christopher McGuigan, Graciela Andrei, Robert Snoeck, Erik De Clercq & Jan Balzarini
Pages: 763-766
Published online: 07 Feb 2007
AbstractforBICYCLIC NUCLEOSIDE INHIBITORS OF VARICELLA-ZOSTER VIRUS (VZV): EFFECT OF TERMINAL UNSATURATION IN THE SIDE-CHAIN | Full Text | References | PDF (92 KB)
  • 261 Views
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ANTI-HIV ACTIVITY OF NOVEL PHOSPHONATE DERIVATIVES OF AZT, d4T, AND ddA
A. G. Pokrovsky, T. R. Pronayeva, N. V. Fedyuk, E. A. Shirokova, A. L. Khandazhinskaya, N. B. Tarusova, I. L. Karpenko & A. A. Krayevsky
Pages: 767-769
Published online: 07 Feb 2007
AbstractforANTI-HIV ACTIVITY OF NOVEL PHOSPHONATE DERIVATIVES OF AZT, d4T, AND ddA | Full Text | References | PDF (71.5 KB)
  • 64 Views
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COUPLING OF 2,6-DISUBSTITUTED PURINES TO RIBOSE-MODIFIED SUGARS
S. Vittori, S. Costanzi, C. Lambertucci, R. Volpini & G. Cristalli
Pages: 771-774
Published online: 07 Feb 2007
AbstractforCOUPLING OF 2,6-DISUBSTITUTED PURINES TO RIBOSE-MODIFIED SUGARS | Full Text | References | PDF (89.7 KB)
  • 73 Views
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SYNTHETIC PROCEDURE FOR THE PREPARATION OF NOVEL POTENT AND SELECTIVE A3 ADENOSINE RECEPTOR RADIOLIGANDS
R. Volpini, S. Costanzi, C. Lambertucci, S. Vittori & G. Cristalli
Pages: 775-779
Published online: 07 Feb 2007
AbstractforSYNTHETIC PROCEDURE FOR THE PREPARATION OF NOVEL POTENT AND SELECTIVE A3 ADENOSINE RECEPTOR RADIOLIGANDS | Full Text | References | PDF (108.6 KB)
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INCREASED RNA AFFINITY OF HNA ANALOGUES BY INTRODUCING ALKOXY SUBSTITUENTS AT THE C-1 OR C-3 POSITION
A. Van Aerschot, M. Meldgaard, F. Volders, G. Schepers, J. Rozenski & P. Herdewijn
Pages: 781-784
Published online: 07 Feb 2007
AbstractforINCREASED RNA AFFINITY OF HNA ANALOGUES BY INTRODUCING ALKOXY SUBSTITUENTS AT THE C-1 OR C-3 POSITION | Full Text | References | PDF (81.6 KB)
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CYCLOHEXENE NUCLEIC ACIDS (CeNA) FORM STABLE DUPLEXES WITH RNA AND INDUCE RNASE H ACTIVITY
J. Wang, B. Verbeure, I. Luyten, M. Froeyen, C. Hendrix, H. Rosemeyer, F. Seela, A. Van Aerschot & P. Herdewijn
Pages: 785-788
Published online: 07 Feb 2007
AbstractforCYCLOHEXENE NUCLEIC ACIDS (CeNA) FORM STABLE DUPLEXES WITH RNA AND INDUCE RNASE H ACTIVITY | Full Text | References | PDF (85.1 KB)
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SYNTHESIS OF OLIGONUCLEOSIDE BORANOPHOSPHATES VIA AN H-PHOSPHONATE METHOD WITHOUT NUCLEOBASE PROTECTION
Dmitri S. Sergueev, Zinaida A. Sergueeva & Barbara Ramsay Shaw
Pages: 789-795
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF OLIGONUCLEOSIDE BORANOPHOSPHATES VIA AN H-PHOSPHONATE METHOD WITHOUT NUCLEOBASE PROTECTION | Full Text | References | PDF (106.7 KB)
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α-OLIGONUCLEOTIDES WITH ANIONIC PHOSPHODIESTER AND CATIONIC PHOSPHORAMIDATE LINKAGES ENHANCED STABILITY OF DNA TRIPLE HELIX
F. Ehrenmann, J.-J. Vasseur & F. Debart
Pages: 797-799
Published online: 07 Feb 2007
Abstractforα-OLIGONUCLEOTIDES WITH ANIONIC PHOSPHODIESTER AND CATIONIC PHOSPHORAMIDATE LINKAGES ENHANCED STABILITY OF DNA TRIPLE HELIX | Full Text | References | PDF (78.6 KB)
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A NEW “NATIVE LIGATION” PROCEDURE FOR PEPTIDE-OLIGONUCLEOTIDE CONJUGATION
Dmitry A. Stetsenko & Michael J. Gait
Pages: 801-804
Published online: 07 Feb 2007
AbstractforA NEW “NATIVE LIGATION” PROCEDURE FOR PEPTIDE-OLIGONUCLEOTIDE CONJUGATION | Full Text | References | PDF (132.2 KB)
  • 102 Views
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POLYIMIDAZOLE CONJUGATED OLIGONUCLEOTIDES REACH THE NUCLEUS OF HELA CELLS
François Morvan, C. Castex, E. Vivès & Jean-Louis Imbach
Pages: 805-808
Published online: 07 Feb 2007
AbstractforPOLYIMIDAZOLE CONJUGATED OLIGONUCLEOTIDES REACH THE NUCLEUS OF HELA CELLS | Full Text | References | PDF (169.2 KB)
  • 58 Views
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RECOGNITION OF DNA BY STRAND INVASION WITH OLIGONUCLEOTIDE-SPERMINE CONJUGATES
Pierre F. Potier & Jean-Paul Behr
Pages: 809-813
Published online: 07 Feb 2007
AbstractforRECOGNITION OF DNA BY STRAND INVASION WITH OLIGONUCLEOTIDE-SPERMINE CONJUGATES | Full Text | References | PDF (194.8 KB)
  • 61 Views
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STACKING AND STABILITY OF RNA DUPLEXES CONTAINING FLUOROBENZENE AND FLUOROBENZIMIDAZOLE NUCLEOSIDES
Jörg Parsch & Joachim W. Engels
Pages: 815-818
Published online: 07 Feb 2007
AbstractforSTACKING AND STABILITY OF RNA DUPLEXES CONTAINING FLUOROBENZENE AND FLUOROBENZIMIDAZOLE NUCLEOSIDES | Full Text | References | PDF (81.6 KB)
  • 37 Views
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OLIGONUCLEOTIDES WITH ISOPOLAR PHOSPHONATE INTERNUCLEOTIDE LINKAGE: A NEW PERSPECTIVE FOR ANTISENSE COMPOUNDS?
D. Rejman, J. Snášel, R. Liboska, Z. Točík, O. Pačes, Š. Králíková, M. Rinnová, P. Koiš & I. Rosenberg
Pages: 819-823
Published online: 07 Feb 2007
AbstractforOLIGONUCLEOTIDES WITH ISOPOLAR PHOSPHONATE INTERNUCLEOTIDE LINKAGE: A NEW PERSPECTIVE FOR ANTISENSE COMPOUNDS? | Full Text | References | PDF (104.7 KB)
  • 74 Views
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SYNTHESIS AND EVALUATION OF α-LNA
Nanna K. Christensen, Jakob K. Dalskov & Paul Nielsen
Pages: 825-828
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND EVALUATION OF α-LNA | Full Text | References | PDF (110.9 KB)
  • 72 Views
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ANTISENSE PROPERTIES OF 2′-O-DIMETHYLAMINOOXYETHYL (2′-O-DMAOE) OLIGONUCLEOTIDES
Thazha P. Prakash, Andrew M. Kawasaki, Joseph F. Johnston, Mark J. Graham, Thomas P. Condon & Muthiah Manoharan
Pages: 829-832
Published online: 07 Feb 2007
AbstractforANTISENSE PROPERTIES OF 2′-O-DIMETHYLAMINOOXYETHYL (2′-O-DMAOE) OLIGONUCLEOTIDES | Full Text | References | PDF (83.7 KB)
  • 35 Views
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RAPID RNA CLEAVAGE USING AN ANTISENSE SYSTEM WITH TWO TERPYRIDINE · Cu(II) COMPLEXES
Hideo Inoue, Takako Furukawa, Takashi Tamura, Akihiro Kamada & Eiko Ohtsuka
Pages: 833-835
Published online: 07 Feb 2007
AbstractforRAPID RNA CLEAVAGE USING AN ANTISENSE SYSTEM WITH TWO TERPYRIDINE · Cu(II) COMPLEXES | Full Text | References | PDF (74.7 KB)
  • 28 Views
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UNNATURAL ENANTIOMERS OF 5-AZACYTIDINE ANALOGUES: SYNTHESES AND ENZYMATIC PROPERTIES
G. Gaubert, G. Gosselin, S. Eriksson, A. Vita & G. Maury
Pages: 837-840
Published online: 07 Feb 2007
AbstractforUNNATURAL ENANTIOMERS OF 5-AZACYTIDINE ANALOGUES: SYNTHESES AND ENZYMATIC PROPERTIES | Full Text | References | PDF (79.4 KB)
  • 83 Views
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A CODE RELATING SEQUENCE TO STRUCTURE IN NUCLEIC ACIDS
Mieczysław Remin
Pages: 841-846
Published online: 07 Feb 2007
AbstractforA CODE RELATING SEQUENCE TO STRUCTURE IN NUCLEIC ACIDS | Full Text | References | PDF (93.2 KB)
  • 17 Views
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INTERACTION OF LNA OLIGONUCLEOTIDES WITH MDR1 PROMOTER
E. L. Chernolovskaya, A. A. Koshkin & V. V. Vlassov
Pages: 847-850
Published online: 07 Feb 2007
AbstractforINTERACTION OF LNA OLIGONUCLEOTIDES WITH MDR1 PROMOTER | Full Text | References | PDF (203 KB)
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Article
Cu2+-DEPENDENT DNA-CLEAVING ACTIVITY OF ARENES
O. A. Koval, E. L. Chernolovskaya, V. V. Litvak & V. V. Vlassov
Pages: 851-854
Published online: 07 Feb 2007
AbstractforCu2+-DEPENDENT DNA-CLEAVING ACTIVITY OF ARENES | Full Text | References | PDF (131.7 KB)
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Article
SIMULTANEOUS HPLC ANALYSIS OF HYDROPHOBIC PRODRUGS AND THEIR HYDROPHILIC METABOLITES IN BIOLOGICAL MEDIA WITHOUT SAMPLE PREPARATION. APPLICATION TO THE BIOTRANSFORMATION STUDIES OF PRONUCLEOTIDES DERIVED FROM 5-FLUOROURACIL
G. Coussot, I. Lefebvre-Tournier, L. Hollecker, G. Gosselin, J.-L. Imbach & A. Pompon
Pages: 855-858
Published online: 07 Feb 2007
AbstractforSIMULTANEOUS HPLC ANALYSIS OF HYDROPHOBIC PRODRUGS AND THEIR HYDROPHILIC METABOLITES IN BIOLOGICAL MEDIA WITHOUT SAMPLE PREPARATION. APPLICATION TO THE BIOTRANSFORMATION STUDIES OF PRONUCLEOTIDES DERIVED FROM 5-FLUOROURACIL | Full Text | References | PDF (80.4 KB)
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Article
INTERACTION OF OLIGONUCLEOTIDES WITH CELLULAR PROTEINS
P. Laktionov, B. Chelobanov, E. Rykova & V. Vlassov
Pages: 859-862
Published online: 07 Feb 2007
AbstractforINTERACTION OF OLIGONUCLEOTIDES WITH CELLULAR PROTEINS | Full Text | References | PDF (138 KB)
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Article
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IS RESPONSIBLE FOR INTRANUCLEAR LOCALIZATION OF SOME OLIGONUCLEOTIDES
V. Tomasi, P. P. Laktionov, A. V. Bryksin, N. V. Volod'ko, C. Griffoni, E. Y. Rykova, E. Spisni, R. Kraft & V. V. Vlassov
Pages: 863-867
Published online: 07 Feb 2007
AbstractforGLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IS RESPONSIBLE FOR INTRANUCLEAR LOCALIZATION OF SOME OLIGONUCLEOTIDES | Full Text | References | PDF (228.1 KB)
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5-PROPYNYLPYRIMIDINE NUCLEOSIDE DERIVATIVES: RATIONALLY DESIGNED MECHANISM-BASED INACTIVATORS OF THYMIDYLATE SYNTHASE
Thomas I. Kalman, Zhe Nie & Ashwini Kamat
Pages: 869-871
Published online: 07 Feb 2007
Abstractfor5-PROPYNYLPYRIMIDINE NUCLEOSIDE DERIVATIVES: RATIONALLY DESIGNED MECHANISM-BASED INACTIVATORS OF THYMIDYLATE SYNTHASE | Full Text | References | PDF (85.1 KB)
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INHIBITION OF IN VITRO PRE-mRNA SPLICING IN S. CEREVISIAE BY BRANCHED OLIGONUCLEOTIDES
S. Carriero, R. S. Braich, R. H. E. Hudson, D. Anglin, J. D. Friesen & M. J. Damha
Pages: 873-877
Published online: 07 Feb 2007
AbstractforINHIBITION OF IN VITRO PRE-mRNA SPLICING IN S. CEREVISIAE BY BRANCHED OLIGONUCLEOTIDES | Full Text | References | PDF (194.4 KB)
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Article
SYNTHESIS OF 3′-THIOAMIDO-MODIFIED 3′-DEOXYTHYMIDINE-5′-TRIPHOSPHATES AND THEIR USE AS CHAIN TERMINATORS IN SANGER-DNA SEQUENCING
K. Schwarzer, C. Wojczewski & J. W. Engels
Pages: 879-882
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF 3′-THIOAMIDO-MODIFIED 3′-DEOXYTHYMIDINE-5′-TRIPHOSPHATES AND THEIR USE AS CHAIN TERMINATORS IN SANGER-DNA SEQUENCING | Full Text | References | PDF (77.4 KB)
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Article
NOVEL PROPARGYLAMINE-LINKED NUCLEOSIDES FOR HIGH THROUGHPUT SNP GENOTYPING BY MALDI-TOF MS
Thomas Wenzel, Thomas Fröhlich, Kathrin Strassburger, Susann Richter, Jacqueline Bimmler, Constance Franke, Isabell Thomas & Markus Kostrzewa
Pages: 883-887
Published online: 07 Feb 2007
AbstractforNOVEL PROPARGYLAMINE-LINKED NUCLEOSIDES FOR HIGH THROUGHPUT SNP GENOTYPING BY MALDI-TOF MS | Full Text | References | PDF (93.9 KB)
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Article
LIPOPLEX-MEDIATED STABLE GENE TRANSFER INTO HeLa CELLS
Moganavelli Singh, Sharda Balram & Mario Ariatti
Pages: 889-891
Published online: 07 Feb 2007
AbstractforLIPOPLEX-MEDIATED STABLE GENE TRANSFER INTO HeLa CELLS | Full Text | References | PDF (105 KB)
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ROLLING CIRCLE AMPLIFICATION FOR SCORING SINGLE NUCLEOTIDE POLYMORPHISMS
A. Rösler, L. Bailey, S. Jones, J. Briggs, S. Cuss, I. Horsey, M. Kenrick, S. Kingsmore, L. Kent, J. Pickering, T. Knott, E. Shipstone & G. Scozzafava
Pages: 893-894
Published online: 07 Feb 2007
AbstractforROLLING CIRCLE AMPLIFICATION FOR SCORING SINGLE NUCLEOTIDE POLYMORPHISMS | Full Text | References | PDF (62.3 KB)
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Article
THE USE OF (OLIGONUCLEOTIDE-MALEIC ANHYDRIDE COPOLYMER) CONJUGATES IN NUCLEIC ACID DIAGNOSTIC ASSAYS: EFFECT OF THE NUMBER OF OLIGONUCLEOTIDES PER POLYMER ON TEST SENSITIVITY IMPROVEMENT
C. Minard-Basquin, C. Chaix & C. Pichot
Pages: 895-899
Published online: 07 Feb 2007
AbstractforTHE USE OF (OLIGONUCLEOTIDE-MALEIC ANHYDRIDE COPOLYMER) CONJUGATES IN NUCLEIC ACID DIAGNOSTIC ASSAYS: EFFECT OF THE NUMBER OF OLIGONUCLEOTIDES PER POLYMER ON TEST SENSITIVITY IMPROVEMENT | Full Text | References | PDF (124.3 KB)
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Article
SECO C-NUCLEOSIDE ANALOGS OF THE 1,2,4-TRIAZOLE
El Sayed H. El Ashry & Laila F. Awad
Pages: 901-902
Published online: 07 Feb 2007
AbstractforSECO C-NUCLEOSIDE ANALOGS OF THE 1,2,4-TRIAZOLE | Full Text | References | PDF (74.6 KB)
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2′-O-MODIFIED OLIGORIBONUCLEOTIDES WITH TERMINAL 3′-3′-INTERNUCLEOTIDE LINKAGE AND THEIR DERIVATIVES
D. Novopashina, M. Kuznetsova & A. Venyaminova
Pages: 903-907
Published online: 07 Feb 2007
Abstractfor2′-O-MODIFIED OLIGORIBONUCLEOTIDES WITH TERMINAL 3′-3′-INTERNUCLEOTIDE LINKAGE AND THEIR DERIVATIVES | Full Text | References | PDF (237.1 KB)
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Article
DESIGN AND SIMPLE ROUTES OF SYNTHESIS OF OLIGONUCLEOTIDE CONJUGATES FOR STUDIES OF DNA TRIPLE HELIX FORMATION
G. N. Grimm, A. S. Boutorine, P. Lincoln & C. Hélène
Pages: 909-914
Published online: 07 Feb 2007
AbstractforDESIGN AND SIMPLE ROUTES OF SYNTHESIS OF OLIGONUCLEOTIDE CONJUGATES FOR STUDIES OF DNA TRIPLE HELIX FORMATION | Full Text | References | PDF (197.2 KB)
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SITE-DIRECTED ALKYLATION TO CYTIDINE WITHIN DUPLEX BY THE OLIGONUCLEOTIDES CONTAINING FUNCTIONAL NUCLEOBASES
Fumi Nagatsugi, Takeshi Kawasaki, Natsuko Tokuda, Minoru Maeda & Shigeki Sasaki
Pages: 915-919
Published online: 07 Feb 2007
AbstractforSITE-DIRECTED ALKYLATION TO CYTIDINE WITHIN DUPLEX BY THE OLIGONUCLEOTIDES CONTAINING FUNCTIONAL NUCLEOBASES | Full Text | References | PDF (90.1 KB)
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Article
SYNTHESIS OF SOME 2′- AND 3′-FLUOROALKYL SUBSTITUTED NUCLEOSIDES AND OLIGONUCLEOTIDES
Pawel J. Serafinowski, Catherine A. Brown & Colin L. Barnes
Pages: 921-925
Published online: 07 Feb 2007
First Page PreviewforSYNTHESIS OF SOME 2′- AND 3′-FLUOROALKYL SUBSTITUTED NUCLEOSIDES AND OLIGONUCLEOTIDES | Full Text | References | PDF (106.8 KB)
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SYNTHESIS AND PHOTOCHEMICAL BEHAVIOUR OF A T-T DIMER CONTAINING AN AMIDE LINKAGE
Martial Thomas, Pascale Clivio, Dominique Guillaume & Jean-Louis Fourrey
Pages: 927-929
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND PHOTOCHEMICAL BEHAVIOUR OF A T-T DIMER CONTAINING AN AMIDE LINKAGE | Full Text | References | PDF (89.3 KB)
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BENZYL-FUNCTIONALIZED cycloSal-d4T MONOPHOSPHATES
J. Renze, M. Plath, C. Ducho, J. Balzarini, E. De Clercq & C. Meier
Pages: 931-934
Published online: 07 Feb 2007
AbstractforBENZYL-FUNCTIONALIZED cycloSal-d4T MONOPHOSPHATES | Full Text | References | PDF (87.2 KB)
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SYNTHESIS OF N2-ALKYLGUANOSINE USING MITSUNOBU REACTION AS A KEY STEP
Tokumi Maruyama, Aya Yorikane & Shigetada Kozai
Pages: 935-936
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF N2-ALKYLGUANOSINE USING MITSUNOBU REACTION AS A KEY STEP | Full Text | References | PDF (72.4 KB)
  • 81 Views
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EFFICIENT SYNTHESIS OF D-[1′-13C]-RIBONUCLEOSIDES FOR INCORPORATION INTO OLIGO-RNA
Y. Saito, A. Nyilas & L. A. Agrofoglio
Pages: 937-940
Published online: 07 Feb 2007
AbstractforEFFICIENT SYNTHESIS OF D-[1′-13C]-RIBONUCLEOSIDES FOR INCORPORATION INTO OLIGO-RNA | Full Text | References | PDF (87.3 KB)
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BORANE-AMINE COMPLEXES - VERSATILE REAGENTS IN THE CHEMISTRY OF NUCLEIC ACIDS AND THEIR ANALOGS
Zinaida A. Sergueeva, Dmitri S. Sergueev & Barbara Ramsay Shaw
Pages: 941-945
Published online: 07 Feb 2007
AbstractforBORANE-AMINE COMPLEXES - VERSATILE REAGENTS IN THE CHEMISTRY OF NUCLEIC ACIDS AND THEIR ANALOGS | Full Text | References | PDF (89.8 KB)
  • 277 Views
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PRO-OLIGONUCLEOTIDE SYNTHESIS USING ALLYL AND ALLYLOXYCARBONYL PROTECTIONS: DIRECT MALDI-TOF MS ANALYSIS ON SOLID SUPPORT
N. Spinelli, J.-J. Vasseur, Y. Hayakawa & J.-L. Imbach
Pages: 947-950
Published online: 07 Feb 2007
AbstractforPRO-OLIGONUCLEOTIDE SYNTHESIS USING ALLYL AND ALLYLOXYCARBONYL PROTECTIONS: DIRECT MALDI-TOF MS ANALYSIS ON SOLID SUPPORT | Full Text | References | PDF (116 KB)
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STEP-BY-STEP CONTROL BY MALDI-TOF MS OF AN OLIGONUCLEOTIDE SYNTHESIS ON STANDARD CPG SOLID-SUPPORT
A. Meyer, F. Debart, J.-L. Imbach & J.-J. Vasseur
Pages: 951-954
Published online: 07 Feb 2007
AbstractforSTEP-BY-STEP CONTROL BY MALDI-TOF MS OF AN OLIGONUCLEOTIDE SYNTHESIS ON STANDARD CPG SOLID-SUPPORT | Full Text | References | PDF (97.7 KB)
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SYNTHESIS OF SOME ACYCLONUCLEOSIDES α-(PYRAZOLO[3,4-d]PYRIMIDIN-4-YLTHIO)-ALKYLAMIDES
M. L. Taha, O. Moukha-Chafiq, H. B. Lazrek, J. J. Vasseur & J. L. Imbach
Pages: 955-958
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF SOME ACYCLONUCLEOSIDES α-(PYRAZOLO[3,4-d]PYRIMIDIN-4-YLTHIO)-ALKYLAMIDES | Full Text | References | PDF (89.3 KB)
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SYNTHESIS OF NEW HOMO AND HETERODINUCLEOSIDES CONTAINING THE 2′,3′-DIDEOXYNUCLEOSIDES AZT AND D4T
M. Taourirte, H. B. Lazrek, J. J. Vasseur, M. Ferrero, S. Fernandez & V. Gotor
Pages: 959-962
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF NEW HOMO AND HETERODINUCLEOSIDES CONTAINING THE 2′,3′-DIDEOXYNUCLEOSIDES AZT AND D4T | Full Text | References | PDF (83.1 KB)
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DIRECT MALDI-TOF MS ANALYSIS OF OLIGONUCLEOTIDES ON SOLID SUPPORT THROUGH A PHOTOLABILE LINKER
A. Meyer, N. Spinelli, J.-C. Brès, C. Dell'Aquila, F. Morvan, I. Lefebvre, B. Rayner, J.-L. Imbach & J.-J. Vasseur
Pages: 963-966
Published online: 07 Feb 2007
AbstractforDIRECT MALDI-TOF MS ANALYSIS OF OLIGONUCLEOTIDES ON SOLID SUPPORT THROUGH A PHOTOLABILE LINKER | Full Text | References | PDF (232.9 KB)
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5-(PHENYLTHIOMETHYL)-2′-DEOXYURIDINE AS AN EFFICIENT PHOTOREACTIVE PRECURSOR TO GENERATE SINGLE AND MULTIPLE LESIONS WITHIN DNA FRAGMENTS
Sophie Bellon, Didier Gasparutto, Anthony Romieu & Jean Cadet
Pages: 967-971
Published online: 07 Feb 2007
Abstractfor5-(PHENYLTHIOMETHYL)-2′-DEOXYURIDINE AS AN EFFICIENT PHOTOREACTIVE PRECURSOR TO GENERATE SINGLE AND MULTIPLE LESIONS WITHIN DNA FRAGMENTS | Full Text | References | PDF (135.6 KB)
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THE MOX/SUC PRECURSOR STRATEGIES: ROBUST WAYS TO CONSTRUCT FUNCTIONALIZED OLIGONUCLEOTIDES
N. Polushin
Pages: 973-976
Published online: 07 Feb 2007
AbstractforTHE MOX/SUC PRECURSOR STRATEGIES: ROBUST WAYS TO CONSTRUCT FUNCTIONALIZED OLIGONUCLEOTIDES | Full Text | References | PDF (85.6 KB)
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RECOMBINANT BACTERIAL CELLS AS EFFICIENT BIOCATALYSTS FOR THE PRODUCTION OF NUCLEOSIDES
E. Spoldi, D. Ghisotti, S. Calì, M. Grisa, G. Orsini, G. Tonon & G. Zuffi
Pages: 977-979
Published online: 07 Feb 2007
AbstractforRECOMBINANT BACTERIAL CELLS AS EFFICIENT BIOCATALYSTS FOR THE PRODUCTION OF NUCLEOSIDES | Full Text | References | PDF (70.5 KB)
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METHYL 5-O-BENZOYL-2,3-OXAZOLE-D-RIBOFURANOSIDE: A USEFUL INTERMEDIATE FOR THE SYNTHESIS OF CONFORMATIONALLY RESTRAINED NUCLEOSIDES
José Molina, Hannah L. Maslen & Claire Simons
Pages: 981-983
Published online: 07 Feb 2007
AbstractforMETHYL 5-O-BENZOYL-2,3-OXAZOLE-D-RIBOFURANOSIDE: A USEFUL INTERMEDIATE FOR THE SYNTHESIS OF CONFORMATIONALLY RESTRAINED NUCLEOSIDES | Full Text | References | PDF (73.6 KB)
  • 126 Views
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MULTIPLE OLIGONUCLEOTIDE SYNTHESIS IN TANDEM ON SOLID-PHASE SUPPORTS FOR SMALL AND LARGE SCALE SYNTHESIS
R. T. Pon, S. Yu & Y. S. Sanghvi
Pages: 985-989
Published online: 07 Feb 2007
AbstractforMULTIPLE OLIGONUCLEOTIDE SYNTHESIS IN TANDEM ON SOLID-PHASE SUPPORTS FOR SMALL AND LARGE SCALE SYNTHESIS | Full Text | References | PDF (88.1 KB)
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STUDIES OF A CHEMICALLY MODIFIED OLIGODEOXYNUCLEOTIDE CONTAINING A 5-ATOM AMIDE BACKBONE WHICH EXHIBITS IMPROVED BINDING TO RNA
Christopher J. Wilds, George Minasov, François Natt, Peter von Matt, Karl-Heinz Altmann & Martin Egli
Pages: 991-994
Published online: 07 Feb 2007
AbstractforSTUDIES OF A CHEMICALLY MODIFIED OLIGODEOXYNUCLEOTIDE CONTAINING A 5-ATOM AMIDE BACKBONE WHICH EXHIBITS IMPROVED BINDING TO RNA | Full Text | References | PDF (84.1 KB)
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Article
CHIMERIC RNA WITH MODIFIED BACKBONES: ALTERNATING METHYLENE(METHYLIMINO) LINKED PHOSPHODIESTER BACKBONE OLIGONUCLEOTIDES WITH 2′-OH AND 2′-OMe GROUPS
Marija Prhavc, Balkrishen Bhat, George Just, P. Dan Cook & Muthiah Manoharan
Pages: 995-997
Published online: 07 Feb 2007
AbstractforCHIMERIC RNA WITH MODIFIED BACKBONES: ALTERNATING METHYLENE(METHYLIMINO) LINKED PHOSPHODIESTER BACKBONE OLIGONUCLEOTIDES WITH 2′-OH AND 2′-OMe GROUPS | Full Text | References | PDF (103.8 KB)
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SYNTHESIS AND STRUCTURAL STUDY OF PYRIMIDYL CARBOCYCLIC ANALOGUES OF NUCLEOSIDES BASED ON CYCLOPENTENE RINGS
C. Terán, M. J. González Moa, R. Mosquera & L. Santana
Pages: 999-1002
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND STRUCTURAL STUDY OF PYRIMIDYL CARBOCYCLIC ANALOGUES OF NUCLEOSIDES BASED ON CYCLOPENTENE RINGS | Full Text | References | PDF (81.8 KB)
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SYNTHESIS OF 6-FORMYLURIDINE 5′-MONOPHOSPHATE: 6-FORMYL-UMP
Michael P. Groziak
Pages: 1003-1006
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF 6-FORMYLURIDINE 5′-MONOPHOSPHATE: 6-FORMYL-UMP | Full Text | References | PDF (103.9 KB)
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EFFICIENT SYNTHESIS OF OLIGONUCLEOTIDE-PEPTIDE CONJUGATES ON LARGE SCALE
Svetlana O. Doronina, Andrei P. Guzaev & Muthiah Manoharan
Pages: 1007-1010
Published online: 07 Feb 2007
AbstractforEFFICIENT SYNTHESIS OF OLIGONUCLEOTIDE-PEPTIDE CONJUGATES ON LARGE SCALE | Full Text | References | PDF (76.9 KB)
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Article
A NOVEL PROTECTING STRATEGY FOR INTERNUCLEOSIDIC PHOSPHATE AND PHOSPHOROTHIOATE GROUPS
Andrei P. Guzaev & Muthiah Manoharan
Pages: 1011-1014
Published online: 07 Feb 2007
AbstractforA NOVEL PROTECTING STRATEGY FOR INTERNUCLEOSIDIC PHOSPHATE AND PHOSPHOROTHIOATE GROUPS | Full Text | References | PDF (98.6 KB)
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Article
SYNTHESIS OF CHIMERIC OLIGONUCLEOTIDES CONTAINING INTERNUCLEOSIDIC PHOSPHODIESTER AND S–PIVALOYLTHIOETHYL PHOSPHOTRIESTER RESIDUES
Andrei P. Guzaev, Balkrishen Bhat, Guity Balow & Muthiah Manoharan
Pages: 1015-1018
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF CHIMERIC OLIGONUCLEOTIDES CONTAINING INTERNUCLEOSIDIC PHOSPHODIESTER AND S–PIVALOYLTHIOETHYL PHOSPHOTRIESTER RESIDUES | Full Text | References | PDF (96.1 KB)
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Article
SYNTHESIS AND PROPERTIES OF NOVEL TRIPHOSPHATE ANALOGUES: RIBONUCLEOSIDE AND DEOXYRIBONUCLEOSIDE (α-P-BORANO, α-P-THIO)TRIPHOSPHATES
Jinlai Lin, Kenneth W. Porter & Barbara Ramsay Shaw
Pages: 1019-1023
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND PROPERTIES OF NOVEL TRIPHOSPHATE ANALOGUES: RIBONUCLEOSIDE AND DEOXYRIBONUCLEOSIDE (α-P-BORANO, α-P-THIO)TRIPHOSPHATES | Full Text | References | PDF (96.6 KB)
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ANTIVIRAL ACTIVITY OF TENOFOVIR (PMPA) AGAINST NUCLEOSIDE-RESISTANT CLINICAL HIV SAMPLES
Michael D. Miller, Nicolas A. Margot, Kurt Hertogs, Brendan Larder & Veronica Miller
Pages: 1025-1028
Published online: 07 Feb 2007
AbstractforANTIVIRAL ACTIVITY OF TENOFOVIR (PMPA) AGAINST NUCLEOSIDE-RESISTANT CLINICAL HIV SAMPLES | Full Text | References | PDF (73.6 KB)
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SYNTHESIS AND ANTIVIRAL EVALUATION OF C-4-HYDRAZIDE DERIVATIVES OF 2′,3′-DIDEOXYCYTIDINE
Valérie Boudou-Vivet, Christophe Mathé & Gilles Gosselin
Pages: 1029-1032
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTIVIRAL EVALUATION OF C-4-HYDRAZIDE DERIVATIVES OF 2′,3′-DIDEOXYCYTIDINE | Full Text | References | PDF (79.5 KB)
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MODIFIED DINUCLEOSIDE TETRAPHOSPHONATES, NEW POTENTIAL INHIBITORS OF HIV REVERSE TRANSCRIPTASE
E. A. Shirokova, A. L. Khandazhinskaya, Yu. S. Skoblov, L. Ye. Goryunova, R. S. Beabealashvilli & A. A. Krayevsky
Pages: 1033-1036
Published online: 07 Feb 2007
AbstractforMODIFIED DINUCLEOSIDE TETRAPHOSPHONATES, NEW POTENTIAL INHIBITORS OF HIV REVERSE TRANSCRIPTASE | Full Text | References | PDF (81.2 KB)
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3′-DEOXYRIBOFURANOSE DERIVATIVES OF 1-DEAZA AND 3-DEAZA-ADENOSINE AND THEIR ACTIVITY AS ADENOSINE DEAMINASE INHIBITORS
S. Costanzi, C. Lambertucci, R. Volpini, S. Vittori, G. Lupidi & G. Cristalli
Pages: 1037-1041
Published online: 07 Feb 2007
Abstractfor3′-DEOXYRIBOFURANOSE DERIVATIVES OF 1-DEAZA AND 3-DEAZA-ADENOSINE AND THEIR ACTIVITY AS ADENOSINE DEAMINASE INHIBITORS | Full Text | References | PDF (94.8 KB)
  • 66 Views
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POTENT IN VITRO ANTICANCER ACTIVITIES OF RING-EXPANDED (“FAT”) NUCLEOSIDES CONTAINING THE IMIDAZO[4,5-E][1,3]DIAZEPINE RING SYSTEM
Juliana K. Gill, Lijuan Wang, Maria Bretner, Rachel Newman, Natasha Kyprianou & Ramachandra S. Hosmane
Pages: 1043-1045
Published online: 07 Feb 2007
AbstractforPOTENT IN VITRO ANTICANCER ACTIVITIES OF RING-EXPANDED (“FAT”) NUCLEOSIDES CONTAINING THE IMIDAZO[4,5-E][1,3]DIAZEPINE RING SYSTEM | Full Text | References | PDF (77.3 KB)
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N-PHENYLIMIDAZOLIUM TRIFLATE AS A HIGHLY EFFECTIVE PROMOTER FOR THE INTERRIBONUCLEOTIDE-BOND FORMATION VIA THE PHOSPHORAMIDITE METHOD
Rie Kawai, Jun-ichiro Sugimoto, Masanori Kataoka & Yoshihiro Hayakawa
Pages: 1047-1048
Published online: 07 Feb 2007
AbstractforN-PHENYLIMIDAZOLIUM TRIFLATE AS A HIGHLY EFFECTIVE PROMOTER FOR THE INTERRIBONUCLEOTIDE-BOND FORMATION VIA THE PHOSPHORAMIDITE METHOD | Full Text | References | PDF (69.2 KB)
  • 82 Views
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SYNTHESIS AND STUDY OF THE FLUORESCEIN CONJUGATE OF THE NUCLEOTIDE dPTP
W. J. Cummins, A. L. Hamilton, C. L. Smith & M. S. J. Briggs
Pages: 1049-1051
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND STUDY OF THE FLUORESCEIN CONJUGATE OF THE NUCLEOTIDE dPTP | Full Text | References | PDF (76.3 KB)
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SYNTHESIS AND IN VITRO ANTIVIRAL ACTIVITY EVALUATION OF 9-(2-AZIDO-2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)ADENINE DERIVATIVES
Satoshi Takamatsu, Kunisuke Izawa, Tokumi Maruyama, Satoshi Katayama, Naoko Hirose & Erik De Clercq
Pages: 1053-1057
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND IN VITRO ANTIVIRAL ACTIVITY EVALUATION OF 9-(2-AZIDO-2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)ADENINE DERIVATIVES | Full Text | References | PDF (93.2 KB)
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SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL EXOMETHYLENE CYCLOPROPYL NUCLEOSIDES
Bo Gil Choi, Eun Yee Kwak, Joon Hee Hong & Chong Kyo Lee
Pages: 1059-1062
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL EXOMETHYLENE CYCLOPROPYL NUCLEOSIDES | Full Text | References | PDF (85.6 KB)
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Article
BICYCLIC FURO PYRIMIDINE NUCLEOSIDES WITH ARYLOXYPHENYL AND HALOPHENYL SUBSTITUTED SIDE CHAINS AS POTENT AND SELECTIVE VARICELLA-ZOSTER VIRUS INHIBITORS
Sally Blewett, Christopher McGuigan, Hubert Barucki, Graciela Andrei, Robert Snoeck, Erik De Clercq & Jan Balzarini
Pages: 1063-1066
Published online: 07 Feb 2007
AbstractforBICYCLIC FURO PYRIMIDINE NUCLEOSIDES WITH ARYLOXYPHENYL AND HALOPHENYL SUBSTITUTED SIDE CHAINS AS POTENT AND SELECTIVE VARICELLA-ZOSTER VIRUS INHIBITORS | Full Text | References | PDF (87.6 KB)
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THE DESIGN AND SYNTHESIS OF PURINE INHIBITORS OF CDK2. III
P. W. Shum, N. P. Peet, P. M. Weintraub, T. B. Le, Z. Zhao, F. Barbone, B. Cashman, J. Tsay, S. Dwyer, P. C. Loos, E. A. Powers, K. Kropp, P. S. Wright, A. Bitonti, J. Dumont & D. R. Borcherding
Pages: 1067-1078
Published online: 07 Feb 2007
AbstractforTHE DESIGN AND SYNTHESIS OF PURINE INHIBITORS OF CDK2. III | Full Text | References | PDF (235.8 KB)
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Article
CHEMICAL CROSS-LINKING OF PEPTIDES DERIVED FROM RECA WITH SINGLE-STRANDED OLIGONUCLEOTIDES CONTAINING 5-FORMYL-2′-DEOXYURIDINE
Toru Sugiyama, Atsushi Kittaka, Hiroaki Takayama, Mitsugu Tomioka, Yoshiteru Ida & Reiko Kuroda
Pages: 1079-1083
Published online: 07 Feb 2007
AbstractforCHEMICAL CROSS-LINKING OF PEPTIDES DERIVED FROM RECA WITH SINGLE-STRANDED OLIGONUCLEOTIDES CONTAINING 5-FORMYL-2′-DEOXYURIDINE | Full Text | References | PDF (133.4 KB)
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PURIFICATION OF PMPA AMIDATE PRODRUGS BY SMB CHROMATOGRAPHY AND X-RAY CRYSTALLOGRAPHY OF THE DIASTEREOMERICALLY PURE GS-7340
H. Chapman, M. Kernan, J. Rohloff, M. Sparacino & T. Terhorst
Pages: 1085-1090
Published online: 07 Feb 2007
AbstractforPURIFICATION OF PMPA AMIDATE PRODRUGS BY SMB CHROMATOGRAPHY AND X-RAY CRYSTALLOGRAPHY OF THE DIASTEREOMERICALLY PURE GS-7340 | Full Text | References | PDF (92.4 KB)
  • 351 Views
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METABOLISM OF GS-7340, A NOVEL PHENYL MONOPHOSPHORAMIDATE INTRACELLULAR PRODRUG OF PMPA, IN BLOOD
Eugene J. Eisenberg, Gong-Xin He & William A. Lee
Pages: 1091-1098
Published online: 07 Feb 2007
AbstractforMETABOLISM OF GS-7340, A NOVEL PHENYL MONOPHOSPHORAMIDATE INTRACELLULAR PRODRUG OF PMPA, IN BLOOD | Full Text | References | PDF (249.7 KB)
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AN EFFICIENT PROCESS FOR THE SYNTHESIS OF CYCLIC HPMPC
Michael S. Louie & Harlan Chapman
Pages: 1099-1102
Published online: 07 Feb 2007
AbstractforAN EFFICIENT PROCESS FOR THE SYNTHESIS OF CYCLIC HPMPC | Full Text | References | PDF (80.1 KB)
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Article
SYNTHESIS OF 8-AMINO AND 8-SUBSTITUTED AMINO DERIVATIVES OF ACYCLIC PURINE NUCLEOSIDE AND NUCLEOTIDE ANALOGS. ALKYLATION OF 8-SUBSTITUTED PURINE BASES
Z. Janeba & A. Holý
Pages: 1103-1106
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF 8-AMINO AND 8-SUBSTITUTED AMINO DERIVATIVES OF ACYCLIC PURINE NUCLEOSIDE AND NUCLEOTIDE ANALOGS. ALKYLATION OF 8-SUBSTITUTED PURINE BASES | Full Text | References | PDF (92.3 KB)
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Article
MESSENGER RNA ISOLATION USING NOVEL PNA ANALOGUES
D. Phelan, K. Hondorp, M. Choob, V. Efimov & J. Fernandez
Pages: 1107-1111
Published online: 07 Feb 2007
AbstractforMESSENGER RNA ISOLATION USING NOVEL PNA ANALOGUES | Full Text | References | PDF (132.4 KB)
  • 90 Views
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SYNTHESIS OF MODIFIED NUCLEOSIDE 5′-TRIPHOSPHATES FOR IN VITRO SELECTION OF CATALYTIC NUCLEIC ACIDS
Jasenka Matulic-Adamic, Andrew T. Daniher, Alexander Karpeisky, Peter Haeberli, David Sweedler & Leonid Beigelman
Pages: 1113-1115
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF MODIFIED NUCLEOSIDE 5′-TRIPHOSPHATES FOR IN VITRO SELECTION OF CATALYTIC NUCLEIC ACIDS | Full Text | References | PDF (74.5 KB)
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LIN-BENZOARISTEROMYCIN
Vasanthakumar P. Rajappan & Stewart W. Schneller
Pages: 1117-1121
Published online: 07 Feb 2007
AbstractforLIN-BENZOARISTEROMYCIN | Full Text | References | PDF (88.4 KB)
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SYNTHESIS AND IN VITRO ACTIVITY OF D- AND L-ENANTIOMERS OF 5-(TRIFLUOROMETHYL)URACIL NUCLEOSIDE DERIVATIVES
Raul Salvetti, Massimo Pregnolato, Annalisa Verri, Federico Focher, Silvio Spadari, Arnaud Marchand, Christophe Mathé & Gilles Gosselin
Pages: 1123-1125
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND IN VITRO ACTIVITY OF D- AND L-ENANTIOMERS OF 5-(TRIFLUOROMETHYL)URACIL NUCLEOSIDE DERIVATIVES | Full Text | References | PDF (84.8 KB)
  • 110 Views
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NEW CARBOCYCLIC NUCLEOSIDES DERIVED FROM INDAN
F. Abad, F. Álvarez, F. Fernández, X. García-Mera & J. E. Rodríguez-Borges
Pages: 1127-1128
Published online: 07 Feb 2007
AbstractforNEW CARBOCYCLIC NUCLEOSIDES DERIVED FROM INDAN | Full Text | References | PDF (80.7 KB)
  • 57 Views
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MODIFIED CYCLOBUTANE CARBONUCLEOSIDES: SYNTHESIS AND EVALUATION OF THEIR ANTIVIRAL ACTIVITY
F. Fernández, A. R. Hergueta, C. López, E. De Clercq & J. Balzarini
Pages: 1129-1131
Published online: 07 Feb 2007
AbstractforMODIFIED CYCLOBUTANE CARBONUCLEOSIDES: SYNTHESIS AND EVALUATION OF THEIR ANTIVIRAL ACTIVITY | Full Text | References | PDF (93.2 KB)
  • 96 Views
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A CYCLOBUTANE CARBONUCLEOSIDE WITH MARKED SELECTIVITY AGAINST TK+ AND TK− VARICELLA ZOSTER VIRUS
C. López, C. Balo, J. M. Blanco, F. Fernández, E. De Clercq & J. Balzarini
Pages: 1133-1135
Published online: 07 Feb 2007
AbstractforA CYCLOBUTANE CARBONUCLEOSIDE WITH MARKED SELECTIVITY AGAINST TK+ AND TK− VARICELLA ZOSTER VIRUS | Full Text | References | PDF (80.6 KB)
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SYNTHESIS AND EVALUATION OF ANTIVIRAL ACTIVITY OF HIGHER HOMOLOGUES OF XYLO-CARBOCYCLIC NUCLEOSIDES
O. Caamaño, M. J. Figueira, F. Fernández, M. D. García, M. I. Nieto, E. de Clercq & J. Balzarini
Pages: 1137-1139
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND EVALUATION OF ANTIVIRAL ACTIVITY OF HIGHER HOMOLOGUES OF XYLO-CARBOCYCLIC NUCLEOSIDES | Full Text | References | PDF (73.5 KB)
  • 25 Views
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NOVEL NUCLEOSIDE TRIPHOSPHATE ANALOGS FOR THE ENZYMATIC LABELING OF NUCLEIC ACIDS
A. D. Barone, C. Chen, G. H. McGall, K. Rafii, Philip R. Buzby & James J. Dimeo
Pages: 1141-1145
Published online: 07 Feb 2007
AbstractforNOVEL NUCLEOSIDE TRIPHOSPHATE ANALOGS FOR THE ENZYMATIC LABELING OF NUCLEIC ACIDS | Full Text | References | PDF (85.6 KB)
  • 73 Views
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6-AZACYTIDINE - COMPOUND WITH WIDE SPECTRUM OF ANTIVIRAL ACTIVITY
I. Alexeeva, N. Dyachenko, L. Nosach, V. Zhovnovataya, S. Rybalko, R. Lozitskaya, A. Fedchuk, V. Lozitsky, T. Gridina, A. Shalamay, L. Palchikovskaja & O. Povnitsa
Pages: 1147-1152
Published online: 07 Feb 2007
Abstractfor6-AZACYTIDINE - COMPOUND WITH WIDE SPECTRUM OF ANTIVIRAL ACTIVITY | Full Text | References | PDF (254.6 KB)
  • 86 Views
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SYNTHESIS AND ADENOSINE RECEPTOR AFFINITY AND POTENCY OF 8-ALKYNYL DERIVATIVES OF ADENOSINE
C. Lambertucci, S. Costanzi, S. Vittori, R. Volpini & G. Cristalli
Pages: 1153-1157
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND ADENOSINE RECEPTOR AFFINITY AND POTENCY OF 8-ALKYNYL DERIVATIVES OF ADENOSINE | Full Text | References | PDF (90.2 KB)
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KINETICS STUDY OF THE BIOTRANSFORMATION OF AN OLIGONUCLEOTIDE PRODRUG IN CELLS EXTRACT BY MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY
François Morvan, Jean-Charles Brès, Isabelle Lefebvre, Jean-Jacques Vasseur, Alain Pompon & Jean-Louis Imbach
Pages: 1159-1163
Published online: 07 Feb 2007
AbstractforKINETICS STUDY OF THE BIOTRANSFORMATION OF AN OLIGONUCLEOTIDE PRODRUG IN CELLS EXTRACT BY MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY | Full Text | References | PDF (92.3 KB)
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Article
CELLULAR UPTAKE AND INTRACELLULAR QUANTIFICATION OF FLUORESCENT LABELED T20 ME-SATE PROOLIGONUCLEOTIDES
François Morvan, J. C. Bologna, E. Vivès & Jean-Louis Imbach
Pages: 1165-1168
Published online: 07 Feb 2007
AbstractforCELLULAR UPTAKE AND INTRACELLULAR QUANTIFICATION OF FLUORESCENT LABELED T20 ME-SATE PROOLIGONUCLEOTIDES | Full Text | References | PDF (132.2 KB)
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KINETICALLY SELECTIVE BINDING OF SINGLE STRANDED RNA OVER DNA BY A PYRROLIDINE-AMIDE OLIGONUCLEOTIDE MIMIC (POM)
David T. Hickman, Paul M. King, Jonathan M. Slater, Matthew A. Cooper & Jason Micklefield
Pages: 1169-1172
Published online: 07 Feb 2007
AbstractforKINETICALLY SELECTIVE BINDING OF SINGLE STRANDED RNA OVER DNA BY A PYRROLIDINE-AMIDE OLIGONUCLEOTIDE MIMIC (POM) | Full Text | References | PDF (90.9 KB)
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SYNTHESIS AND BIOPHYSICAL STUDIES OF OLIGONUCLEOTIDES CONTAINING HYDROXAMATE LINKAGES
Kanda S. Ramasamy, Vesna Stoisavljevic & Johnson Y. N. Lau
Pages: 1173-1176
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BIOPHYSICAL STUDIES OF OLIGONUCLEOTIDES CONTAINING HYDROXAMATE LINKAGES | Full Text | References | PDF (84.4 KB)
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LABELING DURING CLEAVAGE (LDC), A NEW LABELING APPROACH FOR RNA
V. Monnot, C. Tora, S. Lopez, L. Menou & A. Laayoun
Pages: 1177-1179
Published online: 07 Feb 2007
AbstractforLABELING DURING CLEAVAGE (LDC), A NEW LABELING APPROACH FOR RNA | Full Text | References | PDF (73.1 KB)
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Article
NEW APPROACHES TOWARDS FLUORESCENCE LABELLING OF MESSENGER RNA TRANSCRIPTS
Arlette Garnier, Dieter Hüsken & Jan Weiler
Pages: 1181-1185
Published online: 07 Feb 2007
AbstractforNEW APPROACHES TOWARDS FLUORESCENCE LABELLING OF MESSENGER RNA TRANSCRIPTS | Full Text | References | PDF (210.8 KB)
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ENGINEERING PREFERENCES OF HAIRPIN PNA BINDING TO COMPLEMENTARY DNA: EFFECT OF N7G IN aeg/aep PNA BACKBONE
V. A. Kumar, M. D'Costa & K. N. Ganesh
Pages: 1187-1191
Published online: 07 Feb 2007
AbstractforENGINEERING PREFERENCES OF HAIRPIN PNA BINDING TO COMPLEMENTARY DNA: EFFECT OF N7G IN aeg/aep PNA BACKBONE | Full Text | References | PDF (94.2 KB)
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SYNTHESIS AND EVALUATION OF PROLYL CARBAMATE NUCLEIC ACIDS (PrCNA)
Meena, V. A. Kumar & K. N. Ganesh
Pages: 1193-1196
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND EVALUATION OF PROLYL CARBAMATE NUCLEIC ACIDS (PrCNA) | Full Text | References | PDF (86 KB)
  • 45 Views
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CONSTRAINED FLEXIBILITY IN PNA: DNA BINDING STUDIES WITH BRIDGED AMINOPROPYLGLYCYL PNA
P. S. Lonkar, V. A. Kumar & K. N. Ganesh
Pages: 1197-1200
Published online: 07 Feb 2007
AbstractforCONSTRAINED FLEXIBILITY IN PNA: DNA BINDING STUDIES WITH BRIDGED AMINOPROPYLGLYCYL PNA | Full Text | References | PDF (82.6 KB)
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EXTRA STABLE 2′,5′-LINKED RNA LOOPS
Rami N. Hannoush & Masad J. Damha
Pages: 1201-1204
Published online: 07 Feb 2007
AbstractforEXTRA STABLE 2′,5′-LINKED RNA LOOPS | Full Text | References | PDF (81.4 KB)
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Article
EFFECT OF SUBSTITUTING ARABINONUCLEOSIDES FOR DEOXYNUCLEOTIDES IN THE DNA PRIMING STRAND ON THE POLYMERASE ACTION OF HIV-1 RT
Anne M. Noronha, Dominique Arion, Michael A. Parniak & Masad J. Damha
Pages: 1205-1209
Published online: 07 Feb 2007
AbstractforEFFECT OF SUBSTITUTING ARABINONUCLEOSIDES FOR DEOXYNUCLEOTIDES IN THE DNA PRIMING STRAND ON THE POLYMERASE ACTION OF HIV-1 RT | Full Text | References | PDF (86.2 KB)
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MOLECULAR MODELLING OF 2′-OH MEDIATED HYDROGEN BONDING IN RIBONUCLEOS(T)IDES BY NMR CONSTRAINED AM1 AND MMX CALCULATIONS
Parag Acharya, Irina Velikian, Sandipta Acharya & Jyoti Chattopadhyaya
Pages: 1211-1217
Published online: 07 Feb 2007
AbstractforMOLECULAR MODELLING OF 2′-OH MEDIATED HYDROGEN BONDING IN RIBONUCLEOS(T)IDES BY NMR CONSTRAINED AM1 AND MMX CALCULATIONS | Full Text | References | PDF (126.5 KB)
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DO THE 16 MER, 5′-GUGGUCUGAUGAGGCC-3′ AND THE 25 MER, 5′-GGCCGAAACUCGUAAGAGUCACCAC-3′, FORM A HAMMERHEAD RIBOZYME STRUCTURE IN PHYSIOLOGICAL CONDITIONS? AN NMR AND UV THERMODYNAMIC STUDY
Edouard Zamaratski, Anna Trifonova, Parag Acharya, Johan Isaksson, Tatiana Maltseva & Jyoti Chattopadhayaya
Pages: 1219-1223
Published online: 07 Feb 2007
AbstractforDO THE 16 MER, 5′-GUGGUCUGAUGAGGCC-3′ AND THE 25 MER, 5′-GGCCGAAACUCGUAAGAGUCACCAC-3′, FORM A HAMMERHEAD RIBOZYME STRUCTURE IN PHYSIOLOGICAL CONDITIONS? AN NMR AND UV THERMODYNAMIC STUDY | Full Text | References | PDF (118.5 KB)
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Article
THE NMR CONFORMATION STUDY OF THE COMPLEXES OF DEOXYCYTIDINE KINASE (dCK) AND 2′-DEOXYCYTIDINE/2′-DEOXYADENOSINE
T. Maltseva, E. Usova, S. Eriksson, J. Milecki, A. Földesi & J. Chattopadhayaya
Pages: 1225-1228
Published online: 07 Feb 2007
AbstractforTHE NMR CONFORMATION STUDY OF THE COMPLEXES OF DEOXYCYTIDINE KINASE (dCK) AND 2′-DEOXYCYTIDINE/2′-DEOXYADENOSINE | Full Text | References | PDF (75.2 KB)
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Article
AN ENERGETIC CORRELATION OF AB INITIO AND NMR STUDIES OF THE 3′-GAUCHE EFFECT IN 3′-SUBSTITUTED THYMIDINES
Parag Acharya, Christophe Thibaudeau & Jyoti Chattopadhyaya
Pages: 1229-1233
Published online: 07 Feb 2007
AbstractforAN ENERGETIC CORRELATION OF AB INITIO AND NMR STUDIES OF THE 3′-GAUCHE EFFECT IN 3′-SUBSTITUTED THYMIDINES | Full Text | References | PDF (177.6 KB)
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PROMOTION OF TRIPLEX FORMATION BY 2′-O,4′-C-METHYLENE BRIDGED NUCLEIC ACID (2′,4′-BNA) MODIFICATION: THERMODYNAMIC AND KINETIC STUDIES
Hidetaka Torigoe, Satoshi Obika & Takeshi Imanishi
Pages: 1235-1238
Published online: 07 Feb 2007
AbstractforPROMOTION OF TRIPLEX FORMATION BY 2′-O,4′-C-METHYLENE BRIDGED NUCLEIC ACID (2′,4′-BNA) MODIFICATION: THERMODYNAMIC AND KINETIC STUDIES | Full Text | References | PDF (80.1 KB)
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A DNA-BINDING PEPTIDE FROM A PHAGE DISPLAY LIBRARY
Julian Wölcke & Elmar Weinhold
Pages: 1239-1241
Published online: 07 Feb 2007
AbstractforA DNA-BINDING PEPTIDE FROM A PHAGE DISPLAY LIBRARY | Full Text | References | PDF (105.5 KB)
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Article
INHIBITION OF HUMAN TELOMERASE BY L-ENANTIOMERS OF NATURAL 2′-DEOXYRIBONUCLEOSIDE 5′-TRIPHOSPHATES
Toyofumi Yamaguchi, Rieko Yamada, Aki Tomikawa, Koichi Shudo, Motoki Saito, Fuyuki Ishikawa & Mineo Saneyoshi
Pages: 1243-1246
Published online: 07 Feb 2007
AbstractforINHIBITION OF HUMAN TELOMERASE BY L-ENANTIOMERS OF NATURAL 2′-DEOXYRIBONUCLEOSIDE 5′-TRIPHOSPHATES | Full Text | References | PDF (132.1 KB)
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MECHANISTIC STUDIES TO UNDERSTAND THE INHIBITION OF WILD TYPE AND MUTANT HIV-1 REVERSE TRANSCRIPTASE BY CARBOVIR-TRIPHOSPHATE
Adrian S. Ray & Karen S. Anderson
Pages: 1247-1250
Published online: 07 Feb 2007
AbstractforMECHANISTIC STUDIES TO UNDERSTAND THE INHIBITION OF WILD TYPE AND MUTANT HIV-1 REVERSE TRANSCRIPTASE BY CARBOVIR-TRIPHOSPHATE | Full Text | References | PDF (74.8 KB)
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ACCELERATION OF NUCLEIC ACID HYBRIDIZATION ON DNA MICROARRAYS DRIVEN BY pH TUNABLE MODIFICATIONS
Peiming Zhang, Natalia Briones, Chang-Gong Liu, Charles K. Brush, Tom Powdrill, Yuri Belosludtsev & Mike Hogan
Pages: 1251-1254
Published online: 07 Feb 2007
AbstractforACCELERATION OF NUCLEIC ACID HYBRIDIZATION ON DNA MICROARRAYS DRIVEN BY pH TUNABLE MODIFICATIONS | Full Text | References | PDF (147.6 KB)
  • 69 Views
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LABORATORY DIAGNOSIS OF RESPIRATORY DISEASES: PCR VERSUS SEROLOGY
H. Haaheim, L. Vorland & T. J. Gutteberg
Pages: 1255-1258
Published online: 07 Feb 2007
AbstractforLABORATORY DIAGNOSIS OF RESPIRATORY DISEASES: PCR VERSUS SEROLOGY | Full Text | References | PDF (73.3 KB)
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PHOTOSENSITIZED AND CATALYTIC OXIDATION OF DNA BY METALLOPHTHALOCYANINE-OLIGONUCLEOTIDE CONJUGATES
V. V. Koval, A. A. Chernonosov, T. V. Abramova, T. M. Ivanova, O. S. Fedorova, V. M. Derkacheva & E. A. Lukyanets
Pages: 1259-1262
Published online: 07 Feb 2007
AbstractforPHOTOSENSITIZED AND CATALYTIC OXIDATION OF DNA BY METALLOPHTHALOCYANINE-OLIGONUCLEOTIDE CONJUGATES | Full Text | References | PDF (87.3 KB)
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SYNTHESIS OF 2′,3′-DIDEOXY-2′,3′-DIDEHYDRO NUCLEOSIDES VIA A SERENDIPITOUS ROUTE
Z. Guo, Y. S. Sanghvi, L. E. Brammer Jr. & T. Hudlicky
Pages: 1263-1266
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF 2′,3′-DIDEOXY-2′,3′-DIDEHYDRO NUCLEOSIDES VIA A SERENDIPITOUS ROUTE | Full Text | References | PDF (85.2 KB)
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UNEXPECTED RESULTS AND RECOURSE IN PROCESS OPTIMIZATION OF NUCLEOSIDE 3′-O-SUCCINATES
Quanlai Song & Yogesh S. Sanghvi
Pages: 1267-1270
Published online: 07 Feb 2007
AbstractforUNEXPECTED RESULTS AND RECOURSE IN PROCESS OPTIMIZATION OF NUCLEOSIDE 3′-O-SUCCINATES | Full Text | References | PDF (85.9 KB)
  • 145 Views
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A NEW FACILE METHOD FOR SPIN-LABELING OF OLIGONUCLEOTIDES
Thorsten Strube, Olav Schiemann, Fraser MacMillan, Thomas Prisner & Joachim W. Engels
Pages: 1271-1274
Published online: 07 Feb 2007
AbstractforA NEW FACILE METHOD FOR SPIN-LABELING OF OLIGONUCLEOTIDES | Full Text | References | PDF (78.4 KB)
  • 59 Views
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Article
PHENYLALKYL BACKBONE MODIFIED OLIGODEOXYNUCLEOTIDES, THEIR SYNTHESIS AND THE INFLUENCE OF THE ALKYL CHAIN LENGTH
Stefan Amberg & Joachim W. Engels
Pages: 1275-1278
Published online: 07 Feb 2007
AbstractforPHENYLALKYL BACKBONE MODIFIED OLIGODEOXYNUCLEOTIDES, THEIR SYNTHESIS AND THE INFLUENCE OF THE ALKYL CHAIN LENGTH | Full Text | References | PDF (78.9 KB)
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SYNTHESIS AND BASE PAIRING PROPERTIES OF 9-DEAZAPURINE N7-NUCLEOSIDES IN OLIGONUCLEOTIDE DUPLEXES AND TRIPLEXES
P. Leonard, T. Wiglenda & F. Seela
Pages: 1279-1282
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BASE PAIRING PROPERTIES OF 9-DEAZAPURINE N7-NUCLEOSIDES IN OLIGONUCLEOTIDE DUPLEXES AND TRIPLEXES | Full Text | References | PDF (94.4 KB)
  • 60 Views
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Article
PARALLEL DNA CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE ANALOGUES OF ISOGUANINE
F. Seela, R. Kröschel & Y. He
Pages: 1283-1286
Published online: 07 Feb 2007
AbstractforPARALLEL DNA CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE ANALOGUES OF ISOGUANINE | Full Text | References | PDF (88 KB)
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BRIDGED CYCLIC OLIGORIBONUCLEOTIDES—TOWARDS MODELS FOR CODON-ANTICODON PAIRING
R. Micura, W. Pils, K. Grubmayr, M.-O. Ebert & B. Jaun
Pages: 1287-1289
Published online: 07 Feb 2007
AbstractforBRIDGED CYCLIC OLIGORIBONUCLEOTIDES—TOWARDS MODELS FOR CODON-ANTICODON PAIRING | Full Text | References | PDF (143.7 KB)
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LARGE-SCALE MANUFACTURING OF ALL FOUR 2′-DEOXYNUCLEOSIDES VIA NOVEL STRATEGIES INCLUDING A CHEMO-ENZYMATIC PROCESS
Hironori Komatsu, Hirokazu Awano, Hiroharu Tanikawa, Kiyoshi Itou & Ichirou Ikeda
Pages: 1291-1293
Published online: 07 Feb 2007
AbstractforLARGE-SCALE MANUFACTURING OF ALL FOUR 2′-DEOXYNUCLEOSIDES VIA NOVEL STRATEGIES INCLUDING A CHEMO-ENZYMATIC PROCESS | Full Text | References | PDF (73.5 KB)
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KINETIC STUDIES OF THE DEGRADATION OF OXYCARBONYLOXYMETHYL PRODRUG OF ADEFOVIR AND TENOFOVIR IN SOLUTION
Reza Oliyai, Lung-Chi Yuan & Terry Dahl
Pages: 1295-1298
Published online: 07 Feb 2007
AbstractforKINETIC STUDIES OF THE DEGRADATION OF OXYCARBONYLOXYMETHYL PRODRUG OF ADEFOVIR AND TENOFOVIR IN SOLUTION | Full Text | References | PDF (72.3 KB)
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DEALKYLATION OF PHOSPHONATE ESTERS WITH CHLOROTRIMETHYLSILANE
A. J. Gutierrez, E. J. Prisbe & J. C. Rohloff
Pages: 1299-1302
Published online: 07 Feb 2007
AbstractforDEALKYLATION OF PHOSPHONATE ESTERS WITH CHLOROTRIMETHYLSILANE | Full Text | References | PDF (83.4 KB)
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SYNTHESES OF DNA DUPLEXES CONTAINING A C‒C INTERSTRAND CROSS-LINK
Anne M. Noronha, David M. Noll & Paul S. Miller
Pages: 1303-1307
Published online: 07 Feb 2007
AbstractforSYNTHESES OF DNA DUPLEXES CONTAINING A C‒C INTERSTRAND CROSS-LINK | Full Text | References | PDF (86.8 KB)
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SYNTHESIS AND NMR-ANALYSIS OF TRICYCLIC NUCLEOSIDES
Poul Nielsen, Michael Petersen & Jens Peter Jacobsen
Pages: 1309-1312
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND NMR-ANALYSIS OF TRICYCLIC NUCLEOSIDES | Full Text | References | PDF (103.4 KB)
  • 57 Views
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SPECIFIC BINDING AND STABILIZATION OF DNA AND PHOSPHOROTHIOATE DNA BY AMPHIPHILIC α-HELICAL PEPTIDES
Takanori Kubo & Masayuki Fujii
Pages: 1313-1316
Published online: 07 Feb 2007
AbstractforSPECIFIC BINDING AND STABILIZATION OF DNA AND PHOSPHOROTHIOATE DNA BY AMPHIPHILIC α-HELICAL PEPTIDES | Full Text | References | PDF (83.6 KB)
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AMPHIPHILIC β-SHEET PEPTIDES CAN BIND TO DOUBLE AND TRIPLE STRANDED DNA
Kinuko Yokoyama, Takanori Kubo & Masayuki Fujii
Pages: 1317-1320
Published online: 07 Feb 2007
AbstractforAMPHIPHILIC β-SHEET PEPTIDES CAN BIND TO DOUBLE AND TRIPLE STRANDED DNA | Full Text | References | PDF (75.6 KB)
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A NOVEL APPROACH FOR THE SOLID PHASE SYNTHESIS OF DNA-PEPTIDE CONJUGATES
Takanori Kubo, Krishna Dubey & Masayuki Fujii
Pages: 1321-1324
Published online: 07 Feb 2007
AbstractforA NOVEL APPROACH FOR THE SOLID PHASE SYNTHESIS OF DNA-PEPTIDE CONJUGATES | Full Text | References | PDF (102 KB)
  • 84 Views
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SYNTHESIS OF A NOVEL NUCLEIC ACID MIMIC: P-BORANOMETHYLPHOSPHONATE
Jinlai Lin & Barbara Ramsay Shaw
Pages: 1325-1328
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF A NOVEL NUCLEIC ACID MIMIC: P-BORANOMETHYLPHOSPHONATE | Full Text | References | PDF (83.8 KB)
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A NEW SYNTHETIC METHODOLOGY FOR TIAZOFURIN
Kanda S. Ramasamy & Johnson Y. N. Lau
Pages: 1329-1331
Published online: 07 Feb 2007
AbstractforA NEW SYNTHETIC METHODOLOGY FOR TIAZOFURIN | Full Text | References | PDF (78.5 KB)
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SYNTHETIC STUDIES TO IMPROVE THE DEUTERIUM LABELLING IN NUCLEOSIDES FOR FACILITATING STRUCTURAL STUDIES OF LARGE RNAS BY HIGH-FIELD NMR SPECTROSCOPY
Mrinal K. Kundu, Anna Trifonova, Zoltán Dinya, András Földesi & Jyoti Chattopadhyaya
Pages: 1333-1337
Published online: 07 Feb 2007
AbstractforSYNTHETIC STUDIES TO IMPROVE THE DEUTERIUM LABELLING IN NUCLEOSIDES FOR FACILITATING STRUCTURAL STUDIES OF LARGE RNAS BY HIGH-FIELD NMR SPECTROSCOPY | Full Text | References | PDF (108 KB)
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THE SYNTHESIS OF, AND STUDIES ON, 2′-C-MODIFIED NUCLEOTIDES
Lavinia Brennan, Kevin J. Fettes, Ian A. O'Neil & Richard Cosstick
Pages: 1339-1341
Published online: 07 Feb 2007
AbstractforTHE SYNTHESIS OF, AND STUDIES ON, 2′-C-MODIFIED NUCLEOTIDES | Full Text | References | PDF (71.2 KB)
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DESIGN AND PROPERTIES OF HEPATITIS C VIRUS ANTISENSE OLIGONUCLEOTIDES FOR LIVER SPECIFIC DRUG TARGETING
Thomas J. Lehmann, Matthias Serwe, Wolfgang H. Caselmann & Joachim W. Engels
Pages: 1343-1346
Published online: 07 Feb 2007
AbstractforDESIGN AND PROPERTIES OF HEPATITIS C VIRUS ANTISENSE OLIGONUCLEOTIDES FOR LIVER SPECIFIC DRUG TARGETING | Full Text | References | PDF (102.6 KB)
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NOVEL MACROCYCLES DERIVED FROM NUCLEOSIDES
Noelia Calcerrada-Muñoz, Ian O'Neil & Richard Cosstick
Pages: 1347-1350
Published online: 07 Feb 2007
AbstractforNOVEL MACROCYCLES DERIVED FROM NUCLEOSIDES | Full Text | References | PDF (82.7 KB)
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SOLID-PHASE SYNTHESIS OF OLIGODEOXYNUCLEOTIDES CONTAINING 3′-S-PHOSPHOROTHIOLATE LINKAGES
Kevin J. Fettes, Ian O'Neil, Stanley M. Roberts & Richard Cosstick
Pages: 1351-1354
Published online: 07 Feb 2007
AbstractforSOLID-PHASE SYNTHESIS OF OLIGODEOXYNUCLEOTIDES CONTAINING 3′-S-PHOSPHOROTHIOLATE LINKAGES | Full Text | References | PDF (80.7 KB)
  • 88 Views
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SYNTHESIS AND BIOLOGICAL ACTIVITIES OF CYCLIC ADP-CARBOCYCLIC-RIBOSE AND ITS ANALOGS
Masayoshi Fukuoka, Satoshi Shuto, Noriaki Minakawa, Yoshihito Ueno & Akira Matsuda
Pages: 1355-1358
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND BIOLOGICAL ACTIVITIES OF CYCLIC ADP-CARBOCYCLIC-RIBOSE AND ITS ANALOGS | Full Text | References | PDF (88 KB)
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RESOLUTION OF RACEMIC MIXTURES OF CARBOCYCLIC ANALOGUES OF NUCLEOSIDES AND ASSIGNMENT OF THEIR ABSOLUTE CONFIGURATION
P. Besada, C. Terán, E. Quezada, J. M. Seco & E. Uriarte
Pages: 1359-1361
Published online: 07 Feb 2007
AbstractforRESOLUTION OF RACEMIC MIXTURES OF CARBOCYCLIC ANALOGUES OF NUCLEOSIDES AND ASSIGNMENT OF THEIR ABSOLUTE CONFIGURATION | Full Text | References | PDF (76.3 KB)
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1,2-DISUBSTITUTED CYCLOHEXANE CARBOCYCLIC ANALOGUES OF NUCLEOSIDES
D. Viña, L. Santana & E. Uriarte
Pages: 1363-1365
Published online: 07 Feb 2007
Abstractfor1,2-DISUBSTITUTED CYCLOHEXANE CARBOCYCLIC ANALOGUES OF NUCLEOSIDES | Full Text | References | PDF (75.2 KB)
  • 59 Views
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ASYMMETRIC SYNTHESIS OF CARBOCYCLIC PYRIMIDINE NUCLEOSIDES VIA π-ALLYLPALLADIUM COMPLEX
Junxing Shi & Raymond F. Schinazi
Pages: 1367-1370
Published online: 07 Feb 2007
AbstractforASYMMETRIC SYNTHESIS OF CARBOCYCLIC PYRIMIDINE NUCLEOSIDES VIA π-ALLYLPALLADIUM COMPLEX | Full Text | References | PDF (89.9 KB)
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THE USE AND EVALUATION OF 2+2 PHOTOADDITION IN IMMOBILIZATION OF OLIGONUCLEOTIDES ON A THREE DIMENSIONAL HYDROGEL MATRIX
R. Elghanian, Y. Xu, J. McGowen, M. Seithoff, C. G. Liu, J. Winick, N. Fuller, R. Ramakrishnan, A. Beuhler, T. Johnson, A. Mazumder & C. K. Brush
Pages: 1371-1375
Published online: 07 Feb 2007
AbstractforTHE USE AND EVALUATION OF 2+2 PHOTOADDITION IN IMMOBILIZATION OF OLIGONUCLEOTIDES ON A THREE DIMENSIONAL HYDROGEL MATRIX | Full Text | References | PDF (156.2 KB)
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SYNTHESIS AND HYBRIDIZATION OF NOVEL CHIRAL PYRROLIDINE BASED PNA ANALOGUE
Andis Slaitas & Esther Yeheskiely
Pages: 1377-1379
Published online: 07 Feb 2007
AbstractforSYNTHESIS AND HYBRIDIZATION OF NOVEL CHIRAL PYRROLIDINE BASED PNA ANALOGUE | Full Text | References | PDF (79.5 KB)
  • 59 Views
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EVALUATION OF SEVERAL ECONOMICAL COMPUTATIONAL METHODS FOR GEOMETRY OPTIMISATION OF PHOSPHORUS ACID DERIVATIVES
Susannah Sigurdsson & Roger Strömberg
Pages: 1381-1384
Published online: 07 Feb 2007
AbstractforEVALUATION OF SEVERAL ECONOMICAL COMPUTATIONAL METHODS FOR GEOMETRY OPTIMISATION OF PHOSPHORUS ACID DERIVATIVES | Full Text | References | PDF (74 KB)
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A METHOD FOR SYNTHESIS OF AN ARTIFICIAL RIBONUCLEASE
Hans Åström & Roger Strömberg
Pages: 1385-1388
Published online: 07 Feb 2007
AbstractforA METHOD FOR SYNTHESIS OF AN ARTIFICIAL RIBONUCLEASE | Full Text | References | PDF (92.5 KB)
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PREPARATION OF 3′-C-BRANCHED URIDINE ANALOGUES, SUITABLE FOR CONVERSION INTO FUNCTIONALISED 3′-C-METHYLENE DERIVATIVES
Anna Winqvist & Roger Strömberg
Pages: 1389-1392
Published online: 07 Feb 2007
AbstractforPREPARATION OF 3′-C-BRANCHED URIDINE ANALOGUES, SUITABLE FOR CONVERSION INTO FUNCTIONALISED 3′-C-METHYLENE DERIVATIVES | Full Text | References | PDF (87.2 KB)
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SYNTHESIS OF NEW CHIRAL PEPTIDE NUCLEIC ACID (PNA) MONOMERS
Bogdan Falkiewicz, Wojciech Wiśniowski, Aleksandra S. Kołodziejczyk & Kazimierz Wiśniewski
Pages: 1393-1397
Published online: 07 Feb 2007
AbstractforSYNTHESIS OF NEW CHIRAL PEPTIDE NUCLEIC ACID (PNA) MONOMERS | Full Text | References | PDF (96.6 KB)
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RESTRICTED ROTATION IN CHIRAL PEPTIDE NUCLEIC ACID (PNA) MONOMERS - INFLUENCE OF SUBSTITUENTS STUDIED BY MEANS OF 1H NMR
Marta Oleszczuk, Sylwia Rodziewicz-Motowidło & Bogdan Falkiewicz
Pages: 1399-1402
Published online: 07 Feb 2007
AbstractforRESTRICTED ROTATION IN CHIRAL PEPTIDE NUCLEIC ACID (PNA) MONOMERS - INFLUENCE OF SUBSTITUENTS STUDIED BY MEANS OF 1H NMR | Full Text | References | PDF (81.3 KB)
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PREPARATION OF OLIGODEOXYNUCLEOTIDE 5′-TRIPHOSPHATES USING SOLID SUPPORT APPROACH
A. V. Lebedev, I. I. Koukhareva, T. Beck & M. M. Vaghefi
Pages: 1403-1409
Published online: 07 Feb 2007
AbstractforPREPARATION OF OLIGODEOXYNUCLEOTIDE 5′-TRIPHOSPHATES USING SOLID SUPPORT APPROACH | Full Text | References | PDF (172.9 KB)
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PHARMACOKINETICS OF SALICYLATE ESTER PRODRUGS OF CYCLIC HPMPC IN DOGS
Reza Oliyai, Murty N. Arimilli, Robert J. Jones & William A. Lee
Pages: 1411-1414
Published online: 07 Feb 2007
AbstractforPHARMACOKINETICS OF SALICYLATE ESTER PRODRUGS OF CYCLIC HPMPC IN DOGS | Full Text | References | PDF (101.3 KB)
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LC/MS DETERMINATION OF THE INTRACELLULAR CONCENTRATION OF TWO NOVEL ARYL PHOSPHORAMIDATE PRODRUGS OF PMPA AND THEIR METABOLITES IN DOG PBMC
Theresa Lynch, Gene Eisenberg & Michael Kernan
Pages: 1415-1419
Published online: 07 Feb 2007
AbstractforLC/MS DETERMINATION OF THE INTRACELLULAR CONCENTRATION OF TWO NOVEL ARYL PHOSPHORAMIDATE PRODRUGS OF PMPA AND THEIR METABOLITES IN DOG PBMC | Full Text | References | PDF (85.7 KB)
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PHOSPHORAMIDITES AND OLIGONUCLEOTIDES CONTAINING 7-DEAZAPURINES AND PYRIMIDINES CARRYING AMINOPROPARGYL SIDE CHAINS
F. Seela, N. Ramzaeva, P. Leonard, Y. Chen, H. Debelak, E. Feiling, R. Kröschel, M. Zulauf, T. Wenzel, T. Fröhlich & M. Kostrzewa
Pages: 1421-1424
Published online: 07 Feb 2007
AbstractforPHOSPHORAMIDITES AND OLIGONUCLEOTIDES CONTAINING 7-DEAZAPURINES AND PYRIMIDINES CARRYING AMINOPROPARGYL SIDE CHAINS | Full Text | References | PDF (96.6 KB)
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ANTISENSE OLIGONUCLEOTIDE ISIS 2922 TARGETS IE-EXPRESSION AND PREVENTS HCMV-IE-INDUCED SUPPRESSION OF TSP-1 AND TSP-2 EXPRESSION
S. Margraf, M. Bittoova, J-U. Vogel, R. Kotchekov, H. W. Doerr & J. Cinatl Jr.
Pages: 1425-1428
Published online: 07 Feb 2007
AbstractforANTISENSE OLIGONUCLEOTIDE ISIS 2922 TARGETS IE-EXPRESSION AND PREVENTS HCMV-IE-INDUCED SUPPRESSION OF TSP-1 AND TSP-2 EXPRESSION | Full Text | References | PDF (117.8 KB)
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BASE MUTATION ANALYSIS BY A FERROCENYL NAPHTHALENE DIIMIDE DERIVATIVE
Shigeori Takenaka, Hiroyoshi Miyahara, Kenichi Yamashita, Makoto Takagi & Hiroki Kondo
Pages: 1429-1432
Published online: 07 Feb 2007
AbstractforBASE MUTATION ANALYSIS BY A FERROCENYL NAPHTHALENE DIIMIDE DERIVATIVE | Full Text | References | PDF (83.3 KB)
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CYTARABINE TREATMENT OF HUMAN T-LYMPHOID CELLS INDUCES DECREASED HIV-1 RECEPTOR EXPRESSION AND REDUCED HIV-1 SUSCEPTIBILITY
B. Gröschel, A. Kaufmann, J. Cinatl & H. W. Doerr
Pages: 1433-1437
Published online: 07 Feb 2007
AbstractforCYTARABINE TREATMENT OF HUMAN T-LYMPHOID CELLS INDUCES DECREASED HIV-1 RECEPTOR EXPRESSION AND REDUCED HIV-1 SUSCEPTIBILITY | Full Text | References | PDF (135.2 KB)
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