OncoTargets and Therapy, Volume 8, Issue (2015)

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OncoTargets and Therapy, Volume 8, Issue (2015)

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Review

Review Article
An update on PARP inhibitors for the treatment of cancer
Sarah Benafif & Marcia Hall
Pages: 519-528
Published online: 26 Feb 2015
AbstractforAn update on PARP inhibitors for the treatment of cancer | Full Text | References | PDF (605.6 KB)
  • 196 Views
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Open Access
Review Article
Critical appraisal of the role of ruxolitinib in myeloproliferative neoplasm-associated myelofibrosis
Giovanni Barosi, Vittorio Rosti & Robert Peter Gale
Pages: 1091-1102
Published online: 18 May 2015
AbstractforCritical appraisal of the role of ruxolitinib in myeloproliferative neoplasm-associated myelofibrosis | Full Text | References | PDF (327.1 KB)
  • 68 Views
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Open Access
Review Article
BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies
Francesco Spagnolo, Paola Ghiorzo, Laura Orgiano, Lorenza Pastorino, Virginia Picasso, Elena Tornari, Vincenzo Ottaviano & Paola Queirolo
Pages: 157-168
Published online: 16 Jan 2015
AbstractforBRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies | Full Text | References | PDF (313 KB)
  • 332 Views
  • 114 CrossRef citations
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Open Access
Review Article
Radium-223 for the treatment of castration-resistant prostate cancer
Joelle El-Amm & Jeanny B Aragon-Ching
Pages: 1103-1109
Published online: 18 May 2015
AbstractforRadium-223 for the treatment of castration-resistant prostate cancer | Full Text | References | PDF (197.3 KB)
  • 72 Views
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Open Access
Review Article
Extracellular matrix as target for antitumor therapy
Revekka Harisi & Andras Jeney
Pages: 1387-1398
Published online: 09 Jun 2015
AbstractforExtracellular matrix as target for antitumor therapy | Full Text | References | PDF (539.1 KB)
  • 120 Views
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Open Access
Review Article
Chronic neutrophilic leukemia: a clinical perspective
Juliane Menezes & Juan Cruz Cigudosa
Pages: 2383-2390
Published online: 01 Sep 2015
AbstractforChronic neutrophilic leukemia: a clinical perspective | Full Text | References | PDF (768.3 KB)
  • 89 Views
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Open Access
Review Article
Clinical applications of PD-1-based therapy: a focus on pembrolizumab (MK-3475) in the management of melanoma and other tumor types
Tara C Gangadhar & April KS Salama
Pages: 929-937
Published online: 22 Apr 2015
AbstractforClinical applications of PD-1-based therapy: a focus on pembrolizumab (MK-3475) in the management of melanoma and other tumor types | Full Text | References | PDF (867.3 KB)
  • 79 Views
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Open Access
Review Article
Profile of nimotuzumab in the treatment of high-grade glioma
Qun-ying Yang, Cheng-cheng Guo & Zhong-ping Chen
Pages: 819-825
Published online: 13 Apr 2015
AbstractforProfile of nimotuzumab in the treatment of high-grade glioma | Full Text | References | PDF (941.7 KB)
  • 120 Views
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Open Access
Review Article
Volasertib for AML: clinical use and patient consideration
Zhonglin Hao & Vamsi Kota
Pages: 1761-1771
Published online: 17 Jul 2015
AbstractforVolasertib for AML: clinical use and patient consideration | Full Text | References | PDF (811.9 KB)
  • 53 Views
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Open Access
Review Article
The utility of bexarotene in mycosis fungoides and Sézary syndrome
Manisha R Panchal & Julia J Scarisbrick
Pages: 367-373
Published online: 03 Feb 2015
AbstractforThe utility of bexarotene in mycosis fungoides and Sézary syndrome | Full Text | References | PDF (204.4 KB)
  • 111 Views
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Open Access
Review Article
Nivolumab in the treatment of malignant melanoma: review of the literature
Emi Mashima, Akiha Inoue, Yumiko Sakuragi, Takashi Yamaguchi, Natsuko Sasaki, Yoko Hara, Daisuke Omoto, Shun Ohmori, Sanehito Haruyama, Yu Sawada, Manabu Yoshioka, Daisuke Nishio & Motonobu Nakamura
Pages: 2045-2051
Published online: 06 Aug 2015
AbstractforNivolumab in the treatment of malignant melanoma: review of the literature | Full Text | References | PDF (290.5 KB)
  • 139 Views
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Open Access

Original Research

Article
NVP-BEZ235 overcomes gefitinib-acquired resistance by down-regulating PI3K/AKT/mTOR phosphorylation
Zhihua Sun, Qiuhui Li, Sheng Zhang, Jing Chen, Lili Huang, Jinghua Ren, Yu Chang, Yichen Liang & Gang Wu
Pages: 269-277
Published online: 29 Jan 2015
AbstractforNVP-BEZ235 overcomes gefitinib-acquired resistance by down-regulating PI3K/AKT/mTOR phosphorylation | Full Text | References | PDF (2.5 MB)
  • 51 Views
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Open Access
Article
Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells
Lan Yu, Xiaoli Wang, Da Zhu, Wencheng Ding, Liming Wang, Changlin Zhang, Xiaohui Jiang, Hui Shen, Shujie Liao, Ding Ma, Zheng Hu & Hui Wang
Pages: 37-44
Published online: 28 Nov 2022
AbstractforDisruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells | PDF (2 MB)
  • 55 Views
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Open Access

Review

Review Article
Targeted therapies for renal cell carcinoma in Chinese patients: focus on everolimus
Xiaojie Tan, Yan Liu, Jianguo Hou & Guangwen Cao
Pages: 313-321
Published online: 29 Jan 2015
AbstractforTargeted therapies for renal cell carcinoma in Chinese patients: focus on everolimus | Full Text | References | PDF (253.9 KB)
  • 61 Views
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Open Access
Review Article
Personalized treatment strategies for non-small-cell lung cancer in Chinese patients: the role of crizotinib
Fei-Yu Niu & Yi-Long Wu
Pages: 999-1007
Published online: 02 May 2015
AbstractforPersonalized treatment strategies for non-small-cell lung cancer in Chinese patients: the role of crizotinib | Full Text | References | PDF (336.9 KB)
  • 57 Views
  • 8 CrossRef citations
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Open Access
Review Article
Clinical utility and patient consideration in the use of lenalidomide for multiple myeloma in Chinese patients
Jing Wang, Hongfeng Guo & Xin Zhou
Pages: 1277-1284
Published online: 02 Jun 2015
AbstractforClinical utility and patient consideration in the use of lenalidomide for multiple myeloma in Chinese patients | Full Text | References | PDF (282.7 KB)
  • 51 Views
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Open Access

Original Research

Article
Lung cancer drug therapy in Hungary – 3-year experience
Judit Moldvay, György Rokszin, Zsolt Abonyi-Tóth, Lajos Katona, Katalin Fábián & Gábor Kovács
Pages: 1031-1038
Published online: 11 May 2015
AbstractforLung cancer drug therapy in Hungary – 3-year experience | Full Text | References | PDF (711.5 KB)
  • 64 Views
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Open Access

Review

Review Article
Ganetespib: research and clinical development
Komal Jhaveri & Shanu Modi
Pages: 1849-1858
Published online: 24 Jul 2015
AbstractforGanetespib: research and clinical development | Full Text | References | PDF (261.4 KB)
  • 134 Views
  • 24 CrossRef citations
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Open Access

Methodology

Article
Using an innovative multiple regression procedure in a cancer population (Part 1): detecting and probing relationships of common interacting symptoms (pain, fatigue/weakness, sleep problems) as a strategy to discover influential symptom pairs and clusters
Richard B Francoeur
Pages: 45-56
Published online: 22 Dec 2014
AbstractforUsing an innovative multiple regression procedure in a cancer population (Part 1): detecting and probing relationships of common interacting symptoms (pain, fatigue/weakness, sleep problems) as a strategy to discover influential symptom pairs and clusters | Full Text | References | PDF (297 KB)
  • 70 Views
  • 2 CrossRef citations
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Open Access

Review

Review Article
Novel targeted therapies for resistant ALK-rearranged non-small-cell lung cancer: ceritinib and beyond
Zeyad Kanaan, Goetz H Kloecker, Ajit Paintal & Cesar A Perez
Pages: 885-892
Published online: 20 Apr 2015
AbstractforNovel targeted therapies for resistant ALK-rearranged non-small-cell lung cancer: ceritinib and beyond | Full Text | References | PDF (445.7 KB)
  • 52 Views
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Open Access
Review Article
Triple-negative breast cancer: new perspectives for targeted therapies
Federica Tomao, Anselmo Papa, Eleonora Zaccarelli, Luigi Rossi, Davide Caruso, Marina Minozzi, Patrizia Vici, Luigi Frati & Silverio Tomao
Pages: 177-193
Published online: 16 Jan 2015
AbstractforTriple-negative breast cancer: new perspectives for targeted therapies | Full Text | References | PDF (353.2 KB)
  • 291 Views
  • 100 CrossRef citations
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Open Access

Original Research

Article
The role of Nanog expression in tamoxifen-resistant breast cancer cells
Khalid Arif, Issam Hussain, Carol Rea & Mohamed El-Sheemy
Pages: 1327-1334
Published online: 03 Jun 2015
AbstractforThe role of Nanog expression in tamoxifen-resistant breast cancer cells | Full Text | References | PDF (557.9 KB)
  • 111 Views
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Open Access

Case Series

Breast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature
Asumi Iesato, Takaaki Oba, Mayu Ono, Toru Hanamura, Takayuki Watanabe, Tokiko Ito, Toshiharu Kanai, Kazuma Maeno, Katsuhiko Ishizaka, Hiroyuki Kitabatake, Daisuke Takeuchi, Akira Suzuki, Jun Nakayama & Ken-ichi Ito
Pages: 91-97
Published online: 29 Dec 2014
AbstractforBreast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature | Full Text | References | PDF (1.5 MB)
  • 70 Views
  • 4 CrossRef citations
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Open Access

Original Research

Article
Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines
Ingrid Fumagalli, Delphine Dugue, Jean Emmanuel Bibault, Céline Clémenson, Marie Catherine Vozenin, Michele Mondini & Eric Deutsch
Pages: 335-345
Published online: 02 Feb 2015
AbstractforCytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines | Full Text | References | PDF (511.3 KB)
  • 52 Views
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Open Access

Case Report

Case Report
Use of allogeneic platelet gel in the management of chemotherapy extravasation injuries: a case report
Gaetano Di Costanzo, Giovanna Loquercio, Gianpaolo Marcacci, Vincenzo Iervolino, Stefano Mori, Arnolfo Petruzziello, Pasquale Barra & Carmela Cacciapuoti
Pages: 401-404
Published online: 09 Feb 2015
AbstractforUse of allogeneic platelet gel in the management of chemotherapy extravasation injuries: a case report | Full Text | References | PDF (953.4 KB)
  • 60 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Ethanol extracts of Cinnamomum kanehirai Hayata leaves induce apoptosis in human hepatoma cell through caspase-3 cascade
Yu-Kuo Liu, Kuan-Hsing Chen, Yann-Lii Leu, Tzong-Der Way, Ling-Wei Wang, Yu-Jen Chen & Yu-Ming Liu
Pages: 99-109
Published online: 31 Dec 2014
AbstractforEthanol extracts of Cinnamomum kanehirai Hayata leaves induce apoptosis in human hepatoma cell through caspase-3 cascade | Full Text | References | PDF (2.9 MB)
  • 107 Views
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Open Access

Review

Review Article
Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia
Brian T Hill & Matt Kalaycio
Pages: 2391-2397
Published online: 31 Aug 2015
AbstractforProfile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia | Full Text | References | PDF (773.9 KB)
  • 46 Views
  • 1 CrossRef citations
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Open Access

Case Report

Case Report
The imaging features of metanephric adenoma: a case report and review of literature
Yu-Chuan Hu, Lang Wu, Lin-Feng Yan, Wei Zhang & Guang-Bin Cui
Pages: 445-449
Published online: 13 Feb 2015
AbstractforThe imaging features of metanephric adenoma: a case report and review of literature | Full Text | References | PDF (1.3 MB)
  • 46 Views
  • 3 CrossRef citations
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Open Access

Methodology

Article
Using an innovative multiple regression procedure in a cancer population (Part II): fever, depressive affect, and mobility problems clarify an influential symptom pair (pain–fatigue/weakness) and cluster (pain–fatigue/weakness–sleep problems)
Richard B Francoeur
Pages: 57-72
Published online: 22 Dec 2014
AbstractforUsing an innovative multiple regression procedure in a cancer population (Part II): fever, depressive affect, and mobility problems clarify an influential symptom pair (pain–fatigue/weakness) and cluster (pain–fatigue/weakness–sleep problems) | Full Text | References | PDF (471.8 KB)
  • 77 Views
  • 1 CrossRef citations
  • 0Altmetric
Open Access

Case Report

Case Report
Fertility sparing surgery in young women affected by endometrial stromal sarcoma: an oncologic dilemma or a reliable option? review of literature starting from a peculiar case
Marco Noventa, Salvatore Gizzo, Lorena Conte, Angela Dalla Toffola, Pietro Litta & Carlo Saccardi
Pages: 29-35
Published online: 18 Dec 2014
AbstractforFertility sparing surgery in young women affected by endometrial stromal sarcoma: an oncologic dilemma or a reliable option? review of literature starting from a peculiar case | Full Text | References | PDF (3.7 MB)
  • 81 Views
  • 3 CrossRef citations
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Open Access

Review

Review Article
Profile of veliparib and its potential in the treatment of solid tumors
Lars M Wagner
Pages: 1931-1939
Published online: 29 Jul 2015
AbstractforProfile of veliparib and its potential in the treatment of solid tumors | Full Text | References | PDF (296.1 KB)
  • 210 Views
  • 62 CrossRef citations
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Open Access

Original Research

Article
Prolonged radiation time and low nadir hemoglobin during postoperative concurrent chemoradiotherapy are both poor prognostic factors with synergistic effect on locally advanced head and neck cancer patients
Nai-Wen Su, Chung-Ji Liu, Yi-Shing Leu, Jehn-Chuan Lee, Yu-Jen Chen & Yi-Fang Chang
Pages: 251-258
Published online: 28 Jan 2015
AbstractforProlonged radiation time and low nadir hemoglobin during postoperative concurrent chemoradiotherapy are both poor prognostic factors with synergistic effect on locally advanced head and neck cancer patients | Full Text | References | PDF (564.3 KB)
  • 48 Views
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Open Access

Review

Review Article
Current and emerging treatment options for hairy cell leukemia
Montserrat López-Rubio & Jose Antonio Garcia-Marco
Pages: 2147-2156
Published online: 19 Aug 2015
AbstractforCurrent and emerging treatment options for hairy cell leukemia | Full Text | References | PDF (391 KB)
  • 63 Views
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Open Access
Review Article
Profile of blinatumomab and its potential in the treatment of relapsed/refractory acute lymphoblastic leukemia
Josep-Maria Ribera, Albert Ferrer, Jordi Ribera & Eulàlia Genescà
Pages: 1567-1574
Published online: 24 Jun 2015
AbstractforProfile of blinatumomab and its potential in the treatment of relapsed/refractory acute lymphoblastic leukemia | Full Text | References | PDF (223.4 KB)
  • 105 Views
  • 34 CrossRef citations
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Open Access

Original Research

Article
Efficacy of sorafenib in advanced differentiated and medullary thyroid cancer: experience in a Turkish population
Mustafa Benekli, Suayib Yalcin, Metin Ozkan, Emin Tamer Elkiran, Alper Sevinc, Devrim Cabuk, Hasan Senol Coskun, Berna Oksuzoglu, Banu Bayar, Akif Akbulat, Ahmet Ozet & On behalf of Turkish Thyroid Cancer Study Group
Pages: 1-5
Published online: 15 Dec 2014
AbstractforEfficacy of sorafenib in advanced differentiated and medullary thyroid cancer: experience in a Turkish population | Full Text | References | PDF (559.9 KB)
  • 48 Views
  • 12 CrossRef citations
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Open Access
Article
Tyrphostin AG1296, a platelet-derived growth factor receptor inhibitor, induces apoptosis, and reduces viability and migration of PLX4032-resistant melanoma cells
Yanling Li, Yuping Li, Qiang Liu & Aixue Wang
Pages: 1043-1051
Published online: 14 May 2015
AbstractforTyrphostin AG1296, a platelet-derived growth factor receptor inhibitor, induces apoptosis, and reduces viability and migration of PLX4032-resistant melanoma cells | Full Text | References | PDF (1.8 MB)
  • 73 Views
  • 9 CrossRef citations
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Open Access
Article
Decreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma
Cristiana Tanase, Radu Albulescu, Elena Codrici, Bogdan Calenic, Ionela Daniela Popescu, Simona Mihai, Laura Necula, Maria Linda Cruceru & Mihail Eugen Hinescu
Pages: 81-90
Published online: 22 Dec 2014
AbstractforDecreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma | Full Text | References | PDF (2.4 MB)
  • 56 Views
  • 15 CrossRef citations
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Open Access
Article
Assessment and prognostic analysis of EGFR, HER2, and HER3 protein expression in surgically resected gastric adenocarcinomas
Daoqiang Tang, Charles YJ Liu, Danping Shen, Shuqiong Fan, Xinying Su, Peng Ye, Paul R Gavine & Xiaolu Yin
Pages: 7-14
Published online: 16 Dec 2014
AbstractforAssessment and prognostic analysis of EGFR, HER2, and HER3 protein expression in surgically resected gastric adenocarcinomas | Full Text | References | PDF (4.8 MB)
  • 89 Views
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Open Access

Case Report

Case Report
A clinical and radiological objective tumor response with somatostatin analogs (SSA) in well-differentiated neuroendocrine metastatic tumor of the ileum: a case report
Chiara De Divitiis, Claudia von Arx, Roberto Carbone, Fabiana Tatangelo, Elena Di Girolamo, Giovanni Maria Romano, Alessandro Ottaiano, Elisabetta de Lutio di Castelguidone, Rosario Vincenzo Iaffaioli, Salvatore Tafuto & On behalf of the European Neuroendocrine Tumor Society (ENETS) Center of Excellence Multidisciplinary Group for Neuroendocrine Tumors in Naples (Italy)
Pages: 669-675
Published online: 31 Mar 2015
AbstractforA clinical and radiological objective tumor response with somatostatin analogs (SSA) in well-differentiated neuroendocrine metastatic tumor of the ileum: a case report | Full Text | References | PDF (3.1 MB)
  • 56 Views
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Open Access

Original Research

Article
Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002
Xinyi Cai, Kun Yu, Lijuan Zhang, Yunfeng Li, Qiang Li, Zhibin Yang, Tao Shen, Lincan Duan, Wei Xiong & Weiya Wang
Pages: 877-883
Published online: 17 Apr 2015
AbstractforSynergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002 | Full Text | References | PDF (477.2 KB)
  • 71 Views
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Open Access
Article
Lumbosacral plexus delineation, dose distribution, and its correlation with radiation-induced lumbosacral plexopathy in cervical cancer patients
Mutahir Tunio, Mushabbab Al Asiri, Yasser Bayoumi, Ali Abdullah O Balbaid, Majid AlHameed, Stanciu Laura Gabriela & Ahmad Amir O Ali
Pages: 21-27
Published online: 23 Dec 2014
AbstractforLumbosacral plexus delineation, dose distribution, and its correlation with radiation-induced lumbosacral plexopathy in cervical cancer patients | Full Text | References | PDF (2 MB)
  • 123 Views
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Open Access
Article
Pilot study investigating the prognostic significance of thymidine phosphorylase expression in patients with metastatic breast cancer: a single institution retrospective analysis
Anna Lisa Tedeschi, Zohreh Eslami, Evgenia Garoufalis, Ramy R Saleh, Atilla Omeroglu, Gulbeyaz Altinel, Maria Ait-Tihyaty, Bertrand Jean-Claude & Catalin Mihalcioiu
Pages: 911-919
Published online: 21 Apr 2015
AbstractforPilot study investigating the prognostic significance of thymidine phosphorylase expression in patients with metastatic breast cancer: a single institution retrospective analysis | Full Text | References | PDF (2.1 MB)
  • 50 Views
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Open Access
Article
Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines
David CL Lam, Susan Y Luo, Wen Deng, Johnny SH Kwan, Jaime Rodriguez-Canales, Annie LM Cheung, Grace HW Cheng, Chi-Ho Lin, Ignacio I Wistuba, Pak C Sham, Thomas SK Wan & Sai-Wah Tsao
Pages: 195-209
Published online: 16 Jan 2015
AbstractforOncogenic mutation profiling in new lung cancer and mesothelioma cell lines | Full Text | References | PDF (4.9 MB)
  • 64 Views
  • 3 CrossRef citations
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Open Access

Case Series

Astroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas?
Marta Mellai, Angela Piazzi, Cristina Casalone, Silvia Grifoni, Antonio Melcarne, Laura Annovazzi, Paola Cassoni, Tetyana Denysenko, Maria Consuelo Valentini, Angelina Cistaro & Davide Schiffer
Pages: 451-460
Published online: 19 Feb 2015
AbstractforAstroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas? | Full Text | References | PDF (4.6 MB)
  • 60 Views
  • 13 CrossRef citations
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Open Access

Original Research

Article
Tumor deposit is a poor prognostic indicator in patients who underwent simultaneous resection for synchronous colorectal liver metastases
Qi Lin, Ye Wei, Li Ren, Yunshi Zhong, Chunzhi Qin, Peng Zheng, Pingping Xu, Dexiang Zhu, Meiling Ji & Jianmin Xu
Pages: 233-240
Published online: 22 Jan 2015
AbstractforTumor deposit is a poor prognostic indicator in patients who underwent simultaneous resection for synchronous colorectal liver metastases | Full Text | References | PDF (946.7 KB)
  • 48 Views
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Open Access

Review

Review Article
Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options
Alok T Saini & Brett A Miles
Pages: 2157-2167
Published online: 19 Aug 2015
AbstractforMerkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options | Full Text | References | PDF (1.3 MB)
  • 97 Views
  • 4 CrossRef citations
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Open Access

Original Research

Article
miR-32 functions as a tumor suppressor and directly targets SOX9 in human non-small cell lung cancer
Dan Zhu, Hui Chen, Xiguang Yang, Weisong Chen, Linying Wang, Jilin Xu & Long Yu
Pages: 1773-1783
Published online: 28 Nov 2022
AbstractformiR-32 functions as a tumor suppressor and directly targets SOX9 in human non-small cell lung cancer | PDF (2.3 MB)
  • 38 Views
  • 10 CrossRef citations
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Open Access

Review

Review Article
Advances in the targeted therapy of liposarcoma
Zhonghai Guan, Xiongfei Yu, Haohao Wang, Haiyong Wang, Jing Zhang, Guangliang Li, Jiang Cao & Lisong Teng
Pages: 125-136
Published online: 05 Jan 2015
AbstractforAdvances in the targeted therapy of liposarcoma | Full Text | References | PDF (318.5 KB)
  • 134 Views
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Open Access

Original Research

Article
The association between the migration inhibitory factor −173G/C polymorphism and cancer risk: a meta-analysis
Xiao Zhang, Wenhao Weng, Wen Xu, Yulan Wang, Wenjun Yu, Xun Tang, Lifang Ma, Qiuhui Pan, Jiayi Wang & Fenyong Sun
Pages: 601-613
Published online: 10 Mar 2015
AbstractforThe association between the migration inhibitory factor −173G/C polymorphism and cancer risk: a meta-analysis | Full Text | References | PDF (1,002.5 KB)
  • 55 Views
  • 4 CrossRef citations
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Open Access

Review

Review Article
New developments in the management of advanced melanoma – role of pembrolizumab
Giuseppina Improta, Isabella Leone, Marco Donia, Stefania Gieri, Giuseppe Pelosi & Filippo Fraggetta
Pages: 2535-2543
Published online: 14 Sep 2015
AbstractforNew developments in the management of advanced melanoma – role of pembrolizumab | Full Text | References | PDF (1.3 MB)
  • 135 Views
  • 13 CrossRef citations
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Open Access

Original Research

Article
The landscape of alternative splicing in cervical squamous cell carcinoma
Peng Guo, Dan Wang, Jun Wu, Junjun Yang, Tong Ren, Baoli Zhu & Yang Xiang
Pages: 73-79
Published online: 22 Dec 2014
AbstractforThe landscape of alternative splicing in cervical squamous cell carcinoma | Full Text | References | PDF (648.7 KB)
  • 153 Views
  • 7 CrossRef citations
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Open Access

Review

Review Article
Trametinib: a MEK inhibitor for management of metastatic melanoma
Iwona Lugowska, Hanna Koseła-Paterczyk, Katarzyna Kozak & Piotr Rutkowski
Pages: 2251-2259
Published online: 25 Aug 2015
AbstractforTrametinib: a MEK inhibitor for management of metastatic melanoma | Full Text | References | PDF (348.4 KB)
  • 717 Views
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Open Access
Review Article
Profile of bevacizumab and its potential in the treatment of cervical cancer
Christine M Fisher & Tracey E Schefter
Pages: 3425-3431
Published online: 19 Nov 2015
AbstractforProfile of bevacizumab and its potential in the treatment of cervical cancer | Full Text | References | PDF (190.2 KB)
  • 77 Views
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Open Access

Original Research

Article
Early enteral and parenteral nutritional support after hepatectomy in patients with hepatic carcinoma: a systematic review and meta-analysis
Lin-Ben Gao, He Tian, Xing-Guang Wang, Xiao-Fei Yu, Yan Guan, Ming-Lu Chen & Jian Zhang
Pages: 623-631
Published online: 10 Mar 2015
AbstractforEarly enteral and parenteral nutritional support after hepatectomy in patients with hepatic carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (824.9 KB)
  • 82 Views
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Open Access
Article
High mobility group box-1 and its clinical value in breast cancer
Shanping Sun, Wei Zhang, Zhaoqing Cui, Qi Chen, Panpan Xie, Changxin Zhou, Baoguo Liu, Xiangeng Peng & Yang Zhang
Pages: 413-419
Published online: 12 Feb 2015
AbstractforHigh mobility group box-1 and its clinical value in breast cancer | Full Text | References | PDF (769.6 KB)
  • 97 Views
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Open Access
Article
Assessment of selected cytokines, proteins, and growth factors in the peritoneal fluid of patients with ovarian cancer and benign gynecological conditions
Anita Monika Chudecka-Głaz, Aneta Alicja Cymbaluk-Płoska, Janusz Leszek Menkiszak, Ewa Pius-Sadowska, Bogusław Bronisław Machaliński, Agnieszka Sompolska-Rzechuła & Izabella Anna Rzepka-Górska
Pages: 471-485
Published online: 23 Feb 2015
AbstractforAssessment of selected cytokines, proteins, and growth factors in the peritoneal fluid of patients with ovarian cancer and benign gynecological conditions | Full Text | References | PDF (674.4 KB)
  • 87 Views
  • 17 CrossRef citations
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Open Access
Article
Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787
Aulma R Parker, Pavankumar N Petluru, Vicki L Nienaber, Min Zhao, Philippe Y Ayala, John Badger, Barbara Chie-Leon, Vandana Sridhar, Cheyenne Logan, Harry Kochat & Frederick H Hausheer
Pages: 375-383
Published online: 04 Feb 2015
AbstractforNovel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787 | Full Text | References | PDF (1.3 MB)
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Article
Gefitinib upregulates death receptor 5 expression to mediate rmhTRAIL-induced apoptosis in Gefitinib-sensitive NSCLC cell line
Dong Yan, Yang Ge, Haiteng Deng, Wenming Chen & Guangyu An
Pages: 1603-1610
Published online: 03 Jul 2015
AbstractforGefitinib upregulates death receptor 5 expression to mediate rmhTRAIL-induced apoptosis in Gefitinib-sensitive NSCLC cell line | Full Text | References | PDF (1.6 MB)
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Article
Low preoperative lymphocyte to monocyte ratio predicts poor cancer-specific survival in patients with esophageal squamous cell carcinoma
Ying Huang & Ji-Feng Feng
Pages: 137-145
Published online: 08 Jan 2015
AbstractforLow preoperative lymphocyte to monocyte ratio predicts poor cancer-specific survival in patients with esophageal squamous cell carcinoma | Full Text | References | PDF (3.3 MB)
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Review

Review Article
Computed tomography versus magnetic resonance imaging for diagnosing cervical lymph node metastasis of head and neck cancer: a systematic review and meta-analysis
J Sun, B Li, CJ Li, Y Li, F Su, QH Gao, FL Wu, T Yu, L Wu & LJ Li
Pages: 1291-1313
Published online: 08 Jun 2015
AbstractforComputed tomography versus magnetic resonance imaging for diagnosing cervical lymph node metastasis of head and neck cancer: a systematic review and meta-analysis | Full Text | References | PDF (2.3 MB)
  • 227 Views
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Original Research

Article
Neoadjuvant hormone therapy following treatment with robotic-assisted radical prostatectomy achieved favorable in high-risk prostate cancer
Cheng-Pang Hou, Wei-Chang Lee, Yu-Hsiang Lin, Shao-Ming Chen, Chien-Lun Chen, Phei-Lang Chang, Horng-Heng Juang & Ke-Hung Tsui
Pages: 15-19
Published online: 17 Dec 2014
AbstractforNeoadjuvant hormone therapy following treatment with robotic-assisted radical prostatectomy achieved favorable in high-risk prostate cancer | Full Text | References | PDF (267 KB)
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Article
Impact on growth and invasion of gastric cancer cell lines by silencing NEDD9
Sisen Zhang, Lihua Wu, Qing Liu, Kuisheng Chen & Xiefu Zhang
Pages: 223-231
Published online: 20 Jan 2015
AbstractforImpact on growth and invasion of gastric cancer cell lines by silencing NEDD9 | Full Text | References | PDF (1.2 MB)
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Case Report

Case Report
Efficacy of nab-paclitaxel plus trastuzumab in a long-surviving heavily pretreated HER2-positive breast cancer patient with brain metastases
Giuseppina Rosaria Rita Ricciardi, Alessandro Russo, Tindara Franchina, Giuseppa Ferraro & Vincenzo Adamo
Pages: 289-294
Published online: 02 Feb 2015
AbstractforEfficacy of nab-paclitaxel plus trastuzumab in a long-surviving heavily pretreated HER2-positive breast cancer patient with brain metastases | Full Text | References | PDF (1.3 MB)
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Original Research

Article
HMGA2 is associated with epithelial–mesenchymal transition and can predict poor prognosis in nasopharyngeal carcinoma
You-You Xia, Li Yin, Hao Tian, Wen-Jie Guo, Ning Jiang, Xue-Song Jiang, Jing Wu, Meng Chen, Jian-Zhong Wu & Xia He
Pages: 169-176
Published online: 17 Jan 2015
AbstractforHMGA2 is associated with epithelial–mesenchymal transition and can predict poor prognosis in nasopharyngeal carcinoma | Full Text | References | PDF (3.1 MB)
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Article
The impact of IGF-1R expression on the outcomes of patients with breast cancer: a meta-analysis
Shunchao Yan, Xin Jiao, Kai Li, Wusheng Li & Huawei Zou
Pages: 279-287
Published online: 29 Jan 2015
AbstractforThe impact of IGF-1R expression on the outcomes of patients with breast cancer: a meta-analysis | Full Text | References | PDF (641 KB)
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Article
Clinical and epidemiological study of EGFR mutations and EML4-ALK fusion genes among Indian patients with adenocarcinoma of the lung
DC Doval, K Prabhash, S Patil, H Chaturvedi, C Goswami, AK Vaid, S Desai, S Dutt, VH Veldore, N Jambhekar, A Mehta, D Hazarika, S Azam, S Gawande & S Gupta
Pages: 117-123
Published online: 05 Jan 2015
AbstractforClinical and epidemiological study of EGFR mutations and EML4-ALK fusion genes among Indian patients with adenocarcinoma of the lung | Full Text | References | PDF (221.7 KB)
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Article
Prognostic role of apoptosis-related gene functional variants in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy
Kai-Yi Tao, Xian-Xing Li, Wei-Zhen Xu, Yin Wang, Shuang-Mei Zhu, Hua-Xia Xie, Wen-Hua Luo, Yan-Jun Xu & Xiao-Ling Xu
Pages: 147-155
Published online: 14 Jan 2015
AbstractforPrognostic role of apoptosis-related gene functional variants in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy | Full Text | References | PDF (1.6 MB)
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Article
Use of transient elastography to predict de novo recurrence after radiofrequency ablation for hepatocellular carcinoma
Sang Hoon Lee, Seung Up Kim, Jeong Won Jang, Si Hyun Bae, Sanghun Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn & Kwang–Hyub Han
Pages: 347-356
Published online: 02 Feb 2015
AbstractforUse of transient elastography to predict de novo recurrence after radiofrequency ablation for hepatocellular carcinoma | Full Text | References | PDF (423.3 KB)
  • 61 Views
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Article
Adjuvant treatment in patients at high risk of recurrence of thymoma: efficacy and safety of a three-dimensional conformal radiation therapy regimen
Francesco Perri, Salvatore Pisconti, Manuel Conson, Roberto Pacelli, Giuseppina Della Vittoria Scarpati, Antonio Gnoni, Carmine D’Aniello, Carla Cavaliere, Antonella Licchetta, Laura Cella, Mario Giuliano, Concetta Schiavone, Sara Falivene, Giuseppe Di Lorenzo, Carlo Buonerba, Vincenzo Ravo & Paolo Muto
Pages: 1345-1349
Published online: 08 Jun 2015
AbstractforAdjuvant treatment in patients at high risk of recurrence of thymoma: efficacy and safety of a three-dimensional conformal radiation therapy regimen | Full Text | References | PDF (342.6 KB)
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Case Series

Combination of afatinib with cetuximab in patients with EGFR-mutant non-small-cell lung cancer resistant to EGFR inhibitors
Jéssica Ribeiro Gomes & Marcelo Rocha S Cruz
Pages: 1137-1142
Published online: 19 May 2015
AbstractforCombination of afatinib with cetuximab in patients with EGFR-mutant non-small-cell lung cancer resistant to EGFR inhibitors | Full Text | References | PDF (217.7 KB)
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Original Research

Article
Anticoagulant therapy for venous thromboembolism detected by Doppler ultrasound in patients with metastatic colorectal cancer receiving bevacizumab
Mitsukuni Suenaga, Nobuyuki Mizunuma, Eiji Shinozaki, Satoshi Matsusaka, Masato Ozaka, Mariko Ogura, Keisho Chin & Toshiharu Yamaguchi
Pages: 243-249
Published online: 27 Jan 2015
AbstractforAnticoagulant therapy for venous thromboembolism detected by Doppler ultrasound in patients with metastatic colorectal cancer receiving bevacizumab | Full Text | References | PDF (339.2 KB)
  • 51 Views
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Article
XPA A23G polymorphism and risk of digestive system cancers: a meta-analysis
Lei He, Tao Deng & Hesheng Luo
Pages: 385-394
Published online: 05 Feb 2015
AbstractforXPA A23G polymorphism and risk of digestive system cancers: a meta-analysis | Full Text | References | PDF (710.7 KB)
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Methodology

Article
The power of the age standardized incidence rate to discover the gene link between cancer diseases: development of a new epidemiological method to save money, time, and effort for genetic scientists
Ibrahim G Alghamdi, Issam I Hussain, Mohamed S Alghamdi & Mohammed A El-Sheemy
Pages: 677-687
Published online: 31 Mar 2015
AbstractforThe power of the age standardized incidence rate to discover the gene link between cancer diseases: development of a new epidemiological method to save money, time, and effort for genetic scientists | Full Text | References | PDF (2.3 MB)
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Original Research

Article
Meta-analysis of the association between APC promoter methylation and colorectal cancer
Zhenyu Ding, Tong Jiang, Ying Piao, Tao Han, Yaling Han & Xiaodong Xie
Pages: 211-222
Published online: 19 Jan 2015
AbstractforMeta-analysis of the association between APC promoter methylation and colorectal cancer | Full Text | References | PDF (1.4 MB)
  • 71 Views
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Article
RETRACTED: Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest
Rong Xie, Yichao Zhang, Chao Shen & Xiaoming Che
Pages: 1119-1127
Published online: 28 Nov 2022
AbstractforRETRACTED: Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest | PDF (1.6 MB)
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Review

Review Article
The role of miR-29b in cancer: regulation, function, and signaling
Bin Yan, Qiong Guo, Fa-jun Fu, Zhao Wang, Zhuo Yin, Yong-bao Wei & Jin-rui Yang
Pages: 539-548
Published online: 03 Mar 2015
AbstractforThe role of miR-29b in cancer: regulation, function, and signaling | Full Text | References | PDF (388.1 KB)
  • 237 Views
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Original Research

Article
Multimodality therapy is recommended for limited-stage combined small cell esophageal carcinoma
Huan-Huan Wang, Nicholas G Zaorsky, Mao-Bin Meng, Zhi-Qiang Wu, Xian-Liang Zeng, Bo Jiang, Chao Jiang, Lu-Jun Zhao, Zhi-Yong Yuan & Ping Wang
Pages: 437-444
Published online: 13 Feb 2015
AbstractforMultimodality therapy is recommended for limited-stage combined small cell esophageal carcinoma | Full Text | References | PDF (653.6 KB)
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Article
Tubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway
Geng Jia, Qiang Wang, Rong Wang, Danni Deng, Lian Xue, Naiyuan Shao, Yi Zhang, Xiwei Xia, Feng Zhi & Yilin Yang
Pages: 303-311
Published online: 30 Jan 2015
AbstractforTubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway | Full Text | References | PDF (2.1 MB)
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Article
Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth
Jie Li, Chao Zhang, Hongchuan Jiang & Jiao Cheng
Pages: 427-435
Published online: 13 Feb 2015
AbstractforAndrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth | Full Text | References | PDF (1.5 MB)
  • 106 Views
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Article
Apoptosis of HeLa cells induced by a new targeting photosensitizer-based PDT via a mitochondrial pathway and ER stress
Donghong Li, Lei Li, Pengxi Li, Yi Li & Xiangyun Chen
Pages: 703-711
Published online: 07 Apr 2015
AbstractforApoptosis of HeLa cells induced by a new targeting photosensitizer-based PDT via a mitochondrial pathway and ER stress | Full Text | References | PDF (2.6 MB)
  • 83 Views
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Article
Micro-ribonucleic acid 29b inhibits cell proliferation and invasion and enhances cell apoptosis and chemotherapy effects of cisplatin via targeting of DNMT3b and AKT3 in prostate cancer
Bin Yan, Qiong Guo, Xiao-xin Nan, Zhao Wang, Zhuo Yin, Lu Yi, Yong-bao Wei, Yun-liang Gao, Ke-qin Zhou & Jin-rui Yang
Pages: 557-565
Published online: 04 Mar 2015
AbstractforMicro-ribonucleic acid 29b inhibits cell proliferation and invasion and enhances cell apoptosis and chemotherapy effects of cisplatin via targeting of DNMT3b and AKT3 in prostate cancer | Full Text | References | PDF (1.2 MB)
  • 51 Views
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Article
Clinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies
Tingting Zhao, Chun Wang, Lili Shen, Dongying Gu, Zhi Xu, Xunlei Zhang, Yong Xu & Jinfei Chen
Pages: 649-659
Published online: 23 Mar 2015
AbstractforClinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies | Full Text | References | PDF (868.5 KB)
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Case Series

Lung cancer patients harboring epidermal growth factor receptor mutation among those infected by human immunodeficiency virus
Yusuke Okuma, Yukio Hosomi & Akifumi Imamura
Pages: 111-115
Published online: 31 Dec 2014
AbstractforLung cancer patients harboring epidermal growth factor receptor mutation among those infected by human immunodeficiency virus | Full Text | References | PDF (563.4 KB)
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Original Research

Article
Changes in sebum levels and the development of acneiform rash in patients with non–small cell lung cancer after treatment with EGFR inhibitors
Takeshi Nakahara, Yoichi Moroi, Koichi Takayama, Eriko Itoh, Makiko Kido-Nakahara, Yoichi Nakanishi & Masutaka Furue
Pages: 259-263
Published online: 28 Jan 2015
AbstractforChanges in sebum levels and the development of acneiform rash in patients with non–small cell lung cancer after treatment with EGFR inhibitors | Full Text | References | PDF (506.1 KB)
  • 57 Views
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Article
Accumulation of p53 is prognostic for aromatase inhibitor resistance in early-stage postmenopausal patients with ER-positive breast cancer
Xiao-qing Jia, Qi Hong, Jing-yi Cheng, Jian-wei Li, Yu-jie Wang, Miao Mo, Zhi-min Shao, Zhen-zhou Shen & Guang-yu Liu
Pages: 549-555
Published online: 03 Mar 2015
AbstractforAccumulation of p53 is prognostic for aromatase inhibitor resistance in early-stage postmenopausal patients with ER-positive breast cancer | Full Text | References | PDF (1.5 MB)
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Article
Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair
Hai Liu, Weifang Yang, Huaping Gao, Tingting Jiang, Bengxin Gu, Qinghua Dong, Wenhong Xu, Shixiu Wu & Xiaonan Sun
Pages: 509-518
Published online: 25 Feb 2015
AbstractforNimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair | Full Text | References | PDF (2.8 MB)
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Article
The clinical significances of the abnormal expressions of Piwil1 and Piwil2 in colonic adenoma and adenocarcinoma
Hai-Ling Wang, Bei-Bei Chen, Xin-Guang Cao, Jin Wang, Xiu-Feng Hu, Xiao-Qian Mu & Xiao-Bing Chen
Pages: 1259-1264
Published online: 27 May 2015
AbstractforThe clinical significances of the abnormal expressions of Piwil1 and Piwil2 in colonic adenoma and adenocarcinoma | Full Text | References | PDF (1.4 MB)
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Article
Development of a preliminary nomogram to predict progression of bone scan for castration-resistant prostate cancer
Guo-Wen Lin, Ding-Wei Ye, Hui-Xun Jia, Bo Dai, Hai-Liang Zhang, Yao Zhu, Guo-Hai Shi & Chun-Guang Ma
Pages: 713-719
Published online: 07 Apr 2015
AbstractforDevelopment of a preliminary nomogram to predict progression of bone scan for castration-resistant prostate cancer | Full Text | References | PDF (348.4 KB)
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Article
Prognostic significance of neutrophil-to- lymphocyte ratio in esophageal cancer: a meta-analysis
Xun Yang, Ying Huang, Ji-Feng Feng & Jin-Shi Liu
Pages: 789-794
Published online: 10 Apr 2015
AbstractforPrognostic significance of neutrophil-to- lymphocyte ratio in esophageal cancer: a meta-analysis | Full Text | References | PDF (698.7 KB)
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Article
Comparison between three oxaliplatin-based regimens with bevacizumab in patients with metastatic colorectal cancer
Yoshihito Ohhara, Mitsukuni Suenaga, Satoshi Matsusaka, Eiji Shinozaki, Nobuyuki Mizunuma & Toshiharu Yamaguchi
Pages: 529-537
Published online: 03 Mar 2015
AbstractforComparison between three oxaliplatin-based regimens with bevacizumab in patients with metastatic colorectal cancer | Full Text | References | PDF (668.7 KB)
  • 63 Views
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Article
Nimotuzumab enhances radiation sensitivity of NSCLC H292 cells in vitro by blocking epidermal growth factor receptor nuclear translocation and inhibiting radiation-induced DNA damage repair
Kai Teng, Yong Zhang, Xiaoyan Hu, Yihui Ding, Rui Gong & Li Liu
Pages: 809-818
Published online: 13 Apr 2015
AbstractforNimotuzumab enhances radiation sensitivity of NSCLC H292 cells in vitro by blocking epidermal growth factor receptor nuclear translocation and inhibiting radiation-induced DNA damage repair | Full Text | References | PDF (1.6 MB)
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Case Report

Case Report
Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature
Xiaoqin Liang, Yingmei Wang, Jinsong Zhang, Hong Cheng, Jinsui Wang, Yamei Dang, Haomin Li, Ru Zhou, Jing Zhang & Qing Qiao
Pages: 1143-1147
Published online: 19 May 2015
AbstractforAnaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature | Full Text | References | PDF (3.4 MB)
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Original Research

Article
Epothilones in epithelial ovarian, fallopian tube, or primary peritoneal cancer: a systematic review
Flora Zagouri, Theodoros N Sergentanis, Dimosthenis Chrysikos, Meletios-Athanassios Dimopoulos & Aristotle Bamias
Pages: 2187-2198
Published online: 20 Aug 2015
AbstractforEpothilones in epithelial ovarian, fallopian tube, or primary peritoneal cancer: a systematic review | Full Text | References | PDF (385.7 KB)
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Article
Roles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis
Meiling Lu, Jinghua Li, Zaili Luo, Shuai Zhang, Shaobo Xue, Kesheng Wang, Yan Shi, Cunzhen Zhang, Haiyang Chen & Zhong Li
Pages: 1543-1552
Published online: 22 Jun 2015
AbstractforRoles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis | Full Text | References | PDF (2.4 MB)
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Article
The combination of preoperative serum C-reactive protein and carcinoembryonic antigen is a useful prognostic factor in patients with esophageal squamous cell carcinoma: a combined ROC analysis
Ying Huang, Jin-Shi Liu & Ji-Feng Feng
Pages: 795-803
Published online: 10 Apr 2015
AbstractforThe combination of preoperative serum C-reactive protein and carcinoembryonic antigen is a useful prognostic factor in patients with esophageal squamous cell carcinoma: a combined ROC analysis | Full Text | References | PDF (2.1 MB)
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Review

Review Article
Epoetin beta for the treatment of chemotherapy-induced anemia: an update
Luca Galli, Clara Ricci & Colin Gerard Egan
Pages: 583-591
Published online: 05 Mar 2015
AbstractforEpoetin beta for the treatment of chemotherapy-induced anemia: an update | Full Text | References | PDF (769.6 KB)
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Original Research

Article
Targeting specificity of dendritic cells on breast cancer stem cells: in vitro and in vivo evaluations
Sinh Truong Nguyen, Huyen Lam Nguyen, Viet Quoc Pham, Giang Thuy Nguyen, Cuong Do-Thanh Tran, Ngoc Kim Phan & Phuc Van Pham
Pages: 323-334
Published online: 30 Jan 2015
AbstractforTargeting specificity of dendritic cells on breast cancer stem cells: in vitro and in vivo evaluations | Full Text | References | PDF (4.4 MB)
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Article
In vivo DNA damaging and apoptotic potential of silver nanoparticles in Swiss albino mice
Mohammed A Al Gurabi, Daoud Ali, Saad Alkahtani & Saud Alarifi
Pages: 295-302
Published online: 29 Jan 2015
AbstractforIn vivo DNA damaging and apoptotic potential of silver nanoparticles in Swiss albino mice | Full Text | References | PDF (2 MB)
  • 135 Views
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Article
RETRACTED ARTICLE: PP4R1 accelerates cell growth and proliferation in HepG2 hepatocellular carcinoma
Gang Wu, Zhenyu Ma, Jianmin Qian & Bin Liu
Pages: 2067-2074
Published online: 07 Aug 2015
AbstractforRETRACTED ARTICLE: PP4R1 accelerates cell growth and proliferation in HepG2 hepatocellular carcinoma | PDF (1.3 MB)
  • 51 Views
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Article
Elevated expression of NEDD9 is associated with metastatic activity in gastric cancer
Si-sen Zhang, Li-hua Wu, Qing Liu, Kui-sheng Chen & Xie-fu Zhang
Pages: 633-640
Published online: 10 Mar 2015
AbstractforElevated expression of NEDD9 is associated with metastatic activity in gastric cancer | Full Text | References | PDF (1.3 MB)
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Article
Relationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis
Zesheng Wu, Peng Jiang, Haider Zulqarnain, Hua Gao & Wenbin Zhang
Pages: 861-869
Published online: 16 Apr 2015
AbstractforRelationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis | Full Text | References | PDF (757.9 KB)
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Article
HGF and NRG1 protein expression are not poor prognostic markers in surgically resected lung adenocarcinoma
Bin Pan, Rui Wang, Yangle Huang, David Garfield, Jie Zhang & Haiquan Chen
Pages: 1185-1191
Published online: 25 May 2015
AbstractforHGF and NRG1 protein expression are not poor prognostic markers in surgically resected lung adenocarcinoma | Full Text | References | PDF (1.6 MB)
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Article
Predictive value of plasma D-dimer levels in patients with advanced non-small-cell lung cancer
Yuezhen Wang & Zhun Wang
Pages: 805-808
Published online: 13 Apr 2015
AbstractforPredictive value of plasma D-dimer levels in patients with advanced non-small-cell lung cancer | Full Text | References | PDF (331.2 KB)
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Case Report

Case Report
Primary malignant lymphoma of the uterus and broad ligament: a case report and review of literature
Runzhe Chen, Zhengping Yu, Hongming Zhang, Jiahua Ding & Baoan Chen
Pages: 265-268
Published online: 29 Jan 2015
AbstractforPrimary malignant lymphoma of the uterus and broad ligament: a case report and review of literature | Full Text | References | PDF (1.6 MB)
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Original Research

Article
MicroRNA-153 acts as a prognostic marker in gastric cancer and its role in cell migration and invasion
Zhengliang Zhang, Jiangli Sun, Zhenghai Bai, Haijun Li, Shicai He, Rui Chen & Xiangming Che
Pages: 357-364
Published online: 02 Feb 2015
AbstractforMicroRNA-153 acts as a prognostic marker in gastric cancer and its role in cell migration and invasion | Full Text | References | PDF (2.7 MB)
  • 70 Views
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Article
Expression of ARs in triple negative breast cancer tumors: a potential prognostic factor?
Aris Giannos, Martin Filipits, Flora Zagouri, Anita Brandstetter, Alexandra Tsigginou, Maria Sotiropoulou, Irene Papaspyrou, Theodoros N Sergentanis, Theodora Psaltopoulou, Alexandros Rodolakis, Aris Antsaklis, Meletios-Athanasios Dimopoulos & Constantine Dimitrakakis
Pages: 1843-1847
Published online: 23 Jul 2015
AbstractforExpression of ARs in triple negative breast cancer tumors: a potential prognostic factor? | Full Text | References | PDF (801.6 KB)
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Article
Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancer SSC-4 cells
Alexandra Iulia Irimie, Cornelia Braicu, Oana Zanoaga, Valentina Pileczki, Claudia Gherman, Ioana Berindan-Neagoe & Radu Septimiu Campian
Pages: 461-470
Published online: 20 Feb 2015
AbstractforEpigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancer SSC-4 cells | Full Text | References | PDF (2.4 MB)
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Article
Investigation of brain tumors using 18F-fluorobutyl ethacrynic amide and its metabolite with positron emission tomography
Ying-Cheng Huang, Ho-Lien Huang, Chun-Nan Yeh, Kun-Ju Lin & Chung-Shan Yu
Pages: 1877-1885
Published online: 24 Jul 2015
AbstractforInvestigation of brain tumors using 18F-fluorobutyl ethacrynic amide and its metabolite with positron emission tomography | Full Text | References | PDF (1.4 MB)
  • 40 Views
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Article
Upregulation of nucleostemin in colorectal cancer and its effects on cell malignancy
Bin Wei, Qiaoying Huang & Xiaogang Zhong
Pages: 1805-1814
Published online: 28 Nov 2022
AbstractforUpregulation of nucleostemin in colorectal cancer and its effects on cell malignancy | PDF (3 MB)
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Article
Hyperthermia combined with 5-fluorouracil promoted apoptosis and enhanced thermotolerance in human gastric cancer cell line SGC-7901
Tao Liu, Yan-Wei Ye, A-li Zhu, Zhen Yang, Yang Fu, Chong-Qing Wei, Qi Liu, Chun-Lin Zhao, Guo-Jun Wang & Xie-Fu Zhang
Pages: 1265-1270
Published online: 27 May 2015
AbstractforHyperthermia combined with 5-fluorouracil promoted apoptosis and enhanced thermotolerance in human gastric cancer cell line SGC-7901 | Full Text | References | PDF (392.6 KB)
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Review

Review Article
Prophylaxis and treatment of acute lymphoblastic leukemia relapse after allogeneic hematopoietic stem cell transplantation
Runzhe Chen, Jos L Campbell & Baoan Chen
Pages: 405-412
Published online: 10 Feb 2015
AbstractforProphylaxis and treatment of acute lymphoblastic leukemia relapse after allogeneic hematopoietic stem cell transplantation | Full Text | References | PDF (206.4 KB)
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Original Research

Article
Association between chemotactic chemokine ligand 5 -403G/A polymorphism and risk of human immunodeficiency virus-1 infection: a meta-analysis
Jianglong He, Xiaoquan Li, Jialin Tang, Tinli Jin, Qinghua Liao & Guoliang Hu
Pages: 727-734
Published online: 07 Apr 2015
AbstractforAssociation between chemotactic chemokine ligand 5 -403G/A polymorphism and risk of human immunodeficiency virus-1 infection: a meta-analysis | Full Text | References | PDF (778.8 KB)
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Article
Human papillomavirus 16 infection predicts poor outcome in patients with esophageal squamous cell carcinoma
Ruxing Xi, Xiaozhi Zhang, Xin Chen, Shupei Pan, Beina Hui, Li Zhang, Shenbo Fu, Xiaolong Li, Xuanwei Zhang, Tuotuo Gong, Jia Guo & Shaomin Che
Pages: 573-581
Published online: 05 Mar 2015
AbstractforHuman papillomavirus 16 infection predicts poor outcome in patients with esophageal squamous cell carcinoma | Full Text | References | PDF (1.6 MB)
  • 54 Views
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Article
Single-nucleotide polymorphisms of microRNA processing machinery genes and risk of colorectal cancer
Yufei Zhao, Yanming Du, Shengnan Zhao & Zhanjun Guo
Pages: 421-425
Published online: 12 Feb 2015
AbstractforSingle-nucleotide polymorphisms of microRNA processing machinery genes and risk of colorectal cancer | Full Text | References | PDF (209.8 KB)
  • 88 Views
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Article
Peritumoral SPARC expression and patient outcome with resectable intrahepatic cholangiocarcinoma
Chi-Tung Cheng, Yin-Yi Chu, Chun-Nan Yeh, Shih-Chiang Huang, Ming Huang Chen, Shang-Yu Wang, Chun-Yi Tsai, Kun-Chun Chiang, Yen-Yang Chen, Ming-Chun Ma, Chien-Ting Liu, Tsung-Wen Chen & Ta-Sen Yeh
Pages: 1899-1907
Published online: 28 Jul 2015
AbstractforPeritumoral SPARC expression and patient outcome with resectable intrahepatic cholangiocarcinoma | Full Text | References | PDF (969.4 KB)
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Article
Protective effect of gonadotropin-releasing hormone analog on the ovarian reserve in rats receiving cyclophosphamide treatment
Ting Gui, Guangwen Yuan, Keng Shen, Dongyan Cao, Jiaxin Yang, Ming Wu & Jinghe Lang
Pages: 661-667
Published online: 23 Mar 2015
AbstractforProtective effect of gonadotropin-releasing hormone analog on the ovarian reserve in rats receiving cyclophosphamide treatment | Full Text | References | PDF (1.6 MB)
  • 55 Views
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Article
Treatment and prognosis of Masaoka stage 3 thymic carcinoma: a retrospective study of 32 cases
Yan Sun, Jinshi Liu & Xinmin Yu
Pages: 699-702
Published online: 06 Apr 2015
AbstractforTreatment and prognosis of Masaoka stage 3 thymic carcinoma: a retrospective study of 32 cases | Full Text | References | PDF (317.3 KB)
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Review

Review Article
Profile of nintedanib in the treatment of solid tumors: the evidence to date
Niranjan Awasthi & Roderich E Schwarz
Pages: 3691-3701
Published online: 08 Dec 2015
AbstractforProfile of nintedanib in the treatment of solid tumors: the evidence to date | Full Text | References | PDF (432.1 KB)
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Original Research

Article
Impact of beta-blockers on prostate cancer mortality: a meta-analysis of 16,825 patients
Hua Lu, Xingjie Liu, Fengfu Guo, Shanfeng Tan, Guangjian Wang, Hongjun Liu, Jianming Wang, Xiangfei He, Yanshuai Mo & Benkang Shi
Pages: 985-990
Published online: 30 Apr 2015
AbstractforImpact of beta-blockers on prostate cancer mortality: a meta-analysis of 16,825 patients | Full Text | References | PDF (387.2 KB)
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Article
Validation of the Memorial Sloan Kettering Cancer Center nomogram for predicting non-sentinel lymph node metastasis in sentinel lymph node-positive breast-cancer patients
Xiang Bi, Yongsheng Wang, Minmin Li, Peng Chen, Zhengbo Zhou, Yanbing Liu, Tong Zhao, Zhaopeng Zhang, Chunjian Wang, Xiao Sun & Pengfei Qiu
Pages: 487-493
Published online: 23 Feb 2015
AbstractforValidation of the Memorial Sloan Kettering Cancer Center nomogram for predicting non-sentinel lymph node metastasis in sentinel lymph node-positive breast-cancer patients | Full Text | References | PDF (564.7 KB)
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Case Report

Case Report
A case of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with MET amplification and epithelial-to-mesenchymal transition
Seigo Miyoshi, Takahide Kato, Hitoshi Katayama, Ryoji Ito, Yosuke Mizuno, Takafumi Okura & Jitsuo Higaki
Pages: 783-787
Published online: 09 Apr 2015
AbstractforA case of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with MET amplification and epithelial-to-mesenchymal transition | Full Text | References | PDF (2.6 MB)
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Original Research

Article
An active treatment of lung adenocarcinoma cancer with brain metastases: icotinib
Ying Zhang, Huaping Tang, Jun Li & Meng Li
Pages: 1351-1354
Published online: 08 Jun 2015
AbstractforAn active treatment of lung adenocarcinoma cancer with brain metastases: icotinib | Full Text | References | PDF (1.4 MB)
  • 37 Views
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Article
Gene expression profile analysis of colorectal cancer to investigate potential mechanisms using bioinformatics
Yubin Kou, Suya Zhang, Xiaoping Chen & Sanyuan Hu
Pages: 745-752
Published online: 08 Apr 2015
AbstractforGene expression profile analysis of colorectal cancer to investigate potential mechanisms using bioinformatics | Full Text | References | PDF (1.6 MB)
  • 240 Views
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Article
Comparison of uncommon EGFR exon 21 L858R compound mutations with single mutation
Liang Peng, Zhigang Song & Shunchang Jiao
Pages: 905-910
Published online: 21 Apr 2015
AbstractforComparison of uncommon EGFR exon 21 L858R compound mutations with single mutation | Full Text | References | PDF (376 KB)
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Letter

Letter
A tale of the two PEGylated liposomal doxorubicins
Hunghsueh Chou, Hao Lin & Jacqueline M Liu
Pages: 1719-1720
Published online: 13 Jul 2015
CitationforA tale of the two PEGylated liposomal doxorubicins | Full Text | References | PDF (170.2 KB)
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Original Research

Article
GSTM1 null genotype and gastric cancer risk in the Chinese population: an updated meta-analysis and review
Xi-Liang Zhang & Yong-Hui Cui
Pages: 969-975
Published online: 28 Apr 2015
AbstractforGSTM1 null genotype and gastric cancer risk in the Chinese population: an updated meta-analysis and review | Full Text | References | PDF (420.1 KB)
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Case Report

Case Report
The clue of a possible etiology about spontaneous regression of hepatocellular carcinoma: a perspective on pathology
Zhuo Wang, Zun-Fu Ke, Xiao-Fang Lu, Can-Jiao Luo, Yong-Dong Liu, Zhong-Wei Lin & Lian-Tang Wang
Pages: 395-400
Published online: 05 Feb 2015
AbstractforThe clue of a possible etiology about spontaneous regression of hepatocellular carcinoma: a perspective on pathology | Full Text | References | PDF (3.1 MB)
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Original Research

Article
GSK1838705A, an insulin-like growth factor-1 receptor/insulin receptor inhibitor, induces apoptosis and reduces viability of docetaxel-resistant prostate cancer cells both in vitro and in vivo
Fayou Zhou, Xianguo Chen, Song Fan, Sheng Tai, Changqin Jiang, Yifei Zhang, Zongyao Hao, Jun Zhou, Haoqiang Shi, Li Zhang & Chaozhao Liang
Pages: 753-760
Published online: 10 Apr 2015
AbstractforGSK1838705A, an insulin-like growth factor-1 receptor/insulin receptor inhibitor, induces apoptosis and reduces viability of docetaxel-resistant prostate cancer cells both in vitro and in vivo | Full Text | References | PDF (1.6 MB)
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Article
Comparison of tumor markers using different detection devices
Rong Tao, Shaohua Tu, Chong Liu, Qi Yang, Min Zhu & Jiangfan Shen
Pages: 1083-1090
Published online: 28 Nov 2022
AbstractforComparison of tumor markers using different detection devices | PDF (2.7 MB)
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Review

Review Article
Molecular profiling in the treatment of colorectal cancer: focus on regorafenib
Yiyi Yan & Axel Grothey
Pages: 2949-2957
Published online: 15 Oct 2015
AbstractforMolecular profiling in the treatment of colorectal cancer: focus on regorafenib | Full Text | References | PDF (254.1 KB)
  • 86 Views
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Original Research

Article
Single-nucleotide polymorphisms of microRNA processing machinery genes are associated with risk for gastric cancer
Ying Xie, Yingnan Wang, Yuefei Zhao & Zhanjun Guo
Pages: 567-571
Published online: 04 Mar 2015
AbstractforSingle-nucleotide polymorphisms of microRNA processing machinery genes are associated with risk for gastric cancer | Full Text | References | PDF (211.2 KB)
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Article
Expression and clinical significance of fibroblast growth factor 1 in gastric adenocarcinoma
Naiqing Liu, Jingyu Zhang, Shuxiang Sun, Liguang Yang, Zhongjin Zhou, Qinli Sun & Jun Niu
Pages: 615-621
Published online: 09 Mar 2015
AbstractforExpression and clinical significance of fibroblast growth factor 1 in gastric adenocarcinoma | Full Text | References | PDF (2.3 MB)
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Article
miR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro
Hangzhou Wang, Xue-tao Li, Chun Wu, Zhi-wu Wu, Yan-yan Li, Tian-quan Yang, Gui-lin Chen, Xue-shun Xie, Yu-lun Huang, Zi-wei Du & You-xin Zhou
Pages: 3211-3218
Published online: 28 Nov 2022
AbstractformiR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro | PDF (7.1 MB)
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Article
Transcatheter arterial chemoembolization with gemcitabine and oxaliplatin for the treatment of advanced biliary tract cancer
Qing Zhao, Sheng Qian, Liang Zhu, Xu-Dong Qu, Wei Zhang, Zhi-Ping Yan, Jie-Min Cheng, Qing-Xin Liu, Rong Liu & Jian-Hua Wang
Pages: 595-600
Published online: 09 Mar 2015
AbstractforTranscatheter arterial chemoembolization with gemcitabine and oxaliplatin for the treatment of advanced biliary tract cancer | Full Text | References | PDF (390.3 KB)
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Article
Transforming growth factor-beta-1 is a serum biomarker of radiation-induced pneumonitis in esophageal cancer patients treated with thoracic radiotherapy: preliminary results of a prospective study
Jingxia Li, Shuangfeng Mu, Lixiang Mu, Xiaohui Zhang, Ranran Pang & Shegan Gao
Pages: 1129-1136
Published online: 19 May 2015
AbstractforTransforming growth factor-beta-1 is a serum biomarker of radiation-induced pneumonitis in esophageal cancer patients treated with thoracic radiotherapy: preliminary results of a prospective study | Full Text | References | PDF (454.1 KB)
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Review

Review Article
Diffuse anterior retinoblastoma: current concepts
Jing Yang, Yalong Dang, Yu Zhu & Chun Zhang
Pages: 1815-1821
Published online: 22 Jul 2015
AbstractforDiffuse anterior retinoblastoma: current concepts | Full Text | References | PDF (220.5 KB)
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Original Research

Article
Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase
Malyn M Asuncion Valenzuela, Imilce Castro, Amber Gonda, Carlos J Diaz Osterman, Jessica M Jutzy, Jonathan R Aspe, Salma Khan, Jonathan W Neidigh & Nathan R Wall
Pages: 495-507
Published online: 26 Feb 2015
AbstractforCell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase | Full Text | References | PDF (1.8 MB)
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Review

Review Article
The human immunodeficiency virus protease inhibitor ritonavir is potentially active against urological malignancies
Akinori Sato
Pages: 761-768
Published online: 08 Apr 2015
AbstractforThe human immunodeficiency virus protease inhibitor ritonavir is potentially active against urological malignancies | Full Text | References | PDF (2.8 MB)
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Erratum

Correction
Using an innovative multiple regression procedure in a cancer population (Part I): detecting and probing relationships of common interacting symptoms (pain, fatigue/weakness, sleep problems) as a strategy to discover influential symptom pairs and clusters [Erratum]
Page: 241
Published online: 23 Jan 2015
CitationforUsing an innovative multiple regression procedure in a cancer population (Part I): detecting and probing relationships of common interacting symptoms (pain, fatigue/weakness, sleep problems) as a strategy to discover influential symptom pairs and clusters [Erratum] | Full Text | PDF (101 KB)
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Original Research

Article
Antiproliferative effects and molecular mechanisms of troglitazone in human cervical cancer in vitro
Jinjun Ye, Li Yin, Peng Xie, Jianfeng Wu, Jian Huang, Guoren Zhou, Hanzi Xu, Emei Lu & Xia He
Pages: 1211-1218
Published online: 26 May 2015
AbstractforAntiproliferative effects and molecular mechanisms of troglitazone in human cervical cancer in vitro | Full Text | References | PDF (1.5 MB)
  • 58 Views
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Article
The effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells
Zhongqian Ren, Hui Yang, Cuicui Wang & Xiaoxin Ma
Pages: 769-774
Published online: 09 Apr 2015
AbstractforThe effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells | Full Text | References | PDF (397.5 KB)
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Case Report

Case Report
Combination of icotinib, surgery, and internal-radiotherapy of a patient with lung cancer severely metastasized to the vertebrae bones with EGFR mutation: a case report
Li-Li Qu, Hai-Feng Qin, Hong-Jun Gao & Xiao-Qing Liu
Pages: 1271-1276
Published online: 02 Jun 2015
AbstractforCombination of icotinib, surgery, and internal-radiotherapy of a patient with lung cancer severely metastasized to the vertebrae bones with EGFR mutation: a case report | Full Text | References | PDF (2.8 MB)
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Original Research

Article
Positive feedback between oncogenic KRAS and HIF-1α confers drug resistance in colorectal cancer
Yanzhao Wang, Fuming Lei, Wanshui Rong, Qingmin Zeng & Wenbing Sun
Pages: 1229-1237
Published online: 26 May 2015
AbstractforPositive feedback between oncogenic KRAS and HIF-1α confers drug resistance in colorectal cancer | Full Text | References | PDF (2.1 MB)
  • 73 Views
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Article
BMS-536924, an ATP-competitive IGF-1R/IR inhibitor, decreases viability and migration of temozolomide-resistant glioma cells in vitro and suppresses tumor growth in vivo
Qiao Zhou
Pages: 689-697
Published online: 02 Apr 2015
AbstractforBMS-536924, an ATP-competitive IGF-1R/IR inhibitor, decreases viability and migration of temozolomide-resistant glioma cells in vitro and suppresses tumor growth in vivo | Full Text | References | PDF (2.6 MB)
  • 60 Views
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Article
Identification of the key genes connected with plasma cells of multiple myeloma using expression profiles
Kefeng Zhang, Zhongyang Xu & Zhaoyun Sun
Pages: 1795-1803
Published online: 20 Jul 2015
AbstractforIdentification of the key genes connected with plasma cells of multiple myeloma using expression profiles | Full Text | References | PDF (2.2 MB)
  • 65 Views
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Article
miR-205 suppresses the proliferative and migratory capacity of human osteosarcoma Mg-63 cells by targeting VEGFA
Li Wang, Minhong Shan, Yang Liu, Fengyi Yang, Hongxia Qi, Lijuan Zhou, Lirong Qiu & Yanshuang Li
Pages: 2635-2642
Published online: 16 Sep 2015
AbstractformiR-205 suppresses the proliferative and migratory capacity of human osteosarcoma Mg-63 cells by targeting VEGFA | Full Text | References | PDF (1.8 MB)
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Case Report

Case Report
A recurrent ovarian cancer patient with a history of nine prior chemotherapy regimens who was safely treated with weekly paclitaxel plus bevacizumab and achieved a complete response: a case report
Eriko Takatori, Tadahiro Shoji, Takayuki Nagasawa, Satoshi Takeuchi, Akira Hosoyachi & Toru Sugiyama
Pages: 2097-2100
Published online: 11 Aug 2015
AbstractforA recurrent ovarian cancer patient with a history of nine prior chemotherapy regimens who was safely treated with weekly paclitaxel plus bevacizumab and achieved a complete response: a case report | Full Text | References | PDF (705 KB)
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Original Research

Article
Bevacizumab plus cisplatin and helical tomotherapy in treatment of locally advanced nasopharyngeal carcinoma
Jianxiong Li, Zhifei Zhao, Xuan Wu, Jie Yao, Lin Ma, Rui Ye, Baolong Niu, Lanqing Liang, Xiao Zhao & Qianqian Wang
Pages: 1315-1319
Published online: 02 Jun 2015
AbstractforBevacizumab plus cisplatin and helical tomotherapy in treatment of locally advanced nasopharyngeal carcinoma | Full Text | References | PDF (280.8 KB)
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Article
IL-27 rs153109 polymorphism increases the risk of colorectal cancer in Chinese Han population
Shixu Lyu, Lechi Ye, Ouchen Wang, Guanli Huang, Fan Yang, Yehuan Liu & Siyang Dong
Pages: 1493-1497
Published online: 16 Jun 2015
AbstractforIL-27 rs153109 polymorphism increases the risk of colorectal cancer in Chinese Han population | Full Text | References | PDF (596.4 KB)
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Article
The effect of ataxia-telangiectasia mutated kinase-dependent hyperphosphorylation of checkpoint kinase-2 on oligodeoxynucleotide 7909 containing CpG motifs-enhanced sensitivity to X-rays in human lung adenocarcinoma A549 cells
Xiaoqun Liu, Xiangdong Liu, Tiankui Qiao, Wei Chen & Sujuan Yuan
Pages: 1399-1406
Published online: 10 Jun 2015
AbstractforThe effect of ataxia-telangiectasia mutated kinase-dependent hyperphosphorylation of checkpoint kinase-2 on oligodeoxynucleotide 7909 containing CpG motifs-enhanced sensitivity to X-rays in human lung adenocarcinoma A549 cells | Full Text | References | PDF (2.6 MB)
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Review

Review Article
Association of the CYP24A1-rs2296241 polymorphism of the vitamin D catabolism enzyme with hormone-related cancer risk: a meta-analysis
Ping Wang, Hemei Zhang, Zengli Zhang, Liqiang Qin & Bingyan Li
Pages: 1175-1183
Published online: 22 May 2015
AbstractforAssociation of the CYP24A1-rs2296241 polymorphism of the vitamin D catabolism enzyme with hormone-related cancer risk: a meta-analysis | Full Text | References | PDF (768.5 KB)
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Original Research

Article
Outcome of surgical resection for brain metastases and radical treatment of the primary tumor in Chinese non–small-cell lung cancer patients
Zhenye Li, Xiangheng Zhang, Xiaobing Jiang, Chengcheng Guo, Ke Sai, Qunying Yang, Zhenqiang He, Yang Wang, Zhongping Chen, Wei Li & Yonggao Mou
Pages: 855-860
Published online: 16 Apr 2015
AbstractforOutcome of surgical resection for brain metastases and radical treatment of the primary tumor in Chinese non–small-cell lung cancer patients | Full Text | References | PDF (504.8 KB)
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Corrigendum

Correction
Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells [Corrigendum]
Page: 365
Published online: 28 Nov 2022
CitationforDisruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells [Corrigendum] | Full Text | PDF (101.4 KB)
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Review

Review Article
Enzalutamide for patients with metastatic castration-resistant prostate cancer
Wijdan H Ramadan, Wissam K Kabbara & Hiba S Al Basiouni Al Masri
Pages: 871-876
Published online: 17 Apr 2015
AbstractforEnzalutamide for patients with metastatic castration-resistant prostate cancer | Full Text | References | PDF (211.3 KB)
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Original Research

Article
The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab
Shu-Dong Zhang, Cian M McCrudden, Chen Meng, Yao Lin & Hang Fai Kwok
Pages: 835-843
Published online: 15 Apr 2015
AbstractforThe significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab | Full Text | References | PDF (1.2 MB)
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Corrigendum

Correction
Outcomes analysis of an alternative formulation of PEGylated liposomal doxorubicin in recurrent epithelial ovarian carcinoma during the drug shortage era [Corrigendum]
Page: 593
Published online: 09 Mar 2015
CitationforOutcomes analysis of an alternative formulation of PEGylated liposomal doxorubicin in recurrent epithelial ovarian carcinoma during the drug shortage era [Corrigendum] | Full Text | PDF (97.1 KB)
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Review

Review Article
Prognostic role of urokinase plasminogen activator receptor in gastric and colorectal cancer: A systematic review and meta-analysis
Hong Guo, Chun Ling, Yun-yun Ma, Lan-xia Zhou & Li Zhao
Pages: 1503-1509
Published online: 19 Jun 2015
AbstractforPrognostic role of urokinase plasminogen activator receptor in gastric and colorectal cancer: A systematic review and meta-analysis | Full Text | References | PDF (645.3 KB)
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Original Research

Article
Computer-aided classification of lung nodules on computed tomography images via deep learning technique
Kai-Lung Hua, Che-Hao Hsu, Shintami Chusnul Hidayati, Wen-Huang Cheng & Yu-Jen Chen
Pages: 2015-2022
Published online: 04 Aug 2015
AbstractforComputer-aided classification of lung nodules on computed tomography images via deep learning technique | Full Text | References | PDF (946.2 KB)
  • 911 Views
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Article
DNA ploidy of cervical epithelial cells should be a cure criterion of high-risk HPV infection in Xinjiang Uygur women
Yang-Chun Feng, Jia Yang, Cheng-Ming Liu, Zhen-Zhen Cheng & Yan-Chun Huang
Pages: 827-833
Published online: 13 Apr 2015
AbstractforDNA ploidy of cervical epithelial cells should be a cure criterion of high-risk HPV infection in Xinjiang Uygur women | Full Text | References | PDF (387.2 KB)
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Case Report

Case Report
Primary paraesophageal Ewing’s sarcoma: an uncommon case report and literature review
Noelia Tarazona, Lara Navarro, Juan Miguel Cejalvo, Valentina Gambardella, J Alejandro Pérez-Fidalgo, Alejo Sempere, Samuel Navarro & Andrés Cervantes
Pages: 1053-1059
Published online: 14 May 2015
AbstractforPrimary paraesophageal Ewing’s sarcoma: an uncommon case report and literature review | Full Text | References | PDF (2.4 MB)
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Original Research

Article
Association between the ERCC1 rs11615 polymorphism and clinical outcomes of oxaliplatin-based chemotherapies in gastrointestinal cancer: a meta-analysis
Shou-Cheng Ma, Yue Zhao, Tao Zhang, Xiao-Ling Ling & Da Zhao
Pages: 641-648
Published online: 16 Mar 2015
AbstractforAssociation between the ERCC1 rs11615 polymorphism and clinical outcomes of oxaliplatin-based chemotherapies in gastrointestinal cancer: a meta-analysis | Full Text | References | PDF (464.6 KB)
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Article
Adipose tissue-secreted miR-27a promotes liver cancer by targeting FOXO1 in obese individuals
Baozhen Sun, Jing Li, Dan Shao, Yue Pan, Yujing Chen, Suo Li, Xiaoxiao Yao, Hang Li, Weiwei Liu, Ming Zhang, Xuewen Zhang & Li Chen
Pages: 735-744
Published online: 07 Apr 2015
AbstractforAdipose tissue-secreted miR-27a promotes liver cancer by targeting FOXO1 in obese individuals | Full Text | References | PDF (2.2 MB)
  • 70 Views
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Article
The clinical activity of arsenic trioxide, ascorbic acid, ifosfamide and prednisone combination therapy in patients with relapsed and refractory multiple myeloma
Xin Li & Wan-Jun Sun
Pages: 775-781
Published online: 09 Apr 2015
AbstractforThe clinical activity of arsenic trioxide, ascorbic acid, ifosfamide and prednisone combination therapy in patients with relapsed and refractory multiple myeloma | Full Text | References | PDF (589.4 KB)
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Article
Artesunate inhibits the growth and induces apoptosis of human gastric cancer cells by downregulating COX-2
Ping Zhang, He-Sheng Luo, Ming Li & Shi-yun Tan
Pages: 845-854
Published online: 16 Apr 2015
AbstractforArtesunate inhibits the growth and induces apoptosis of human gastric cancer cells by downregulating COX-2 | Full Text | References | PDF (8.6 MB)
  • 114 Views
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Review

Review Article
Spotlight on decitabine for myelodysplastic syndromes in Chinese patients
Yu Jing, Xue Shen, Qian Mei & Weidong Han
Pages: 2783-2790
Published online: 03 Oct 2015
AbstractforSpotlight on decitabine for myelodysplastic syndromes in Chinese patients | Full Text | References | PDF (268.5 KB)
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Original Research

Article
Association between GSTP1 polymorphisms and prognosis of osteosarcoma in patients treated with chemotherapy: a meta-analysis
Feifei Pu, Fengxia Chen, Songfeng Chen, Baichuan Wang, Jianxiang Liu & Zengwu Shao
Pages: 1835-1842
Published online: 23 Jul 2015
AbstractforAssociation between GSTP1 polymorphisms and prognosis of osteosarcoma in patients treated with chemotherapy: a meta-analysis | Full Text | References | PDF (916.5 KB)
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Article
High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer
Tao Han, Zhaozhe Liu, Hengyu Li, Wanqing Xie, Ranran Zhang, Li Zhu, Fang Guo, Yaling Han, Yuan Sheng & Xiaodong Xie
Pages: 1643-1649
Published online: 06 Jul 2015
AbstractforHigh expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer | Full Text | References | PDF (982 KB)
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Article
A chromosomal passenger complex protein signature model predicts poor prognosis for non-small-cell lung cancer
Rong Xia, Sunxiao Chen, Yan Chen, Weiwei Zhang, Rongrong Zhu & Anmei Deng
Pages: 721-726
Published online: 07 Apr 2015
AbstractforA chromosomal passenger complex protein signature model predicts poor prognosis for non-small-cell lung cancer | Full Text | References | PDF (2.9 MB)
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Article
Knockdown of a HIF-2α promoter upstream long noncoding RNA impairs colorectal cancer stem cell properties in vitro through HIF-2α downregulation
Jie Yao, Jianxiong Li, Peiliang Geng, Yi Li, Hong Chen & Yunfeng Zhu
Pages: 3467-3474
Published online: 25 Nov 2015
AbstractforKnockdown of a HIF-2α promoter upstream long noncoding RNA impairs colorectal cancer stem cell properties in vitro through HIF-2α downregulation | Full Text | References | PDF (1.3 MB)
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Article
A randomized Phase II clinical study of combining panitumumab and bevacizumab, plus irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) compared with FOLFIRI alone as second-line treatment for patients with metastatic colorectal cancer and KRAS mutation
Yuguo Liu, Lijuan Luan & Xingli Wang
Pages: 1061-1068
Published online: 14 May 2015
AbstractforA randomized Phase II clinical study of combining panitumumab and bevacizumab, plus irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) compared with FOLFIRI alone as second-line treatment for patients with metastatic colorectal cancer and KRAS mutation | Full Text | References | PDF (472.7 KB)
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Study Protocol

Article
Role of integrin-linked kinase in drug resistance of lung cancer
Zhiyang Jia
Pages: 1561-1565
Published online: 23 Jun 2015
AbstractforRole of integrin-linked kinase in drug resistance of lung cancer | Full Text | References | PDF (618 KB)
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Case Report

Case Report
Inactivity of imatinib in gastrointestinal stromal tumors (GISTs) harboring a KIT activation-loop domain mutation (exon 17 mutation pN822K)
Gianluca Spitaleri, Roberto Biffi, Massimo Barberis, Caterina Fumagalli, Francesca Toffalorio, Chiara Catania, Cristina Noberasco, Chiara Lazzari, Filippo de Marinis & Tommaso De Pas
Pages: 1997-2003
Published online: 18 Aug 2015
AbstractforInactivity of imatinib in gastrointestinal stromal tumors (GISTs) harboring a KIT activation-loop domain mutation (exon 17 mutation pN822K) | Full Text | References | PDF (2 MB)
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Original Research

Article
Screening of potential diagnostic markers and therapeutic targets against colorectal cancer
XiaoQing Tian, DanFeng Sun, ShuLiang Zhao, Hua Xiong & JingYuan Fang
Pages: 1691-1699
Published online: 08 Jul 2015
AbstractforScreening of potential diagnostic markers and therapeutic targets against colorectal cancer | Full Text | References | PDF (433.2 KB)
  • 113 Views
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Article
The prognostic significance of fibroblast growth factor receptor 4 in non-small-cell lung cancer
Hong-ping Huang, Hui Feng, Hong-bo Qiao, Ze-xiang Ren & Ge-dong Zhu
Pages: 1157-1164
Published online: 22 May 2015
AbstractforThe prognostic significance of fibroblast growth factor receptor 4 in non-small-cell lung cancer | Full Text | References | PDF (2 MB)
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Review

Review Article
Microwave ablation: state-of-the-art review
José Irving Hernández, Mario Francisco Jesús Cepeda, Francisco Valdés & Geshel David Guerrero
Pages: 1627-1632
Published online: 06 Jul 2015
AbstractforMicrowave ablation: state-of-the-art review | Full Text | References | PDF (1.2 MB)
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Review Article
Clinical and pathological analysis of 116 cases of adult adrenal cortical adenoma and literature review
Ai-Hua Jia, Hong-Quan Du, Min-Hua Fan, Yu-Hong Li, Jun-Long Xu, Gui-Fen Niu, Jie Bai, Guang-Zhen Zhang & Yu-Bo Ren
Pages: 1251-1257
Published online: 28 May 2015
AbstractforClinical and pathological analysis of 116 cases of adult adrenal cortical adenoma and literature review | Full Text | References | PDF (940.1 KB)
  • 71 Views
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Original Research

Article
Comparison of single-agent chemotherapy and targeted therapy to first-line treatment in patients aged 80 years and older with advanced non-small-cell lung cancer
Qianqian Zhang, Zhehai Wang, Jun Guo, Liyan Liu, Xiao Han, Minmin Li, Shu Fang, Xiang Bi, Ning Tang & Yang Liu
Pages: 893-898
Published online: 20 Apr 2015
AbstractforComparison of single-agent chemotherapy and targeted therapy to first-line treatment in patients aged 80 years and older with advanced non-small-cell lung cancer | Full Text | References | PDF (546.4 KB)
  • 60 Views
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Article
Value of detection of serum human epididymis secretory protein 4 and carbohydrate antigen 125 in diagnosis of early endometrial cancer of different pathological subtypes
Xingui Liu, Fengting Zhao, Linli Hu & Yingpu Sun
Pages: 1239-1243
Published online: 26 May 2015
AbstractforValue of detection of serum human epididymis secretory protein 4 and carbohydrate antigen 125 in diagnosis of early endometrial cancer of different pathological subtypes | Full Text | References | PDF (294.8 KB)
  • 54 Views
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Article
Expression of Fascin-1 on human lung cancer and paracarcinoma tissue and its relation to clinicopathological characteristics in patients with lung cancer
Wei Zhao, Jing Gao, Jing Wu, Qiu-hong Liu, Zhi-gang Wang, Hui-ling Li & Li-hua Xing
Pages: 2571-2576
Published online: 15 Sep 2015
AbstractforExpression of Fascin-1 on human lung cancer and paracarcinoma tissue and its relation to clinicopathological characteristics in patients with lung cancer | Full Text | References | PDF (1.1 MB)
  • 87 Views
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Article
Effect of blood type on survival of Chinese patients with esophageal squamous cell carcinoma
Jian Qin, San-Gang Wu, Jia-Yuan Sun, Huan-Xin Lin, Zhen-Yu He & Qun Li
Pages: 947-953
Published online: 23 Apr 2015
AbstractforEffect of blood type on survival of Chinese patients with esophageal squamous cell carcinoma | Full Text | References | PDF (519.4 KB)
  • 48 Views
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Article
Analysis of clinical efficacy of CyberKnife® treatment for locally advanced pancreatic cancer
Yongchun Song, Zhiyong Yuan, Fengtong Li, Yang Dong, Hongqing Zhuang, Jingsheng Wang, Huaming Chen & Ping Wang
Pages: 1427-1431
Published online: 12 Jun 2015
AbstractforAnalysis of clinical efficacy of CyberKnife® treatment for locally advanced pancreatic cancer | Full Text | References | PDF (828.8 KB)
  • 163 Views
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Article
Evaluation and comparison of two commercially available targeted next-generation sequencing platforms to assist oncology decision making
Glen J Weiss, Brandi R Hoff, Robert P Whitehead, Ashish Sangal, Susan A Gingrich, Robert J Penny, David W Mallery, Scott M Morris, Eric J Thompson, David M Loesch & Vivek Khemka
Pages: 959-967
Published online: 24 Apr 2015
AbstractforEvaluation and comparison of two commercially available targeted next-generation sequencing platforms to assist oncology decision making | Full Text | References | PDF (527.9 KB)
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Article
Effect of radiotherapy on survival of women with locally excised ductal carcinoma in situ of the breast: a Surveillance, Epidemiology, and End Results population-based analysis
Guo-Wei Qian, Xiao-Jian Ni, Zheng Wang, Yi-Zhou Jiang, Ke-Da Yu & Zhi-Ming Shao
Pages: 1407-1418
Published online: 10 Jun 2015
AbstractforEffect of radiotherapy on survival of women with locally excised ductal carcinoma in situ of the breast: a Surveillance, Epidemiology, and End Results population-based analysis | Full Text | References | PDF (604.7 KB)
  • 50 Views
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Article
Exploration of peptide T7 and its derivative as integrin αvβ3-targeted imaging agents
Xin He, Yumei Hao, Wei Long, Naling Song, Saijun Fan & Aimin Meng
Pages: 1483-1491
Published online: 15 Jun 2015
AbstractforExploration of peptide T7 and its derivative as integrin αvβ3-targeted imaging agents | Full Text | References | PDF (1.5 MB)
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Article
ABCB1 C3435T polymorphism is associated with leukemia susceptibility: evidence from a meta-analysis
Limin Ma, Linhai Ruan, Hongchao Liu, Haiping Yang & Yanming Feng
Pages: 1009-1015
Published online: 05 May 2015
AbstractforABCB1 C3435T polymorphism is associated with leukemia susceptibility: evidence from a meta-analysis | Full Text | References | PDF (690.7 KB)
  • 53 Views
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Article
GCDFP-15, AR, and Her-2 as biomarkers for primary ductal adenocarcinoma of the lacrimal gland: a Chinese case and literature review
Miao-Miao Zhu, Hong-Guang Cui & Xiao-Dong Teng
Pages: 1017-1024
Published online: 11 May 2015
AbstractforGCDFP-15, AR, and Her-2 as biomarkers for primary ductal adenocarcinoma of the lacrimal gland: a Chinese case and literature review | Full Text | References | PDF (7.2 MB)
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Article
Decreased pretreatment lymphocyte/monocyte ratio is associated with poor prognosis in stage Ib1–IIa cervical cancer patients who undergo radical surgery
Liang Chen, Fang Zhang, Xiu-gui Sheng & Shi-qian Zhang
Pages: 1355-1362
Published online: 08 Jun 2015
AbstractforDecreased pretreatment lymphocyte/monocyte ratio is associated with poor prognosis in stage Ib1–IIa cervical cancer patients who undergo radical surgery | Full Text | References | PDF (590.8 KB)
  • 61 Views
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Article
Protein tyrosine phosphatase SHP-1 sensitizes EGFR/HER-2 positive breast cancer cells to trastuzumab through modulating phosphorylation of EGFR and HER-2
Yifen Wu, Rong Li, Junyi Zhang, Gang Wang, Bin Liu, Xiaofang Huang, Tao Zhang & Rongcheng Luo
Pages: 2577-2587
Published online: 14 Sep 2015
AbstractforProtein tyrosine phosphatase SHP-1 sensitizes EGFR/HER-2 positive breast cancer cells to trastuzumab through modulating phosphorylation of EGFR and HER-2 | Full Text | References | PDF (2.3 MB)
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Article
Anterior gradient protein 3 is associated with less aggressive tumors and better outcome of breast cancer patients
Joanna Obacz, Veronika Brychtova, Jan Podhorec, Pavel Fabian, Petr Dobes, Borivoj Vojtesek & Roman Hrstka
Pages: 1523-1532
Published online: 24 Jun 2015
AbstractforAnterior gradient protein 3 is associated with less aggressive tumors and better outcome of breast cancer patients | Full Text | References | PDF (1.1 MB)
  • 61 Views
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Article
Elevated pretreatment plasma D-dimer levels and platelet counts predict poor prognosis in pancreatic adenocarcinoma
Peng Liu, Yuan Zhu & Luying Liu
Pages: 1335-1340
Published online: 04 Jun 2015
AbstractforElevated pretreatment plasma D-dimer levels and platelet counts predict poor prognosis in pancreatic adenocarcinoma | Full Text | References | PDF (432.7 KB)
  • 67 Views
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Article
Progression-free survival as a surrogate endpoint for overall survival in patients with third-line or later-line chemotherapy for advanced gastric cancer
Liya Liu, Hao Yu, Lihong Huang, Fang Shao, Jianling Bai, Donghua Lou & Feng Chen
Pages: 921-928
Published online: 22 Apr 2015
AbstractforProgression-free survival as a surrogate endpoint for overall survival in patients with third-line or later-line chemotherapy for advanced gastric cancer | Full Text | References | PDF (346.5 KB)
  • 61 Views
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Article
SIRT1 expression is associated with poor prognosis of lung adenocarcinoma
Chong Li, Lingling Wang, Liang Zheng, Xianghong Zhan, Bin Xu, Jingting Jiang & Changping Wu
Pages: 977-984
Published online: 30 Apr 2015
AbstractforSIRT1 expression is associated with poor prognosis of lung adenocarcinoma | Full Text | References | PDF (2.3 MB)
  • 72 Views
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Article
Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade
Ke Yin
Pages: 1069-1074
Published online: 14 May 2015
AbstractforPositive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade | Full Text | References | PDF (2.7 MB)
  • 59 Views
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Article
A comparison of the prognostic value of preoperative inflammation-based scores and TNM stage in patients with gastric cancer
Qun-Xiong Pan, Zi-Jian Su, Jian-Hua Zhang, Chong-Ren Wang & Shao-Ying Ke
Pages: 1375-1385
Published online: 16 Jun 2015
AbstractforA comparison of the prognostic value of preoperative inflammation-based scores and TNM stage in patients with gastric cancer | Full Text | References | PDF (716.9 KB)
  • 88 Views
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Article
Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma
Lei Cheng, Zuguang Xia, Xinyu Bian, Guangchao Li, Jing Hu, Ya Cao, Qing Wang & Xiaoping Qian
Pages: 3185-3192
Published online: 02 Nov 2015
AbstractforCombination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma | Full Text | References | PDF (1.6 MB)
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Study Protocol

Article
Single-port versus conventional multiport access prophylactic laparoscopic bilateral salpingo-oophorectomy in high-risk patients for ovarian cancer: a comparison of surgical outcomes
Stefano Angioni, Alessandro Pontis, Federica Sedda, Theodoros Zampetoglou, Vito Cela, Liliana Mereu & Pietro Litta
Pages: 1575-1580
Published online: 25 Jun 2015
AbstractforSingle-port versus conventional multiport access prophylactic laparoscopic bilateral salpingo-oophorectomy in high-risk patients for ovarian cancer: a comparison of surgical outcomes | Full Text | References | PDF (352.7 KB)
  • 57 Views
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Original Research

Article
Enhanced NK cell adoptive antitumor effects against breast cancer in vitro via blockade of the transforming growth factor-β signaling pathway
Yue Zhao, Jinyue Hu, Rongguo Li, Jian Song, Yujuan Kang, Si Liu & Dongwei Zhang
Pages: 1553-1559
Published online: 22 Jun 2015
AbstractforEnhanced NK cell adoptive antitumor effects against breast cancer in vitro via blockade of the transforming growth factor-β signaling pathway | Full Text | References | PDF (1.3 MB)
  • 77 Views
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Review

Review Article
Tracking the 2015 Gastrointestinal Cancers Symposium: bridging cancer biology to clinical gastrointestinal oncology
Giuseppe Aprile, Francesco Leone, Riccardo Giampieri, Mariaelena Casagrande, Donatella Marino, Luca Faloppi, Stefano Cascinu, Gianpiero Fasola & Mario Scartozzi
Pages: 1149-1156
Published online: 22 May 2015
AbstractforTracking the 2015 Gastrointestinal Cancers Symposium: bridging cancer biology to clinical gastrointestinal oncology | Full Text | References | PDF (232.3 KB)
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Case Report

Case Report
Sudden bilateral hearing loss in gastric cancer as the only symptom of disease
Zoran Rakusic, Ana Misir Krpan, Darija Stupin Polancec, Antonia Jakovcevic & Vesna Bisof
Pages: 1285-1289
Published online: 02 Jun 2015
AbstractforSudden bilateral hearing loss in gastric cancer as the only symptom of disease | Full Text | References | PDF (825.3 KB)
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Original Research

Article
FH535 inhibited metastasis and growth of pancreatic cancer cells
Meng-Yao Wu, Rong-Rui Liang, Kai Chen, Meng Shen, Ya-Li Tian, Dao-Ming Li, Wei-Ming Duan, Qi Gui, Fei-Ran Gong, Lian Lian, Wei Li & Min Tao
Pages: 1651-1670
Published online: 06 Jul 2015
AbstractforFH535 inhibited metastasis and growth of pancreatic cancer cells | Full Text | References | PDF (4 MB)
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Article
Hypoxia-inducible factor-1α induces multidrug resistance protein in colon cancer
Yingqian Lv, Shan Zhao, Jinzhu Han, Likang Zheng, Zixin Yang & Li Zhao
Pages: 1941-1948
Published online: 29 Jul 2015
AbstractforHypoxia-inducible factor-1α induces multidrug resistance protein in colon cancer | Full Text | References | PDF (591.5 KB)
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Article
O-GlcNAcylation enhances the invasion of thyroid anaplastic cancer cells partially by PI3K/Akt1 pathway
Peng Zhang, Chunli Wang, Tao Ma & Shengyi You
Pages: 3305-3313
Published online: 09 Nov 2015
AbstractforO-GlcNAcylation enhances the invasion of thyroid anaplastic cancer cells partially by PI3K/Akt1 pathway | Full Text | References | PDF (1.6 MB)
  • 78 Views
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Case Report

Case Report
Metastatic medullary thyroid cancer: a dramatic response to a systemic chemotherapy (temozolomide and capecitabine) regimen
Sahin Lacin, Ece Esin, Yusuf Karakas & Suayib Yalcin
Pages: 1039-1042
Published online: 13 May 2015
AbstractforMetastatic medullary thyroid cancer: a dramatic response to a systemic chemotherapy (temozolomide and capecitabine) regimen | Full Text | References | PDF (262.2 KB)
  • 62 Views
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Review

Review Article
Risks on N-acetyltransferase 2 and bladder cancer: a meta-analysis
Zongheng Zhu, Jinshan Zhang, Wei Jiang, Xianjue Zhang, Youkong Li & Xiaoming Xu
Pages: 3715-3720
Published online: 11 Dec 2015
AbstractforRisks on N-acetyltransferase 2 and bladder cancer: a meta-analysis | Full Text | References | PDF (530.4 KB)
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Original Research

Article
Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis
Chia-Ying Lien, Tai-Yuan Chuang, Chih-Hsiang Hsu, Ching-Lung Lin, Sheue-Er Wang, Shuenn-Jyi Sheu, Chiang-Ting Chien & Chung-Hsin Wu
Pages: 1193-1210
Published online: 26 May 2015
AbstractforOral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis | Full Text | References | PDF (5 MB)
  • 52 Views
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Article
Clinical and prognostic significance of pathological and inflammatory markers in the surgical treatment of locally advanced colorectal cancer
M Sokolov, K Angelov, M Vasileva, MP Atanasova, A Vlahova & G Todorov
Pages: 2329-2337
Published online: 01 Sep 2015
AbstractforClinical and prognostic significance of pathological and inflammatory markers in the surgical treatment of locally advanced colorectal cancer | Full Text | References | PDF (1.1 MB)
  • 67 Views
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Article
Association between promoter polymorphisms of matrix metalloproteinase-1 and risk of gastric cancer
Qisong Peng & Yong Xu
Pages: 2519-2526
Published online: 10 Sep 2015
AbstractforAssociation between promoter polymorphisms of matrix metalloproteinase-1 and risk of gastric cancer | Full Text | References | PDF (553.6 KB)
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Study Protocol

Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer
Sachio Fushida, Masahide Kaji, Katsunobu Oyama, Yasuo Hirono, Hideaki Nezuka, Toshiya Takeda, Tomoya Tsukada, Daisuke Fujimoto, Shigekazu Ohyama, Takashi Fujimura, Tetsuo Ohta & On behalf of the Digestive Disease Support Organization (DDSO)
Pages: 939-941
Published online: 23 Apr 2015
AbstractforRandomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer | Full Text | References | PDF (139.1 KB)
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Original Research

Article
An analysis of brachytherapy with computed tomography-guided permanent implantation of Iodine-125 seeds for recurrent nonkeratin nasopharyngeal carcinoma
Xinying Shen, Yong Li, Yanfang Zhang, Jian Kong & Yanhao Li
Pages: 991-997
Published online: 02 May 2015
AbstractforAn analysis of brachytherapy with computed tomography-guided permanent implantation of Iodine-125 seeds for recurrent nonkeratin nasopharyngeal carcinoma | Full Text | References | PDF (878.4 KB)
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Article
Alectinib for choroidal metastasis in a patient with crizotinib-resistant ALK rearranged positive non-small cell lung cancer
Yusuke Okuma, Yuichiro Tanaka, Tina Kamei, Yukio Hosomi & Tatsuru Okamura
Pages: 1321-1325
Published online: 03 Jun 2015
AbstractforAlectinib for choroidal metastasis in a patient with crizotinib-resistant ALK rearranged positive non-small cell lung cancer | Full Text | References | PDF (2 MB)
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Article
Evaluation of the pathological response and prognosis following neoadjuvant chemotherapy in molecular subtypes of breast cancer
Yue Zhao, Xiaoqiu Dong, Rongguo Li, Xiao Ma, Jian Song, Yingjie Li & Dongwei Zhang
Pages: 1511-1521
Published online: 19 Jun 2015
AbstractforEvaluation of the pathological response and prognosis following neoadjuvant chemotherapy in molecular subtypes of breast cancer | Full Text | References | PDF (805.9 KB)
  • 132 Views
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Article
Axitinib versus sorafenib as a second-line therapy in Asian patients with metastatic renal cell carcinoma: results from a randomized registrational study
Shukui Qin, Feng Bi, Jie Jin, Ying Cheng, Jun Guo, Xiubao Ren, Yiran Huang, Jamal Tarazi, Jie Tang, Connie Chen, Sinil Kim & Dingwei Ye
Pages: 1363-1373
Published online: 08 Jun 2015
AbstractforAxitinib versus sorafenib as a second-line therapy in Asian patients with metastatic renal cell carcinoma: results from a randomized registrational study | Full Text | References | PDF (551.6 KB)
  • 136 Views
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Article
Clinical analysis of 50 Eastern Asian patients with primary pulmonary large-cell neuroendocrine carcinoma
Xin-ke Zhang, Tao Qin, Yin-duo Zeng, Yuan-yuan Zhao, Xue Hou, Wen-feng Fang, Shao-dong Hong, Ting Zhou, Zhi-huang Hu, Yun-peng Yang, Yu-xiang Ma, Cong Xue, Yan Huang, Hong-yun Zhao & Li Zhang
Pages: 1219-1227
Published online: 26 May 2015
AbstractforClinical analysis of 50 Eastern Asian patients with primary pulmonary large-cell neuroendocrine carcinoma | Full Text | References | PDF (804.5 KB)
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Article
Evaluation of clinical breast examination and breast ultrasonography among pregnant women in Abakaliki, Nigeria
Paul Olisaemeka Ezeonu, Leonard Ogbonna Ajah, Robinson Chukwudi Onoh, Lucky Osaheni Lawani, Vincent Chidi Enemuo & Uzoma MaryRose Agwu
Pages: 1025-1029
Published online: 13 May 2015
AbstractforEvaluation of clinical breast examination and breast ultrasonography among pregnant women in Abakaliki, Nigeria | Full Text | References | PDF (212.4 KB)
  • 100 Views
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Article
The expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer
Hong-shan Wang & Li-hong Wang
Pages: 1893-1898
Published online: 27 Jul 2015
AbstractforThe expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer | Full Text | References | PDF (665.4 KB)
  • 58 Views
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Article
HES1 is an independent prognostic factor for acute myeloid leukemia
Chen Tian, Yingjun Tang, Tengteng Wang, Yong Yu, Xiaofang Wang, Yafei Wang & Yizhuo Zhang
Pages: 899-904
Published online: 22 Apr 2015
AbstractforHES1 is an independent prognostic factor for acute myeloid leukemia | Full Text | References | PDF (836.8 KB)
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Review

Review Article
Phytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancers
Roxana Cojocneanu Petric, Cornelia Braicu, Lajos Raduly, Oana Zanoaga, Nicolae Dragos, Paloma Monroig, Dan Dumitrascu & Ioana Berindan-Neagoe
Pages: 2053-2066
Published online: 06 Aug 2015
AbstractforPhytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancers | Full Text | References | PDF (1.3 MB)
  • 236 Views
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Original Research

Article
Circulating VEGF as a biomarker for diagnosis of ovarian cancer: a systematic review and a meta-analysis
Bin Liang, Qun He, Liansheng Zhong, Shaocheng Wang, Zhongcheng Pan, Tianjiao Wang & Yujie Zhao
Pages: 1075-1082
Published online: 15 May 2015
AbstractforCirculating VEGF as a biomarker for diagnosis of ovarian cancer: a systematic review and a meta-analysis | Full Text | References | PDF (1.2 MB)
  • 87 Views
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Article
Daily rhythm variations of the clock gene PER1 and cancer-related genes during various stages of carcinogenesis in a golden hamster model of buccal mucosa carcinoma
Hua Ye, Kai Yang, Xue-Mei Tan, Xiao-Juan Fu & Han-Xue Li
Pages: 1419-1426
Published online: 11 Jun 2015
AbstractforDaily rhythm variations of the clock gene PER1 and cancer-related genes during various stages of carcinogenesis in a golden hamster model of buccal mucosa carcinoma | Full Text | References | PDF (890.7 KB)
  • 61 Views
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Article
Genetic polymorphisms of PAI-1 and PAR-1 are associated with acute normal tissue toxicity in Chinese rectal cancer patients treated with pelvic radiotherapy
Hui Zhang, Mengyun Wang, Tingyan Shi, Lijun Shen, Ji Zhu, Menghong Sun, Yun Deng, Liping Liang, Guichao Li, Yongxin Wu, Ming Fan, Qingyi Wei & Zhen Zhang
Pages: 2291-2301
Published online: 27 Aug 2015
AbstractforGenetic polymorphisms of PAI-1 and PAR-1 are associated with acute normal tissue toxicity in Chinese rectal cancer patients treated with pelvic radiotherapy | Full Text | References | PDF (505.1 KB)
  • 54 Views
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Article
DDMC-p53 gene therapy with or without cisplatin and microwave ablation
Wolfgang Hohenforst-Schmidt, Paul Zarogoulidis, Joshua Stopek, Thomas Vogl, Frank Hübner, J Francis Turner, Robert Browning, Konstantinos Zarogoulidis, Antonis Drevelegas, Konstantinos Drevelegas, Kaid Darwiche, Lutz Freitag & Harald Rittger
Pages: 1165-1173
Published online: 20 May 2015
AbstractforDDMC-p53 gene therapy with or without cisplatin and microwave ablation | Full Text | References | PDF (6.1 MB)
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Article
AKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo
Yong Cui, Jing Lin, Jianling Zuo, Lei Zhang, Yan Dong, Guohan Hu, Chun Luo, Juxiang Chen & Yicheng Lu
Pages: 1681-1690
Published online: 08 Jul 2015
AbstractforAKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo | Full Text | References | PDF (2 MB)
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Case Report

Case Report
A spectrum of cutaneous toxicities from erlotinib may be a robust clinical marker for non-small-cell lung therapy: a case report and literature review
Feng Jin, Hui Zhu, Li Kong & Jinming Yu
Pages: 943-946
Published online: 23 Apr 2015
AbstractforA spectrum of cutaneous toxicities from erlotinib may be a robust clinical marker for non-small-cell lung therapy: a case report and literature review | Full Text | References | PDF (1.9 MB)
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Original Research

Article
Ability of PITX2 methylation to predict survival in patients with prostate cancer
Jiu-zhi Li, Yu Zhang, Bin Wen, Ming Li & Yu-jie Wang
Pages: 3507-3512
Published online: 28 Nov 2022
AbstractforAbility of PITX2 methylation to predict survival in patients with prostate cancer | PDF (856.6 KB)
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Article
Perioperative FOLFOX4 plus bevacizumab for initially unresectable advanced colorectal cancer (NAVIGATE-CRC-01)
Mitsukuni Suenaga, Yoshiya Fujimoto, Satoshi Matsusaka, Eiji Shinozaki, Takashi Akiyoshi, Satoshi Nagayama, Yosuke Fukunaga, Masatoshi Oya, Masashi Ueno, Nobuyuki Mizunuma & Toshiharu Yamaguchi
Pages: 1111-1118
Published online: 18 May 2015
AbstractforPerioperative FOLFOX4 plus bevacizumab for initially unresectable advanced colorectal cancer (NAVIGATE-CRC-01) | Full Text | References | PDF (503 KB)
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Case Report

Case Report
Severe thrombocytopenia after dasatinib treatment in a patient with Philadelphia chromosome-positive chronic myeloid leukemia
Runzhe Chen, Fei Wang, Xiaoping Zhang, Chong Gao & Baoan Chen
Pages: 955-957
Published online: 24 Apr 2015
AbstractforSevere thrombocytopenia after dasatinib treatment in a patient with Philadelphia chromosome-positive chronic myeloid leukemia | Full Text | References | PDF (213.8 KB)
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Original Research

Article
Association between EHBP1 rs721048(A>G) polymorphism and prostate cancer susceptibility: a meta-analysis of 17 studies involving 150,678 subjects
Xiang Ao, Ying Liu, Xiao-Yan Bai, Xinjian Qu, Zhaowei Xu, Gaolei Hu, Min Chen & Huijian Wu
Pages: 1671-1680
Published online: 07 Jul 2015
AbstractforAssociation between EHBP1 rs721048(A>G) polymorphism and prostate cancer susceptibility: a meta-analysis of 17 studies involving 150,678 subjects | Full Text | References | PDF (1.4 MB)
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Article
The predictive effect of overexpressed miR-34a on good survival of cancer patients: a systematic review and meta-analysis
Jian Wang, Guorong Dan, Jiqing Zhao, Yu Ding, Feng Ye, Huiqin Sun, Fan Jiang, Jin Cheng, Fahuan Yuan & Zhongmin Zou
Pages: 2709-2719
Published online: 25 Sep 2015
AbstractforThe predictive effect of overexpressed miR-34a on good survival of cancer patients: a systematic review and meta-analysis | Full Text | References | PDF (613.6 KB)
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Article
Determination and validation of mTOR kinase-domain 3D structure by homology modeling
Wiame Lakhlili, Gwénaël Chevé, Abdelaziz Yasri & Azeddine Ibrahimi
Pages: 1923-1930
Published online: 30 Jul 2015
AbstractforDetermination and validation of mTOR kinase-domain 3D structure by homology modeling | Full Text | References | PDF (2.7 MB)
  • 141 Views
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Article
Positive expression of programmed death ligand-1 correlates with superior outcomes and might be a therapeutic target in primary pulmonary lymphoepithelioma-like carcinoma
Li Jiang, Liang Wang, Peng-fei Li, Xin-ke Zhang, Jie-wei Chen, Hui-juan Qiu, Xiao-dong Wu & Bei Zhang
Pages: 1451-1457
Published online: 15 Jun 2015
AbstractforPositive expression of programmed death ligand-1 correlates with superior outcomes and might be a therapeutic target in primary pulmonary lymphoepithelioma-like carcinoma | Full Text | References | PDF (3 MB)
  • 57 Views
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Article
Clinicopathological significance of fascin-1 expression in patients with non-small cell lung cancer
Xiao-Ling Ling, Xiao-Ming Hou & Da Zhao
Pages: 1589-1595
Published online: 30 Jun 2015
AbstractforClinicopathological significance of fascin-1 expression in patients with non-small cell lung cancer | Full Text | References | PDF (2 MB)
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Article
CpG oligodeoxyribonucleotide 7909 enhances radiosensitivity via downregulating Oct-4 expression in radioresistant lung cancer cells
Na Xing, Tiankui Qiao, Xibing Zhuang, Sujuan Yuan, Qi Zhang & Guoxiong Xu
Pages: 1443-1449
Published online: 12 Jun 2015
AbstractforCpG oligodeoxyribonucleotide 7909 enhances radiosensitivity via downregulating Oct-4 expression in radioresistant lung cancer cells | Full Text | References | PDF (1.3 MB)
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Case Series

Could erlotinib treatment lead to acute cardiovascular events in patients with lung adenocarcinoma after chemotherapy failure?
Tulay Kus, Gokmen Aktas, Alper Sevinc, Mehmet Emin Kalender & Celaletdin Camci
Pages: 1341-1343
Published online: 05 Jun 2015
AbstractforCould erlotinib treatment lead to acute cardiovascular events in patients with lung adenocarcinoma after chemotherapy failure? | Full Text | References | PDF (129.3 KB)
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Original Research

Article
Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers
Hai-Xia Fan, Yan Chen, Bo-Xiong Ni, Shan Wang, Miao Sun, Dong Chen & Jin-Hua Zheng
Pages: 1619-1626
Published online: 03 Jul 2015
AbstractforExpression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers | Full Text | References | PDF (2.7 MB)
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Article
Cytochrome P450 1A1 exon 7 polymorphism and susceptibility to lung cancer in the Chinese population: an updated meta-analysis and review
Xiu-ping Wei & Jie Hu
Pages: 1611-1618
Published online: 02 Jul 2015
AbstractforCytochrome P450 1A1 exon 7 polymorphism and susceptibility to lung cancer in the Chinese population: an updated meta-analysis and review | Full Text | References | PDF (481.5 KB)
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Article
A study on the effect of IL-6 gene polymorphism on the prognosis of non-small-cell lung cancer
Wei Jia, Guang-He Fei, Jie-Gui Hu & Xian-Wei Hu
Pages: 2699-2704
Published online: 23 Sep 2015
AbstractforA study on the effect of IL-6 gene polymorphism on the prognosis of non-small-cell lung cancer | Full Text | References | PDF (534.9 KB)
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Case Series

Axillary and internal mammary sentinel lymph node biopsy in male breast cancer patients: case series and review
Xiaoshan Cao, Chunjian Wang, Yanbing Liu, Pengfei Qiu, Binbin Cong & Yongsheng Wang
Pages: 1499-1502
Published online: 17 Jun 2015
AbstractforAxillary and internal mammary sentinel lymph node biopsy in male breast cancer patients: case series and review | Full Text | References | PDF (142.7 KB)
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Original Research

Article
Prognostic role of HOTAIR in four estrogen-dependent malignant tumors: a meta-analysis
Jing Li, Wen Wen, Shu Zhao, Jingxuan Wang, Jingyu Chen, Yanrong Wang & Qingyuan Zhang
Pages: 1471-1482
Published online: 15 Jun 2015
AbstractforPrognostic role of HOTAIR in four estrogen-dependent malignant tumors: a meta-analysis | Full Text | References | PDF (1.3 MB)
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Article
No associations between aromatase gene polymorphisms and breast cancer risk in Saudi patients
Mohammed Alanazi, Huda A Alabdulkarim, Jilani P Shaik, Abdulrahman Al Naeem, Mohammad Elrobh, Abdullah Al Amri, Fatimah Basil al-Mukaynizi, Abdelhabib Semlali, Arjumand Warsy & Narasimha Reddy Parine
Pages: 2453-2459
Published online: 03 Sep 2015
AbstractforNo associations between aromatase gene polymorphisms and breast cancer risk in Saudi patients | Full Text | References | PDF (856.4 KB)
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Article
Percutaneous microwave ablation combined with simultaneous transarterial chemoembolization for the treatment of advanced intrahepatic cholangiocarcinoma
Guo-Wei Yang, Qing Zhao, Sheng Qian, Liang Zhu, Xu-Dong Qu, Wei Zhang, Zhi-Ping Yan, Jie-Min Cheng, Qing-Xin Liu, Rong Liu & Jian-Hua Wang
Pages: 1245-1250
Published online: 26 May 2015
AbstractforPercutaneous microwave ablation combined with simultaneous transarterial chemoembolization for the treatment of advanced intrahepatic cholangiocarcinoma | Full Text | References | PDF (1.3 MB)
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Article
Bortezomib-based vs non-bortezomib-based post-transplantation treatment in multiple myeloma patients: a systematic review and meta-analysis of Phase III randomized controlled trials
Xiaoping Liu, Colin K He, Xiangyu Meng, Li He, Kaili Li, Qing Liang, Liang Shao & Shangqin Liu
Pages: 1459-1469
Published online: 15 Jun 2015
AbstractforBortezomib-based vs non-bortezomib-based post-transplantation treatment in multiple myeloma patients: a systematic review and meta-analysis of Phase III randomized controlled trials | Full Text | References | PDF (837.8 KB)
  • 66 Views
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Article
A DNA vaccine encoding mutated HPV58 mE6E7-Fc-GPI fusion antigen and GM-CSF and B7.1
He Wang, Jiyun Yu & Li Li
Pages: 3067-3077
Published online: 23 Oct 2015
AbstractforA DNA vaccine encoding mutated HPV58 mE6E7-Fc-GPI fusion antigen and GM-CSF and B7.1 | Full Text | References | PDF (1 MB)
  • 55 Views
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Article
Detection of epidermal growth factor receptor mutation in lung cancer by droplet digital polymerase chain reaction
Qing Xu, Yazhen Zhu, Yali Bai, Xiumin Wei, Xirun Zheng, Mao Mao & Guangjuan Zheng
Pages: 1533-1541
Published online: 22 Jun 2015
AbstractforDetection of epidermal growth factor receptor mutation in lung cancer by droplet digital polymerase chain reaction | Full Text | References | PDF (651.1 KB)
  • 84 Views
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Article
Prognostic analysis of Chinese patients with metastasis renal cell cancer receiving sorafenib: results from a multicenter long-term follow-up retrospective study
Fang Guo, Tao Han, Zhaozhe Liu, Xishuang Song, Qifu Zhang, Xiangbo Kong, Changfu Li, Zhenhua Li, Chengge Li, Shuxian Qu, Zhendong Zheng, Ying Piao, Yaling Han & Xiaodong Xie
Pages: 1581-1588
Published online: 26 Jun 2015
AbstractforPrognostic analysis of Chinese patients with metastasis renal cell cancer receiving sorafenib: results from a multicenter long-term follow-up retrospective study | Full Text | References | PDF (1.3 MB)
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Review

Review Article
CAG repeat polymorphisms in the androgen receptor and breast cancer risk in women: a meta-analysis of 17 studies
Qixing Mao, Mantang Qiu, Gaochao Dong, Wenjie Xia, Shuai Zhang, Youtao Xu, Jie Wang, Yin Rong, Lin Xu & Feng Jiang
Pages: 2111-2120
Published online: 13 Aug 2015
AbstractforCAG repeat polymorphisms in the androgen receptor and breast cancer risk in women: a meta-analysis of 17 studies | Full Text | References | PDF (1.1 MB)
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Original Research

Article
miR-20b overexpression is predictive of poor prognosis in gastric cancer
Tong-min Xue, Li-de Tao, Miao Zhang, Guang-cai Xu, Jie Zhang & Pei-Jian Zhang
Pages: 1871-1876
Published online: 24 Jul 2015
AbstractformiR-20b overexpression is predictive of poor prognosis in gastric cancer | Full Text | References | PDF (1,002.2 KB)
  • 51 Views
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Article
Screening of feature genes in distinguishing different types of breast cancer using support vector machine
Qi Wang & Xudong Liu
Pages: 2311-2317
Published online: 27 Aug 2015
AbstractforScreening of feature genes in distinguishing different types of breast cancer using support vector machine | Full Text | References | PDF (851.6 KB)
  • 90 Views
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Article
B7-H3 silencing by RNAi inhibits tumor progression and enhances chemosensitivity in U937 cells
Wei Zhang, Jing Wang, Yanfang Wang, Fei Dong, Mingxia Zhu, Wenli Wan, Haishen Li, Feifei Wu, Xinxing Yan & Xiaoyan Ke
Pages: 1721-1733
Published online: 14 Jul 2015
AbstractforB7-H3 silencing by RNAi inhibits tumor progression and enhances chemosensitivity in U937 cells | Full Text | References | PDF (1.8 MB)
  • 92 Views
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Article
Comparison of the utility and applicability of the Sokal, Hasford, and EUTOS scores in a population of Chinese patients with chronic-phase chronic myeloid leukemia undergoing imatinib therapy
Leiming Xia, Wei Qian, Mingzhen Yang, Qingsheng Li, Fei Liu & Yanyan Xie
Pages: 2485-2492
Published online: 07 Sep 2015
AbstractforComparison of the utility and applicability of the Sokal, Hasford, and EUTOS scores in a population of Chinese patients with chronic-phase chronic myeloid leukemia undergoing imatinib therapy | Full Text | References | PDF (764.6 KB)
  • 64 Views
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Article
MTA1 promotes proliferation and invasion in human gastric cancer cells
Yuan Yao, Shuting Feng, Mingming Xiao, Yan Li, Li Yang & Jiao Gong
Pages: 1785-1794
Published online: 28 Nov 2022
AbstractforMTA1 promotes proliferation and invasion in human gastric cancer cells | PDF (4.2 MB)
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Article
The histone demethylase PHF8 promotes prostate cancer cell growth by activating the oncomiR miR-125b
Qiang Ma, Zhuo Chen, Guojin Jia, Xueqiang Lu, Xuefeng Xie & Wei Jin
Pages: 1979-1988
Published online: 10 Aug 2015
AbstractforThe histone demethylase PHF8 promotes prostate cancer cell growth by activating the oncomiR miR-125b | Full Text | References | PDF (1.1 MB)
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Case Report

Case Report
The role of 18F-FDG PET/CT imaging in patient with malignant PEComa treated with mTOR inhibitor
Lu Sun, Xiaorong Sun, Yuhui Li & Ligang Xing
Pages: 1967-1970
Published online: 30 Jul 2015
AbstractforThe role of 18F-FDG PET/CT imaging in patient with malignant PEComa treated with mTOR inhibitor | Full Text | References | PDF (2.1 MB)
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Original Research

Article
Low claudin-6 expression correlates with poor prognosis in patients with non-small cell lung cancer
Qiang Wang, Yan Zhang, Tao Zhang, Zhi-Gang Han & Li Shan
Pages: 1971-1977
Published online: 31 Jul 2015
AbstractforLow claudin-6 expression correlates with poor prognosis in patients with non-small cell lung cancer | Full Text | References | PDF (1.2 MB)
  • 90 Views
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Article
Prognostic value of FDG PET/CT in head and neck squamous cell carcinomas
D Dequanter, M Shahla, C Aubert, Y Deniz & P Lothaire
Pages: 2279-2283
Published online: 26 Aug 2015
AbstractforPrognostic value of FDG PET/CT in head and neck squamous cell carcinomas | Full Text | References | PDF (306 KB)
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Article
Differential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells
Isabel Acuña-Macías, Eunice Vera, Alma Yolanda Vázquez-Sánchez, María Eugenia Mendoza-Garrido & Javier Camacho
Pages: 2959-2965
Published online: 16 Oct 2015
AbstractforDifferential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells | Full Text | References | PDF (493.7 KB)
  • 56 Views
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Article
Association between the polymorphisms of urokinase plasminogen activation system and cancer risk: a meta-analysis
Zhen Xu, Li-Li Meng, Jizong Lin, Yunbiao Ling, Shu-xian Chen & Nan Lin
Pages: 2493-2502
Published online: 09 Sep 2015
AbstractforAssociation between the polymorphisms of urokinase plasminogen activation system and cancer risk: a meta-analysis | Full Text | References | PDF (713.7 KB)
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Article
Efficacy and safety of docetaxel for advanced non-small-cell lung cancer: a meta-analysis of Phase III randomized controlled trials
Xuan He, Ji Wang & Yuanmin Li
Pages: 2023-2031
Published online: 04 Aug 2015
AbstractforEfficacy and safety of docetaxel for advanced non-small-cell lung cancer: a meta-analysis of Phase III randomized controlled trials | Full Text | References | PDF (521.2 KB)
  • 91 Views
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Article
Hepatoma-derived growth factor predicts unfavorable prognosis of epithelial ovarian cancer
Xue-jun Liu, Wen-lian Liu, Fang-mei Yang, Xiao-qing Yang & Xiao-fei Lu
Pages: 2101-2109
Published online: 13 Aug 2015
AbstractforHepatoma-derived growth factor predicts unfavorable prognosis of epithelial ovarian cancer | Full Text | References | PDF (1.9 MB)
  • 59 Views
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Article
Overexpression of miR-100 inhibits cell proliferation, migration, and chemosensitivity in human glioblastoma through FGFR3
Yongxin Luan, Shuyan Zhang, Ling Zuo & Lixiang Zhou
Pages: 3391-3400
Published online: 17 Nov 2015
AbstractforOverexpression of miR-100 inhibits cell proliferation, migration, and chemosensitivity in human glioblastoma through FGFR3 | Full Text | References | PDF (2.7 MB)
  • 62 Views
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Article
Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas
Dan Cong, Mengzi He, Silin Chen, Xiaoli Liu, Xiaodong Liu & Hui Sun
Pages: 2271-2277
Published online: 26 Aug 2015
AbstractforExpression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas | Full Text | References | PDF (685.1 KB)
  • 63 Views
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Article
Cemented allograft-prosthesis composite reconstruction for the proximal femur tumor
Li Min, Fan Tang, Hong Duan, Yong Zhou, Wen-li Zhang, Rui Shi & Chong-qi Tu
Pages: 2261-2269
Published online: 25 Aug 2015
AbstractforCemented allograft-prosthesis composite reconstruction for the proximal femur tumor | Full Text | References | PDF (1.5 MB)
  • 69 Views
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Article
A polymorphism at the microRNA binding site in the 3′ untranslated region of RYR3 is associated with outcome in hepatocellular carcinoma
Chenxing Peng, Zhanjun Guo, Xiaoyan Wu & Xiao-lan Zhang
Pages: 2075-2079
Published online: 10 Aug 2015
AbstractforA polymorphism at the microRNA binding site in the 3′ untranslated region of RYR3 is associated with outcome in hepatocellular carcinoma | Full Text | References | PDF (390.2 KB)
  • 45 Views
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Article
p27Kip1 and Ser10-phosphorylated p27Kip1 in breast cancer: clinical significance and expression
Wei Song, Ruilian Xie, Aiyu Zhu, Yumei Xu, Yaqin Shi, Yan Shen, Wenwen Zhang, Fang Yang & Xiaoxiang Guan
Pages: 1863-1869
Published online: 24 Jul 2015
Abstractforp27Kip1 and Ser10-phosphorylated p27Kip1 in breast cancer: clinical significance and expression | Full Text | References | PDF (1.6 MB)
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Article
The prognostic significance of protein tyrosine phosphatase 4A2 in breast cancer
Duanzheng Zhao, Libin Guo, Henrique Neves, Hiu-Fung Yuen, Shu-Dong Zhang, Cian M McCrudden, Qing Wen, Jin Zhang, Qi Zeng, Hang Fai Kwok & Yao Lin
Pages: 1707-1717
Published online: 13 Jul 2015
AbstractforThe prognostic significance of protein tyrosine phosphatase 4A2 in breast cancer | Full Text | References | PDF (1.5 MB)
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Article
Disruption of NF-κB signaling by fluoxetine attenuates MGMT expression in glioma cells
Tao Song, Hui Li, Zhiliang Tian, Chaojiu Xu, Jingfang Liu & Yong Guo
Pages: 2199-2208
Published online: 20 Aug 2015
AbstractforDisruption of NF-κB signaling by fluoxetine attenuates MGMT expression in glioma cells | Full Text | References | PDF (1.7 MB)
  • 128 Views
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Article
Morphologic patterns and imaging features of intracranial hemangiopericytomas: a retrospective analysis
Haopeng Pang, Zhenwei Yao, Yan Ren, Guobing Liu, Jiawen Zhang & Xiaoyuan Feng
Pages: 2169-2178
Published online: 20 Aug 2015
AbstractforMorphologic patterns and imaging features of intracranial hemangiopericytomas: a retrospective analysis | Full Text | References | PDF (3.6 MB)
  • 69 Views
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Article
Combination of BCL-2 and MYC protein expression improves high-risk stratification in diffuse large B-cell lymphoma
Jing Wang, Min Zhou, Jing-Yan Xu, Bing Chen & Jian Ouyang
Pages: 2645-2650
Published online: 18 Sep 2015
AbstractforCombination of BCL-2 and MYC protein expression improves high-risk stratification in diffuse large B-cell lymphoma | Full Text | References | PDF (1 MB)
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Article
IL-2 -330T/G polymorphism and cancer risk: a meta-analysis
Hongyu Zhao & Rui Wang
Pages: 1753-1760
Published online: 17 Jul 2015
AbstractforIL-2 -330T/G polymorphism and cancer risk: a meta-analysis | Full Text | References | PDF (1.1 MB)
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Article
Heme oxygenase-1 is a predictive biomarker for therapeutic targeting of advanced clear cell renal cell carcinoma treated with sorafenib or sunitinib
Wan-Xiang Zheng, Fei Yan, Qin Xue, Guo-Jun Wu, Wei-Jun Qin, Fu-Li Wang, Jun Qin, Chun-Juan Tian & Jian-Lin Yuan
Pages: 2081-2088
Published online: 10 Aug 2015
AbstractforHeme oxygenase-1 is a predictive biomarker for therapeutic targeting of advanced clear cell renal cell carcinoma treated with sorafenib or sunitinib | Full Text | References | PDF (1 MB)
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Article
Clinical efficacy of percutaneous vertebroplasty combined with intensity-modulated radiotherapy for spinal metastases in patients with NSCLC
Yi Li, Yi Qing, Zhimin Zhang, Mengxia Li, Jiaying Xie, Ge Wang & Dong Wang
Pages: 2139-2145
Published online: 19 Aug 2015
AbstractforClinical efficacy of percutaneous vertebroplasty combined with intensity-modulated radiotherapy for spinal metastases in patients with NSCLC | Full Text | References | PDF (1,010.9 KB)
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Article
Treatment compliance and severe adverse events limit the use of tyrosine kinase inhibitors in refractory thyroid cancer
Alexandra Chrisoulidou, Stylianos Mandanas, Efterpi Margaritidou, Lemonia Mathiopoulou, Maria Boudina, Konstantinos Georgopoulos & Kalliopi Pazaitou-Panayiotou
Pages: 2435-2442
Published online: 03 Sep 2015
AbstractforTreatment compliance and severe adverse events limit the use of tyrosine kinase inhibitors in refractory thyroid cancer | Full Text | References | PDF (216.5 KB)
  • 92 Views
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Article
Single nucleotide polymorphisms of microRNA processing genes and outcome of non-Hodgkin’s lymphoma
Yuhuan Gao, Lanping Diao, Huan Li & Zhanjun Guo
Pages: 1735-1741
Published online: 15 Jul 2015
AbstractforSingle nucleotide polymorphisms of microRNA processing genes and outcome of non-Hodgkin’s lymphoma | Full Text | References | PDF (549.3 KB)
  • 65 Views
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Article
Role of NSC319726 in ovarian cancer based on the bioinformatics analyses
Ji Xue, Guang Yang, Hong Ding, Pu Wang & Changhong Wang
Pages: 3757-3765
Published online: 15 Dec 2015
AbstractforRole of NSC319726 in ovarian cancer based on the bioinformatics analyses | Full Text | References | PDF (3.7 MB)
  • 87 Views
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Article
Is there any association between hormonal contraceptives and cervical neoplasia in a poor Nigerian setting?
Leonard Ogbonna Ajah, Chibuike Ogwuegbu Chigbu, Benjamin Chukwuma Ozumba, Theophilus Chimezie Oguanuo & Paul Olisaemeka Ezeonu
Pages: 1887-1892
Published online: 27 Jul 2015
AbstractforIs there any association between hormonal contraceptives and cervical neoplasia in a poor Nigerian setting? | Full Text | References | PDF (303.2 KB)
  • 63 Views
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Article
Effects of magnetic nanoparticles of Fe3O4 combinated with gambogic acid on apoptosis of SMMC-7721 cells
Liang Tian, Bao-an Chen, Jian Cheng & Qing-long Guo
Pages: 2285-2290
Published online: 26 Aug 2015
AbstractforEffects of magnetic nanoparticles of Fe3O4 combinated with gambogic acid on apoptosis of SMMC-7721 cells | Full Text | References | PDF (1.1 MB)
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Case Series

Follicular dendritic cell sarcoma: two rare cases and a brief review of the literature
Yuan Ma, Jujie Sun, Cuicui Yang, Dandan Yuan & Jie Liu
Pages: 1823-1830
Published online: 24 Jul 2015
AbstractforFollicular dendritic cell sarcoma: two rare cases and a brief review of the literature | Full Text | References | PDF (4.3 MB)
  • 73 Views
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Case Report

Case Report
Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing
Hiroshi Ikeda, Kazuya Ishiguro, Tetsuyuki Igarashi, Yuka Aoki, Toshiaki Hayashi, Tadao Ishida, Yasushi Sasaki, Takashi Tokino & Yasuhisa Shinomura
Pages: 2805-2815
Published online: 05 Oct 2015
AbstractforMolecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing | Full Text | References | PDF (1.2 MB)
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Original Research

Article
Comparison of dynamic contrast-enhanced magnetic resonance imaging with T2-weighted imaging for preoperative staging of early endometrial carcinoma
Linfeng Zheng, Sujuan Zheng, Xiaochun Yuan, Xifu Wang, Zhuoli Zhang & Guixiang Zhang
Pages: 1743-1751
Published online: 17 Jul 2015
AbstractforComparison of dynamic contrast-enhanced magnetic resonance imaging with T2-weighted imaging for preoperative staging of early endometrial carcinoma | Full Text | References | PDF (2 MB)
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Article
The influence of TLR4 agonist lipopolysaccharides on hepatocellular carcinoma cells and the feasibility of its application in treating liver cancer
Junsheng Gu, Ranran Sun, Shen Shen & Zujiang Yu
Pages: 2215-2225
Published online: 28 Nov 2022
AbstractforThe influence of TLR4 agonist lipopolysaccharides on hepatocellular carcinoma cells and the feasibility of its application in treating liver cancer | PDF (2.5 MB)
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Article
Dynamic monitoring of plasma amino acids and carnitine during chemotherapy of patients with alimentary canal malignancies and its clinical value
Xiaoyu Wang, Jiaqi Wang, Zhenghua Wang, Qingjun Wang & Hua Li
Pages: 1989-1996
Published online: 07 Aug 2015
AbstractforDynamic monitoring of plasma amino acids and carnitine during chemotherapy of patients with alimentary canal malignancies and its clinical value | Full Text | References | PDF (337.5 KB)
  • 51 Views
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Article
Whole blood defensin mRNA expression is a predictive biomarker of docetaxel response in castration-resistant prostate cancer
Manish Kohli, Charles YF Young, Donald J Tindall, Debashis Nandy, Kyle M McKenzie, Graham H Bevan & Krishna Vanaja Donkena
Pages: 1915-1922
Published online: 30 Jul 2015
AbstractforWhole blood defensin mRNA expression is a predictive biomarker of docetaxel response in castration-resistant prostate cancer | Full Text | References | PDF (399.7 KB)
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Article
Three-dimensional conformal radiotherapy by delineations on CT-based simulation in different respiratory phases for the treatment of senile patients with non-small cell lung cancer
Weifeng Wang, Feng Yuan, Guoping Wang, Zhiren Lin, Yanling Pan & Longhua Chen
Pages: 2461-2467
Published online: 07 Sep 2015
AbstractforThree-dimensional conformal radiotherapy by delineations on CT-based simulation in different respiratory phases for the treatment of senile patients with non-small cell lung cancer | Full Text | References | PDF (501.8 KB)
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Article
−148 C/T polymorphism of Axin2 contributes to a decreased risk of cancer: evidence from a meta-analysis
AnYuan Zhong, Xue Pan, MinHua Shi & HuaJun Xu
Pages: 1957-1966
Published online: 29 Jul 2015
Abstractfor−148 C/T polymorphism of Axin2 contributes to a decreased risk of cancer: evidence from a meta-analysis | Full Text | References | PDF (725.8 KB)
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Article
Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury
Tomohiro Mizuno, Waichi Sato, Kazuhiro Ishikawa, Yuki Terao, Kazuo Takahashi, Yukihiro Noda, Yukio Yuzawa & Tadashi Nagamatsu
Pages: 1701-1706
Published online: 10 Jul 2015
AbstractforSignificance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury | Full Text | References | PDF (747.8 KB)
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Article
Microvascular invasion in hepatocellular carcinoma overexpression promotes cell proliferation and inhibits cell apoptosis of hepatocellular carcinoma via inhibiting miR-199a expression
Yang Shi, Qingwei Song, Shengcai Yu, Dianhe Hu & Xiaohu Zhuang
Pages: 2303-2310
Published online: 27 Aug 2015
AbstractforMicrovascular invasion in hepatocellular carcinoma overexpression promotes cell proliferation and inhibits cell apoptosis of hepatocellular carcinoma via inhibiting miR-199a expression | Full Text | References | PDF (543.1 KB)
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Article
Tamoxifen with ovarian function suppression versus tamoxifen alone as an adjuvant treatment for premenopausal breast cancer: a meta-analysis of published randomized controlled trials
Shunchao Yan, Kai Li, Xin Jiao & Huawei Zou
Pages: 1433-1441
Published online: 12 Jun 2015
AbstractforTamoxifen with ovarian function suppression versus tamoxifen alone as an adjuvant treatment for premenopausal breast cancer: a meta-analysis of published randomized controlled trials | Full Text | References | PDF (675.6 KB)
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Article
Expressions and clinical significance of autophagy-related markers Beclin1, LC3, and EGFR in human cervical squamous cell carcinoma
Yun-Feng Hu, Xia Lei, Hong-Yi Zhang, Jun-wei Ma, Wei-wei Yang, Min-lin Chen, Jie Cui & Hong Zhao
Pages: 2243-2249
Published online: 24 Aug 2015
AbstractforExpressions and clinical significance of autophagy-related markers Beclin1, LC3, and EGFR in human cervical squamous cell carcinoma | Full Text | References | PDF (1.5 MB)
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Article
The engineered Salmonella typhimurium inhibits tumorigenesis in advanced glioma
Jian-qiang Chen, Yue-fu Zhan, Wei Wang, Sheng-nan Jiang & Xiang-ying Li
Pages: 2555-2563
Published online: 15 Sep 2015
AbstractforThe engineered Salmonella typhimurium inhibits tumorigenesis in advanced glioma | Full Text | References | PDF (3 MB)
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Article
Urine microRNAs as biomarkers for bladder cancer: a diagnostic meta-analysis
Yidong Cheng, Xiaheng Deng, Xiao Yang, Pengchao Li, Xiaolei Zhang, Peng Li, Jun Tao, Qiang Lu & Zengjun Wang
Pages: 2089-2096
Published online: 11 Aug 2015
AbstractforUrine microRNAs as biomarkers for bladder cancer: a diagnostic meta-analysis | Full Text | References | PDF (648.2 KB)
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Article
Alteration of ASIC1 expression in clear cell renal cell carcinoma
Yan Li, Guoxiong Xu, Kai Huang, Jun Wang, Jihong Zhang, Jikai Liu, Zhanyu Wang & Gang Chen
Pages: 2121-2127
Published online: 14 Aug 2015
AbstractforAlteration of ASIC1 expression in clear cell renal cell carcinoma | Full Text | References | PDF (1.7 MB)
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Article
Changing attitudes toward needle biopsies of breast cancer in Shanghai: experience and current status over the past 8 years
Shuang Hao, Zhe-Bin Liu, Hong Ling, Jia-Jian Chen, Ju-Ping Shen, Wen-Tao Yang & Zhi-Min Shao
Pages: 2865-2871
Published online: 09 Oct 2015
AbstractforChanging attitudes toward needle biopsies of breast cancer in Shanghai: experience and current status over the past 8 years | Full Text | References | PDF (659 KB)
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Article
Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells
Fu-Chi Kang, Pei-Jung Chen, Bo-Syong Pan, Meng-Shao Lai, Yung-Chia Chen & Bu-Miin Huang
Pages: 2345-2360
Published online: 01 Sep 2015
AbstractforApoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells | Full Text | References | PDF (3.5 MB)
  • 68 Views
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Article
Associations between deepness of response and clinical outcomes among Japanese patients with metastatic colorectal cancer treated with second-line FOLFIRI plus cetuximab
Hiroki Osumi, Satoshi Matsusaka, Mitsukuni Suenaga, Eiji Shinozaki & Nobuyuki Mizunuma
Pages: 2005-2013
Published online: 06 Aug 2015
AbstractforAssociations between deepness of response and clinical outcomes among Japanese patients with metastatic colorectal cancer treated with second-line FOLFIRI plus cetuximab | Full Text | References | PDF (944.9 KB)
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Article
Correlation of 18F-fluoroethyl tyrosine positron-emission tomography uptake values and histomorphological findings by stereotactic serial biopsy in newly diagnosed brain tumors using a refined software tool
William Omar Contreras Lopez, Joacir Graciolli Cordeiro, Ulrich Albicker, Soroush Doostkam, Guido Nikkhah, Robert D Kirch, Michael Trippel & Thomas Reithmeier
Pages: 3803-3815
Published online: 17 Dec 2015
AbstractforCorrelation of 18F-fluoroethyl tyrosine positron-emission tomography uptake values and histomorphological findings by stereotactic serial biopsy in newly diagnosed brain tumors using a refined software tool | Full Text | References | PDF (3.8 MB)
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Article
EGFR gene-mutation status correlated with therapeutic decision making in lung adenocarcinoma
Yaoyao Ren, Yibing Yao, Qing Ma & Diansheng Zhong
Pages: 3017-3020
Published online: 20 Oct 2015
AbstractforEGFR gene-mutation status correlated with therapeutic decision making in lung adenocarcinoma | Full Text | References | PDF (173.3 KB)
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Article
Different setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy
Jiqing Su, Wen Chen, Huiyun Yang, Jidong Hong, Zijian Zhang, Guangzheng Yang, Li Li & Rui Wei
Pages: 2545-2553
Published online: 14 Sep 2015
AbstractforDifferent setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy | Full Text | References | PDF (1.4 MB)
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Case Report

Case Report
Rapidly progressive stage IVB mycosis fungoides treated with low-dose total skin electron beam therapy
Mudit Chowdhary, Ahmad A Kabbani, Parin Rimtepathip, David A Cole Jr & David J Cohen
Pages: 1597-1601
Published online: 01 Jul 2015
AbstractforRapidly progressive stage IVB mycosis fungoides treated with low-dose total skin electron beam therapy | Full Text | References | PDF (894.1 KB)
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Original Research

Article
Treatment and survival analyses of completely resected thymic carcinoma patients
Yanjiao Mao & Shixiu Wu
Pages: 2503-2507
Published online: 09 Sep 2015
AbstractforTreatment and survival analyses of completely resected thymic carcinoma patients | Full Text | References | PDF (411.7 KB)
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Article
Increased risk of severe infections in cancer patients treated with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis
Qing Ma, Li-Yan Gu, Yao-Yao Ren, Li-Li Zeng, Ting Gong & Dian-Sheng Zhong
Pages: 2361-2374
Published online: 28 Aug 2015
AbstractforIncreased risk of severe infections in cancer patients treated with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis | Full Text | References | PDF (1 MB)
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Case Report

Case Report
Mixed acinar-endocrine carcinoma of pancreas: A case report and brief review of the literature
Zhenzhen Liu, Chengyong Dong, Chengye Wang, Qinlong Liu, Deguang Sun & Liming Wang
Pages: 1633-1642
Published online: 03 Jul 2015
AbstractforMixed acinar-endocrine carcinoma of pancreas: A case report and brief review of the literature | Full Text | References | PDF (4.8 MB)
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Original Research

Article
Anti-DR5 mAb inhibits proliferation of human fibroblast-like synovial cells and reduces their cytokine secretion in vitro
Minping Zhang, Chunyan Shi, Chun Xia, Jin Yang, Xingyang Niu, Guohong Zhuang & Ping Yin
Pages: 2745-2755
Published online: 29 Sep 2015
AbstractforAnti-DR5 mAb inhibits proliferation of human fibroblast-like synovial cells and reduces their cytokine secretion in vitro | Full Text | References | PDF (2 MB)
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Article
Increased risk of developing lung cancer in Asian patients carrying the TERT rs2736098 G>A polymorphism: evidence from 3,354 cases and 3,518 controls
Zhenhua Yang, Xunlei Zhang, Surong Fang, Yan Tan, Haijun Yan, Wei Gu & Jianhong Wang
Pages: 2757-2765
Published online: 30 Sep 2015
AbstractforIncreased risk of developing lung cancer in Asian patients carrying the TERT rs2736098 G>A polymorphism: evidence from 3,354 cases and 3,518 controls | Full Text | References | PDF (613.1 KB)
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Article
Simultaneous hepatectomy and splenectomy versus hepatectomy alone for hepatocellular carcinoma complicated by hypersplenism: a meta-analysis
Wei Li, Shi-Qiang Shen, Shan-Min Wu, Zu-Bing Chen, Chao Hu & Rui-Chen Yan
Pages: 2129-2137
Published online: 19 Aug 2015
AbstractforSimultaneous hepatectomy and splenectomy versus hepatectomy alone for hepatocellular carcinoma complicated by hypersplenism: a meta-analysis | Full Text | References | PDF (633.9 KB)
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Article
Expression of CPEB4 in invasive ductal breast carcinoma and its prognostic significance
Hao-Ting Sun, Xin Wen, Tian Han, Zhen-Hua Liu, Shao-Bo Li, Ji-Gang Wang & Xiu-Ping Liu
Pages: 3499-3506
Published online: 26 Nov 2015
AbstractforExpression of CPEB4 in invasive ductal breast carcinoma and its prognostic significance | Full Text | References | PDF (2.4 MB)
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Review

Review Article
Implication of lncRNAs in pathogenesis of esophageal cancer
Wei-Wei Tang, Qingquan Wu, Su-Qing Li, Yu-Suo Tong, Zi-Hao Liu, Tong-Xin Yang, Yong Xu & Xiu-Feng Cao
Pages: 3219-3226
Published online: 03 Nov 2015
AbstractforImplication of lncRNAs in pathogenesis of esophageal cancer | Full Text | References | PDF (533.7 KB)
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Original Research

Article
Liposomal curcumin inhibits hypoxia-induced angiogenesis after transcatheter arterial embolization in VX2 rabbit liver tumors
Feng Dai, Xiuming Zhang, Wenrong Shen, Jun Chen, Liucheng Liu & Gejun Gao
Pages: 2601-2611
Published online: 15 Sep 2015
AbstractforLiposomal curcumin inhibits hypoxia-induced angiogenesis after transcatheter arterial embolization in VX2 rabbit liver tumors | Full Text | References | PDF (4.7 MB)
  • 64 Views
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Article
MicroRNA-212 inhibits hepatocellular carcinoma cell proliferation and induces apoptosis by targeting FOXA1
Huahua Tu, Gang Wei, Qinghe Cai, Xianxiang Chen, Zequn Sun, Caitao Cheng, Linfei Zhang, Yong Feng, Huadong Zhou, Bo Zhou & Tiancai Zeng
Pages: 2227-2235
Published online: 28 Nov 2022
AbstractforMicroRNA-212 inhibits hepatocellular carcinoma cell proliferation and induces apoptosis by targeting FOXA1 | PDF (2.5 MB)
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Review

Review Article
Potential role for mammalian target of rapamycin inhibitors as first-line therapy in hormone receptor–positive advanced breast cancer
J Thaddeus Beck
Pages: 3629-3638
Published online: 07 Dec 2015
AbstractforPotential role for mammalian target of rapamycin inhibitors as first-line therapy in hormone receptor–positive advanced breast cancer | Full Text | References | PDF (736.8 KB)
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Original Research

Article
Angiogenesis inhibitors rechallenge in patients with advanced non-small-cell lung cancer: a pooled analysis of randomized controlled trials
Lingdi Zhao, Wei Li, Huiying Zhang, Nan Hou, Lanwei Guo & Quanli Gao
Pages: 2775-2781
Published online: 03 Oct 2015
AbstractforAngiogenesis inhibitors rechallenge in patients with advanced non-small-cell lung cancer: a pooled analysis of randomized controlled trials | Full Text | References | PDF (435.8 KB)
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Article
Comparative study on individual aromatase inhibitors on cardiovascular safety profile: a network meta-analysis
Xihe Zhao, Lei Liu, Kai Li, Wusheng Li, Li Zhao & Huawei Zou
Pages: 2721-2730
Published online: 29 Sep 2015
AbstractforComparative study on individual aromatase inhibitors on cardiovascular safety profile: a network meta-analysis | Full Text | References | PDF (735.7 KB)
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Article
The prognosis factor of adjuvant radiation therapy after surgery in uterine sarcomas
Hai-Ling Hou, Mao-Bin Meng, Xiu-Li Chen, Lu-Jun Zhao, Li Zhu, Bai-Lin Zhang & Ping Wang
Pages: 2339-2344
Published online: 28 Aug 2015
AbstractforThe prognosis factor of adjuvant radiation therapy after surgery in uterine sarcomas | Full Text | References | PDF (458.5 KB)
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Article
Clinical significance of locoregional and systemic treatment in operable high-risk breast cancer patients with more than four positive axillary lymph nodes
Kai Yin, Liheng Zhou, Zhimin Shao, Wenjin Yin & Jinsong Lu
Pages: 2665-2673
Published online: 21 Sep 2015
AbstractforClinical significance of locoregional and systemic treatment in operable high-risk breast cancer patients with more than four positive axillary lymph nodes | Full Text | References | PDF (1.4 MB)
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Article
The association between miR-499 polymorphism and cancer susceptibility: a meta-analysis
Zhongfei Xu, Enjiao Zhang, Weiyi Duan, Changfu Sun, Shuang Bai & Xuexin Tan
Pages: 2179-2186
Published online: 20 Aug 2015
AbstractforThe association between miR-499 polymorphism and cancer susceptibility: a meta-analysis | Full Text | References | PDF (491 KB)
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Article
Postoperative intensity-modulated radiation therapy provides favorable local control and low toxicities in patients with soft tissue sarcomas in the extremities and trunk wall
Jianyang Wang, Shulian Wang, Yongwen Song, Xinfan Liu, Jing Jin, Weihu Wang, Zihao Yu, Yueping Liu & Yexiong Li
Pages: 2843-2847
Published online: 09 Oct 2015
AbstractforPostoperative intensity-modulated radiation therapy provides favorable local control and low toxicities in patients with soft tissue sarcomas in the extremities and trunk wall | Full Text | References | PDF (282.8 KB)
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Article
Prognostic value of IGF-1R expression in bone and soft tissue sarcomas: a meta-analysis
Junbo Liang, Binghao Li, Li Yuan & Zhaoming Ye
Pages: 1949-1955
Published online: 29 Jul 2015
AbstractforPrognostic value of IGF-1R expression in bone and soft tissue sarcomas: a meta-analysis | Full Text | References | PDF (452 KB)
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Article
Bioinformatics analyses of differentially expressed genes associated with bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma
Jingnan Sun, Xue Wen, Fengyan Jin, Yuying Li, Jifan Hu & Yunpeng Sun
Pages: 2681-2688
Published online: 22 Sep 2015
AbstractforBioinformatics analyses of differentially expressed genes associated with bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma | Full Text | References | PDF (1.7 MB)
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Article
Quantitative assessment of pre-miR-218 rs11134527 polymorphism and cancer risk in Chinese population
Hongyu Zhao & Rui Wang
Pages: 1859-1862
Published online: 24 Jul 2015
AbstractforQuantitative assessment of pre-miR-218 rs11134527 polymorphism and cancer risk in Chinese population | Full Text | References | PDF (376.2 KB)
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Article
Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
Rong-jiang Wang, Jian-er Tang, Yu Chen & Jian-guo Gao
Pages: 2415-2426
Published online: 02 Sep 2015
AbstractforDietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer | Full Text | References | PDF (1.2 MB)
  • 200 Views
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Article
The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis
Jieer Ying, Qi Xu, Bixia Liu, Gu Zhang, Lei Chen & Hongming Pan
Pages: 2427-2433
Published online: 01 Sep 2015
AbstractforThe expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis | Full Text | References | PDF (3.2 MB)
  • 157 Views
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Article
Micheliolide overcomes KLF4-mediated cisplatin resistance in breast cancer cells by downregulating glutathione
Yongsheng Jia, Chunze Zhang, Liyan Zhou, Huijun Xu, Yehui Shi & Zhongsheng Tong
Pages: 2319-2327
Published online: 28 Aug 2015
AbstractforMicheliolide overcomes KLF4-mediated cisplatin resistance in breast cancer cells by downregulating glutathione | Full Text | References | PDF (2.4 MB)
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Article
Bevacizumab plus chemotherapy as third- or later-line therapy in patients with heavily treated metastatic colorectal cancer
Qiong Yang, Chenxi Yin, Fangxin Liao, Yuanyuan Huang, Wenzhuo He, Chang Jiang, Guifang Guo, Bei Zhang & Liangping Xia
Pages: 2407-2413
Published online: 01 Sep 2015
AbstractforBevacizumab plus chemotherapy as third- or later-line therapy in patients with heavily treated metastatic colorectal cancer | Full Text | References | PDF (302.3 KB)
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Article
Meta-analysis of postoperative adjuvant chemotherapy without radiotherapy in early stage non-small cell lung cancer
Yuan-Yuan Chen, Lin-Wei Wang, Shu-Yi Wang, Bi-Bo Wu, Zhen-Meng Wang, Fang-Fang Chen & Bin Xiong
Pages: 2033-2043
Published online: 04 Aug 2015
AbstractforMeta-analysis of postoperative adjuvant chemotherapy without radiotherapy in early stage non-small cell lung cancer | Full Text | References | PDF (758 KB)
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Article
The clinical analysis of acute pancreatitis in colorectal cancer patients undergoing chemotherapy after operation
Yanlei Ji, Zhen Han, Limei Shao, Yunling Li, Long Zhao & Yuehuan Zhao
Pages: 2527-2533
Published online: 11 Sep 2015
AbstractforThe clinical analysis of acute pancreatitis in colorectal cancer patients undergoing chemotherapy after operation | Full Text | References | PDF (855.3 KB)
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Article
A human leucyl-tRNA synthetase as an anticancer target
Guangwei Gao, Ying Yao, Kun Li, Dhahiri Saidi Mashausi, Dongsheng Li, Hema Negi, Suchitra Kamle, Hao Chen, Zhenghua Wu, Huchen Zhou & Dawei Li
Pages: 2933-2942
Published online: 15 Oct 2015
AbstractforA human leucyl-tRNA synthetase as an anticancer target | Full Text | References | PDF (1.7 MB)
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Letter

Letter
Comparing two assays for clinical genomic profiling: the devil is in the data
Rachel M Squillace, Garrett M Frampton, Phil J Stephens, Jeffrey S Ross & Vincent A Miller
Pages: 2237-2242
Published online: 24 Aug 2015
First Page PreviewforComparing two assays for clinical genomic profiling: the devil is in the data | Full Text | References | PDF (216 KB)
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Original Research

Article
Combined olaparib and oxaliplatin inhibits tumor proliferation and induces G2/M arrest and γ-H2AX foci formation in colorectal cancer
Kaiwu Xu, Zhihui Chen, Yi Cui, Changjiang Qin, Yulong He & Xinming Song
Pages: 3047-3054
Published online: 20 Oct 2015
AbstractforCombined olaparib and oxaliplatin inhibits tumor proliferation and induces G2/M arrest and γ-H2AX foci formation in colorectal cancer | Full Text | References | PDF (1.5 MB)
  • 128 Views
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Article
GSTM1 null genotype may be associated with an increased nasopharyngeal cancer risk in South China: an updated meta-analysis and review
Yanni Li, Wuhanhui Wan, Ting Li, Jing Cao & Ge Xu
Pages: 2479-2484
Published online: 07 Sep 2015
AbstractforGSTM1 null genotype may be associated with an increased nasopharyngeal cancer risk in South China: an updated meta-analysis and review | Full Text | References | PDF (516.8 KB)
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Review

Review Article
The distinctive nature of adenocarcinoma of the lung
Giandomenico Roviello
Pages: 2399-2406
Published online: 02 Sep 2015
AbstractforThe distinctive nature of adenocarcinoma of the lung | Full Text | References | PDF (201.4 KB)
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Original Research

Article
Cetuximab could be more effective without prior bevacizumab treatment in metastatic colorectal cancer patients
Yasuyoshi Sato, Satoshi Matsusaka, Mitsukuni Suenaga, Eiji Shinozaki & Nobuyuki Mizunuma
Pages: 3329-3336
Published online: 11 Nov 2015
AbstractforCetuximab could be more effective without prior bevacizumab treatment in metastatic colorectal cancer patients | Full Text | References | PDF (712.4 KB)
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Article
Prognostic value of Bcl-2 expression in patients with non-small-cell lung cancer: a meta-analysis and systemic review
Jie Zhang, Shengfei Wang, Lei Wang, Rui Wang, Sufeng Chen, Bin Pan, Yihua Sun & Haiquan Chen
Pages: 3361-3369
Published online: 18 Nov 2015
AbstractforPrognostic value of Bcl-2 expression in patients with non-small-cell lung cancer: a meta-analysis and systemic review | Full Text | References | PDF (695.7 KB)
  • 63 Views
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Article
ESHAP chemotherapy is efficient in refractory/relapsed primary central nervous system lymphoma: report of four cases
Rodica Ungur, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Doinel Radeanu, Adriana Muresan & Mihnea Zdrenghea
Pages: 2771-2773
Published online: 01 Oct 2015
AbstractforESHAP chemotherapy is efficient in refractory/relapsed primary central nervous system lymphoma: report of four cases | Full Text | References | PDF (154.4 KB)
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Case Report

Case Report
Malignant glomus tumor of the lung with multiorgan metastases: case report and literature review
Liang-Liang Dong, En-Guo Chen, Irfan S Sheikh, Zhi-Nong Jiang, Ai-Hua Huang & Ke-Jing Ying
Pages: 1909-1914
Published online: 28 Jul 2015
AbstractforMalignant glomus tumor of the lung with multiorgan metastases: case report and literature review | Full Text | References | PDF (4.1 MB)
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Original Research

Article
MicroRNA-766 targeting regulation of SOX6 expression promoted cell proliferation of human colorectal cancer
Yong-chao Li, Chang-feng Li, Li-bo Chen, Dan-dan Li, Lei Yang, Jing-peng Jin & Bin Zhang
Pages: 2981-2988
Published online: 20 Oct 2015
AbstractforMicroRNA-766 targeting regulation of SOX6 expression promoted cell proliferation of human colorectal cancer | Full Text | References | PDF (1.7 MB)
  • 82 Views
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Article
Transarterial oily chemoembolization with lidamycin shows potent therapeutic efficacy in VX2 rabbit liver tumor
Genshen Zhong, Jinsong Qi, Shuhua Huo, Huichao Xue, Zhishan Xu, Jinsong Li, Yanjun Zhou, Minna Wu & Liang Li
Pages: 3079-3086
Published online: 22 Oct 2015
AbstractforTransarterial oily chemoembolization with lidamycin shows potent therapeutic efficacy in VX2 rabbit liver tumor | Full Text | References | PDF (2.5 MB)
  • 48 Views
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Article
Prognostic role of LSD1 in various cancers: evidence from a meta-analysis
Jin Wu, Lixia Hu, Yingying Du, Fanliang Kong & Yueyin Pan
Pages: 2565-2570
Published online: 15 Sep 2015
AbstractforPrognostic role of LSD1 in various cancers: evidence from a meta-analysis | Full Text | References | PDF (643.6 KB)
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Article
Retrospective study of irinotecan/cisplatin followed by etoposide/cisplatin or the reverse sequence in extensive-stage small cell lung cancer
Xiaoguang Xiao, Shujing Wang, Shu Xia, Man Zou, Yang Li, Yao Wei, Qi Mei & Yuan Chen
Pages: 2209-2214
Published online: 21 Aug 2015
AbstractforRetrospective study of irinotecan/cisplatin followed by etoposide/cisplatin or the reverse sequence in extensive-stage small cell lung cancer | Full Text | References | PDF (377.5 KB)
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Article
Polymorphism in miR-146a associated with clinical characteristics and outcomes in gastric cancer patients treated with adjuvant oxaliplatin and fluoropyrimidines
Yu-Qian Liao, Yu-Lu Liao, Jun Li, Li-Xiang Peng, Yi-Ye Wan & Rui Zhong
Pages: 2627-2633
Published online: 16 Sep 2015
AbstractforPolymorphism in miR-146a associated with clinical characteristics and outcomes in gastric cancer patients treated with adjuvant oxaliplatin and fluoropyrimidines | Full Text | References | PDF (513.4 KB)
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Article
Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition
Chungyoul Choe, Yong-Sung Shin, Changhoon Kim, So-Jung Choi, Jinseon Lee, So Young Kim, Yong Beom Cho & Jhingook Kim
Pages: 3665-3678
Published online: 07 Dec 2015
AbstractforCrosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition | Full Text | References | PDF (2.4 MB)
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Article
A common genetic variation in CEBPE and acute lymphoblastic leukemia: a meta-analysis of the available evidence
Xiao-Xia Zhang, Yue-Feng Du, Ya-Jing Zhai, Fan Gao, Yu-Juan Yang, Xian-Cang Ma, Jun Lu & Jie Zheng
Pages: 2443-2451
Published online: 07 Sep 2015
AbstractforA common genetic variation in CEBPE and acute lymphoblastic leukemia: a meta-analysis of the available evidence | Full Text | References | PDF (706.3 KB)
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Article
rs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population
Qiang-Hua Jiang, Hong-Xin Peng, Yi Zhang, Peng Tian, Zu-Lian Xi & Hao Chen
Pages: 3041-3045
Published online: 22 Oct 2015
Abstractforrs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population | Full Text | References | PDF (186.5 KB)
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Article
Treating patients with advanced rectal cancer and lateral pelvic lymph nodes with preoperative chemoradiotherapy based on pretreatment imaging
Yasunori Otowa, Kimihiro Yamashita, Kiyonori Kanemitsu, Yasuo Sumi, Masashi Yamamoto, Shingo Kanaji, Tatsuya Imanishi, Tetsu Nakamura, Satoshi Suzuki, Kenichi Tanaka & Yoshihiro Kakeji
Pages: 3169-3173
Published online: 29 Oct 2015
AbstractforTreating patients with advanced rectal cancer and lateral pelvic lymph nodes with preoperative chemoradiotherapy based on pretreatment imaging | Full Text | References | PDF (300 KB)
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Article
Association between pre-miR-27a functional polymorphism and risk of colorectal cancer in north Chinese Han population
Quan Bian, Jian-Jun Chen, Jun-Ping Gu & Jing Xu
Pages: 3003-3007
Published online: 19 Oct 2015
AbstractforAssociation between pre-miR-27a functional polymorphism and risk of colorectal cancer in north Chinese Han population | Full Text | References | PDF (208.1 KB)
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Article
Does night-shift work increase the risk of prostate cancer? a systematic review and meta-analysis
Dapang Rao, Haifeng Yu, Yu Bai, Xiangyi Zheng & Liping Xie
Pages: 2817-2826
Published online: 05 Oct 2015
AbstractforDoes night-shift work increase the risk of prostate cancer? a systematic review and meta-analysis | Full Text | References | PDF (835.8 KB)
  • 210 Views
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Article
NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway
Hong Wei, Hongbin Wang, Qiao Ji, Jiawei Sun, Lin Tao & Xianli Zhou
Pages: 3721-3730
Published online: 14 Dec 2015
AbstractforNRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway | Full Text | References | PDF (1.5 MB)
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Article
miR-21 inhibits the effects of cyclooxygenase-2 inhibitor NS398 on apoptosis and invasion in gastric cancer cells
Huanqing Li, Jian Cheng, Yuqing Mao, Miao Jiang & Xiaoming Fan
Pages: 3245-3253
Published online: 04 Nov 2015
AbstractformiR-21 inhibits the effects of cyclooxygenase-2 inhibitor NS398 on apoptosis and invasion in gastric cancer cells | Full Text | References | PDF (2.4 MB)
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Article
Novel prognostic genes of diffuse large B-cell lymphoma revealed by survival analysis of gene expression data
Chenglong Li, Biao Zhu, Jiao Chen & Xiaobing Huang
Pages: 3407-3413
Published online: 18 Nov 2015
AbstractforNovel prognostic genes of diffuse large B-cell lymphoma revealed by survival analysis of gene expression data | Full Text | References | PDF (1.3 MB)
  • 82 Views
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Article
Role of estrogen in lung cancer based on the estrogen receptor-epithelial mesenchymal transduction signaling pathways
Xiao-zhen Zhao, Yu Liu, Li-juan Zhou, Zhong-qi Wang, Zhong-hua Wu & Xiao-yuan Yang
Pages: 2849-2863
Published online: 09 Oct 2015
AbstractforRole of estrogen in lung cancer based on the estrogen receptor-epithelial mesenchymal transduction signaling pathways | Full Text | References | PDF (12.8 MB)
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Case Report

Case Report
Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
Dawei Chen, Yan Zhang, Fang Shi, Minghuan Li, Hui Zhu, Li Kong & Jinming Yu
Pages: 2767-2770
Published online: 01 Oct 2015
AbstractforSustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review | Full Text | References | PDF (638.9 KB)
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Case Report
Advanced lung adenocarcinoma with spinal cord metastasis successfully treated with second EGFR-TKI treatment: a case report and literature review
Xiaoyan Li, Hui Yang, Jing Zhao & Hongjun Gao
Pages: 2739-2743
Published online: 29 Sep 2015
AbstractforAdvanced lung adenocarcinoma with spinal cord metastasis successfully treated with second EGFR-TKI treatment: a case report and literature review | Full Text | References | PDF (1.1 MB)
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Original Research

Article
Correlations between plasma endothelin-1 levels and breakthrough pain in patients with cancer
Xue-bin Yan, Tuo-chao Peng & Dong Huang
Pages: 3703-3706
Published online: 08 Dec 2015
AbstractforCorrelations between plasma endothelin-1 levels and breakthrough pain in patients with cancer | Full Text | References | PDF (169.3 KB)
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Article
Polo-like kinase 2 acting as a promoter in human tumor cells with an abundance of TAp73
ZhengBo Hu, ZunYing Xu, XiaoHong Liao, Xiao Yang, Cao Dong, KuaDi Luk, AnMin Jin & Hai Lu
Pages: 3475-3488
Published online: 20 Nov 2015
AbstractforPolo-like kinase 2 acting as a promoter in human tumor cells with an abundance of TAp73 | Full Text | References | PDF (2.8 MB)
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Article
The impact of histological types on the efficacy of angiogenesis inhibitors in the treatment of advanced NSCLC: a meta-analysis of randomized controlled trials
Jian Zhang, Jie Liu, Huiguo Chen, Weibin Wu, Xiaojun Li, Yonghui Wu, Kai Zhang & Lijia Gu
Pages: 2375-2382
Published online: 31 Aug 2015
AbstractforThe impact of histological types on the efficacy of angiogenesis inhibitors in the treatment of advanced NSCLC: a meta-analysis of randomized controlled trials | Full Text | References | PDF (580.5 KB)
  • 38 Views
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Article
CXCL12 genetic variants as prognostic markers in nasopharyngeal carcinoma
Ruiwan Chen, Yafei Xu, Xiaojing Du, Na Liu, Yingqin Li, Qingmei He, Linglong Tang, Yanping Mao, Ying Sun, Lei Chen & Jun Ma
Pages: 2835-2842
Published online: 08 Oct 2015
AbstractforCXCL12 genetic variants as prognostic markers in nasopharyngeal carcinoma | Full Text | References | PDF (862.9 KB)
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Article
A high LDL-C to HDL-C ratio predicts poor prognosis for initially metastatic colorectal cancer patients with elevations in LDL-C
Fangxin Liao, Wenzhuo He, Chang Jiang, Chenxi Yin, Guifang Guo, Xuxian Chen, Huijuan Qiu, Yuming Rong, Bei Zhang, Dazhi Xu & Liangping Xia
Pages: 3135-3142
Published online: 27 Oct 2015
AbstractforA high LDL-C to HDL-C ratio predicts poor prognosis for initially metastatic colorectal cancer patients with elevations in LDL-C | Full Text | References | PDF (699.2 KB)
  • 114 Views
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Article
Long noncoding RNA CCAT2 promotes breast tumor growth by regulating the Wnt signaling pathway
Yi Cai, Jing He & Dong Zhang
Pages: 2657-2664
Published online: 21 Sep 2015
AbstractforLong noncoding RNA CCAT2 promotes breast tumor growth by regulating the Wnt signaling pathway | Full Text | References | PDF (1.4 MB)
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Article
Percutaneous CT-guided microwave ablation as maintenance after first-line treatment for patients with advanced NSCLC
Xiang Ni, Jun-Qing Han, Xin Ye & Zhi-Gang Wei
Pages: 3227-3235
Published online: 03 Nov 2015
AbstractforPercutaneous CT-guided microwave ablation as maintenance after first-line treatment for patients with advanced NSCLC | Full Text | References | PDF (1.2 MB)
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Letter

Letter
Expression of PD-1 by CD4+CD25+CD127low Treg cells in the peripheral blood of lung cancer patients
AnYuan Zhong, Xue Pan & MinHua Shi
Pages: 1831-1833
Published online: 23 Jul 2015
First Page PreviewforExpression of PD-1 by CD4+CD25+CD127low Treg cells in the peripheral blood of lung cancer patients | Full Text | References | PDF (339 KB)
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Original Research

Article
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma
Lu-Lu Zhai, Yang Wu, Chong-Yang Cai & Zhi-Gang Tang
Pages: 2827-2834
Published online: 07 Oct 2015
AbstractforUpregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma | Full Text | References | PDF (972.5 KB)
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Article
Thyroid transcription factor-1 expression is significantly associated with mutations in exon 21 of the epidermal growth factor receptor gene in Chinese patients with lung adenocarcinoma
Qingchun Zhao, Song Xu, Jinghao Liu, Ying Li, Yaguang Fan, Tao Shi, Sen Wei, Shou-Ching Tang, Hongyu Liu & Jun Chen
Pages: 2469-2478
Published online: 07 Sep 2015
AbstractforThyroid transcription factor-1 expression is significantly associated with mutations in exon 21 of the epidermal growth factor receptor gene in Chinese patients with lung adenocarcinoma | Full Text | References | PDF (1.9 MB)
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Article
miR-195 is a key regulator of Raf1 in thyroid cancer
Fangzheng Wang, Chuner Jiang, Quanquan Sun, Fenqin Yan, Lei Wang, Zhenfu Fu, Tongxin Liu & Fujun Hu
Pages: 3021-3028
Published online: 20 Oct 2015
AbstractformiR-195 is a key regulator of Raf1 in thyroid cancer | Full Text | References | PDF (1.5 MB)
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Case Report

Case Report
A metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy
Casey B Williams, Caitlin McMahon, Siraj M Ali, Mark Abramovitz, Kirstin A Williams, Jessica Klein, Heidi McKean, Roman Yelensky, Thomas J George Jr, Julia A Elvin, Salil Soman, Doron Lipson, Juliann Chmielecki, Deborah Morosini, Vincent A Miller, Philip J Stephens, Jeffrey S Ross & Brian Leyland-Jones
Pages: 3561-3564
Published online: 01 Dec 2015
AbstractforA metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy | Full Text | References | PDF (591.4 KB)
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Original Research

Article
Prognostic role of neutrophil to lymphocyte ratio in lung cancers: a meta-analysis including 7,054 patients
Qing-Tao Zhao, Yong Yang, Shun Xu, Xiao-Peng Zhang, Hui-En Wang, Hua Zhang, Zhi-Kang Wang, Zheng Yuan & Guo-Chen Duan
Pages: 2731-2738
Published online: 29 Sep 2015
AbstractforPrognostic role of neutrophil to lymphocyte ratio in lung cancers: a meta-analysis including 7,054 patients | Full Text | References | PDF (601.3 KB)
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Article
Association between the COMT Val158Met polymorphism and risk of cancer: evidence from 99 case–control studies
Quan Zhou, Yan Wang, Aihua Chen, Yaling Tao, Huamei Song, Wei Li, Jing Tao & Manzhen Zuo
Pages: 2791-2803
Published online: 05 Oct 2015
AbstractforAssociation between the COMT Val158Met polymorphism and risk of cancer: evidence from 99 case–control studies | Full Text | References | PDF (597.8 KB)
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Article
Perineural invasion correlates with postoperative distant metastasis and poor overall survival in patients with PT1–3N0M0 esophageal squamous cell carcinoma
Liming Sheng, Yongling Ji & Xianghui Du
Pages: 3153-3157
Published online: 27 Oct 2015
AbstractforPerineural invasion correlates with postoperative distant metastasis and poor overall survival in patients with PT1–3N0M0 esophageal squamous cell carcinoma | Full Text | References | PDF (394.9 KB)
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Case Report

Case Report
Diarrhea as initial manifestation of pulmonary artery intimal sarcoma: a case report and literature review
Xiaoling Xu, Ruifeng Zhang, Huihui Hu, Wu Ye, Jin Wang, Liying Chen, Lijun Qiu & Kejing Ying
Pages: 2651-2656
Published online: 18 Sep 2015
AbstractforDiarrhea as initial manifestation of pulmonary artery intimal sarcoma: a case report and literature review | Full Text | References | PDF (2.8 MB)
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Original Research

Article
miR-98 targets ITGB3 to inhibit proliferation, migration, and invasion of non-small-cell lung cancer
Ran Ni, Yongjie Huang & Jing Wang
Pages: 2689-2697
Published online: 22 Sep 2015
AbstractformiR-98 targets ITGB3 to inhibit proliferation, migration, and invasion of non-small-cell lung cancer | Full Text | References | PDF (1.5 MB)
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Article
The expression status and prognostic significance of programmed cell death 1 ligand 1 in gastrointestinal tract cancer: a systematic review and meta-analysis
Baohua Huang, Lei Chen, Cuixia Bao, Chengming Sun, Jie Li, Lipeng Wang & Xia Zhang
Pages: 2617-2625
Published online: 15 Sep 2015
AbstractforThe expression status and prognostic significance of programmed cell death 1 ligand 1 in gastrointestinal tract cancer: a systematic review and meta-analysis | Full Text | References | PDF (770.7 KB)
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Article
Forkhead box protein A1 is a prognostic predictor and promotes tumor growth of gastric cancer
Hongyu Ren, Pei Zhang, Yong Tang, Mengping Wu & Weikang Zhang
Pages: 3029-3039
Published online: 28 Nov 2022
AbstractforForkhead box protein A1 is a prognostic predictor and promotes tumor growth of gastric cancer | PDF (2.9 MB)
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Article
Increased serum levels of interleukin-10 predict poor prognosis in extranodal natural killer/T-cell lymphoma patients receiving asparaginase-based chemotherapy
Hua Wang, Liang Wang, ZhiJun Wuxiao, HuiQiang Huang, WenQi Jiang, ZhiMing Li, Yue Lu & ZhongJun Xia
Pages: 2589-2599
Published online: 14 Sep 2015
AbstractforIncreased serum levels of interleukin-10 predict poor prognosis in extranodal natural killer/T-cell lymphoma patients receiving asparaginase-based chemotherapy | Full Text | References | PDF (995.3 KB)
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Article
Potential therapeutic strategy for gastric cancer peritoneal metastasis by NKG2D ligands-specific T cells
Xianqiang Liu, Meili Sun, Shui Yu, Kai Liu, Xirui Li & Huan Shi
Pages: 3095-3104
Published online: 22 Oct 2015
AbstractforPotential therapeutic strategy for gastric cancer peritoneal metastasis by NKG2D ligands-specific T cells | Full Text | References | PDF (750.6 KB)
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Article
Hormone receptor status predicts the clinical outcome of human epidermal growth factor 2-positive metastatic breast cancer patients receiving trastuzumab therapy: a multicenter retrospective study
Yunchao Wang, Tao Sun, Donggui Wan, Lijun Sheng, Wei Li, Huayun Zhu, Yanping Li & Janice Lu
Pages: 3337-3348
Published online: 11 Nov 2015
AbstractforHormone receptor status predicts the clinical outcome of human epidermal growth factor 2-positive metastatic breast cancer patients receiving trastuzumab therapy: a multicenter retrospective study | Full Text | References | PDF (645 KB)
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Letter

Letter
Role of DFNA5 in hearing loss and cancer – a comment on Rakusic et al
Lieselot Croes, Ken Op de Beeck & Guy Van Camp
Pages: 2613-2615
Published online: 15 Sep 2015
First Page PreviewforRole of DFNA5 in hearing loss and cancer – a comment on Rakusic et al | Full Text | References | PDF (225.8 KB)
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Rapid Communication

Article
Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer
Bin-Bin Cong, Xiao-Shan Cao, Peng-Fei Qiu, Yan-Bing Liu, Tong Zhao, Peng Chen, Chun-Jian Wang, Zhao-Peng Zhang, Xiao Sun & Yong-Sheng Wang
Pages: 2705-2708
Published online: 24 Sep 2015
AbstractforValidation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer | Full Text | References | PDF (639.3 KB)
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Original Research

Article
Concurrent radiotherapy with oral fluoropyrimidine versus gemcitabine in locally advanced pancreatic cancer: a systematic review and meta-analysis
Yong-Feng Yang, Xiao-Hui Cao, Chao-En Bao & Xin Wan
Pages: 3315-3322
Published online: 09 Nov 2015
AbstractforConcurrent radiotherapy with oral fluoropyrimidine versus gemcitabine in locally advanced pancreatic cancer: a systematic review and meta-analysis | Full Text | References | PDF (580.6 KB)
  • 45 Views
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Article
SOX2 expression is associated with FGFR fusion genes and predicts favorable outcome in lung squamous cell carcinomas
Shanbo Zheng, Yunjian Pan, Rui Wang, Yuan Li, Chao Cheng, Xuxia Shen, Bin Li, Difan Zheng, Yihua Sun & Haiquan Chen
Pages: 3009-3016
Published online: 19 Oct 2015
AbstractforSOX2 expression is associated with FGFR fusion genes and predicts favorable outcome in lung squamous cell carcinomas | Full Text | References | PDF (1.8 MB)
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Case Series

Long-term administration of high doses of transdermal buprenorphine in cancer patients with severe neuropathic pain
Wojciech Leppert & Grzegorz Kowalski
Pages: 3621-3627
Published online: 04 Dec 2015
AbstractforLong-term administration of high doses of transdermal buprenorphine in cancer patients with severe neuropathic pain | Full Text | References | PDF (575.9 KB)
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Original Research

Article
Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis
Shanghui Zhou, Ling Chen, Mubarak Mashrah, Yun Zhu, Jiannan Liu, Xi Yang, Zhijing He, Lizhen Wang, Tingxiu Xiang, Zhigang Yao, Feng Guo, Wenjun Yang & Chenping Zhang
Pages: 2923-2931
Published online: 14 Oct 2015
AbstractforDeregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis | Full Text | References | PDF (3.5 MB)
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Article
Prognostic value of programmed cell death-ligand 1 expression in patients with non-small-cell lung cancer: evidence from an updated meta-analysis
Anyuan Zhong, Yufei Xing, Xue Pan, Minhua Shi & Huajun Xu
Pages: 3595-3601
Published online: 01 Dec 2015
AbstractforPrognostic value of programmed cell death-ligand 1 expression in patients with non-small-cell lung cancer: evidence from an updated meta-analysis | Full Text | References | PDF (499.4 KB)
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Article
Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial–mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells
Xince Huang, Shengjie Dai, Juji Dai, Yuwu Xiao, Yongyu Bai, Bicheng Chen & Mengtao Zhou
Pages: 2989-3001
Published online: 19 Oct 2015
AbstractforLuteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial–mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells | Full Text | References | PDF (3.8 MB)
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Article
Downregulation of microRNA-132 by DNA hypermethylation is associated with cell invasion in colorectal cancer
Jun Qin, Jing Ke, Junfei Xu, Feiran Wang, Youlang Zhou, Yasu Jiang & Zhiwei Wang
Pages: 3639-3648
Published online: 07 Dec 2015
AbstractforDownregulation of microRNA-132 by DNA hypermethylation is associated with cell invasion in colorectal cancer | Full Text | References | PDF (2.9 MB)
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Article
Correlation of C-X-C chemokine receptor 2 upregulation with poor prognosis and recurrence in human glioma
Liu Yang, Zenghui Liu, Ronghua Wu, Qi Yao, Zhikai Gu & Mei Liu
Pages: 3203-3209
Published online: 02 Nov 2015
AbstractforCorrelation of C-X-C chemokine receptor 2 upregulation with poor prognosis and recurrence in human glioma | Full Text | References | PDF (1.7 MB)
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Review

Review Article
EGFR-TKIs in adjuvant treatment of lung cancer: to give or not to give?
Aleksandar Milovancev, Vladimir Stojsic, Bojan Zaric, Tomi Kovacevic, Tatjana Sarcev, Branislav Perin, Konstantinos Zarogoulidis, Katerina Tsirgogianni, Lutz Freitag, Kaid Darwiche, Drosos Tsavlis, Athanasios Zissimopoulos, Grigoris Stratakos & Paul Zarogoulidis
Pages: 2915-2921
Published online: 13 Oct 2015
AbstractforEGFR-TKIs in adjuvant treatment of lung cancer: to give or not to give? | Full Text | References | PDF (341 KB)
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Original Research

Article
miR-122 inhibits metastasis and epithelial–mesenchymal transition of non-small-cell lung cancer cells
Haifeng Qin, Jiping Sha, Caixia Jiang, Xuemei Gao, Lili Qu, Haiying Yan, Tianjiao Xu, Qiyu Jiang & Hongjun Gao
Pages: 3175-3184
Published online: 29 Oct 2015
AbstractformiR-122 inhibits metastasis and epithelial–mesenchymal transition of non-small-cell lung cancer cells | Full Text | References | PDF (5.1 MB)
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Article
The expression and clinical significance of HDGF in osteosarcoma
Zhiguo Chen, Shenghai Qiu & Xiaofei Lu
Pages: 2509-2517
Published online: 09 Sep 2015
AbstractforThe expression and clinical significance of HDGF in osteosarcoma | Full Text | References | PDF (1.6 MB)
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Article
Baseline blood immunological profiling differentiates between Her2–breast cancer molecular subtypes: implications for immunomediated mechanisms of treatment response
Oana Tudoran, Oana Virtic, Loredana Balacescu, Carmen Lisencu, Bogdan Fetica, Claudia Gherman, Ovidiu Balacescu & Ioana Berindan-Neagoe
Pages: 3415-3423
Published online: 18 Nov 2015
AbstractforBaseline blood immunological profiling differentiates between Her2–breast cancer molecular subtypes: implications for immunomediated mechanisms of treatment response | Full Text | References | PDF (691.9 KB)
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Article
Dynamin-related protein 1 is involved in micheliolide-induced breast cancer cell death
Yongsheng Jia, Liyan Zhou, Chen Tian, Yehui Shi, Chen Wang & Zhongsheng Tong
Pages: 3371-3381
Published online: 16 Nov 2015
AbstractforDynamin-related protein 1 is involved in micheliolide-induced breast cancer cell death | Full Text | References | PDF (3.9 MB)
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Review

Review Article
Links between cancer stem cells and epithelial–mesenchymal transition
Sha-sha Wang, Jian Jiang, Xin-hua Liang & Ya-ling Tang
Pages: 2973-2980
Published online: 16 Oct 2015
AbstractforLinks between cancer stem cells and epithelial–mesenchymal transition | Full Text | References | PDF (619.3 KB)
  • 155 Views
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Original Research

Article
Assessing the potential value of long interspersed element-1 hypomethylation in colorectal cancer: evidence from retrospective studies
Jie-Ting Tang, Zhen-Hua Wang & Jing-Yuan Fang
Pages: 3265-3276
Published online: 05 Nov 2015
AbstractforAssessing the potential value of long interspersed element-1 hypomethylation in colorectal cancer: evidence from retrospective studies | Full Text | References | PDF (919.9 KB)
  • 40 Views
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Article
First-line chemotherapy in patients with metastatic gastroenteropancreatic neuroendocrine carcinoma
Alberto Bongiovanni, Nada Riva, Marianna Ricci, Chiara Liverani, Federico La Manna, Alessandro De Vita, Flavia Foca, Laura Mercatali, Stefano Severi, Dino Amadori & Toni Ibrahim
Pages: 3613-3619
Published online: 03 Dec 2015
AbstractforFirst-line chemotherapy in patients with metastatic gastroenteropancreatic neuroendocrine carcinoma | Full Text | References | PDF (554.6 KB)
  • 74 Views
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Article
SKF95365 induces apoptosis and cell-cycle arrest by disturbing oncogenic Ca2+ signaling in nasopharyngeal carcinoma cells
Jinyan Zhang, Jiazhang Wei, Qian He, Yan Lin, Rong Liang, Jiaxiang Ye, Zhe Zhang & Yongqiang Li
Pages: 3123-3133
Published online: 27 Oct 2015
AbstractforSKF95365 induces apoptosis and cell-cycle arrest by disturbing oncogenic Ca2+ signaling in nasopharyngeal carcinoma cells | Full Text | References | PDF (3.3 MB)
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Article
Use of taxane-containing induction chemotherapy in combination with concurrent chemoradiotherapy in Chinese patients with locally advanced nasopharyngeal carcinoma: a meta-analysis
Rui Tian, Hong Xun Ye, Bao Guo Zhang, Dong Ying Gu, Bing Wen Zhang, Zhi Pan Teng, Mao Yong Jin, Jin Fei Chen & Jian Wei Qi
Pages: 3255-3263
Published online: 05 Nov 2015
AbstractforUse of taxane-containing induction chemotherapy in combination with concurrent chemoradiotherapy in Chinese patients with locally advanced nasopharyngeal carcinoma: a meta-analysis | Full Text | References | PDF (493.7 KB)
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Article
Genetic polymorphisms of CYP1A1 and risk of leukemia: a meta-analysis
Jun Lu, Qian Zhao, Ya-Jing Zhai, Hai-Rong He, Li-Hong Yang, Fan Gao, Rong-Sheng Zhou, Jie Zheng & Xian-Cang Ma
Pages: 2883-2902
Published online: 12 Oct 2015
AbstractforGenetic polymorphisms of CYP1A1 and risk of leukemia: a meta-analysis | Full Text | References | PDF (1.3 MB)
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Article
Associations of polymorphisms in NAT2 gene with risk and metastasis of osteosarcoma in young Chinese population
Zhengxiang Huang, Li Yuan, Zhenghui Jiang & Dongliang Wang
Pages: 2675-2680
Published online: 22 Sep 2015
AbstractforAssociations of polymorphisms in NAT2 gene with risk and metastasis of osteosarcoma in young Chinese population | Full Text | References | PDF (241.2 KB)
  • 57 Views
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Article
MicroRNA-125a-5p regulates cancer cell proliferation and migration through NAIF1 in prostate carcinoma
Yi Fu & Fuhua Cao
Pages: 3827-3835
Published online: 17 Dec 2015
AbstractforMicroRNA-125a-5p regulates cancer cell proliferation and migration through NAIF1 in prostate carcinoma | Full Text | References | PDF (1.8 MB)
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Article
The XRCC1 Arg194Trp polymorphism is significantly associated with lung adenocarcinoma: a case-control study in an Eastern European Caucasian group
Andreea Cătană, Monica Pop, Bianca Domokos Hincu, Ioan V Pop, Felicia M Petrişor, Mihai D Porojan & Radu A Popp
Pages: 3533-3538
Published online: 27 Nov 2015
AbstractforThe XRCC1 Arg194Trp polymorphism is significantly associated with lung adenocarcinoma: a case-control study in an Eastern European Caucasian group | Full Text | References | PDF (254.5 KB)
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Article
Incidence and clinical significance of ESR1 mutations in heavily pretreated metastatic breast cancer patients
Jiaxin Niu, Grant Andres, Kim Kramer, Madappa N Kundranda, Ricardo H Alvarez, Eiko Klimant, Ankur R Parikh, Bradford Tan, Edgar D Staren & Maurie Markman
Pages: 3323-3328
Published online: 11 Nov 2015
AbstractforIncidence and clinical significance of ESR1 mutations in heavily pretreated metastatic breast cancer patients | Full Text | References | PDF (239.6 KB)
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Review

Review Article
The functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapy
Chengxin Luan, Zixue Yang & Baoan Chen
Pages: 2903-2914
Published online: 13 Oct 2015
AbstractforThe functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapy | Full Text | References | PDF (1.4 MB)
  • 253 Views
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Original Research

Article
Yttrium-90 radioembolization for advanced inoperable hepatocellular carcinoma
Victor Ho-Fun Lee, Dennis KC Leung, Mai-Yee Luk, Chi-Chung Tong, Martin WM Law, Sherry CY Ng, Ka-Kin Wong, Ronnie TP Poon, Dora LW Kwong & To-Wai Leung
Pages: 3457-3464
Published online: 20 Nov 2015
AbstractforYttrium-90 radioembolization for advanced inoperable hepatocellular carcinoma | Full Text | References | PDF (410 KB)
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Article
Consolidation therapy of arsenic trioxide alternated with chemotherapy achieves remarkable efficacy in newly diagnosed acute promyelocytic leukemia
Cheng-cheng Liu, Hua Wang, Wei-da Wang, Meng-yuan Zhu, Qi-rong Geng & Yue Lu
Pages: 3297-3303
Published online: 12 Nov 2015
AbstractforConsolidation therapy of arsenic trioxide alternated with chemotherapy achieves remarkable efficacy in newly diagnosed acute promyelocytic leukemia | Full Text | References | PDF (401.3 KB)
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Article
Inhibition of TGF-β signaling with halofuginone can enhance the antitumor effect of irradiation in Lewis lung cancer
Runlong Lin, Shuai Yi, Linlin Gong, Weishuai Liu, Peng Wang, Ningbo Liu, Lujun Zhao & Ping Wang
Pages: 3549-3559
Published online: 02 Dec 2015
AbstractforInhibition of TGF-β signaling with halofuginone can enhance the antitumor effect of irradiation in Lewis lung cancer | Full Text | References | PDF (6 MB)
  • 80 Views
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Article
Concurrent chemoradiotherapy using paclitaxel plus cisplatin in the treatment of elderly patients with esophageal cancer
Tao Song, Xuebang Zhang, Min Fang & Shixiu Wu
Pages: 3087-3094
Published online: 22 Oct 2015
AbstractforConcurrent chemoradiotherapy using paclitaxel plus cisplatin in the treatment of elderly patients with esophageal cancer | Full Text | References | PDF (565 KB)
  • 61 Views
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Article
The association between XRCC1 Arg399Gln polymorphism and risk of leukemia in different populations: a meta-analysis of case-control studies
Fang Wang, Qian Zhao, Hai-rong He, Ya-jing Zhai, Jun Lu, Hai-bo Hu, Jin-song Zhou, Yong-hua Yang & Yuan-jie Li
Pages: 3277-3287
Published online: 06 Nov 2015
AbstractforThe association between XRCC1 Arg399Gln polymorphism and risk of leukemia in different populations: a meta-analysis of case-control studies | Full Text | References | PDF (778.9 KB)
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Article
Management experiences of primary angiosarcoma of breast: a retrospective study from single institute in the People’s Republic of China
Qun-Chao Hu, Xin Mei, Yan Feng, Jin-Li Ma, Zhao-Zhi Yang, Zhi-Min Shao, Xiao-Li Yu & Xiao-Mao Guo
Pages: 3237-3243
Published online: 04 Nov 2015
AbstractforManagement experiences of primary angiosarcoma of breast: a retrospective study from single institute in the People’s Republic of China | Full Text | References | PDF (1.5 MB)
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Case Report

Case Report
Non-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review
Yuan Yu, Xuemei Qin, Shuxin Yan, Wenxia Wang, Yanlin Sun & Maohong Zhang
Pages: 3707-3713
Published online: 10 Dec 2015
AbstractforNon-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review | Full Text | References | PDF (3 MB)
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Original Research

Article
Inhibitive effects of 15-deoxy-Δ12,14-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis
Kan Chen, Weiqi Dai, Fan Wang, Yujing Xia, Jingjing Li, Sainan Li, Tong Liu, Rong Zhang, Jianrong Wang, Wenxia Lu, Yuqing Zhou, Qin Yin, Yuanyuan Zheng, Huerxidan Abudumijiti, Rongxia Chen, Jie Lu, Yingqun Zhou & Chuanyong Guo
Pages: 3585-3593
Published online: 01 Dec 2015
AbstractforInhibitive effects of 15-deoxy-Δ12,14-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis | Full Text | References | PDF (2.6 MB)
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Article
High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma
Nan-bo Liu, Jun-hua Zhang, Yu-fan Liu, Jun Li, Zhen-zhong Zhang, Ji-wei Li, Wen-yue Liu, Chen Huang, Tao Shen, Cheng-wei Gu, Dong-yun Gao, Xia Wu & Xu Wu
Pages: 3449-3455
Published online: 19 Nov 2015
AbstractforHigh DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma | Full Text | References | PDF (1.7 MB)
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Article
Prognostic value of Notch-1 expression in hepatocellular carcinoma: a meta-analysis
Tao Wu, Min Jiao, Li Jing, Min-Cong Wang, Hai-Feng Sun, Qing Li, Yi-Yang Bai, Yong-Chang Wei, Ke-Jun Nan & Hui Guo
Pages: 3105-3114
Published online: 22 Oct 2015
AbstractforPrognostic value of Notch-1 expression in hepatocellular carcinoma: a meta-analysis | Full Text | References | PDF (653.8 KB)
  • 66 Views
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Article
Incidence and clinical characteristics of unexpected uterine sarcoma after hysterectomy and myomectomy for uterine fibroids: a retrospective study of 10,248 cases
Wan-Cheng Zhao, Fang-Fang Bi, Da Li & Qing Yang
Pages: 2943-2948
Published online: 15 Oct 2015
AbstractforIncidence and clinical characteristics of unexpected uterine sarcoma after hysterectomy and myomectomy for uterine fibroids: a retrospective study of 10,248 cases | Full Text | References | PDF (209.6 KB)
  • 95 Views
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Article
MicroRNA-328 enhances cellular motility through posttranscriptional regulation of PTPRJ in human hepatocellular carcinoma
Xiaoling Luo, Shiyan Yang, Chuanwen Zhou, Feng Pan, Qianjun Li & Shijie Ma
Pages: 3159-3167
Published online: 28 Oct 2015
AbstractforMicroRNA-328 enhances cellular motility through posttranscriptional regulation of PTPRJ in human hepatocellular carcinoma | Full Text | References | PDF (1.7 MB)
  • 74 Views
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Article
Serum dickkopf-1 as a biomarker in screening gastrointestinal cancers: a systematic review and meta-analysis
Bin Liang, Liansheng Zhong, Qun He, Shaocheng Wang, Zhongcheng Pan, Tianjiao Wang & Yujie Zhao
Pages: 3115-3122
Published online: 22 Oct 2015
AbstractforSerum dickkopf-1 as a biomarker in screening gastrointestinal cancers: a systematic review and meta-analysis | Full Text | References | PDF (1,003.2 KB)
  • 72 Views
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Article
Experience with combination of nimotuzumab and intensity-modulated radiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma
Rui-ping Zhai, Hong-mei Ying, Fang-fang Kong, Cheng-run Du, Shuang Huang, Jun-jun Zhou & Chao-su Hu
Pages: 3383-3390
Published online: 18 Nov 2015
AbstractforExperience with combination of nimotuzumab and intensity-modulated radiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma | Full Text | References | PDF (491.7 KB)
  • 64 Views
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Article
Prognostic and clinicopathological significance of serum interleukin-6 expression in colorectal cancer: a systematic review and meta-analysis
Zhen Wang, Pin Wu, Dang Wu, Zhigang Zhang, Guoming Hu, Shuai Zhao, Yucheng Lai & Jian Huang
Pages: 3793-3801
Published online: 16 Dec 2015
AbstractforPrognostic and clinicopathological significance of serum interleukin-6 expression in colorectal cancer: a systematic review and meta-analysis | Full Text | References | PDF (1.1 MB)
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Article
Relationship between high-mobility group box 1 overexpression in ovarian cancer tissue and serum: a meta-analysis
Haipeng Wang, Zengjun Li, Yanlai Sun, Zhongfa Xu, Jianjun Han, Bao Song, Wentao Song, Chen Qin & Lei Yin
Pages: 3523-3531
Published online: 27 Nov 2015
AbstractforRelationship between high-mobility group box 1 overexpression in ovarian cancer tissue and serum: a meta-analysis | Full Text | References | PDF (899.1 KB)
  • 56 Views
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Article
Mutation analysis underlying the downregulation of the thyroid hormone receptor β1 gene in the Chinese breast cancer population
Yaqin Ling, Xiaoling Ling, Lu Fan, Yong Wang & Qing Li
Pages: 2967-2972
Published online: 16 Oct 2015
AbstractforMutation analysis underlying the downregulation of the thyroid hormone receptor β1 gene in the Chinese breast cancer population | Full Text | References | PDF (1.2 MB)
  • 87 Views
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Article
Differences in clinical features between laparoscopy and open resection for primary tumor in patients with stage IV colorectal cancer
Ik Yong Kim, Bo Ra Kim, Hyun Soo Kim & Young Wan Kim
Pages: 3441-3448
Published online: 19 Nov 2015
AbstractforDifferences in clinical features between laparoscopy and open resection for primary tumor in patients with stage IV colorectal cancer | Full Text | References | PDF (545.7 KB)
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Article
Expression and prognostic value of GalNAc-T3 in patients with completely resected small (≤2 cm) peripheral lung adenocarcinoma after IASLC/ATS/ERS classification
Shilei Zhao, Tao Guo, Jinxiu Li, Hidetaka Uramoto, Hongwei Guan, Wuguo Deng & Chundong Gu
Pages: 3143-3152
Published online: 27 Oct 2015
AbstractforExpression and prognostic value of GalNAc-T3 in patients with completely resected small (≤2 cm) peripheral lung adenocarcinoma after IASLC/ATS/ERS classification | Full Text | References | PDF (3.6 MB)
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Article
The association of GSTT1 deletion polymorphism with lung cancer risk among Chinese population: evidence based on a cumulative meta-analysis
Yadong Wang, Haiyan Yang & Haiyu Wang
Pages: 2875-2882
Published online: 12 Oct 2015
AbstractforThe association of GSTT1 deletion polymorphism with lung cancer risk among Chinese population: evidence based on a cumulative meta-analysis | Full Text | References | PDF (629.5 KB)
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Review

Review Article
Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker
Florentina Serban, Stefan-Alexandru Artene, Ada Maria Georgescu, Stefana Oana Purcaru, Daniela Elise Tache, Oana Alexandru & Anica Dricu
Pages: 3767-3774
Published online: 16 Dec 2015
AbstractforEpidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker | Full Text | References | PDF (1 MB)
  • 85 Views
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Original Research

Article
Impact of age on the prognosis after liver transplantation for patients with hepatocellular carcinoma: a single-center experience
Pusen Wang, Chunguang Wang, Hao Li, Baojie Shi, Jianning Wang & Lin Zhong
Pages: 3775-3781
Published online: 16 Dec 2015
AbstractforImpact of age on the prognosis after liver transplantation for patients with hepatocellular carcinoma: a single-center experience | Full Text | References | PDF (601.5 KB)
  • 54 Views
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Article
The association between osteopontin and survival in non-small-cell lung cancer patients: a meta-analysis of 13 cohorts
Ying Wang, Jin Yang, Hui Liu, Ji-Rui Bi, Ying Liu, Yan-Yan Chen, Ji-Yu Cao & You-Jin Lu
Pages: 3513-3521
Published online: 26 Nov 2015
AbstractforThe association between osteopontin and survival in non-small-cell lung cancer patients: a meta-analysis of 13 cohorts | Full Text | References | PDF (775 KB)
  • 53 Views
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Article
Impact of more detailed categorization of shrinkage or progression ratio at initial imaging response after sorafenib treatment in advanced hepatocellular carcinoma patients
Yoshiyuki Wada, Yuko Takami, Masaki Tateishi, Tomoki Ryu, Kazuhiro Mikagi & Hideki Saitsu
Pages: 3193-3202
Published online: 02 Nov 2015
AbstractforImpact of more detailed categorization of shrinkage or progression ratio at initial imaging response after sorafenib treatment in advanced hepatocellular carcinoma patients | Full Text | References | PDF (576.6 KB)
  • 48 Views
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Article
Detection of epidermal growth factor receptor mutation in plasma as a biomarker in Chinese patients with early-stage non-small cell lung cancer
Kai Guo, ZhiPei Zhang, Lu Han, Jing Han, Jian Wang, YongAn Zhou, HongGang Liu, LiPing Tong, XiaoFei Li & XiaoLong Yan
Pages: 3289-3296
Published online: 06 Nov 2015
AbstractforDetection of epidermal growth factor receptor mutation in plasma as a biomarker in Chinese patients with early-stage non-small cell lung cancer | Full Text | References | PDF (418.4 KB)
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Article
Diagnostic value of SHOX2 DNA methylation in lung cancer: a meta-analysis
Qing-Tao Zhao, Tao Guo, Hui-En Wang, Xiao-Peng Zhang, Hua Zhang, Zhi-Kang Wang, Zheng Yuan & Guo-Chen Duan
Pages: 3433-3439
Published online: 19 Nov 2015
AbstractforDiagnostic value of SHOX2 DNA methylation in lung cancer: a meta-analysis | Full Text | References | PDF (815 KB)
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Article
Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1
Liwei Dong, Hongge Wang, Jiajing Niu, Mingwei Zou, Nuoting Wu, Debin Yu, Ye Wang & Zhihua Zou
Pages: 3649-3664
Published online: 08 Dec 2015
AbstractforEchinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1 | Full Text | References | PDF (3.4 MB)
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Article
Ultrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors
Cheng-Shi Chen, Qing Zhao, Sheng Qian, Hai-Liang Li, Chen-Yang Guo, Wei Zhang, Zhi-Ping Yan, Rong Liu & Jian-Hua Wang
Pages: 3539-3548
Published online: 27 Nov 2015
AbstractforUltrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors | Full Text | References | PDF (2.6 MB)
  • 87 Views
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Article
Prognostic impact of initial maximum standardized uptake value of 18F-FDG PET/CT on treatment response in patients with metastatic lung adenocarcinoma treated with erlotinib
Tulay Kus, Gokmen Aktas, Alper Sevinc, Mehmet Emin Kalender, Mustafa Yilmaz, Seval Kul, Serdar Oztuzcu, Cemil Oktay & Celaletdin Camci
Pages: 3749-3756
Published online: 15 Dec 2015
AbstractforPrognostic impact of initial maximum standardized uptake value of 18F-FDG PET/CT on treatment response in patients with metastatic lung adenocarcinoma treated with erlotinib | Full Text | References | PDF (334.1 KB)
  • 51 Views
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Article
The relationship between UGT1A1 gene polymorphism and irinotecan effect on extensive-stage small-cell lung cancer
Xiao-guang Xiao, Shu Xia, Man Zou, Qi Mei, Lei Zhou, Shu-jing Wang & Yuan Chen
Pages: 3575-3583
Published online: 03 Dec 2015
AbstractforThe relationship between UGT1A1 gene polymorphism and irinotecan effect on extensive-stage small-cell lung cancer | Full Text | References | PDF (899.8 KB)
  • 78 Views
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Article
Effect of gyromagnetic fields on human prostatic adenocarcinoma cells
Hongen Lei, Yongde Xu, Ruili Guan, Meng Li, Yu Hui, Zhezhu Gao, Bicheng Yang & Zhongcheng Xin
Pages: 3489-3497
Published online: 24 Nov 2015
AbstractforEffect of gyromagnetic fields on human prostatic adenocarcinoma cells | Full Text | References | PDF (2.4 MB)
  • 50 Views
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Article
Association between MDM2 SNP309 T>G polymorphism and the risk of bladder cancer: new data in a Chinese population and an updated meta-analysis
Linguo Xie, Yan Sun, Tao Chen, Dawei Tian, Yujuan Li, Yu Zhang, Na Ding, Zhonghua Shen, Hao Xu, Xuewu Nian, Nan Sha, Ruifa Han, Hailong Hu & Changli Wu
Pages: 3679-3690
Published online: 07 Dec 2015
AbstractforAssociation between MDM2 SNP309 T>G polymorphism and the risk of bladder cancer: new data in a Chinese population and an updated meta-analysis | Full Text | References | PDF (1.2 MB)
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Article
Inhibition of FOXO1 by small interfering RNA enhances proliferation and inhibits apoptosis of papillary thyroid carcinoma cells via Akt/FOXO1/Bim pathway
Hong-ming Song, Jia-lu Song, Deng-feng Li, Kai-yao Hua, Bing-kun Zhao & Lin Fang
Pages: 3565-3573
Published online: 01 Dec 2015
AbstractforInhibition of FOXO1 by small interfering RNA enhances proliferation and inhibits apoptosis of papillary thyroid carcinoma cells via Akt/FOXO1/Bim pathway | Full Text | References | PDF (2 MB)
  • 68 Views
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Review

Review Article
The role of CD44 in epithelial–mesenchymal transition and cancer development
Hanxiao Xu, Yijun Tian, Xun Yuan, Hua Wu, Qian Liu, Richard G Pestell & Kongming Wu
Pages: 3783-3792
Published online: 16 Dec 2015
AbstractforThe role of CD44 in epithelial–mesenchymal transition and cancer development | Full Text | References | PDF (1.8 MB)
  • 384 Views
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Original Research

Article
Restoration of BRG1 inhibits proliferation and metastasis of lung cancer by regulating tumor suppressor miR-148b
Zheng Zhou, Yanhe Su & Xianen Fa
Pages: 3603-3612
Published online: 02 Dec 2015
AbstractforRestoration of BRG1 inhibits proliferation and metastasis of lung cancer by regulating tumor suppressor miR-148b | Full Text | References | PDF (1.4 MB)
  • 60 Views
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Article
Validation of a quantitative 12-multigene expression assay (Oncotype DX® Colon Cancer Assay) in Korean patients with stage II colon cancer: implication of ethnic differences contributing to differences in gene expression
Duck Hyoun Jeong, Woo Ram Kim, Byung Soh Min, Young Wan Kim, Mi Kyung Song & Nam Kyu Kim
Pages: 3817-3825
Published online: 17 Dec 2015
AbstractforValidation of a quantitative 12-multigene expression assay (Oncotype DX® Colon Cancer Assay) in Korean patients with stage II colon cancer: implication of ethnic differences contributing to differences in gene expression | Full Text | References | PDF (788.2 KB)
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Article
Impact of lymphovascular invasion on recurrence and progression rates in patients with pT1 urothelial carcinoma of bladder after transurethral resection
Nan Sha, Linguo Xie, Tao Chen, Chen Xing, Xiaoteng Liu, Yu Zhang, Zhonghua Shen, Hao Xu, Zhouliang Wu, Hailong Hu & Changli Wu
Pages: 3401-3406
Published online: 18 Nov 2015
AbstractforImpact of lymphovascular invasion on recurrence and progression rates in patients with pT1 urothelial carcinoma of bladder after transurethral resection | Full Text | References | PDF (453 KB)
  • 40 Views
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Article
Utility of gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage in premenopausal women with breast cancer: a systematic review and meta-analysis
Yan-Wei Shen, Xiao-Man Zhang, Meng Lv, Ling Chen, Tian-Jie Qin, Fan Wang, Jiao Yang, Pei-Jun Liu & Jin Yang
Pages: 3349-3359
Published online: 13 Nov 2015
AbstractforUtility of gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage in premenopausal women with breast cancer: a systematic review and meta-analysis | Full Text | References | PDF (777 KB)
  • 90 Views
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Letter

Letter
Comparing two assays for clinical genomic profiling: the devil is in the data [Letter of clarification]
Glen J Weiss & Vivek Khemka
Page: 2643
Published online: 18 Sep 2015
CitationforComparing two assays for clinical genomic profiling: the devil is in the data [Letter of clarification] | Full Text | References | PDF (157.6 KB)
  • 41 Views
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Original Research

Article
GIT1 is a novel prognostic biomarker and facilitates tumor progression via activating ERK/MMP9 signaling in hepatocellular carcinoma
Junyi Chen, Pinghua Yang, Jue Yang, Zhijian Wen, Baohua Zhang & Xin Zheng
Pages: 3731-3742
Published online: 15 Dec 2015
AbstractforGIT1 is a novel prognostic biomarker and facilitates tumor progression via activating ERK/MMP9 signaling in hepatocellular carcinoma | Full Text | References | PDF (3 MB)
  • 55 Views
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Letter

Letter
Study of internal mammary sentinel lymph node biopsy in breast cancer patients after neoadjuvant chemotherapy
Xiao-Shan Cao, Bin-Bin Cong, Xiao Sun, Peng-Fei Qiu & Yong-Sheng Wang
Pages: 2873-2874
Published online: 09 Oct 2015
CitationforStudy of internal mammary sentinel lymph node biopsy in breast cancer patients after neoadjuvant chemotherapy | Full Text | References | PDF (159.8 KB)
  • 43 Views
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Letter
Comparative study on individual aromatase inhibitors on cardiovascular safety profile: misleading analysis and doubtful methodology
Wenqin Guo & Lang Li
Pages: 3465-3466
Published online: 20 Nov 2015
CitationforComparative study on individual aromatase inhibitors on cardiovascular safety profile: misleading analysis and doubtful methodology | Full Text | References | PDF (168.3 KB)
  • 39 Views
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