Nucleosides, Nucleotides & Nucleic Acids, Volume 26, Issue 10-12 (2007)

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Nucleosides, Nucleotides & Nucleic Acids, Volume 26, Issue 10-12 (2007)

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Original Articles

Article
Kinetics of C. Elegans DcpS Cap Hydrolysis Studied by Fluorescence Spectroscopy
J. Wierzchowski, M. Pietrzak, J. Stepinski, J. Jemielity, M. Kalek, E. Bojarska, M. Jankowska-Anyszka, R. E. Davis & E. Darzynkiewicz
Pages: 1211-1215
Published online: 05 Dec 2007
AbstractforKinetics of C. Elegans DcpS Cap Hydrolysis Studied by Fluorescence Spectroscopy | Full Text | References | PDF (79.5 KB)
  • 99 Views
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Article
Synthesis of C8-Modified 2″-Deoxyadenosine with Carcinogenic Arylamines
M. I. Jacobsen & C. Meier
Pages: 1217-1220
Published online: 05 Dec 2007
AbstractforSynthesis of C8-Modified 2″-Deoxyadenosine with Carcinogenic Arylamines | Full Text | References | PDF (86 KB)
  • 91 Views
  • 2 CrossRef citations
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Article
Polyaza Crown Ether as Non-Nucleosidic Building Blocks in DNA-Conjugates
Ulla Jakobsen, Katja Rohr, Rasmus K. Madsen & Stefan Vogel
Pages: 1221-1224
Published online: 05 Dec 2007
AbstractforPolyaza Crown Ether as Non-Nucleosidic Building Blocks in DNA-Conjugates | Full Text | References | PDF (216.5 KB)
  • 65 Views
  • 4 CrossRef citations
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Article
Synthesis and Biophysical Characterization of G-Rich Oligonucleotides Conjugated with Sugar-Phosphate Tails
J. D'Onofrio, E. Erra, G. Di Fabio, A. Iadonisi, L. Petraccone, L. De Napoli, G. Barone, J. Balzarini, C. Giancola & D. Montesarchio
Pages: 1225-1229
Published online: 05 Dec 2007
AbstractforSynthesis and Biophysical Characterization of G-Rich Oligonucleotides Conjugated with Sugar-Phosphate Tails | Full Text | References | PDF (323.2 KB)
  • 86 Views
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Article
Synthesis and Characterization of Tetra-End Linked Oligonucleotides Capable of Forming Monomolecular G-Quadruplexes
Nicola Borbone, Giorgia Oliviero, Jussara Amato, Stefano D'Errico, Aldo Galeone, Gennaro Piccialli & Luciano Mayol
Pages: 1231-1236
Published online: 05 Dec 2007
AbstractforSynthesis and Characterization of Tetra-End Linked Oligonucleotides Capable of Forming Monomolecular G-Quadruplexes | Full Text | References | PDF (659.3 KB)
  • 56 Views
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Article
Synthesis Study of 2′-O-(2-Methoxyethyl)-Purine Derivatives
Grigorii G. Sivets
Pages: 1237-1240
Published online: 05 Dec 2007
AbstractforSynthesis Study of 2′-O-(2-Methoxyethyl)-Purine Derivatives | Full Text | References | PDF (60.1 KB)
  • 277 Views
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Article
Synthesis of L-2′-Deoxypentofuranonucleoside Derivatives of Thymine From D-Glucose
Grigorii G. Sivets
Pages: 1241-1244
Published online: 05 Dec 2007
AbstractforSynthesis of L-2′-Deoxypentofuranonucleoside Derivatives of Thymine From D-Glucose | Full Text | References | PDF (68.5 KB)
  • 198 Views
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Article
Novel CoA-Polyamine Conjugates for Effective Inhibition of Spermine/Spermidine-N1-Acetyltransferase
Alina Simonian, Alex Khomutov, Tapani Hyvonen, Nikolay Grigorenko, Tuomo Keinanen, Jouko Vepsalainen, Leena Alhonen & Juhani Janne
Pages: 1245-1248
Published online: 05 Dec 2007
AbstractforNovel CoA-Polyamine Conjugates for Effective Inhibition of Spermine/Spermidine-N1-Acetyltransferase | Full Text | References | PDF (68 KB)
  • 111 Views
  • 4 CrossRef citations
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Article
Efficient Synthesis of Benzamide Riboside, a Potential Anticancer Agent
Laurent F. Bonnac, Guang-Yao Gao, Liqiang Chen, Steven E. Patterson, Hiremagalur N. Jayaram & Krzysztof W. Pankiewicz
Pages: 1249-1253
Published online: 05 Dec 2007
AbstractforEfficient Synthesis of Benzamide Riboside, a Potential Anticancer Agent | Full Text | References | PDF (78.7 KB)
  • 257 Views
  • 11 CrossRef citations
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Article
Fission Yeast Telomeric DNA Binding Protein Pot1 Has The Ability To Unfold Tetraplex Structure of Telomeric DNA
Hidetaka Torigoe
Pages: 1255-1260
Published online: 05 Dec 2007
AbstractforFission Yeast Telomeric DNA Binding Protein Pot1 Has The Ability To Unfold Tetraplex Structure of Telomeric DNA | Full Text | References | PDF (308.4 KB)
  • 39 Views
  • 3 CrossRef citations
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Article
Dual-Probe System Using Pyrenylmethyl-Modified Amino-Lna for Mismatch Detection
Tadashi Umemoto, Patrick J. Hrdlicka, B. Ravindra Babu & Jesper Wengel
Pages: 1261-1263
Published online: 05 Dec 2007
AbstractforDual-Probe System Using Pyrenylmethyl-Modified Amino-Lna for Mismatch Detection | Full Text | References | PDF (405.9 KB)
  • 63 Views
  • 3 CrossRef citations
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Article
Development of Artificial Restriction DNA Cutter Composed of Ce(Iv)/EDTA and PNA
Yoji Yamamoto, Akihiko Uehara, Kazuyuki Miura, Akira Watanabe, Hiroyuki Aburatani & Makoto Komiyama
Pages: 1265-1268
Published online: 05 Dec 2007
AbstractforDevelopment of Artificial Restriction DNA Cutter Composed of Ce(Iv)/EDTA and PNA | Full Text | References | PDF (671.1 KB)
  • 75 Views
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Article
Sulfur Containing Acyclovir Derivatives: Synthesis, Cytotoxic Activity, and Cell Phenotype Studies
Martins Ikaunieks, Irina Shestakova, Ilona Domracheva, Sergey Belyakov & Marina Madre
Pages: 1269-1271
Published online: 05 Dec 2007
AbstractforSulfur Containing Acyclovir Derivatives: Synthesis, Cytotoxic Activity, and Cell Phenotype Studies | Full Text | References | PDF (72.7 KB)
  • 46 Views
  • 1 CrossRef citations
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Article
A Convenient Solid-Phase Method for the Synthesis of Novel Oligonucleotide-Folate Conjugates
Eugenia V. Kazanova, Eugeny M. Zubin, Anna V. Kachalova, Eugeny M. Volkov, Tatiana S. Oretskaya, Dmitry A. Stetsenko & Marina B. Gottikh
Pages: 1273-1276
Published online: 05 Dec 2007
AbstractforA Convenient Solid-Phase Method for the Synthesis of Novel Oligonucleotide-Folate Conjugates | Full Text | References | PDF (167.8 KB)
  • 136 Views
  • 2 CrossRef citations
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Article
Stepwise Functionalization of Ribonucleopeptides: Optimization of the Response of Fluorescent Ribonucleopeptide Sensors for ATP
Tetsuya Hasegawa, Masaki Hagihara, Masatora Fukuda & Takashi Morii
Pages: 1277-1281
Published online: 05 Dec 2007
AbstractforStepwise Functionalization of Ribonucleopeptides: Optimization of the Response of Fluorescent Ribonucleopeptide Sensors for ATP | Full Text | References | PDF (658.3 KB)
  • 72 Views
  • 15 CrossRef citations
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Article
2′-O-Dimethylaminoethoxyuridine and 5-Dimethylaminopropargyl Deoxyuridine for at Base Pair Recognition in Triple Helices
Lavinia Brennan, Guomei Peng, Natarajan Srinivasan, Keith R. Fox & Tom Brown
Pages: 1283-1286
Published online: 05 Dec 2007
Abstractfor2′-O-Dimethylaminoethoxyuridine and 5-Dimethylaminopropargyl Deoxyuridine for at Base Pair Recognition in Triple Helices | Full Text | References | PDF (116.7 KB)
  • 272 Views
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Article
Oligonucleotide Synthesis Using Ionic Liquids as Soluble Supports
Robert A. Donga, Matthew Hassler, Tak-Hang Chan & Masad J. Damha
Pages: 1287-1293
Published online: 05 Dec 2007
AbstractforOligonucleotide Synthesis Using Ionic Liquids as Soluble Supports | Full Text | References | PDF (84 KB)
  • 356 Views
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Article
Optical Tweezers as a Probe for Oligodeoxyribonucleotide Structuration
Nicola Borbone, Giorgia Oliviero, Jussara Amato, Gennaro Piccialli, Luciano Mayol, Lisa Miccio, Giuseppe Pescen & Antonio Sasso
Pages: 1295-1299
Published online: 05 Dec 2007
AbstractforOptical Tweezers as a Probe for Oligodeoxyribonucleotide Structuration | Full Text | References | PDF (523.9 KB)
  • 53 Views
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Article
Assignment of the Absolute Configuration of P-Chiral 5′Mrna Cap Analogues Containing Phosphorothioate Moiety
Joanna Kowalska, Magdalena Lewdorowicz, Joanna Zuberek, Elzbieta Bojarska, Janusz Stepinski, Ryszard Stolarski, Edward Darzynkiewicz & Jacek Jemielity
Pages: 1301-1305
Published online: 05 Dec 2007
AbstractforAssignment of the Absolute Configuration of P-Chiral 5′Mrna Cap Analogues Containing Phosphorothioate Moiety | Full Text | References | PDF (78.5 KB)
  • 53 Views
  • 1 CrossRef citations
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Article
dabPna: Design, Synthesis, And Dna Binding Studies
Giovanni N. Roviello, Domenica Musumeci, Maria Moccia, Mariangela Castiglione, Roberto Sapio, Margherita Valente, Enrico M. Bucci, Giuseppe Perretta & Carlo Pedone
Pages: 1307-1310
Published online: 05 Dec 2007
AbstractfordabPna: Design, Synthesis, And Dna Binding Studies | Full Text | References | PDF (64.7 KB)
  • 124 Views
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Article
2′,3′-Isopropylidene Group, A Molecular Scaffold to Study the Activity of Adenosine and Adenylate Deaminase on Adenosine Analogues Modified in the Ribose Moiety
Pierangela Ciuffreda, Laura Alessandrini & Enzo Santaniello
Pages: 1311-1313
Published online: 05 Dec 2007
Abstractfor2′,3′-Isopropylidene Group, A Molecular Scaffold to Study the Activity of Adenosine and Adenylate Deaminase on Adenosine Analogues Modified in the Ribose Moiety | Full Text | References | PDF (60.9 KB)
  • 62 Views
  • 3 CrossRef citations
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Article
Synthesis of 3H and 13C Labeled Mrna Cap Dinucleotides—Useful Tools for Nmr, Biochemical, and Biological Studies
Jacek Jemielity, Ryszard Stolarski & Edward Darzynkiewicz
Pages: 1315-1319
Published online: 05 Dec 2007
AbstractforSynthesis of 3H and 13C Labeled Mrna Cap Dinucleotides—Useful Tools for Nmr, Biochemical, and Biological Studies | Full Text | References | PDF (580.7 KB)
  • 103 Views
  • 2 CrossRef citations
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Article
Synthesis of A New Ribose Modified Analogue of Cyclic Inosine Diphosphate Ribose
Giorgia Oliviero, Nicola Borbone, Jussara Amato, Stefano D'Errico, Gennaro Piccialli, Michela Varra & Luciano Mayol
Pages: 1321-1324
Published online: 05 Dec 2007
AbstractforSynthesis of A New Ribose Modified Analogue of Cyclic Inosine Diphosphate Ribose | Full Text | References | PDF (75.4 KB)
  • 58 Views
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Article
New Developments of the “Lock-in” Modified cycloSal-d4TMPs
Dalibor Vukadinović-Tenter, Jan Balzarini & Chris Meier
Pages: 1325-1328
Published online: 05 Dec 2007
AbstractforNew Developments of the “Lock-in” Modified cycloSal-d4TMPs | Full Text | References | PDF (63.2 KB)
  • 92 Views
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Article
Solid-Supported Synthesis of 5′-mRNA CAP-4 from Trypanosomatids
Magdalena Lewdorowicz, Jacek Jemielity, Ryszard Kierzek, Michal Shapira, Janusz Stepinski & Edward Darzynkiewicz
Pages: 1329-1333
Published online: 05 Dec 2007
AbstractforSolid-Supported Synthesis of 5′-mRNA CAP-4 from Trypanosomatids | Full Text | References | PDF (238.3 KB)
  • 135 Views
  • 4 CrossRef citations
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Article
A Pyrimidopyrimidoindole Nucleoside (dCPPI): Photophysical Properties and Thermal Stability of the Modified Dna Duplexes
Masahiro Mizuta, Kohji Seio, Kenichi Miyata, Akihiro Ohkubo, Haruhiko Taguchi & Mitsuo Sekine
Pages: 1335-1338
Published online: 05 Dec 2007
AbstractforA Pyrimidopyrimidoindole Nucleoside (dCPPI): Photophysical Properties and Thermal Stability of the Modified Dna Duplexes | Full Text | References | PDF (188.6 KB)
  • 55 Views
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Article
Synthesis of Leishmania Cap-4 Intermediates, Cap-2 and Cap-3
Magdalena Lewdorowicz, Janusz Stepinski, Ryszard Kierzek, Jacek Jemielity, Joanna Zuberek, Yael Yoffe, Michal Shapira, Ryszard Stolarski & Edward Darzynkiewicz
Pages: 1339-1348
Published online: 05 Dec 2007
AbstractforSynthesis of Leishmania Cap-4 Intermediates, Cap-2 and Cap-3 | Full Text | References | PDF (118.3 KB)
  • 464 Views
  • 2 CrossRef citations
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Article
Affinity of Dinucleotide Cap Analogues for Human Decapping Scavenger (hDcpS)
Zbigniew M. Darzynkiewicz, Elzbieta Bojarska, Janusz Stepinski, Jacek Jemielity, Marzena Jankowska-Anyszka, Richard E. Davis & Edward Darzynkiewicz
Pages: 1349-1352
Published online: 05 Dec 2007
AbstractforAffinity of Dinucleotide Cap Analogues for Human Decapping Scavenger (hDcpS) | Full Text | References | PDF (66.3 KB)
  • 117 Views
  • 9 CrossRef citations
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Article
Evaluation of Different Chemical Strategies for Conjugation of Oligonucleotides to Peptides
Igor A. Kozlov, Peter C. Melnyk, John P. Hachmann, David L. Barker, Michal Lebl & Chanfeng Zhao
Pages: 1353-1357
Published online: 05 Dec 2007
AbstractforEvaluation of Different Chemical Strategies for Conjugation of Oligonucleotides to Peptides | Full Text | References | PDF (244.6 KB)
  • 149 Views
  • 6 CrossRef citations
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Article
Synthesis and Incorporation of a Simple Acyclic Furan Containing Phosphoramidite
K. Stevens & A. Madder
Pages: 1359-1362
Published online: 05 Dec 2007
AbstractforSynthesis and Incorporation of a Simple Acyclic Furan Containing Phosphoramidite | Full Text | References | PDF (66.3 KB)
  • 96 Views
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Article
Cg Base Pair Recognition Within Dna Triple Helices Using N-Methyl-3H-Pyrrolo[2,3-d]Pyrimidin-2(7H)-One Nucleoside Analogues
Simon R. Gerrard, Natarajan Srinivasan, Keith R. Fox & Tom Brown
Pages: 1363-1367
Published online: 05 Dec 2007
AbstractforCg Base Pair Recognition Within Dna Triple Helices Using N-Methyl-3H-Pyrrolo[2,3-d]Pyrimidin-2(7H)-One Nucleoside Analogues | Full Text | References | PDF (86.4 KB)
  • 108 Views
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Article
Looking for New Pyrimidine Acyclic Nucleotide Analogues Designed for Phosphorylation by Human Ump-Cmp Kinase
Dimitri Topalis, Hiroki Kumamoto, Julie A. C. Alexandre, Laurence Dugué, Sylvie Pochet, Sabine Berteina-Raboin, Luigi A. Agrofoglio & Dominique Deville-Bonne
Pages: 1369-1373
Published online: 05 Dec 2007
AbstractforLooking for New Pyrimidine Acyclic Nucleotide Analogues Designed for Phosphorylation by Human Ump-Cmp Kinase | Full Text | References | PDF (120.3 KB)
  • 88 Views
  • 1 CrossRef citations
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Article
Enantio-Selectivity of Human Nucleoside Monophosphate Kinases
J. A. C. Alexandre, B. Roy, D. Topalis, C. Périgaud & D. Deville-Bonne
Pages: 1375-1379
Published online: 05 Dec 2007
AbstractforEnantio-Selectivity of Human Nucleoside Monophosphate Kinases | Full Text | References | PDF (64.4 KB)
  • 83 Views
  • 1 CrossRef citations
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Article
Synthesis of Pyrene Labeled Rna for Fluorescence Measurements
Taewoo Kwon, Nelly Piton, Christian Grünewald & Joachim W. Engels
Pages: 1381-1386
Published online: 05 Dec 2007
AbstractforSynthesis of Pyrene Labeled Rna for Fluorescence Measurements | Full Text | References | PDF (232.4 KB)
  • 154 Views
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Article
Synthesis of 9-(2,3-Dideoxy-2,3-Difluoro-β-D- Arabinofuranosyl)Adenine
Grigorii G. Sivets, Elena N. Kalinichenko & Igor A. Mikhailopulo
Pages: 1387-1389
Published online: 05 Dec 2007
AbstractforSynthesis of 9-(2,3-Dideoxy-2,3-Difluoro-β-D- Arabinofuranosyl)Adenine | Full Text | References | PDF (61.5 KB)
  • 82 Views
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Article
Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis
Julie Broggi, Nicolas Joubert, Vincent Aucagne, Sabine Berteina-Raboin, S. Diez-Gonzalez, Steve Nolan, Dimitri Topalis, Dominique Deville-Bonne, Jan Balzarini, Johan Neyts, Graciela Andrei, Robert Snoeck & Luigi A. Agrofoglio
Pages: 1391-1394
Published online: 05 Dec 2007
AbstractforAlkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis | Full Text | References | PDF (177.4 KB)
  • 185 Views
  • 17 CrossRef citations
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Article
Supported Synthesis and Functionnalization of 2″-Deoxyuridine by Suzuki-Miyaura Cross-Coupling
Saïd El Kazzouli, Sabine Berteina-Raboin & Luigi A. Agrofoglio
Pages: 1395-1398
Published online: 05 Dec 2007
AbstractforSupported Synthesis and Functionnalization of 2″-Deoxyuridine by Suzuki-Miyaura Cross-Coupling | Full Text | References | PDF (134.4 KB)
  • 134 Views
  • 7 CrossRef citations
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Article
Cross-Metathesis Mediated Synthesis of New Acyclic Nucleoside Phosphonates
Vincent Roy, Hiroki Kumamoto, Sabine Berteina-Raboin, Steven P. Nolan, Dimitri Topalis, Dominique Deville-Bonne, Jan Balzarini, Johan Neyts, Gracelia Andrei, Robert Snoeck & Luigi A. Agrofoglio
Pages: 1399-1402
Published online: 05 Dec 2007
AbstractforCross-Metathesis Mediated Synthesis of New Acyclic Nucleoside Phosphonates | Full Text | References | PDF (96.2 KB)
  • 99 Views
  • 3 CrossRef citations
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Article
Synthesis and Biophysical Studies of N2′-Functionalized 2′-Amino-α-L-LNA
T. Santhosh Kumar, Andreas S. Madsen, Jesper Wengel & Patrick J. Hrdlicka
Pages: 1403-1405
Published online: 05 Dec 2007
AbstractforSynthesis and Biophysical Studies of N2′-Functionalized 2′-Amino-α-L-LNA | Full Text | References | PDF (71.1 KB)
  • 67 Views
  • 4 CrossRef citations
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Article
Pyrene-Functionalized 2 ′-Amino-α-L-LNA as Potential Diagnostic Probes
T. Santhosh Kumar, Jesper Wengel & Patrick J. Hrdlicka
Pages: 1407-1409
Published online: 05 Dec 2007
AbstractforPyrene-Functionalized 2 ′-Amino-α-L-LNA as Potential Diagnostic Probes | Full Text | References | PDF (73.3 KB)
  • 42 Views
  • 4 CrossRef citations
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Article
Triplex-Forming Ability of Modified Oligonucleotides
Torben H⊘jland, B. Ravindra Babu, Torsten Bryld & Jesper Wengel
Pages: 1411-1414
Published online: 05 Dec 2007
AbstractforTriplex-Forming Ability of Modified Oligonucleotides | Full Text | References | PDF (76.8 KB)
  • 77 Views
  • 6 CrossRef citations
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Article
N2′-Functionalized 2′-Amino-α-L-LNA Adenine Derivatives—Efficient Targeting of Single Stranded DNA
Nicolai K. Andersen, Jesper Wengel & Patrick J. Hrdlicka
Pages: 1415-1417
Published online: 05 Dec 2007
AbstractforN2′-Functionalized 2′-Amino-α-L-LNA Adenine Derivatives—Efficient Targeting of Single Stranded DNA | Full Text | References | PDF (65.1 KB)
  • 78 Views
  • 7 CrossRef citations
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Article
Toward a Catalytic Site in DNA: Polyaza Crown Ether as Non-Nucleosidic Building Blocks in DNA Conjugates
Ulla Jakobsen, Katja Rohr & Stefan Vogel
Pages: 1419-1422
Published online: 05 Dec 2007
AbstractforToward a Catalytic Site in DNA: Polyaza Crown Ether as Non-Nucleosidic Building Blocks in DNA Conjugates | Full Text | References | PDF (688.4 KB)
  • 166 Views
  • 31 CrossRef citations
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Article
Cu2+TerPy Complexes as Catalysts of the Cleavage of the 5′-cap Structure of mRNA
Leena Maanpää, Sharmin Taherpour, Zhibo Zhang, Clemence Guillaume, Istvan Szilagy, Esa Mäki & Satu Mikkola
Pages: 1423-1426
Published online: 05 Dec 2007
AbstractforCu2+TerPy Complexes as Catalysts of the Cleavage of the 5′-cap Structure of mRNA | Full Text | References | PDF (64.2 KB)
  • 55 Views
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Article
Survivin mRNA Antagonists Using Locked Nucleic Acid, Potential for Molecular Cancer Therapy
Niels Fisker, Majken Westergaard, Henrik Frydenlund Hansen & Jens Bo Hansen
Pages: 1427-1430
Published online: 05 Dec 2007
AbstractforSurvivin mRNA Antagonists Using Locked Nucleic Acid, Potential for Molecular Cancer Therapy | Full Text | References | PDF (395.8 KB)
  • 83 Views
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Article
Synthesis of 1′-C-Fluoromethyladenosine
Annelaure Damont, David Dukhan, Gilles Gosselin, Jérôme Peyronnet & Richard Storer
Pages: 1431-1434
Published online: 05 Dec 2007
AbstractforSynthesis of 1′-C-Fluoromethyladenosine | Full Text | References | PDF (174.1 KB)
  • 281 Views
  • 8 CrossRef citations
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Article
Synthesis of Nucleosides with Additional Nucleobases
Charlotte Andersen, S⊘ren L. Pedersen & Poul Nielsen
Pages: 1435-1438
Published online: 05 Dec 2007
AbstractforSynthesis of Nucleosides with Additional Nucleobases | Full Text | References | PDF (146.8 KB)
  • 123 Views
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Article
Synthesis and Stability Studies of 2′,3′,5′-tri-O-Acetyl-2-Amino(-N6-Cyclopentyl)-1-Deazaadenosines
Sauro Vittori, Ram Chandra Mishra, Diego Dal Ben, Dhuldeo Kachare, Catia Lambertucci, Rosaria Volpini & Gloria Cristalli
Pages: 1439-1442
Published online: 05 Dec 2007
AbstractforSynthesis and Stability Studies of 2′,3′,5′-tri-O-Acetyl-2-Amino(-N6-Cyclopentyl)-1-Deazaadenosines | Full Text | References | PDF (97 KB)
  • 53 Views
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Article
Synthesis and Biological Activity of Trisubstituted Adenines as A2A Adenosine Receptor Antagonists
Catia Lambertucci, Sauro Vittori, Ram Chandra Mishra, Diego Dal Ben, Karl-Norbert Klotz, Rosaria Volpini & Gloria Cristalli
Pages: 1443-1446
Published online: 05 Dec 2007
AbstractforSynthesis and Biological Activity of Trisubstituted Adenines as A2A Adenosine Receptor Antagonists | Full Text | References | PDF (82.3 KB)
  • 68 Views
  • 14 CrossRef citations
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Article
Bent Oligonucleotide Duplexes as HMGB1 Inhibitors: a Comparative Study
D. Musumeci, G. N. Roviello, M. Moccia, C. Pedone, E. M. Bucci, R. Sapio, M. Valente & S. Fumero
Pages: 1447-1450
Published online: 05 Dec 2007
AbstractforBent Oligonucleotide Duplexes as HMGB1 Inhibitors: a Comparative Study | Full Text | References | PDF (72.4 KB)
  • 57 Views
  • 6 CrossRef citations
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Article
Solid-Phase Synthesis of Modified RNAs Containing Amide-Linked Oligoribonucleosides at Their 3′-End and Their Application to siRNA
Reiko Iwase, Takaaki Toyama & Kengo Nishimori
Pages: 1451-1454
Published online: 05 Dec 2007
AbstractforSolid-Phase Synthesis of Modified RNAs Containing Amide-Linked Oligoribonucleosides at Their 3′-End and Their Application to siRNA | Full Text | References | PDF (96.5 KB)
  • 156 Views
  • 28 CrossRef citations
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Article
Synthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an H-Phosphonate Approach
Hongyan Liu, Syed N. Hashmi & Barbara Ramsay Shaw
Pages: 1455-1457
Published online: 05 Dec 2007
AbstractforSynthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an H-Phosphonate Approach | Full Text | References | PDF (106.9 KB)
  • 114 Views
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Article
Labeling of Oligonucleotides with DTPA and DOTA on Solid Phase
Jari Hovinen
Pages: 1459-1462
Published online: 05 Dec 2007
AbstractforLabeling of Oligonucleotides with DTPA and DOTA on Solid Phase | Full Text | References | PDF (120.7 KB)
  • 189 Views
  • 4 CrossRef citations
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Article
Triplex Formation-Based Artificial Transcription Factor to Regulate Target Gene Expression
Hidetaka Torigoe, Takuma Katayama & Yusuke Tsukamoto
Pages: 1463-1466
Published online: 05 Dec 2007
AbstractforTriplex Formation-Based Artificial Transcription Factor to Regulate Target Gene Expression | Full Text | References | PDF (477.8 KB)
  • 65 Views
  • 3 CrossRef citations
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Article
Synthesis of Aminomethyl- and Bis-Aminomethyl-Fluorescein Energy Transfer Terminators
Sudhakar Rao Takkellapati, Chung Y. Chen, Vladimir Neschadimenko, Satyam Nampalli, Haiguang Xiao, Jeffrey Wegener, Prasad Dhulipala, Shiv Kumar & Carl Fuller
Pages: 1467-1470
Published online: 05 Dec 2007
AbstractforSynthesis of Aminomethyl- and Bis-Aminomethyl-Fluorescein Energy Transfer Terminators | Full Text | References | PDF (177.7 KB)
  • 189 Views
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Article
2-5A Ligands—A New Concept for the Treatment of Prostate Cancer
Hagen Cramer, James R. Okicki, Taikyun Rho, Xinning Wang, Robert H. Silverman & Warren D. W. Heston
Pages: 1471-1477
Published online: 05 Dec 2007
Abstractfor2-5A Ligands—A New Concept for the Treatment of Prostate Cancer | Full Text | References | PDF (218.2 KB)
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Article
RNA Cleavage by 2,9-Diamino-1,10-Phenanthroline PNA Conjugates
Merita Murtola, Dimitri Ossipov, Jessica Sandbrink & Roger Strömberg
Pages: 1479-1483
Published online: 05 Dec 2007
AbstractforRNA Cleavage by 2,9-Diamino-1,10-Phenanthroline PNA Conjugates | Full Text | References | PDF (213.3 KB)
  • 329 Views
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Article
Solid Support Post-Conjugation of Amino Acids and a Phenanthroline Derivative to a Central Position in Peptide Nucleic Acids
Jessica Sandbrink, Merita Murtola & Roger Strömberg
Pages: 1485-1489
Published online: 05 Dec 2007
AbstractforSolid Support Post-Conjugation of Amino Acids and a Phenanthroline Derivative to a Central Position in Peptide Nucleic Acids | Full Text | References | PDF (129.6 KB)
  • 182 Views
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Article
Evaluation of Lactam Protection for Synthesis of 2′-O-Alkylated Uridines
Stefan Milton & Roger Strömberg
Pages: 1491-1493
Published online: 05 Dec 2007
AbstractforEvaluation of Lactam Protection for Synthesis of 2′-O-Alkylated Uridines | Full Text | References | PDF (98.4 KB)
  • 157 Views
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Article
Synthesis of A 2′-O-(Carbomoylmethyl)Ribonucleoside H-Phosphonate Building Block and A Model Dinucleotide
Stefan Milton, Raunak Esther Yeheskiely & Roger Strömberg
Pages: 1495-1499
Published online: 05 Dec 2007
AbstractforSynthesis of A 2′-O-(Carbomoylmethyl)Ribonucleoside H-Phosphonate Building Block and A Model Dinucleotide | Full Text | References | PDF (170 KB)
  • 108 Views
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Article
Evaluating Coupling Procedures for Synthesis of Lna-Peptide Conjugates
Peter Steunenberg, Hans Leijonmarck, Mathias G. Svahn, C. I. Edvard Smith & Roger Strömberg
Pages: 1501-1504
Published online: 05 Dec 2007
AbstractforEvaluating Coupling Procedures for Synthesis of Lna-Peptide Conjugates | Full Text | References | PDF (83.7 KB)
  • 66 Views
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Article
Synthesis of A Branched Locked Nucleic Acid (LNA) Analogue
Pawan K. Sharma, Surender Kumar & Poul Nielsen
Pages: 1505-1508
Published online: 05 Dec 2007
AbstractforSynthesis of A Branched Locked Nucleic Acid (LNA) Analogue | Full Text | References | PDF (122 KB)
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Article
2′-O-Hydroxyalkoxymethylribonucleosides and their Incorporation into Oligoribonucleotides
Sergey N. Mikhailov, Georgii V. Bobkov, Kyrill V. Brilliantov, Jef Rozenski, Arthur Van Aerschot, Piet Herdewijn, Michael H. Fisher & Rudolph L. Juliano
Pages: 1509-1512
Published online: 05 Dec 2007
Abstractfor2′-O-Hydroxyalkoxymethylribonucleosides and their Incorporation into Oligoribonucleotides | Full Text | References | PDF (105.1 KB)
  • 54 Views
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Article
Improvement of the Synthesis of Sugar Phosphonates Using Microwave Irradiations
Suzanne Peyrottes, Franck Gallier, Alain Papillaud, Jérôme Béjaud & Christian Périgaud
Pages: 1513-1515
Published online: 05 Dec 2007
AbstractforImprovement of the Synthesis of Sugar Phosphonates Using Microwave Irradiations | Full Text | References | PDF (75.5 KB)
  • 112 Views
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Article
Novel Selective Biocatalytic Deacylation Studies on Key Precursors for Bicyclonucleosides
Ashok K. Prasad, Sunil K. Singh, Neerja Kalra, Nidhi Singhal, Jesper Wengel & Virinder S. Parmar
Pages: 1517-1521
Published online: 05 Dec 2007
AbstractforNovel Selective Biocatalytic Deacylation Studies on Key Precursors for Bicyclonucleosides | Full Text | References | PDF (209.9 KB)
  • 100 Views
  • 3 CrossRef citations
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Article
Mass Spectrometry Based Methods for Analysis of Nucleosides as Antiviral Drugs and Potential Tumor Biomarkers
Luigi A. Agrofoglio, Vincent Bezy, Patrick Chaimbault, Raphaël Delépée, Boutaina Rhourri & Philippe Morin
Pages: 1523-1527
Published online: 05 Dec 2007
AbstractforMass Spectrometry Based Methods for Analysis of Nucleosides as Antiviral Drugs and Potential Tumor Biomarkers | Full Text | References | PDF (172.5 KB)
  • 166 Views
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Article
Two Carbocyclic Locked Nucleic Acid Analogues Give Structural Information about the Role of Hydration in A-Type Duplexes
Nanna Albæk, Michael Petersen & Poul Nielsen
Pages: 1529-1532
Published online: 05 Dec 2007
AbstractforTwo Carbocyclic Locked Nucleic Acid Analogues Give Structural Information about the Role of Hydration in A-Type Duplexes | Full Text | References | PDF (129.6 KB)
  • 113 Views
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Article
Porphyrin-DNA: A Supramolecular Scaffold for Functional Molecules on the Nanometre Scale
Imenne Bouamaied, Leslie-Anne Fendt, Daniel Häussinger, Markus Wiesner, Sandra Thöni, Nicolas Amiot & Eugen Stulz
Pages: 1533-1538
Published online: 05 Dec 2007
AbstractforPorphyrin-DNA: A Supramolecular Scaffold for Functional Molecules on the Nanometre Scale | Full Text | References | PDF (178.2 KB)
  • 131 Views
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Article
New Pseudonucleosides Containing Chiral Oxazolidin-2-Ones and Cyclosulfamides as Aglycones: Synthesis and Antiviral Evaluation
Hocine Bouleghlem, Malika Berredjem, Marc Lecouvey & Nour-Eddine Aouf
Pages: 1539-1542
Published online: 05 Dec 2007
AbstractforNew Pseudonucleosides Containing Chiral Oxazolidin-2-Ones and Cyclosulfamides as Aglycones: Synthesis and Antiviral Evaluation | Full Text | References | PDF (115 KB)
  • 208 Views
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Article
2′-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine: A Nucleoside Reverse Transcriptase Inhibitor with Highly Potent Activity Against Wide Spectrum of HIV-1 Strains, Favorable Toxic Profiles, and Stability in Plasma
Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi Kodama, Masao Matsuoka, Tomohiro Nakata & Hiroaki Mitsuya
Pages: 1543-1546
Published online: 05 Dec 2007
Abstractfor2′-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine: A Nucleoside Reverse Transcriptase Inhibitor with Highly Potent Activity Against Wide Spectrum of HIV-1 Strains, Favorable Toxic Profiles, and Stability in Plasma | Full Text | References | PDF (58.3 KB)
  • 227 Views
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Article
NMR Study of Ammonium Ion Binding to d[G3T4G4]2 and d[G4(T4G4)3] G-Quadruplexes
Peter Podbevšek, Primož Šket & Janez Plavec
Pages: 1547-1551
Published online: 05 Dec 2007
AbstractforNMR Study of Ammonium Ion Binding to d[G3T4G4]2 and d[G4(T4G4)3] G-Quadruplexes | Full Text | References | PDF (283.8 KB)
  • 60 Views
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Article
Antiviral Activity of 3-(3,5-Dimethylbenzyl)Uracil Derivatives Against Hiv-1 and HCMV
Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei & Erik De Clercq
Pages: 1553-1558
Published online: 05 Dec 2007
AbstractforAntiviral Activity of 3-(3,5-Dimethylbenzyl)Uracil Derivatives Against Hiv-1 and HCMV | Full Text | References | PDF (72.9 KB)
  • 72 Views
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Article
Sequence-Specific Recognition of Double-Stranded DNA by Synthetic Minor Groove Binder Conjugates. toward the Construction of Artificial Site-Specific Deoxyribonucleases
Alexandre S. Boutorine, Ludovic Halby, Philippe Simon, Loïc Perrouault, Carine Giovannangeli, Georgy V. Gursky, Anna N. Surovaya, Sergueï L. Grokhovsky, Vladimir A. Ryabinin & Alexandre N. Sinyakov
Pages: 1559-1563
Published online: 05 Dec 2007
AbstractforSequence-Specific Recognition of Double-Stranded DNA by Synthetic Minor Groove Binder Conjugates. toward the Construction of Artificial Site-Specific Deoxyribonucleases | Full Text | References | PDF (181.2 KB)
  • 56 Views
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Article
Design, Synthesis, and Anti-Tumor Activity of 4′-Thionucleosides as Potent and Selective Agonists at the Human A3 Adenosine Receptor
Lak Shin Jeong, Hyuk Woo Lee, Hea Ok Kim, Ji Young Jung, Prashantha Gunaga, Sang Kook Lee, Eun-Jin Lee, Moon Woo Chun, Zhan-Guo Gao, Kenneth A. Jacobson & Hyung Ryong Moon
Pages: 1565-1568
Published online: 05 Dec 2007
AbstractforDesign, Synthesis, and Anti-Tumor Activity of 4′-Thionucleosides as Potent and Selective Agonists at the Human A3 Adenosine Receptor | Full Text | References | PDF (139.1 KB)
  • 90 Views
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Article
Mismatch Discrimination of Base-Modified Nucleic Acids and their Constituents: Non-Watson-Crick Base Pairing Induced by Tautomerization
Frank Seela, Xiaohua Peng & Kuiying Xu
Pages: 1569-1572
Published online: 05 Dec 2007
AbstractforMismatch Discrimination of Base-Modified Nucleic Acids and their Constituents: Non-Watson-Crick Base Pairing Induced by Tautomerization | Full Text | References | PDF (169.4 KB)
  • 99 Views
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Article
Novel Fluorophores for Labeling of Nucleosides and Oligonucleotides
Shipra Singh & Ramendra K. Singh
Pages: 1573-1576
Published online: 05 Dec 2007
AbstractforNovel Fluorophores for Labeling of Nucleosides and Oligonucleotides | Full Text | References | PDF (159.1 KB)
  • 75 Views
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Article
Oligonucleotide Conjugate GRN163L Targeting Human Telomerase as Potential Anticancer and Antimetastatic Agent
Sergei M. Gryaznov, Shalmica Jackson, Gunnur Dikmen, Calvin Harley, Brittney-Shea Herbert, Woodring E. Wright & Jerry W. Shay
Pages: 1577-1579
Published online: 05 Dec 2007
AbstractforOligonucleotide Conjugate GRN163L Targeting Human Telomerase as Potential Anticancer and Antimetastatic Agent | Full Text | References | PDF (327.1 KB)
  • 160 Views
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Article
DNA Labelling Topologies for Monitoring DNA-Protein Complex Formation by Fluorescence Anisotropy
Matthias Bahr, Linda Valis, Hans-Achim Wagenknecht & Elmar Weinhold
Pages: 1581-1584
Published online: 05 Dec 2007
AbstractforDNA Labelling Topologies for Monitoring DNA-Protein Complex Formation by Fluorescence Anisotropy | Full Text | References | PDF (1.9 MB)
  • 116 Views
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Article
Thiazole Orange: A Useful Probe for Fluorescence Sensing of G-Quadruplex–Ligand Interactions
D. Monchaud, C. Allain & M.-P. Teulade-Fichou
Pages: 1585-1588
Published online: 05 Dec 2007
AbstractforThiazole Orange: A Useful Probe for Fluorescence Sensing of G-Quadruplex–Ligand Interactions | Full Text | References | PDF (348.4 KB)
  • 822 Views
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Article
Biophysical Stability and Enzymatic Recognition of Oxanine in Dna
Seung Pil Pack, Akihiro Doi, Mitsuru Nonogawa, Nagendra K. Kamisetty, Kamakshaiah C. Devarayapalli, Tsutomu Kodaki & Keisuke Makino
Pages: 1589-1593
Published online: 05 Dec 2007
AbstractforBiophysical Stability and Enzymatic Recognition of Oxanine in Dna | Full Text | References | PDF (378.8 KB)
  • 29 Views
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Article
Synthesis and Properties of Pyrrolidine-Based Negatively Charged Dna Mimics
Vladimir A. Efimov, Valeryi N. Klykov & Oksana G. Chakhmakhcheva
Pages: 1595-1599
Published online: 05 Dec 2007
AbstractforSynthesis and Properties of Pyrrolidine-Based Negatively Charged Dna Mimics | Full Text | References | PDF (256 KB)
  • 90 Views
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Article
5-Methylcytosine-Selective Osmium Oxidation
Akimitsu Okamoto
Pages: 1601-1604
Published online: 05 Dec 2007
Abstractfor5-Methylcytosine-Selective Osmium Oxidation | Full Text | References | PDF (414.1 KB)
  • 83 Views
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Article
A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
Ramon Eritja, Anna Aviñó, Beatriz G. de la Torre, Donald Fitzmaurice, Andrea Ongaro, Sarmiza Elena Stanca, Andrea DiSalvo, Brendan Maninng & Daniela Iacopino
Pages: 1605-1609
Published online: 05 Dec 2007
AbstractforA Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives | Full Text | References | PDF (516.8 KB)
  • 45 Views
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Article
2′-Deoxyadenosine Bearing Hydrophobic Carborane Pharmacophore
Agnieszka Olejniczak, Blażej Wojtczak & Zbigniew J. Lesnikowski
Pages: 1611-1613
Published online: 05 Dec 2007
Abstractfor2′-Deoxyadenosine Bearing Hydrophobic Carborane Pharmacophore | Full Text | References | PDF (122.5 KB)
  • 137 Views
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Article
Highly Effective Non-Explosive Activators Based on Saccharin for the Synthesis of Oligonucleotides and Phosphoramidites
Nanda D. Sinha, Patrick Foster, Satya N. Kuchimanchi, Greg Miranda, Saied Shaikh & Dennis Michaud
Pages: 1615-1618
Published online: 05 Dec 2007
AbstractforHighly Effective Non-Explosive Activators Based on Saccharin for the Synthesis of Oligonucleotides and Phosphoramidites | Full Text | References | PDF (103.6 KB)
  • 126 Views
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Article
In Vivo and in Vitro Activity And Mechanism Of Action of the Multidrug Cytarabine-L-Glycerylyl-Fluorodeoxyuridine
Irene V. Bijnsdorp, Reto A. Schwendener, Herbert Schott, Iduna Fichtner, Kees Smid, Sarah Schott, Adrie C. Laan & Godefridus J. Peters
Pages: 1619-1624
Published online: 05 Dec 2007
AbstractforIn Vivo and in Vitro Activity And Mechanism Of Action of the Multidrug Cytarabine-L-Glycerylyl-Fluorodeoxyuridine | Full Text | References | PDF (105.9 KB)
  • 111 Views
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Article
2′,4′-BNANC: A Novel Bridged Nucleic Acid Analogue with Excellent Hybridizing and Nuclease Resistance Profiles
S. M. Abdur Rahman, Sayori Seki, Kazushige Utsuki, Satoshi Obika, Kazuyuki Miyashita & Takeshi Imanishi
Pages: 1625-1628
Published online: 05 Dec 2007
Abstractfor2′,4′-BNANC: A Novel Bridged Nucleic Acid Analogue with Excellent Hybridizing and Nuclease Resistance Profiles | Full Text | References | PDF (75 KB)
  • 113 Views
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Article
Mass Spectrometry of Oligonucleotides
Stefan Schürch, Jan M. Tromp & Selina T. M. Monn
Pages: 1629-1633
Published online: 05 Dec 2007
AbstractforMass Spectrometry of Oligonucleotides | Full Text | References | PDF (630 KB)
  • 276 Views
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Article
Mismatch Base Pair Detection by Fluorescence Spectral Change Upon Addition of Metal Cation—Toward Efficient Analysis of Single Nucleotide Polymorphism
Hidetaka Torigoe, Akira Ono & Tetsuo Kozasa
Pages: 1635-1639
Published online: 05 Dec 2007
AbstractforMismatch Base Pair Detection by Fluorescence Spectral Change Upon Addition of Metal Cation—Toward Efficient Analysis of Single Nucleotide Polymorphism | Full Text | References | PDF (216.7 KB)
  • 68 Views
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Article
The Effect of INA [(R)-1-O-(1-Pyrenylmethyl)Glycerol] Insertions on the Structure and Biological Activity of a G-Quadruplex from a Critical Kras G-Rich Sequence
Susanna Cogoi, Manikandan Paramasivan, L. E. Xodo, Vyacheslav V. Filichev & Erik B. Pedersen
Pages: 1641-1643
Published online: 05 Dec 2007
AbstractforThe Effect of INA [(R)-1-O-(1-Pyrenylmethyl)Glycerol] Insertions on the Structure and Biological Activity of a G-Quadruplex from a Critical Kras G-Rich Sequence | Full Text | References | PDF (147 KB)
  • 59 Views
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Article
At Tachment of Cholesterol to Amino-LNA: Synthesis and Hybridization Properties
Torsten Bryld & Christian Lomholt
Pages: 1645-1647
Published online: 05 Dec 2007
AbstractforAt Tachment of Cholesterol to Amino-LNA: Synthesis and Hybridization Properties | Full Text | References | PDF (114.4 KB)
  • 86 Views
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Article
Solid Phase Synthesis of Nucleobase and Ribose Modified Inosine Nucleoside Analogues
Giorgia Oliviero, Jussara Amato, Stefano D'Errico, Nicola Borbone, Gennaro Piccialli & Luciano Mayol
Pages: 1649-1652
Published online: 05 Dec 2007
AbstractforSolid Phase Synthesis of Nucleobase and Ribose Modified Inosine Nucleoside Analogues | Full Text | References | PDF (127.3 KB)
  • 119 Views
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Article
Asymmetric Synthesis and Biological Activity of l-Bicyclocarba-d4T
Hyung Ryong Moon, Ah-Young Park, Kyung Ran Kim, Moon Woo Chun & Lak Shin Jeong
Pages: 1653-1657
Published online: 05 Dec 2007
AbstractforAsymmetric Synthesis and Biological Activity of l-Bicyclocarba-d4T | Full Text | References | PDF (179.5 KB)
  • 93 Views
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Article
Homogeneous Fluorescence Assays for RNA Diagnosis by Pyrene-Conjugated 2′-O-Methyloligoribonucleotides
Takashi Sakamoto, Akio Kobori, Masako Shigezawa, Yasutaka Amitani, Maiko Higuchi & Akira Murakami
Pages: 1659-1664
Published online: 05 Dec 2007
AbstractforHomogeneous Fluorescence Assays for RNA Diagnosis by Pyrene-Conjugated 2′-O-Methyloligoribonucleotides | Full Text | References | PDF (279.8 KB)
  • 52 Views
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Article
A Simple Nucleic Acid Alternative: Aminopropyl Nucleic Acids (APNAs)
Ding Zhou, Guy Schepers & Arthur Van Aerschot
Pages: 1665-1668
Published online: 05 Dec 2007
AbstractforA Simple Nucleic Acid Alternative: Aminopropyl Nucleic Acids (APNAs) | Full Text | References | PDF (78.6 KB)
  • 48 Views
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Article
Detection of Terminal Mismatches on DNA Duplexes in Homogeneous Assays or with Immobilized Probes
Marcel Chassignol, Yves Aubert, Victoria Roig & Ulysse Asseline
Pages: 1669-1672
Published online: 05 Dec 2007
AbstractforDetection of Terminal Mismatches on DNA Duplexes in Homogeneous Assays or with Immobilized Probes | Full Text | References | PDF (102.9 KB)
  • 42 Views
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